HIST1H2AH

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mucosal immune response (GO:0002385)8.10701648
2organ or tissue specific immune response (GO:0002251)7.32881821
3DNA replication-dependent nucleosome assembly (GO:0006335)6.97687010
4DNA replication-dependent nucleosome organization (GO:0034723)6.97687010
5chromatin assembly (GO:0031497)5.96390392
6regulation of histone H3-K9 methylation (GO:0051570)5.90073987
7DNA unwinding involved in DNA replication (GO:0006268)5.38128421
8nucleosome assembly (GO:0006334)5.29063463
9DNA replication initiation (GO:0006270)4.97344839
10protein localization to kinetochore (GO:0034501)4.94791525
11nuclear pore organization (GO:0006999)4.83702192
12nuclear pore complex assembly (GO:0051292)4.75493528
13chromatin assembly or disassembly (GO:0006333)4.68273770
14nucleosome organization (GO:0034728)4.64264140
15DNA strand elongation involved in DNA replication (GO:0006271)4.56055791
16protein-DNA complex assembly (GO:0065004)4.52336560
17mitotic sister chromatid segregation (GO:0000070)4.52280570
18regulation of posttranscriptional gene silencing (GO:0060147)4.51407018
19regulation of gene silencing by miRNA (GO:0060964)4.51407018
20regulation of gene silencing by RNA (GO:0060966)4.51407018
21protein localization to chromosome, centromeric region (GO:0071459)4.46316529
22IMP biosynthetic process (GO:0006188)4.44446585
23sister chromatid segregation (GO:0000819)4.43152215
24mitotic chromosome condensation (GO:0007076)4.33751303
25DNA strand elongation (GO:0022616)4.32683919
26protoporphyrinogen IX metabolic process (GO:0046501)4.29160311
27telomere maintenance via semi-conservative replication (GO:0032201)4.18763670
28folic acid-containing compound biosynthetic process (GO:0009396)4.18209592
29protein-DNA complex subunit organization (GO:0071824)4.10056089
30mitotic nuclear envelope disassembly (GO:0007077)4.00650086
31negative regulation of histone methylation (GO:0031061)3.97774954
32chromatin remodeling at centromere (GO:0031055)3.92704214
33negative regulation of hematopoietic progenitor cell differentiation (GO:1901533)3.92666324
34kinetochore organization (GO:0051383)3.92522641
35DNA replication checkpoint (GO:0000076)3.91360087
36CENP-A containing nucleosome assembly (GO:0034080)3.88228574
37viral mRNA export from host cell nucleus (GO:0046784)3.87264281
38protoporphyrinogen IX biosynthetic process (GO:0006782)3.85153024
39IMP metabolic process (GO:0046040)3.81256785
40regulation of gene silencing (GO:0060968)3.79241715
41nuclear envelope disassembly (GO:0051081)3.74551020
42membrane disassembly (GO:0030397)3.74551020
43antibacterial humoral response (GO:0019731)3.73960433
44mitotic metaphase plate congression (GO:0007080)3.72077552
45mitotic recombination (GO:0006312)3.70632477
46DNA duplex unwinding (GO:0032508)3.69697812
47DNA geometric change (GO:0032392)3.69065705
48telomere maintenance via recombination (GO:0000722)3.66407791
49positive regulation of chromosome segregation (GO:0051984)3.64069179
50regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.62800455
51pre-miRNA processing (GO:0031054)3.58687064
52DNA replication-independent nucleosome organization (GO:0034724)3.58225979
53DNA replication-independent nucleosome assembly (GO:0006336)3.58225979
54pore complex assembly (GO:0046931)3.57377152
55innate immune response in mucosa (GO:0002227)3.56401919
56DNA synthesis involved in DNA repair (GO:0000731)3.53223461
57antimicrobial humoral response (GO:0019730)3.51917543
58regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.50363693
59regulation of centriole replication (GO:0046599)3.49030665
60protein K6-linked ubiquitination (GO:0085020)3.48453395
61regulation of centrosome cycle (GO:0046605)3.43370242
62positive regulation of mitotic sister chromatid separation (GO:1901970)3.43358795
63positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.43358795
64positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.43358795
65double-strand break repair via nonhomologous end joining (GO:0006303)3.42496882
66non-recombinational repair (GO:0000726)3.42496882
67mitotic sister chromatid cohesion (GO:0007064)3.42362090
68ribosomal small subunit assembly (GO:0000028)3.40815286
69regulation of translational fidelity (GO:0006450)3.39038722
70attachment of spindle microtubules to kinetochore (GO:0008608)3.37971643
71dosage compensation (GO:0007549)3.37446076
72metaphase plate congression (GO:0051310)3.35934533
73regulation of spindle organization (GO:0090224)3.35709172
74telomere maintenance via telomere lengthening (GO:0010833)3.31175241
75nucleotide-excision repair, DNA gap filling (GO:0006297)3.30946130
76protein complex localization (GO:0031503)3.30608758
77kinetochore assembly (GO:0051382)3.30359147
78DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla3.28626813
79nucleobase biosynthetic process (GO:0046112)3.28380435
80negative regulation of chromosome segregation (GO:0051985)3.27492317
81meiotic chromosome segregation (GO:0045132)3.26359532
82mitochondrial DNA metabolic process (GO:0032042)3.24072073
83ribosomal small subunit biogenesis (GO:0042274)3.23691418
84porphyrin-containing compound biosynthetic process (GO:0006779)3.22977308
85histone exchange (GO:0043486)3.20859543
86maturation of SSU-rRNA (GO:0030490)3.20274139
87DNA ligation (GO:0006266)3.19920459
88nucleobase-containing small molecule interconversion (GO:0015949)3.18145538
89V(D)J recombination (GO:0033151)3.16887562
90cellular protein complex localization (GO:0034629)3.13583916
91somatic hypermutation of immunoglobulin genes (GO:0016446)3.13493848
92somatic diversification of immune receptors via somatic mutation (GO:0002566)3.13493848
93rRNA transcription (GO:0009303)3.12878490
94viral transcription (GO:0019083)3.11449711
95establishment of chromosome localization (GO:0051303)3.09995657
96regulation of translational termination (GO:0006449)3.09376222
97protein localization to chromosome (GO:0034502)3.09080118
98regulation of mitotic sister chromatid separation (GO:0010965)3.09009764
99regulation of mitotic sister chromatid segregation (GO:0033047)3.09009764
100regulation of sister chromatid segregation (GO:0033045)3.09009764
101regulation of mammary gland epithelial cell proliferation (GO:0033599)3.08515013
102defense response to Gram-positive bacterium (GO:0050830)3.07699473
103granulocyte differentiation (GO:0030851)3.07620106
104DNA conformation change (GO:0071103)3.07277642
105maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.06853620
106regulation of mitotic spindle organization (GO:0060236)3.06701966
107regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.06550256
108regulation of mitotic metaphase/anaphase transition (GO:0030071)3.06550256
109spindle checkpoint (GO:0031577)3.06441428
110erythrocyte maturation (GO:0043249)3.05455505
111regulation of chromosome segregation (GO:0051983)3.05277872
112translational termination (GO:0006415)3.04464232
113negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.03324549
114negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.03324549
115negative regulation of mitotic sister chromatid segregation (GO:0033048)3.03324549
116negative regulation of mitotic sister chromatid separation (GO:2000816)3.03324549
117negative regulation of sister chromatid segregation (GO:0033046)3.03324549
118translesion synthesis (GO:0019985)3.03037903
119mitotic spindle assembly checkpoint (GO:0007094)3.01969879
120regulation of megakaryocyte differentiation (GO:0045652)3.01753865
121chromosome condensation (GO:0030261)3.00455627
122regulation of sister chromatid cohesion (GO:0007063)3.00274495
123spindle assembly checkpoint (GO:0071173)2.98576332
124DNA damage response, signal transduction resulting in transcription (GO:0042772)2.98540360
125regulation of helicase activity (GO:0051095)2.98153962
126regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.98041008
127microtubule depolymerization (GO:0007019)2.97672904
128regulation of centrosome duplication (GO:0010824)2.95617884
129DNA topological change (GO:0006265)2.95284089
130regulation of spindle checkpoint (GO:0090231)2.93216409
131postreplication repair (GO:0006301)2.93147505
132telomere maintenance (GO:0000723)2.92801502
133telomere organization (GO:0032200)2.91571701
134ATP-dependent chromatin remodeling (GO:0043044)2.91394129
135proline biosynthetic process (GO:0006561)2.91153629
136chromosome segregation (GO:0007059)2.91052804
137positive regulation of histone methylation (GO:0031062)2.87395176

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.68471091
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.84755600
3E2F4_17652178_ChIP-ChIP_JURKAT_Human4.42028089
4* SMAD1_18555785_ChIP-Seq_MESCs_Mouse3.27533506
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.21514005
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.01331199
7MYC_18555785_ChIP-Seq_MESCs_Mouse2.99641577
8* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.45518519
9HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.36038000
10* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.31746463
11MYC_19079543_ChIP-ChIP_MESCs_Mouse2.29027911
12TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.19567713
13* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.18395621
14* E2F1_21310950_ChIP-Seq_MCF-7_Human2.16290437
15FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse10.3112569
16BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.92345378
17POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.84989005
18* SOX2_16153702_ChIP-ChIP_HESCs_Human1.84452853
19MYC_18358816_ChIP-ChIP_MESCs_Mouse1.83661857
20NANOG_18555785_ChIP-Seq_MESCs_Mouse1.79794322
21SOX2_18555785_ChIP-Seq_MESCs_Mouse1.77256748
22ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.75255891
23CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.74901818
24POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.71264649
25* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.70914803
26AR_21909140_ChIP-Seq_LNCAP_Human1.67021605
27EGR1_19374776_ChIP-ChIP_THP-1_Human1.64770105
28KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.58523214
29XRN2_22483619_ChIP-Seq_HELA_Human1.57246214
30KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.56487781
31MYC_22102868_ChIP-Seq_BL_Human1.54450538
32VDR_23849224_ChIP-Seq_CD4+_Human1.52313521
33EST1_17652178_ChIP-ChIP_JURKAT_Human1.51569626
34HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.49412261
35STAT3_1855785_ChIP-Seq_MESCs_Mouse1.47857256
36KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.45681047
37* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.45006961
38* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.44736894
39* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.44418583
40THAP11_20581084_ChIP-Seq_MESCs_Mouse1.43654953
41CREB1_15753290_ChIP-ChIP_HEK293T_Human1.42001322
42KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.41604824
43MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.40365713
44ETS1_20019798_ChIP-Seq_JURKAT_Human1.39497788
45* RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.39086929
46IRF1_19129219_ChIP-ChIP_H3396_Human1.35256663
47* HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.33985532
48* SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.33301004
49TCF3_18692474_ChIP-Seq_MESCs_Mouse1.32863891
50ESR1_15608294_ChIP-ChIP_MCF-7_Human1.32309737
51EGR1_23403033_ChIP-Seq_LIVER_Mouse1.32182668
52* POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.30992343
53CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.29836641
54MYCN_18555785_ChIP-Seq_MESCs_Mouse1.29435965
55ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.25845225
56HOXB4_20404135_ChIP-ChIP_EML_Mouse1.25768534
57* SOX2_18692474_ChIP-Seq_MESCs_Mouse1.24854694
58FOXP3_21729870_ChIP-Seq_TREG_Human1.23361080
59* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.20721164
60POU5F1_16153702_ChIP-ChIP_HESCs_Human1.20212649
61NANOG_16153702_ChIP-ChIP_HESCs_Human1.19113182
62CIITA_25753668_ChIP-Seq_RAJI_Human1.16184569
63SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.13660920
64HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.13196677
65JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.11663888
66DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.09246025
67ZFX_18555785_ChIP-Seq_MESCs_Mouse1.07981487
68KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.07332555
69KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.07332555
70KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.07332555
71ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.07185178
72GABP_17652178_ChIP-ChIP_JURKAT_Human1.06437266
73ELK1_19687146_ChIP-ChIP_HELA_Human1.04484890
74TTF2_22483619_ChIP-Seq_HELA_Human1.03805001
75TCF3_18692474_ChIP-Seq_MEFs_Mouse1.02004557
76VDR_21846776_ChIP-Seq_THP-1_Human1.01735849
77NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.01086526
78YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.00415952
79MYC_18940864_ChIP-ChIP_HL60_Human1.00147083
80GATA1_22025678_ChIP-Seq_K562_Human0.98919963
81DCP1A_22483619_ChIP-Seq_HELA_Human0.98569191
82KDM5A_27292631_Chip-Seq_BREAST_Human0.96759121
83SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.96531900
84NANOG_21062744_ChIP-ChIP_HESCs_Human0.96221871
85* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.95945912
86NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.95160605
87NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.93114462
88DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.93006901
89KLF4_18555785_ChIP-Seq_MESCs_Mouse0.92768082
90PADI4_21655091_ChIP-ChIP_MCF-7_Human0.91552374
91TP63_19390658_ChIP-ChIP_HaCaT_Human0.88831105
92GABP_19822575_ChIP-Seq_HepG2_Human0.88509467
93NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.87642942
94* STAT4_19710469_ChIP-ChIP_TH1__Mouse0.87170776
95SALL1_21062744_ChIP-ChIP_HESCs_Human0.85935600
96SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.85657385
97E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.85373755
98PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.84598608
99ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.84229103
100POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.83527571
101MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.83326730
102YY1_21170310_ChIP-Seq_MESCs_Mouse0.82363203
103CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.81162676
104ELF1_17652178_ChIP-ChIP_JURKAT_Human0.80816925
105SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.80485033
106* ETS1_22383799_ChIP-Seq_G1ME_Mouse0.78010758
107TFEB_21752829_ChIP-Seq_HELA_Human0.77924000
108SOX2_18692474_ChIP-Seq_MEFs_Mouse0.77903534
109SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.77517838
110NOTCH1_21737748_ChIP-Seq_TLL_Human0.76824282
111VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.73825881
112PKCTHETA_26484144_Chip-Seq_BREAST_Human0.73614600
113BRD4_27068464_Chip-Seq_AML-cells_Mouse0.72329880
114CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.71277086
115FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.71220224
116PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.68697888
117CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.67905340
118SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.66309381
119ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.63620958
120SRF_21415370_ChIP-Seq_HL-1_Mouse0.62998973
121FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.62411322

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003111_abnormal_nucleus_morphology4.81788615
2MP0010094_abnormal_chromosome_stability4.77327165
3MP0003693_abnormal_embryo_hatching4.35674812
4MP0003077_abnormal_cell_cycle3.77614814
5MP0004957_abnormal_blastocyst_morpholog3.76547624
6MP0008057_abnormal_DNA_replication3.52132553
7MP0003656_abnormal_erythrocyte_physiolo3.09194159
8MP0010352_gastrointestinal_tract_polyps2.97468840
9MP0010307_abnormal_tumor_latency2.88147733
10MP0008058_abnormal_DNA_repair2.73663369
11MP0002009_preneoplasia2.72137892
12MP0004147_increased_porphyrin_level2.57939343
13MP0003123_paternal_imprinting2.51105056
14MP0001730_embryonic_growth_arrest2.45516522
15MP0008932_abnormal_embryonic_tissue2.44995992
16MP0000350_abnormal_cell_proliferation2.41435692
17MP0009697_abnormal_copulation2.38185911
18MP0008007_abnormal_cellular_replicative2.22997447
19MP0003705_abnormal_hypodermis_morpholog2.17270289
20MP0001661_extended_life_span2.08525260
21MP0001697_abnormal_embryo_size2.00784481
22MP0004185_abnormal_adipocyte_glucose1.98738907
23MP0005380_embryogenesis_phenotype1.92249155
24MP0001672_abnormal_embryogenesis/_devel1.92249155
25MP0005076_abnormal_cell_differentiation1.89264981
26MP0002084_abnormal_developmental_patter1.89081657
27MP0002086_abnormal_extraembryonic_tissu1.87248722
28MP0002085_abnormal_embryonic_tissue1.86324372
29MP0003890_abnormal_embryonic-extraembry1.84537026
30MP0003121_genomic_imprinting1.78726949
31MP0004197_abnormal_fetal_growth/weight/1.77984110
32MP0004133_heterotaxia1.77606839
33MP0002080_prenatal_lethality1.71873253
34MP0008877_abnormal_DNA_methylation1.70714087
35MP0005397_hematopoietic_system_phenotyp1.67183678
36MP0001545_abnormal_hematopoietic_system1.67183678
37MP0003984_embryonic_growth_retardation1.66041574
38MP0000490_abnormal_crypts_of1.65678290
39MP0002088_abnormal_embryonic_growth/wei1.63556224
40MP0003806_abnormal_nucleotide_metabolis1.61432467
41MP0002396_abnormal_hematopoietic_system1.59531369
42MP0010030_abnormal_orbit_morphology1.58859326
43MP0003786_premature_aging1.57448659
44MP0003119_abnormal_digestive_system1.56816956
45MP0003763_abnormal_thymus_physiology1.50739657
46MP0000313_abnormal_cell_death1.48029019
47MP0001293_anophthalmia1.42447290
48MP0006035_abnormal_mitochondrial_morpho1.35854592
49MP0003941_abnormal_skin_development1.34125014
50MP0002019_abnormal_tumor_incidence1.32044850
51MP0003283_abnormal_digestive_organ1.31942393
52MP0002111_abnormal_tail_morphology1.28334095
53MP0005083_abnormal_biliary_tract1.26043188
54MP0002877_abnormal_melanocyte_morpholog1.25797949
55MP0002166_altered_tumor_susceptibility1.25651054
56MP0008770_decreased_survivor_rate1.25390966
57MP0002163_abnormal_gland_morphology1.24286109
58MP0004808_abnormal_hematopoietic_stem1.22592544
59MP0000537_abnormal_urethra_morphology1.19365270
60MP0002132_abnormal_respiratory_system1.17974143
61MP0002653_abnormal_ependyma_morphology1.10528732
62MP0005220_abnormal_exocrine_pancreas1.09014030
63MP0002006_tumorigenesis1.08541569
64MP0001915_intracranial_hemorrhage1.08287615
65MP0004233_abnormal_muscle_weight1.06532007
66MP0009672_abnormal_birth_weight1.04766016
67MP0003937_abnormal_limbs/digits/tail_de1.04074983
68MP0003567_abnormal_fetal_cardiomyocyte1.04021438
69MP0009053_abnormal_anal_canal1.02611107
70MP0000703_abnormal_thymus_morphology1.01702590
71MP0009703_decreased_birth_body1.00546899
72MP0002722_abnormal_immune_system0.99107076
73MP0003315_abnormal_perineum_morphology0.96020934
74MP0003878_abnormal_ear_physiology0.92035663
75MP0005377_hearing/vestibular/ear_phenot0.92035663
76MP0009379_abnormal_foot_pigmentation0.90855840
77MP0003566_abnormal_cell_adhesion0.90005694
78MP0002210_abnormal_sex_determination0.89012767
79MP0002697_abnormal_eye_size0.88880030
80MP0000689_abnormal_spleen_morphology0.88212510
81MP0002925_abnormal_cardiovascular_devel0.88196586
82MP0001346_abnormal_lacrimal_gland0.88096176
83MP0003718_maternal_effect0.88035241
84MP0002092_abnormal_eye_morphology0.86307444
85MP0002398_abnormal_bone_marrow0.86224500
86MP0005501_abnormal_skin_physiology0.85523270
87MP0005171_absent_coat_pigmentation0.85419552
88MP0009278_abnormal_bone_marrow0.85312331
89MP0010234_abnormal_vibrissa_follicle0.84334591
90MP0005384_cellular_phenotype0.84249097
91MP0001849_ear_inflammation0.83834733
92MP0001145_abnormal_male_reproductive0.83776855
93MP0005621_abnormal_cell_physiology0.82359076
94MP0000015_abnormal_ear_pigmentation0.81647861
95MP0001986_abnormal_taste_sensitivity0.80562190
96MP0003861_abnormal_nervous_system0.80191331
97MP0006054_spinal_hemorrhage0.80109530
98MP0001727_abnormal_embryo_implantation0.79490847
99MP0004264_abnormal_extraembryonic_tissu0.78612721
100MP0001286_abnormal_eye_development0.75394703
101MP0005023_abnormal_wound_healing0.75164701
102MP0008995_early_reproductive_senescence0.73565661
103MP0001929_abnormal_gametogenesis0.70941080
104MP0000428_abnormal_craniofacial_morphol0.70366076
105MP0000003_abnormal_adipose_tissue0.70303525
106MP0000432_abnormal_head_morphology0.70269269
107MP0003385_abnormal_body_wall0.69754314
108MP0005623_abnormal_meninges_morphology0.69400651
109MP0000266_abnormal_heart_morphology0.68956435
110MP0002160_abnormal_reproductive_system0.68357394
111MP0003699_abnormal_female_reproductive0.67779719
112MP0002098_abnormal_vibrissa_morphology0.67746374
113MP0000653_abnormal_sex_gland0.67374321
114MP0003787_abnormal_imprinting0.66453009
115MP0000358_abnormal_cell_content/0.65758558
116MP0010678_abnormal_skin_adnexa0.64145527
117MP0009931_abnormal_skin_appearance0.63976271
118MP0005451_abnormal_body_composition0.63690371
119MP0000477_abnormal_intestine_morphology0.63585184
120MP0001119_abnormal_female_reproductive0.63238710
121MP0002060_abnormal_skin_morphology0.63220651
122MP0000733_abnormal_muscle_development0.62771962
123MP0009333_abnormal_splenocyte_physiolog0.62040693
124MP0003115_abnormal_respiratory_system0.61244841
125MP0002429_abnormal_blood_cell0.60702346
126MP0005389_reproductive_system_phenotype0.60139816
127MP0000013_abnormal_adipose_tissue0.58293800
128MP0001216_abnormal_epidermal_layer0.58202962
129MP0001873_stomach_inflammation0.57747948
130MP0005645_abnormal_hypothalamus_physiol0.55967814
131MP0001191_abnormal_skin_condition0.54906327
132MP0003935_abnormal_craniofacial_develop0.54815010
133MP0005266_abnormal_metabolism0.53369904
134MP0000747_muscle_weakness0.53277034

Predicted human phenotypes

RankGene SetZ-score
1Poikilocytosis (HP:0004447)5.89799938
2Abnormality of the heme biosynthetic pathway (HP:0010472)5.54520350
3Acanthocytosis (HP:0001927)4.72992586
4Reticulocytosis (HP:0001923)4.66310494
5Abnormality of reticulocytes (HP:0004312)4.19367728
6IgA deficiency (HP:0002720)4.06325317
7Birth length less than 3rd percentile (HP:0003561)4.06051158
8IgM deficiency (HP:0002850)4.03593916
9Chromsome breakage (HP:0040012)3.56641604
10Chromosomal breakage induced by crosslinking agents (HP:0003221)3.55226450
11Colitis (HP:0002583)3.52314122
12Microvesicular hepatic steatosis (HP:0001414)3.49868792
13Abnormality of cells of the erythroid lineage (HP:0012130)3.48530040
14Ependymoma (HP:0002888)3.46567893
15Reticulocytopenia (HP:0001896)3.35913921
16Abnormal number of erythroid precursors (HP:0012131)3.26112411
17Impulsivity (HP:0100710)3.22745710
18Selective tooth agenesis (HP:0001592)3.19580569
19Medulloblastoma (HP:0002885)3.13801253
20Hypochromic microcytic anemia (HP:0004840)3.03378958
21Aplasia/Hypoplasia of the sacrum (HP:0008517)3.02866550
22Absent radius (HP:0003974)3.00801688
23Short middle phalanx of the 5th finger (HP:0004220)3.00461725
24Breast hypoplasia (HP:0003187)2.93238686
25Abnormality of chromosome stability (HP:0003220)2.86440594
26Patellar aplasia (HP:0006443)2.85019299
27Abnormality of the labia minora (HP:0012880)2.83354848
28Aplasia involving forearm bones (HP:0009822)2.80047419
29Absent forearm bone (HP:0003953)2.80047419
30Nephroblastoma (Wilms tumor) (HP:0002667)2.76433372
31Clubbing of toes (HP:0100760)2.75595821
32Absent thumb (HP:0009777)2.74582144
33Colon cancer (HP:0003003)2.71707090
34Small intestinal stenosis (HP:0012848)2.71675169
35Duodenal stenosis (HP:0100867)2.71675169
36Aplasia/Hypoplasia of the patella (HP:0006498)2.64160906
37Abnormality of DNA repair (HP:0003254)2.62628234
38Macrocytic anemia (HP:0001972)2.62000259
39Meckel diverticulum (HP:0002245)2.59285763
40Progressive external ophthalmoplegia (HP:0000590)2.56906284
41Basal cell carcinoma (HP:0002671)2.54380517
42Embryonal renal neoplasm (HP:0011794)2.54129037
43Agnosia (HP:0010524)2.53436097
44Aplasia/Hypoplasia of the uvula (HP:0010293)2.52423420
45Astrocytoma (HP:0009592)2.49789166
46Abnormality of the astrocytes (HP:0100707)2.49789166
47Abnormality of the ileum (HP:0001549)2.48022808
48Pallor (HP:0000980)2.45786792
49Rib fusion (HP:0000902)2.45072297
50Carpal bone hypoplasia (HP:0001498)2.44116221
51Abnormality of pyrimidine metabolism (HP:0004353)2.41676465
52Abnormal number of incisors (HP:0011064)2.41409591
53Short 4th metacarpal (HP:0010044)2.40475278
54Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.40475278
55Rhabdomyosarcoma (HP:0002859)2.40023359
56Abnormality of abdominal situs (HP:0011620)2.39469337
57Abdominal situs inversus (HP:0003363)2.39469337
58Aplasia/hypoplasia of the humerus (HP:0006507)2.38779464
5911 pairs of ribs (HP:0000878)2.37533640
60Neoplasm of the oral cavity (HP:0100649)2.37368222
61Abnormality of the duodenum (HP:0002246)2.35852202
62Broad palm (HP:0001169)2.35768041
63Cafe-au-lait spot (HP:0000957)2.33796732
64Osteomalacia (HP:0002749)2.32528527
65Progressive muscle weakness (HP:0003323)2.30811197
66Ectopic kidney (HP:0000086)2.27907560
67Abnormality of the preputium (HP:0100587)2.27626813
68Short humerus (HP:0005792)2.26765352
69Supernumerary spleens (HP:0009799)2.25478191
70Missing ribs (HP:0000921)2.24221216
71Short 5th finger (HP:0009237)2.24132398
72Glioma (HP:0009733)2.21502929
73High pitched voice (HP:0001620)2.21134583
74Insomnia (HP:0100785)2.20564506
75Abnormality of the renal collecting system (HP:0004742)2.20120291
76Duplication of thumb phalanx (HP:0009942)2.18514576
77Abnormality of cochlea (HP:0000375)2.18042994
78Ureteral duplication (HP:0000073)2.17464771
79Hypergonadotropic hypogonadism (HP:0000815)2.17262953
80Deviation of the thumb (HP:0009603)2.15278596
81Myelodysplasia (HP:0002863)2.14900964
82Petechiae (HP:0000967)2.10739344
83Hypoplasia of the pons (HP:0012110)2.09403975
84Arteriovenous malformation (HP:0100026)2.09108742
85Cellulitis (HP:0100658)2.07848792
86Hyperacusis (HP:0010780)2.07263031
87Atresia of the external auditory canal (HP:0000413)2.06810014
88High anterior hairline (HP:0009890)2.05987464
89Degeneration of anterior horn cells (HP:0002398)2.05294787
90Abnormality of the anterior horn cell (HP:0006802)2.05294787
91Bone marrow hypocellularity (HP:0005528)2.04584674
92Proximal placement of thumb (HP:0009623)2.04260792
93Sandal gap (HP:0001852)2.01852193
94Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)2.01590394
95Prominent nose (HP:0000448)2.01356196
96Neoplasm of the pancreas (HP:0002894)2.01298447
97Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.98804090
98Abnormality of the parietal bone (HP:0002696)1.97588176
99Neoplasm of striated muscle (HP:0009728)1.96887376
100Sloping forehead (HP:0000340)1.96784559
101Asplenia (HP:0001746)1.96681648
102Microtia (HP:0008551)1.96542458
103Aplasia/Hypoplasia of the sternum (HP:0006714)1.94460961
104Short thumb (HP:0009778)1.93435104
105Increased density of long bones (HP:0006392)1.93355318
106Squamous cell carcinoma (HP:0002860)1.93044790
107Poikiloderma (HP:0001029)1.92613904
108Orthostatic hypotension (HP:0001278)1.91243094
109Abnormality of the pons (HP:0007361)1.90153707
110Abnormal lung lobation (HP:0002101)1.89925433
111Increased nuchal translucency (HP:0010880)1.89658401
112Skin tags (HP:0010609)1.88995126
113Acute lymphatic leukemia (HP:0006721)1.88552433
114Rectal fistula (HP:0100590)1.85914023
115Rectovaginal fistula (HP:0000143)1.85914023
116Hypochromic anemia (HP:0001931)1.85710718
117Spastic diplegia (HP:0001264)1.85250065
118Preauricular skin tag (HP:0000384)1.84102353
119Biliary tract neoplasm (HP:0100574)1.84098611
120Cholelithiasis (HP:0001081)1.83784917
121B lymphocytopenia (HP:0010976)1.83503456
122Breast aplasia (HP:0100783)1.83204915
123Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.82457107
124Duplicated collecting system (HP:0000081)1.81835102
125Anal stenosis (HP:0002025)1.81787666
126Thyroiditis (HP:0100646)1.81526166
127Abnormality of the carotid arteries (HP:0005344)1.81430643
128Long eyelashes (HP:0000527)1.81423280
129Malignant gastrointestinal tract tumors (HP:0006749)1.80643972
130Gastrointestinal carcinoma (HP:0002672)1.80643972
131Entropion (HP:0000621)1.80334180
132Embryonal neoplasm (HP:0002898)1.79793034
133Cutaneous photosensitivity (HP:0000992)1.79281060
134Oral leukoplakia (HP:0002745)1.78207754
135Horseshoe kidney (HP:0000085)1.76841749
136Rough bone trabeculation (HP:0100670)1.76034802
137Prostate neoplasm (HP:0100787)1.76000983
138Rectal prolapse (HP:0002035)1.75806232
139Renovascular hypertension (HP:0100817)1.74850008
140Ragged-red muscle fibers (HP:0003200)1.74308655
141Multiple enchondromatosis (HP:0005701)1.73898563
142Tracheoesophageal fistula (HP:0002575)1.73781485
143Inflammation of the large intestine (HP:0002037)1.73060261
144Uterine leiomyosarcoma (HP:0002891)1.73035524
145Leiomyosarcoma (HP:0100243)1.73035524
146Broad distal phalanx of finger (HP:0009836)1.71977390
147Sensory axonal neuropathy (HP:0003390)1.70422869
148Ankyloglossia (HP:0010296)1.70032490
149Triphalangeal thumb (HP:0001199)1.66968839
150Septate vagina (HP:0001153)1.66891086
151Neoplasm of the colon (HP:0100273)1.66771783
152Abnormality of chromosome segregation (HP:0002916)1.66227492

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TLK17.39088205
2ZAK4.80569932
3CDC73.96177526
4STK43.30098325
5VRK13.09260520
6BUB12.87003770
7CDK122.76582993
8RPS6KA52.57852571
9WEE12.44017436
10MAP3K102.37096287
11NEK22.34756978
12EIF2AK12.02666218
13MAP3K81.92605529
14SCYL21.89946944
15TTK1.88501208
16RPS6KB21.84701642
17EEF2K1.84286707
18EPHA21.82516897
19CHEK21.82408986
20AURKB1.75325348
21SRPK11.72975540
22DYRK31.66213734
23PLK11.50483243
24PBK1.45658195
25CDK91.44684607
26SMG11.44319248
27PIM11.44162830
28AURKA1.42398264
29TESK21.39307369
30NEK11.35890892
31TRIB31.34036785
32ATR1.33721505
33PLK41.27656014
34PKN21.23210990
35CDK71.16828515
36STK101.15881660
37PASK1.11995335
38BRD41.10075821
39CDK41.09764581
40CHEK11.05894808
41CDK81.05688150
42MAPKAPK30.98299982
43GRK60.98120312
44TAF10.95108075
45DAPK30.95025570
46FLT30.88486754
47ATM0.88367975
48PLK30.87157563
49CDK20.85488480
50AKT20.84376032
51ACVR1B0.80686998
52NME20.79522051
53STK160.76521366
54PAK40.76252534
55MKNK10.73619055
56MKNK20.72051934
57BRSK10.71176022
58BRSK20.71088407
59CCNB10.70543855
60IRAK30.68739733
61CDK10.65951101
62TTN0.65118150
63ALK0.64800218
64MELK0.64366843
65MTOR0.61981391
66CDK60.61603265
67PRPF4B0.55724584
68TESK10.53088457
69PIM20.52772059
70EIF2AK30.51713341
71PAK10.51024798
72PRKCI0.50289620
73RPS6KA40.49472900
74MAP2K30.48822994
75LRRK20.48409506
76ICK0.46000811
77CAMK1D0.44553020
78TSSK60.44038387
79LATS20.43466563
80STK30.40505039
81CSNK2A20.39705677
82CSNK1D0.39496588
83TGFBR10.38351689
84PRKDC0.37865717
85DYRK1B0.37757901
86EIF2AK20.37295493
87MST1R0.35810179
88MAPK140.35090198
89MAP3K110.34577764
90KDR0.34206330
91AKT10.33810846
92BMX0.32617516
93CSNK1G30.32449958
94BRAF0.30990557
95CSNK1G10.30668455
96PRKAA10.30589024
97MAP2K70.30184316
98CSNK1A1L0.29439583
99PKN10.29349033
100RAF10.28891092
101CLK10.28885595
102CSNK2A10.25848568
103BTK0.25837463
104MAPK110.25822275
105RPS6KL10.25601358
106RPS6KC10.25601358
107MET0.23328017
108CAMK40.22894858
109RPS6KA10.22603924
110GSK3B0.22366868
111MAPK10.21627672
112MAP3K40.20577636
113RPS6KB10.19552015
114CSNK1E0.18672664
115MAP2K40.17665046
116PRKCQ0.17313892
117LATS10.16817425
118RPS6KA60.16703733
119ROCK10.15749503
120PAK20.15690166
121NEK90.14552958
122BLK0.14145476
123IRAK20.12581479
124MAP4K10.12282970
125JAK20.11868337
126PAK60.11383821
127CDK150.11048060
128MAPK90.10745967
129IRAK40.10617826
130BCKDK0.10087484
131CAMKK20.09234104
132ILK0.08914175
133MAPKAPK50.07375143
134ABL20.06671330
135MAP2K20.06525146

Predicted pathways (KEGG)

RankGene SetZ-score
1* Systemic lupus erythematosus_Homo sapiens_hsa053228.92268596
2* Alcoholism_Homo sapiens_hsa050344.99192395
3DNA replication_Homo sapiens_hsa030304.24903058
4Mismatch repair_Homo sapiens_hsa034303.64352719
5One carbon pool by folate_Homo sapiens_hsa006702.71844207
6Viral carcinogenesis_Homo sapiens_hsa052032.70762259
7Cell cycle_Homo sapiens_hsa041102.52577854
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.44343627
9Base excision repair_Homo sapiens_hsa034102.37741603
10Spliceosome_Homo sapiens_hsa030402.37708942
11Nucleotide excision repair_Homo sapiens_hsa034202.25422597
12RNA transport_Homo sapiens_hsa030132.24303700
13Homologous recombination_Homo sapiens_hsa034402.23562052
14Ribosome_Homo sapiens_hsa030102.21815820
15Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.10000611
16Fanconi anemia pathway_Homo sapiens_hsa034602.00082500
17Non-homologous end-joining_Homo sapiens_hsa034501.85018895
18mRNA surveillance pathway_Homo sapiens_hsa030151.54866897
19RNA polymerase_Homo sapiens_hsa030201.54752979
20Transcriptional misregulation in cancer_Homo sapiens_hsa052021.51440444
21Pyrimidine metabolism_Homo sapiens_hsa002401.47872621
22Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.42891857
23p53 signaling pathway_Homo sapiens_hsa041151.42020060
24RNA degradation_Homo sapiens_hsa030181.17803723
25Proteasome_Homo sapiens_hsa030501.04707833
26Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.92023510
27MicroRNAs in cancer_Homo sapiens_hsa052060.90284069
28Basal transcription factors_Homo sapiens_hsa030220.85752391
29Selenocompound metabolism_Homo sapiens_hsa004500.85259957
30Oocyte meiosis_Homo sapiens_hsa041140.84135250
31Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.79032508
32Cyanoamino acid metabolism_Homo sapiens_hsa004600.76403249
33Biosynthesis of amino acids_Homo sapiens_hsa012300.74845275
34Bladder cancer_Homo sapiens_hsa052190.74608433
35HTLV-I infection_Homo sapiens_hsa051660.72433320
36Lysine degradation_Homo sapiens_hsa003100.68174909
37Epstein-Barr virus infection_Homo sapiens_hsa051690.67500779
38Small cell lung cancer_Homo sapiens_hsa052220.65404899
39Purine metabolism_Homo sapiens_hsa002300.63923575
40Sulfur relay system_Homo sapiens_hsa041220.60156455
41Basal cell carcinoma_Homo sapiens_hsa052170.58859278
42Herpes simplex infection_Homo sapiens_hsa051680.56670122
43Hippo signaling pathway_Homo sapiens_hsa043900.55484763
44Chronic myeloid leukemia_Homo sapiens_hsa052200.55276161
45Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.52800350
46TGF-beta signaling pathway_Homo sapiens_hsa043500.52277755
47Vitamin B6 metabolism_Homo sapiens_hsa007500.52086612
48Pentose phosphate pathway_Homo sapiens_hsa000300.49993737
49N-Glycan biosynthesis_Homo sapiens_hsa005100.49804538
50Primary immunodeficiency_Homo sapiens_hsa053400.49745696
51Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.49353965
52Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.49258479
53Thyroid cancer_Homo sapiens_hsa052160.47441126
54Cysteine and methionine metabolism_Homo sapiens_hsa002700.47033934
55Non-small cell lung cancer_Homo sapiens_hsa052230.42222598
56Apoptosis_Homo sapiens_hsa042100.40825174
57Central carbon metabolism in cancer_Homo sapiens_hsa052300.40221726
58Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.38938962
59mTOR signaling pathway_Homo sapiens_hsa041500.38427242
60Drug metabolism - other enzymes_Homo sapiens_hsa009830.38178182
61Colorectal cancer_Homo sapiens_hsa052100.35640442
62B cell receptor signaling pathway_Homo sapiens_hsa046620.34240276
63Melanoma_Homo sapiens_hsa052180.34010754
64Folate biosynthesis_Homo sapiens_hsa007900.32385235
65Notch signaling pathway_Homo sapiens_hsa043300.31732995
66Hedgehog signaling pathway_Homo sapiens_hsa043400.31016924
67Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.30949599
68Galactose metabolism_Homo sapiens_hsa000520.30816141
69Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.30435410
70Pyruvate metabolism_Homo sapiens_hsa006200.29482615
71Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.28648239
72Hepatitis B_Homo sapiens_hsa051610.28421667
73Carbon metabolism_Homo sapiens_hsa012000.28234612
74Antigen processing and presentation_Homo sapiens_hsa046120.26341883
75Pathways in cancer_Homo sapiens_hsa052000.26242803
76Inositol phosphate metabolism_Homo sapiens_hsa005620.25902716
77Arginine biosynthesis_Homo sapiens_hsa002200.24803474
78HIF-1 signaling pathway_Homo sapiens_hsa040660.22878621
79Prostate cancer_Homo sapiens_hsa052150.22772425
80Adherens junction_Homo sapiens_hsa045200.22595035
81Pancreatic cancer_Homo sapiens_hsa052120.22314751
82Proteoglycans in cancer_Homo sapiens_hsa052050.21315602
83Intestinal immune network for IgA production_Homo sapiens_hsa046720.21236632
84Tight junction_Homo sapiens_hsa045300.20765915
85Glutathione metabolism_Homo sapiens_hsa004800.19643948
862-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.18591134
87Asthma_Homo sapiens_hsa053100.16865450
88Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.16607002
89FoxO signaling pathway_Homo sapiens_hsa040680.15902150
90Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.15819168
91Huntingtons disease_Homo sapiens_hsa050160.15537026
92Acute myeloid leukemia_Homo sapiens_hsa052210.14890945
93AMPK signaling pathway_Homo sapiens_hsa041520.14359303
94Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.13615598
95Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.13002067
96Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.12714565
97Wnt signaling pathway_Homo sapiens_hsa043100.11636483
98Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.11595569
99RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.11099753
100Thyroid hormone signaling pathway_Homo sapiens_hsa049190.10747538
101Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.10580742
102Glioma_Homo sapiens_hsa052140.10193165
103Hematopoietic cell lineage_Homo sapiens_hsa046400.10120039
104Endometrial cancer_Homo sapiens_hsa052130.09590731
105Sulfur metabolism_Homo sapiens_hsa009200.09340646
106Regulation of actin cytoskeleton_Homo sapiens_hsa048100.09237180
107Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.07754829
108Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.07599680
109Fructose and mannose metabolism_Homo sapiens_hsa000510.07565890
110Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.07059973
111Metabolic pathways_Homo sapiens_hsa011000.06348863
112PI3K-Akt signaling pathway_Homo sapiens_hsa041510.06034334
113ErbB signaling pathway_Homo sapiens_hsa040120.05677755
114Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.04747259
115Phosphatidylinositol signaling system_Homo sapiens_hsa040700.04311401
116Measles_Homo sapiens_hsa051620.03966290
117Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.03758323
118Longevity regulating pathway - mammal_Homo sapiens_hsa042110.03397230
119Legionellosis_Homo sapiens_hsa051340.02376450
120Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.00826865

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