

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | cytidine deamination (GO:0009972) | 8.47971507 |
| 2 | cytidine metabolic process (GO:0046087) | 8.47971507 |
| 3 | cytidine catabolic process (GO:0006216) | 8.47971507 |
| 4 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 7.20891937 |
| 5 | DNA deamination (GO:0045006) | 6.87589573 |
| 6 | innate immune response in mucosa (GO:0002227) | 6.61064508 |
| 7 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 6.31920980 |
| 8 | mucosal immune response (GO:0002385) | 5.47759239 |
| 9 | purine-containing compound salvage (GO:0043101) | 5.40142876 |
| 10 | DNA replication-dependent nucleosome assembly (GO:0006335) | 5.32224960 |
| 11 | DNA replication-dependent nucleosome organization (GO:0034723) | 5.32224960 |
| 12 | antibacterial humoral response (GO:0019731) | 5.19230649 |
| 13 | urate metabolic process (GO:0046415) | 4.97716395 |
| 14 | organ or tissue specific immune response (GO:0002251) | 4.94639176 |
| 15 | antimicrobial humoral response (GO:0019730) | 4.69151729 |
| 16 | activated T cell proliferation (GO:0050798) | 4.64921471 |
| 17 | production of molecular mediator involved in inflammatory response (GO:0002532) | 4.63742744 |
| 18 | response to interferon-beta (GO:0035456) | 4.52523197 |
| 19 | cytolysis (GO:0019835) | 4.49375565 |
| 20 | inner mitochondrial membrane organization (GO:0007007) | 4.25171807 |
| 21 | purine nucleotide salvage (GO:0032261) | 3.97566041 |
| 22 | dolichol-linked oligosaccharide biosynthetic process (GO:0006488) | 3.95195380 |
| 23 | nucleosome assembly (GO:0006334) | 3.85418958 |
| 24 | GDP-mannose metabolic process (GO:0019673) | 3.82583904 |
| 25 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.74646831 |
| 26 | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902235 | 3.67869915 |
| 27 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 3.63626027 |
| 28 | positive regulation of defense response to virus by host (GO:0002230) | 3.63366735 |
| 29 | NAD biosynthetic process (GO:0009435) | 3.60138053 |
| 30 | protein-DNA complex assembly (GO:0065004) | 3.58475994 |
| 31 | negative regulation of viral genome replication (GO:0045071) | 3.58005932 |
| 32 | ATP synthesis coupled proton transport (GO:0015986) | 3.51460696 |
| 33 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.51460696 |
| 34 | nucleotide-sugar biosynthetic process (GO:0009226) | 3.47731015 |
| 35 | IMP biosynthetic process (GO:0006188) | 3.36457623 |
| 36 | mannosylation (GO:0097502) | 3.34668401 |
| 37 | lipoxygenase pathway (GO:0019372) | 3.33822416 |
| 38 | viral mRNA export from host cell nucleus (GO:0046784) | 3.30819330 |
| 39 | defense response to Gram-positive bacterium (GO:0050830) | 3.26118832 |
| 40 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.23191163 |
| 41 | DNA demethylation (GO:0080111) | 3.21643670 |
| 42 | GMP metabolic process (GO:0046037) | 3.18933425 |
| 43 | pyrimidine nucleoside catabolic process (GO:0046135) | 3.16930501 |
| 44 | cell fate commitment involved in formation of primary germ layer (GO:0060795) | 3.16648342 |
| 45 | immunoglobulin mediated immune response (GO:0016064) | 3.16332118 |
| 46 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.13396465 |
| 47 | protein homotrimerization (GO:0070207) | 3.12006038 |
| 48 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.10777704 |
| 49 | nucleosome organization (GO:0034728) | 3.06971032 |
| 50 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.04303738 |
| 51 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.04303738 |
| 52 | NADH dehydrogenase complex assembly (GO:0010257) | 3.04303738 |
| 53 | N-acetylglucosamine metabolic process (GO:0006044) | 2.99940247 |
| 54 | positive regulation of interferon-alpha production (GO:0032727) | 2.97812865 |
| 55 | protein complex biogenesis (GO:0070271) | 2.97066759 |
| 56 | DNA dealkylation (GO:0035510) | 2.96390644 |
| 57 | negative regulation of release of cytochrome c from mitochondria (GO:0090201) | 2.95084132 |
| 58 | protein-DNA complex subunit organization (GO:0071824) | 2.94231514 |
| 59 | protein neddylation (GO:0045116) | 2.91724134 |
| 60 | protein maturation by protein folding (GO:0022417) | 2.91297892 |
| 61 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 2.86810122 |
| 62 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.85694570 |
| 63 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.85551256 |
| 64 | GTP biosynthetic process (GO:0006183) | 2.84937548 |
| 65 | positive regulation of B cell differentiation (GO:0045579) | 2.84601537 |
| 66 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.83960085 |
| 67 | cornea development in camera-type eye (GO:0061303) | 2.83404589 |
| 68 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.83028451 |
| 69 | leukotriene biosynthetic process (GO:0019370) | 2.82913351 |
| 70 | pyrimidine ribonucleoside metabolic process (GO:0046131) | 2.82381519 |
| 71 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.82293067 |
| 72 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 2.82190153 |
| 73 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.82125558 |
| 74 | chromatin assembly (GO:0031497) | 2.81552810 |
| 75 | positive regulation of alpha-beta T cell differentiation (GO:0046638) | 2.81276870 |
| 76 | cell wall macromolecule catabolic process (GO:0016998) | 2.79716887 |
| 77 | negative regulation of ligase activity (GO:0051352) | 2.77818908 |
| 78 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.77818908 |
| 79 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.77082085 |
| 80 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.77082085 |
| 81 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.76718585 |
| 82 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.76648778 |
| 83 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.75755600 |
| 84 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.75359342 |
| 85 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.75359342 |
| 86 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.75359342 |
| 87 | regulation of interferon-alpha production (GO:0032647) | 2.74264948 |
| 88 | ncRNA 3-end processing (GO:0043628) | 2.73690141 |
| 89 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.73673937 |
| 90 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.73673937 |
| 91 | purine nucleobase biosynthetic process (GO:0009113) | 2.72650767 |
| 92 | lysine metabolic process (GO:0006553) | 2.71837170 |
| 93 | lysine catabolic process (GO:0006554) | 2.71837170 |
| 94 | purine nucleobase metabolic process (GO:0006144) | 2.69834532 |
| 95 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.67608177 |
| 96 | histone mRNA metabolic process (GO:0008334) | 2.66102284 |
| 97 | RNA destabilization (GO:0050779) | 2.65617094 |
| 98 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.64155190 |
| 99 | pyridine nucleotide biosynthetic process (GO:0019363) | 2.63619635 |
| 100 | nicotinamide nucleotide biosynthetic process (GO:0019359) | 2.63619635 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 8.17946957 |
| 2 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 6.42700022 |
| 3 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 4.17840749 |
| 4 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.86432261 |
| 5 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.38759546 |
| 6 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.16084645 |
| 7 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.91027835 |
| 8 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.78135534 |
| 9 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.75112973 |
| 10 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 2.54607585 |
| 11 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.48787046 |
| 12 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.33662300 |
| 13 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.31970911 |
| 14 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 2.30689171 |
| 15 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.29403839 |
| 16 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 2.24738392 |
| 17 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.24060792 |
| 18 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 2.22854504 |
| 19 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.21507035 |
| 20 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.21068826 |
| 21 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.19866811 |
| 22 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.18357354 |
| 23 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.17505210 |
| 24 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.12565473 |
| 25 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 2.08844395 |
| 26 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.07457721 |
| 27 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 2.02290695 |
| 28 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.00162030 |
| 29 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.00023320 |
| 30 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.91991259 |
| 31 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.91029926 |
| 32 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.90578823 |
| 33 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.89180436 |
| 34 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.85191677 |
| 35 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.81258905 |
| 36 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.80571195 |
| 37 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.80347092 |
| 38 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.79135940 |
| 39 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.70905250 |
| 40 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.65981435 |
| 41 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.61400375 |
| 42 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.58984255 |
| 43 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.53180162 |
| 44 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.52413701 |
| 45 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.48290361 |
| 46 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.48169452 |
| 47 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.47321008 |
| 48 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.44885874 |
| 49 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.44725521 |
| 50 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.43873546 |
| 51 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.42659256 |
| 52 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.40444157 |
| 53 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.37154076 |
| 54 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.36525649 |
| 55 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.34630902 |
| 56 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.33847995 |
| 57 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.33477279 |
| 58 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.33436950 |
| 59 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.32821118 |
| 60 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.32654097 |
| 61 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.30440741 |
| 62 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.30190639 |
| 63 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.29101109 |
| 64 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.29029318 |
| 65 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.28136546 |
| 66 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.23229822 |
| 67 | MYB_26560356_Chip-Seq_TH2_Human | 1.23202297 |
| 68 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.21434778 |
| 69 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.20912020 |
| 70 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.20732340 |
| 71 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.18653896 |
| 72 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.18601666 |
| 73 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.18296114 |
| 74 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.17542306 |
| 75 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.16239389 |
| 76 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.15053131 |
| 77 | P300_27268052_Chip-Seq_Bcells_Human | 1.10496218 |
| 78 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.09291127 |
| 79 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.09004244 |
| 80 | SOX2_18692474_ChIP-Seq_MESCs_Mouse | 1.06851471 |
| 81 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.03608983 |
| 82 | ETS1_22383799_ChIP-Seq_G1ME_Mouse | 1.02069620 |
| 83 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.02013994 |
| 84 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.99766088 |
| 85 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.99378757 |
| 86 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.96623314 |
| 87 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.96381628 |
| 88 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.95522793 |
| 89 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.94413493 |
| 90 | AR_20517297_ChIP-Seq_VCAP_Human | 0.90812872 |
| 91 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.90266399 |
| 92 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.90266399 |
| 93 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.88799376 |
| 94 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.86028889 |
| 95 | GATA3_26560356_Chip-Seq_TH2_Human | 0.85528345 |
| 96 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.84954498 |
| 97 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.83428976 |
| 98 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.83191337 |
| 99 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.82776484 |
| 100 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.82734488 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.81727127 |
| 2 | MP0005360_urolithiasis | 3.83566290 |
| 3 | MP0003950_abnormal_plasma_membrane | 3.45012589 |
| 4 | MP0003763_abnormal_thymus_physiology | 3.40432228 |
| 5 | MP0008057_abnormal_DNA_replication | 3.20837028 |
| 6 | MP0001835_abnormal_antigen_presentation | 3.19666611 |
| 7 | MP0008058_abnormal_DNA_repair | 3.15493459 |
| 8 | MP0009780_abnormal_chondrocyte_physiolo | 3.03110816 |
| 9 | MP0002138_abnormal_hepatobiliary_system | 2.65394133 |
| 10 | MP0003436_decreased_susceptibility_to | 2.58092446 |
| 11 | MP0002090_abnormal_vision | 2.36298989 |
| 12 | MP0002254_reproductive_system_inflammat | 2.27714278 |
| 13 | MP0002876_abnormal_thyroid_physiology | 2.19078404 |
| 14 | MP0005000_abnormal_immune_tolerance | 2.17783513 |
| 15 | MP0009333_abnormal_splenocyte_physiolog | 2.16347691 |
| 16 | MP0002736_abnormal_nociception_after | 2.06888178 |
| 17 | MP0010094_abnormal_chromosome_stability | 2.03918966 |
| 18 | MP0005167_abnormal_blood-brain_barrier | 2.03271011 |
| 19 | MP0003111_abnormal_nucleus_morphology | 1.97099580 |
| 20 | MP0008877_abnormal_DNA_methylation | 1.94197668 |
| 21 | MP0002166_altered_tumor_susceptibility | 1.93796850 |
| 22 | MP0002420_abnormal_adaptive_immunity | 1.93762821 |
| 23 | MP0003724_increased_susceptibility_to | 1.92746754 |
| 24 | MP0001800_abnormal_humoral_immune | 1.91025464 |
| 25 | MP0002148_abnormal_hypersensitivity_rea | 1.90237775 |
| 26 | MP0005646_abnormal_pituitary_gland | 1.85643149 |
| 27 | MP0001819_abnormal_immune_cell | 1.84186644 |
| 28 | MP0000372_irregular_coat_pigmentation | 1.80856367 |
| 29 | MP0001529_abnormal_vocalization | 1.71485813 |
| 30 | MP0009785_altered_susceptibility_to | 1.67101056 |
| 31 | MP0005645_abnormal_hypothalamus_physiol | 1.64184585 |
| 32 | MP0002723_abnormal_immune_serum | 1.60443320 |
| 33 | MP0005410_abnormal_fertilization | 1.57868201 |
| 34 | MP0001533_abnormal_skeleton_physiology | 1.56119770 |
| 35 | MP0005387_immune_system_phenotype | 1.55082037 |
| 36 | MP0001790_abnormal_immune_system | 1.55082037 |
| 37 | MP0002419_abnormal_innate_immunity | 1.53756280 |
| 38 | MP0003866_abnormal_defecation | 1.51529909 |
| 39 | MP0008875_abnormal_xenobiotic_pharmacok | 1.47685862 |
| 40 | MP0006082_CNS_inflammation | 1.47672066 |
| 41 | MP0002452_abnormal_antigen_presenting | 1.46937219 |
| 42 | MP0002006_tumorigenesis | 1.46599474 |
| 43 | MP0002722_abnormal_immune_system | 1.45535047 |
| 44 | MP0005025_abnormal_response_to | 1.44734773 |
| 45 | MP0001968_abnormal_touch/_nociception | 1.44397806 |
| 46 | MP0000716_abnormal_immune_system | 1.39147442 |
| 47 | MP0001919_abnormal_reproductive_system | 1.37739344 |
| 48 | MP0000703_abnormal_thymus_morphology | 1.35870851 |
| 49 | MP0000685_abnormal_immune_system | 1.35708864 |
| 50 | MP0001346_abnormal_lacrimal_gland | 1.33880492 |
| 51 | MP0010155_abnormal_intestine_physiology | 1.33155279 |
| 52 | MP0001502_abnormal_circadian_rhythm | 1.32176191 |
| 53 | MP0001348_abnormal_lacrimal_gland | 1.31175652 |
| 54 | MP0002398_abnormal_bone_marrow | 1.30501923 |
| 55 | MP0004233_abnormal_muscle_weight | 1.26052633 |
| 56 | MP0002938_white_spotting | 1.24341788 |
| 57 | MP0000689_abnormal_spleen_morphology | 1.21268515 |
| 58 | MP0002429_abnormal_blood_cell | 1.16596721 |
| 59 | MP0000613_abnormal_salivary_gland | 1.15607164 |
| 60 | MP0006292_abnormal_olfactory_placode | 1.14804105 |
| 61 | MP0002277_abnormal_respiratory_mucosa | 1.06171174 |
| 62 | MP0003195_calcinosis | 1.05093315 |
| 63 | MP0000490_abnormal_crypts_of | 1.03683158 |
| 64 | MP0000747_muscle_weakness | 1.02121284 |
| 65 | MP0003786_premature_aging | 0.99443993 |
| 66 | MP0001764_abnormal_homeostasis | 0.98831975 |
| 67 | MP0009643_abnormal_urine_homeostasis | 0.95786497 |
| 68 | MP0002160_abnormal_reproductive_system | 0.95451494 |
| 69 | MP0001845_abnormal_inflammatory_respons | 0.94869329 |
| 70 | MP0005389_reproductive_system_phenotype | 0.92725265 |
| 71 | MP0008469_abnormal_protein_level | 0.92162796 |
| 72 | MP0006072_abnormal_retinal_apoptosis | 0.90822953 |
| 73 | MP0006035_abnormal_mitochondrial_morpho | 0.89916084 |
| 74 | MP0000358_abnormal_cell_content/ | 0.89002208 |
| 75 | MP0001853_heart_inflammation | 0.88471746 |
| 76 | MP0003693_abnormal_embryo_hatching | 0.88434398 |
| 77 | MP0005165_increased_susceptibility_to | 0.86273169 |
| 78 | MP0002210_abnormal_sex_determination | 0.84786768 |
| 79 | MP0000566_synostosis | 0.84615517 |
| 80 | MP0003806_abnormal_nucleotide_metabolis | 0.83787116 |
| 81 | MP0001873_stomach_inflammation | 0.83690730 |
| 82 | MP0009763_increased_sensitivity_to | 0.82602514 |
| 83 | MP0001145_abnormal_male_reproductive | 0.82266497 |
| 84 | MP0005390_skeleton_phenotype | 0.81777602 |
| 85 | MP0002909_abnormal_adrenal_gland | 0.80543736 |
| 86 | MP0005253_abnormal_eye_physiology | 0.79862784 |
| 87 | MP0005551_abnormal_eye_electrophysiolog | 0.78954696 |
| 88 | MP0004957_abnormal_blastocyst_morpholog | 0.78092332 |
| 89 | MP0000639_abnormal_adrenal_gland | 0.77319904 |
| 90 | MP0001501_abnormal_sleep_pattern | 0.76951814 |
| 91 | MP0005266_abnormal_metabolism | 0.75826430 |
| 92 | MP0001929_abnormal_gametogenesis | 0.74567932 |
| 93 | MP0008872_abnormal_physiological_respon | 0.74544640 |
| 94 | MP0000653_abnormal_sex_gland | 0.71625835 |
| 95 | MP0001905_abnormal_dopamine_level | 0.71025412 |
| 96 | MP0009764_decreased_sensitivity_to | 0.69725584 |
| 97 | MP0005464_abnormal_platelet_physiology | 0.69152657 |
| 98 | MP0009765_abnormal_xenobiotic_induced | 0.68988244 |
| 99 | MP0004147_increased_porphyrin_level | 0.68806852 |
| 100 | MP0005332_abnormal_amino_acid | 0.68424180 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Visual hallucinations (HP:0002367) | 7.41108263 |
| 2 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 7.36885372 |
| 3 | Spastic diplegia (HP:0001264) | 6.71343211 |
| 4 | Autoimmune hemolytic anemia (HP:0001890) | 6.57614536 |
| 5 | Autoimmune thrombocytopenia (HP:0001973) | 6.51843185 |
| 6 | Increased cerebral lipofuscin (HP:0011813) | 6.31949784 |
| 7 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 6.17793007 |
| 8 | Tetraparesis (HP:0002273) | 5.90246158 |
| 9 | Testicular atrophy (HP:0000029) | 5.65999350 |
| 10 | Abnormality of T cell physiology (HP:0011840) | 4.64300878 |
| 11 | Recurrent viral infections (HP:0004429) | 4.45422047 |
| 12 | Prostate neoplasm (HP:0100787) | 4.42200844 |
| 13 | Abnormality of T cells (HP:0002843) | 4.13926885 |
| 14 | Abnormality of the prostate (HP:0008775) | 4.09981325 |
| 15 | Recurrent cutaneous fungal infections (HP:0011370) | 3.96389263 |
| 16 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.96389263 |
| 17 | Panhypogammaglobulinemia (HP:0003139) | 3.87061173 |
| 18 | Dyschromatopsia (HP:0007641) | 3.72684934 |
| 19 | 3-Methylglutaconic aciduria (HP:0003535) | 3.29184563 |
| 20 | Opisthotonus (HP:0002179) | 3.21401772 |
| 21 | Abnormality of purine metabolism (HP:0004352) | 3.17118351 |
| 22 | Aplastic anemia (HP:0001915) | 2.86725849 |
| 23 | Central scotoma (HP:0000603) | 2.83820100 |
| 24 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.83444672 |
| 25 | Agammaglobulinemia (HP:0004432) | 2.79329515 |
| 26 | Acute necrotizing encephalopathy (HP:0006965) | 2.75043757 |
| 27 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.71849185 |
| 28 | T lymphocytopenia (HP:0005403) | 2.70211971 |
| 29 | Abnormality of male internal genitalia (HP:0000022) | 2.63446406 |
| 30 | Type I transferrin isoform profile (HP:0003642) | 2.63034429 |
| 31 | Recurrent fungal infections (HP:0002841) | 2.53938327 |
| 32 | Congenital, generalized hypertrichosis (HP:0004540) | 2.52475846 |
| 33 | Gout (HP:0001997) | 2.49088014 |
| 34 | Abnormality of lateral ventricle (HP:0030047) | 2.45605861 |
| 35 | Oral leukoplakia (HP:0002745) | 2.43975291 |
| 36 | Hypoproteinemia (HP:0003075) | 2.43851566 |
| 37 | Mitochondrial inheritance (HP:0001427) | 2.38737070 |
| 38 | Hypobetalipoproteinemia (HP:0003563) | 2.37708665 |
| 39 | Rimmed vacuoles (HP:0003805) | 2.34006668 |
| 40 | Parakeratosis (HP:0001036) | 2.32594838 |
| 41 | Increased CSF lactate (HP:0002490) | 2.31726278 |
| 42 | Abnormality of T cell number (HP:0011839) | 2.31312463 |
| 43 | Lymphopenia (HP:0001888) | 2.29043762 |
| 44 | Acute encephalopathy (HP:0006846) | 2.28843316 |
| 45 | Progressive sensorineural hearing impairment (HP:0000408) | 2.28713284 |
| 46 | Dysautonomia (HP:0002459) | 2.21682688 |
| 47 | Lymphoma (HP:0002665) | 2.21024492 |
| 48 | Encephalitis (HP:0002383) | 2.20628615 |
| 49 | Recurrent lower respiratory tract infections (HP:0002783) | 2.19673390 |
| 50 | Cerebral hypomyelination (HP:0006808) | 2.19289680 |
| 51 | Cerebral edema (HP:0002181) | 2.09231748 |
| 52 | Progressive macrocephaly (HP:0004481) | 2.05881834 |
| 53 | Hepatocellular necrosis (HP:0001404) | 2.05870997 |
| 54 | Abnormality of nucleobase metabolism (HP:0010932) | 2.00596444 |
| 55 | Abnormal protein glycosylation (HP:0012346) | 2.00201897 |
| 56 | Abnormal glycosylation (HP:0012345) | 2.00201897 |
| 57 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.00201897 |
| 58 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.00201897 |
| 59 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.96624562 |
| 60 | Abnormality of the nasal septum (HP:0000419) | 1.92962614 |
| 61 | IgG deficiency (HP:0004315) | 1.92090645 |
| 62 | Hypoplasia of the uterus (HP:0000013) | 1.91112641 |
| 63 | Sparse eyelashes (HP:0000653) | 1.87897087 |
| 64 | Dry hair (HP:0011359) | 1.87433087 |
| 65 | Skin rash (HP:0000988) | 1.86980620 |
| 66 | Amniotic constriction ring (HP:0009775) | 1.86892729 |
| 67 | Abnormality of placental membranes (HP:0011409) | 1.86892729 |
| 68 | Recurrent skin infections (HP:0001581) | 1.86246062 |
| 69 | Vasculitis (HP:0002633) | 1.84473286 |
| 70 | Nausea (HP:0002018) | 1.82601691 |
| 71 | Cerebral palsy (HP:0100021) | 1.81918201 |
| 72 | Rough bone trabeculation (HP:0100670) | 1.81173840 |
| 73 | Neutropenia (HP:0001875) | 1.76350572 |
| 74 | Severe combined immunodeficiency (HP:0004430) | 1.76336249 |
| 75 | Short clavicles (HP:0000894) | 1.76219198 |
| 76 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.74712817 |
| 77 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.74712817 |
| 78 | Hepatic necrosis (HP:0002605) | 1.74462250 |
| 79 | Pancytopenia (HP:0001876) | 1.73742710 |
| 80 | B lymphocytopenia (HP:0010976) | 1.71898483 |
| 81 | Steatorrhea (HP:0002570) | 1.71202660 |
| 82 | Congenital stationary night blindness (HP:0007642) | 1.71144059 |
| 83 | Lethargy (HP:0001254) | 1.64362808 |
| 84 | Pulmonary fibrosis (HP:0002206) | 1.63541587 |
| 85 | Meningitis (HP:0001287) | 1.63438816 |
| 86 | Combined immunodeficiency (HP:0005387) | 1.62454100 |
| 87 | Lactic acidosis (HP:0003128) | 1.62075469 |
| 88 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.61763220 |
| 89 | Increased serum lactate (HP:0002151) | 1.59615124 |
| 90 | Aplasia/Hypoplasia of the clavicles (HP:0006710) | 1.59043082 |
| 91 | Reduced antithrombin III activity (HP:0001976) | 1.56559265 |
| 92 | Humeroradial synostosis (HP:0003041) | 1.56024901 |
| 93 | Synostosis involving the elbow (HP:0003938) | 1.56024901 |
| 94 | Dicarboxylic aciduria (HP:0003215) | 1.55757241 |
| 95 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.55757241 |
| 96 | Ridged nail (HP:0001807) | 1.52530235 |
| 97 | Hepatosplenomegaly (HP:0001433) | 1.50008829 |
| 98 | Attenuation of retinal blood vessels (HP:0007843) | 1.49973937 |
| 99 | Decreased central vision (HP:0007663) | 1.49531527 |
| 100 | Hypoalbuminemia (HP:0003073) | 1.49376266 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TLK1 | 6.91172070 |
| 2 | ZAK | 6.18624054 |
| 3 | VRK1 | 4.21623093 |
| 4 | BMPR1B | 4.16705925 |
| 5 | BCKDK | 3.78380818 |
| 6 | TXK | 3.20415162 |
| 7 | MAP4K1 | 3.15770433 |
| 8 | BUB1 | 2.85275766 |
| 9 | CDK8 | 2.77161463 |
| 10 | NEK1 | 2.54828470 |
| 11 | VRK2 | 2.03078598 |
| 12 | RPS6KA5 | 1.76575082 |
| 13 | TESK2 | 1.74542804 |
| 14 | AURKA | 1.64709479 |
| 15 | DAPK3 | 1.63471982 |
| 16 | KDR | 1.59056164 |
| 17 | TGFBR1 | 1.56464111 |
| 18 | KIT | 1.52613603 |
| 19 | GRK1 | 1.48879045 |
| 20 | SMG1 | 1.35358635 |
| 21 | MAP4K2 | 1.25774338 |
| 22 | MAPKAPK3 | 1.13744301 |
| 23 | ADRBK2 | 1.11867335 |
| 24 | CDK9 | 1.08574672 |
| 25 | TAOK3 | 1.06086731 |
| 26 | MAP2K7 | 1.04267956 |
| 27 | CHEK2 | 1.02319501 |
| 28 | STK4 | 1.00738725 |
| 29 | MST1R | 0.96500870 |
| 30 | MET | 0.91415891 |
| 31 | BMPR2 | 0.89943404 |
| 32 | MAP3K11 | 0.87196849 |
| 33 | NME2 | 0.86952520 |
| 34 | LYN | 0.86768907 |
| 35 | GRK7 | 0.86489016 |
| 36 | RPS6KB2 | 0.86017526 |
| 37 | AURKB | 0.85511073 |
| 38 | SYK | 0.84661794 |
| 39 | ITK | 0.79531121 |
| 40 | WEE1 | 0.79159268 |
| 41 | EIF2AK3 | 0.73495306 |
| 42 | TAF1 | 0.73475644 |
| 43 | FES | 0.72785600 |
| 44 | TBK1 | 0.69157560 |
| 45 | BTK | 0.68391551 |
| 46 | IKBKB | 0.64051949 |
| 47 | RIPK4 | 0.63830983 |
| 48 | PLK2 | 0.60691505 |
| 49 | CAMK2D | 0.58575111 |
| 50 | MAPKAPK5 | 0.58388936 |
| 51 | PKN1 | 0.58087875 |
| 52 | PRKCD | 0.56900488 |
| 53 | JAK3 | 0.53374824 |
| 54 | TYRO3 | 0.50642918 |
| 55 | ABL2 | 0.50301869 |
| 56 | RPS6KB1 | 0.49479283 |
| 57 | GSK3A | 0.48393309 |
| 58 | CDC7 | 0.42969699 |
| 59 | TNK2 | 0.42323188 |
| 60 | ZAP70 | 0.41920693 |
| 61 | CSNK1A1L | 0.38870527 |
| 62 | CAMK2G | 0.37898593 |
| 63 | PRKCQ | 0.37442424 |
| 64 | CSNK1A1 | 0.35734512 |
| 65 | GRK5 | 0.34763394 |
| 66 | CSNK1G3 | 0.33855338 |
| 67 | TESK1 | 0.33723272 |
| 68 | EPHA4 | 0.33515084 |
| 69 | IKBKE | 0.33399133 |
| 70 | FLT3 | 0.33140815 |
| 71 | CSNK2A2 | 0.32494530 |
| 72 | PIM1 | 0.32283776 |
| 73 | EIF2AK2 | 0.31444571 |
| 74 | PNCK | 0.31216940 |
| 75 | PAK1 | 0.30856383 |
| 76 | CSK | 0.30468599 |
| 77 | LCK | 0.30372986 |
| 78 | PLK3 | 0.29443894 |
| 79 | PRKCB | 0.29199496 |
| 80 | CSNK2A1 | 0.28725440 |
| 81 | CSF1R | 0.27863607 |
| 82 | PLK1 | 0.27760964 |
| 83 | LRRK2 | 0.27604310 |
| 84 | IGF1R | 0.27530060 |
| 85 | CDK7 | 0.27513363 |
| 86 | AKT2 | 0.27053668 |
| 87 | ATR | 0.24353505 |
| 88 | PLK4 | 0.23191357 |
| 89 | ADRBK1 | 0.22878176 |
| 90 | FYN | 0.21551034 |
| 91 | DAPK1 | 0.19998007 |
| 92 | MAP2K2 | 0.19964116 |
| 93 | MYLK | 0.19931166 |
| 94 | EEF2K | 0.19162049 |
| 95 | PDK2 | 0.18290437 |
| 96 | MAPK9 | 0.18051670 |
| 97 | PRKCI | 0.17662554 |
| 98 | GRK6 | 0.17130582 |
| 99 | ATM | 0.17032098 |
| 100 | MAPK7 | 0.16194468 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 8.51952069 |
| 2 | Alcoholism_Homo sapiens_hsa05034 | 5.42244320 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 3.30330140 |
| 4 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.62857330 |
| 5 | Viral carcinogenesis_Homo sapiens_hsa05203 | 2.54256260 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 2.30030174 |
| 7 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.17108441 |
| 8 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.07390000 |
| 9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.00022233 |
| 10 | Asthma_Homo sapiens_hsa05310 | 1.92628020 |
| 11 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.81571433 |
| 12 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.79738196 |
| 13 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.77498610 |
| 14 | DNA replication_Homo sapiens_hsa03030 | 1.75157525 |
| 15 | Parkinsons disease_Homo sapiens_hsa05012 | 1.71812414 |
| 16 | Spliceosome_Homo sapiens_hsa03040 | 1.63746892 |
| 17 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.55515557 |
| 18 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.53086548 |
| 19 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.48130247 |
| 20 | Mismatch repair_Homo sapiens_hsa03430 | 1.42935139 |
| 21 | Ribosome_Homo sapiens_hsa03010 | 1.39709368 |
| 22 | RNA polymerase_Homo sapiens_hsa03020 | 1.38105886 |
| 23 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.30328530 |
| 24 | Huntingtons disease_Homo sapiens_hsa05016 | 1.27034853 |
| 25 | Alzheimers disease_Homo sapiens_hsa05010 | 1.08909313 |
| 26 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.07380324 |
| 27 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.03113984 |
| 28 | Homologous recombination_Homo sapiens_hsa03440 | 0.99328328 |
| 29 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.98389693 |
| 30 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.98363091 |
| 31 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.95252802 |
| 32 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.92718333 |
| 33 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.90655115 |
| 34 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.88921565 |
| 35 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.88829862 |
| 36 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.88161176 |
| 37 | Viral myocarditis_Homo sapiens_hsa05416 | 0.85044768 |
| 38 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.84830111 |
| 39 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.82014799 |
| 40 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.80801262 |
| 41 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.80223189 |
| 42 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.78003280 |
| 43 | Base excision repair_Homo sapiens_hsa03410 | 0.76074861 |
| 44 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.74915557 |
| 45 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.72887156 |
| 46 | RNA transport_Homo sapiens_hsa03013 | 0.72593469 |
| 47 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.71578499 |
| 48 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.71061058 |
| 49 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.69444570 |
| 50 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.68254992 |
| 51 | Protein export_Homo sapiens_hsa03060 | 0.66710872 |
| 52 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.66082072 |
| 53 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.61399024 |
| 54 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.60105727 |
| 55 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.59263009 |
| 56 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.58961500 |
| 57 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.58729382 |
| 58 | Purine metabolism_Homo sapiens_hsa00230 | 0.57675966 |
| 59 | Basal transcription factors_Homo sapiens_hsa03022 | 0.56265225 |
| 60 | RNA degradation_Homo sapiens_hsa03018 | 0.56182587 |
| 61 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.51967283 |
| 62 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.51828192 |
| 63 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.51709325 |
| 64 | Legionellosis_Homo sapiens_hsa05134 | 0.50199555 |
| 65 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.50144915 |
| 66 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.49564339 |
| 67 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.49255705 |
| 68 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.48172621 |
| 69 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.47069945 |
| 70 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.46524997 |
| 71 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.44995078 |
| 72 | Leishmaniasis_Homo sapiens_hsa05140 | 0.43485023 |
| 73 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.42971434 |
| 74 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.41356282 |
| 75 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.40745102 |
| 76 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.38204845 |
| 77 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.37374480 |
| 78 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.36400113 |
| 79 | Metabolic pathways_Homo sapiens_hsa01100 | 0.35845665 |
| 80 | HTLV-I infection_Homo sapiens_hsa05166 | 0.34120742 |
| 81 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.34036848 |
| 82 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.33453581 |
| 83 | Mineral absorption_Homo sapiens_hsa04978 | 0.32518844 |
| 84 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.31973639 |
| 85 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.30911581 |
| 86 | Phototransduction_Homo sapiens_hsa04744 | 0.30905667 |
| 87 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.30686175 |
| 88 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.30443154 |
| 89 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.29273445 |
| 90 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.27281424 |
| 91 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.27133689 |
| 92 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.26985029 |
| 93 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.26834642 |
| 94 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.25352236 |
| 95 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.24065502 |
| 96 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.22868932 |
| 97 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.21288495 |
| 98 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.20953524 |
| 99 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.20143419 |
| 100 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.18862712 |

