HIST1H3I

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA replication-dependent nucleosome assembly (GO:0006335)8.93721937
2DNA replication-dependent nucleosome organization (GO:0034723)8.93721937
3chromatin assembly (GO:0031497)8.25947887
4regulation of histone H3-K9 methylation (GO:0051570)7.62390121
5nucleosome assembly (GO:0006334)6.96778803
6nuclear pore complex assembly (GO:0051292)6.08778342
7nucleosome organization (GO:0034728)6.02507512
8nuclear pore organization (GO:0006999)5.97622564
9DNA unwinding involved in DNA replication (GO:0006268)5.95717091
10protein-DNA complex assembly (GO:0065004)5.88609314
11chromatin assembly or disassembly (GO:0006333)5.86132569
12protein localization to kinetochore (GO:0034501)5.63625805
13mitotic chromosome condensation (GO:0007076)5.46097263
14regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450915.39831302
15V(D)J recombination (GO:0033151)5.33288788
16protein-DNA complex subunit organization (GO:0071824)5.26470828
17antibacterial humoral response (GO:0019731)5.11876630
18sister chromatid segregation (GO:0000819)5.10028957
19innate immune response in mucosa (GO:0002227)4.89722781
20protein localization to chromosome, centromeric region (GO:0071459)4.79366263
21antimicrobial humoral response (GO:0019730)4.76136469
22pore complex assembly (GO:0046931)4.59238007
23mitotic sister chromatid segregation (GO:0000070)4.53417224
24folic acid-containing compound biosynthetic process (GO:0009396)4.46262686
25DNA replication initiation (GO:0006270)4.38557748
26regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.32077594
27negative regulation of histone methylation (GO:0031061)4.31435283
28chromatin remodeling at centromere (GO:0031055)4.25290803
29regulation of gene silencing (GO:0060968)4.24109217
30CENP-A containing nucleosome assembly (GO:0034080)4.21576448
31regulation of gene silencing by RNA (GO:0060966)4.09298755
32regulation of posttranscriptional gene silencing (GO:0060147)4.09298755
33regulation of gene silencing by miRNA (GO:0060964)4.09298755
34mitotic nuclear envelope disassembly (GO:0007077)4.08301110
35positive regulation of chromosome segregation (GO:0051984)4.08288576
36DNA duplex unwinding (GO:0032508)4.06816774
37DNA geometric change (GO:0032392)4.05144623
38positive regulation of mitotic sister chromatid separation (GO:1901970)3.99452729
39positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.99452729
40positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.99452729
41mitotic sister chromatid cohesion (GO:0007064)3.98664501
42membrane disassembly (GO:0030397)3.88498943
43nuclear envelope disassembly (GO:0051081)3.88498943
44DNA strand elongation involved in DNA replication (GO:0006271)3.88239151
45kinetochore organization (GO:0051383)3.83184145
46IMP biosynthetic process (GO:0006188)3.82489998
47DNA replication-independent nucleosome organization (GO:0034724)3.81859322
48DNA replication-independent nucleosome assembly (GO:0006336)3.81859322
49regulation of sister chromatid cohesion (GO:0007063)3.81253560
50pre-miRNA processing (GO:0031054)3.80234145
51DNA topological change (GO:0006265)3.80074237
52dosage compensation (GO:0007549)3.79777773
53regulation of centriole replication (GO:0046599)3.78116869
54chromosome condensation (GO:0030261)3.74878921
55mucosal immune response (GO:0002385)3.70753056
56translesion synthesis (GO:0019985)3.68784658
57protein K6-linked ubiquitination (GO:0085020)3.68227040
58DNA strand elongation (GO:0022616)3.66854503
59somatic diversification of immune receptors via germline recombination within a single locus (GO:0003.65652153
60somatic cell DNA recombination (GO:0016444)3.65652153
61regulation of megakaryocyte differentiation (GO:0045652)3.64537933
62positive regulation of histone methylation (GO:0031062)3.61139256
63mitotic recombination (GO:0006312)3.59786148
64regulation of translational fidelity (GO:0006450)3.57367124
65negative regulation of hematopoietic progenitor cell differentiation (GO:1901533)3.51793862
66organ or tissue specific immune response (GO:0002251)3.49941570
67regulation of centrosome cycle (GO:0046605)3.49817607
68histone exchange (GO:0043486)3.48574423
69telomere maintenance via semi-conservative replication (GO:0032201)3.48360493
70regulation of DNA endoreduplication (GO:0032875)3.41556499
71attachment of spindle microtubules to kinetochore (GO:0008608)3.38333317
72DNA conformation change (GO:0071103)3.37604313
73IMP metabolic process (GO:0046040)3.36818209
74double-strand break repair via nonhomologous end joining (GO:0006303)3.36456803
75non-recombinational repair (GO:0000726)3.36456803
76viral mRNA export from host cell nucleus (GO:0046784)3.35281871
77postreplication repair (GO:0006301)3.34293780
78regulation of chromosome segregation (GO:0051983)3.33033082
79negative regulation of chromosome segregation (GO:0051985)3.31409308
80DNA ligation (GO:0006266)3.31395772
81meiotic chromosome segregation (GO:0045132)3.31223529
82telomere maintenance (GO:0000723)3.30979521
83regulation of RNA export from nucleus (GO:0046831)3.30594262
84somatic diversification of immune receptors (GO:0002200)3.29751735
85telomere organization (GO:0032200)3.27924037
86regulation of spindle organization (GO:0090224)3.26960622
87defense response to Gram-positive bacterium (GO:0050830)3.25598649
88protein localization to chromosome (GO:0034502)3.24787812
89telomere maintenance via recombination (GO:0000722)3.23592043
90spindle checkpoint (GO:0031577)3.21860222
91negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.20711857
92negative regulation of mitotic sister chromatid segregation (GO:0033048)3.20711857
93negative regulation of mitotic sister chromatid separation (GO:2000816)3.20711857
94negative regulation of sister chromatid segregation (GO:0033046)3.20711857
95negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.20711857
96DNA packaging (GO:0006323)3.19869435
97mitotic metaphase plate congression (GO:0007080)3.18883092
98tongue development (GO:0043586)3.18115007
99T cell lineage commitment (GO:0002360)3.17439551
100regulation of mitotic metaphase/anaphase transition (GO:0030071)3.17013697
101regulation of centrosome duplication (GO:0010824)3.16375651
102ATP-dependent chromatin remodeling (GO:0043044)3.12698111
103metaphase plate congression (GO:0051310)3.12589804
104negative regulation of thymocyte apoptotic process (GO:0070244)3.11761809
105mitotic spindle assembly checkpoint (GO:0007094)3.10351804
106regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.08305152
107spindle assembly checkpoint (GO:0071173)3.06607020
108histone lysine demethylation (GO:0070076)3.06351362
109chromosome segregation (GO:0007059)3.05665257
110regulation of helicase activity (GO:0051095)3.05365487
111regulation of histone methylation (GO:0031060)3.04765048
112mitotic spindle checkpoint (GO:0071174)3.04418279
113negative regulation of DNA repair (GO:0045738)3.02614493
114protoporphyrinogen IX metabolic process (GO:0046501)3.01616123
115nucleotide-excision repair, DNA gap filling (GO:0006297)3.01332188
116microtubule depolymerization (GO:0007019)3.00693944
117mitotic DNA integrity checkpoint (GO:0044774)3.00279557
118regulation of mitotic spindle organization (GO:0060236)2.99450297
119regulation of sister chromatid segregation (GO:0033045)2.98923184
120regulation of mitotic sister chromatid separation (GO:0010965)2.98923184
121regulation of mitotic sister chromatid segregation (GO:0033047)2.98923184
122histone demethylation (GO:0016577)2.97779842
123regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.96950504
124DNA synthesis involved in DNA repair (GO:0000731)2.95729837
125somatic hypermutation of immunoglobulin genes (GO:0016446)2.95078793
126somatic diversification of immune receptors via somatic mutation (GO:0002566)2.95078793
127maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.91105596

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.01098053
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.74385324
3* E2F4_17652178_ChIP-ChIP_JURKAT_Human4.25765176
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse4.21276829
5* SMAD1_18555785_ChIP-Seq_MESCs_Mouse3.09932714
6HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.04878917
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.51921368
8* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.29665061
9* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.27648517
10E2F1_21310950_ChIP-Seq_MCF-7_Human2.13906939
11* SOX2_16153702_ChIP-ChIP_HESCs_Human2.06800028
12EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.00230615
13FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse15.8414670
14* EGR1_23403033_ChIP-Seq_LIVER_Mouse1.98466968
15NELFA_20434984_ChIP-Seq_ESCs_Mouse1.96221360
16MYC_18555785_ChIP-Seq_MESCs_Mouse1.93273593
17* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.83936984
18* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.67134418
19* RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.65751236
20* SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.62296580
21EGR1_19374776_ChIP-ChIP_THP-1_Human1.61954151
22SOX2_18555785_ChIP-Seq_MESCs_Mouse1.59701206
23IRF1_19129219_ChIP-ChIP_H3396_Human1.59473542
24ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.57100850
25* POU5F1_16153702_ChIP-ChIP_HESCs_Human1.56150350
26AR_21909140_ChIP-Seq_LNCAP_Human1.54118831
27MYC_19079543_ChIP-ChIP_MESCs_Mouse1.49035953
28KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.47030696
29* KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.45953237
30ESR1_15608294_ChIP-ChIP_MCF-7_Human1.45461130
31POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.45320835
32HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.41552745
33* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.40075002
34HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.38131365
35SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.28540178
36* CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.26870362
37KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.24542429
38SALL1_21062744_ChIP-ChIP_HESCs_Human1.23171393
39* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.21190422
40* NANOG_16153702_ChIP-ChIP_HESCs_Human1.19882830
41* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.19272115
42VDR_23849224_ChIP-Seq_CD4+_Human1.18122384
43TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.17392647
44MYC_22102868_ChIP-Seq_BL_Human1.13259647
45* POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.11257672
46* SOX2_18692474_ChIP-Seq_MESCs_Mouse1.10208043
47* TCF3_18692474_ChIP-Seq_MESCs_Mouse1.09894098
48ELK1_19687146_ChIP-ChIP_HELA_Human1.08775229
49ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.05557469
50NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.01280426
51STAT3_1855785_ChIP-Seq_MESCs_Mouse0.99019409
52VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.98717156
53MYC_18358816_ChIP-ChIP_MESCs_Mouse0.97163362
54POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.93363237
55* E2F1_18555785_ChIP-Seq_MESCs_Mouse0.90746655
56XRN2_22483619_ChIP-Seq_HELA_Human0.90204437
57* NANOG_18555785_ChIP-Seq_MESCs_Mouse0.89956578
58FOXP3_21729870_ChIP-Seq_TREG_Human0.88165314
59PADI4_21655091_ChIP-ChIP_MCF-7_Human0.87556134
60* IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.84955640
61MYCN_18555785_ChIP-Seq_MESCs_Mouse0.84091475
62* CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.83229150
63MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.83015141
64CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.82924745
65BRD4_27068464_Chip-Seq_AML-cells_Mouse0.82319747
66THAP11_20581084_ChIP-Seq_MESCs_Mouse0.79778741
67STAT4_19710469_ChIP-ChIP_TH1__Mouse0.79378138
68HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.79010376
69ETS1_22383799_ChIP-Seq_G1ME_Mouse0.77520580
70* ZFX_18555785_ChIP-Seq_MESCs_Mouse0.77418132
71DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.77218881
72YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.77038973
73CREB1_15753290_ChIP-ChIP_HEK293T_Human0.76417985
74VDR_21846776_ChIP-Seq_THP-1_Human0.75819414
75NOTCH1_21737748_ChIP-Seq_TLL_Human0.75585307
76RBPJ_22232070_ChIP-Seq_NCS_Mouse0.73682364
77MAF_26560356_Chip-Seq_TH1_Human0.71016970
78NANOG_21062744_ChIP-ChIP_HESCs_Human0.70358546
79RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.70106139
80GATA1_22025678_ChIP-Seq_K562_Human0.69980142
81STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.68671411
82* NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.68646503
83PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.68537106
84SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.68189424
85DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.65657528
86KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.65069863
87ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.64766920
88EST1_17652178_ChIP-ChIP_JURKAT_Human0.64373149
89SALL4_22934838_ChIP-ChIP_CD34+_Human0.64334321
90MYB_26560356_Chip-Seq_TH1_Human0.63195801
91PKCTHETA_26484144_Chip-Seq_BREAST_Human0.62874167
92* POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.62865915
93CIITA_25753668_ChIP-Seq_RAJI_Human0.62385468
94KDM5A_27292631_Chip-Seq_BREAST_Human0.62284711
95* SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.61147233
96MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.60118771
97MYC_18940864_ChIP-ChIP_HL60_Human0.59609338
98* TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.59205518
99ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.58959379
100TTF2_22483619_ChIP-Seq_HELA_Human0.58040450
101SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.57178490
102GATA2_22383799_ChIP-Seq_G1ME_Mouse0.56917020
103GATA1_19941826_ChIP-Seq_K562_Human0.54237165
104* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.54198544
105TP63_19390658_ChIP-ChIP_HaCaT_Human0.53771750
106TCF3_18692474_ChIP-Seq_MEFs_Mouse0.53617419
107* POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.53609091
108SOX9_26525672_Chip-Seq_HEART_Mouse0.53001209
109PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.52364577
110FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.52123790
111E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.51233542
112MYB_26560356_Chip-Seq_TH2_Human0.51210376
113GATA3_27048872_Chip-Seq_THYMUS_Human0.47487104
114ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.47240832
115UTX_26944678_Chip-Seq_JUKART_Human0.47240192
116SOX17_20123909_ChIP-Seq_XEN_Mouse0.46746510
117DCP1A_22483619_ChIP-Seq_HELA_Human0.45922728

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability4.89502955
2MP0003111_abnormal_nucleus_morphology4.22070290
3MP0010307_abnormal_tumor_latency3.90771277
4MP0003077_abnormal_cell_cycle3.75218500
5MP0003693_abnormal_embryo_hatching3.60305961
6MP0004957_abnormal_blastocyst_morpholog3.16159660
7MP0010352_gastrointestinal_tract_polyps3.14641269
8MP0008057_abnormal_DNA_replication2.98790983
9MP0003705_abnormal_hypodermis_morpholog2.83646669
10MP0003763_abnormal_thymus_physiology2.69947247
11MP0005645_abnormal_hypothalamus_physiol2.66690903
12MP0003123_paternal_imprinting2.65720978
13MP0009697_abnormal_copulation2.52287259
14MP0003121_genomic_imprinting2.44534371
15MP0000350_abnormal_cell_proliferation2.38653496
16MP0005076_abnormal_cell_differentiation2.34864016
17MP0001730_embryonic_growth_arrest2.31199662
18MP0008007_abnormal_cellular_replicative2.30217089
19MP0003656_abnormal_erythrocyte_physiolo2.26577544
20MP0008932_abnormal_embryonic_tissue2.23460325
21MP0000685_abnormal_immune_system2.20103276
22MP0008058_abnormal_DNA_repair2.19341958
23MP0004381_abnormal_hair_follicle2.12085152
24MP0004147_increased_porphyrin_level2.04281609
25MP0010234_abnormal_vibrissa_follicle2.03141574
26MP0004197_abnormal_fetal_growth/weight/1.97684350
27MP0003941_abnormal_skin_development1.92997189
28MP0002084_abnormal_developmental_patter1.85184664
29MP0001697_abnormal_embryo_size1.84773237
30MP0002086_abnormal_extraembryonic_tissu1.82497657
31MP0008877_abnormal_DNA_methylation1.81080866
32MP0001672_abnormal_embryogenesis/_devel1.79628282
33MP0005380_embryogenesis_phenotype1.79628282
34MP0004808_abnormal_hematopoietic_stem1.77773044
35MP0002085_abnormal_embryonic_tissue1.77451153
36MP0005671_abnormal_response_to1.62154951
37MP0002080_prenatal_lethality1.60767398
38MP0003984_embryonic_growth_retardation1.58667269
39MP0006054_spinal_hemorrhage1.57936855
40MP0002396_abnormal_hematopoietic_system1.57785528
41MP0002088_abnormal_embryonic_growth/wei1.56513701
42MP0000537_abnormal_urethra_morphology1.56241670
43MP0003937_abnormal_limbs/digits/tail_de1.47938051
44MP0000490_abnormal_crypts_of1.45079482
45MP0010030_abnormal_orbit_morphology1.43729632
46MP0000569_abnormal_digit_pigmentation1.42684103
47MP0003890_abnormal_embryonic-extraembry1.41289658
48MP0003786_premature_aging1.34615386
49MP0001835_abnormal_antigen_presentation1.33508775
50MP0002019_abnormal_tumor_incidence1.31785534
51MP0009053_abnormal_anal_canal1.29608449
52MP0003787_abnormal_imprinting1.29334067
53MP0001293_anophthalmia1.28493012
54MP0002009_preneoplasia1.27315957
55MP0000313_abnormal_cell_death1.26865927
56MP0001800_abnormal_humoral_immune1.26741754
57MP0005075_abnormal_melanosome_morpholog1.26351514
58MP0002138_abnormal_hepatobiliary_system1.25540049
59MP0000703_abnormal_thymus_morphology1.18078399
60MP0002111_abnormal_tail_morphology1.17962882
61MP0000733_abnormal_muscle_development1.17856102
62MP0001661_extended_life_span1.17344521
63MP0002092_abnormal_eye_morphology1.16341974
64MP0002254_reproductive_system_inflammat1.15216667
65MP0001915_intracranial_hemorrhage1.15031666
66MP0002697_abnormal_eye_size1.14950335
67MP0003567_abnormal_fetal_cardiomyocyte1.11755025
68MP0005623_abnormal_meninges_morphology1.11075388
69MP0009703_decreased_birth_body1.09856310
70MP0003119_abnormal_digestive_system1.03555968
71MP0000428_abnormal_craniofacial_morphol1.03474360
72MP0009672_abnormal_birth_weight1.03307642
73MP0008770_decreased_survivor_rate1.02695996
74MP0003283_abnormal_digestive_organ1.01758101
75MP0002722_abnormal_immune_system0.99761464
76MP0005310_abnormal_salivary_gland0.99255398
77MP0003566_abnormal_cell_adhesion0.99043378
78MP0005220_abnormal_exocrine_pancreas0.97725845
79MP0002877_abnormal_melanocyte_morpholog0.97419627
80MP0003718_maternal_effect0.93682859
81MP0002160_abnormal_reproductive_system0.93379736
82MP0002925_abnormal_cardiovascular_devel0.93283841
83MP0002398_abnormal_bone_marrow0.92869278
84MP0000716_abnormal_immune_system0.90557457
85MP0004185_abnormal_adipocyte_glucose0.90184563
86MP0000689_abnormal_spleen_morphology0.88808105
87MP0006035_abnormal_mitochondrial_morpho0.88194596
88MP0003861_abnormal_nervous_system0.87629289
89MP0008438_abnormal_cutaneous_collagen0.86453364
90MP0002166_altered_tumor_susceptibility0.85708113
91MP0003115_abnormal_respiratory_system0.85556465
92MP0005387_immune_system_phenotype0.85283889
93MP0001790_abnormal_immune_system0.85283889
94MP0000358_abnormal_cell_content/0.83521639
95MP0001286_abnormal_eye_development0.82873518
96MP0010678_abnormal_skin_adnexa0.81815621
97MP0005621_abnormal_cell_physiology0.80984628
98MP0001727_abnormal_embryo_implantation0.79549029
99MP0005384_cellular_phenotype0.79209807
100MP0005023_abnormal_wound_healing0.78935237
101MP0000432_abnormal_head_morphology0.78809933
102MP0003935_abnormal_craniofacial_develop0.75405513
103MP0005647_abnormal_sex_gland0.74160536
104MP0000631_abnormal_neuroendocrine_gland0.73684381
105MP0003300_gastrointestinal_ulcer0.73094526
106MP0002006_tumorigenesis0.72986982
107MP0001849_ear_inflammation0.70448306
108MP0009278_abnormal_bone_marrow0.70351366
109MP0004264_abnormal_extraembryonic_tissu0.70241489
110MP0002420_abnormal_adaptive_immunity0.69171049
111MP0003315_abnormal_perineum_morphology0.68866044
112MP0001119_abnormal_female_reproductive0.68654930
113MP0005397_hematopoietic_system_phenotyp0.68588728
114MP0001545_abnormal_hematopoietic_system0.68588728
115MP0005083_abnormal_biliary_tract0.68107448
116MP0003091_abnormal_cell_migration0.67929354
117MP0004947_skin_inflammation0.66547381
118MP0000266_abnormal_heart_morphology0.66084721
119MP0001819_abnormal_immune_cell0.65475614
120MP0004233_abnormal_muscle_weight0.64841433
121MP0002429_abnormal_blood_cell0.64297338
122MP0005000_abnormal_immune_tolerance0.64162791
123MP0003448_altered_tumor_morphology0.63304913
124MP0002405_respiratory_system_inflammati0.62908486
125MP0001929_abnormal_gametogenesis0.61739771
126MP0002452_abnormal_antigen_presenting0.61667116
127MP0006072_abnormal_retinal_apoptosis0.61504714
128MP0000477_abnormal_intestine_morphology0.60747151
129MP0005501_abnormal_skin_physiology0.60393192
130MP0001145_abnormal_male_reproductive0.59974200
131MP0002282_abnormal_trachea_morphology0.59973022
132MP0002210_abnormal_sex_determination0.57984002
133MP0005391_vision/eye_phenotype0.56827746
134MP0001784_abnormal_fluid_regulation0.56018536
135MP0005187_abnormal_penis_morphology0.54803029

Predicted human phenotypes

RankGene SetZ-score
1IgM deficiency (HP:0002850)5.51050432
2IgA deficiency (HP:0002720)5.07600969
3B lymphocytopenia (HP:0010976)4.93154587
4Abnormality of B cell number (HP:0010975)4.21633151
5Poikilocytosis (HP:0004447)4.09204719
6Colitis (HP:0002583)3.63601180
7Embryonal renal neoplasm (HP:0011794)3.58940098
8Short 4th metacarpal (HP:0010044)3.49171189
9Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.49171189
10Gastrointestinal stroma tumor (HP:0100723)3.40820286
11Combined immunodeficiency (HP:0005387)3.33676817
12Prostate neoplasm (HP:0100787)3.31820407
13Ependymoma (HP:0002888)3.30145195
14Severe combined immunodeficiency (HP:0004430)3.27145018
15Chromsome breakage (HP:0040012)3.25037256
16Chromosomal breakage induced by crosslinking agents (HP:0003221)3.21388279
17Medulloblastoma (HP:0002885)3.14685250
18Acanthocytosis (HP:0001927)3.12306728
19Abnormality of chromosome stability (HP:0003220)3.06185569
20Panhypogammaglobulinemia (HP:0003139)3.05009807
21Reticulocytopenia (HP:0001896)3.03997817
22Lymphopenia (HP:0001888)3.02489656
23Cutaneous melanoma (HP:0012056)3.02467349
24Hypochromic microcytic anemia (HP:0004840)3.01570023
25Abnormality of the astrocytes (HP:0100707)2.96015869
26Astrocytoma (HP:0009592)2.96015869
27Impulsivity (HP:0100710)2.91891094
28Volvulus (HP:0002580)2.87474265
29Selective tooth agenesis (HP:0001592)2.87395517
30Abnormality of reticulocytes (HP:0004312)2.86837201
31Agammaglobulinemia (HP:0004432)2.84095583
32Recurrent sinusitis (HP:0011108)2.83048661
33Abnormality of cells of the lymphoid lineage (HP:0012140)2.82496597
34Reticulocytosis (HP:0001923)2.77184355
35Lymphoma (HP:0002665)2.74274340
36Colon cancer (HP:0003003)2.70437225
37Abnormality of the labia minora (HP:0012880)2.69870962
38Abnormality of the heme biosynthetic pathway (HP:0010472)2.66365288
39Rhabdomyosarcoma (HP:0002859)2.62511777
40Recurrent viral infections (HP:0004429)2.61453408
41Clubbing of toes (HP:0100760)2.61146428
42Cellulitis (HP:0100658)2.59521670
43Agnosia (HP:0010524)2.59475831
44Acute lymphatic leukemia (HP:0006721)2.58140218
45Glioma (HP:0009733)2.57905505
46Increased nuchal translucency (HP:0010880)2.57881941
47Birth length less than 3rd percentile (HP:0003561)2.56637670
48Cafe-au-lait spot (HP:0000957)2.50102544
49Basal cell carcinoma (HP:0002671)2.49831747
50Sandal gap (HP:0001852)2.48297260
51Deviation of the thumb (HP:0009603)2.47385552
52Neoplasm of the adrenal cortex (HP:0100641)2.42121487
53High pitched voice (HP:0001620)2.41756680
54Hypoplasia of the thymus (HP:0000778)2.41401243
55Autoimmune hemolytic anemia (HP:0001890)2.40924485
56Abnormality of the 4th metacarpal (HP:0010012)2.39281754
57Abnormality of the prostate (HP:0008775)2.38151833
58Proximal placement of thumb (HP:0009623)2.37575318
59Dry hair (HP:0011359)2.33678719
60Embryonal neoplasm (HP:0002898)2.33157751
61IgG deficiency (HP:0004315)2.32030703
62Neoplasm of the oral cavity (HP:0100649)2.29902274
63Recurrent bronchitis (HP:0002837)2.28872465
64Ulnar bowing (HP:0003031)2.28130811
65Abnormality of cells of the erythroid lineage (HP:0012130)2.25410495
66Biliary tract neoplasm (HP:0100574)2.21918258
67Absent frontal sinuses (HP:0002688)2.21890581
68Leukopenia (HP:0001882)2.20909439
69Small intestinal stenosis (HP:0012848)2.18623463
70Duodenal stenosis (HP:0100867)2.18623463
71Cellular immunodeficiency (HP:0005374)2.18058481
72Aplasia/Hypoplasia of the uvula (HP:0010293)2.17653621
73Neoplasm of striated muscle (HP:0009728)2.15714495
74Prominent nose (HP:0000448)2.15233676
75Oral leukoplakia (HP:0002745)2.15207192
76Abnormality of the fingertips (HP:0001211)2.14338331
77Meckel diverticulum (HP:0002245)2.13277447
78Ectopic kidney (HP:0000086)2.11962518
79Renovascular hypertension (HP:0100817)2.10310951
80Insomnia (HP:0100785)2.09697411
81Malignant gastrointestinal tract tumors (HP:0006749)2.09162971
82Gastrointestinal carcinoma (HP:0002672)2.09162971
83Hypopigmentation of the fundus (HP:0007894)2.07899459
8411 pairs of ribs (HP:0000878)2.06261835
85Squamous cell carcinoma (HP:0002860)2.05804591
86Absent radius (HP:0003974)2.04226409
87Cortical dysplasia (HP:0002539)2.03774638
88Arteriovenous malformation (HP:0100026)2.03754462
89Abnormality of the ileum (HP:0001549)2.03674683
90Myelodysplasia (HP:0002863)2.03503451
91Missing ribs (HP:0000921)2.01385301
92Atresia of the external auditory canal (HP:0000413)2.00469242
93Ridged nail (HP:0001807)1.99952782
94Abnormal number of incisors (HP:0011064)1.99622883
95Heterotopia (HP:0002282)1.97410985
96Abnormality of chromosome segregation (HP:0002916)1.97166242
97Inflammation of the large intestine (HP:0002037)1.96161182
98Abnormality of the calcaneus (HP:0008364)1.96080496
99Abnormality of the parietal bone (HP:0002696)1.96077241
100Sloping forehead (HP:0000340)1.95181001
101Abnormality of the carotid arteries (HP:0005344)1.95005968
102High anterior hairline (HP:0009890)1.94430329
103Patellar aplasia (HP:0006443)1.93977399
104Abnormality of the duodenum (HP:0002246)1.91419928
105Short thumb (HP:0009778)1.91015547
106Anal stenosis (HP:0002025)1.90730266
107Renal duplication (HP:0000075)1.90662593
108Gastrointestinal inflammation (HP:0004386)1.89865296
109Aplasia/Hypoplasia of the sternum (HP:0006714)1.89445535
110Abnormal lung lobation (HP:0002101)1.88265977
111Aplasia involving forearm bones (HP:0009822)1.87130178
112Absent forearm bone (HP:0003953)1.87130178
113Freckling (HP:0001480)1.85899719
114Carpal bone hypoplasia (HP:0001498)1.85827655
115Meningitis (HP:0001287)1.84769162
116Absent thumb (HP:0009777)1.84636085
117Large earlobe (HP:0009748)1.83952914
118Abnormality of DNA repair (HP:0003254)1.83733393
119Macrocytic anemia (HP:0001972)1.83018090
120Skull defect (HP:0001362)1.82771947
121Amaurosis fugax (HP:0100576)1.81541943
122Bowel diverticulosis (HP:0005222)1.80547349
123Abnormality of the preputium (HP:0100587)1.80454127
124Viral hepatitis (HP:0006562)1.80327464
125Hyperacusis (HP:0010780)1.80047805
126Abnormal number of erythroid precursors (HP:0012131)1.78494816
127Ovarian neoplasm (HP:0100615)1.78372425
128Abnormality of abdominal situs (HP:0011620)1.77278409
129Abdominal situs inversus (HP:0003363)1.77278409
130Deep philtrum (HP:0002002)1.77241337
131Truncal obesity (HP:0001956)1.77228826
132Nephroblastoma (Wilms tumor) (HP:0002667)1.76741621
133Short humerus (HP:0005792)1.76582407
134Neoplasm of the pancreas (HP:0002894)1.75421428
135Hepatitis (HP:0012115)1.74976857
136Thyroiditis (HP:0100646)1.74836184
137Abnormality of the distal phalanx of the thumb (HP:0009617)1.74790972
138Aplasia/Hypoplasia of the patella (HP:0006498)1.74522859
139Tracheoesophageal fistula (HP:0002575)1.73986224
140Abnormality of oral frenula (HP:0000190)1.73758396
141Erythema (HP:0010783)1.73712456
142Skin tags (HP:0010609)1.73207471
143Long eyelashes (HP:0000527)1.73146132
144Ankyloglossia (HP:0010296)1.72781549
145Intestinal polyposis (HP:0200008)1.72557334
146Wrist flexion contracture (HP:0001239)1.72343698
147Spastic diplegia (HP:0001264)1.72089814
148Intestinal polyp (HP:0005266)1.71227017
149Chronic diarrhea (HP:0002028)1.70733013
150Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.70500045
151Onycholysis (HP:0001806)1.70263374
152Acute myeloid leukemia (HP:0004808)1.67588781
153Neoplasm of the heart (HP:0100544)1.63719048
154Bone marrow hypocellularity (HP:0005528)1.63382987
155T lymphocytopenia (HP:0005403)1.62181341
156Horseshoe kidney (HP:0000085)1.61438026
157Down-sloping shoulders (HP:0200021)1.59464507

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TLK19.18804452
2ZAK5.84683217
3CDC73.68170287
4VRK13.33464041
5STK43.09141802
6RPS6KA52.94007888
7MAP3K102.60622900
8TAF12.28629650
9SMG12.22257304
10EEF2K2.20475539
11CDK92.17952644
12SCYL22.01153615
13NEK22.00456072
14BUB11.89540407
15PKN21.71692485
16CHEK21.70268040
17AURKB1.70158780
18WEE11.65683331
19CDK121.65284103
20SRPK11.64798745
21MAP3K81.64773328
22PIM11.49203880
23RPS6KB21.44546802
24TTK1.32747731
25NLK1.24721985
26DAPK31.21903325
27TTN1.19850333
28EIF2AK11.15534409
29ATR1.14966316
30VRK21.14763271
31EPHA21.11327768
32PASK1.08708720
33DYRK31.08406146
34CDK41.06004770
35PLK11.05604860
36PKN10.99835306
37AURKA0.97438817
38FLT30.94932942
39NEK10.93839848
40STK100.90118472
41MELK0.85787474
42CHEK10.85630087
43GRK60.80243529
44ATM0.79480345
45PLK30.79445339
46ACVR1B0.77340430
47CDK60.74433604
48BTK0.70659909
49CAMK1D0.69677587
50CDK20.68871600
51BRAF0.65830080
52AKT20.63017206
53LRRK20.61643638
54CDK70.60761720
55CDK10.54606972
56TGFBR10.53794523
57FRK0.53620886
58BRSK20.52286298
59FGFR20.52270053
60NUAK10.52108309
61PBK0.51714741
62DYRK1B0.51492113
63KSR10.51279412
64NME20.50754879
65CSNK1D0.49796223
66CAMK40.48316758
67STK30.47004624
68BMPR1B0.45527740
69MTOR0.45067861
70CLK10.42404617
71CCNB10.39691902
72LATS10.39449253
73PAK40.39426684
74TRIB30.38780510
75SYK0.38157024
76BLK0.37946668
77PRKDC0.37565449
78BRD40.36396092
79ICK0.35334850
80NEK90.35313938
81PAK20.35207964
82PRKAA10.35187849
83CAMK1G0.35142275
84PTK60.34800585
85ALK0.34647677
86PDGFRA0.32510700
87EIF2AK30.31880587
88BRSK10.31076938
89PAK10.30898854
90RPS6KA40.30423778
91MKNK20.29911934
92EIF2AK20.29334604
93FGR0.28804941
94PLK40.27619353
95MKNK10.27472858
96ROCK10.26838554
97JAK20.26748125
98MAPK140.26630366
99MAP4K10.26220412
100MAP3K90.25887055
101RIPK10.23263328
102FGFR10.23027026
103AKT10.22832529
104MET0.22559100
105CSNK1G10.22191104
106RPS6KB10.21907757
107MAPK110.21722629
108MAP2K70.21251650
109CDK80.20888760
110PRPF4B0.20768276
111TRPM70.20544501
112TSSK60.20537512
113MAPKAPK50.20131972
114CSNK2A20.19973654
115MAP3K40.19947987
116BMX0.17338919
117TESK20.16699720
118CSNK1G30.15830657
119CSNK1A1L0.15501863
120STK240.15462592
121LYN0.15455180
122SGK10.14015739
123MAPK10.13501470
124RAF10.13410513
125RPS6KA30.13020098
126PRKCQ0.12902541
127PRKCI0.12862591
128RPS6KC10.12778995
129RPS6KL10.12778995
130GSK3B0.12720995
131PIK3CG0.12356271
132CSF1R0.11748237
133MST40.11373771
134SGK20.10933402
135HIPK20.10922317
136IRAK40.10890929
137TEC0.09739767
138BCKDK0.08905146
139MAPK90.05830827
140PRKCB0.05469811

Predicted pathways (KEGG)

RankGene SetZ-score
1* Alcoholism_Homo sapiens_hsa050346.48622584
2Viral carcinogenesis_Homo sapiens_hsa052033.40622600
3DNA replication_Homo sapiens_hsa030302.92656934
4Mismatch repair_Homo sapiens_hsa034302.51862045
5One carbon pool by folate_Homo sapiens_hsa006702.11188451
6Cell cycle_Homo sapiens_hsa041102.08818553
7* Systemic lupus erythematosus_Homo sapiens_hsa0532211.3733889
8* Transcriptional misregulation in cancer_Homo sapiens_hsa052021.79777611
9Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.69828863
10RNA transport_Homo sapiens_hsa030131.62617532
11Nucleotide excision repair_Homo sapiens_hsa034201.55418812
12Primary immunodeficiency_Homo sapiens_hsa053401.54084711
13Non-homologous end-joining_Homo sapiens_hsa034501.52073683
14Fanconi anemia pathway_Homo sapiens_hsa034601.48769851
15Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.47429460
16Homologous recombination_Homo sapiens_hsa034401.44003949
17Base excision repair_Homo sapiens_hsa034101.42487279
18Spliceosome_Homo sapiens_hsa030401.42066448
19Intestinal immune network for IgA production_Homo sapiens_hsa046721.18247495
20Ribosome_Homo sapiens_hsa030101.16960190
21p53 signaling pathway_Homo sapiens_hsa041151.06431213
22mRNA surveillance pathway_Homo sapiens_hsa030151.04813719
23MicroRNAs in cancer_Homo sapiens_hsa052061.04311277
24Asthma_Homo sapiens_hsa053100.92323492
25Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.89546319
26Allograft rejection_Homo sapiens_hsa053300.84433152
27Small cell lung cancer_Homo sapiens_hsa052220.82771424
28Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.81259412
29Autoimmune thyroid disease_Homo sapiens_hsa053200.80037939
30Chronic myeloid leukemia_Homo sapiens_hsa052200.74124928
31Selenocompound metabolism_Homo sapiens_hsa004500.71763550
32Pyrimidine metabolism_Homo sapiens_hsa002400.70314750
33RNA degradation_Homo sapiens_hsa030180.70060521
34Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.69548416
35HTLV-I infection_Homo sapiens_hsa051660.68293738
36Oocyte meiosis_Homo sapiens_hsa041140.66662019
37Graft-versus-host disease_Homo sapiens_hsa053320.65647844
38Non-small cell lung cancer_Homo sapiens_hsa052230.62695364
39Bladder cancer_Homo sapiens_hsa052190.61667902
40mTOR signaling pathway_Homo sapiens_hsa041500.53927800
41Type I diabetes mellitus_Homo sapiens_hsa049400.53047258
42Lysine degradation_Homo sapiens_hsa003100.52504426
43Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.49833306
44Epstein-Barr virus infection_Homo sapiens_hsa051690.49165967
45RNA polymerase_Homo sapiens_hsa030200.48278114
46Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.47952395
47Herpes simplex infection_Homo sapiens_hsa051680.46412696
48Central carbon metabolism in cancer_Homo sapiens_hsa052300.45997620
49Colorectal cancer_Homo sapiens_hsa052100.45518887
50Apoptosis_Homo sapiens_hsa042100.41776919
51TGF-beta signaling pathway_Homo sapiens_hsa043500.41031181
52Hepatitis B_Homo sapiens_hsa051610.40590610
53Glioma_Homo sapiens_hsa052140.39956613
54Renin-angiotensin system_Homo sapiens_hsa046140.38820474
55Pancreatic cancer_Homo sapiens_hsa052120.38763251
56Basal cell carcinoma_Homo sapiens_hsa052170.38495931
57Biosynthesis of amino acids_Homo sapiens_hsa012300.37751185
58Hippo signaling pathway_Homo sapiens_hsa043900.37003318
59Proteoglycans in cancer_Homo sapiens_hsa052050.36855382
60Prostate cancer_Homo sapiens_hsa052150.34039532
61Antigen processing and presentation_Homo sapiens_hsa046120.33296535
62Vitamin B6 metabolism_Homo sapiens_hsa007500.32950872
63Adherens junction_Homo sapiens_hsa045200.31567774
64Melanoma_Homo sapiens_hsa052180.30954015
65FoxO signaling pathway_Homo sapiens_hsa040680.28957109
66Basal transcription factors_Homo sapiens_hsa030220.27281689
67Viral myocarditis_Homo sapiens_hsa054160.26343134
68Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.25882312
69Pathways in cancer_Homo sapiens_hsa052000.25710455
70Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.25569819
71Leishmaniasis_Homo sapiens_hsa051400.25032667
72Notch signaling pathway_Homo sapiens_hsa043300.25018232
73B cell receptor signaling pathway_Homo sapiens_hsa046620.24924938
74Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.24826045
75Thyroid cancer_Homo sapiens_hsa052160.24602183
76Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.24194569
77Endometrial cancer_Homo sapiens_hsa052130.23446357
78Thyroid hormone signaling pathway_Homo sapiens_hsa049190.22868650
79Focal adhesion_Homo sapiens_hsa045100.22030621
80Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.21978991
81Cyanoamino acid metabolism_Homo sapiens_hsa004600.21880268
82Purine metabolism_Homo sapiens_hsa002300.21565095
83NF-kappa B signaling pathway_Homo sapiens_hsa040640.21553663
84Tight junction_Homo sapiens_hsa045300.21542667
85HIF-1 signaling pathway_Homo sapiens_hsa040660.21115587
86Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.20040652
87Leukocyte transendothelial migration_Homo sapiens_hsa046700.17317668
88T cell receptor signaling pathway_Homo sapiens_hsa046600.16002267
89Measles_Homo sapiens_hsa051620.15972591
90Hematopoietic cell lineage_Homo sapiens_hsa046400.15287275
91Hedgehog signaling pathway_Homo sapiens_hsa043400.14873224
92Legionellosis_Homo sapiens_hsa051340.13533415
93AMPK signaling pathway_Homo sapiens_hsa041520.13263514
94Phosphatidylinositol signaling system_Homo sapiens_hsa040700.13154858
95ECM-receptor interaction_Homo sapiens_hsa045120.12266276
96Pentose phosphate pathway_Homo sapiens_hsa000300.12258622
97Platelet activation_Homo sapiens_hsa046110.12113006
98PI3K-Akt signaling pathway_Homo sapiens_hsa041510.11727547
99Regulation of actin cytoskeleton_Homo sapiens_hsa048100.10200325
100Inositol phosphate metabolism_Homo sapiens_hsa005620.09966730
101Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.09880339
102Carbon metabolism_Homo sapiens_hsa012000.09756971
103Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.09730170
104Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.09127697
105Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.08696995
106Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.08096800
107Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.07916248
108Cysteine and methionine metabolism_Homo sapiens_hsa002700.07786447
109ErbB signaling pathway_Homo sapiens_hsa040120.07762463
110Influenza A_Homo sapiens_hsa051640.07161091
111AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.06699304
112Fatty acid biosynthesis_Homo sapiens_hsa000610.06537491
113Drug metabolism - other enzymes_Homo sapiens_hsa009830.06425842
114Wnt signaling pathway_Homo sapiens_hsa043100.06238223
115RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.05696701
116Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.05579677
117Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.05555604
118Acute myeloid leukemia_Homo sapiens_hsa052210.05458710
119Sulfur relay system_Homo sapiens_hsa041220.05163301
120Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.04714205
121Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.04687833
122Toxoplasmosis_Homo sapiens_hsa051450.03421685
123Proteasome_Homo sapiens_hsa030500.01033105

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