HIST2H2AB

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene contain a palindromic termination element. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mucosal immune response (GO:0002385)9.43941000
2organ or tissue specific immune response (GO:0002251)8.61759115
3protein localization to kinetochore (GO:0034501)7.03169851
4DNA replication-dependent nucleosome assembly (GO:0006335)6.87421880
5DNA replication-dependent nucleosome organization (GO:0034723)6.87421880
6protein localization to chromosome, centromeric region (GO:0071459)6.29787357
7regulation of histone H3-K9 methylation (GO:0051570)5.91677076
8DNA unwinding involved in DNA replication (GO:0006268)5.73931477
9sister chromatid segregation (GO:0000819)5.71041619
10nuclear pore complex assembly (GO:0051292)5.67220788
11meiotic chromosome segregation (GO:0045132)5.48661772
12nucleosome assembly (GO:0006334)5.46647801
13regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450915.45464115
14mitotic sister chromatid segregation (GO:0000070)5.26120930
15nuclear pore organization (GO:0006999)5.23259805
16mitotic chromosome condensation (GO:0007076)5.22456406
17chromatin assembly (GO:0031497)5.04083266
18negative regulation of hematopoietic progenitor cell differentiation (GO:1901533)5.02982710
19attachment of spindle microtubules to kinetochore (GO:0008608)4.94338309
20chromatin remodeling at centromere (GO:0031055)4.92365427
21CENP-A containing nucleosome assembly (GO:0034080)4.89285598
22chromatin assembly or disassembly (GO:0006333)4.85425126
23kinetochore organization (GO:0051383)4.76938044
24protein-DNA complex assembly (GO:0065004)4.68687550
25nucleosome organization (GO:0034728)4.68484086
26pore complex assembly (GO:0046931)4.43471035
27regulation of spindle organization (GO:0090224)4.38761573
28mitotic metaphase plate congression (GO:0007080)4.37151041
29metaphase plate congression (GO:0051310)4.27692370
30DNA topological change (GO:0006265)4.16334730
31DNA replication-independent nucleosome organization (GO:0034724)4.15043913
32DNA replication-independent nucleosome assembly (GO:0006336)4.15043913
33protein-DNA complex subunit organization (GO:0071824)4.15034123
34folic acid-containing compound biosynthetic process (GO:0009396)4.06785799
35protein K6-linked ubiquitination (GO:0085020)4.06408526
36histone exchange (GO:0043486)4.02041311
37mitotic recombination (GO:0006312)4.01670536
38mitotic nuclear envelope disassembly (GO:0007077)3.99898119
39establishment of chromosome localization (GO:0051303)3.99874844
40DNA duplex unwinding (GO:0032508)3.93312477
41DNA geometric change (GO:0032392)3.92820281
42protein localization to chromosome (GO:0034502)3.91905935
43defense response to Gram-positive bacterium (GO:0050830)3.89258125
44mitotic sister chromatid cohesion (GO:0007064)3.86758262
45chromosome condensation (GO:0030261)3.82467362
46regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.80554537
47viral mRNA export from host cell nucleus (GO:0046784)3.79778421
48nuclear envelope disassembly (GO:0051081)3.78622418
49membrane disassembly (GO:0030397)3.78622418
50DNA strand elongation involved in DNA replication (GO:0006271)3.75953037
51dosage compensation (GO:0007549)3.75568654
52telomere maintenance via semi-conservative replication (GO:0032201)3.72675192
53regulation of mammary gland epithelial cell proliferation (GO:0033599)3.72218202
54chromosome segregation (GO:0007059)3.69571732
55regulation of mitotic spindle organization (GO:0060236)3.68403266
56antibacterial humoral response (GO:0019731)3.66306069
57DNA replication initiation (GO:0006270)3.65894689
58somatic hypermutation of immunoglobulin genes (GO:0016446)3.65192082
59somatic diversification of immune receptors via somatic mutation (GO:0002566)3.65192082
60regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.65133721
61innate immune response in mucosa (GO:0002227)3.64762408
62regulation of megakaryocyte differentiation (GO:0045652)3.63842616
63negative regulation of DNA repair (GO:0045738)3.63711333
64DNA strand elongation (GO:0022616)3.61347694
65peptidyl-lysine dimethylation (GO:0018027)3.57610547
66spindle checkpoint (GO:0031577)3.57208580
67kinetochore assembly (GO:0051382)3.50136340
68telomere maintenance via recombination (GO:0000722)3.48597428
69regulation of translational fidelity (GO:0006450)3.48119130
70positive regulation of mitotic sister chromatid separation (GO:1901970)3.47986139
71positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.47986139
72positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.47986139
73regulation of chromosome segregation (GO:0051983)3.44509689
74DNA conformation change (GO:0071103)3.42807718
75ribosomal small subunit assembly (GO:0000028)3.42267907
76DNA packaging (GO:0006323)3.39173553
77translesion synthesis (GO:0019985)3.38142757
78antimicrobial humoral response (GO:0019730)3.36941630
79regulation of centrosome cycle (GO:0046605)3.36779525
80negative regulation of histone methylation (GO:0031061)3.33322829
81resolution of meiotic recombination intermediates (GO:0000712)3.33055204
82IMP biosynthetic process (GO:0006188)3.30768797
83mature B cell differentiation involved in immune response (GO:0002313)3.29875148
84spindle assembly checkpoint (GO:0071173)3.28947566
85regulation of centriole replication (GO:0046599)3.28534416
86regulation of mitotic metaphase/anaphase transition (GO:0030071)3.26804965
87establishment of mitotic spindle localization (GO:0040001)3.26130812
88regulation of DNA endoreduplication (GO:0032875)3.22241574
89regulation of gene silencing (GO:0060968)3.19665724
90histone lysine demethylation (GO:0070076)3.17778918
91regulation of sister chromatid segregation (GO:0033045)3.17744436
92regulation of mitotic sister chromatid separation (GO:0010965)3.17744436
93regulation of mitotic sister chromatid segregation (GO:0033047)3.17744436
94regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.17690977
95negative regulation of chromosome segregation (GO:0051985)3.17561128
96DNA replication checkpoint (GO:0000076)3.16898699
97negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.16563586
98negative regulation of sister chromatid segregation (GO:0033046)3.16563586
99negative regulation of mitotic sister chromatid separation (GO:2000816)3.16563586
100negative regulation of mitotic sister chromatid segregation (GO:0033048)3.16563586
101ATP-dependent chromatin remodeling (GO:0043044)3.16476635
102telomere maintenance (GO:0000723)3.16159635
103IMP metabolic process (GO:0046040)3.15256947
104positive regulation of chromosome segregation (GO:0051984)3.14860909
105mitochondrial DNA metabolic process (GO:0032042)3.13767431
106spindle assembly involved in mitosis (GO:0090307)3.13728542
107nucleotide-excision repair, DNA gap filling (GO:0006297)3.13298120
108telomere organization (GO:0032200)3.13052648
109regulation of centrosome duplication (GO:0010824)3.11658041
110regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.11258988
111regulation of mitotic spindle checkpoint (GO:1903504)3.11258988
112histone demethylation (GO:0016577)3.10208013
113regulation of sister chromatid cohesion (GO:0007063)3.06041521
114DNA synthesis involved in DNA repair (GO:0000731)3.05893894
115negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.05070231
116V(D)J recombination (GO:0033151)3.01819623
117negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)2.92214014
118histone phosphorylation (GO:0016572)2.86397260
119double-strand break repair via nonhomologous end joining (GO:0006303)2.82066880
120non-recombinational repair (GO:0000726)2.82066880
121protein complex localization (GO:0031503)2.81810613
122mature B cell differentiation (GO:0002335)2.81472795
123mitotic spindle assembly checkpoint (GO:0007094)2.79537637
124cellular protein complex localization (GO:0034629)2.77828873
125B cell receptor signaling pathway (GO:0050853)2.76962992
126positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.75918003
127protein demethylation (GO:0006482)2.75813884
128protein dealkylation (GO:0008214)2.75813884
129telomere maintenance via telomere lengthening (GO:0010833)2.71973598
130embryonic process involved in female pregnancy (GO:0060136)2.71383104
131maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.71012736

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.42625218
2FOXM1_23109430_ChIP-Seq_U2OS_Human5.99356199
3E2F4_17652178_ChIP-ChIP_JURKAT_Human4.69359985
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.55689174
5HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.23019419
6* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.13297541
7MYC_18555785_ChIP-Seq_MESCs_Mouse2.55389308
8EGR1_19374776_ChIP-ChIP_THP-1_Human2.46157322
9SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.38600610
10* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.27893442
11E2F1_21310950_ChIP-Seq_MCF-7_Human2.20758388
12NELFA_20434984_ChIP-Seq_ESCs_Mouse2.08460422
13FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse13.0531332
14* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.95603803
15AR_21909140_ChIP-Seq_LNCAP_Human1.92509223
16* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.91839766
17EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.84120458
18MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.79316372
19EGR1_23403033_ChIP-Seq_LIVER_Mouse1.70857844
20CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.65699722
21HOXB4_20404135_ChIP-ChIP_EML_Mouse1.63047347
22RBPJ_22232070_ChIP-Seq_NCS_Mouse1.62876899
23KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.61893308
24* SOX2_16153702_ChIP-ChIP_HESCs_Human1.61283932
25IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.58399495
26TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.57837181
27ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.57787805
28MYC_19079543_ChIP-ChIP_MESCs_Mouse1.57769312
29* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.56935091
30SALL1_21062744_ChIP-ChIP_HESCs_Human1.56820295
31* VDR_23849224_ChIP-Seq_CD4+_Human1.56712417
32CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.54224044
33ERG_20887958_ChIP-Seq_HPC-7_Mouse1.53671043
34ELK1_19687146_ChIP-ChIP_HELA_Human1.52918170
35SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.52297950
36IRF1_19129219_ChIP-ChIP_H3396_Human1.37714529
37ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.37410824
38MYC_18358816_ChIP-ChIP_MESCs_Mouse1.35951283
39SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.29217518
40FOXP3_21729870_ChIP-Seq_TREG_Human1.28719282
41XRN2_22483619_ChIP-Seq_HELA_Human1.26282673
42HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.25634825
43KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.21990627
44POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.21279182
45MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.20305127
46SOX2_18555785_ChIP-Seq_MESCs_Mouse1.19795898
47KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.18247253
48STAT4_19710469_ChIP-ChIP_TH1__Mouse1.15509065
49HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.13630103
50* POU5F1_16153702_ChIP-ChIP_HESCs_Human1.11025597
51E2F1_18555785_ChIP-Seq_MESCs_Mouse1.10506078
52BRD4_27068464_Chip-Seq_AML-cells_Mouse1.06252050
53MYC_22102868_ChIP-Seq_BL_Human1.06086670
54MYCN_18555785_ChIP-Seq_MESCs_Mouse1.06067311
55POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.05963351
56EST1_17652178_ChIP-ChIP_JURKAT_Human1.05354991
57TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.05322496
58PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.05012869
59HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.04150636
60* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.03575518
61RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.01900927
62NANOG_16153702_ChIP-ChIP_HESCs_Human1.01857866
63CREB1_15753290_ChIP-ChIP_HEK293T_Human1.01086018
64POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.01083358
65ESR1_15608294_ChIP-ChIP_MCF-7_Human0.97091133
66FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.96905002
67YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.96880026
68ZFX_18555785_ChIP-Seq_MESCs_Mouse0.96258045
69DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.96038550
70GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.94228645
71SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.93965478
72TTF2_22483619_ChIP-Seq_HELA_Human0.93924649
73KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.92408397
74MAF_26560356_Chip-Seq_TH1_Human0.90826558
75MYC_18940864_ChIP-ChIP_HL60_Human0.90607694
76STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.89910619
77GATA1_22025678_ChIP-Seq_K562_Human0.89610850
78* VDR_21846776_ChIP-Seq_THP-1_Human0.89377037
79NANOG_18555785_ChIP-Seq_MESCs_Mouse0.89278787
80ETS1_20019798_ChIP-Seq_JURKAT_Human0.88310116
81* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.88216695
82NOTCH1_21737748_ChIP-Seq_TLL_Human0.86763330
83DCP1A_22483619_ChIP-Seq_HELA_Human0.86309636
84STAT3_1855785_ChIP-Seq_MESCs_Mouse0.84871897
85NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.84828365
86GABP_17652178_ChIP-ChIP_JURKAT_Human0.84437080
87CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.83631848
88IRF8_22096565_ChIP-ChIP_GC-B_Human0.83592132
89CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.82581370
90VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.82155757
91FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.82127320
92* SOX2_18692474_ChIP-Seq_MESCs_Mouse0.80896252
93DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.80061659
94SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.77846214
95CIITA_25753668_ChIP-Seq_RAJI_Human0.77432370
96TP63_17297297_ChIP-ChIP_HaCaT_Human0.76833195
97* PKCTHETA_26484144_Chip-Seq_BREAST_Human0.76824198
98MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.76217667
99THAP11_20581084_ChIP-Seq_MESCs_Mouse0.76167856
100ETS1_22383799_ChIP-Seq_G1ME_Mouse0.75784029
101GATA2_22383799_ChIP-Seq_G1ME_Mouse0.74105828
102TCF3_18692474_ChIP-Seq_MESCs_Mouse0.74003996
103RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.73149927
104ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.71878252
105PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.70993370
106* KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.70065039
107E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.68787758
108KDM5A_27292631_Chip-Seq_BREAST_Human0.67350550
109TFEB_21752829_ChIP-Seq_HELA_Human0.67191634
110CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.66056273
111JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.64596371
112ZNF263_19887448_ChIP-Seq_K562_Human0.64426633
113RUNX1_22412390_ChIP-Seq_EML_Mouse0.64244940
114* MYB_26560356_Chip-Seq_TH1_Human0.63510778
115CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.63160391
116ELF1_17652178_ChIP-ChIP_JURKAT_Human0.61437119
117SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.60346613
118* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.58013786

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability4.95189163
2MP0003693_abnormal_embryo_hatching4.93404448
3MP0003111_abnormal_nucleus_morphology4.31153705
4MP0003077_abnormal_cell_cycle3.74852740
5MP0010307_abnormal_tumor_latency3.53890364
6MP0004957_abnormal_blastocyst_morpholog3.17559073
7MP0008057_abnormal_DNA_replication3.06143075
8MP0008058_abnormal_DNA_repair2.82175004
9MP0008007_abnormal_cellular_replicative2.60614408
10MP0002396_abnormal_hematopoietic_system2.46796755
11MP0004185_abnormal_adipocyte_glucose2.28319984
12MP0000350_abnormal_cell_proliferation2.23051057
13MP0006054_spinal_hemorrhage2.22493447
14MP0010352_gastrointestinal_tract_polyps2.17352060
15MP0004808_abnormal_hematopoietic_stem2.15437279
16MP0003123_paternal_imprinting2.12047235
17MP0008932_abnormal_embryonic_tissue2.02512558
18MP0001661_extended_life_span1.92573934
19MP0001293_anophthalmia1.89055811
20MP0005076_abnormal_cell_differentiation1.88603077
21MP0001730_embryonic_growth_arrest1.88013289
22MP0000569_abnormal_digit_pigmentation1.81542102
23MP0003705_abnormal_hypodermis_morpholog1.80193635
24MP0000490_abnormal_crypts_of1.67469098
25MP0010234_abnormal_vibrissa_follicle1.66435384
26MP0002095_abnormal_skin_pigmentation1.61836836
27MP0008877_abnormal_DNA_methylation1.57019034
28MP0000372_irregular_coat_pigmentation1.56150678
29MP0001697_abnormal_embryo_size1.55013536
30MP0002086_abnormal_extraembryonic_tissu1.48958173
31MP0005645_abnormal_hypothalamus_physiol1.48637574
32MP0004197_abnormal_fetal_growth/weight/1.47858764
33MP0002019_abnormal_tumor_incidence1.45713565
34MP0005380_embryogenesis_phenotype1.43206643
35MP0001672_abnormal_embryogenesis/_devel1.43206643
36MP0000371_diluted_coat_color1.42285701
37MP0003121_genomic_imprinting1.41938499
38MP0000313_abnormal_cell_death1.41572105
39MP0000015_abnormal_ear_pigmentation1.39859580
40MP0002080_prenatal_lethality1.36904410
41MP0002085_abnormal_embryonic_tissue1.35302033
42MP0005171_absent_coat_pigmentation1.34490851
43MP0002084_abnormal_developmental_patter1.32286820
44MP0000358_abnormal_cell_content/1.31542553
45MP0002398_abnormal_bone_marrow1.29547650
46MP0002166_altered_tumor_susceptibility1.27118676
47MP0006035_abnormal_mitochondrial_morpho1.26830350
48MP0002006_tumorigenesis1.24867151
49MP0000703_abnormal_thymus_morphology1.24085287
50MP0005408_hypopigmentation1.22788725
51MP0003937_abnormal_limbs/digits/tail_de1.22781592
52MP0003984_embryonic_growth_retardation1.19739390
53MP0005083_abnormal_biliary_tract1.19203179
54MP0003786_premature_aging1.17858876
55MP0002722_abnormal_immune_system1.17700552
56MP0002088_abnormal_embryonic_growth/wei1.17560319
57MP0009697_abnormal_copulation1.15931192
58MP0002160_abnormal_reproductive_system1.14688685
59MP0003566_abnormal_cell_adhesion1.14096048
60MP0005220_abnormal_exocrine_pancreas1.13726215
61MP0005410_abnormal_fertilization1.13686225
62MP0002092_abnormal_eye_morphology1.12925226
63MP0000689_abnormal_spleen_morphology1.12115416
64MP0002163_abnormal_gland_morphology1.10807188
65MP0009703_decreased_birth_body1.09927508
66MP0003890_abnormal_embryonic-extraembry1.06279365
67MP0002075_abnormal_coat/hair_pigmentati1.06134892
68MP0009672_abnormal_birth_weight1.04835750
69MP0001915_intracranial_hemorrhage1.04248452
70MP0003300_gastrointestinal_ulcer1.01017199
71MP0001346_abnormal_lacrimal_gland1.00542371
72MP0001835_abnormal_antigen_presentation0.99300670
73MP0005451_abnormal_body_composition0.95035751
74MP0001929_abnormal_gametogenesis0.94771574
75MP0001800_abnormal_humoral_immune0.94030915
76MP0003303_peritoneal_inflammation0.93527442
77MP0004381_abnormal_hair_follicle0.93391129
78MP0000733_abnormal_muscle_development0.93265604
79MP0002429_abnormal_blood_cell0.92946432
80MP0002452_abnormal_antigen_presenting0.92882369
81MP0005174_abnormal_tail_pigmentation0.91545651
82MP0001873_stomach_inflammation0.86942290
83MP0005621_abnormal_cell_physiology0.86576968
84MP0002009_preneoplasia0.86477901
85MP0000716_abnormal_immune_system0.85850979
86MP0001727_abnormal_embryo_implantation0.85715325
87MP0002111_abnormal_tail_morphology0.84978827
88MP0002210_abnormal_sex_determination0.84186152
89MP0000465_gastrointestinal_hemorrhage0.83925729
90MP0002420_abnormal_adaptive_immunity0.82618047
91MP0003221_abnormal_cardiomyocyte_apopto0.82235391
92MP0005623_abnormal_meninges_morphology0.81601112
93MP0005384_cellular_phenotype0.81235985
94MP0001819_abnormal_immune_cell0.80740339
95MP0005671_abnormal_response_to0.80118907
96MP0002697_abnormal_eye_size0.79047701
97MP0000685_abnormal_immune_system0.78954636
98MP0001849_ear_inflammation0.78066974
99MP0001545_abnormal_hematopoietic_system0.77500318
100MP0005397_hematopoietic_system_phenotyp0.77500318
101MP0000537_abnormal_urethra_morphology0.77357886
102MP0003453_abnormal_keratinocyte_physiol0.75972999
103MP0003941_abnormal_skin_development0.74819363
104MP0001186_pigmentation_phenotype0.74674375
105MP0005464_abnormal_platelet_physiology0.74289752
106MP0002928_abnormal_bile_duct0.72922076
107MP0008438_abnormal_cutaneous_collagen0.72208605
108MP0002877_abnormal_melanocyte_morpholog0.71997902
109MP0001145_abnormal_male_reproductive0.71541660
110MP0003763_abnormal_thymus_physiology0.71491363
111MP0009278_abnormal_bone_marrow0.70780891
112MP0010678_abnormal_skin_adnexa0.70254957
113MP0009053_abnormal_anal_canal0.70145671
114MP0003567_abnormal_fetal_cardiomyocyte0.69803104
115MP0000432_abnormal_head_morphology0.69676308
116MP0003448_altered_tumor_morphology0.67534863
117MP0000653_abnormal_sex_gland0.67431571
118MP0005501_abnormal_skin_physiology0.67341493
119MP0005000_abnormal_immune_tolerance0.67127497
120MP0002060_abnormal_skin_morphology0.66690317
121MP0000428_abnormal_craniofacial_morphol0.65805667
122MP0005310_abnormal_salivary_gland0.65767306
123MP0004947_skin_inflammation0.65256125
124MP0002723_abnormal_immune_serum0.64373396
125MP0000427_abnormal_hair_cycle0.64165225
126MP0001191_abnormal_skin_condition0.63488385
127MP0009931_abnormal_skin_appearance0.63312143
128MP0001216_abnormal_epidermal_layer0.63034794
129MP0008770_decreased_survivor_rate0.62695816
130MP0004233_abnormal_muscle_weight0.62298116
131MP0000013_abnormal_adipose_tissue0.62194851
132MP0000003_abnormal_adipose_tissue0.62166060
133MP0005666_abnormal_adipose_tissue0.61622264
134MP0003186_abnormal_redox_activity0.60023874
135MP0005389_reproductive_system_phenotype0.59150577

Predicted human phenotypes

RankGene SetZ-score
1IgM deficiency (HP:0002850)5.39537019
2IgA deficiency (HP:0002720)5.17658457
3Colitis (HP:0002583)4.64731732
4Agnosia (HP:0010524)3.92601964
5Chromsome breakage (HP:0040012)3.91061966
6Cutaneous melanoma (HP:0012056)3.86247088
7Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.82133290
8Short 4th metacarpal (HP:0010044)3.82133290
9Reticulocytopenia (HP:0001896)3.59445416
10Impulsivity (HP:0100710)3.55095659
11Chromosomal breakage induced by crosslinking agents (HP:0003221)3.50996614
12Abnormality of chromosome stability (HP:0003220)3.50265321
13Thrombocytosis (HP:0001894)3.17798958
14Basal cell carcinoma (HP:0002671)3.13499218
15Colon cancer (HP:0003003)3.10216943
16B lymphocytopenia (HP:0010976)3.07030083
17Absent frontal sinuses (HP:0002688)2.98711914
18Medulloblastoma (HP:0002885)2.97381573
19Birth length less than 3rd percentile (HP:0003561)2.83396488
20Gastrointestinal stroma tumor (HP:0100723)2.79037911
21Microvesicular hepatic steatosis (HP:0001414)2.78807223
22Volvulus (HP:0002580)2.76705349
23Abnormal platelet volume (HP:0011876)2.75727296
24Increased mean platelet volume (HP:0011877)2.74249910
25Abnormality of the anterior horn cell (HP:0006802)2.73137273
26Degeneration of anterior horn cells (HP:0002398)2.73137273
27Rhabdomyosarcoma (HP:0002859)2.71158427
28Ependymoma (HP:0002888)2.70832600
29Amaurosis fugax (HP:0100576)2.69977379
30Selective tooth agenesis (HP:0001592)2.57408026
31Meckel diverticulum (HP:0002245)2.57379780
32Acute lymphatic leukemia (HP:0006721)2.57351995
33Myelodysplasia (HP:0002863)2.52743827
34Aplasia/Hypoplasia of the sacrum (HP:0008517)2.50635383
35Degeneration of the lateral corticospinal tracts (HP:0002314)2.46451727
36Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.46451727
37Small intestinal stenosis (HP:0012848)2.46371150
38Duodenal stenosis (HP:0100867)2.46371150
39Abnormality of B cell number (HP:0010975)2.45667550
40Progressive external ophthalmoplegia (HP:0000590)2.45238254
41Inflammation of the large intestine (HP:0002037)2.44325585
42Squamous cell carcinoma (HP:0002860)2.43137794
43Abnormality of the ileum (HP:0001549)2.42984189
44Poikiloderma (HP:0001029)2.41419871
45Acanthocytosis (HP:0001927)2.40514376
46Hypopigmentation of the fundus (HP:0007894)2.40414234
47Neoplasm of the oral cavity (HP:0100649)2.40411192
48Sandal gap (HP:0001852)2.38508934
49Abnormality of the 4th metacarpal (HP:0010012)2.38339538
50Abnormality of the distal phalanx of the thumb (HP:0009617)2.37103117
51Biliary tract neoplasm (HP:0100574)2.36982388
52Short thumb (HP:0009778)2.35996070
53Sloping forehead (HP:0000340)2.35942190
54Recurrent sinusitis (HP:0011108)2.35426968
55Progressive muscle weakness (HP:0003323)2.34861586
56Aplasia/Hypoplasia of the uvula (HP:0010293)2.33953269
57High pitched voice (HP:0001620)2.32812676
5811 pairs of ribs (HP:0000878)2.31563975
59Abnormality of the preputium (HP:0100587)2.31484495
60Gastrointestinal inflammation (HP:0004386)2.27782147
61Papilledema (HP:0001085)2.27331733
62Abnormality of pyrimidine metabolism (HP:0004353)2.26061692
63Nephroblastoma (Wilms tumor) (HP:0002667)2.25459935
64Increased nuchal translucency (HP:0010880)2.24666845
65Freckling (HP:0001480)2.24486292
66Cortical dysplasia (HP:0002539)2.23334324
67Astrocytoma (HP:0009592)2.21282272
68Abnormality of the astrocytes (HP:0100707)2.21282272
69Abnormal lung lobation (HP:0002101)2.20110783
70Cafe-au-lait spot (HP:0000957)2.20082963
71Asymmetry of the thorax (HP:0001555)2.19282723
72Prominent nose (HP:0000448)2.18685665
73Agammaglobulinemia (HP:0004432)2.17876371
74Entropion (HP:0000621)2.16669386
75Lymphopenia (HP:0001888)2.14012439
76Abnormality of cells of the lymphoid lineage (HP:0012140)2.13345216
77Absent thumb (HP:0009777)2.13272762
78Subacute progressive viral hepatitis (HP:0006572)2.13215352
79Ectopic kidney (HP:0000086)2.11935446
80Embryonal renal neoplasm (HP:0011794)2.11650300
81Down-sloping shoulders (HP:0200021)2.11610055
82Recurrent viral infections (HP:0004429)2.11009798
83Autoimmune hemolytic anemia (HP:0001890)2.10601796
84Prostate neoplasm (HP:0100787)2.10271917
85Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)2.09893342
86Aplasia/Hypoplasia of the patella (HP:0006498)2.09610780
87Cellulitis (HP:0100658)2.09421013
88Lymphoma (HP:0002665)2.09314891
89Interstitial pulmonary disease (HP:0006530)2.08986550
90Abnormality of the labia minora (HP:0012880)2.08262092
91Abnormality of the parietal bone (HP:0002696)2.07995712
92Neoplasm of the heart (HP:0100544)2.06740372
93Leukopenia (HP:0001882)2.06585235
94Arteriovenous malformation (HP:0100026)2.05821742
95Viral hepatitis (HP:0006562)2.05591327
96Hypochromic microcytic anemia (HP:0004840)2.04746349
97Broad face (HP:0000283)2.03672156
98Hematochezia (HP:0002573)2.02394777
99Recurrent bronchitis (HP:0002837)2.02221334
100Abnormality of cells of the erythroid lineage (HP:0012130)2.01988492
101Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.01777778
102Glioma (HP:0009733)2.01110801
103Short humerus (HP:0005792)2.01099580
104Ureteral duplication (HP:0000073)1.98431231
105Spastic diplegia (HP:0001264)1.98411232
106Abnormality of the duodenum (HP:0002246)1.98175115
107Abnormality of the renal collecting system (HP:0004742)1.97895390
108Neoplasm of striated muscle (HP:0009728)1.96582319
109Duplicated collecting system (HP:0000081)1.96519960
110Deformed sella turcica (HP:0002681)1.95222788
111Pallor (HP:0000980)1.93300504
112Rectal prolapse (HP:0002035)1.92817725
113Abnormality of the fingertips (HP:0001211)1.92121222
114Aplasia/hypoplasia of the humerus (HP:0006507)1.90540218
115Facial hemangioma (HP:0000329)1.90203230
116Hyperacusis (HP:0010780)1.89734188
117Pseudobulbar signs (HP:0002200)1.89153025
118Bone marrow hypocellularity (HP:0005528)1.89077555
119Hypergonadotropic hypogonadism (HP:0000815)1.88074709
120Hepatitis (HP:0012115)1.87833531
121Clubbing of toes (HP:0100760)1.87485179
122Erythema (HP:0010783)1.86099500
123Thyroiditis (HP:0100646)1.85561038
124Abnormality of the intervertebral disk (HP:0005108)1.83605070
125Intestinal fistula (HP:0100819)1.83515082
126Oral leukoplakia (HP:0002745)1.82870468
127Premature graying of hair (HP:0002216)1.82766193
128Spinal cord lesions (HP:0100561)1.82527633
129Syringomyelia (HP:0003396)1.82527633
130Abnormality of the carotid arteries (HP:0005344)1.81857743
131Deep philtrum (HP:0002002)1.80971967
132Abnormality of DNA repair (HP:0003254)1.80502017
133Large earlobe (HP:0009748)1.79553541
134Long eyelashes (HP:0000527)1.78884411
135Poikilocytosis (HP:0004447)1.78056360
136Abnormality of the pulmonary veins (HP:0011718)1.77966110
137Deviation of the thumb (HP:0009603)1.77255175
138Osteolytic defects of the phalanges of the hand (HP:0009771)1.77233105
139Osteolytic defects of the hand bones (HP:0009699)1.77233105
140Rectovaginal fistula (HP:0000143)1.76427483
141Rectal fistula (HP:0100590)1.76427483
142Abnormal number of erythroid precursors (HP:0012131)1.76147115
143Malignant gastrointestinal tract tumors (HP:0006749)1.74776736
144Gastrointestinal carcinoma (HP:0002672)1.74776736
145Chronic diarrhea (HP:0002028)1.74491085
146Missing ribs (HP:0000921)1.74061523
147Truncal obesity (HP:0001956)1.73175449
148Cutis marmorata (HP:0000965)1.73063473
149Broad distal phalanx of finger (HP:0009836)1.71838488
150Micronodular cirrhosis (HP:0001413)1.70543273
151Abnormality of the frontal sinuses (HP:0002687)1.70158387
152Dyschromatopsia (HP:0007641)1.70151418
153Neoplasm of the pancreas (HP:0002894)1.69341379
154Abnormality of nail color (HP:0100643)1.68964832
155Neoplasm of the colon (HP:0100273)1.68562277
156Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.68342200
157Embryonal neoplasm (HP:0002898)1.68154083

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TLK17.62883184
2ZAK5.52310385
3NEK23.49588633
4STK43.48049557
5VRK13.21035517
6CDC73.07033081
7SCYL22.59056940
8WEE12.45207817
9CDK122.21491493
10RPS6KA52.21341960
11BUB12.20773842
12SRPK12.11685408
13AURKB1.90858007
14NEK11.85743657
15CHEK21.79888454
16MAP3K101.78296483
17TRIB31.66869354
18MAP3K81.63993099
19BRSK21.62108615
20TTK1.50003614
21PLK11.48650919
22PIM11.46046603
23DYRK31.39910666
24STK101.35680597
25MKNK11.31553730
26SMG11.29626582
27AURKA1.26010989
28PKN21.24868800
29FLT31.21005756
30ATR1.19417329
31EIF2AK21.18217965
32PLK31.16276290
33CDK91.16093986
34EEF2K1.15301255
35ACVR1B1.13228103
36TTN1.11543065
37RPS6KB21.06944664
38CDK61.03920264
39CCNB10.97729137
40RPS6KA40.97072497
41CDK40.94327690
42CHEK10.94264209
43FRK0.92507874
44PASK0.92189441
45MKNK20.84373853
46EIF2AK30.79532276
47TEC0.79229197
48ATM0.78785429
49CDK80.75740668
50STK30.74160798
51MARK30.73169609
52DAPK30.71344847
53CDK70.70457568
54ICK0.69593227
55CAMK1D0.69254161
56EPHA20.68634097
57BRD40.67097960
58TAF10.66589347
59EIF2AK10.66201627
60MAP2K30.66153147
61CDK20.65850986
62BRAF0.61252700
63PKN10.60239817
64GRK60.58536780
65IRAK40.57118255
66PRPF4B0.56330615
67PBK0.55824548
68MAPK110.55817876
69LRRK20.54634314
70BRSK10.54180296
71ERBB30.54072700
72CDK10.53944662
73IRAK30.51712963
74STK160.48378422
75TESK20.47404474
76MAP4K10.47103439
77CAMK40.44846490
78EPHA30.43199907
79BLK0.41719574
80DYRK1B0.41534890
81MELK0.41047990
82MAP2K70.40243183
83PLK40.36365152
84PRKDC0.35572910
85TGFBR10.35307101
86SYK0.33780853
87ALK0.33554670
88RPS6KB10.32297432
89TRPM70.32266046
90TSSK60.31777216
91CSF1R0.31232470
92JAK30.30884337
93MAP2K40.30548046
94PIM20.30479706
95MST1R0.30178964
96CSNK2A20.30116819
97RAF10.29786722
98IRAK20.29320794
99PIK3CG0.29061782
100MAPK140.28958089
101TESK10.27355827
102PAK10.26697567
103LATS10.26662428
104BTK0.26330397
105NEK60.26002577
106CSNK1D0.25872739
107CAMKK20.24050922
108ZAP700.23974621
109MAP3K40.23452855
110LYN0.21612929
111AKT20.21543309
112CSNK1A1L0.21322449
113MAP3K60.20527302
114MAP3K20.20452632
115RET0.20311226
116MET0.19798369
117PAK40.19537156
118AKT10.19431092
119PRKAA10.18978358
120NME20.18930042
121JAK20.18906223
122BCKDK0.18819038
123KDR0.18606654
124CSNK1G10.18441624
125CSNK1G30.17829554
126MTOR0.17693974
127PRKCQ0.17484573
128NEK90.16417611
129RIPK10.16357473
130CSNK2A10.16338756
131RPS6KC10.15207214
132RPS6KL10.15207214
133IKBKB0.14753216
134MAP3K90.13571843
135MAP3K140.12998147
136ILK0.09841172
137RPS6KA10.09544273

Predicted pathways (KEGG)

RankGene SetZ-score
1* Systemic lupus erythematosus_Homo sapiens_hsa053229.73262477
2* Alcoholism_Homo sapiens_hsa050345.39986334
3DNA replication_Homo sapiens_hsa030303.38224557
4Viral carcinogenesis_Homo sapiens_hsa052033.09005732
5Mismatch repair_Homo sapiens_hsa034303.07547297
6Non-homologous end-joining_Homo sapiens_hsa034502.41381327
7Cell cycle_Homo sapiens_hsa041102.32981427
8One carbon pool by folate_Homo sapiens_hsa006702.32345669
9Fanconi anemia pathway_Homo sapiens_hsa034602.26851033
10Base excision repair_Homo sapiens_hsa034102.22978425
11Homologous recombination_Homo sapiens_hsa034402.17450200
12Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.06405992
13Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.88183653
14Nucleotide excision repair_Homo sapiens_hsa034201.84163131
15RNA transport_Homo sapiens_hsa030131.77318637
16Ribosome_Homo sapiens_hsa030101.70070303
17Spliceosome_Homo sapiens_hsa030401.65581007
18Transcriptional misregulation in cancer_Homo sapiens_hsa052021.61426036
19p53 signaling pathway_Homo sapiens_hsa041151.31400215
20mRNA surveillance pathway_Homo sapiens_hsa030151.16417076
21Pyrimidine metabolism_Homo sapiens_hsa002401.02503091
22RNA degradation_Homo sapiens_hsa030181.00399409
23Oocyte meiosis_Homo sapiens_hsa041140.97626063
24Selenocompound metabolism_Homo sapiens_hsa004500.95559782
25Basal transcription factors_Homo sapiens_hsa030220.94198351
26MicroRNAs in cancer_Homo sapiens_hsa052060.93822989
27Antigen processing and presentation_Homo sapiens_hsa046120.93203587
28Herpes simplex infection_Homo sapiens_hsa051680.88320477
29Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.86021356
30Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.77160264
31HTLV-I infection_Homo sapiens_hsa051660.76540118
32Small cell lung cancer_Homo sapiens_hsa052220.73160852
33Renin-angiotensin system_Homo sapiens_hsa046140.71524680
34Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.68651650
35Epstein-Barr virus infection_Homo sapiens_hsa051690.64011694
36Apoptosis_Homo sapiens_hsa042100.62930278
37RNA polymerase_Homo sapiens_hsa030200.61050056
38NF-kappa B signaling pathway_Homo sapiens_hsa040640.60304977
39Pentose phosphate pathway_Homo sapiens_hsa000300.60123466
40Asthma_Homo sapiens_hsa053100.56066545
41Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.55871959
42B cell receptor signaling pathway_Homo sapiens_hsa046620.55606902
43Allograft rejection_Homo sapiens_hsa053300.55282190
44Hepatitis B_Homo sapiens_hsa051610.55096125
45Chronic myeloid leukemia_Homo sapiens_hsa052200.54196755
46Hematopoietic cell lineage_Homo sapiens_hsa046400.54164775
47Vitamin B6 metabolism_Homo sapiens_hsa007500.53715660
48Autoimmune thyroid disease_Homo sapiens_hsa053200.50524498
49Legionellosis_Homo sapiens_hsa051340.50221223
50Measles_Homo sapiens_hsa051620.47247895
51Acute myeloid leukemia_Homo sapiens_hsa052210.44836249
52Central carbon metabolism in cancer_Homo sapiens_hsa052300.44484981
53Lysine degradation_Homo sapiens_hsa003100.44451579
54Non-small cell lung cancer_Homo sapiens_hsa052230.44245899
55Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.43373835
56Pancreatic cancer_Homo sapiens_hsa052120.43346532
57Purine metabolism_Homo sapiens_hsa002300.40421866
58Colorectal cancer_Homo sapiens_hsa052100.39910414
59Inositol phosphate metabolism_Homo sapiens_hsa005620.39105979
60Graft-versus-host disease_Homo sapiens_hsa053320.38395438
61Intestinal immune network for IgA production_Homo sapiens_hsa046720.34899118
62Platelet activation_Homo sapiens_hsa046110.34373376
63N-Glycan biosynthesis_Homo sapiens_hsa005100.33787346
64Fructose and mannose metabolism_Homo sapiens_hsa000510.33761483
65Proteasome_Homo sapiens_hsa030500.33266669
66mTOR signaling pathway_Homo sapiens_hsa041500.33141405
67Osteoclast differentiation_Homo sapiens_hsa043800.31694622
68Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.30568530
69Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.30286551
70Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.28417424
71Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.28317957
72Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.28054126
73Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.27784196
74Influenza A_Homo sapiens_hsa051640.27683390
75Basal cell carcinoma_Homo sapiens_hsa052170.27467709
76NOD-like receptor signaling pathway_Homo sapiens_hsa046210.27433136
77Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.27388171
78Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.27132254
79ErbB signaling pathway_Homo sapiens_hsa040120.26799939
80Phosphatidylinositol signaling system_Homo sapiens_hsa040700.26698014
81VEGF signaling pathway_Homo sapiens_hsa043700.25970749
82Primary immunodeficiency_Homo sapiens_hsa053400.25800546
83Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.25349240
84Leishmaniasis_Homo sapiens_hsa051400.25326887
85Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.24959225
86Viral myocarditis_Homo sapiens_hsa054160.24458235
87Longevity regulating pathway - mammal_Homo sapiens_hsa042110.23031086
88Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.22760936
89RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.22516307
90Neurotrophin signaling pathway_Homo sapiens_hsa047220.22268476
91Thyroid hormone signaling pathway_Homo sapiens_hsa049190.21475429
92HIF-1 signaling pathway_Homo sapiens_hsa040660.21347898
93Melanoma_Homo sapiens_hsa052180.21316209
94FoxO signaling pathway_Homo sapiens_hsa040680.21188687
95Galactose metabolism_Homo sapiens_hsa000520.20712435
96Thyroid cancer_Homo sapiens_hsa052160.20637361
97Biosynthesis of amino acids_Homo sapiens_hsa012300.20600833
98Toll-like receptor signaling pathway_Homo sapiens_hsa046200.19510484
99Prostate cancer_Homo sapiens_hsa052150.19260521
100Notch signaling pathway_Homo sapiens_hsa043300.18478163
101Glioma_Homo sapiens_hsa052140.17897570
102Fatty acid biosynthesis_Homo sapiens_hsa000610.17825916
103TGF-beta signaling pathway_Homo sapiens_hsa043500.17600755
104Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.17549613
105Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.17436151
106Carbon metabolism_Homo sapiens_hsa012000.17320301
107Proteoglycans in cancer_Homo sapiens_hsa052050.17201020
108Sulfur relay system_Homo sapiens_hsa041220.17158599
109Type I diabetes mellitus_Homo sapiens_hsa049400.17024740
110Cysteine and methionine metabolism_Homo sapiens_hsa002700.16581055
111TNF signaling pathway_Homo sapiens_hsa046680.16363601
112Tuberculosis_Homo sapiens_hsa051520.16067929
113Prolactin signaling pathway_Homo sapiens_hsa049170.15294758
114Endometrial cancer_Homo sapiens_hsa052130.14883029
115Drug metabolism - other enzymes_Homo sapiens_hsa009830.14731752
116Pathways in cancer_Homo sapiens_hsa052000.14250666
117Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.14158778
118Toxoplasmosis_Homo sapiens_hsa051450.13965704
119Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.13951089
120Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.13746269
121Carbohydrate digestion and absorption_Homo sapiens_hsa049730.13146252
122Folate biosynthesis_Homo sapiens_hsa007900.12385276
123Leukocyte transendothelial migration_Homo sapiens_hsa046700.12248381
124Bladder cancer_Homo sapiens_hsa052190.12087350
125T cell receptor signaling pathway_Homo sapiens_hsa046600.09496483

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »