Rank | Gene Set | Z-score |
---|---|---|
1 | antibacterial humoral response (GO:0019731) | 9.64545186 |
2 | organ or tissue specific immune response (GO:0002251) | 9.24539400 |
3 | antimicrobial humoral response (GO:0019730) | 8.85280785 |
4 | DNA replication-dependent nucleosome assembly (GO:0006335) | 8.68554421 |
5 | DNA replication-dependent nucleosome organization (GO:0034723) | 8.68554421 |
6 | nucleosome assembly (GO:0006334) | 8.13390800 |
7 | chromatin assembly (GO:0031497) | 7.97241564 |
8 | nuclear pore complex assembly (GO:0051292) | 7.25686685 |
9 | protein-DNA complex assembly (GO:0065004) | 6.91103976 |
10 | nucleosome organization (GO:0034728) | 6.82276107 |
11 | nuclear pore organization (GO:0006999) | 6.49430484 |
12 | protein-DNA complex subunit organization (GO:0071824) | 5.97189525 |
13 | regulation of histone H3-K9 methylation (GO:0051570) | 5.65678093 |
14 | pore complex assembly (GO:0046931) | 5.48950548 |
15 | chromatin assembly or disassembly (GO:0006333) | 5.37493774 |
16 | DNA unwinding involved in DNA replication (GO:0006268) | 5.37296517 |
17 | DNA replication initiation (GO:0006270) | 4.99962287 |
18 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.81502500 |
19 | DNA strand elongation (GO:0022616) | 4.63898212 |
20 | protein localization to chromosome, centromeric region (GO:0071459) | 4.37281860 |
21 | mitotic chromosome condensation (GO:0007076) | 4.33407213 |
22 | defense response to Gram-positive bacterium (GO:0050830) | 4.26427301 |
23 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.24027498 |
24 | mitotic sister chromatid segregation (GO:0000070) | 4.01879750 |
25 | sister chromatid segregation (GO:0000819) | 3.98296981 |
26 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 3.94144208 |
27 | telomere maintenance via recombination (GO:0000722) | 3.85021091 |
28 | DNA duplex unwinding (GO:0032508) | 3.83532205 |
29 | DNA geometric change (GO:0032392) | 3.69655365 |
30 | V(D)J recombination (GO:0033151) | 3.67131699 |
31 | mitotic recombination (GO:0006312) | 3.61570197 |
32 | viral mRNA export from host cell nucleus (GO:0046784) | 3.60659451 |
33 | mitotic nuclear envelope disassembly (GO:0007077) | 3.47481526 |
34 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.44044789 |
35 | mitotic sister chromatid cohesion (GO:0007064) | 3.39236763 |
36 | DNA synthesis involved in DNA repair (GO:0000731) | 3.37686151 |
37 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.35124854 |
38 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.35124854 |
39 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.35124854 |
40 | regulation of centrosome cycle (GO:0046605) | 3.24167044 |
41 | membrane disassembly (GO:0030397) | 3.24143100 |
42 | nuclear envelope disassembly (GO:0051081) | 3.24143100 |
43 | regulation of megakaryocyte differentiation (GO:0045652) | 3.24112245 |
44 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.22144113 |
45 | CENP-A containing nucleosome assembly (GO:0034080) | 3.21919191 |
46 | positive regulation of chromosome segregation (GO:0051984) | 3.20162692 |
47 | histone lysine demethylation (GO:0070076) | 3.20019117 |
48 | mature B cell differentiation involved in immune response (GO:0002313) | 3.15859336 |
49 | histone demethylation (GO:0016577) | 3.15694042 |
50 | chromatin remodeling at centromere (GO:0031055) | 3.15593008 |
51 | B cell receptor signaling pathway (GO:0050853) | 3.12079841 |
52 | regulation of translational fidelity (GO:0006450) | 3.10110881 |
53 | DNA conformation change (GO:0071103) | 3.07958429 |
54 | telomere organization (GO:0032200) | 3.06198709 |
55 | protein localization to kinetochore (GO:0034501) | 3.05212883 |
56 | telomere maintenance (GO:0000723) | 3.04373415 |
57 | regulation of sister chromatid cohesion (GO:0007063) | 3.03779223 |
58 | regulation of gene silencing (GO:0060968) | 3.00214186 |
59 | peptidyl-lysine dimethylation (GO:0018027) | 2.99727413 |
60 | positive regulation of transcription from RNA polymerase III promoter (GO:0045945) | 2.98354350 |
61 | regulation of centrosome duplication (GO:0010824) | 2.96969742 |
62 | replicative senescence (GO:0090399) | 2.94844912 |
63 | negative regulation of DNA repair (GO:0045738) | 2.91164779 |
64 | embryonic process involved in female pregnancy (GO:0060136) | 2.86039725 |
65 | histone H3-K36 demethylation (GO:0070544) | 2.84403676 |
66 | negative regulation of B cell apoptotic process (GO:0002903) | 2.83749389 |
67 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.83450795 |
68 | non-recombinational repair (GO:0000726) | 2.83450795 |
69 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 2.81457977 |
70 | histone phosphorylation (GO:0016572) | 2.81364542 |
71 | protein demethylation (GO:0006482) | 2.80739452 |
72 | protein dealkylation (GO:0008214) | 2.80739452 |
73 | DNA replication checkpoint (GO:0000076) | 2.75801167 |
74 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 2.75746638 |
75 | regulation of chromosome segregation (GO:0051983) | 2.74799210 |
76 | meiotic chromosome segregation (GO:0045132) | 2.73213840 |
77 | B cell proliferation (GO:0042100) | 2.73205886 |
78 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 2.71625191 |
79 | mRNA cleavage (GO:0006379) | 2.71194427 |
80 | chromosome condensation (GO:0030261) | 2.69829303 |
81 | telomere maintenance via telomere lengthening (GO:0010833) | 2.69797833 |
82 | mitochondrial DNA metabolic process (GO:0032042) | 2.69452658 |
83 | rRNA transcription (GO:0009303) | 2.68853323 |
84 | mature B cell differentiation (GO:0002335) | 2.68423939 |
85 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 2.61785414 |
86 | somatic cell DNA recombination (GO:0016444) | 2.61722928 |
87 | somatic diversification of immune receptors via germline recombination within a single locus (GO:000 | 2.61722928 |
88 | dosage compensation (GO:0007549) | 2.61127433 |
89 | regulation of RNA export from nucleus (GO:0046831) | 2.57867137 |
90 | translesion synthesis (GO:0019985) | 2.57020349 |
91 | regulation of DNA damage checkpoint (GO:2000001) | 2.54180262 |
92 | nuclear envelope organization (GO:0006998) | 2.54039940 |
93 | positive regulation of DNA-templated transcription, initiation (GO:2000144) | 2.51935196 |
94 | regulation of sister chromatid segregation (GO:0033045) | 2.51790388 |
95 | regulation of mitotic sister chromatid separation (GO:0010965) | 2.51790388 |
96 | regulation of mitotic sister chromatid segregation (GO:0033047) | 2.51790388 |
97 | T cell lineage commitment (GO:0002360) | 2.51067820 |
98 | positive regulation of cell cycle checkpoint (GO:1901978) | 2.50542439 |
99 | innate immune response in mucosa (GO:0002227) | 12.2495618 |
100 | mucosal immune response (GO:0002385) | 10.0840413 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.52710132 |
2 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.34095711 |
3 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 4.23974837 |
4 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 4.16512356 |
5 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.48377993 |
6 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 2.81673727 |
7 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.66631707 |
8 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 2.55590258 |
9 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.49256880 |
10 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.22869346 |
11 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 2.18218129 |
12 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 2.13770399 |
13 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.05588121 |
14 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 16.9155495 |
15 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.86569501 |
16 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.83163761 |
17 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.82815706 |
18 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.73525583 |
19 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.57162361 |
20 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.50057661 |
21 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.48318186 |
22 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.43347960 |
23 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.42060993 |
24 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.37939649 |
25 | MYC_22102868_ChIP-Seq_BL_Human | 1.37763195 |
26 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.37220548 |
27 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.36811361 |
28 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.36043233 |
29 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.35298600 |
30 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.32931709 |
31 | GATA1_22025678_ChIP-Seq_K562_Human | 1.29263684 |
32 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.26397284 |
33 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.25805378 |
34 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.19096614 |
35 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.18172934 |
36 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.17864494 |
37 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.17554276 |
38 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.14851650 |
39 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.13566518 |
40 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.13555822 |
41 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.11479377 |
42 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.09585363 |
43 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.09212329 |
44 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.08658150 |
45 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.07552529 |
46 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.05017652 |
47 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.04987784 |
48 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.04582902 |
49 | ETS1_22383799_ChIP-Seq_G1ME_Mouse | 1.04010992 |
50 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.01911733 |
51 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.00457782 |
52 | * MAF_26560356_Chip-Seq_TH1_Human | 0.98969940 |
53 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.96470255 |
54 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.94523066 |
55 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.93438332 |
56 | SOX2_18692474_ChIP-Seq_MESCs_Mouse | 0.91287169 |
57 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.90379670 |
58 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.89969781 |
59 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.87492889 |
60 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.86251108 |
61 | MYB_26560356_Chip-Seq_TH1_Human | 0.84829138 |
62 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.81741933 |
63 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.80612863 |
64 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.80440342 |
65 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.78858323 |
66 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.77103670 |
67 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.76455434 |
68 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.74709278 |
69 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.72635638 |
70 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.71753583 |
71 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.71741276 |
72 | VDR_24763502_ChIP-Seq_THP-1_Human | 0.71209419 |
73 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.71075043 |
74 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.70148423 |
75 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.70144732 |
76 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.68713727 |
77 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.68389842 |
78 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.68004847 |
79 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.67779466 |
80 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.66455441 |
81 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.66360995 |
82 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.65305554 |
83 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 0.65049022 |
84 | MYB_26560356_Chip-Seq_TH2_Human | 0.64511296 |
85 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 0.63944393 |
86 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.63208685 |
87 | UTX_26944678_Chip-Seq_JUKART_Human | 0.63108493 |
88 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.61037985 |
89 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.61015742 |
90 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 0.60439686 |
91 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.60415757 |
92 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.60013928 |
93 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.59509566 |
94 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.58298405 |
95 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.57964194 |
96 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.57941895 |
97 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.57007353 |
98 | SCL_19346495_ChIP-Seq_HPC-7_Human | 0.56061379 |
99 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.54615862 |
100 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.53387800 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008057_abnormal_DNA_replication | 5.41313121 |
2 | MP0010094_abnormal_chromosome_stability | 4.82251544 |
3 | MP0003111_abnormal_nucleus_morphology | 3.81154360 |
4 | MP0003077_abnormal_cell_cycle | 3.71501310 |
5 | MP0002009_preneoplasia | 3.44838191 |
6 | MP0003693_abnormal_embryo_hatching | 3.35342854 |
7 | MP0010352_gastrointestinal_tract_polyps | 2.95876782 |
8 | MP0004957_abnormal_blastocyst_morpholog | 2.76380831 |
9 | MP0002166_altered_tumor_susceptibility | 2.74544817 |
10 | MP0002396_abnormal_hematopoietic_system | 2.74022064 |
11 | MP0003763_abnormal_thymus_physiology | 2.69736980 |
12 | MP0008007_abnormal_cellular_replicative | 2.42202096 |
13 | MP0010234_abnormal_vibrissa_follicle | 2.34986876 |
14 | MP0000685_abnormal_immune_system | 2.25641485 |
15 | MP0010307_abnormal_tumor_latency | 2.23366170 |
16 | MP0001661_extended_life_span | 2.16464533 |
17 | MP0004808_abnormal_hematopoietic_stem | 2.13200265 |
18 | MP0002006_tumorigenesis | 2.07301267 |
19 | MP0008058_abnormal_DNA_repair | 2.06062243 |
20 | MP0000350_abnormal_cell_proliferation | 1.93385461 |
21 | MP0005076_abnormal_cell_differentiation | 1.88437036 |
22 | MP0001835_abnormal_antigen_presentation | 1.85916622 |
23 | MP0008932_abnormal_embryonic_tissue | 1.85383796 |
24 | MP0009697_abnormal_copulation | 1.77794877 |
25 | MP0004381_abnormal_hair_follicle | 1.61316023 |
26 | MP0004185_abnormal_adipocyte_glucose | 1.59153335 |
27 | MP0000703_abnormal_thymus_morphology | 1.59043290 |
28 | MP0003786_premature_aging | 1.57311662 |
29 | MP0002877_abnormal_melanocyte_morpholog | 1.56570830 |
30 | MP0002398_abnormal_bone_marrow | 1.55102618 |
31 | MP0001800_abnormal_humoral_immune | 1.47040727 |
32 | MP0005645_abnormal_hypothalamus_physiol | 1.43533537 |
33 | MP0002722_abnormal_immune_system | 1.42222495 |
34 | MP0005623_abnormal_meninges_morphology | 1.40443446 |
35 | MP0002019_abnormal_tumor_incidence | 1.38568773 |
36 | MP0000313_abnormal_cell_death | 1.35502094 |
37 | MP0000490_abnormal_crypts_of | 1.34671156 |
38 | MP0000569_abnormal_digit_pigmentation | 1.33754843 |
39 | MP0001730_embryonic_growth_arrest | 1.28409632 |
40 | MP0002086_abnormal_extraembryonic_tissu | 1.26589554 |
41 | MP0000537_abnormal_urethra_morphology | 1.25061573 |
42 | MP0001672_abnormal_embryogenesis/_devel | 1.24582060 |
43 | MP0005380_embryogenesis_phenotype | 1.24582060 |
44 | MP0003984_embryonic_growth_retardation | 1.21669579 |
45 | MP0000689_abnormal_spleen_morphology | 1.18336095 |
46 | MP0002088_abnormal_embryonic_growth/wei | 1.17798190 |
47 | MP0001849_ear_inflammation | 1.17687933 |
48 | MP0005220_abnormal_exocrine_pancreas | 1.16858030 |
49 | MP0002163_abnormal_gland_morphology | 1.15805784 |
50 | MP0002080_prenatal_lethality | 1.10764498 |
51 | MP0005671_abnormal_response_to | 1.10577688 |
52 | MP0001697_abnormal_embryo_size | 1.08437238 |
53 | MP0004233_abnormal_muscle_weight | 1.06352208 |
54 | MP0002429_abnormal_blood_cell | 1.04367882 |
55 | MP0000716_abnormal_immune_system | 1.02646167 |
56 | MP0002160_abnormal_reproductive_system | 1.02345123 |
57 | MP0003705_abnormal_hypodermis_morpholog | 0.96025851 |
58 | MP0002420_abnormal_adaptive_immunity | 0.95083727 |
59 | MP0000733_abnormal_muscle_development | 0.92085043 |
60 | MP0000015_abnormal_ear_pigmentation | 0.92082211 |
61 | MP0002138_abnormal_hepatobiliary_system | 0.91665481 |
62 | MP0001819_abnormal_immune_cell | 0.91211002 |
63 | MP0004947_skin_inflammation | 0.91161959 |
64 | MP0005621_abnormal_cell_physiology | 0.91061851 |
65 | MP0002452_abnormal_antigen_presenting | 0.89314008 |
66 | MP0002084_abnormal_developmental_patter | 0.88638823 |
67 | MP0005000_abnormal_immune_tolerance | 0.87525990 |
68 | MP0001790_abnormal_immune_system | 0.86986506 |
69 | MP0005387_immune_system_phenotype | 0.86986506 |
70 | MP0006035_abnormal_mitochondrial_morpho | 0.86226959 |
71 | MP0005310_abnormal_salivary_gland | 0.85952608 |
72 | MP0009278_abnormal_bone_marrow | 0.84124004 |
73 | MP0000358_abnormal_cell_content/ | 0.84120494 |
74 | MP0002085_abnormal_embryonic_tissue | 0.83597796 |
75 | MP0005384_cellular_phenotype | 0.82803103 |
76 | MP0003315_abnormal_perineum_morphology | 0.81311769 |
77 | MP0003300_gastrointestinal_ulcer | 0.80358303 |
78 | MP0002723_abnormal_immune_serum | 0.79048170 |
79 | MP0004197_abnormal_fetal_growth/weight/ | 0.78800176 |
80 | MP0005647_abnormal_sex_gland | 0.78620795 |
81 | MP0002092_abnormal_eye_morphology | 0.78605846 |
82 | MP0005451_abnormal_body_composition | 0.78101201 |
83 | MP0003091_abnormal_cell_migration | 0.73604217 |
84 | MP0001346_abnormal_lacrimal_gland | 0.72250256 |
85 | MP0005397_hematopoietic_system_phenotyp | 0.69556950 |
86 | MP0001545_abnormal_hematopoietic_system | 0.69556950 |
87 | MP0003718_maternal_effect | 0.68196306 |
88 | MP0001929_abnormal_gametogenesis | 0.66218723 |
89 | MP0003656_abnormal_erythrocyte_physiolo | 0.65406376 |
90 | MP0001915_intracranial_hemorrhage | 0.62572113 |
91 | MP0001879_abnormal_lymphatic_vessel | 0.61573551 |
92 | MP0003453_abnormal_keratinocyte_physiol | 0.61405277 |
93 | MP0003937_abnormal_limbs/digits/tail_de | 0.59282952 |
94 | MP0002697_abnormal_eye_size | 0.59090597 |
95 | MP0001727_abnormal_embryo_implantation | 0.59087370 |
96 | MP0000477_abnormal_intestine_morphology | 0.58853669 |
97 | MP0005187_abnormal_penis_morphology | 0.58095155 |
98 | MP0002405_respiratory_system_inflammati | 0.58089424 |
99 | MP0009931_abnormal_skin_appearance | 0.57791165 |
100 | MP0003221_abnormal_cardiomyocyte_apopto | 0.56473138 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 5.87318701 |
2 | IgM deficiency (HP:0002850) | 5.79934558 |
3 | IgA deficiency (HP:0002720) | 5.58540075 |
4 | Chromsome breakage (HP:0040012) | 5.33929247 |
5 | Colitis (HP:0002583) | 4.78040775 |
6 | Abnormality of chromosome stability (HP:0003220) | 3.44011368 |
7 | Gastrointestinal stroma tumor (HP:0100723) | 3.43860360 |
8 | Squamous cell carcinoma (HP:0002860) | 3.35275901 |
9 | Thyroiditis (HP:0100646) | 3.31107100 |
10 | Cellulitis (HP:0100658) | 3.28102493 |
11 | Abnormality of the fingertips (HP:0001211) | 3.12470695 |
12 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 3.05235553 |
13 | Abnormality of the preputium (HP:0100587) | 2.96542584 |
14 | B lymphocytopenia (HP:0010976) | 2.93808175 |
15 | Clubbing of toes (HP:0100760) | 2.89961308 |
16 | Abnormality of the ileum (HP:0001549) | 2.86175459 |
17 | Acute lymphatic leukemia (HP:0006721) | 2.85753539 |
18 | Inflammation of the large intestine (HP:0002037) | 2.74959573 |
19 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.73607546 |
20 | Recurrent sinusitis (HP:0011108) | 2.70662717 |
21 | Recurrent bronchitis (HP:0002837) | 2.69476550 |
22 | Recurrent viral infections (HP:0004429) | 2.67500051 |
23 | Meckel diverticulum (HP:0002245) | 2.66929347 |
24 | Abnormality of the carotid arteries (HP:0005344) | 2.65906367 |
25 | Medulloblastoma (HP:0002885) | 2.61145863 |
26 | Gastrointestinal inflammation (HP:0004386) | 2.57819663 |
27 | Prominent nose (HP:0000448) | 2.57753785 |
28 | Embryonal renal neoplasm (HP:0011794) | 2.52792781 |
29 | Lymphopenia (HP:0001888) | 2.52765745 |
30 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.51025661 |
31 | Basal cell carcinoma (HP:0002671) | 2.46986205 |
32 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.46393952 |
33 | Birth length less than 3rd percentile (HP:0003561) | 2.42954617 |
34 | Abnormality of B cell number (HP:0010975) | 2.42767860 |
35 | Agammaglobulinemia (HP:0004432) | 2.39519550 |
36 | Viral hepatitis (HP:0006562) | 2.36460947 |
37 | Abnormality of DNA repair (HP:0003254) | 2.35685480 |
38 | Lymphoma (HP:0002665) | 2.29798885 |
39 | Subacute progressive viral hepatitis (HP:0006572) | 2.23969372 |
40 | Cafe-au-lait spot (HP:0000957) | 2.23903803 |
41 | Chronic diarrhea (HP:0002028) | 2.22377468 |
42 | Small intestinal stenosis (HP:0012848) | 2.18820167 |
43 | Duodenal stenosis (HP:0100867) | 2.18820167 |
44 | Myelodysplasia (HP:0002863) | 2.18774658 |
45 | Prostate neoplasm (HP:0100787) | 2.17568484 |
46 | Reticulocytopenia (HP:0001896) | 2.16937114 |
47 | Abnormality of pyrimidine metabolism (HP:0004353) | 2.15712670 |
48 | Erythema (HP:0010783) | 2.15340647 |
49 | Duplicated collecting system (HP:0000081) | 2.14471758 |
50 | Hepatitis (HP:0012115) | 2.12890571 |
51 | Panhypogammaglobulinemia (HP:0003139) | 2.10988547 |
52 | Hyperacusis (HP:0010780) | 2.10536326 |
53 | Microvesicular hepatic steatosis (HP:0001414) | 2.09810743 |
54 | Interstitial pulmonary disease (HP:0006530) | 2.08379337 |
55 | Leukopenia (HP:0001882) | 2.06789581 |
56 | 11 pairs of ribs (HP:0000878) | 2.06616463 |
57 | Meningitis (HP:0001287) | 2.05147393 |
58 | Orthostatic hypotension (HP:0001278) | 2.05020762 |
59 | Ureteral duplication (HP:0000073) | 2.04647499 |
60 | Sandal gap (HP:0001852) | 2.03339447 |
61 | Hypergonadotropic hypogonadism (HP:0000815) | 2.02064357 |
62 | Autoimmune hemolytic anemia (HP:0001890) | 1.99185399 |
63 | Osteomyelitis (HP:0002754) | 1.97801150 |
64 | Deep philtrum (HP:0002002) | 1.97631859 |
65 | Dry hair (HP:0011359) | 1.97172470 |
66 | Hypoplasia of the thymus (HP:0000778) | 1.96626593 |
67 | Arteriovenous malformation (HP:0100026) | 1.96373675 |
68 | Abnormality of the columella (HP:0009929) | 1.92959414 |
69 | Abnormality of T cell physiology (HP:0011840) | 1.89489539 |
70 | Emphysema (HP:0002097) | 1.88671595 |
71 | High anterior hairline (HP:0009890) | 1.88198860 |
72 | Ectopic kidney (HP:0000086) | 1.87456034 |
73 | Micronodular cirrhosis (HP:0001413) | 1.86615905 |
74 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.86232138 |
75 | Syringomyelia (HP:0003396) | 1.86117866 |
76 | Spinal cord lesions (HP:0100561) | 1.86117866 |
77 | Deep palmar crease (HP:0006191) | 1.85555673 |
78 | Short thumb (HP:0009778) | 1.82991003 |
79 | Lower limb hyperreflexia (HP:0002395) | 1.81443634 |
80 | High pitched voice (HP:0001620) | 1.80912820 |
81 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.80235822 |
82 | Absent radius (HP:0003974) | 1.80179850 |
83 | Recurrent bacterial skin infections (HP:0005406) | 1.79885251 |
84 | Sloping forehead (HP:0000340) | 1.79533843 |
85 | Abnormality of chromosome segregation (HP:0002916) | 1.78983164 |
86 | Asymmetry of the thorax (HP:0001555) | 1.77829702 |
87 | Embryonal neoplasm (HP:0002898) | 1.77761378 |
88 | Mediastinal lymphadenopathy (HP:0100721) | 1.77658817 |
89 | Bone marrow hypocellularity (HP:0005528) | 1.77449280 |
90 | Abnormality of the duodenum (HP:0002246) | 1.77224479 |
91 | Large eyes (HP:0001090) | 1.75949686 |
92 | Abnormality of the renal collecting system (HP:0004742) | 1.75845698 |
93 | Renovascular hypertension (HP:0100817) | 1.74106330 |
94 | Combined immunodeficiency (HP:0005387) | 1.73285505 |
95 | Carpal bone hypoplasia (HP:0001498) | 1.73248545 |
96 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.71924896 |
97 | Anal stenosis (HP:0002025) | 1.70781795 |
98 | Absent thumb (HP:0009777) | 1.70456953 |
99 | Progressive muscle weakness (HP:0003323) | 1.69530327 |
100 | IgG deficiency (HP:0004315) | 1.69081156 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ZAK | 9.19103072 |
2 | TLK1 | 8.90672755 |
3 | VRK1 | 5.35971320 |
4 | RPS6KA5 | 3.29305299 |
5 | DAPK3 | 2.53794212 |
6 | STK4 | 1.96504776 |
7 | AURKA | 1.89807301 |
8 | SMG1 | 1.87723833 |
9 | CDC7 | 1.80663840 |
10 | EEF2K | 1.66140882 |
11 | BUB1 | 1.51323494 |
12 | CHEK2 | 1.41331677 |
13 | CDK12 | 1.40210915 |
14 | AURKB | 1.31064335 |
15 | PIM1 | 1.30082414 |
16 | SCYL2 | 1.25076356 |
17 | TRIB3 | 1.24463162 |
18 | TAF1 | 1.12644559 |
19 | MAP3K10 | 1.08629258 |
20 | PKN1 | 1.08394233 |
21 | ICK | 1.02754171 |
22 | RPS6KB2 | 0.91680556 |
23 | NME2 | 0.85209027 |
24 | PBK | 0.82959963 |
25 | MAP3K8 | 0.81489373 |
26 | SRPK1 | 0.79388252 |
27 | TTK | 0.78606787 |
28 | BTK | 0.77749913 |
29 | BRSK2 | 0.76374378 |
30 | ATR | 0.75717995 |
31 | BLK | 0.75326173 |
32 | CAMK1D | 0.70840735 |
33 | MELK | 0.64493629 |
34 | IRAK4 | 0.63419476 |
35 | NLK | 0.63065162 |
36 | MAPK11 | 0.62225341 |
37 | BRAF | 0.62178776 |
38 | PRKAA1 | 0.59662015 |
39 | CDK8 | 0.58595296 |
40 | NEK2 | 0.58539452 |
41 | AKT2 | 0.58014846 |
42 | CDK7 | 0.57965505 |
43 | EIF2AK3 | 0.52961902 |
44 | CSNK1A1L | 0.52256881 |
45 | PKN2 | 0.51877825 |
46 | MARK3 | 0.51190955 |
47 | BRD4 | 0.50269815 |
48 | CCNB1 | 0.49037032 |
49 | NEK1 | 0.49019149 |
50 | CHEK1 | 0.48635040 |
51 | CDK6 | 0.47865889 |
52 | PLK1 | 0.46123126 |
53 | MAP2K7 | 0.44671693 |
54 | ATM | 0.42760069 |
55 | CAMK1G | 0.42735545 |
56 | CSNK1G3 | 0.42478333 |
57 | WEE1 | 0.42018884 |
58 | SYK | 0.41189117 |
59 | CDK4 | 0.40664784 |
60 | MAP2K3 | 0.38420121 |
61 | JAK2 | 0.36384505 |
62 | PRKCQ | 0.36305359 |
63 | CSNK1G1 | 0.35474685 |
64 | PLK4 | 0.34322182 |
65 | CAMK4 | 0.32563395 |
66 | IRAK2 | 0.32493341 |
67 | MTOR | 0.31269287 |
68 | PRPF4B | 0.30845237 |
69 | MAP3K13 | 0.30693043 |
70 | TSSK6 | 0.29354521 |
71 | CDK2 | 0.29149008 |
72 | RAF1 | 0.28482749 |
73 | TRPM7 | 0.27838660 |
74 | NEK9 | 0.27016423 |
75 | CDK9 | 0.25256044 |
76 | RPS6KB1 | 0.24938752 |
77 | STK16 | 0.24906392 |
78 | PIK3CG | 0.24870516 |
79 | MAP3K2 | 0.24045399 |
80 | AKT3 | 0.23124423 |
81 | CDK1 | 0.23103474 |
82 | MST1R | 0.21272022 |
83 | PAK1 | 0.20951057 |
84 | MAPKAPK5 | 0.18534163 |
85 | TTN | 0.17880700 |
86 | IRAK3 | 0.16116834 |
87 | RPS6KA1 | 0.15725015 |
88 | RET | 0.14266665 |
89 | LYN | 0.13810178 |
90 | MAP2K2 | 0.13342075 |
91 | MAP4K1 | 0.13022923 |
92 | PLK3 | 0.12588609 |
93 | MAP3K14 | 0.12068215 |
94 | RPS6KA4 | 0.11246557 |
95 | FGFR3 | 0.11132028 |
96 | RPS6KL1 | 0.11100723 |
97 | RPS6KC1 | 0.11100723 |
98 | KSR2 | 0.11026148 |
99 | STK10 | 0.10469249 |
100 | BRSK1 | 0.10111220 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * Alcoholism_Homo sapiens_hsa05034 | 8.05340326 |
2 | * Viral carcinogenesis_Homo sapiens_hsa05203 | 3.67468789 |
3 | DNA replication_Homo sapiens_hsa03030 | 2.55503175 |
4 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 2.09883143 |
5 | * Systemic lupus erythematosus_Homo sapiens_hsa05322 | 11.4615041 |
6 | Mismatch repair_Homo sapiens_hsa03430 | 1.46644484 |
7 | Cell cycle_Homo sapiens_hsa04110 | 1.36077744 |
8 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.19149091 |
9 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.19077360 |
10 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.15762222 |
11 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.10292355 |
12 | Homologous recombination_Homo sapiens_hsa03440 | 1.06125559 |
13 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.05431271 |
14 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.02521201 |
15 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.99331335 |
16 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.93354503 |
17 | Base excision repair_Homo sapiens_hsa03410 | 0.92602849 |
18 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.88625929 |
19 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.79091661 |
20 | Asthma_Homo sapiens_hsa05310 | 0.71699137 |
21 | Allograft rejection_Homo sapiens_hsa05330 | 0.70083600 |
22 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.66051399 |
23 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.64883730 |
24 | RNA transport_Homo sapiens_hsa03013 | 0.61846754 |
25 | Glioma_Homo sapiens_hsa05214 | 0.61395073 |
26 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.61197359 |
27 | Thyroid cancer_Homo sapiens_hsa05216 | 0.60838960 |
28 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.60371804 |
29 | HTLV-I infection_Homo sapiens_hsa05166 | 0.60182363 |
30 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.58225778 |
31 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.54907714 |
32 | Leishmaniasis_Homo sapiens_hsa05140 | 0.53998433 |
33 | Spliceosome_Homo sapiens_hsa03040 | 0.53387466 |
34 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.53049110 |
35 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.51282734 |
36 | Sulfur relay system_Homo sapiens_hsa04122 | 0.49087436 |
37 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.48925721 |
38 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.48894305 |
39 | Hepatitis B_Homo sapiens_hsa05161 | 0.48717788 |
40 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.47360789 |
41 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.47299595 |
42 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.45878159 |
43 | Bladder cancer_Homo sapiens_hsa05219 | 0.45515094 |
44 | Prostate cancer_Homo sapiens_hsa05215 | 0.45183442 |
45 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.44549412 |
46 | Colorectal cancer_Homo sapiens_hsa05210 | 0.44374064 |
47 | Viral myocarditis_Homo sapiens_hsa05416 | 0.44069628 |
48 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.43583891 |
49 | Apoptosis_Homo sapiens_hsa04210 | 0.43539682 |
50 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.43284954 |
51 | Endometrial cancer_Homo sapiens_hsa05213 | 0.42757848 |
52 | Influenza A_Homo sapiens_hsa05164 | 0.42546814 |
53 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.42477600 |
54 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.42438412 |
55 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.38856223 |
56 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.38751558 |
57 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.37969072 |
58 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.36882312 |
59 | Measles_Homo sapiens_hsa05162 | 0.36555669 |
60 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.33684864 |
61 | Lysine degradation_Homo sapiens_hsa00310 | 0.33523468 |
62 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.32395161 |
63 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.31351640 |
64 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.30936148 |
65 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.29785973 |
66 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.29365194 |
67 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.29196618 |
68 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.28918981 |
69 | Purine metabolism_Homo sapiens_hsa00230 | 0.28059643 |
70 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.26192128 |
71 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.25972756 |
72 | Melanoma_Homo sapiens_hsa05218 | 0.25657278 |
73 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.24847603 |
74 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.23932589 |
75 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.23324524 |
76 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.23060306 |
77 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.21564667 |
78 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.21446566 |
79 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.20423120 |
80 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.20334802 |
81 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.19518358 |
82 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.18039190 |
83 | RNA degradation_Homo sapiens_hsa03018 | 0.18000380 |
84 | RNA polymerase_Homo sapiens_hsa03020 | 0.17440456 |
85 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.17139800 |
86 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.16349265 |
87 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.15982873 |
88 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.15436129 |
89 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.15008954 |
90 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.14688827 |
91 | Ribosome_Homo sapiens_hsa03010 | 0.13909505 |
92 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.13694532 |
93 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.13353700 |
94 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.12672728 |
95 | Galactose metabolism_Homo sapiens_hsa00052 | 0.12415444 |
96 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.11962862 |
97 | Tuberculosis_Homo sapiens_hsa05152 | 0.11508889 |
98 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.11203769 |
99 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.09966881 |
100 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.09165452 |