Rank | Gene Set | Z-score |
---|---|---|
1 | melanin biosynthetic process (GO:0042438) | 6.69673595 |
2 | melanin metabolic process (GO:0006582) | 6.08507651 |
3 | COPI coating of Golgi vesicle (GO:0048205) | 5.20282139 |
4 | Golgi transport vesicle coating (GO:0048200) | 5.20282139 |
5 | secondary metabolite biosynthetic process (GO:0044550) | 5.12429212 |
6 | DNA deamination (GO:0045006) | 4.54553232 |
7 | viral transcription (GO:0019083) | 4.35517374 |
8 | ribosomal small subunit assembly (GO:0000028) | 4.28872273 |
9 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 4.25177751 |
10 | translational termination (GO:0006415) | 4.12651556 |
11 | amyloid precursor protein catabolic process (GO:0042987) | 3.88628939 |
12 | barbed-end actin filament capping (GO:0051016) | 3.88581024 |
13 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 3.77435643 |
14 | translational elongation (GO:0006414) | 3.73697314 |
15 | protein retention in ER lumen (GO:0006621) | 3.73325752 |
16 | pinocytosis (GO:0006907) | 3.61892020 |
17 | GDP-mannose metabolic process (GO:0019673) | 3.61104786 |
18 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.50341324 |
19 | mannose metabolic process (GO:0006013) | 3.48561217 |
20 | ribosomal small subunit biogenesis (GO:0042274) | 3.48172349 |
21 | protein maturation by protein folding (GO:0022417) | 3.43679823 |
22 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.40865268 |
23 | UV protection (GO:0009650) | 3.38742253 |
24 | protein targeting to ER (GO:0045047) | 3.36162045 |
25 | viral life cycle (GO:0019058) | 3.29681662 |
26 | mitotic nuclear envelope reassembly (GO:0007084) | 3.27577756 |
27 | nuclear envelope reassembly (GO:0031468) | 3.27577756 |
28 | translational initiation (GO:0006413) | 3.24372704 |
29 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.24286635 |
30 | cotranslational protein targeting to membrane (GO:0006613) | 3.23382123 |
31 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.18108727 |
32 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.16605207 |
33 | melanocyte differentiation (GO:0030318) | 3.15886961 |
34 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 3.14251719 |
35 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.11161562 |
36 | response to thyroid hormone (GO:0097066) | 3.09738412 |
37 | protein localization to endoplasmic reticulum (GO:0070972) | 3.09182085 |
38 | pigment cell differentiation (GO:0050931) | 3.06965000 |
39 | pentose metabolic process (GO:0019321) | 3.04979043 |
40 | epithelial cell-cell adhesion (GO:0090136) | 3.02141765 |
41 | cellular protein complex disassembly (GO:0043624) | 3.00554441 |
42 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 2.94934980 |
43 | protein localization to endosome (GO:0036010) | 2.93821042 |
44 | glycosphingolipid catabolic process (GO:0046479) | 2.92743482 |
45 | cellular response to thyroid hormone stimulus (GO:0097067) | 2.91998663 |
46 | regulation of early endosome to late endosome transport (GO:2000641) | 2.90315775 |
47 | pentose-phosphate shunt (GO:0006098) | 2.87502156 |
48 | ribosomal large subunit biogenesis (GO:0042273) | 2.84454519 |
49 | positive regulation of odontogenesis (GO:0042482) | 2.83241336 |
50 | maternal placenta development (GO:0001893) | 2.82838277 |
51 | tyrosine metabolic process (GO:0006570) | 2.81386354 |
52 | glucose 6-phosphate metabolic process (GO:0051156) | 2.80668411 |
53 | protein complex disassembly (GO:0043241) | 2.76150814 |
54 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 2.75875766 |
55 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.75875766 |
56 | positive regulation of keratinocyte differentiation (GO:0045618) | 2.75135879 |
57 | formation of translation preinitiation complex (GO:0001731) | 2.74889578 |
58 | maturation of SSU-rRNA (GO:0030490) | 2.74850913 |
59 | negative regulation of release of cytochrome c from mitochondria (GO:0090201) | 2.73833790 |
60 | heterochromatin organization (GO:0070828) | 2.70934998 |
61 | ncRNA 3-end processing (GO:0043628) | 2.70471782 |
62 | semaphorin-plexin signaling pathway (GO:0071526) | 2.68599664 |
63 | glycolipid catabolic process (GO:0019377) | 2.56983794 |
64 | intracellular estrogen receptor signaling pathway (GO:0030520) | 2.55200218 |
65 | endothelial cell chemotaxis (GO:0035767) | 2.54197505 |
66 | macromolecular complex disassembly (GO:0032984) | 2.53490178 |
67 | T cell apoptotic process (GO:0070231) | 2.52407474 |
68 | apoptotic process involved in morphogenesis (GO:0060561) | 2.52181784 |
69 | endosome to melanosome transport (GO:0035646) | 2.49559026 |
70 | endosome to pigment granule transport (GO:0043485) | 2.49559026 |
71 | urea cycle (GO:0000050) | 2.49216510 |
72 | amino sugar catabolic process (GO:0046348) | 2.48654377 |
73 | adherens junction assembly (GO:0034333) | 2.48208458 |
74 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241) | 2.48177748 |
75 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 2.47961978 |
76 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.46227186 |
77 | modulation by virus of host process (GO:0019054) | 2.46036736 |
78 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.45520412 |
79 | mitotic chromosome condensation (GO:0007076) | 2.45312721 |
80 | amyloid precursor protein metabolic process (GO:0042982) | 2.43662603 |
81 | modulation by symbiont of host cellular process (GO:0044068) | 2.41632321 |
82 | NADPH regeneration (GO:0006740) | 2.40790671 |
83 | adhesion of symbiont to host (GO:0044406) | 2.40618701 |
84 | snRNA metabolic process (GO:0016073) | 2.40435355 |
85 | positive regulation of nuclease activity (GO:0032075) | 2.40418146 |
86 | hyaluronan catabolic process (GO:0030214) | 2.39498969 |
87 | membrane protein ectodomain proteolysis (GO:0006509) | 2.38974316 |
88 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 2.38627887 |
89 | DNA strand elongation involved in DNA replication (GO:0006271) | 2.37420855 |
90 | proline biosynthetic process (GO:0006561) | 2.37223932 |
91 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 2.36457334 |
92 | establishment of apical/basal cell polarity (GO:0035089) | 2.36208852 |
93 | histone arginine methylation (GO:0034969) | 2.33949942 |
94 | regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315) | 2.33485543 |
95 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 2.32936769 |
96 | membrane protein intracellular domain proteolysis (GO:0031293) | 2.32203057 |
97 | peptidyl-arginine methylation (GO:0018216) | 2.31827114 |
98 | peptidyl-arginine N-methylation (GO:0035246) | 2.31827114 |
99 | DNA unwinding involved in DNA replication (GO:0006268) | 2.31569446 |
100 | positive regulation of DNA-dependent DNA replication (GO:2000105) | 2.30694698 |
101 | NIK/NF-kappaB signaling (GO:0038061) | 2.30690018 |
102 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 2.30627341 |
103 | telomere maintenance via semi-conservative replication (GO:0032201) | 2.29572807 |
104 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.28907329 |
105 | basement membrane organization (GO:0071711) | 2.28515887 |
106 | regulation of superoxide anion generation (GO:0032928) | 2.27280846 |
107 | negative regulation of macroautophagy (GO:0016242) | 2.26863720 |
108 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 2.26226837 |
109 | regulation of cholesterol storage (GO:0010885) | 2.25992419 |
110 | pteridine-containing compound biosynthetic process (GO:0042559) | 2.25839360 |
111 | nucleoside salvage (GO:0043174) | 2.25799945 |
112 | pigment biosynthetic process (GO:0046148) | 2.24680173 |
113 | protein targeting to membrane (GO:0006612) | 2.24417774 |
114 | activation of Rac GTPase activity (GO:0032863) | 2.23924079 |
115 | negative regulation of viral release from host cell (GO:1902187) | 2.23914120 |
116 | mitotic G1 DNA damage checkpoint (GO:0031571) | 2.23575250 |
117 | DNA strand elongation (GO:0022616) | 2.23508436 |
118 | endothelial tube morphogenesis (GO:0061154) | 2.23054941 |
119 | morphogenesis of an endothelium (GO:0003159) | 2.23054941 |
120 | cell-substrate adherens junction assembly (GO:0007045) | 2.22603582 |
121 | focal adhesion assembly (GO:0048041) | 2.22603582 |
122 | sulfur amino acid catabolic process (GO:0000098) | 2.22303784 |
123 | folic acid metabolic process (GO:0046655) | 2.20901146 |
124 | regulation of hippo signaling (GO:0035330) | 2.20154407 |
125 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.19954033 |
126 | endoplasmic reticulum unfolded protein response (GO:0030968) | 2.19433921 |
127 | regulation of apoptotic process involved in morphogenesis (GO:1902337) | 2.18924480 |
128 | endoplasmic reticulum calcium ion homeostasis (GO:0032469) | 2.18299144 |
129 | lymphocyte apoptotic process (GO:0070227) | 2.17233625 |
130 | mRNA catabolic process (GO:0006402) | 2.16660578 |
131 | translation (GO:0006412) | 2.16469779 |
132 | mammary gland epithelial cell differentiation (GO:0060644) | 2.16116025 |
133 | virion assembly (GO:0019068) | 2.15896763 |
134 | cytidine metabolic process (GO:0046087) | 2.15353028 |
135 | cytidine catabolic process (GO:0006216) | 2.15353028 |
136 | cytidine deamination (GO:0009972) | 2.15353028 |
137 | 4-hydroxyproline metabolic process (GO:0019471) | 2.15238070 |
138 | pyrimidine nucleoside salvage (GO:0043097) | 2.13260027 |
139 | pyrimidine-containing compound salvage (GO:0008655) | 2.13260027 |
140 | RNA catabolic process (GO:0006401) | 2.13037712 |
141 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.12961689 |
142 | glucose catabolic process (GO:0006007) | 2.12389847 |
143 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 2.11892729 |
144 | oxidative phosphorylation (GO:0006119) | 2.11113042 |
145 | heme biosynthetic process (GO:0006783) | 2.09886385 |
146 | regulation of SMAD protein import into nucleus (GO:0060390) | 2.05609373 |
147 | regulation of posttranscriptional gene silencing (GO:0060147) | 2.05215791 |
148 | regulation of gene silencing by miRNA (GO:0060964) | 2.05215791 |
149 | regulation of gene silencing by RNA (GO:0060966) | 2.05215791 |
150 | gap junction assembly (GO:0016264) | 2.04641199 |
151 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.03822429 |
152 | mitochondrial DNA metabolic process (GO:0032042) | 2.03210765 |
153 | regulation of translational fidelity (GO:0006450) | 2.02882769 |
154 | regulation of integrin activation (GO:0033623) | 2.01703839 |
155 | negative regulation of innate immune response (GO:0045824) | 2.01687573 |
156 | trophectodermal cell differentiation (GO:0001829) | 2.01046324 |
157 | glycine metabolic process (GO:0006544) | 2.00969190 |
158 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.00920172 |
159 | polarized epithelial cell differentiation (GO:0030859) | 2.00891669 |
160 | negative regulation of cell size (GO:0045792) | 1.99237271 |
161 | response to laminar fluid shear stress (GO:0034616) | 1.98198463 |
162 | nucleotide salvage (GO:0043173) | 1.97933534 |
163 | sarcomere organization (GO:0045214) | 1.97685488 |
164 | atrioventricular valve morphogenesis (GO:0003181) | 1.97252976 |
165 | endodermal cell differentiation (GO:0035987) | 1.96964584 |
166 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 1.96284885 |
167 | regulation of gamma-delta T cell differentiation (GO:0045586) | 1.95620351 |
168 | mitotic G1/S transition checkpoint (GO:0044819) | 1.94627024 |
169 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 1.94264670 |
170 | cellular hyperosmotic response (GO:0071474) | 1.93656168 |
171 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 1.93226012 |
172 | hemidesmosome assembly (GO:0031581) | 1.93037300 |
173 | regulation of cholesterol homeostasis (GO:2000188) | 1.91602144 |
174 | paraxial mesoderm development (GO:0048339) | 1.91462584 |
175 | regulation of protein heterodimerization activity (GO:0043497) | 1.90359555 |
176 | proline metabolic process (GO:0006560) | 1.90162242 |
177 | telomere maintenance via recombination (GO:0000722) | 1.90012291 |
178 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO | 1.88973096 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.56496011 |
2 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 3.55174114 |
3 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.11335314 |
4 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.50862285 |
5 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.41088459 |
6 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.20607911 |
7 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.13184997 |
8 | MYC_22102868_ChIP-Seq_BL_Human | 2.09603235 |
9 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.96073720 |
10 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.88660617 |
11 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.87663600 |
12 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.86187542 |
13 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.83341834 |
14 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.77916947 |
15 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.75451649 |
16 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.71124709 |
17 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.67137728 |
18 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.64920163 |
19 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.64356507 |
20 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.64248982 |
21 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.63893463 |
22 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.63114056 |
23 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.62754850 |
24 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.60441768 |
25 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.54658562 |
26 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.50492036 |
27 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.47714545 |
28 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.46165742 |
29 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.45572040 |
30 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.44149917 |
31 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.43717071 |
32 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.43331215 |
33 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.41758409 |
34 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.40873025 |
35 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.40689733 |
36 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.38835127 |
37 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.37093487 |
38 | ATF3_27146783_Chip-Seq_COLON_Human | 1.36487367 |
39 | * ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.36485869 |
40 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.35348282 |
41 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.34511484 |
42 | MAF_26560356_Chip-Seq_TH1_Human | 1.33071094 |
43 | * NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.33024534 |
44 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.32802895 |
45 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.32223866 |
46 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.30818961 |
47 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.30098546 |
48 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.28528695 |
49 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.28460590 |
50 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.26841021 |
51 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.26432706 |
52 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.26080942 |
53 | * CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.25560794 |
54 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.24670471 |
55 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.24445562 |
56 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.22993996 |
57 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.22720191 |
58 | UTX_26944678_Chip-Seq_JUKART_Human | 1.22565576 |
59 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.21780445 |
60 | KDM2B_26808549_Chip-Seq_K562_Human | 1.21142741 |
61 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.20761645 |
62 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.20568398 |
63 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.20314946 |
64 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.18315195 |
65 | * CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.18030441 |
66 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.17975990 |
67 | * GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.16946416 |
68 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.16727711 |
69 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.16588649 |
70 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.16395197 |
71 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.16381959 |
72 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.16244639 |
73 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.14729602 |
74 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.14679318 |
75 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.14525417 |
76 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.14260075 |
77 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.14027788 |
78 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.13633876 |
79 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.13545017 |
80 | * CTCF_26484167_Chip-Seq_Bcells_Mouse | 1.12789813 |
81 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.11921066 |
82 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.11680668 |
83 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.11651690 |
84 | * HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.10638668 |
85 | * RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.09891093 |
86 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.09789433 |
87 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.08796607 |
88 | * PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.08499593 |
89 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.07630595 |
90 | MAF_26560356_Chip-Seq_TH2_Human | 1.07547650 |
91 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.07474177 |
92 | * NCOR1_26117541_ChIP-Seq_K562_Human | 1.07222854 |
93 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.07104885 |
94 | * BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.06949075 |
95 | * CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.06811227 |
96 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.06426397 |
97 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.06138964 |
98 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.05938638 |
99 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.05757266 |
100 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.05345741 |
101 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.04953612 |
102 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.04779836 |
103 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.04657885 |
104 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.04513142 |
105 | * CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.04035027 |
106 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.03568661 |
107 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.03208590 |
108 | * P68_20966046_ChIP-Seq_HELA_Human | 1.02549794 |
109 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.02315541 |
110 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.01831649 |
111 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.00098117 |
112 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.99563395 |
113 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.99097938 |
114 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.98825465 |
115 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.98234303 |
116 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 0.97846709 |
117 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.97565635 |
118 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 0.97411173 |
119 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 0.96358856 |
120 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 0.96329609 |
121 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.96171557 |
122 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.96031323 |
123 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.95924790 |
124 | * RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.95410800 |
125 | CTCF_21964334_Chip-Seq_Bcells_Human | 0.95306716 |
126 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.94338218 |
127 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.94273702 |
128 | * SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.94269087 |
129 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.93358946 |
130 | SCL_19346495_ChIP-Seq_HPC-7_Human | 0.92991894 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005171_absent_coat_pigmentation | 4.48935963 |
2 | MP0003136_yellow_coat_color | 3.69756246 |
3 | MP0000015_abnormal_ear_pigmentation | 3.20868060 |
4 | MP0004381_abnormal_hair_follicle | 3.06485578 |
5 | MP0003705_abnormal_hypodermis_morpholog | 3.00212809 |
6 | MP0000372_irregular_coat_pigmentation | 2.95029460 |
7 | MP0005075_abnormal_melanosome_morpholog | 2.67960578 |
8 | MP0005257_abnormal_intraocular_pressure | 2.58530532 |
9 | MP0005408_hypopigmentation | 2.38326719 |
10 | MP0005409_darkened_coat_color | 2.36798143 |
11 | MP0003172_abnormal_lysosome_physiology | 2.20999726 |
12 | MP0008260_abnormal_autophagy | 2.17284679 |
13 | MP0000371_diluted_coat_color | 2.11581097 |
14 | MP0003566_abnormal_cell_adhesion | 2.02034836 |
15 | MP0009840_abnormal_foam_cell | 1.94331889 |
16 | MP0010352_gastrointestinal_tract_polyps | 1.90591601 |
17 | MP0005174_abnormal_tail_pigmentation | 1.90373773 |
18 | MP0010030_abnormal_orbit_morphology | 1.88957463 |
19 | MP0004858_abnormal_nervous_system | 1.85495424 |
20 | MP0008438_abnormal_cutaneous_collagen | 1.73740724 |
21 | MP0002075_abnormal_coat/hair_pigmentati | 1.69229082 |
22 | MP0009278_abnormal_bone_marrow | 1.63266003 |
23 | MP0000678_abnormal_parathyroid_gland | 1.62559012 |
24 | MP0003693_abnormal_embryo_hatching | 1.54153298 |
25 | MP0000490_abnormal_crypts_of | 1.53779311 |
26 | MP0002095_abnormal_skin_pigmentation | 1.49420156 |
27 | MP0003806_abnormal_nucleotide_metabolis | 1.45114912 |
28 | MP0005360_urolithiasis | 1.44829069 |
29 | MP0005464_abnormal_platelet_physiology | 1.44473180 |
30 | MP0005023_abnormal_wound_healing | 1.42868723 |
31 | MP0005275_abnormal_skin_tensile | 1.41028400 |
32 | MP0004957_abnormal_blastocyst_morpholog | 1.39769661 |
33 | MP0003191_abnormal_cellular_cholesterol | 1.39342727 |
34 | MP0001186_pigmentation_phenotype | 1.37716627 |
35 | MP0003283_abnormal_digestive_organ | 1.33294611 |
36 | MP0002396_abnormal_hematopoietic_system | 1.31903395 |
37 | MP0000685_abnormal_immune_system | 1.31303000 |
38 | MP0004084_abnormal_cardiac_muscle | 1.30737290 |
39 | MP0003279_aneurysm | 1.30610646 |
40 | MP0003300_gastrointestinal_ulcer | 1.25329563 |
41 | MP0005076_abnormal_cell_differentiation | 1.24760515 |
42 | MP0002060_abnormal_skin_morphology | 1.24726208 |
43 | MP0003567_abnormal_fetal_cardiomyocyte | 1.24264427 |
44 | MP0006054_spinal_hemorrhage | 1.24023204 |
45 | MP0010155_abnormal_intestine_physiology | 1.24000864 |
46 | MP0003453_abnormal_keratinocyte_physiol | 1.22791337 |
47 | MP0009333_abnormal_splenocyte_physiolog | 1.22558266 |
48 | MP0003111_abnormal_nucleus_morphology | 1.21265972 |
49 | MP0001545_abnormal_hematopoietic_system | 1.21119250 |
50 | MP0005397_hematopoietic_system_phenotyp | 1.21119250 |
51 | MP0002089_abnormal_postnatal_growth/wei | 1.20167523 |
52 | MP0001849_ear_inflammation | 1.19529336 |
53 | MP0010234_abnormal_vibrissa_follicle | 1.19272676 |
54 | MP0004233_abnormal_muscle_weight | 1.18838168 |
55 | MP0003077_abnormal_cell_cycle | 1.14055868 |
56 | MP0005377_hearing/vestibular/ear_phenot | 1.13115012 |
57 | MP0003878_abnormal_ear_physiology | 1.13115012 |
58 | MP0009053_abnormal_anal_canal | 1.12853952 |
59 | MP0004272_abnormal_basement_membrane | 1.12262635 |
60 | MP0005670_abnormal_white_adipose | 1.09827163 |
61 | MP0010630_abnormal_cardiac_muscle | 1.09488751 |
62 | MP0010368_abnormal_lymphatic_system | 1.08149485 |
63 | MP0003303_peritoneal_inflammation | 1.07361707 |
64 | MP0002138_abnormal_hepatobiliary_system | 1.07272644 |
65 | MP0005501_abnormal_skin_physiology | 1.07210463 |
66 | MP0000003_abnormal_adipose_tissue | 1.07155126 |
67 | MP0002796_impaired_skin_barrier | 1.07048727 |
68 | MP0005058_abnormal_lysosome_morphology | 1.06648120 |
69 | MP0003828_pulmonary_edema | 1.05571974 |
70 | MP0000477_abnormal_intestine_morphology | 1.05268332 |
71 | MP0002249_abnormal_larynx_morphology | 1.05151694 |
72 | MP0000750_abnormal_muscle_regeneration | 1.04849274 |
73 | MP0000733_abnormal_muscle_development | 1.03048006 |
74 | MP0002877_abnormal_melanocyte_morpholog | 1.02272297 |
75 | MP0008007_abnormal_cellular_replicative | 1.00986729 |
76 | MP0005330_cardiomyopathy | 1.00055792 |
77 | MP0000767_abnormal_smooth_muscle | 0.99718298 |
78 | MP0003436_decreased_susceptibility_to | 0.99201077 |
79 | MP0004808_abnormal_hematopoietic_stem | 0.97348351 |
80 | MP0005375_adipose_tissue_phenotype | 0.96608791 |
81 | MP0004947_skin_inflammation | 0.96586750 |
82 | MP0001873_stomach_inflammation | 0.96445720 |
83 | MP0004185_abnormal_adipocyte_glucose | 0.93011636 |
84 | MP0009643_abnormal_urine_homeostasis | 0.92077134 |
85 | MP0002166_altered_tumor_susceptibility | 0.91867169 |
86 | MP0003252_abnormal_bile_duct | 0.91693345 |
87 | MP0002254_reproductive_system_inflammat | 0.91537492 |
88 | MP0002234_abnormal_pharynx_morphology | 0.90407761 |
89 | MP0008932_abnormal_embryonic_tissue | 0.90369664 |
90 | MP0001730_embryonic_growth_arrest | 0.90223411 |
91 | MP0000350_abnormal_cell_proliferation | 0.89434138 |
92 | MP0005083_abnormal_biliary_tract | 0.88892673 |
93 | MP0005666_abnormal_adipose_tissue | 0.86517125 |
94 | MP0002086_abnormal_extraembryonic_tissu | 0.86004223 |
95 | MP0003984_embryonic_growth_retardation | 0.85573077 |
96 | MP0002088_abnormal_embryonic_growth/wei | 0.84796927 |
97 | MP0000467_abnormal_esophagus_morphology | 0.84325436 |
98 | MP0001243_abnormal_dermal_layer | 0.83958426 |
99 | MP0000858_altered_metastatic_potential | 0.83164454 |
100 | MP0000681_abnormal_thyroid_gland | 0.82564549 |
101 | MP0005380_embryogenesis_phenotype | 0.82487428 |
102 | MP0001672_abnormal_embryogenesis/_devel | 0.82487428 |
103 | MP0003186_abnormal_redox_activity | 0.82476116 |
104 | MP0002019_abnormal_tumor_incidence | 0.82266342 |
105 | MP0000598_abnormal_liver_morphology | 0.81509860 |
106 | MP0004264_abnormal_extraembryonic_tissu | 0.80619122 |
107 | MP0003941_abnormal_skin_development | 0.79587078 |
108 | MP0010094_abnormal_chromosome_stability | 0.79185750 |
109 | MP0002139_abnormal_hepatobiliary_system | 0.78698178 |
110 | MP0005319_abnormal_enzyme/_coenzyme | 0.76676569 |
111 | MP0000343_altered_response_to | 0.76447939 |
112 | MP0004087_abnormal_muscle_fiber | 0.76236999 |
113 | MP0001853_heart_inflammation | 0.76218341 |
114 | MP0002148_abnormal_hypersensitivity_rea | 0.75433585 |
115 | MP0005451_abnormal_body_composition | 0.75294530 |
116 | MP0002080_prenatal_lethality | 0.75172280 |
117 | MP0002998_abnormal_bone_remodeling | 0.75070283 |
118 | MP0001958_emphysema | 0.75024700 |
119 | MP0002098_abnormal_vibrissa_morphology | 0.74733263 |
120 | MP0001697_abnormal_embryo_size | 0.74565422 |
121 | MP0000609_abnormal_liver_physiology | 0.74480880 |
122 | MP0003763_abnormal_thymus_physiology | 0.74238034 |
123 | MP0001544_abnormal_cardiovascular_syste | 0.73627779 |
124 | MP0005385_cardiovascular_system_phenoty | 0.73627779 |
125 | MP0002722_abnormal_immune_system | 0.73530694 |
126 | MP0009931_abnormal_skin_appearance | 0.73443007 |
127 | MP0000377_abnormal_hair_follicle | 0.73146942 |
128 | MP0002419_abnormal_innate_immunity | 0.72113405 |
129 | MP0001216_abnormal_epidermal_layer | 0.71595586 |
130 | MP0001835_abnormal_antigen_presentation | 0.71561907 |
131 | MP0000358_abnormal_cell_content/ | 0.71542313 |
132 | MP0004197_abnormal_fetal_growth/weight/ | 0.70820576 |
133 | MP0001348_abnormal_lacrimal_gland | 0.70707010 |
134 | MP0005025_abnormal_response_to | 0.70680066 |
135 | MP0006138_congestive_heart_failure | 0.70569649 |
136 | MP0002398_abnormal_bone_marrow | 0.69799263 |
137 | MP0001881_abnormal_mammary_gland | 0.68285588 |
138 | MP0000367_abnormal_coat/_hair | 0.66917562 |
139 | MP0000465_gastrointestinal_hemorrhage | 0.66105212 |
140 | MP0005621_abnormal_cell_physiology | 0.64523194 |
141 | MP0003091_abnormal_cell_migration | 0.63394797 |
142 | MP0001188_hyperpigmentation | 0.62105607 |
143 | MP0005623_abnormal_meninges_morphology | 0.60857269 |
144 | MP0000537_abnormal_urethra_morphology | 0.60819519 |
145 | MP0001533_abnormal_skeleton_physiology | 0.59028292 |
146 | MP0000313_abnormal_cell_death | 0.57582048 |
147 | MP0001324_abnormal_eye_pigmentation | 0.55728354 |
148 | MP0004510_myositis | 0.55416155 |
149 | MP0009384_cardiac_valve_regurgitation | 0.55403208 |
150 | MP0003183_abnormal_peptide_metabolism | 0.55230853 |
Rank | Gene Set | Z-score |
---|---|---|
1 | White forelock (HP:0002211) | 4.29435227 |
2 | Abnormality of glycolipid metabolism (HP:0010969) | 3.96227910 |
3 | Abnormality of liposaccharide metabolism (HP:0010968) | 3.96227910 |
4 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 3.96227910 |
5 | Protrusio acetabuli (HP:0003179) | 3.64049063 |
6 | Patchy hypopigmentation of hair (HP:0011365) | 3.62972874 |
7 | Pustule (HP:0200039) | 3.50861166 |
8 | Ocular albinism (HP:0001107) | 3.50748035 |
9 | J-shaped sella turcica (HP:0002680) | 3.50062250 |
10 | Increased cerebral lipofuscin (HP:0011813) | 3.24528323 |
11 | Dysostosis multiplex (HP:0000943) | 3.06468200 |
12 | Reticulocytopenia (HP:0001896) | 3.02137072 |
13 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.94875868 |
14 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.89070449 |
15 | Aplasia/Hypoplasia of the macula (HP:0008059) | 2.87411864 |
16 | Right ventricular cardiomyopathy (HP:0011663) | 2.81902319 |
17 | Ankle contracture (HP:0006466) | 2.81483723 |
18 | Premature rupture of membranes (HP:0001788) | 2.75500428 |
19 | Ventricular tachycardia (HP:0004756) | 2.74393874 |
20 | Abnormal number of erythroid precursors (HP:0012131) | 2.72321644 |
21 | Achilles tendon contracture (HP:0001771) | 2.68516589 |
22 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 2.66523787 |
23 | Abnormal gallbladder physiology (HP:0012438) | 2.65964306 |
24 | Cholecystitis (HP:0001082) | 2.65964306 |
25 | Iris hypopigmentation (HP:0007730) | 2.65073559 |
26 | Broad face (HP:0000283) | 2.52298233 |
27 | Distal lower limb amyotrophy (HP:0008944) | 2.48464475 |
28 | Loss of speech (HP:0002371) | 2.46398734 |
29 | Heterochromia iridis (HP:0001100) | 2.44748098 |
30 | Increased connective tissue (HP:0009025) | 2.44215992 |
31 | Cerebral aneurysm (HP:0004944) | 2.42955490 |
32 | Trismus (HP:0000211) | 2.41586788 |
33 | Hypoplasia of the fovea (HP:0007750) | 2.40744017 |
34 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.40744017 |
35 | Hypopigmentation of the fundus (HP:0007894) | 2.39742016 |
36 | Multiple enchondromatosis (HP:0005701) | 2.38355721 |
37 | Abnormality of the Achilles tendon (HP:0005109) | 2.35392035 |
38 | Nuclear cataract (HP:0100018) | 2.34941487 |
39 | Flat acetabular roof (HP:0003180) | 2.34720308 |
40 | Fragile skin (HP:0001030) | 2.34154535 |
41 | Stridor (HP:0010307) | 2.33586085 |
42 | Alopecia of scalp (HP:0002293) | 2.30405470 |
43 | Polycythemia (HP:0001901) | 2.28565862 |
44 | Distal upper limb amyotrophy (HP:0007149) | 2.27724944 |
45 | Upper limb amyotrophy (HP:0009129) | 2.27724944 |
46 | Cervical subluxation (HP:0003308) | 2.26759790 |
47 | Purpura (HP:0000979) | 2.25079326 |
48 | Elbow flexion contracture (HP:0002987) | 2.24353325 |
49 | Hypertensive crisis (HP:0100735) | 2.22367734 |
50 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.21651265 |
51 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.21651265 |
52 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.21651265 |
53 | Mesangial abnormality (HP:0001966) | 2.19499339 |
54 | Bulbar palsy (HP:0001283) | 2.18745238 |
55 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.17755021 |
56 | Mucopolysacchariduria (HP:0008155) | 2.17755021 |
57 | Selective tooth agenesis (HP:0001592) | 2.17527425 |
58 | Peritonitis (HP:0002586) | 2.13434214 |
59 | Hepatosplenomegaly (HP:0001433) | 2.11859778 |
60 | Abnormal cartilage morphology (HP:0002763) | 2.11841389 |
61 | Biconcave vertebral bodies (HP:0004586) | 2.11266838 |
62 | Broad metatarsal (HP:0001783) | 2.07756223 |
63 | Atrophic scars (HP:0001075) | 2.07366964 |
64 | Abnormality of the thoracic spine (HP:0100711) | 2.06912465 |
65 | Microretrognathia (HP:0000308) | 2.06368998 |
66 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.05014143 |
67 | Deformed sella turcica (HP:0002681) | 2.02770109 |
68 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.02495110 |
69 | Esophageal neoplasm (HP:0100751) | 2.02404769 |
70 | Neoplasm of head and neck (HP:0012288) | 2.02404769 |
71 | Macrocytic anemia (HP:0001972) | 2.02284842 |
72 | Vacuolated lymphocytes (HP:0001922) | 2.02173652 |
73 | Long palpebral fissure (HP:0000637) | 1.98401933 |
74 | Pallor (HP:0000980) | 1.96893156 |
75 | Natal tooth (HP:0000695) | 1.94715860 |
76 | Long toe (HP:0010511) | 1.93255477 |
77 | Prolonged neonatal jaundice (HP:0006579) | 1.92140761 |
78 | Dicarboxylic aciduria (HP:0003215) | 1.92010293 |
79 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.92010293 |
80 | Blue sclerae (HP:0000592) | 1.91882326 |
81 | Hypoglycemic coma (HP:0001325) | 1.91491067 |
82 | Thrombocytosis (HP:0001894) | 1.91299172 |
83 | Hemorrhage of the eye (HP:0011885) | 1.89863100 |
84 | Nausea (HP:0002018) | 1.89831048 |
85 | Generalized amyotrophy (HP:0003700) | 1.89684569 |
86 | Premature graying of hair (HP:0002216) | 1.89639498 |
87 | Sparse lateral eyebrow (HP:0005338) | 1.89383876 |
88 | Reticulocytosis (HP:0001923) | 1.89284728 |
89 | Ulnar bowing (HP:0003031) | 1.88706744 |
90 | Abnormality of reticulocytes (HP:0004312) | 1.88688904 |
91 | Short nail (HP:0001799) | 1.88044567 |
92 | Blue irides (HP:0000635) | 1.87882152 |
93 | Thoracic kyphosis (HP:0002942) | 1.85990602 |
94 | Breech presentation (HP:0001623) | 1.85801662 |
95 | Hyperparathyroidism (HP:0000843) | 1.85681973 |
96 | Rectal prolapse (HP:0002035) | 1.85640806 |
97 | Increased serum ferritin (HP:0003281) | 1.85568832 |
98 | Insomnia (HP:0100785) | 1.85472277 |
99 | Petechiae (HP:0000967) | 1.85334830 |
100 | Cutaneous melanoma (HP:0012056) | 1.84856842 |
101 | Hypoplasia of the iris (HP:0007676) | 1.84002497 |
102 | Abnormal hemoglobin (HP:0011902) | 1.83859084 |
103 | Abnormality of the acetabulum (HP:0003170) | 1.81876887 |
104 | Abnormality of the umbilical cord (HP:0010881) | 1.81326016 |
105 | Spastic paraparesis (HP:0002313) | 1.81212263 |
106 | Axonal loss (HP:0003447) | 1.80756590 |
107 | Broad distal phalanx of finger (HP:0009836) | 1.80657148 |
108 | Nonimmune hydrops fetalis (HP:0001790) | 1.80377694 |
109 | Lipoatrophy (HP:0100578) | 1.79286021 |
110 | Hand muscle atrophy (HP:0009130) | 1.79092880 |
111 | Vertebral compression fractures (HP:0002953) | 1.78751455 |
112 | Testicular atrophy (HP:0000029) | 1.78655521 |
113 | Atelectasis (HP:0100750) | 1.78610414 |
114 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.77696633 |
115 | Genu recurvatum (HP:0002816) | 1.76133949 |
116 | Asymmetric septal hypertrophy (HP:0001670) | 1.75899138 |
117 | Esophageal varix (HP:0002040) | 1.75293067 |
118 | Patellar dislocation (HP:0002999) | 1.73635046 |
119 | Neonatal short-limb short stature (HP:0008921) | 1.72294603 |
120 | Cellulitis (HP:0100658) | 1.70789013 |
121 | Shallow orbits (HP:0000586) | 1.69884138 |
122 | Gastrointestinal inflammation (HP:0004386) | 1.69524357 |
123 | Abdominal distention (HP:0003270) | 1.68803602 |
124 | Sudden death (HP:0001699) | 1.68303810 |
125 | Hyperglycinuria (HP:0003108) | 1.67636551 |
126 | Ileus (HP:0002595) | 1.67539856 |
127 | Paraparesis (HP:0002385) | 1.67507744 |
128 | Interstitial pulmonary disease (HP:0006530) | 1.66875170 |
129 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.66576201 |
130 | Abnormality of the fovea (HP:0000493) | 1.66133557 |
131 | Hypertriglyceridemia (HP:0002155) | 1.65385806 |
132 | Myopathic facies (HP:0002058) | 1.65174278 |
133 | Abnormality of the nasal mucosa (HP:0000433) | 1.64361836 |
134 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.64007255 |
135 | Osteolytic defects of the hand bones (HP:0009699) | 1.64007255 |
136 | Cheilitis (HP:0100825) | 1.63836211 |
137 | Distal lower limb muscle weakness (HP:0009053) | 1.63387917 |
138 | Pili torti (HP:0003777) | 1.62791735 |
139 | Rhabdomyolysis (HP:0003201) | 1.61429538 |
140 | Neonatal death (HP:0003811) | 1.59437581 |
141 | Difficulty climbing stairs (HP:0003551) | 1.59352674 |
142 | Progressive muscle weakness (HP:0003323) | 1.59308283 |
143 | Aortic dissection (HP:0002647) | 1.56383096 |
144 | Inflammation of the large intestine (HP:0002037) | 1.56348149 |
145 | Late onset (HP:0003584) | 1.55010346 |
146 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.54968719 |
147 | Colitis (HP:0002583) | 1.53895078 |
148 | Abnormality of T cell physiology (HP:0011840) | 1.53552104 |
149 | Woolly hair (HP:0002224) | 1.51992288 |
150 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.51492008 |
151 | Hyperacusis (HP:0010780) | 1.50910498 |
152 | Thin bony cortex (HP:0002753) | 1.50579701 |
153 | Bladder diverticulum (HP:0000015) | 1.50072441 |
154 | Abnormality of fatty-acid metabolism (HP:0004359) | 1.49305941 |
155 | Bowing of the arm (HP:0006488) | 1.49271998 |
156 | Bowed forearm bones (HP:0003956) | 1.49271998 |
157 | Impaired platelet aggregation (HP:0003540) | 1.49032308 |
158 | Abnormal platelet function (HP:0011869) | 1.49032308 |
159 | Vertebral clefting (HP:0008428) | 1.48989857 |
160 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.48693291 |
161 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.48693291 |
162 | Dilated cardiomyopathy (HP:0001644) | 1.48361954 |
163 | Myoglobinuria (HP:0002913) | 1.47892958 |
164 | Ragged-red muscle fibers (HP:0003200) | 1.47856528 |
165 | Type 1 muscle fiber predominance (HP:0003803) | 1.47803166 |
166 | Muscle fiber splitting (HP:0003555) | 1.46960105 |
167 | Vertebral hypoplasia (HP:0008417) | 1.46276452 |
168 | Aplasia/Hypoplasia of the vertebrae (HP:0008515) | 1.46276452 |
169 | Mitral valve prolapse (HP:0001634) | 1.46260761 |
170 | Breast hypoplasia (HP:0003187) | 1.45185382 |
171 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 1.45127977 |
172 | Joint stiffness (HP:0001387) | 1.44792121 |
173 | Aortic aneurysm (HP:0004942) | 1.44621956 |
174 | Xanthomatosis (HP:0000991) | 1.44245649 |
175 | Abnormality of the peritoneum (HP:0002585) | 1.42962070 |
176 | Soft skin (HP:0000977) | 1.42454840 |
177 | Milia (HP:0001056) | 1.41829501 |
178 | Myocardial infarction (HP:0001658) | 1.41803448 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIB3 | 3.58039115 |
2 | SMG1 | 3.46014614 |
3 | ERN1 | 3.04947816 |
4 | PKN2 | 2.92148645 |
5 | MAP3K10 | 2.62502308 |
6 | NME2 | 2.37068314 |
7 | EEF2K | 2.10954607 |
8 | TIE1 | 2.00896964 |
9 | PRPF4B | 2.00853640 |
10 | BCKDK | 1.97119873 |
11 | TTN | 1.84860198 |
12 | VRK2 | 1.80561972 |
13 | KDR | 1.76174466 |
14 | MAP4K1 | 1.75964206 |
15 | FLT3 | 1.71067257 |
16 | TAOK3 | 1.61613144 |
17 | LRRK2 | 1.59186814 |
18 | NEK2 | 1.58808654 |
19 | PAK4 | 1.58266296 |
20 | MAPKAPK3 | 1.56819840 |
21 | EPHB2 | 1.56800205 |
22 | RPS6KB2 | 1.53125631 |
23 | STK10 | 1.48831221 |
24 | RPS6KA4 | 1.48665903 |
25 | TGFBR2 | 1.44702122 |
26 | EPHA2 | 1.43746588 |
27 | MAP2K2 | 1.43468801 |
28 | MAP3K11 | 1.42110781 |
29 | TESK2 | 1.39902470 |
30 | PIM2 | 1.37146832 |
31 | TLK1 | 1.35921938 |
32 | BUB1 | 1.35369632 |
33 | PIK3CA | 1.30858710 |
34 | NEK1 | 1.30561022 |
35 | SIK1 | 1.28116328 |
36 | RIPK1 | 1.24764702 |
37 | ILK | 1.22682044 |
38 | ARAF | 1.19859437 |
39 | PRKD3 | 1.19854703 |
40 | MAP2K3 | 1.18419598 |
41 | PTK6 | 1.17016288 |
42 | TBK1 | 1.14704175 |
43 | FGFR4 | 1.13947255 |
44 | ICK | 1.13255601 |
45 | RPS6KA2 | 1.12070747 |
46 | WEE1 | 1.11182477 |
47 | MAP3K8 | 1.08454306 |
48 | TYK2 | 1.07838025 |
49 | CDK7 | 1.02724607 |
50 | DYRK1B | 0.99978292 |
51 | PDGFRA | 0.98886842 |
52 | BMX | 0.98123531 |
53 | CDK12 | 0.96175127 |
54 | DYRK3 | 0.95991114 |
55 | PASK | 0.93317240 |
56 | CDK4 | 0.93002010 |
57 | TAOK1 | 0.92909167 |
58 | PDK2 | 0.92384077 |
59 | PIM1 | 0.90238296 |
60 | KIT | 0.89334489 |
61 | TGFBR1 | 0.88586004 |
62 | LIMK1 | 0.84228397 |
63 | MAPK11 | 0.83998308 |
64 | MATK | 0.83836458 |
65 | DDR2 | 0.83702933 |
66 | ABL2 | 0.83559763 |
67 | MAP3K1 | 0.83017069 |
68 | PDPK1 | 0.82347013 |
69 | AURKB | 0.82172396 |
70 | MTOR | 0.80067473 |
71 | MAP3K3 | 0.79102336 |
72 | TESK1 | 0.78326414 |
73 | ZAP70 | 0.76865129 |
74 | IKBKB | 0.75450675 |
75 | DMPK | 0.75425370 |
76 | GRK6 | 0.74782340 |
77 | JAK3 | 0.74687980 |
78 | CDC42BPA | 0.74595048 |
79 | TTK | 0.72385617 |
80 | LMTK2 | 0.72308491 |
81 | CHUK | 0.68424292 |
82 | MARK3 | 0.68070604 |
83 | MAP3K6 | 0.67433359 |
84 | BTK | 0.67125644 |
85 | SIK3 | 0.66257572 |
86 | BRAF | 0.66009436 |
87 | STK4 | 0.64774504 |
88 | HIPK2 | 0.64061519 |
89 | AURKA | 0.62419179 |
90 | CDK6 | 0.62345943 |
91 | SCYL2 | 0.62117941 |
92 | MAP3K7 | 0.61309975 |
93 | PRKG2 | 0.61074880 |
94 | STK38L | 0.61029911 |
95 | BLK | 0.61028363 |
96 | IRAK3 | 0.58795745 |
97 | PAK2 | 0.58740650 |
98 | CSK | 0.58247924 |
99 | MYLK | 0.58033168 |
100 | PLK1 | 0.57704334 |
101 | MAP3K13 | 0.57604375 |
102 | TEC | 0.56708070 |
103 | DAPK3 | 0.56597294 |
104 | DAPK1 | 0.56189844 |
105 | PTK2 | 0.55785843 |
106 | CSF1R | 0.55124676 |
107 | MAPK15 | 0.52400075 |
108 | NEK9 | 0.52064664 |
109 | TRPM7 | 0.51833090 |
110 | PAK1 | 0.51449226 |
111 | MST1R | 0.50187785 |
112 | TAOK2 | 0.50058163 |
113 | PRKCI | 0.49802428 |
114 | MAPKAPK2 | 0.49011513 |
115 | IRAK4 | 0.48659695 |
116 | IRAK2 | 0.48370645 |
117 | EPHB1 | 0.47966498 |
118 | EIF2AK1 | 0.47816583 |
119 | RPS6KA6 | 0.47797711 |
120 | RPS6KC1 | 0.46952808 |
121 | RPS6KL1 | 0.46952808 |
122 | PRKD2 | 0.45869719 |
123 | AKT2 | 0.45767807 |
124 | MAP3K14 | 0.45376377 |
125 | CDC7 | 0.41261338 |
126 | PRKD1 | 0.40956254 |
127 | MET | 0.40516013 |
128 | TNK2 | 0.38859030 |
129 | MARK2 | 0.38005602 |
130 | CDK8 | 0.36694372 |
131 | PBK | 0.34541546 |
132 | MOS | 0.33605332 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ribosome_Homo sapiens_hsa03010 | 3.20296148 |
2 | DNA replication_Homo sapiens_hsa03030 | 2.78253783 |
3 | Lysosome_Homo sapiens_hsa04142 | 2.26309424 |
4 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 2.06274534 |
5 | Mismatch repair_Homo sapiens_hsa03430 | 2.01966517 |
6 | Base excision repair_Homo sapiens_hsa03410 | 2.00998392 |
7 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.76439777 |
8 | Sulfur relay system_Homo sapiens_hsa04122 | 1.71175014 |
9 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.55476316 |
10 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.48500036 |
11 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.48294479 |
12 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.45587324 |
13 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.44153164 |
14 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.40586774 |
15 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.40399167 |
16 | Carbon metabolism_Homo sapiens_hsa01200 | 1.40366048 |
17 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.34717901 |
18 | Spliceosome_Homo sapiens_hsa03040 | 1.33829962 |
19 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.31878327 |
20 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.29378429 |
21 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.28384940 |
22 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.27229293 |
23 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.26237446 |
24 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.25902439 |
25 | Bladder cancer_Homo sapiens_hsa05219 | 1.25248275 |
26 | Cell cycle_Homo sapiens_hsa04110 | 1.24747516 |
27 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.21603593 |
28 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.20756865 |
29 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.20689879 |
30 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.17689830 |
31 | Galactose metabolism_Homo sapiens_hsa00052 | 1.15616742 |
32 | Homologous recombination_Homo sapiens_hsa03440 | 1.15352299 |
33 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.14801188 |
34 | Endometrial cancer_Homo sapiens_hsa05213 | 1.11940418 |
35 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.10886939 |
36 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.10146358 |
37 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.09381394 |
38 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.05208194 |
39 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.05085050 |
40 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.02482026 |
41 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.00879955 |
42 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.00841022 |
43 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.00770466 |
44 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.00048270 |
45 | RNA transport_Homo sapiens_hsa03013 | 0.99788577 |
46 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.99671220 |
47 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.97700820 |
48 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.96813246 |
49 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.96207399 |
50 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.94087756 |
51 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.93698297 |
52 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.90629926 |
53 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.89688125 |
54 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.89356172 |
55 | Apoptosis_Homo sapiens_hsa04210 | 0.89272511 |
56 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.89266483 |
57 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.88927385 |
58 | Leishmaniasis_Homo sapiens_hsa05140 | 0.88355988 |
59 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.87445131 |
60 | Hepatitis C_Homo sapiens_hsa05160 | 0.87236782 |
61 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.87067272 |
62 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.87008543 |
63 | Thyroid cancer_Homo sapiens_hsa05216 | 0.86931811 |
64 | Prion diseases_Homo sapiens_hsa05020 | 0.85019657 |
65 | Other glycan degradation_Homo sapiens_hsa00511 | 0.84693441 |
66 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.83720329 |
67 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.82230304 |
68 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.81836905 |
69 | Legionellosis_Homo sapiens_hsa05134 | 0.81297187 |
70 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.81164198 |
71 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.80425932 |
72 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.78826827 |
73 | Lysine degradation_Homo sapiens_hsa00310 | 0.77267575 |
74 | Endocytosis_Homo sapiens_hsa04144 | 0.76977775 |
75 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.76662434 |
76 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.75832499 |
77 | Adherens junction_Homo sapiens_hsa04520 | 0.74957705 |
78 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.74556112 |
79 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.74293526 |
80 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.74045498 |
81 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.73585806 |
82 | HTLV-I infection_Homo sapiens_hsa05166 | 0.73072521 |
83 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.72510339 |
84 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.70916633 |
85 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.70627738 |
86 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.70273195 |
87 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.70265624 |
88 | Shigellosis_Homo sapiens_hsa05131 | 0.69797942 |
89 | Prostate cancer_Homo sapiens_hsa05215 | 0.69274730 |
90 | Proteasome_Homo sapiens_hsa03050 | 0.69233370 |
91 | Salmonella infection_Homo sapiens_hsa05132 | 0.68959143 |
92 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.68731676 |
93 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.67745880 |
94 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.67717107 |
95 | Viral myocarditis_Homo sapiens_hsa05416 | 0.67231843 |
96 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.66792006 |
97 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.66658147 |
98 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.65447786 |
99 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.65421721 |
100 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.64678529 |
101 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.64528675 |
102 | Focal adhesion_Homo sapiens_hsa04510 | 0.64476229 |
103 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.63471510 |
104 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.63302108 |
105 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.62365644 |
106 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.60956066 |
107 | Measles_Homo sapiens_hsa05162 | 0.60625048 |
108 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.59888000 |
109 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.58339568 |
110 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.57910961 |
111 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.55954753 |
112 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.55471880 |
113 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.55407666 |
114 | Insulin resistance_Homo sapiens_hsa04931 | 0.55081699 |
115 | Glioma_Homo sapiens_hsa05214 | 0.54891167 |
116 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.54597153 |
117 | RNA polymerase_Homo sapiens_hsa03020 | 0.54405249 |
118 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.54207782 |
119 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.53899764 |
120 | Tuberculosis_Homo sapiens_hsa05152 | 0.53095456 |
121 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.52929153 |
122 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.50537377 |
123 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.50007027 |
124 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.49687313 |
125 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.49200716 |
126 | Amoebiasis_Homo sapiens_hsa05146 | 0.48195950 |
127 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.47825144 |
128 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.47781028 |
129 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.46936122 |
130 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.45196691 |
131 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.44168056 |
132 | Influenza A_Homo sapiens_hsa05164 | 0.43865633 |
133 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.43863191 |
134 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.43746831 |
135 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.43219943 |
136 | Hepatitis B_Homo sapiens_hsa05161 | 0.43094863 |
137 | Colorectal cancer_Homo sapiens_hsa05210 | 0.42941270 |
138 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.42812872 |
139 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.42669592 |
140 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.41839686 |
141 | Platelet activation_Homo sapiens_hsa04611 | 0.40224743 |
142 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.39873218 |
143 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.39842977 |
144 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.39256338 |