Rank | Gene Set | Z-score |
---|---|---|
1 | * DNA unwinding involved in DNA replication (GO:0006268) | 5.32362406 |
2 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.75205924 |
3 | protein maturation by protein folding (GO:0022417) | 4.59548809 |
4 | DNA replication initiation (GO:0006270) | 4.58949494 |
5 | DNA strand elongation (GO:0022616) | 4.49242968 |
6 | protein localization to kinetochore (GO:0034501) | 4.47634051 |
7 | folic acid-containing compound biosynthetic process (GO:0009396) | 4.41525412 |
8 | formation of translation preinitiation complex (GO:0001731) | 4.36732552 |
9 | IMP biosynthetic process (GO:0006188) | 4.27877934 |
10 | * establishment of integrated proviral latency (GO:0075713) | 4.20664667 |
11 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.06466687 |
12 | mitotic nuclear envelope disassembly (GO:0007077) | 4.04574585 |
13 | viral transcription (GO:0019083) | 4.00908852 |
14 | maturation of SSU-rRNA (GO:0030490) | 3.96124931 |
15 | translational termination (GO:0006415) | 3.92499336 |
16 | IMP metabolic process (GO:0046040) | 3.87076198 |
17 | membrane disassembly (GO:0030397) | 3.75990676 |
18 | nuclear envelope disassembly (GO:0051081) | 3.75990676 |
19 | nucleobase biosynthetic process (GO:0046112) | 3.74846188 |
20 | ribosomal small subunit assembly (GO:0000028) | 3.70820090 |
21 | protein localization to chromosome, centromeric region (GO:0071459) | 3.70631600 |
22 | translational elongation (GO:0006414) | 3.68513274 |
23 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.67901475 |
24 | nuclear envelope reassembly (GO:0031468) | 3.66430668 |
25 | mitotic nuclear envelope reassembly (GO:0007084) | 3.66430668 |
26 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.62621109 |
27 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.62621109 |
28 | translational initiation (GO:0006413) | 3.61893671 |
29 | nuclear pore organization (GO:0006999) | 3.60180441 |
30 | COPI coating of Golgi vesicle (GO:0048205) | 3.55913316 |
31 | Golgi transport vesicle coating (GO:0048200) | 3.55913316 |
32 | regulation of translational fidelity (GO:0006450) | 3.55116638 |
33 | proline biosynthetic process (GO:0006561) | 3.53583382 |
34 | telomere maintenance via recombination (GO:0000722) | 3.53369066 |
35 | pre-miRNA processing (GO:0031054) | 3.53309599 |
36 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.51398351 |
37 | * establishment of viral latency (GO:0019043) | 3.49612488 |
38 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.49420593 |
39 | negative regulation of RNA splicing (GO:0033119) | 3.48351897 |
40 | * DNA duplex unwinding (GO:0032508) | 3.46610932 |
41 | mitotic metaphase plate congression (GO:0007080) | 3.46262079 |
42 | * DNA geometric change (GO:0032392) | 3.44494907 |
43 | DNA replication checkpoint (GO:0000076) | 3.42847325 |
44 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.41900741 |
45 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.41321291 |
46 | mitotic sister chromatid segregation (GO:0000070) | 3.41072328 |
47 | mitotic recombination (GO:0006312) | 3.39202765 |
48 | nuclear pore complex assembly (GO:0051292) | 3.35343863 |
49 | ribosomal large subunit biogenesis (GO:0042273) | 3.30205437 |
50 | regulation of gene silencing by RNA (GO:0060966) | 3.29060266 |
51 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.29060266 |
52 | regulation of gene silencing by miRNA (GO:0060964) | 3.29060266 |
53 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 3.28508886 |
54 | telomere maintenance via telomere lengthening (GO:0010833) | 3.27478669 |
55 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 3.24613592 |
56 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.23824414 |
57 | ribosomal small subunit biogenesis (GO:0042274) | 3.23366960 |
58 | L-serine metabolic process (GO:0006563) | 3.22266099 |
59 | DNA deamination (GO:0045006) | 3.21549845 |
60 | protein retention in ER lumen (GO:0006621) | 3.20528615 |
61 | pore complex assembly (GO:0046931) | 3.20352207 |
62 | sister chromatid segregation (GO:0000819) | 3.19485359 |
63 | cellular protein complex localization (GO:0034629) | 3.19158648 |
64 | ribosome assembly (GO:0042255) | 3.18514439 |
65 | * heterochromatin organization (GO:0070828) | 3.16833948 |
66 | regulation of histone H3-K9 methylation (GO:0051570) | 3.16684315 |
67 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.16196050 |
68 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.15523181 |
69 | ribosome biogenesis (GO:0042254) | 3.15063002 |
70 | pentose-phosphate shunt (GO:0006098) | 3.13917928 |
71 | cellular protein complex disassembly (GO:0043624) | 3.13288825 |
72 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.11350113 |
73 | negative regulation of mRNA processing (GO:0050686) | 3.11045074 |
74 | protein complex localization (GO:0031503) | 3.10464827 |
75 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.10452272 |
76 | viral life cycle (GO:0019058) | 3.10323657 |
77 | regulation of translational termination (GO:0006449) | 3.09090412 |
78 | regulation of spindle organization (GO:0090224) | 3.05963821 |
79 | purine nucleobase biosynthetic process (GO:0009113) | 3.04599158 |
80 | metaphase plate congression (GO:0051310) | 3.04238764 |
81 | spliceosomal snRNP assembly (GO:0000387) | 3.03805220 |
82 | mRNA splicing, via spliceosome (GO:0000398) | 3.03257602 |
83 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) | 3.03257602 |
84 | RNA splicing, via transesterification reactions (GO:0000375) | 3.02378906 |
85 | positive regulation of DNA-dependent DNA replication (GO:2000105) | 3.02289881 |
86 | protein targeting to ER (GO:0045047) | 3.02105564 |
87 | histone arginine methylation (GO:0034969) | 3.01523097 |
88 | cotranslational protein targeting to membrane (GO:0006613) | 3.00675372 |
89 | mitotic chromosome condensation (GO:0007076) | 2.99608905 |
90 | nucleobase-containing small molecule interconversion (GO:0015949) | 2.99489594 |
91 | * protein complex disassembly (GO:0043241) | 2.98935451 |
92 | positive regulation of chromosome segregation (GO:0051984) | 2.98607856 |
93 | chromosome condensation (GO:0030261) | 2.97512988 |
94 | regulation of protein heterodimerization activity (GO:0043497) | 2.96508634 |
95 | negative regulation of histone methylation (GO:0031061) | 2.96313952 |
96 | nuclear envelope organization (GO:0006998) | 2.95657911 |
97 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 2.95177698 |
98 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 2.93390502 |
99 | translesion synthesis (GO:0019985) | 2.92907379 |
100 | peptidyl-arginine methylation (GO:0018216) | 2.92602040 |
101 | peptidyl-arginine N-methylation (GO:0035246) | 2.92602040 |
102 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 2.89281563 |
103 | NADPH regeneration (GO:0006740) | 2.88261477 |
104 | rRNA processing (GO:0006364) | 2.88000143 |
105 | negative regulation of mRNA metabolic process (GO:1903312) | 2.87993611 |
106 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 2.85445903 |
107 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.81769451 |
108 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 2.81722652 |
109 | establishment of chromosome localization (GO:0051303) | 2.81077839 |
110 | * base-excision repair (GO:0006284) | 2.80873021 |
111 | rRNA metabolic process (GO:0016072) | 2.78091376 |
112 | DNA topological change (GO:0006265) | 2.78042765 |
113 | * macromolecular complex disassembly (GO:0032984) | 2.77904851 |
114 | termination of RNA polymerase II transcription (GO:0006369) | 2.76965815 |
115 | RNA catabolic process (GO:0006401) | 2.75958168 |
116 | protein localization to endoplasmic reticulum (GO:0070972) | 2.75719637 |
117 | * DNA conformation change (GO:0071103) | 2.74813070 |
118 | protein localization to chromosome (GO:0034502) | 2.74371305 |
119 | glucose catabolic process (GO:0006007) | 2.74175110 |
120 | mitotic G1 DNA damage checkpoint (GO:0031571) | 2.73612693 |
121 | convergent extension (GO:0060026) | 2.71497555 |
122 | dosage compensation (GO:0007549) | 2.69514654 |
123 | paraxial mesoderm development (GO:0048339) | 2.68722826 |
124 | mRNA catabolic process (GO:0006402) | 2.68390494 |
125 | postreplication repair (GO:0006301) | 2.68266656 |
126 | regulation of mitotic spindle organization (GO:0060236) | 2.67725442 |
127 | kinetochore organization (GO:0051383) | 2.66209222 |
128 | mRNA stabilization (GO:0048255) | 2.65601492 |
129 | RNA stabilization (GO:0043489) | 2.65601492 |
130 | protein export from nucleus (GO:0006611) | 2.65243241 |
131 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 2.64083486 |
132 | regulation of translational elongation (GO:0006448) | 2.62446787 |
133 | regulation of Wnt signaling pathway involved in heart development (GO:0003307) | 2.61194540 |
134 | * nucleosome disassembly (GO:0006337) | 2.58679352 |
135 | * protein-DNA complex disassembly (GO:0032986) | 2.58679352 |
136 | rRNA transcription (GO:0009303) | 2.56990434 |
137 | regulation of chromosome segregation (GO:0051983) | 2.55991486 |
138 | regulation of cell fate specification (GO:0042659) | 2.55680391 |
139 | mitotic sister chromatid cohesion (GO:0007064) | 2.53782579 |
140 | DNA packaging (GO:0006323) | 2.53266739 |
141 | negative regulation of cell fate specification (GO:0009996) | 2.51800114 |
142 | transcription-coupled nucleotide-excision repair (GO:0006283) | 2.51001263 |
143 | ATP-dependent chromatin remodeling (GO:0043044) | 2.46907760 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 8.42232947 |
2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.19704926 |
3 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.11220659 |
4 | * EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.92265964 |
5 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.27766689 |
6 | * MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.98916914 |
7 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.94473889 |
8 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.86362065 |
9 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.62028700 |
10 | * MYC_22102868_ChIP-Seq_BL_Human | 2.60163689 |
11 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.53045921 |
12 | * XRN2_22483619_ChIP-Seq_HELA_Human | 2.27642049 |
13 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.21582601 |
14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.14321832 |
15 | * NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.11095028 |
16 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.99260297 |
17 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.94167550 |
18 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.91948775 |
19 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.90977723 |
20 | * E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.90250186 |
21 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.88969126 |
22 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.85623382 |
23 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.85581215 |
24 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.80106942 |
25 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.79181851 |
26 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.77549777 |
27 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.70569576 |
28 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.68552036 |
29 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.68546168 |
30 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.66667696 |
31 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.66539023 |
32 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.66162296 |
33 | * NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.62554928 |
34 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.59048585 |
35 | * TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.58850619 |
36 | * VDR_23849224_ChIP-Seq_CD4+_Human | 1.58212302 |
37 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.57316435 |
38 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.57094077 |
39 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.55759024 |
40 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.55342503 |
41 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.53869150 |
42 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.52528964 |
43 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.52357135 |
44 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.50953029 |
45 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.50507566 |
46 | * RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.46447658 |
47 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.45579642 |
48 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.44873668 |
49 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.40431523 |
50 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.39573526 |
51 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.38991368 |
52 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.38718434 |
53 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.38187935 |
54 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.35183182 |
55 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.34729689 |
56 | * DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.31586445 |
57 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.31391639 |
58 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.30711521 |
59 | * ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.30367397 |
60 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.30147832 |
61 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.29179653 |
62 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.28936855 |
63 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.28165559 |
64 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.26584173 |
65 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.25696459 |
66 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.24473375 |
67 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.23676475 |
68 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.23598940 |
69 | * ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.22518504 |
70 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.21583740 |
71 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.20901737 |
72 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.17026721 |
73 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.16336773 |
74 | * KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.14940383 |
75 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.14538482 |
76 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.14420045 |
77 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.12808443 |
78 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.11682335 |
79 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.11553941 |
80 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.10743899 |
81 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.09827133 |
82 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.09056814 |
83 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.07888515 |
84 | * NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.07714981 |
85 | * NCOR1_26117541_ChIP-Seq_K562_Human | 1.07590869 |
86 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.07172479 |
87 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.06836091 |
88 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.06086333 |
89 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.04315642 |
90 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.01738116 |
91 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.01547498 |
92 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.01403077 |
93 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.01173388 |
94 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 1.01033115 |
95 | * P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.00782585 |
96 | * TCF7_22412390_ChIP-Seq_EML_Mouse | 1.00745445 |
97 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.00534404 |
98 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 1.00382981 |
99 | * UTX_26944678_Chip-Seq_JUKART_Human | 0.99531495 |
100 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.97683363 |
101 | * CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.97533120 |
102 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 0.96664034 |
103 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.96146645 |
104 | MAF_26560356_Chip-Seq_TH1_Human | 0.96134023 |
105 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.96073282 |
106 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.95440701 |
107 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.95340281 |
108 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.95303297 |
109 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.95011153 |
110 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.94661320 |
111 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.94477417 |
112 | * TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse | 0.93939825 |
113 | ATF3_27146783_Chip-Seq_COLON_Human | 0.92301853 |
114 | * KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.91978820 |
115 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.91379859 |
116 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.91166847 |
117 | * GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.90655634 |
118 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.90258053 |
119 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.87758037 |
120 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 0.86666612 |
121 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.86645324 |
122 | * TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.86613098 |
123 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.85725597 |
124 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.85725597 |
125 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.85725597 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 4.15108596 |
2 | MP0003111_abnormal_nucleus_morphology | 3.81072939 |
3 | MP0004957_abnormal_blastocyst_morpholog | 3.74272888 |
4 | MP0010094_abnormal_chromosome_stability | 3.68945907 |
5 | MP0003077_abnormal_cell_cycle | 3.44939300 |
6 | MP0010352_gastrointestinal_tract_polyps | 3.23710399 |
7 | MP0008057_abnormal_DNA_replication | 2.83511682 |
8 | MP0002877_abnormal_melanocyte_morpholog | 2.72046503 |
9 | MP0001730_embryonic_growth_arrest | 2.51630366 |
10 | MP0008007_abnormal_cellular_replicative | 2.50967699 |
11 | MP0010030_abnormal_orbit_morphology | 2.49280150 |
12 | MP0003123_paternal_imprinting | 2.34604997 |
13 | MP0000350_abnormal_cell_proliferation | 2.31733121 |
14 | MP0002254_reproductive_system_inflammat | 2.28068730 |
15 | MP0008932_abnormal_embryonic_tissue | 2.24997768 |
16 | MP0005257_abnormal_intraocular_pressure | 2.20497046 |
17 | MP0008058_abnormal_DNA_repair | 2.20121964 |
18 | MP0010307_abnormal_tumor_latency | 2.17970609 |
19 | MP0002396_abnormal_hematopoietic_system | 2.17288360 |
20 | MP0004272_abnormal_basement_membrane | 2.09191213 |
21 | MP0003705_abnormal_hypodermis_morpholog | 2.09023872 |
22 | MP0005076_abnormal_cell_differentiation | 2.02957735 |
23 | MP0004808_abnormal_hematopoietic_stem | 1.89419524 |
24 | MP0004185_abnormal_adipocyte_glucose | 1.88906553 |
25 | MP0001697_abnormal_embryo_size | 1.81981348 |
26 | MP0001672_abnormal_embryogenesis/_devel | 1.81311483 |
27 | MP0005380_embryogenesis_phenotype | 1.81311483 |
28 | MP0009278_abnormal_bone_marrow | 1.72632291 |
29 | MP0002085_abnormal_embryonic_tissue | 1.70719462 |
30 | MP0004197_abnormal_fetal_growth/weight/ | 1.69959364 |
31 | MP0000490_abnormal_crypts_of | 1.69598846 |
32 | MP0003984_embryonic_growth_retardation | 1.69417027 |
33 | MP0000537_abnormal_urethra_morphology | 1.69092377 |
34 | MP0002796_impaired_skin_barrier | 1.67810178 |
35 | MP0002088_abnormal_embryonic_growth/wei | 1.66499294 |
36 | MP0002080_prenatal_lethality | 1.65493619 |
37 | MP0002084_abnormal_developmental_patter | 1.65091910 |
38 | MP0009053_abnormal_anal_canal | 1.62354190 |
39 | MP0008877_abnormal_DNA_methylation | 1.55893631 |
40 | MP0009697_abnormal_copulation | 1.51996412 |
41 | MP0005451_abnormal_body_composition | 1.51375569 |
42 | MP0002086_abnormal_extraembryonic_tissu | 1.50629490 |
43 | MP0004858_abnormal_nervous_system | 1.48536753 |
44 | MP0010234_abnormal_vibrissa_follicle | 1.48097162 |
45 | MP0003890_abnormal_embryonic-extraembry | 1.43574323 |
46 | MP0000313_abnormal_cell_death | 1.41276532 |
47 | MP0003566_abnormal_cell_adhesion | 1.38429002 |
48 | * MP0002019_abnormal_tumor_incidence | 1.36967038 |
49 | MP0001545_abnormal_hematopoietic_system | 1.33354010 |
50 | MP0005397_hematopoietic_system_phenotyp | 1.33354010 |
51 | MP0003119_abnormal_digestive_system | 1.32634053 |
52 | MP0003718_maternal_effect | 1.31418661 |
53 | MP0005023_abnormal_wound_healing | 1.31208428 |
54 | MP0009333_abnormal_splenocyte_physiolog | 1.29236689 |
55 | MP0001293_anophthalmia | 1.29096867 |
56 | MP0000751_myopathy | 1.28014289 |
57 | MP0001299_abnormal_eye_distance/ | 1.27384042 |
58 | MP0001849_ear_inflammation | 1.23749168 |
59 | MP0009672_abnormal_birth_weight | 1.22644333 |
60 | MP0002653_abnormal_ependyma_morphology | 1.22561157 |
61 | MP0003121_genomic_imprinting | 1.20257264 |
62 | MP0000703_abnormal_thymus_morphology | 1.19846175 |
63 | MP0000858_altered_metastatic_potential | 1.16396582 |
64 | MP0003567_abnormal_fetal_cardiomyocyte | 1.12486810 |
65 | MP0004133_heterotaxia | 1.10267269 |
66 | MP0002111_abnormal_tail_morphology | 1.09660123 |
67 | MP0000733_abnormal_muscle_development | 1.07141966 |
68 | MP0000566_synostosis | 1.06265692 |
69 | MP0003303_peritoneal_inflammation | 1.06097465 |
70 | MP0002398_abnormal_bone_marrow | 1.05883670 |
71 | MP0001915_intracranial_hemorrhage | 1.05553076 |
72 | MP0000762_abnormal_tongue_morphology | 1.03757083 |
73 | MP0003283_abnormal_digestive_organ | 1.02632596 |
74 | * MP0002722_abnormal_immune_system | 1.02098613 |
75 | MP0000678_abnormal_parathyroid_gland | 1.01937696 |
76 | MP0003786_premature_aging | 1.01641775 |
77 | MP0006054_spinal_hemorrhage | 1.01537479 |
78 | MP0004233_abnormal_muscle_weight | 1.01031198 |
79 | MP0003950_abnormal_plasma_membrane | 1.00413728 |
80 | MP0003385_abnormal_body_wall | 0.99825659 |
81 | MP0002060_abnormal_skin_morphology | 0.99011455 |
82 | MP0005623_abnormal_meninges_morphology | 0.96614058 |
83 | MP0003942_abnormal_urinary_system | 0.95514695 |
84 | MP0000428_abnormal_craniofacial_morphol | 0.94742924 |
85 | MP0002089_abnormal_postnatal_growth/wei | 0.91332304 |
86 | MP0009703_decreased_birth_body | 0.90944477 |
87 | MP0003315_abnormal_perineum_morphology | 0.89619080 |
88 | * MP0000689_abnormal_spleen_morphology | 0.88702681 |
89 | MP0000003_abnormal_adipose_tissue | 0.87990754 |
90 | MP0004264_abnormal_extraembryonic_tissu | 0.87007240 |
91 | MP0002925_abnormal_cardiovascular_devel | 0.82618926 |
92 | MP0005621_abnormal_cell_physiology | 0.81798578 |
93 | MP0008260_abnormal_autophagy | 0.81311633 |
94 | MP0005384_cellular_phenotype | 0.79966536 |
95 | MP0001216_abnormal_epidermal_layer | 0.79885819 |
96 | * MP0002429_abnormal_blood_cell | 0.79734636 |
97 | MP0000358_abnormal_cell_content/ | 0.79329883 |
98 | MP0003221_abnormal_cardiomyocyte_apopto | 0.78551170 |
99 | MP0010630_abnormal_cardiac_muscle | 0.77346608 |
100 | MP0003436_decreased_susceptibility_to | 0.77176479 |
101 | MP0000477_abnormal_intestine_morphology | 0.76992206 |
102 | MP0002092_abnormal_eye_morphology | 0.75789887 |
103 | MP0005501_abnormal_skin_physiology | 0.75767181 |
104 | MP0008770_decreased_survivor_rate | 0.75396356 |
105 | MP0003763_abnormal_thymus_physiology | 0.75343129 |
106 | MP0003448_altered_tumor_morphology | 0.75199722 |
107 | MP0002697_abnormal_eye_size | 0.74632903 |
108 | MP0005666_abnormal_adipose_tissue | 0.74499876 |
109 | MP0003937_abnormal_limbs/digits/tail_de | 0.74274010 |
110 | MP0001661_extended_life_span | 0.73786673 |
111 | MP0000432_abnormal_head_morphology | 0.73704085 |
112 | MP0005197_abnormal_uvea_morphology | 0.73532867 |
113 | MP0000534_abnormal_ureter_morphology | 0.73259600 |
114 | MP0003091_abnormal_cell_migration | 0.72582126 |
115 | MP0006292_abnormal_olfactory_placode | 0.72437052 |
116 | MP0001340_abnormal_eyelid_morphology | 0.72259600 |
117 | MP0003115_abnormal_respiratory_system | 0.70289595 |
118 | MP0003941_abnormal_skin_development | 0.68215240 |
119 | MP0008789_abnormal_olfactory_epithelium | 0.68202078 |
120 | MP0000750_abnormal_muscle_regeneration | 0.67359918 |
121 | MP0002932_abnormal_joint_morphology | 0.66869233 |
122 | * MP0000716_abnormal_immune_system | 0.66505676 |
123 | MP0000685_abnormal_immune_system | 0.66246061 |
124 | MP0001286_abnormal_eye_development | 0.65626707 |
125 | MP0002282_abnormal_trachea_morphology | 0.65128719 |
126 | MP0002405_respiratory_system_inflammati | 0.62718069 |
127 | MP0000049_abnormal_middle_ear | 0.60948379 |
128 | MP0003935_abnormal_craniofacial_develop | 0.60460171 |
129 | MP0001853_heart_inflammation | 0.57998765 |
130 | * MP0000266_abnormal_heart_morphology | 0.57731094 |
131 | MP0002452_abnormal_antigen_presenting | 0.55574156 |
132 | MP0003861_abnormal_nervous_system | 0.55274716 |
133 | MP0003453_abnormal_keratinocyte_physiol | 0.53648463 |
134 | * MP0001145_abnormal_male_reproductive | 0.53117952 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Selective tooth agenesis (HP:0001592) | 3.69121269 |
2 | Reticulocytopenia (HP:0001896) | 3.61126974 |
3 | Colon cancer (HP:0003003) | 3.56610746 |
4 | Premature rupture of membranes (HP:0001788) | 3.28112983 |
5 | Insomnia (HP:0100785) | 3.18862157 |
6 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.12799195 |
7 | Oral leukoplakia (HP:0002745) | 3.04994173 |
8 | Birth length less than 3rd percentile (HP:0003561) | 3.04839714 |
9 | Ependymoma (HP:0002888) | 3.01814226 |
10 | Medulloblastoma (HP:0002885) | 3.01689649 |
11 | Degeneration of anterior horn cells (HP:0002398) | 2.98286105 |
12 | Abnormality of the anterior horn cell (HP:0006802) | 2.98286105 |
13 | Distal lower limb amyotrophy (HP:0008944) | 2.92759874 |
14 | Abnormal number of incisors (HP:0011064) | 2.91932235 |
15 | Achilles tendon contracture (HP:0001771) | 2.88820950 |
16 | Upper limb muscle weakness (HP:0003484) | 2.86343718 |
17 | Abnormal number of erythroid precursors (HP:0012131) | 2.84230332 |
18 | Trismus (HP:0000211) | 2.79458658 |
19 | Patellar aplasia (HP:0006443) | 2.73220702 |
20 | Progressive muscle weakness (HP:0003323) | 2.72606508 |
21 | Cholecystitis (HP:0001082) | 2.71383927 |
22 | Abnormal gallbladder physiology (HP:0012438) | 2.71383927 |
23 | Agnosia (HP:0010524) | 2.69890284 |
24 | Long palpebral fissure (HP:0000637) | 2.64535045 |
25 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.58350930 |
26 | Breast hypoplasia (HP:0003187) | 2.55871359 |
27 | Deviation of the thumb (HP:0009603) | 2.54012245 |
28 | Increased nuchal translucency (HP:0010880) | 2.52348122 |
29 | Overriding aorta (HP:0002623) | 2.52143501 |
30 | Short 4th metacarpal (HP:0010044) | 2.52142279 |
31 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.52142279 |
32 | Proximal placement of thumb (HP:0009623) | 2.50952704 |
33 | Aplastic anemia (HP:0001915) | 2.50931309 |
34 | Basal cell carcinoma (HP:0002671) | 2.50808581 |
35 | Absent thumb (HP:0009777) | 2.49577511 |
36 | Spastic diplegia (HP:0001264) | 2.48956521 |
37 | Shoulder girdle muscle weakness (HP:0003547) | 2.45311988 |
38 | Increased connective tissue (HP:0009025) | 2.44872153 |
39 | Abnormality of the Achilles tendon (HP:0005109) | 2.42752381 |
40 | Lower limb amyotrophy (HP:0007210) | 2.42722767 |
41 | Distal upper limb amyotrophy (HP:0007149) | 2.41751494 |
42 | Upper limb amyotrophy (HP:0009129) | 2.41751494 |
43 | Increased density of long bones (HP:0006392) | 2.36760924 |
44 | High anterior hairline (HP:0009890) | 2.35732731 |
45 | Entropion (HP:0000621) | 2.34646509 |
46 | Pelvic girdle muscle weakness (HP:0003749) | 2.33722791 |
47 | Rough bone trabeculation (HP:0100670) | 2.32639903 |
48 | Hyperacusis (HP:0010780) | 2.32313792 |
49 | Atresia of the external auditory canal (HP:0000413) | 2.31664529 |
50 | Renal duplication (HP:0000075) | 2.30467208 |
51 | Cortical dysplasia (HP:0002539) | 2.30299365 |
52 | Neoplasm of the pancreas (HP:0002894) | 2.29983566 |
53 | Missing ribs (HP:0000921) | 2.29630722 |
54 | Rhabdomyosarcoma (HP:0002859) | 2.29347752 |
55 | Spinal rigidity (HP:0003306) | 2.28259748 |
56 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.28243141 |
57 | Disproportionate tall stature (HP:0001519) | 2.28000278 |
58 | Carpal bone hypoplasia (HP:0001498) | 2.25988039 |
59 | Difficulty climbing stairs (HP:0003551) | 2.23528929 |
60 | Pallor (HP:0000980) | 2.20968370 |
61 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.19582281 |
62 | Skin tags (HP:0010609) | 2.19199959 |
63 | Preauricular skin tag (HP:0000384) | 2.17371423 |
64 | High pitched voice (HP:0001620) | 2.17261915 |
65 | Arnold-Chiari malformation (HP:0002308) | 2.16635539 |
66 | Short nail (HP:0001799) | 2.14558470 |
67 | Abnormality of the calcaneus (HP:0008364) | 2.13156372 |
68 | Tracheoesophageal fistula (HP:0002575) | 2.13020119 |
69 | Vertebral compression fractures (HP:0002953) | 2.12497440 |
70 | Shallow orbits (HP:0000586) | 2.12023790 |
71 | Natal tooth (HP:0000695) | 2.10600017 |
72 | Absent radius (HP:0003974) | 2.10502280 |
73 | Distal lower limb muscle weakness (HP:0009053) | 2.08686100 |
74 | Thrombocytosis (HP:0001894) | 2.08513503 |
75 | Cellular immunodeficiency (HP:0005374) | 2.07530278 |
76 | Macrocytic anemia (HP:0001972) | 2.07020201 |
77 | Ectopic kidney (HP:0000086) | 2.06617644 |
78 | Multiple enchondromatosis (HP:0005701) | 2.06461064 |
79 | Chromsome breakage (HP:0040012) | 2.05832182 |
80 | Abnormality of abdominal situs (HP:0011620) | 2.05285870 |
81 | Abdominal situs inversus (HP:0003363) | 2.05285870 |
82 | Abnormality of the astrocytes (HP:0100707) | 2.02757484 |
83 | Astrocytoma (HP:0009592) | 2.02757484 |
84 | Neoplasm of striated muscle (HP:0009728) | 2.02305321 |
85 | 11 pairs of ribs (HP:0000878) | 2.02224657 |
86 | Elfin facies (HP:0004428) | 2.02057245 |
87 | Squamous cell carcinoma (HP:0002860) | 2.01165194 |
88 | Angiofibromas (HP:0010615) | 2.01153738 |
89 | Adenoma sebaceum (HP:0009720) | 2.01153738 |
90 | Overlapping toe (HP:0001845) | 2.00961936 |
91 | Hand muscle atrophy (HP:0009130) | 2.00619865 |
92 | Premature graying of hair (HP:0002216) | 2.00043511 |
93 | Rib fusion (HP:0000902) | 1.99894609 |
94 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.99120364 |
95 | Osteolytic defects of the hand bones (HP:0009699) | 1.99120364 |
96 | Ankyloglossia (HP:0010296) | 1.98733580 |
97 | Long eyelashes (HP:0000527) | 1.98550560 |
98 | Myelodysplasia (HP:0002863) | 1.98500519 |
99 | Reduced subcutaneous adipose tissue (HP:0003758) | 1.95745866 |
100 | Abnormality of the umbilical cord (HP:0010881) | 1.94856343 |
101 | Poikiloderma (HP:0001029) | 1.93761798 |
102 | Absent forearm bone (HP:0003953) | 1.93470204 |
103 | Aplasia involving forearm bones (HP:0009822) | 1.93470204 |
104 | Cutaneous melanoma (HP:0012056) | 1.92893935 |
105 | Ulnar bowing (HP:0003031) | 1.91117410 |
106 | Microretrognathia (HP:0000308) | 1.90966918 |
107 | Abnormality of reticulocytes (HP:0004312) | 1.90512550 |
108 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.89941669 |
109 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.89941669 |
110 | Abnormality of oral frenula (HP:0000190) | 1.89568728 |
111 | Urethral obstruction (HP:0000796) | 1.88707606 |
112 | Glossoptosis (HP:0000162) | 1.87042702 |
113 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.86713324 |
114 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.86310801 |
115 | Asplenia (HP:0001746) | 1.86059142 |
116 | Orthostatic hypotension (HP:0001278) | 1.85877740 |
117 | Syringomyelia (HP:0003396) | 1.83677599 |
118 | Spinal cord lesions (HP:0100561) | 1.83677599 |
119 | Pointed chin (HP:0000307) | 1.83382588 |
120 | Protrusio acetabuli (HP:0003179) | 1.83303148 |
121 | Esophageal atresia (HP:0002032) | 1.82916519 |
122 | Generalized amyotrophy (HP:0003700) | 1.82834909 |
123 | Midface retrusion (HP:0011800) | 1.82816479 |
124 | Neoplasm of the oral cavity (HP:0100649) | 1.82717517 |
125 | Meckel diverticulum (HP:0002245) | 1.82356130 |
126 | Aplasia involving bones of the extremities (HP:0009825) | 1.80364923 |
127 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.80364923 |
128 | Aplasia of the phalanges of the hand (HP:0009802) | 1.80364923 |
129 | Facial cleft (HP:0002006) | 1.79878430 |
130 | Abnormal lung lobation (HP:0002101) | 1.79852923 |
131 | Progressive hearing impairment (HP:0001730) | 1.79554555 |
132 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.79236703 |
133 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.78847285 |
134 | Gastrointestinal carcinoma (HP:0002672) | 1.78847285 |
135 | Rectal prolapse (HP:0002035) | 1.78487119 |
136 | Slender long bone (HP:0003100) | 1.78217956 |
137 | Aplasia/Hypoplasia of the breasts (HP:0010311) | 1.77484170 |
138 | Microglossia (HP:0000171) | 1.77279056 |
139 | Acute lymphatic leukemia (HP:0006721) | 1.75573234 |
140 | Abnormality of the ileum (HP:0001549) | 1.75332463 |
141 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.75224845 |
142 | Amaurosis fugax (HP:0100576) | 1.73696955 |
143 | Abnormality of subcutaneous fat tissue (HP:0001001) | 1.73624720 |
144 | Progressive external ophthalmoplegia (HP:0000590) | 1.73503457 |
145 | Abnormality of chromosome stability (HP:0003220) | 1.73325905 |
146 | Duplication of thumb phalanx (HP:0009942) | 1.72533329 |
147 | Supernumerary spleens (HP:0009799) | 1.71210415 |
148 | Trigonocephaly (HP:0000243) | 1.70648941 |
149 | Abnormality of the 4th metacarpal (HP:0010012) | 1.70430502 |
150 | Cleft eyelid (HP:0000625) | 1.69674214 |
151 | Aplasia/hypoplasia of the humerus (HP:0006507) | 1.69341880 |
152 | Bone marrow hypocellularity (HP:0005528) | 1.69058035 |
153 | Cellulitis (HP:0100658) | 1.68429931 |
154 | Genu recurvatum (HP:0002816) | 1.68424947 |
155 | Horseshoe kidney (HP:0000085) | 1.67391005 |
156 | Small intestinal stenosis (HP:0012848) | 1.67369520 |
157 | Duodenal stenosis (HP:0100867) | 1.67369520 |
158 | Limb-girdle muscle atrophy (HP:0003797) | 1.66754131 |
159 | Abnormality of the preputium (HP:0100587) | 1.65854705 |
160 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.65634681 |
161 | Spinal muscular atrophy (HP:0007269) | 1.65581849 |
162 | Cafe-au-lait spot (HP:0000957) | 1.65038803 |
163 | Bronchomalacia (HP:0002780) | 1.64518834 |
164 | Ankle contracture (HP:0006466) | 1.63434006 |
165 | Skull defect (HP:0001362) | 1.63139734 |
166 | Reticulocytosis (HP:0001923) | 1.63038667 |
167 | Broad distal phalanx of finger (HP:0009836) | 1.62566705 |
168 | Abnormal trabecular bone morphology (HP:0100671) | 1.62324537 |
169 | Choanal stenosis (HP:0000452) | 1.62266083 |
170 | Secondary amenorrhea (HP:0000869) | 1.61686088 |
171 | Breast aplasia (HP:0100783) | 1.60029346 |
172 | Patellar dislocation (HP:0002999) | 1.59698887 |
173 | Broad face (HP:0000283) | 1.59680469 |
174 | Delayed cranial suture closure (HP:0000270) | 1.58655310 |
175 | Breech presentation (HP:0001623) | 1.58234572 |
176 | Myocardial infarction (HP:0001658) | 1.58161171 |
177 | Back pain (HP:0003418) | 1.56734157 |
178 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.56530893 |
179 | Pseudobulbar signs (HP:0002200) | 1.56389195 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CDC7 | 3.92577168 |
2 | VRK2 | 3.56218381 |
3 | BUB1 | 3.48863637 |
4 | MAP3K10 | 3.42660005 |
5 | EEF2K | 3.38683119 |
6 | SMG1 | 3.31971185 |
7 | WEE1 | 2.99876895 |
8 | PKN2 | 2.77765760 |
9 | IRAK3 | 2.56559635 |
10 | NEK2 | 2.55695767 |
11 | TESK2 | 2.41778076 |
12 | CDK12 | 2.40986738 |
13 | TRIB3 | 2.07764178 |
14 | TSSK6 | 2.03980681 |
15 | STK10 | 1.94917201 |
16 | PASK | 1.94666194 |
17 | RPS6KA4 | 1.93164253 |
18 | NEK1 | 1.83290391 |
19 | MST1R | 1.79422293 |
20 | TTK | 1.79079336 |
21 | CDK7 | 1.75115059 |
22 | PAK4 | 1.72478726 |
23 | MAP3K8 | 1.70703470 |
24 | RPS6KB2 | 1.65055247 |
25 | ERBB4 | 1.61611305 |
26 | SCYL2 | 1.59801843 |
27 | ARAF | 1.54166876 |
28 | EIF2AK1 | 1.53444768 |
29 | MKNK1 | 1.53258717 |
30 | CDK4 | 1.50273475 |
31 | TAF1 | 1.50158412 |
32 | EPHA2 | 1.49219366 |
33 | LMTK2 | 1.48168922 |
34 | PLK1 | 1.47389012 |
35 | ATR | 1.45107744 |
36 | LRRK2 | 1.44931898 |
37 | NME2 | 1.40770627 |
38 | TGFBR1 | 1.39970478 |
39 | TESK1 | 1.39862933 |
40 | MET | 1.36605590 |
41 | AURKB | 1.36190697 |
42 | PRPF4B | 1.28508846 |
43 | SIK1 | 1.25152350 |
44 | MAP3K11 | 1.24996088 |
45 | ERN1 | 1.24427135 |
46 | SRPK1 | 1.23799173 |
47 | MAP4K1 | 1.23581261 |
48 | FLT3 | 1.16912768 |
49 | DYRK3 | 1.11886555 |
50 | MAP2K3 | 1.11652726 |
51 | CHEK1 | 1.11082606 |
52 | BRAF | 1.10229333 |
53 | BRSK2 | 1.10052533 |
54 | PIM2 | 1.09771724 |
55 | PBK | 1.07542066 |
56 | ALK | 1.07133345 |
57 | STK4 | 1.06750457 |
58 | AURKA | 1.03328374 |
59 | CDK6 | 1.02365580 |
60 | BRD4 | 1.01993320 |
61 | GRK6 | 1.01195118 |
62 | DAPK1 | 0.99352210 |
63 | LATS2 | 0.95777849 |
64 | BMX | 0.92375254 |
65 | CHEK2 | 0.92296801 |
66 | NTRK1 | 0.90264410 |
67 | ACVR1B | 0.89031814 |
68 | PLK4 | 0.88559595 |
69 | KDR | 0.88515769 |
70 | TLK1 | 0.85773321 |
71 | PLK3 | 0.84834020 |
72 | PTK6 | 0.84056720 |
73 | MTOR | 0.83023474 |
74 | * CDK2 | 0.82888113 |
75 | MOS | 0.82219796 |
76 | PAK1 | 0.81189745 |
77 | PIM1 | 0.80189094 |
78 | MAP3K9 | 0.79590734 |
79 | BTK | 0.79104032 |
80 | DMPK | 0.78223176 |
81 | TTN | 0.75436276 |
82 | BRSK1 | 0.75285487 |
83 | CDK19 | 0.75095295 |
84 | MKNK2 | 0.74314458 |
85 | PAK2 | 0.73966663 |
86 | EIF2AK3 | 0.72804005 |
87 | ICK | 0.72391017 |
88 | * ATM | 0.67012536 |
89 | AKT2 | 0.65403687 |
90 | FGFR1 | 0.63661450 |
91 | EPHB1 | 0.63141687 |
92 | VRK1 | 0.59719132 |
93 | PRKG2 | 0.58869948 |
94 | LIMK1 | 0.57378812 |
95 | STK3 | 0.55578248 |
96 | CDK11A | 0.54680619 |
97 | EIF2AK2 | 0.54142354 |
98 | * CSNK2A2 | 0.53572028 |
99 | CLK1 | 0.52994946 |
100 | ILK | 0.52516558 |
101 | EPHB2 | 0.51329099 |
102 | MAP3K3 | 0.50497500 |
103 | CDK15 | 0.50220975 |
104 | * CDK1 | 0.49499191 |
105 | CDK18 | 0.48463371 |
106 | * CSNK2A1 | 0.47639615 |
107 | CDK14 | 0.47594662 |
108 | MST4 | 0.47444490 |
109 | CDK8 | 0.47431680 |
110 | CDK9 | 0.44909115 |
111 | PDGFRA | 0.44707344 |
112 | MAP2K2 | 0.43866291 |
113 | FGFR4 | 0.43448301 |
114 | ABL2 | 0.42443366 |
115 | TAOK2 | 0.42218653 |
116 | MAPKAPK3 | 0.41833099 |
117 | ZAP70 | 0.41814372 |
118 | MELK | 0.41534731 |
119 | MAPKAPK2 | 0.41276835 |
120 | BLK | 0.41162766 |
121 | TAOK1 | 0.40225437 |
122 | CAMK1D | 0.39079762 |
123 | CSNK1E | 0.39073956 |
124 | DYRK1B | 0.37559022 |
125 | STK16 | 0.36123485 |
126 | LATS1 | 0.36077674 |
127 | RPS6KA1 | 0.33554076 |
128 | RIPK1 | 0.27803589 |
129 | CSF1R | 0.27663753 |
130 | AKT1 | 0.26983120 |
131 | CHUK | 0.26912491 |
132 | PTK2 | 0.26665368 |
133 | PRKCI | 0.26034798 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 4.86887979 |
2 | Mismatch repair_Homo sapiens_hsa03430 | 3.92884286 |
3 | Spliceosome_Homo sapiens_hsa03040 | 3.35937480 |
4 | Ribosome_Homo sapiens_hsa03010 | 3.10588679 |
5 | Base excision repair_Homo sapiens_hsa03410 | 3.06815610 |
6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.04128033 |
7 | RNA transport_Homo sapiens_hsa03013 | 3.00351420 |
8 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.88720313 |
9 | Cell cycle_Homo sapiens_hsa04110 | 2.66845984 |
10 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.50761615 |
11 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.39916839 |
12 | Homologous recombination_Homo sapiens_hsa03440 | 2.36569553 |
13 | RNA polymerase_Homo sapiens_hsa03020 | 2.19348115 |
14 | Proteasome_Homo sapiens_hsa03050 | 2.12873464 |
15 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.94078422 |
16 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.86914312 |
17 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.81782161 |
18 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.72281033 |
19 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.72118926 |
20 | RNA degradation_Homo sapiens_hsa03018 | 1.67331971 |
21 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.49879239 |
22 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.23046192 |
23 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.23006807 |
24 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.21490722 |
25 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.18112060 |
26 | Thyroid cancer_Homo sapiens_hsa05216 | 1.17616522 |
27 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.13813434 |
28 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.12555321 |
29 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.11346833 |
30 | HTLV-I infection_Homo sapiens_hsa05166 | 1.09671624 |
31 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.05934685 |
32 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.05840704 |
33 | Basal transcription factors_Homo sapiens_hsa03022 | 1.02994856 |
34 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.01398749 |
35 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.99321939 |
36 | Bladder cancer_Homo sapiens_hsa05219 | 0.98208194 |
37 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.93587180 |
38 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.93322259 |
39 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.93148876 |
40 | Shigellosis_Homo sapiens_hsa05131 | 0.89840215 |
41 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.89053063 |
42 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.88692312 |
43 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.87972404 |
44 | Legionellosis_Homo sapiens_hsa05134 | 0.87513185 |
45 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.86246875 |
46 | Apoptosis_Homo sapiens_hsa04210 | 0.85987630 |
47 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.85548208 |
48 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.84752878 |
49 | Colorectal cancer_Homo sapiens_hsa05210 | 0.82707600 |
50 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.82152057 |
51 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.80155309 |
52 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.79807665 |
53 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.79423593 |
54 | Purine metabolism_Homo sapiens_hsa00230 | 0.79221506 |
55 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.78653737 |
56 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.78453717 |
57 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.77295614 |
58 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.75597671 |
59 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.75435276 |
60 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.73416368 |
61 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.70686095 |
62 | Focal adhesion_Homo sapiens_hsa04510 | 0.70474162 |
63 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.69884671 |
64 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.68091082 |
65 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.66913575 |
66 | Hepatitis B_Homo sapiens_hsa05161 | 0.65951396 |
67 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.65067216 |
68 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.64936015 |
69 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.64355087 |
70 | Viral myocarditis_Homo sapiens_hsa05416 | 0.63417924 |
71 | Tight junction_Homo sapiens_hsa04530 | 0.61772148 |
72 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.61619459 |
73 | Leishmaniasis_Homo sapiens_hsa05140 | 0.61196764 |
74 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.61061821 |
75 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.60831514 |
76 | Adherens junction_Homo sapiens_hsa04520 | 0.59777632 |
77 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.59694720 |
78 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.57880861 |
79 | Sulfur relay system_Homo sapiens_hsa04122 | 0.56760039 |
80 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.56573203 |
81 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.56324292 |
82 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.56103209 |
83 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.54152413 |
84 | Measles_Homo sapiens_hsa05162 | 0.52169818 |
85 | Pathways in cancer_Homo sapiens_hsa05200 | 0.51502071 |
86 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.50695757 |
87 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.50015625 |
88 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.49806237 |
89 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.49747242 |
90 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.49003161 |
91 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.48714775 |
92 | Carbon metabolism_Homo sapiens_hsa01200 | 0.48662815 |
93 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.48616672 |
94 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.48557914 |
95 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.48122554 |
96 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.46726075 |
97 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.45932707 |
98 | Prion diseases_Homo sapiens_hsa05020 | 0.45672071 |
99 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.44117564 |
100 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.42440357 |
101 | Prostate cancer_Homo sapiens_hsa05215 | 0.42313315 |
102 | Melanoma_Homo sapiens_hsa05218 | 0.42308535 |
103 | Influenza A_Homo sapiens_hsa05164 | 0.42057863 |
104 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.41965603 |
105 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.41666925 |
106 | Endometrial cancer_Homo sapiens_hsa05213 | 0.41436332 |
107 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.39418132 |
108 | Salmonella infection_Homo sapiens_hsa05132 | 0.38585597 |
109 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.38074476 |
110 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.37786616 |
111 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.37302750 |
112 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.36168038 |
113 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.36083248 |
114 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.34282739 |
115 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.33649895 |
116 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.31655417 |
117 | Galactose metabolism_Homo sapiens_hsa00052 | 0.31401690 |
118 | Lysine degradation_Homo sapiens_hsa00310 | 0.30162976 |
119 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.27661148 |
120 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.26869836 |
121 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.26682043 |
122 | Glioma_Homo sapiens_hsa05214 | 0.26465874 |
123 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.26432009 |
124 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.26213267 |
125 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.26027732 |