

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | protein retention in ER lumen (GO:0006621) | 6.50616131 |
| 2 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 6.48747258 |
| 3 | peptidyl-proline hydroxylation (GO:0019511) | 5.66763212 |
| 4 | protein hydroxylation (GO:0018126) | 5.24277866 |
| 5 | C21-steroid hormone biosynthetic process (GO:0006700) | 4.72791690 |
| 6 | cellular response to zinc ion (GO:0071294) | 4.44831572 |
| 7 | cranial suture morphogenesis (GO:0060363) | 4.21121541 |
| 8 | G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:0007199 | 4.20532618 |
| 9 | 4-hydroxyproline metabolic process (GO:0019471) | 4.14718820 |
| 10 | regulation of chromatin binding (GO:0035561) | 4.08218795 |
| 11 | endosome to melanosome transport (GO:0035646) | 4.02666912 |
| 12 | endosome to pigment granule transport (GO:0043485) | 4.02666912 |
| 13 | nucleotide-sugar biosynthetic process (GO:0009226) | 3.99299172 |
| 14 | negative regulation of fatty acid biosynthetic process (GO:0045717) | 3.90725148 |
| 15 | regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768) | 3.75123007 |
| 16 | histone H4 deacetylation (GO:0070933) | 3.73497820 |
| 17 | negative regulation of myotube differentiation (GO:0010832) | 3.71398654 |
| 18 | regulation of somitogenesis (GO:0014807) | 3.69271954 |
| 19 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 3.66519412 |
| 20 | embryonic skeletal joint morphogenesis (GO:0060272) | 3.63143958 |
| 21 | cholesterol biosynthetic process (GO:0006695) | 3.55762127 |
| 22 | mRNA cleavage (GO:0006379) | 3.54451988 |
| 23 | pre-miRNA processing (GO:0031054) | 3.53793177 |
| 24 | L-ascorbic acid metabolic process (GO:0019852) | 3.53121328 |
| 25 | keratinocyte proliferation (GO:0043616) | 3.52764242 |
| 26 | regulation of podosome assembly (GO:0071801) | 3.51791417 |
| 27 | regulation of female gonad development (GO:2000194) | 3.50598502 |
| 28 | COPII vesicle coating (GO:0048208) | 3.48481150 |
| 29 | negative regulation of vascular permeability (GO:0043116) | 3.46736369 |
| 30 | corticosteroid receptor signaling pathway (GO:0031958) | 3.46267742 |
| 31 | xenobiotic catabolic process (GO:0042178) | 3.45039931 |
| 32 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.34429251 |
| 33 | cellular response to glucose starvation (GO:0042149) | 3.31855244 |
| 34 | Golgi transport vesicle coating (GO:0048200) | 3.27427058 |
| 35 | COPI coating of Golgi vesicle (GO:0048205) | 3.27427058 |
| 36 | hyaluronan catabolic process (GO:0030214) | 3.26826396 |
| 37 | protein maturation by protein folding (GO:0022417) | 3.19447907 |
| 38 | short-term memory (GO:0007614) | 3.19092883 |
| 39 | glucocorticoid receptor signaling pathway (GO:0042921) | 3.18757736 |
| 40 | heterochromatin organization (GO:0070828) | 3.18666041 |
| 41 | modification by host of symbiont morphology or physiology (GO:0051851) | 3.15472668 |
| 42 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 3.14600629 |
| 43 | GDP-mannose metabolic process (GO:0019673) | 3.14323726 |
| 44 | iron ion import (GO:0097286) | 3.11222151 |
| 45 | intra-S DNA damage checkpoint (GO:0031573) | 3.11091209 |
| 46 | regulation of translational termination (GO:0006449) | 3.08063995 |
| 47 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.06870930 |
| 48 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.06870930 |
| 49 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.06870930 |
| 50 | positive regulation of steroid hormone secretion (GO:2000833) | 3.05336221 |
| 51 | eyelid development in camera-type eye (GO:0061029) | 3.05139479 |
| 52 | DNA integration (GO:0015074) | 3.05029007 |
| 53 | modulation by host of viral transcription (GO:0043921) | 3.04234794 |
| 54 | modulation by host of symbiont transcription (GO:0052472) | 3.04234794 |
| 55 | cellular response to cadmium ion (GO:0071276) | 3.03603601 |
| 56 | mannosylation (GO:0097502) | 3.01426277 |
| 57 | telomere maintenance via telomerase (GO:0007004) | 3.00402044 |
| 58 | progesterone metabolic process (GO:0042448) | 2.99319626 |
| 59 | base-excision repair, AP site formation (GO:0006285) | 2.97073968 |
| 60 | interaction with symbiont (GO:0051702) | 2.96369167 |
| 61 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.95770939 |
| 62 | lactate metabolic process (GO:0006089) | 2.91836724 |
| 63 | growth hormone secretion (GO:0030252) | 2.90930135 |
| 64 | histone H3-K36 demethylation (GO:0070544) | 2.89046158 |
| 65 | sterol biosynthetic process (GO:0016126) | 2.88404486 |
| 66 | DNA damage response, signal transduction resulting in transcription (GO:0042772) | 2.88272225 |
| 67 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 2.82816563 |
| 68 | histone H3 deacetylation (GO:0070932) | 2.80096390 |
| 69 | positive regulation of cell size (GO:0045793) | 2.79071256 |
| 70 | cell migration involved in sprouting angiogenesis (GO:0002042) | 2.77253621 |
| 71 | lung vasculature development (GO:0060426) | 2.74727789 |
| 72 | positive regulation of protein kinase C signaling (GO:0090037) | 2.73627439 |
| 73 | ER-nucleus signaling pathway (GO:0006984) | 2.72809031 |
| 74 | fibroblast migration (GO:0010761) | 2.71898350 |
| 75 | modulation of transcription in other organism involved in symbiotic interaction (GO:0052312) | 2.69851132 |
| 76 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.69560599 |
| 77 | maintenance of protein localization in organelle (GO:0072595) | 2.67940046 |
| 78 | negative regulation of gene silencing (GO:0060969) | 2.67479502 |
| 79 | GPI anchor biosynthetic process (GO:0006506) | 2.66758602 |
| 80 | myoblast differentiation (GO:0045445) | 2.66210148 |
| 81 | positive regulation of nuclease activity (GO:0032075) | 2.66072390 |
| 82 | endoplasmic reticulum unfolded protein response (GO:0030968) | 2.65168703 |
| 83 | monoubiquitinated protein deubiquitination (GO:0035520) | 2.61727373 |
| 84 | branching involved in prostate gland morphogenesis (GO:0060442) | 2.59750414 |
| 85 | regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139) | 2.58910287 |
| 86 | positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141) | 2.58910287 |
| 87 | mitotic chromosome condensation (GO:0007076) | 2.57158237 |
| 88 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.56746569 |
| 89 | ketone biosynthetic process (GO:0042181) | 2.54405847 |
| 90 | dolichol-linked oligosaccharide biosynthetic process (GO:0006488) | 2.53336740 |
| 91 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 2.49656078 |
| 92 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 2.49656078 |
| 93 | RNA-dependent DNA replication (GO:0006278) | 2.47331812 |
| 94 | cellular response to topologically incorrect protein (GO:0035967) | 2.46264059 |
| 95 | negative regulation of smooth muscle cell migration (GO:0014912) | 2.45644278 |
| 96 | cellular response to unfolded protein (GO:0034620) | 2.45591006 |
| 97 | regulation of cell migration involved in sprouting angiogenesis (GO:0090049) | 2.45184305 |
| 98 | C-terminal protein lipidation (GO:0006501) | 2.44939678 |
| 99 | positive regulation by host of viral transcription (GO:0043923) | 2.44449007 |
| 100 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.44284059 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 4.28322023 |
| 2 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 3.77270330 |
| 3 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.67216373 |
| 4 | MYC_22102868_ChIP-Seq_BL_Human | 2.66467120 |
| 5 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 2.48651152 |
| 6 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 2.40337647 |
| 7 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.35727340 |
| 8 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.30341748 |
| 9 | CIITA_25753668_ChIP-Seq_RAJI_Human | 2.24744113 |
| 10 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.23570327 |
| 11 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.16880130 |
| 12 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 2.15905652 |
| 13 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 2.15905652 |
| 14 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 2.15905652 |
| 15 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.09703601 |
| 16 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.05773179 |
| 17 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.88174880 |
| 18 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.87006581 |
| 19 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.77345165 |
| 20 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.74316333 |
| 21 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.73726029 |
| 22 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.72955211 |
| 23 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.72134279 |
| 24 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.69804731 |
| 25 | ATF3_27146783_Chip-Seq_COLON_Human | 1.65079534 |
| 26 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.63560308 |
| 27 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.63320709 |
| 28 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.62827905 |
| 29 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.58588649 |
| 30 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.57623112 |
| 31 | MAF_26560356_Chip-Seq_TH1_Human | 1.53549378 |
| 32 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.51618197 |
| 33 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.51324467 |
| 34 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.48789963 |
| 35 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.48462436 |
| 36 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.46930152 |
| 37 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.44677413 |
| 38 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.43817810 |
| 39 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.42704971 |
| 40 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.42507687 |
| 41 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.38284591 |
| 42 | MAF_26560356_Chip-Seq_TH2_Human | 1.37300461 |
| 43 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.35078003 |
| 44 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.33172964 |
| 45 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.33145496 |
| 46 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.32738690 |
| 47 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.31707443 |
| 48 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.30308821 |
| 49 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.28341181 |
| 50 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.26674354 |
| 51 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.26292083 |
| 52 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.25381704 |
| 53 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.24997355 |
| 54 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.24525392 |
| 55 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.24179993 |
| 56 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.23326685 |
| 57 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.23209357 |
| 58 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.22088893 |
| 59 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.20980683 |
| 60 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.20914764 |
| 61 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.19207907 |
| 62 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.18734759 |
| 63 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.18651033 |
| 64 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.18494951 |
| 65 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.17474993 |
| 66 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.16493570 |
| 67 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.16477041 |
| 68 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.16132100 |
| 69 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.15362612 |
| 70 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.14301261 |
| 71 | UTX_26944678_Chip-Seq_JUKART_Human | 1.13892079 |
| 72 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.12851195 |
| 73 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.12313727 |
| 74 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.12018826 |
| 75 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.11028323 |
| 76 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.10468162 |
| 77 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.09145808 |
| 78 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.08293751 |
| 79 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.07927409 |
| 80 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.07584260 |
| 81 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.06974820 |
| 82 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.06973721 |
| 83 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.05837480 |
| 84 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.03169445 |
| 85 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.99465438 |
| 86 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.99145854 |
| 87 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 0.99124280 |
| 88 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.98139555 |
| 89 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.97682661 |
| 90 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.97219068 |
| 91 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.96329892 |
| 92 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.95842023 |
| 93 | CTCF_21964334_Chip-Seq_Bcells_Human | 0.95827425 |
| 94 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.95448694 |
| 95 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.94731742 |
| 96 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 0.94455212 |
| 97 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.94371168 |
| 98 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.94127757 |
| 99 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.93916409 |
| 100 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 0.93119205 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008995_early_reproductive_senescence | 3.53672843 |
| 2 | MP0003950_abnormal_plasma_membrane | 3.40963337 |
| 3 | MP0003315_abnormal_perineum_morphology | 3.33274560 |
| 4 | MP0008260_abnormal_autophagy | 3.14215273 |
| 5 | MP0008789_abnormal_olfactory_epithelium | 2.84896145 |
| 6 | MP0008961_abnormal_basal_metabolism | 2.73912609 |
| 7 | MP0010234_abnormal_vibrissa_follicle | 2.63946010 |
| 8 | MP0002166_altered_tumor_susceptibility | 2.55825775 |
| 9 | MP0010030_abnormal_orbit_morphology | 2.55457666 |
| 10 | MP0005394_taste/olfaction_phenotype | 2.41552562 |
| 11 | MP0005499_abnormal_olfactory_system | 2.41552562 |
| 12 | MP0003941_abnormal_skin_development | 2.38460364 |
| 13 | MP0004272_abnormal_basement_membrane | 2.31057934 |
| 14 | MP0003656_abnormal_erythrocyte_physiolo | 2.27544190 |
| 15 | MP0003693_abnormal_embryo_hatching | 2.09431749 |
| 16 | MP0006054_spinal_hemorrhage | 2.09366074 |
| 17 | MP0003279_aneurysm | 2.00285162 |
| 18 | MP0005645_abnormal_hypothalamus_physiol | 2.00065327 |
| 19 | MP0003172_abnormal_lysosome_physiology | 1.99735019 |
| 20 | MP0000537_abnormal_urethra_morphology | 1.97732834 |
| 21 | MP0005410_abnormal_fertilization | 1.92354674 |
| 22 | MP0008438_abnormal_cutaneous_collagen | 1.83283045 |
| 23 | MP0005076_abnormal_cell_differentiation | 1.76356079 |
| 24 | MP0006292_abnormal_olfactory_placode | 1.71280138 |
| 25 | MP0006072_abnormal_retinal_apoptosis | 1.71007032 |
| 26 | MP0003077_abnormal_cell_cycle | 1.67413652 |
| 27 | MP0003091_abnormal_cell_migration | 1.66330065 |
| 28 | MP0003221_abnormal_cardiomyocyte_apopto | 1.64780639 |
| 29 | MP0010094_abnormal_chromosome_stability | 1.63775113 |
| 30 | MP0009697_abnormal_copulation | 1.63587201 |
| 31 | MP0008058_abnormal_DNA_repair | 1.60858921 |
| 32 | MP0005647_abnormal_sex_gland | 1.60245778 |
| 33 | MP0002160_abnormal_reproductive_system | 1.59845158 |
| 34 | MP0004043_abnormal_pH_regulation | 1.59736701 |
| 35 | MP0003111_abnormal_nucleus_morphology | 1.50962412 |
| 36 | MP0004233_abnormal_muscle_weight | 1.49451839 |
| 37 | MP0003786_premature_aging | 1.46495225 |
| 38 | MP0002006_tumorigenesis | 1.41999074 |
| 39 | MP0000358_abnormal_cell_content/ | 1.37447129 |
| 40 | MP0002009_preneoplasia | 1.32029538 |
| 41 | MP0001545_abnormal_hematopoietic_system | 1.27933731 |
| 42 | MP0005397_hematopoietic_system_phenotyp | 1.27933731 |
| 43 | MP0005083_abnormal_biliary_tract | 1.27362478 |
| 44 | MP0008932_abnormal_embryonic_tissue | 1.23562806 |
| 45 | MP0003183_abnormal_peptide_metabolism | 1.18824803 |
| 46 | MP0003755_abnormal_palate_morphology | 1.17397415 |
| 47 | MP0001270_distended_abdomen | 1.17059084 |
| 48 | MP0001119_abnormal_female_reproductive | 1.11686372 |
| 49 | MP0000678_abnormal_parathyroid_gland | 1.11651717 |
| 50 | MP0000733_abnormal_muscle_development | 1.11288439 |
| 51 | MP0003191_abnormal_cellular_cholesterol | 1.10498713 |
| 52 | MP0003195_calcinosis | 1.08863279 |
| 53 | MP0001727_abnormal_embryo_implantation | 1.08513163 |
| 54 | MP0000350_abnormal_cell_proliferation | 1.06213811 |
| 55 | MP0006035_abnormal_mitochondrial_morpho | 1.03808549 |
| 56 | MP0002254_reproductive_system_inflammat | 0.96743385 |
| 57 | MP0005389_reproductive_system_phenotype | 0.96091482 |
| 58 | MP0002111_abnormal_tail_morphology | 0.95232585 |
| 59 | MP0003942_abnormal_urinary_system | 0.92561406 |
| 60 | MP0005310_abnormal_salivary_gland | 0.92216584 |
| 61 | MP0001853_heart_inflammation | 0.92156868 |
| 62 | MP0002735_abnormal_chemical_nociception | 0.90796750 |
| 63 | MP0002877_abnormal_melanocyte_morpholog | 0.87769347 |
| 64 | MP0004742_abnormal_vestibular_system | 0.87296875 |
| 65 | MP0004510_myositis | 0.86919566 |
| 66 | MP0005377_hearing/vestibular/ear_phenot | 0.84677817 |
| 67 | MP0003878_abnormal_ear_physiology | 0.84677817 |
| 68 | MP0004147_increased_porphyrin_level | 0.84199976 |
| 69 | MP0005621_abnormal_cell_physiology | 0.82109763 |
| 70 | MP0003115_abnormal_respiratory_system | 0.79717646 |
| 71 | MP0005384_cellular_phenotype | 0.79066566 |
| 72 | MP0005023_abnormal_wound_healing | 0.78971241 |
| 73 | MP0001529_abnormal_vocalization | 0.77973671 |
| 74 | MP0000163_abnormal_cartilage_morphology | 0.77701005 |
| 75 | MP0009278_abnormal_bone_marrow | 0.76391349 |
| 76 | MP0002653_abnormal_ependyma_morphology | 0.76302634 |
| 77 | MP0000313_abnormal_cell_death | 0.75657743 |
| 78 | MP0002295_abnormal_pulmonary_circulatio | 0.74610025 |
| 79 | MP0009333_abnormal_splenocyte_physiolog | 0.73960496 |
| 80 | MP0005187_abnormal_penis_morphology | 0.73754645 |
| 81 | MP0003699_abnormal_female_reproductive | 0.71968268 |
| 82 | MP0005501_abnormal_skin_physiology | 0.70526143 |
| 83 | MP0000432_abnormal_head_morphology | 0.70051502 |
| 84 | MP0000613_abnormal_salivary_gland | 0.69944401 |
| 85 | MP0002405_respiratory_system_inflammati | 0.69014119 |
| 86 | MP0002722_abnormal_immune_system | 0.68830366 |
| 87 | MP0000653_abnormal_sex_gland | 0.68716934 |
| 88 | MP0008004_abnormal_stomach_pH | 0.68233403 |
| 89 | MP0010678_abnormal_skin_adnexa | 0.67416955 |
| 90 | MP0003632_abnormal_nervous_system | 0.67271172 |
| 91 | MP0003186_abnormal_redox_activity | 0.66908857 |
| 92 | MP0005167_abnormal_blood-brain_barrier | 0.66443296 |
| 93 | MP0003984_embryonic_growth_retardation | 0.66128587 |
| 94 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.66118651 |
| 95 | MP0010307_abnormal_tumor_latency | 0.64691777 |
| 96 | MP0002080_prenatal_lethality | 0.64421166 |
| 97 | MP0002396_abnormal_hematopoietic_system | 0.63638863 |
| 98 | MP0002084_abnormal_developmental_patter | 0.62409560 |
| 99 | MP0008007_abnormal_cellular_replicative | 0.61483616 |
| 100 | MP0003385_abnormal_body_wall | 0.61377683 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Natal tooth (HP:0000695) | 4.58838788 |
| 2 | Cervical subluxation (HP:0003308) | 4.04784048 |
| 3 | Diplopia (HP:0000651) | 4.03085568 |
| 4 | Abnormality of binocular vision (HP:0011514) | 4.03085568 |
| 5 | Long palpebral fissure (HP:0000637) | 3.60826146 |
| 6 | Increased serum ferritin (HP:0003281) | 3.43784099 |
| 7 | Progressive muscle weakness (HP:0003323) | 3.36913051 |
| 8 | Increased serum pyruvate (HP:0003542) | 3.35518002 |
| 9 | Trigonocephaly (HP:0000243) | 3.23685026 |
| 10 | Neonatal short-limb short stature (HP:0008921) | 3.20306527 |
| 11 | Paralysis (HP:0003470) | 3.07058337 |
| 12 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 2.98810747 |
| 13 | Recurrent sinusitis (HP:0011108) | 2.91969245 |
| 14 | Abnormality of glycolysis (HP:0004366) | 2.87204966 |
| 15 | Increased cerebral lipofuscin (HP:0011813) | 2.87038079 |
| 16 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.83913962 |
| 17 | Male infertility (HP:0003251) | 2.72850744 |
| 18 | Long eyelashes (HP:0000527) | 2.71643992 |
| 19 | Reticulocytosis (HP:0001923) | 2.70935558 |
| 20 | Urethral obstruction (HP:0000796) | 2.66129304 |
| 21 | Sparse lateral eyebrow (HP:0005338) | 2.57941236 |
| 22 | High anterior hairline (HP:0009890) | 2.49932968 |
| 23 | Abnormality of the pons (HP:0007361) | 2.44667570 |
| 24 | Spinal cord lesions (HP:0100561) | 2.43360939 |
| 25 | Syringomyelia (HP:0003396) | 2.43360939 |
| 26 | Microvesicular hepatic steatosis (HP:0001414) | 2.41086411 |
| 27 | Ectopic kidney (HP:0000086) | 2.41038122 |
| 28 | Cupped ribs (HP:0000887) | 2.40049576 |
| 29 | Short 5th finger (HP:0009237) | 2.39332775 |
| 30 | Exercise-induced muscle cramps (HP:0003710) | 2.38633538 |
| 31 | Short humerus (HP:0005792) | 2.38083184 |
| 32 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.36348896 |
| 33 | Depressed nasal tip (HP:0000437) | 2.35024102 |
| 34 | Hyperglycinemia (HP:0002154) | 2.30724056 |
| 35 | Abnormality of the alveolar ridges (HP:0006477) | 2.30706124 |
| 36 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.29270909 |
| 37 | Septo-optic dysplasia (HP:0100842) | 2.27091981 |
| 38 | Spastic paraplegia (HP:0001258) | 2.26833336 |
| 39 | Genetic anticipation (HP:0003743) | 2.26623168 |
| 40 | Aplasia/hypoplasia of the humerus (HP:0006507) | 2.24949565 |
| 41 | Lip pit (HP:0100267) | 2.21774647 |
| 42 | Flat acetabular roof (HP:0003180) | 2.20413764 |
| 43 | Abnormal biliary tract physiology (HP:0012439) | 2.19723255 |
| 44 | Bile duct proliferation (HP:0001408) | 2.19723255 |
| 45 | Abnormality of the columella (HP:0009929) | 2.17657290 |
| 46 | Confusion (HP:0001289) | 2.14585248 |
| 47 | Advanced eruption of teeth (HP:0006288) | 2.14411206 |
| 48 | Abnormality of iron homeostasis (HP:0011031) | 2.13566421 |
| 49 | Hypercholesterolemia (HP:0003124) | 2.03185126 |
| 50 | Homocystinuria (HP:0002156) | 2.00038809 |
| 51 | Abnormality of homocysteine metabolism (HP:0010919) | 2.00038809 |
| 52 | Hemorrhage of the eye (HP:0011885) | 1.99460493 |
| 53 | Postnatal microcephaly (HP:0005484) | 1.98791849 |
| 54 | Autoimmune thrombocytopenia (HP:0001973) | 1.96791413 |
| 55 | Aplasia/Hypoplasia of the 5th finger (HP:0006262) | 1.96251105 |
| 56 | Asplenia (HP:0001746) | 1.95234217 |
| 57 | Poor head control (HP:0002421) | 1.94990388 |
| 58 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.94229371 |
| 59 | Facial cleft (HP:0002006) | 1.93577806 |
| 60 | Thoracic kyphosis (HP:0002942) | 1.92311269 |
| 61 | Hyperacusis (HP:0010780) | 1.91569231 |
| 62 | Mitral stenosis (HP:0001718) | 1.91196535 |
| 63 | Abnormality of glycolipid metabolism (HP:0010969) | 1.88335243 |
| 64 | Abnormality of liposaccharide metabolism (HP:0010968) | 1.88335243 |
| 65 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 1.88335243 |
| 66 | Capillary hemangiomas (HP:0005306) | 1.87668716 |
| 67 | Vacuolated lymphocytes (HP:0001922) | 1.87295187 |
| 68 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.85088470 |
| 69 | Abnormality of carpal bone ossification (HP:0006257) | 1.84782443 |
| 70 | Diminished motivation (HP:0000745) | 1.84612475 |
| 71 | Broad thumb (HP:0011304) | 1.82762267 |
| 72 | Paraplegia (HP:0010550) | 1.81651968 |
| 73 | Gonadotropin excess (HP:0000837) | 1.80605455 |
| 74 | Hypoplasia of the pons (HP:0012110) | 1.80290167 |
| 75 | Reduced antithrombin III activity (HP:0001976) | 1.80272078 |
| 76 | Abnormality of the thoracic spine (HP:0100711) | 1.79804417 |
| 77 | Back pain (HP:0003418) | 1.79328816 |
| 78 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.77625175 |
| 79 | Diastasis recti (HP:0001540) | 1.76332426 |
| 80 | Hepatocellular carcinoma (HP:0001402) | 1.76076148 |
| 81 | Abnormality of the lower motor neuron (HP:0002366) | 1.75899561 |
| 82 | Flared iliac wings (HP:0002869) | 1.75445120 |
| 83 | Supernumerary spleens (HP:0009799) | 1.74654583 |
| 84 | Dyschromatopsia (HP:0007641) | 1.71747772 |
| 85 | Interstitial pulmonary disease (HP:0006530) | 1.71621008 |
| 86 | Hypoplasia of the odontoid process (HP:0003311) | 1.71333496 |
| 87 | Upper limb muscle weakness (HP:0003484) | 1.71061322 |
| 88 | Abnormality of reticulocytes (HP:0004312) | 1.70918140 |
| 89 | Morphological abnormality of the middle ear (HP:0008609) | 1.70269071 |
| 90 | Abnormal ossification of hand bones (HP:0005921) | 1.69939659 |
| 91 | Broad alveolar ridges (HP:0000187) | 1.69047142 |
| 92 | Abnormal number of erythroid precursors (HP:0012131) | 1.68811452 |
| 93 | Abnormality of the nasal septum (HP:0000419) | 1.66865174 |
| 94 | Arthropathy (HP:0003040) | 1.65190919 |
| 95 | Recurrent otitis media (HP:0000403) | 1.64246460 |
| 96 | Retinal dysplasia (HP:0007973) | 1.63377798 |
| 97 | Mask-like facies (HP:0000298) | 1.63182549 |
| 98 | Abnormality of abdominal situs (HP:0011620) | 1.63122145 |
| 99 | Abdominal situs inversus (HP:0003363) | 1.63122145 |
| 100 | Dyskinesia (HP:0100660) | 1.62523519 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CDK12 | 4.20096910 |
| 2 | MAP4K2 | 3.92090058 |
| 3 | DDR2 | 3.80886952 |
| 4 | BRSK2 | 3.25649058 |
| 5 | TRIM28 | 3.13383338 |
| 6 | MAP3K13 | 2.85285271 |
| 7 | ICK | 2.82632878 |
| 8 | SRPK1 | 2.82471397 |
| 9 | MAP3K7 | 2.54507365 |
| 10 | SMG1 | 2.37017350 |
| 11 | CAMK1D | 2.26506091 |
| 12 | MAP3K3 | 2.25450109 |
| 13 | CSNK1A1L | 2.15233412 |
| 14 | EPHA2 | 2.09803254 |
| 15 | CDC7 | 1.91119586 |
| 16 | MAPK11 | 1.70801699 |
| 17 | CSNK1G3 | 1.68593117 |
| 18 | CAMK1G | 1.49775624 |
| 19 | PAK4 | 1.34010131 |
| 20 | PKN2 | 1.31562802 |
| 21 | BRSK1 | 1.29982250 |
| 22 | VRK2 | 1.28453723 |
| 23 | MST1R | 1.28052017 |
| 24 | WEE1 | 1.27846439 |
| 25 | IRAK3 | 1.27316228 |
| 26 | CDK19 | 1.26842161 |
| 27 | RIPK4 | 1.25902440 |
| 28 | CDK6 | 1.23302704 |
| 29 | MOS | 1.21652798 |
| 30 | WNK4 | 1.19581497 |
| 31 | BMPR2 | 1.15670936 |
| 32 | SIK3 | 1.12066316 |
| 33 | MAP3K14 | 1.09726943 |
| 34 | ARAF | 1.09546463 |
| 35 | CCNB1 | 1.06996574 |
| 36 | CSNK1G1 | 1.04868145 |
| 37 | FLT3 | 0.97865950 |
| 38 | MTOR | 0.95838644 |
| 39 | CSNK1G2 | 0.94300391 |
| 40 | CDK4 | 0.90122522 |
| 41 | ERN1 | 0.89063362 |
| 42 | LMTK2 | 0.87063677 |
| 43 | CHEK1 | 0.86989355 |
| 44 | VRK1 | 0.86942305 |
| 45 | BRD4 | 0.85510375 |
| 46 | SIK1 | 0.84023361 |
| 47 | PRKAA1 | 0.82240951 |
| 48 | FGFR1 | 0.82227123 |
| 49 | PKN1 | 0.82071631 |
| 50 | NEK9 | 0.80636882 |
| 51 | MAP3K11 | 0.79754311 |
| 52 | GRK1 | 0.78302305 |
| 53 | TRIB3 | 0.75028788 |
| 54 | ATR | 0.73290438 |
| 55 | DYRK1B | 0.72123207 |
| 56 | MATK | 0.70929861 |
| 57 | BTK | 0.68525265 |
| 58 | FES | 0.67849556 |
| 59 | CDK7 | 0.65706942 |
| 60 | RPS6KA4 | 0.63985417 |
| 61 | ERBB4 | 0.61997504 |
| 62 | NEK2 | 0.57594492 |
| 63 | EPHA4 | 0.55697405 |
| 64 | STK10 | 0.55609336 |
| 65 | PIM2 | 0.53578972 |
| 66 | RPS6KC1 | 0.53182868 |
| 67 | RPS6KL1 | 0.53182868 |
| 68 | KSR2 | 0.52516227 |
| 69 | TYK2 | 0.51907244 |
| 70 | DAPK1 | 0.50623170 |
| 71 | PLK1 | 0.49943517 |
| 72 | TBK1 | 0.49557504 |
| 73 | PRKD2 | 0.49006575 |
| 74 | GSK3A | 0.48146048 |
| 75 | ATM | 0.47884909 |
| 76 | HCK | 0.47833506 |
| 77 | MARK2 | 0.47657795 |
| 78 | SIK2 | 0.47036068 |
| 79 | PRKAA2 | 0.46771464 |
| 80 | RPS6KA6 | 0.43392915 |
| 81 | CDC42BPA | 0.43049290 |
| 82 | CSNK1A1 | 0.42705156 |
| 83 | CDK9 | 0.41241071 |
| 84 | DYRK3 | 0.40406276 |
| 85 | IKBKB | 0.39808623 |
| 86 | MAP3K9 | 0.39128748 |
| 87 | SCYL2 | 0.38887372 |
| 88 | MAP2K3 | 0.38476296 |
| 89 | ZAK | 0.37893231 |
| 90 | CHEK2 | 0.37195602 |
| 91 | IRAK4 | 0.36992368 |
| 92 | KIT | 0.35976373 |
| 93 | AKT1 | 0.35515057 |
| 94 | CDK2 | 0.35150727 |
| 95 | TEC | 0.34632824 |
| 96 | TLK1 | 0.34534498 |
| 97 | PRKD1 | 0.33132418 |
| 98 | CHUK | 0.33028455 |
| 99 | DYRK1A | 0.32430005 |
| 100 | ERBB3 | 0.32387066 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 3.73407653 |
| 2 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 3.33483402 |
| 3 | Base excision repair_Homo sapiens_hsa03410 | 3.19512601 |
| 4 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 3.16101691 |
| 5 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.59636815 |
| 6 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 2.56583299 |
| 7 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.48735188 |
| 8 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 2.39313745 |
| 9 | DNA replication_Homo sapiens_hsa03030 | 2.12374890 |
| 10 | Lysine degradation_Homo sapiens_hsa00310 | 2.09991912 |
| 11 | Other glycan degradation_Homo sapiens_hsa00511 | 2.04691378 |
| 12 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.83367166 |
| 13 | Prostate cancer_Homo sapiens_hsa05215 | 1.76326085 |
| 14 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.74802594 |
| 15 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.72016963 |
| 16 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.61913928 |
| 17 | Spliceosome_Homo sapiens_hsa03040 | 1.56576996 |
| 18 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.49534757 |
| 19 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.46644460 |
| 20 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.41970208 |
| 21 | Homologous recombination_Homo sapiens_hsa03440 | 1.35967911 |
| 22 | Bladder cancer_Homo sapiens_hsa05219 | 1.31451303 |
| 23 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 1.27288161 |
| 24 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.24728810 |
| 25 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.21335096 |
| 26 | Thyroid cancer_Homo sapiens_hsa05216 | 1.15353818 |
| 27 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.14287569 |
| 28 | Mineral absorption_Homo sapiens_hsa04978 | 1.12815644 |
| 29 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 1.10974785 |
| 30 | Shigellosis_Homo sapiens_hsa05131 | 1.09426272 |
| 31 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.06742406 |
| 32 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.06166983 |
| 33 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.04313910 |
| 34 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.03856199 |
| 35 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.01445171 |
| 36 | Hepatitis B_Homo sapiens_hsa05161 | 1.00885058 |
| 37 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.00459687 |
| 38 | Galactose metabolism_Homo sapiens_hsa00052 | 0.96749981 |
| 39 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.94088570 |
| 40 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.93962985 |
| 41 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.92609171 |
| 42 | RNA transport_Homo sapiens_hsa03013 | 0.92569017 |
| 43 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.90007337 |
| 44 | Insulin resistance_Homo sapiens_hsa04931 | 0.89424505 |
| 45 | Cell cycle_Homo sapiens_hsa04110 | 0.88665286 |
| 46 | RNA polymerase_Homo sapiens_hsa03020 | 0.87869075 |
| 47 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.86222196 |
| 48 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.84693599 |
| 49 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.83815838 |
| 50 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.83273649 |
| 51 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.81215523 |
| 52 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.80131410 |
| 53 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.75769917 |
| 54 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.73403705 |
| 55 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.71352414 |
| 56 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.70457924 |
| 57 | Influenza A_Homo sapiens_hsa05164 | 0.65148551 |
| 58 | Circadian rhythm_Homo sapiens_hsa04710 | 0.65052568 |
| 59 | Adherens junction_Homo sapiens_hsa04520 | 0.64259069 |
| 60 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.62379115 |
| 61 | HTLV-I infection_Homo sapiens_hsa05166 | 0.62006907 |
| 62 | Lysosome_Homo sapiens_hsa04142 | 0.61016432 |
| 63 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.59884112 |
| 64 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.59542465 |
| 65 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.56474089 |
| 66 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.56420917 |
| 67 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.56233777 |
| 68 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.54213478 |
| 69 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.53802039 |
| 70 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.53236477 |
| 71 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.53112042 |
| 72 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.52984525 |
| 73 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.52912808 |
| 74 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.52594098 |
| 75 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.52527367 |
| 76 | Legionellosis_Homo sapiens_hsa05134 | 0.50031517 |
| 77 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.50023662 |
| 78 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.49589547 |
| 79 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.49170483 |
| 80 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.49084782 |
| 81 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.46582519 |
| 82 | Endometrial cancer_Homo sapiens_hsa05213 | 0.45944172 |
| 83 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.45730365 |
| 84 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.44031734 |
| 85 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.43800430 |
| 86 | Measles_Homo sapiens_hsa05162 | 0.42946658 |
| 87 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.42858564 |
| 88 | Apoptosis_Homo sapiens_hsa04210 | 0.42421919 |
| 89 | Viral myocarditis_Homo sapiens_hsa05416 | 0.39288575 |
| 90 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.38592728 |
| 91 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.38080044 |
| 92 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.38010269 |
| 93 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.37353505 |
| 94 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.35594872 |
| 95 | Protein export_Homo sapiens_hsa03060 | 0.35374540 |
| 96 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.34666202 |
| 97 | Asthma_Homo sapiens_hsa05310 | 0.34154094 |
| 98 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.33842013 |
| 99 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.33596679 |
| 100 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.33371800 |

