

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | cytidine deamination (GO:0009972) | 8.42620251 |
| 2 | cytidine metabolic process (GO:0046087) | 8.42620251 |
| 3 | cytidine catabolic process (GO:0006216) | 8.42620251 |
| 4 | DNA deamination (GO:0045006) | 8.31800694 |
| 5 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 8.04799193 |
| 6 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 7.28895820 |
| 7 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.81647355 |
| 8 | ATP synthesis coupled proton transport (GO:0015986) | 4.57430473 |
| 9 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.57430473 |
| 10 | protein neddylation (GO:0045116) | 4.37224493 |
| 11 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.16491766 |
| 12 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.84947261 |
| 13 | respiratory electron transport chain (GO:0022904) | 3.82850844 |
| 14 | electron transport chain (GO:0022900) | 3.80267132 |
| 15 | pyrimidine nucleoside catabolic process (GO:0046135) | 3.78491832 |
| 16 | actin nucleation (GO:0045010) | 3.74978854 |
| 17 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.72786454 |
| 18 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.69506984 |
| 19 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.63534899 |
| 20 | negative regulation by host of viral transcription (GO:0043922) | 3.61487096 |
| 21 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.59173501 |
| 22 | sequestering of actin monomers (GO:0042989) | 3.58239302 |
| 23 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.53502907 |
| 24 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.53502907 |
| 25 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.53502907 |
| 26 | ribosomal small subunit assembly (GO:0000028) | 3.52560218 |
| 27 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.51691386 |
| 28 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.51691386 |
| 29 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.44350096 |
| 30 | negative regulation of ligase activity (GO:0051352) | 3.40112121 |
| 31 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.40112121 |
| 32 | protein complex biogenesis (GO:0070271) | 3.35161627 |
| 33 | positive regulation of interleukin-8 secretion (GO:2000484) | 3.34518091 |
| 34 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.34214232 |
| 35 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.34214232 |
| 36 | chaperone-mediated protein transport (GO:0072321) | 3.34103801 |
| 37 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.31471891 |
| 38 | negative regulation of T cell apoptotic process (GO:0070233) | 3.28025106 |
| 39 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.27356425 |
| 40 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.25717596 |
| 41 | positive T cell selection (GO:0043368) | 3.25050785 |
| 42 | proteasome assembly (GO:0043248) | 3.23563263 |
| 43 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.23282970 |
| 44 | regulation of chronic inflammatory response (GO:0002676) | 3.21302180 |
| 45 | DNA demethylation (GO:0080111) | 3.18559982 |
| 46 | positive thymic T cell selection (GO:0045059) | 3.18019206 |
| 47 | metallo-sulfur cluster assembly (GO:0031163) | 3.16111632 |
| 48 | iron-sulfur cluster assembly (GO:0016226) | 3.16111632 |
| 49 | negative regulation of viral genome replication (GO:0045071) | 3.15155233 |
| 50 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.11733416 |
| 51 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.04044041 |
| 52 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.02676652 |
| 53 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.02107596 |
| 54 | termination of RNA polymerase III transcription (GO:0006386) | 3.02107596 |
| 55 | positive regulation of B cell differentiation (GO:0045579) | 3.00963011 |
| 56 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.98050085 |
| 57 | behavioral response to nicotine (GO:0035095) | 2.97985206 |
| 58 | positive regulation of defense response to virus by host (GO:0002230) | 2.97189091 |
| 59 | NADH dehydrogenase complex assembly (GO:0010257) | 2.95864892 |
| 60 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.95864892 |
| 61 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.95864892 |
| 62 | regulation of activation of Janus kinase activity (GO:0010533) | 2.93289913 |
| 63 | pyrimidine-containing compound catabolic process (GO:0072529) | 2.92365370 |
| 64 | positive regulation of calcium-mediated signaling (GO:0050850) | 2.92188256 |
| 65 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.91657463 |
| 66 | DNA dealkylation (GO:0035510) | 2.88970830 |
| 67 | negative T cell selection (GO:0043383) | 2.86533138 |
| 68 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.86529817 |
| 69 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.84594990 |
| 70 | positive regulation of cell cycle arrest (GO:0071158) | 2.83853718 |
| 71 | rRNA modification (GO:0000154) | 2.78181804 |
| 72 | positive regulation of ligase activity (GO:0051351) | 2.76943692 |
| 73 | cytolysis (GO:0019835) | 2.75748865 |
| 74 | cytochrome complex assembly (GO:0017004) | 2.75680458 |
| 75 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 2.75023084 |
| 76 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.73728064 |
| 77 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.73728064 |
| 78 | protein-cofactor linkage (GO:0018065) | 2.73379747 |
| 79 | regulation of cellular amine metabolic process (GO:0033238) | 2.72960376 |
| 80 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 2.72682235 |
| 81 | regulation of regulatory T cell differentiation (GO:0045589) | 2.72587845 |
| 82 | pyrimidine ribonucleoside metabolic process (GO:0046131) | 2.71758715 |
| 83 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.71027285 |
| 84 | platelet dense granule organization (GO:0060155) | 2.69345379 |
| 85 | regulation of interleukin-8 secretion (GO:2000482) | 2.69087098 |
| 86 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.68532662 |
| 87 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.67194634 |
| 88 | hydrogen ion transmembrane transport (GO:1902600) | 2.66814751 |
| 89 | cellular response to interleukin-15 (GO:0071350) | 2.66318394 |
| 90 | T cell migration (GO:0072678) | 2.66154710 |
| 91 | response to interferon-beta (GO:0035456) | 2.64390400 |
| 92 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 2.64149761 |
| 93 | eosinophil chemotaxis (GO:0048245) | 2.63770654 |
| 94 | respiratory chain complex IV assembly (GO:0008535) | 2.62777923 |
| 95 | macrophage chemotaxis (GO:0048246) | 2.61966493 |
| 96 | proton transport (GO:0015992) | 2.59746159 |
| 97 | negative regulation of telomere maintenance (GO:0032205) | 2.56717547 |
| 98 | mannosylation (GO:0097502) | 2.56537678 |
| 99 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.56093362 |
| 100 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.56029403 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.60760058 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.11698283 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.84295751 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.39376734 |
| 5 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.38481058 |
| 6 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.23484279 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.02110505 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.83425835 |
| 9 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.76994355 |
| 10 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.70556541 |
| 11 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.64069283 |
| 12 | VDR_22108803_ChIP-Seq_LS180_Human | 2.60051206 |
| 13 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.48606981 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.45733810 |
| 15 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.42923417 |
| 16 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.35879914 |
| 17 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.30683330 |
| 18 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.22442085 |
| 19 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.18415931 |
| 20 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.10291018 |
| 21 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.03223973 |
| 22 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.01014539 |
| 23 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.98859773 |
| 24 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.91910072 |
| 25 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.89576007 |
| 26 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.73550053 |
| 27 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.71021885 |
| 28 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.65500623 |
| 29 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.63294468 |
| 30 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.59700796 |
| 31 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.57503755 |
| 32 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.53558019 |
| 33 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.51565657 |
| 34 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.50811169 |
| 35 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.50605228 |
| 36 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.49299300 |
| 37 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.47337013 |
| 38 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.43435758 |
| 39 | MYB_26560356_Chip-Seq_TH2_Human | 1.42167835 |
| 40 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.41039275 |
| 41 | GATA3_26560356_Chip-Seq_TH2_Human | 1.36128435 |
| 42 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.35656471 |
| 43 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.33920157 |
| 44 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.30203069 |
| 45 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.28350369 |
| 46 | AR_20517297_ChIP-Seq_VCAP_Human | 1.27013085 |
| 47 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.24245266 |
| 48 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.23539341 |
| 49 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.22215574 |
| 50 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.22118476 |
| 51 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.21120445 |
| 52 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.21120445 |
| 53 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.19675559 |
| 54 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.19537570 |
| 55 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.18479891 |
| 56 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.16425444 |
| 57 | EWS_26573619_Chip-Seq_HEK293_Human | 1.16353718 |
| 58 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.16110926 |
| 59 | NCOR_22424771_ChIP-Seq_293T_Human | 1.15565386 |
| 60 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.15138243 |
| 61 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.14350415 |
| 62 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.14119888 |
| 63 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.13192624 |
| 64 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.13098369 |
| 65 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.12992107 |
| 66 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.11649063 |
| 67 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.11310493 |
| 68 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.09961108 |
| 69 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.07987911 |
| 70 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.07766788 |
| 71 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.06138670 |
| 72 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.06138670 |
| 73 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.05682229 |
| 74 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.05625290 |
| 75 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.04739772 |
| 76 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.04455393 |
| 77 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.03619696 |
| 78 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.03341544 |
| 79 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.01303152 |
| 80 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.00922480 |
| 81 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.00830617 |
| 82 | ERA_21632823_ChIP-Seq_H3396_Human | 1.00651222 |
| 83 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.99963362 |
| 84 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.98040884 |
| 85 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.95966953 |
| 86 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.95184996 |
| 87 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.93784773 |
| 88 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.93597174 |
| 89 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.92887239 |
| 90 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.91886956 |
| 91 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.91781039 |
| 92 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.91570808 |
| 93 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.91565985 |
| 94 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.90768120 |
| 95 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.90600390 |
| 96 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.90539884 |
| 97 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.88402623 |
| 98 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.88189936 |
| 99 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.87693450 |
| 100 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.87386013 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.91501896 |
| 2 | MP0001873_stomach_inflammation | 2.83093774 |
| 3 | MP0004147_increased_porphyrin_level | 2.70571832 |
| 4 | MP0001835_abnormal_antigen_presentation | 2.65587752 |
| 5 | MP0003763_abnormal_thymus_physiology | 2.32556311 |
| 6 | MP0002102_abnormal_ear_morphology | 2.30142513 |
| 7 | MP0009785_altered_susceptibility_to | 2.25274793 |
| 8 | MP0008877_abnormal_DNA_methylation | 2.23247616 |
| 9 | MP0009333_abnormal_splenocyte_physiolog | 2.08359658 |
| 10 | MP0008875_abnormal_xenobiotic_pharmacok | 2.06705082 |
| 11 | MP0008872_abnormal_physiological_respon | 1.97628507 |
| 12 | MP0006072_abnormal_retinal_apoptosis | 1.93260615 |
| 13 | MP0002876_abnormal_thyroid_physiology | 1.92721801 |
| 14 | MP0002148_abnormal_hypersensitivity_rea | 1.90644596 |
| 15 | MP0002138_abnormal_hepatobiliary_system | 1.87469918 |
| 16 | MP0003786_premature_aging | 1.84676906 |
| 17 | MP0001800_abnormal_humoral_immune | 1.84393931 |
| 18 | MP0003011_delayed_dark_adaptation | 1.82724801 |
| 19 | MP0006292_abnormal_olfactory_placode | 1.80477979 |
| 20 | MP0002277_abnormal_respiratory_mucosa | 1.78359317 |
| 21 | MP0002166_altered_tumor_susceptibility | 1.75826442 |
| 22 | MP0005645_abnormal_hypothalamus_physiol | 1.75500900 |
| 23 | MP0005000_abnormal_immune_tolerance | 1.69066713 |
| 24 | MP0000685_abnormal_immune_system | 1.65785655 |
| 25 | MP0001919_abnormal_reproductive_system | 1.63241427 |
| 26 | MP0000372_irregular_coat_pigmentation | 1.62136826 |
| 27 | MP0001905_abnormal_dopamine_level | 1.57594086 |
| 28 | MP0002420_abnormal_adaptive_immunity | 1.57333118 |
| 29 | MP0003806_abnormal_nucleotide_metabolis | 1.55966723 |
| 30 | MP0005551_abnormal_eye_electrophysiolog | 1.54159301 |
| 31 | MP0002723_abnormal_immune_serum | 1.52933640 |
| 32 | MP0005646_abnormal_pituitary_gland | 1.52350259 |
| 33 | MP0003646_muscle_fatigue | 1.52300547 |
| 34 | MP0009379_abnormal_foot_pigmentation | 1.52253487 |
| 35 | MP0001819_abnormal_immune_cell | 1.51412032 |
| 36 | MP0002736_abnormal_nociception_after | 1.51334080 |
| 37 | MP0002006_tumorigenesis | 1.51000106 |
| 38 | MP0001485_abnormal_pinna_reflex | 1.49383074 |
| 39 | MP0005025_abnormal_response_to | 1.46499653 |
| 40 | MP0001968_abnormal_touch/_nociception | 1.42758052 |
| 41 | MP0003866_abnormal_defecation | 1.42502635 |
| 42 | MP0005387_immune_system_phenotype | 1.41882410 |
| 43 | MP0001790_abnormal_immune_system | 1.41882410 |
| 44 | MP0005389_reproductive_system_phenotype | 1.41517495 |
| 45 | MP0003787_abnormal_imprinting | 1.39546613 |
| 46 | MP0008995_early_reproductive_senescence | 1.37666507 |
| 47 | MP0003878_abnormal_ear_physiology | 1.37147623 |
| 48 | MP0005377_hearing/vestibular/ear_phenot | 1.37147623 |
| 49 | MP0005253_abnormal_eye_physiology | 1.33619939 |
| 50 | MP0005084_abnormal_gallbladder_morpholo | 1.31694084 |
| 51 | MP0002452_abnormal_antigen_presenting | 1.30548964 |
| 52 | MP0006082_CNS_inflammation | 1.27509515 |
| 53 | MP0004145_abnormal_muscle_electrophysio | 1.26634550 |
| 54 | MP0006036_abnormal_mitochondrial_physio | 1.26352776 |
| 55 | MP0002398_abnormal_bone_marrow | 1.21601115 |
| 56 | MP0000716_abnormal_immune_system | 1.20381690 |
| 57 | MP0001986_abnormal_taste_sensitivity | 1.19014124 |
| 58 | MP0005410_abnormal_fertilization | 1.18338860 |
| 59 | MP0000689_abnormal_spleen_morphology | 1.11232337 |
| 60 | MP0003693_abnormal_embryo_hatching | 1.11232091 |
| 61 | MP0003195_calcinosis | 1.11217282 |
| 62 | MP0002095_abnormal_skin_pigmentation | 1.09121139 |
| 63 | MP0002163_abnormal_gland_morphology | 1.08716191 |
| 64 | MP0008058_abnormal_DNA_repair | 1.07320879 |
| 65 | MP0005075_abnormal_melanosome_morpholog | 1.04861031 |
| 66 | MP0002405_respiratory_system_inflammati | 1.04685492 |
| 67 | MP0000703_abnormal_thymus_morphology | 1.03586482 |
| 68 | MP0002722_abnormal_immune_system | 1.01576484 |
| 69 | MP0001764_abnormal_homeostasis | 1.01293103 |
| 70 | MP0003718_maternal_effect | 0.96418815 |
| 71 | MP0001845_abnormal_inflammatory_respons | 0.96074962 |
| 72 | MP0006276_abnormal_autonomic_nervous | 0.95928937 |
| 73 | MP0001188_hyperpigmentation | 0.95801180 |
| 74 | MP0002429_abnormal_blood_cell | 0.95584816 |
| 75 | MP0002693_abnormal_pancreas_physiology | 0.94325804 |
| 76 | MP0002837_dystrophic_cardiac_calcinosis | 0.92454734 |
| 77 | MP0004142_abnormal_muscle_tone | 0.90949314 |
| 78 | MP0005636_abnormal_mineral_homeostasis | 0.90229085 |
| 79 | MP0002160_abnormal_reproductive_system | 0.89962864 |
| 80 | MP0006035_abnormal_mitochondrial_morpho | 0.89638533 |
| 81 | MP0004885_abnormal_endolymph | 0.88458401 |
| 82 | MP0003252_abnormal_bile_duct | 0.88432105 |
| 83 | MP0005464_abnormal_platelet_physiology | 0.86305204 |
| 84 | MP0005379_endocrine/exocrine_gland_phen | 0.84426191 |
| 85 | MP0002638_abnormal_pupillary_reflex | 0.84405852 |
| 86 | MP0010155_abnormal_intestine_physiology | 0.83466523 |
| 87 | MP0009764_decreased_sensitivity_to | 0.82709764 |
| 88 | MP0010094_abnormal_chromosome_stability | 0.81890997 |
| 89 | MP0002933_joint_inflammation | 0.80469544 |
| 90 | MP0001501_abnormal_sleep_pattern | 0.79264635 |
| 91 | MP0005167_abnormal_blood-brain_barrier | 0.77184685 |
| 92 | MP0001119_abnormal_female_reproductive | 0.76874715 |
| 93 | MP0004742_abnormal_vestibular_system | 0.76733297 |
| 94 | MP0009745_abnormal_behavioral_response | 0.76350979 |
| 95 | MP0000631_abnormal_neuroendocrine_gland | 0.75668974 |
| 96 | MP0001853_heart_inflammation | 0.74150506 |
| 97 | MP0003880_abnormal_central_pattern | 0.74064192 |
| 98 | MP0001765_abnormal_ion_homeostasis | 0.74022628 |
| 99 | MP0002272_abnormal_nervous_system | 0.71117133 |
| 100 | MP0000613_abnormal_salivary_gland | 0.70451629 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.56144911 |
| 2 | Aplastic anemia (HP:0001915) | 4.25227141 |
| 3 | Mitochondrial inheritance (HP:0001427) | 4.21988216 |
| 4 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.16135590 |
| 5 | Acute encephalopathy (HP:0006846) | 4.10468110 |
| 6 | Progressive macrocephaly (HP:0004481) | 3.74249622 |
| 7 | Increased CSF lactate (HP:0002490) | 3.73346807 |
| 8 | Hepatocellular necrosis (HP:0001404) | 3.64716470 |
| 9 | IgG deficiency (HP:0004315) | 3.62657983 |
| 10 | T lymphocytopenia (HP:0005403) | 3.49242890 |
| 11 | Abnormality of T cell number (HP:0011839) | 3.43364622 |
| 12 | Congenital stationary night blindness (HP:0007642) | 3.36978711 |
| 13 | Severe combined immunodeficiency (HP:0004430) | 3.31851376 |
| 14 | Hepatic necrosis (HP:0002605) | 3.31600758 |
| 15 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.23597397 |
| 16 | Cerebral edema (HP:0002181) | 3.23205643 |
| 17 | Hypoproteinemia (HP:0003075) | 3.08587522 |
| 18 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.97056696 |
| 19 | Abnormality of B cell number (HP:0010975) | 2.93714558 |
| 20 | Abnormality of the prostate (HP:0008775) | 2.91007762 |
| 21 | Pancreatic cysts (HP:0001737) | 2.89629987 |
| 22 | Abolished electroretinogram (ERG) (HP:0000550) | 2.86951616 |
| 23 | Increased hepatocellular lipid droplets (HP:0006565) | 2.85855996 |
| 24 | Molar tooth sign on MRI (HP:0002419) | 2.84893227 |
| 25 | Abnormality of midbrain morphology (HP:0002418) | 2.84893227 |
| 26 | 3-Methylglutaconic aciduria (HP:0003535) | 2.76842443 |
| 27 | Optic disc pallor (HP:0000543) | 2.75409122 |
| 28 | Abnormality of T cells (HP:0002843) | 2.74150226 |
| 29 | Renal Fanconi syndrome (HP:0001994) | 2.73840535 |
| 30 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.72964766 |
| 31 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.72964766 |
| 32 | Autoimmune hemolytic anemia (HP:0001890) | 2.72246057 |
| 33 | Type 2 muscle fiber atrophy (HP:0003554) | 2.64772245 |
| 34 | Lipid accumulation in hepatocytes (HP:0006561) | 2.63938317 |
| 35 | Combined immunodeficiency (HP:0005387) | 2.63833562 |
| 36 | Pancytopenia (HP:0001876) | 2.61813906 |
| 37 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.61223714 |
| 38 | Increased intramyocellular lipid droplets (HP:0012240) | 2.60653541 |
| 39 | Increased serum lactate (HP:0002151) | 2.59359506 |
| 40 | Pancreatic fibrosis (HP:0100732) | 2.58528396 |
| 41 | B lymphocytopenia (HP:0010976) | 2.55472281 |
| 42 | Stomatitis (HP:0010280) | 2.55307951 |
| 43 | Attenuation of retinal blood vessels (HP:0007843) | 2.53560214 |
| 44 | Thyroiditis (HP:0100646) | 2.53014307 |
| 45 | Increased IgM level (HP:0003496) | 2.50242298 |
| 46 | Lactic acidosis (HP:0003128) | 2.45359871 |
| 47 | Lethargy (HP:0001254) | 2.43628968 |
| 48 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.42939621 |
| 49 | True hermaphroditism (HP:0010459) | 2.36444811 |
| 50 | Pendular nystagmus (HP:0012043) | 2.36063982 |
| 51 | Decreased central vision (HP:0007663) | 2.27910336 |
| 52 | Muscle fiber atrophy (HP:0100295) | 2.26737492 |
| 53 | Abnormality of eosinophils (HP:0001879) | 2.24041719 |
| 54 | Methylmalonic acidemia (HP:0002912) | 2.23124414 |
| 55 | Type I transferrin isoform profile (HP:0003642) | 2.17218327 |
| 56 | Nephronophthisis (HP:0000090) | 2.15960282 |
| 57 | Agammaglobulinemia (HP:0004432) | 2.15410358 |
| 58 | Panhypogammaglobulinemia (HP:0003139) | 2.13984864 |
| 59 | Increased muscle lipid content (HP:0009058) | 2.13463056 |
| 60 | Respiratory failure (HP:0002878) | 2.13128768 |
| 61 | Methylmalonic aciduria (HP:0012120) | 2.07976920 |
| 62 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.06498898 |
| 63 | Absent thumb (HP:0009777) | 2.04872244 |
| 64 | Hyperglycinemia (HP:0002154) | 1.99153258 |
| 65 | Exercise intolerance (HP:0003546) | 1.94686741 |
| 66 | Recurrent cutaneous fungal infections (HP:0011370) | 1.94236892 |
| 67 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.94236892 |
| 68 | Abnormal number of erythroid precursors (HP:0012131) | 1.93813231 |
| 69 | Cerebral palsy (HP:0100021) | 1.93089984 |
| 70 | Constricted visual fields (HP:0001133) | 1.92883241 |
| 71 | Chronic diarrhea (HP:0002028) | 1.92472058 |
| 72 | Abnormality of the renal cortex (HP:0011035) | 1.91341412 |
| 73 | Congenital, generalized hypertrichosis (HP:0004540) | 1.90740421 |
| 74 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.90158074 |
| 75 | Leukodystrophy (HP:0002415) | 1.89349092 |
| 76 | Exertional dyspnea (HP:0002875) | 1.89180003 |
| 77 | Encephalitis (HP:0002383) | 1.84884905 |
| 78 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.82412584 |
| 79 | Eosinophilia (HP:0001880) | 1.78732357 |
| 80 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.78656642 |
| 81 | Hypoalbuminemia (HP:0003073) | 1.78433162 |
| 82 | Abnormal albumin level (HP:0012116) | 1.78433162 |
| 83 | Abnormality of T cell physiology (HP:0011840) | 1.78311891 |
| 84 | Reticulocytopenia (HP:0001896) | 1.78157510 |
| 85 | Abnormality of the renal medulla (HP:0100957) | 1.78151616 |
| 86 | Autoimmune thrombocytopenia (HP:0001973) | 1.76711561 |
| 87 | Ketosis (HP:0001946) | 1.75820893 |
| 88 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.74567609 |
| 89 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.74567609 |
| 90 | Abnormal protein glycosylation (HP:0012346) | 1.74567609 |
| 91 | Abnormal glycosylation (HP:0012345) | 1.74567609 |
| 92 | Abnormal drinking behavior (HP:0030082) | 1.72336578 |
| 93 | Polydipsia (HP:0001959) | 1.72336578 |
| 94 | Prostate neoplasm (HP:0100787) | 1.71355537 |
| 95 | Severe visual impairment (HP:0001141) | 1.71304661 |
| 96 | Dicarboxylic aciduria (HP:0003215) | 1.70700884 |
| 97 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.70700884 |
| 98 | Medial flaring of the eyebrow (HP:0010747) | 1.70356885 |
| 99 | Colon cancer (HP:0003003) | 1.70064218 |
| 100 | Oral leukoplakia (HP:0002745) | 1.69086465 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 4.72810100 |
| 2 | TESK2 | 4.04766344 |
| 3 | KDR | 3.72370134 |
| 4 | TAOK3 | 3.05467608 |
| 5 | BCKDK | 2.96931805 |
| 6 | ZAK | 2.93199305 |
| 7 | VRK2 | 2.68133852 |
| 8 | TLK1 | 2.60775762 |
| 9 | MST4 | 2.40403632 |
| 10 | GRK1 | 2.32751304 |
| 11 | TIE1 | 2.29995858 |
| 12 | BUB1 | 2.29917840 |
| 13 | MAP4K2 | 2.22858581 |
| 14 | ADRBK2 | 2.15283556 |
| 15 | NUAK1 | 2.08205250 |
| 16 | MAP4K1 | 1.99306910 |
| 17 | WNK4 | 1.80881854 |
| 18 | BMPR1B | 1.75237374 |
| 19 | ITK | 1.74856182 |
| 20 | VRK1 | 1.68227433 |
| 21 | LIMK1 | 1.56020766 |
| 22 | TEC | 1.55285672 |
| 23 | STK16 | 1.52917896 |
| 24 | FRK | 1.32123176 |
| 25 | MAP3K12 | 1.22955382 |
| 26 | TESK1 | 1.18640018 |
| 27 | EIF2AK3 | 1.18534992 |
| 28 | FES | 1.18071153 |
| 29 | SYK | 1.15343742 |
| 30 | PINK1 | 1.14022448 |
| 31 | CDK19 | 1.11888735 |
| 32 | MAPKAPK3 | 1.11562642 |
| 33 | NME1 | 1.07366289 |
| 34 | PRKCQ | 0.99841712 |
| 35 | KIT | 0.90868648 |
| 36 | MUSK | 0.88340640 |
| 37 | BTK | 0.83400571 |
| 38 | TAF1 | 0.82582962 |
| 39 | GRK7 | 0.82207354 |
| 40 | CSNK1G1 | 0.82187953 |
| 41 | WNK3 | 0.81930566 |
| 42 | OXSR1 | 0.81812647 |
| 43 | CDC7 | 0.81639067 |
| 44 | TNK2 | 0.79740819 |
| 45 | MAP3K11 | 0.79194804 |
| 46 | CSNK1G3 | 0.78946608 |
| 47 | STK39 | 0.78643664 |
| 48 | LCK | 0.77441634 |
| 49 | MAPK13 | 0.76208685 |
| 50 | IKBKB | 0.71190226 |
| 51 | CSF1R | 0.70841325 |
| 52 | DYRK2 | 0.70469235 |
| 53 | SRPK1 | 0.70332867 |
| 54 | DAPK1 | 0.70143059 |
| 55 | AURKA | 0.69210607 |
| 56 | SCYL2 | 0.67251560 |
| 57 | INSRR | 0.67037243 |
| 58 | PLK4 | 0.64200744 |
| 59 | RPS6KA5 | 0.63377044 |
| 60 | TRIM28 | 0.62872661 |
| 61 | LYN | 0.62533957 |
| 62 | MKNK2 | 0.62303132 |
| 63 | CSNK1G2 | 0.57006136 |
| 64 | CDK8 | 0.55736381 |
| 65 | MYLK | 0.52344333 |
| 66 | MKNK1 | 0.51831847 |
| 67 | PIK3CA | 0.50916263 |
| 68 | GRK6 | 0.50802518 |
| 69 | EIF2AK2 | 0.50168399 |
| 70 | CSK | 0.49941659 |
| 71 | PLK3 | 0.49184498 |
| 72 | ADRBK1 | 0.48711253 |
| 73 | ATR | 0.47249214 |
| 74 | IKBKE | 0.46919693 |
| 75 | PLK1 | 0.46661241 |
| 76 | CSNK1A1L | 0.45048510 |
| 77 | MATK | 0.44802018 |
| 78 | AURKB | 0.43943592 |
| 79 | PHKG1 | 0.43176497 |
| 80 | PHKG2 | 0.43176497 |
| 81 | PLK2 | 0.41378646 |
| 82 | PASK | 0.40543870 |
| 83 | PIK3CG | 0.39488781 |
| 84 | IGF1R | 0.39131106 |
| 85 | CSNK2A1 | 0.39111041 |
| 86 | RPS6KA4 | 0.38961108 |
| 87 | OBSCN | 0.36721896 |
| 88 | PRKCA | 0.36483223 |
| 89 | PRKACA | 0.35099504 |
| 90 | PIM2 | 0.35090158 |
| 91 | MAP2K6 | 0.34835516 |
| 92 | CAMKK2 | 0.34178701 |
| 93 | PIM1 | 0.33033414 |
| 94 | CSNK2A2 | 0.32865437 |
| 95 | BCR | 0.31953368 |
| 96 | NEK1 | 0.30800034 |
| 97 | PRKCG | 0.29850997 |
| 98 | CAMK2A | 0.28426565 |
| 99 | ROCK1 | 0.27799376 |
| 100 | EIF2AK1 | 0.27512239 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.95429558 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.93396227 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.64499964 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.21782238 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 2.66246897 |
| 6 | Ribosome_Homo sapiens_hsa03010 | 2.65025199 |
| 7 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.23302574 |
| 8 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.13452382 |
| 9 | Protein export_Homo sapiens_hsa03060 | 2.12777316 |
| 10 | Alzheimers disease_Homo sapiens_hsa05010 | 2.10143346 |
| 11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.01172318 |
| 12 | Homologous recombination_Homo sapiens_hsa03440 | 1.99425059 |
| 13 | Allograft rejection_Homo sapiens_hsa05330 | 1.99080381 |
| 14 | Huntingtons disease_Homo sapiens_hsa05016 | 1.94862515 |
| 15 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.87549253 |
| 16 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.80604567 |
| 17 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.79275371 |
| 18 | Phototransduction_Homo sapiens_hsa04744 | 1.62086085 |
| 19 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.56813452 |
| 20 | Asthma_Homo sapiens_hsa05310 | 1.53603148 |
| 21 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.53546580 |
| 22 | Mismatch repair_Homo sapiens_hsa03430 | 1.42018051 |
| 23 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.41412892 |
| 24 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.40830015 |
| 25 | DNA replication_Homo sapiens_hsa03030 | 1.35466464 |
| 26 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.35366798 |
| 27 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.34301683 |
| 28 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.33680960 |
| 29 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.32286726 |
| 30 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.31391572 |
| 31 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.30843302 |
| 32 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.30317751 |
| 33 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.27085830 |
| 34 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.26314182 |
| 35 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.26165697 |
| 36 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.22928449 |
| 37 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.20217822 |
| 38 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.15917379 |
| 39 | Peroxisome_Homo sapiens_hsa04146 | 1.13875099 |
| 40 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.08463248 |
| 41 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.04279346 |
| 42 | Purine metabolism_Homo sapiens_hsa00230 | 1.03708828 |
| 43 | RNA degradation_Homo sapiens_hsa03018 | 1.03183674 |
| 44 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.01690852 |
| 45 | Base excision repair_Homo sapiens_hsa03410 | 0.99816813 |
| 46 | Spliceosome_Homo sapiens_hsa03040 | 0.95209608 |
| 47 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.94854644 |
| 48 | Basal transcription factors_Homo sapiens_hsa03022 | 0.94452489 |
| 49 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.94357545 |
| 50 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.93736326 |
| 51 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.92391111 |
| 52 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.81146712 |
| 53 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.80375752 |
| 54 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.79273838 |
| 55 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.77435348 |
| 56 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.76767747 |
| 57 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.73959717 |
| 58 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.71620952 |
| 59 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.68675266 |
| 60 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.68486804 |
| 61 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.63906604 |
| 62 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.62217558 |
| 63 | Olfactory transduction_Homo sapiens_hsa04740 | 0.60435687 |
| 64 | Metabolic pathways_Homo sapiens_hsa01100 | 0.60091387 |
| 65 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.60080775 |
| 66 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.56877949 |
| 67 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.56150929 |
| 68 | Retinol metabolism_Homo sapiens_hsa00830 | 0.55353843 |
| 69 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.55290708 |
| 70 | RNA transport_Homo sapiens_hsa03013 | 0.54727517 |
| 71 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.53769396 |
| 72 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.52820883 |
| 73 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.51899699 |
| 74 | Measles_Homo sapiens_hsa05162 | 0.50264224 |
| 75 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.49771175 |
| 76 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.49727931 |
| 77 | Viral myocarditis_Homo sapiens_hsa05416 | 0.48055124 |
| 78 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.46996956 |
| 79 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.45817002 |
| 80 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.44542821 |
| 81 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.39962232 |
| 82 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.39009933 |
| 83 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.39000860 |
| 84 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.38844794 |
| 85 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.38710349 |
| 86 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.35786537 |
| 87 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.32791110 |
| 88 | Sulfur relay system_Homo sapiens_hsa04122 | 0.31784622 |
| 89 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.31204603 |
| 90 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.30182032 |
| 91 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.29521526 |
| 92 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.29146417 |
| 93 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.28124731 |
| 94 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.27806811 |
| 95 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.27702011 |
| 96 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.26748965 |
| 97 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.26351058 |
| 98 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.24318951 |
| 99 | Taste transduction_Homo sapiens_hsa04742 | 0.24262723 |
| 100 | Alcoholism_Homo sapiens_hsa05034 | 0.22923851 |

