

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | chaperone-mediated protein transport (GO:0072321) | 5.43982029 |
| 2 | DNA deamination (GO:0045006) | 5.34545094 |
| 3 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.87252608 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 4.81153749 |
| 5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.81153749 |
| 6 | ribosomal small subunit assembly (GO:0000028) | 4.77161789 |
| 7 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.75380867 |
| 8 | behavioral response to nicotine (GO:0035095) | 4.52481347 |
| 9 | protein complex biogenesis (GO:0070271) | 4.42081226 |
| 10 | protein neddylation (GO:0045116) | 4.23034234 |
| 11 | maturation of SSU-rRNA (GO:0030490) | 4.22546264 |
| 12 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.13813543 |
| 13 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.13114041 |
| 14 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.08007080 |
| 15 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.00853515 |
| 16 | NADH dehydrogenase complex assembly (GO:0010257) | 4.00853515 |
| 17 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.00853515 |
| 18 | pattern specification involved in kidney development (GO:0061004) | 3.90004353 |
| 19 | protein-cofactor linkage (GO:0018065) | 3.88045851 |
| 20 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.87993211 |
| 21 | respiratory electron transport chain (GO:0022904) | 3.83382562 |
| 22 | electron transport chain (GO:0022900) | 3.82940632 |
| 23 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.70748085 |
| 24 | viral transcription (GO:0019083) | 3.68132356 |
| 25 | regulation of chronic inflammatory response (GO:0002676) | 3.65233074 |
| 26 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.64367014 |
| 27 | cytidine deamination (GO:0009972) | 3.57562617 |
| 28 | cytidine metabolic process (GO:0046087) | 3.57562617 |
| 29 | cytidine catabolic process (GO:0006216) | 3.57562617 |
| 30 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.56120835 |
| 31 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.56120835 |
| 32 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.56120835 |
| 33 | ubiquinone biosynthetic process (GO:0006744) | 3.53761490 |
| 34 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.53172692 |
| 35 | translational termination (GO:0006415) | 3.52136037 |
| 36 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.51796792 |
| 37 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.51796792 |
| 38 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.50403213 |
| 39 | sequestering of actin monomers (GO:0042989) | 3.47367522 |
| 40 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.43174577 |
| 41 | cotranslational protein targeting to membrane (GO:0006613) | 3.42629015 |
| 42 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.42122390 |
| 43 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.39543456 |
| 44 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.39543456 |
| 45 | protein targeting to ER (GO:0045047) | 3.36656243 |
| 46 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.33399780 |
| 47 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.25687566 |
| 48 | ubiquinone metabolic process (GO:0006743) | 3.25033460 |
| 49 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.22785040 |
| 50 | nonmotile primary cilium assembly (GO:0035058) | 3.20535458 |
| 51 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.20182112 |
| 52 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.18736549 |
| 53 | proteasome assembly (GO:0043248) | 3.18172939 |
| 54 | positive regulation of prostaglandin secretion (GO:0032308) | 3.17247668 |
| 55 | somite development (GO:0061053) | 3.15318760 |
| 56 | protein localization to endoplasmic reticulum (GO:0070972) | 3.15169403 |
| 57 | translational elongation (GO:0006414) | 3.10437668 |
| 58 | base-excision repair, AP site formation (GO:0006285) | 3.07526917 |
| 59 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.03442829 |
| 60 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.03442829 |
| 61 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.02829755 |
| 62 | negative regulation of ligase activity (GO:0051352) | 3.02829755 |
| 63 | hydrogen ion transmembrane transport (GO:1902600) | 3.01815621 |
| 64 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.00518044 |
| 65 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.99575687 |
| 66 | spliceosomal complex assembly (GO:0000245) | 2.97711922 |
| 67 | protein deneddylation (GO:0000338) | 2.96791084 |
| 68 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.96599179 |
| 69 | termination of RNA polymerase III transcription (GO:0006386) | 2.96599179 |
| 70 | maturation of 5.8S rRNA (GO:0000460) | 2.95829765 |
| 71 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.95329025 |
| 72 | regulation of mitochondrial translation (GO:0070129) | 2.94090666 |
| 73 | cullin deneddylation (GO:0010388) | 2.93064733 |
| 74 | platelet dense granule organization (GO:0060155) | 2.92597159 |
| 75 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.91659084 |
| 76 | translation (GO:0006412) | 2.89579700 |
| 77 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.88400082 |
| 78 | replication fork processing (GO:0031297) | 2.86354213 |
| 79 | quinone biosynthetic process (GO:1901663) | 2.85286368 |
| 80 | protein peptidyl-prolyl isomerization (GO:0000413) | 2.85065861 |
| 81 | cytochrome complex assembly (GO:0017004) | 2.85031793 |
| 82 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.84281406 |
| 83 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.84281406 |
| 84 | metallo-sulfur cluster assembly (GO:0031163) | 2.82478513 |
| 85 | iron-sulfur cluster assembly (GO:0016226) | 2.82478513 |
| 86 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.81259781 |
| 87 | proton transport (GO:0015992) | 2.81232501 |
| 88 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.81110476 |
| 89 | chromatin remodeling at centromere (GO:0031055) | 2.80309063 |
| 90 | ribosomal small subunit biogenesis (GO:0042274) | 2.79674629 |
| 91 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.79141771 |
| 92 | GTP biosynthetic process (GO:0006183) | 2.79081341 |
| 93 | peptidyl-histidine modification (GO:0018202) | 2.78165951 |
| 94 | positive regulation of cell cycle arrest (GO:0071158) | 2.78023829 |
| 95 | intracellular protein transmembrane import (GO:0044743) | 2.77523729 |
| 96 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.76627282 |
| 97 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.75416933 |
| 98 | hydrogen transport (GO:0006818) | 2.74453478 |
| 99 | cellular component biogenesis (GO:0044085) | 2.71429258 |
| 100 | rRNA catabolic process (GO:0016075) | 2.69235537 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.99458986 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.30531861 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.22839594 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.82900025 |
| 5 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.45251742 |
| 6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.02113564 |
| 7 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.95574074 |
| 8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.89143455 |
| 9 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.76237966 |
| 10 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.66395906 |
| 11 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.62622674 |
| 12 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.29896108 |
| 13 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.28222345 |
| 14 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.20063706 |
| 15 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.17576611 |
| 16 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.15782610 |
| 17 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.14649196 |
| 18 | VDR_22108803_ChIP-Seq_LS180_Human | 2.13289786 |
| 19 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.10658798 |
| 20 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.09534478 |
| 21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.97370380 |
| 22 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.89846549 |
| 23 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.87836153 |
| 24 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.84882544 |
| 25 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.82087695 |
| 26 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.81393939 |
| 27 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.75189403 |
| 28 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.72783644 |
| 29 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.71176558 |
| 30 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.69781115 |
| 31 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.65098310 |
| 32 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.62603080 |
| 33 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.57590934 |
| 34 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.57132923 |
| 35 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.53241161 |
| 36 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.45292748 |
| 37 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.45013731 |
| 38 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.41459785 |
| 39 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.40252095 |
| 40 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.34919258 |
| 41 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.32070274 |
| 42 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.30839091 |
| 43 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.29104804 |
| 44 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.27532675 |
| 45 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.27342424 |
| 46 | EWS_26573619_Chip-Seq_HEK293_Human | 1.25625475 |
| 47 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.21798977 |
| 48 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.21126751 |
| 49 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.18023043 |
| 50 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.17503100 |
| 51 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.15976472 |
| 52 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.15464963 |
| 53 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.15340194 |
| 54 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.13556382 |
| 55 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.12760097 |
| 56 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.12760097 |
| 57 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.12203813 |
| 58 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.12186438 |
| 59 | AR_20517297_ChIP-Seq_VCAP_Human | 1.08075920 |
| 60 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.07319272 |
| 61 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.07234770 |
| 62 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.07234770 |
| 63 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.07024515 |
| 64 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.06085859 |
| 65 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.05990098 |
| 66 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.04462111 |
| 67 | NCOR_22424771_ChIP-Seq_293T_Human | 1.03327804 |
| 68 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.02645581 |
| 69 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.02611390 |
| 70 | ERA_21632823_ChIP-Seq_H3396_Human | 1.02415902 |
| 71 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.01896357 |
| 72 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.01728369 |
| 73 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.00574230 |
| 74 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.99034921 |
| 75 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.98025869 |
| 76 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.97115878 |
| 77 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.96349163 |
| 78 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.95118137 |
| 79 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.93770470 |
| 80 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.93682338 |
| 81 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.93279711 |
| 82 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.93115840 |
| 83 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.92977944 |
| 84 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.92469949 |
| 85 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.92277608 |
| 86 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.91952344 |
| 87 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.90118198 |
| 88 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.88346906 |
| 89 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.86887975 |
| 90 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.86745964 |
| 91 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.85861238 |
| 92 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.85252371 |
| 93 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.84700282 |
| 94 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.84451748 |
| 95 | FUS_26573619_Chip-Seq_HEK293_Human | 0.84231555 |
| 96 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.84094681 |
| 97 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.84017000 |
| 98 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.83900520 |
| 99 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.82975381 |
| 100 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.80579173 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 3.21480319 |
| 2 | MP0008789_abnormal_olfactory_epithelium | 2.87235512 |
| 3 | MP0006292_abnormal_olfactory_placode | 2.60537173 |
| 4 | MP0002102_abnormal_ear_morphology | 2.60535144 |
| 5 | MP0002653_abnormal_ependyma_morphology | 2.54932333 |
| 6 | MP0008877_abnormal_DNA_methylation | 2.40554260 |
| 7 | MP0001348_abnormal_lacrimal_gland | 2.35773381 |
| 8 | MP0005394_taste/olfaction_phenotype | 2.27629172 |
| 9 | MP0005499_abnormal_olfactory_system | 2.27629172 |
| 10 | MP0002163_abnormal_gland_morphology | 2.24224978 |
| 11 | MP0004147_increased_porphyrin_level | 2.23380318 |
| 12 | MP0002638_abnormal_pupillary_reflex | 2.17642107 |
| 13 | MP0005377_hearing/vestibular/ear_phenot | 2.15773444 |
| 14 | MP0003878_abnormal_ear_physiology | 2.15773444 |
| 15 | MP0005645_abnormal_hypothalamus_physiol | 2.14946106 |
| 16 | MP0005671_abnormal_response_to | 2.13415826 |
| 17 | MP0003646_muscle_fatigue | 2.06748570 |
| 18 | MP0001968_abnormal_touch/_nociception | 2.03261730 |
| 19 | MP0000569_abnormal_digit_pigmentation | 2.02200647 |
| 20 | MP0000685_abnormal_immune_system | 2.01310520 |
| 21 | MP0001529_abnormal_vocalization | 1.97056722 |
| 22 | MP0003011_delayed_dark_adaptation | 1.92879870 |
| 23 | MP0008872_abnormal_physiological_respon | 1.89685311 |
| 24 | MP0001905_abnormal_dopamine_level | 1.80660968 |
| 25 | MP0001984_abnormal_olfaction | 1.79603247 |
| 26 | MP0004145_abnormal_muscle_electrophysio | 1.79208421 |
| 27 | MP0006072_abnormal_retinal_apoptosis | 1.77795537 |
| 28 | MP0005551_abnormal_eye_electrophysiolog | 1.73628190 |
| 29 | MP0002138_abnormal_hepatobiliary_system | 1.68134859 |
| 30 | MP0008875_abnormal_xenobiotic_pharmacok | 1.66137192 |
| 31 | MP0003880_abnormal_central_pattern | 1.65520745 |
| 32 | MP0002876_abnormal_thyroid_physiology | 1.60740462 |
| 33 | MP0005084_abnormal_gallbladder_morpholo | 1.60599005 |
| 34 | MP0008058_abnormal_DNA_repair | 1.57419643 |
| 35 | MP0003787_abnormal_imprinting | 1.56781953 |
| 36 | MP0002095_abnormal_skin_pigmentation | 1.56274944 |
| 37 | MP0004142_abnormal_muscle_tone | 1.53144042 |
| 38 | MP0001293_anophthalmia | 1.52970055 |
| 39 | MP0002736_abnormal_nociception_after | 1.50128740 |
| 40 | MP0003121_genomic_imprinting | 1.48800231 |
| 41 | MP0009745_abnormal_behavioral_response | 1.42086318 |
| 42 | MP0001501_abnormal_sleep_pattern | 1.39804838 |
| 43 | MP0001919_abnormal_reproductive_system | 1.37979591 |
| 44 | MP0005389_reproductive_system_phenotype | 1.34546440 |
| 45 | MP0006276_abnormal_autonomic_nervous | 1.29933270 |
| 46 | MP0002272_abnormal_nervous_system | 1.29208027 |
| 47 | MP0002234_abnormal_pharynx_morphology | 1.25613840 |
| 48 | MP0005379_endocrine/exocrine_gland_phen | 1.22897319 |
| 49 | MP0002557_abnormal_social/conspecific_i | 1.22714198 |
| 50 | MP0005253_abnormal_eye_physiology | 1.21444132 |
| 51 | MP0003195_calcinosis | 1.16384657 |
| 52 | MP0001986_abnormal_taste_sensitivity | 1.15625549 |
| 53 | MP0003122_maternal_imprinting | 1.14858740 |
| 54 | MP0000778_abnormal_nervous_system | 1.14708624 |
| 55 | MP0001485_abnormal_pinna_reflex | 1.08705446 |
| 56 | MP0003136_yellow_coat_color | 1.08197814 |
| 57 | MP0001502_abnormal_circadian_rhythm | 1.07792551 |
| 58 | MP0010094_abnormal_chromosome_stability | 1.07145643 |
| 59 | MP0002733_abnormal_thermal_nociception | 1.06859349 |
| 60 | MP0003693_abnormal_embryo_hatching | 1.06618135 |
| 61 | MP0009046_muscle_twitch | 1.06447010 |
| 62 | MP0003806_abnormal_nucleotide_metabolis | 1.02777982 |
| 63 | MP0001835_abnormal_antigen_presentation | 1.02052114 |
| 64 | MP0000049_abnormal_middle_ear | 1.01932588 |
| 65 | MP0002277_abnormal_respiratory_mucosa | 0.99091797 |
| 66 | MP0001970_abnormal_pain_threshold | 0.97560567 |
| 67 | MP0001440_abnormal_grooming_behavior | 0.97379432 |
| 68 | MP0000631_abnormal_neuroendocrine_gland | 0.96747322 |
| 69 | MP0005195_abnormal_posterior_eye | 0.96728358 |
| 70 | MP0002735_abnormal_chemical_nociception | 0.96670305 |
| 71 | MP0002184_abnormal_innervation | 0.95034387 |
| 72 | MP0002837_dystrophic_cardiac_calcinosis | 0.94925355 |
| 73 | MP0001188_hyperpigmentation | 0.93475405 |
| 74 | MP0004885_abnormal_endolymph | 0.93375655 |
| 75 | MP0000427_abnormal_hair_cycle | 0.92123799 |
| 76 | MP0002148_abnormal_hypersensitivity_rea | 0.90980905 |
| 77 | MP0005646_abnormal_pituitary_gland | 0.90711806 |
| 78 | MP0008995_early_reproductive_senescence | 0.89958875 |
| 79 | MP0005174_abnormal_tail_pigmentation | 0.86335936 |
| 80 | MP0004742_abnormal_vestibular_system | 0.85701978 |
| 81 | MP0002160_abnormal_reproductive_system | 0.84863968 |
| 82 | MP0002752_abnormal_somatic_nervous | 0.84331454 |
| 83 | MP0000372_irregular_coat_pigmentation | 0.83560870 |
| 84 | MP0001486_abnormal_startle_reflex | 0.83048114 |
| 85 | MP0002210_abnormal_sex_determination | 0.82629220 |
| 86 | MP0002572_abnormal_emotion/affect_behav | 0.81963063 |
| 87 | MP0009333_abnormal_splenocyte_physiolog | 0.81953159 |
| 88 | MP0005387_immune_system_phenotype | 0.80974932 |
| 89 | MP0001790_abnormal_immune_system | 0.80974932 |
| 90 | MP0002282_abnormal_trachea_morphology | 0.80080810 |
| 91 | MP0002063_abnormal_learning/memory/cond | 0.76661553 |
| 92 | MP0009764_decreased_sensitivity_to | 0.76181257 |
| 93 | MP0001542_abnormal_bone_strength | 0.75963297 |
| 94 | MP0003936_abnormal_reproductive_system | 0.74688561 |
| 95 | MP0000026_abnormal_inner_ear | 0.73788562 |
| 96 | MP0003186_abnormal_redox_activity | 0.72650765 |
| 97 | MP0002067_abnormal_sensory_capabilities | 0.70130654 |
| 98 | MP0000566_synostosis | 0.69047282 |
| 99 | MP0003635_abnormal_synaptic_transmissio | 0.68969605 |
| 100 | MP0004924_abnormal_behavior | 0.68568223 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 5.10571926 |
| 2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.55606762 |
| 3 | Acute encephalopathy (HP:0006846) | 4.32774676 |
| 4 | 3-Methylglutaconic aciduria (HP:0003535) | 4.25841083 |
| 5 | Molar tooth sign on MRI (HP:0002419) | 4.18103782 |
| 6 | Abnormality of midbrain morphology (HP:0002418) | 4.18103782 |
| 7 | Progressive macrocephaly (HP:0004481) | 4.14054210 |
| 8 | Mitochondrial inheritance (HP:0001427) | 4.10444449 |
| 9 | Pancreatic cysts (HP:0001737) | 3.80095133 |
| 10 | Increased CSF lactate (HP:0002490) | 3.72804306 |
| 11 | Congenital, generalized hypertrichosis (HP:0004540) | 3.58248807 |
| 12 | Hepatocellular necrosis (HP:0001404) | 3.46090380 |
| 13 | Hepatic necrosis (HP:0002605) | 3.18338319 |
| 14 | Pancreatic fibrosis (HP:0100732) | 3.15925394 |
| 15 | Supernumerary spleens (HP:0009799) | 3.08797289 |
| 16 | Cerebral edema (HP:0002181) | 3.08750006 |
| 17 | Colon cancer (HP:0003003) | 2.98679654 |
| 18 | Increased hepatocellular lipid droplets (HP:0006565) | 2.92277360 |
| 19 | Tubular atrophy (HP:0000092) | 2.87858544 |
| 20 | Oligodactyly (hands) (HP:0001180) | 2.87072546 |
| 21 | Congenital stationary night blindness (HP:0007642) | 2.86348733 |
| 22 | True hermaphroditism (HP:0010459) | 2.84757591 |
| 23 | Nephronophthisis (HP:0000090) | 2.76238531 |
| 24 | Lipid accumulation in hepatocytes (HP:0006561) | 2.75034078 |
| 25 | Rib fusion (HP:0000902) | 2.75017082 |
| 26 | Abnormality of the labia minora (HP:0012880) | 2.71026677 |
| 27 | Reticulocytopenia (HP:0001896) | 2.68764417 |
| 28 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.66668911 |
| 29 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.66135593 |
| 30 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.65619614 |
| 31 | Optic disc pallor (HP:0000543) | 2.63767564 |
| 32 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.55438051 |
| 33 | Hypoproteinemia (HP:0003075) | 2.46786280 |
| 34 | Oligodactyly (HP:0012165) | 2.44955449 |
| 35 | Abnormality of the renal medulla (HP:0100957) | 2.42730387 |
| 36 | Medial flaring of the eyebrow (HP:0010747) | 2.41325364 |
| 37 | Increased serum lactate (HP:0002151) | 2.40102318 |
| 38 | Absent thumb (HP:0009777) | 2.37241462 |
| 39 | Renal Fanconi syndrome (HP:0001994) | 2.35605378 |
| 40 | Leukodystrophy (HP:0002415) | 2.35570071 |
| 41 | Bile duct proliferation (HP:0001408) | 2.32964842 |
| 42 | Abnormal biliary tract physiology (HP:0012439) | 2.32964842 |
| 43 | Abnormality of the pons (HP:0007361) | 2.32863394 |
| 44 | Abnormal number of erythroid precursors (HP:0012131) | 2.31976970 |
| 45 | Type II lissencephaly (HP:0007260) | 2.31567975 |
| 46 | Cystic liver disease (HP:0006706) | 2.27047675 |
| 47 | Macrocytic anemia (HP:0001972) | 2.26426654 |
| 48 | Abnormal drinking behavior (HP:0030082) | 2.25428987 |
| 49 | Polydipsia (HP:0001959) | 2.25428987 |
| 50 | Abnormality of the renal cortex (HP:0011035) | 2.25396668 |
| 51 | Lactic acidosis (HP:0003128) | 2.24710212 |
| 52 | Fibular aplasia (HP:0002990) | 2.21682544 |
| 53 | Increased intramyocellular lipid droplets (HP:0012240) | 2.09737521 |
| 54 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.09071252 |
| 55 | Male pseudohermaphroditism (HP:0000037) | 2.08987415 |
| 56 | X-linked dominant inheritance (HP:0001423) | 2.08961926 |
| 57 | Hypoplasia of the pons (HP:0012110) | 2.06467597 |
| 58 | Sclerocornea (HP:0000647) | 2.05851794 |
| 59 | Aplastic anemia (HP:0001915) | 2.04426574 |
| 60 | Gait imbalance (HP:0002141) | 2.02159418 |
| 61 | Exertional dyspnea (HP:0002875) | 2.01284624 |
| 62 | IgG deficiency (HP:0004315) | 2.00636403 |
| 63 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.00612609 |
| 64 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.99110932 |
| 65 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.97699306 |
| 66 | Respiratory failure (HP:0002878) | 1.94462101 |
| 67 | Horseshoe kidney (HP:0000085) | 1.92418330 |
| 68 | Lethargy (HP:0001254) | 1.91864506 |
| 69 | Delayed CNS myelination (HP:0002188) | 1.90338103 |
| 70 | Polyuria (HP:0000103) | 1.87619222 |
| 71 | Pendular nystagmus (HP:0012043) | 1.87101150 |
| 72 | Exercise intolerance (HP:0003546) | 1.85574321 |
| 73 | Congenital primary aphakia (HP:0007707) | 1.83128601 |
| 74 | Abnormality of alanine metabolism (HP:0010916) | 1.82501235 |
| 75 | Hyperalaninemia (HP:0003348) | 1.82501235 |
| 76 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.82501235 |
| 77 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 1.81109556 |
| 78 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.80575520 |
| 79 | Asplenia (HP:0001746) | 1.77753440 |
| 80 | Anencephaly (HP:0002323) | 1.74695742 |
| 81 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.74357921 |
| 82 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.73841482 |
| 83 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.73841482 |
| 84 | Lissencephaly (HP:0001339) | 1.72336772 |
| 85 | Abolished electroretinogram (ERG) (HP:0000550) | 1.71820666 |
| 86 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.71770113 |
| 87 | Constricted visual fields (HP:0001133) | 1.70620447 |
| 88 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.69994506 |
| 89 | Pallor (HP:0000980) | 1.69716477 |
| 90 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.69474614 |
| 91 | Abnormality of the renal collecting system (HP:0004742) | 1.69233143 |
| 92 | Duplicated collecting system (HP:0000081) | 1.67727740 |
| 93 | Patellar aplasia (HP:0006443) | 1.67397806 |
| 94 | Depressed nasal ridge (HP:0000457) | 1.65690155 |
| 95 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.64669813 |
| 96 | Pachygyria (HP:0001302) | 1.64407105 |
| 97 | Increased muscle lipid content (HP:0009058) | 1.63324223 |
| 98 | Oral leukoplakia (HP:0002745) | 1.62334765 |
| 99 | Aganglionic megacolon (HP:0002251) | 1.61174654 |
| 100 | Cleft eyelid (HP:0000625) | 1.60497093 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 3.41965319 |
| 2 | MAP4K2 | 3.08639845 |
| 3 | WNK4 | 3.00765463 |
| 4 | SRPK1 | 2.89794676 |
| 5 | VRK2 | 2.64372880 |
| 6 | ZAK | 2.50283453 |
| 7 | TLK1 | 2.48141125 |
| 8 | TAOK3 | 2.34297847 |
| 9 | ADRBK2 | 2.19168962 |
| 10 | STK39 | 2.07470958 |
| 11 | STK16 | 2.03998174 |
| 12 | NUAK1 | 1.96794236 |
| 13 | BCKDK | 1.91274580 |
| 14 | BCR | 1.85977160 |
| 15 | WNK3 | 1.81815271 |
| 16 | LIMK1 | 1.65344047 |
| 17 | NME1 | 1.63579118 |
| 18 | CDK8 | 1.62754772 |
| 19 | EPHA4 | 1.61121688 |
| 20 | GRK1 | 1.54778981 |
| 21 | DYRK2 | 1.49588679 |
| 22 | CAMKK2 | 1.44581370 |
| 23 | VRK1 | 1.33069657 |
| 24 | CDC7 | 1.29878356 |
| 25 | MAPK13 | 1.23298905 |
| 26 | PINK1 | 1.22205683 |
| 27 | EPHB2 | 1.19970502 |
| 28 | OXSR1 | 1.19699508 |
| 29 | TRIM28 | 1.14690663 |
| 30 | FRK | 1.09639560 |
| 31 | NEK1 | 1.05447744 |
| 32 | PLK3 | 1.04507117 |
| 33 | WEE1 | 1.03424289 |
| 34 | MAP2K7 | 1.02083990 |
| 35 | PIK3CA | 0.99526032 |
| 36 | TSSK6 | 0.97633210 |
| 37 | MAP3K11 | 0.94452000 |
| 38 | CCNB1 | 0.93461298 |
| 39 | MAP2K6 | 0.92696959 |
| 40 | PIM2 | 0.92375182 |
| 41 | DAPK2 | 0.92000965 |
| 42 | PLK4 | 0.90977979 |
| 43 | MAP3K4 | 0.90253504 |
| 44 | EIF2AK2 | 0.89973804 |
| 45 | MARK1 | 0.88453871 |
| 46 | PAK3 | 0.87719459 |
| 47 | EIF2AK3 | 0.86518071 |
| 48 | PRKCG | 0.86310417 |
| 49 | MKNK2 | 0.85963512 |
| 50 | ATR | 0.85928080 |
| 51 | PLK2 | 0.84749640 |
| 52 | PHKG2 | 0.83641672 |
| 53 | PHKG1 | 0.83641672 |
| 54 | MUSK | 0.83193491 |
| 55 | EIF2AK1 | 0.82936657 |
| 56 | PAK6 | 0.81212763 |
| 57 | KDR | 0.79411638 |
| 58 | CSNK1G3 | 0.79254064 |
| 59 | BMPR1B | 0.78530306 |
| 60 | TIE1 | 0.77958860 |
| 61 | BUB1 | 0.77817349 |
| 62 | TESK2 | 0.75824320 |
| 63 | MINK1 | 0.74900437 |
| 64 | PLK1 | 0.73553122 |
| 65 | TAF1 | 0.70500872 |
| 66 | TESK1 | 0.69848169 |
| 67 | LRRK2 | 0.68377820 |
| 68 | TNIK | 0.67337805 |
| 69 | CAMKK1 | 0.66253021 |
| 70 | CAMK1 | 0.65063353 |
| 71 | CHEK2 | 0.63950248 |
| 72 | PASK | 0.63503487 |
| 73 | CSNK1A1L | 0.62451294 |
| 74 | AURKB | 0.60920895 |
| 75 | INSRR | 0.60286318 |
| 76 | MKNK1 | 0.59258494 |
| 77 | MAP3K12 | 0.56949644 |
| 78 | CSNK1G2 | 0.56768866 |
| 79 | MAPKAPK3 | 0.56759644 |
| 80 | NTRK2 | 0.56412061 |
| 81 | GRK7 | 0.55825829 |
| 82 | CSNK1G1 | 0.55616071 |
| 83 | CSNK1E | 0.53129094 |
| 84 | CSNK2A2 | 0.53118384 |
| 85 | PNCK | 0.52791391 |
| 86 | PRKCQ | 0.51827937 |
| 87 | CSNK2A1 | 0.51695080 |
| 88 | PDK2 | 0.51611359 |
| 89 | MARK3 | 0.51257218 |
| 90 | RPS6KA5 | 0.49561892 |
| 91 | AURKA | 0.49350264 |
| 92 | RPS6KA4 | 0.48671232 |
| 93 | CAMK2A | 0.48454680 |
| 94 | DAPK3 | 0.48273083 |
| 95 | MST4 | 0.47546530 |
| 96 | SYK | 0.47492742 |
| 97 | BRSK1 | 0.46991127 |
| 98 | CSNK1A1 | 0.46921175 |
| 99 | CDK14 | 0.46528476 |
| 100 | PRKACA | 0.40682837 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.87646687 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.02709710 |
| 3 | Ribosome_Homo sapiens_hsa03010 | 3.65098496 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.30376203 |
| 5 | Protein export_Homo sapiens_hsa03060 | 3.11963298 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.99774885 |
| 7 | Mismatch repair_Homo sapiens_hsa03430 | 2.47519496 |
| 8 | Huntingtons disease_Homo sapiens_hsa05016 | 2.31508278 |
| 9 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.20321921 |
| 10 | Alzheimers disease_Homo sapiens_hsa05010 | 2.19316928 |
| 11 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.13492975 |
| 12 | Homologous recombination_Homo sapiens_hsa03440 | 2.07144996 |
| 13 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.00429430 |
| 14 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.96657386 |
| 15 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.88727339 |
| 16 | RNA degradation_Homo sapiens_hsa03018 | 1.73214306 |
| 17 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.68955389 |
| 18 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.67801077 |
| 19 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.66798127 |
| 20 | Phototransduction_Homo sapiens_hsa04744 | 1.65090768 |
| 21 | DNA replication_Homo sapiens_hsa03030 | 1.60791097 |
| 22 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.60489222 |
| 23 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.55765318 |
| 24 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.52274353 |
| 25 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.48579915 |
| 26 | Asthma_Homo sapiens_hsa05310 | 1.42612021 |
| 27 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.41651169 |
| 28 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.37389841 |
| 29 | Spliceosome_Homo sapiens_hsa03040 | 1.37126680 |
| 30 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.30820991 |
| 31 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.28787900 |
| 32 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.27224221 |
| 33 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.25324533 |
| 34 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.24924607 |
| 35 | Base excision repair_Homo sapiens_hsa03410 | 1.19548113 |
| 36 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.14722717 |
| 37 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.13821242 |
| 38 | Allograft rejection_Homo sapiens_hsa05330 | 1.10216636 |
| 39 | Basal transcription factors_Homo sapiens_hsa03022 | 1.09762644 |
| 40 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.07279947 |
| 41 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.07231823 |
| 42 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.99751511 |
| 43 | Purine metabolism_Homo sapiens_hsa00230 | 0.97652929 |
| 44 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.93660770 |
| 45 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.89500936 |
| 46 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.89472401 |
| 47 | Peroxisome_Homo sapiens_hsa04146 | 0.86879437 |
| 48 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.84287825 |
| 49 | RNA transport_Homo sapiens_hsa03013 | 0.84271494 |
| 50 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.84071744 |
| 51 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.80352942 |
| 52 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.78793165 |
| 53 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.78103938 |
| 54 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.76164177 |
| 55 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.74590566 |
| 56 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.72547450 |
| 57 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.65699744 |
| 58 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.64421224 |
| 59 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.63841856 |
| 60 | Nicotine addiction_Homo sapiens_hsa05033 | 0.63425590 |
| 61 | Metabolic pathways_Homo sapiens_hsa01100 | 0.63041189 |
| 62 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.58932473 |
| 63 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.56585992 |
| 64 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.54901407 |
| 65 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.53925093 |
| 66 | Sulfur relay system_Homo sapiens_hsa04122 | 0.53193849 |
| 67 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.50391348 |
| 68 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.49373507 |
| 69 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.48967372 |
| 70 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.48168767 |
| 71 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.46873371 |
| 72 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.42488925 |
| 73 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.42060626 |
| 74 | Olfactory transduction_Homo sapiens_hsa04740 | 0.41546681 |
| 75 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.40559430 |
| 76 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.40478503 |
| 77 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.39000260 |
| 78 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.38612545 |
| 79 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.38006425 |
| 80 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.37028193 |
| 81 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.34494678 |
| 82 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.33790242 |
| 83 | Morphine addiction_Homo sapiens_hsa05032 | 0.32213713 |
| 84 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.32156343 |
| 85 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.30681986 |
| 86 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.30537449 |
| 87 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.29724263 |
| 88 | Retinol metabolism_Homo sapiens_hsa00830 | 0.29286416 |
| 89 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.27321869 |
| 90 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.25885318 |
| 91 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.23508427 |
| 92 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.22176117 |
| 93 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.21359780 |
| 94 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.21287357 |
| 95 | Taste transduction_Homo sapiens_hsa04742 | 0.19085011 |
| 96 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.19048558 |
| 97 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.17925979 |
| 98 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.17242277 |
| 99 | GABAergic synapse_Homo sapiens_hsa04727 | 0.16205046 |
| 100 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.15924632 |

