

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | maturation of SSU-rRNA (GO:0030490) | 6.90999293 |
| 2 | ribosomal small subunit assembly (GO:0000028) | 6.28492255 |
| 3 | response to gravity (GO:0009629) | 5.68329136 |
| 4 | chaperone-mediated protein transport (GO:0072321) | 5.41659475 |
| 5 | ATP synthesis coupled proton transport (GO:0015986) | 4.76533371 |
| 6 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.76533371 |
| 7 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.76063927 |
| 8 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.75368916 |
| 9 | protein neddylation (GO:0045116) | 4.67415899 |
| 10 | DNA replication checkpoint (GO:0000076) | 4.58120010 |
| 11 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 4.37461157 |
| 12 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 4.28386126 |
| 13 | negative regulation of ligase activity (GO:0051352) | 4.28386126 |
| 14 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.28252846 |
| 15 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 4.25956083 |
| 16 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 4.23674295 |
| 17 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 4.23274978 |
| 18 | mannosylation (GO:0097502) | 4.19677681 |
| 19 | viral transcription (GO:0019083) | 4.18379809 |
| 20 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 4.12102432 |
| 21 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 4.12102432 |
| 22 | protein maturation by protein folding (GO:0022417) | 4.11897785 |
| 23 | dolichol-linked oligosaccharide biosynthetic process (GO:0006488) | 4.07024364 |
| 24 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 4.04941447 |
| 25 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 4.04929659 |
| 26 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 4.04929659 |
| 27 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 4.04929659 |
| 28 | translational termination (GO:0006415) | 4.00536903 |
| 29 | ribosomal small subunit biogenesis (GO:0042274) | 3.99518566 |
| 30 | sequestering of actin monomers (GO:0042989) | 3.97968770 |
| 31 | cotranslational protein targeting to membrane (GO:0006613) | 3.86841150 |
| 32 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.84898808 |
| 33 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.84898808 |
| 34 | glomerular visceral epithelial cell development (GO:0072015) | 3.84837490 |
| 35 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.82459922 |
| 36 | translational elongation (GO:0006414) | 3.82177074 |
| 37 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.81603695 |
| 38 | galactose catabolic process (GO:0019388) | 3.81407176 |
| 39 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.78170066 |
| 40 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 3.77757534 |
| 41 | negative regulation of telomere maintenance (GO:0032205) | 3.76610889 |
| 42 | respiratory electron transport chain (GO:0022904) | 3.72388386 |
| 43 | protein targeting to ER (GO:0045047) | 3.72032643 |
| 44 | electron transport chain (GO:0022900) | 3.71402479 |
| 45 | GDP-mannose metabolic process (GO:0019673) | 3.68556039 |
| 46 | rRNA catabolic process (GO:0016075) | 3.67666065 |
| 47 | DNA deamination (GO:0045006) | 3.67617334 |
| 48 | protein localization to endoplasmic reticulum (GO:0070972) | 3.58533410 |
| 49 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.57476714 |
| 50 | cullin deneddylation (GO:0010388) | 3.54617674 |
| 51 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.52318133 |
| 52 | cellular response to ATP (GO:0071318) | 3.51790234 |
| 53 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 3.45528200 |
| 54 | protein K63-linked deubiquitination (GO:0070536) | 3.44902505 |
| 55 | response to interferon-beta (GO:0035456) | 3.39801490 |
| 56 | maturation of 5.8S rRNA (GO:0000460) | 3.39416911 |
| 57 | resolution of meiotic recombination intermediates (GO:0000712) | 3.37948112 |
| 58 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.37839879 |
| 59 | positive regulation of ligase activity (GO:0051351) | 3.35216879 |
| 60 | glomerular epithelial cell development (GO:0072310) | 3.34144989 |
| 61 | protein complex biogenesis (GO:0070271) | 3.33676322 |
| 62 | regulation of mitochondrial translation (GO:0070129) | 3.32371873 |
| 63 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.30475563 |
| 64 | translation (GO:0006412) | 3.26960801 |
| 65 | protein deneddylation (GO:0000338) | 3.22766846 |
| 66 | positive regulation of cell cycle arrest (GO:0071158) | 3.21848138 |
| 67 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 3.19219870 |
| 68 | viral mRNA export from host cell nucleus (GO:0046784) | 3.16890840 |
| 69 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.15568021 |
| 70 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.14213480 |
| 71 | viral life cycle (GO:0019058) | 3.11697482 |
| 72 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.09550899 |
| 73 | regulation of cellular amine metabolic process (GO:0033238) | 3.09252081 |
| 74 | cellular protein complex disassembly (GO:0043624) | 3.07968505 |
| 75 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.06419664 |
| 76 | establishment of viral latency (GO:0019043) | 3.06145238 |
| 77 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 3.05007978 |
| 78 | ncRNA catabolic process (GO:0034661) | 3.02628219 |
| 79 | translational initiation (GO:0006413) | 2.96527043 |
| 80 | DNA strand elongation (GO:0022616) | 2.95396724 |
| 81 | skeletal muscle tissue regeneration (GO:0043403) | 2.94852545 |
| 82 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.92572466 |
| 83 | negative regulation of protein ubiquitination (GO:0031397) | 2.90963972 |
| 84 | cellular response to interferon-beta (GO:0035458) | 2.90503991 |
| 85 | regulation of cell cycle arrest (GO:0071156) | 2.89620308 |
| 86 | GTP biosynthetic process (GO:0006183) | 2.89559862 |
| 87 | pattern specification involved in kidney development (GO:0061004) | 2.89451307 |
| 88 | regulation of ligase activity (GO:0051340) | 2.88528527 |
| 89 | signal transduction in response to DNA damage (GO:0042770) | 2.88003360 |
| 90 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.87477724 |
| 91 | NADH dehydrogenase complex assembly (GO:0010257) | 2.87477724 |
| 92 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.87477724 |
| 93 | detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) | 2.83008307 |
| 94 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.81143197 |
| 95 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.81143197 |
| 96 | peroxisome fission (GO:0016559) | 2.80744603 |
| 97 | telencephalon development (GO:0021537) | 2.78989032 |
| 98 | transcription-coupled nucleotide-excision repair (GO:0006283) | 2.77097147 |
| 99 | proteasome assembly (GO:0043248) | 2.76447022 |
| 100 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.74455598 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 5.19030059 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.15624420 |
| 3 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.12398148 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.00510824 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.85844295 |
| 6 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 3.85170978 |
| 7 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.63526520 |
| 8 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.61936898 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.38604341 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.00945269 |
| 11 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.96871655 |
| 12 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.96502205 |
| 13 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.78625063 |
| 14 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.76295939 |
| 15 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.71923579 |
| 16 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.71124555 |
| 17 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.67886797 |
| 18 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.55792324 |
| 19 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.53009303 |
| 20 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.45865211 |
| 21 | VDR_22108803_ChIP-Seq_LS180_Human | 2.42710677 |
| 22 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.38305674 |
| 23 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.34206543 |
| 24 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.29695212 |
| 25 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.15618686 |
| 26 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.11200129 |
| 27 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.10454101 |
| 28 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.02913623 |
| 29 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.00867171 |
| 30 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.90504215 |
| 31 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.88655389 |
| 32 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.84183282 |
| 33 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.78703971 |
| 34 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.72687151 |
| 35 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.71238087 |
| 36 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.68469393 |
| 37 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.68027813 |
| 38 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.67762649 |
| 39 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.67762649 |
| 40 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.67762649 |
| 41 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.67599956 |
| 42 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.67411104 |
| 43 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.59644908 |
| 44 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.58879500 |
| 45 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.58090304 |
| 46 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.53052350 |
| 47 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.50979894 |
| 48 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.49445256 |
| 49 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.48119606 |
| 50 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.39559868 |
| 51 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.35256460 |
| 52 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.35146042 |
| 53 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.35068864 |
| 54 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.32859040 |
| 55 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.30428732 |
| 56 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.26904242 |
| 57 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.23940957 |
| 58 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.22530883 |
| 59 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.21425582 |
| 60 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.19260333 |
| 61 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.18702950 |
| 62 | EWS_26573619_Chip-Seq_HEK293_Human | 1.18327403 |
| 63 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.10842227 |
| 64 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.10751486 |
| 65 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.09638898 |
| 66 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.08724167 |
| 67 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.05119751 |
| 68 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.03177828 |
| 69 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.01765789 |
| 70 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.01476571 |
| 71 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.98726271 |
| 72 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.97476147 |
| 73 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.96777940 |
| 74 | AR_20517297_ChIP-Seq_VCAP_Human | 0.95189162 |
| 75 | CBP_21632823_ChIP-Seq_H3396_Human | 0.93312460 |
| 76 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.92019737 |
| 77 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.90475454 |
| 78 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.89405314 |
| 79 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.89341944 |
| 80 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.89269261 |
| 81 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.89088243 |
| 82 | EOMES_21245162_ChIP-Seq_HESCs_Human | 0.88264284 |
| 83 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.88163923 |
| 84 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.88077762 |
| 85 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.87846112 |
| 86 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.84495016 |
| 87 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.84203770 |
| 88 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.83707113 |
| 89 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.83401754 |
| 90 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.83103326 |
| 91 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.82610404 |
| 92 | GATA3_26560356_Chip-Seq_TH2_Human | 0.81710280 |
| 93 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.81205767 |
| 94 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.80735217 |
| 95 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.79462204 |
| 96 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.78462898 |
| 97 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.78299415 |
| 98 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.77818436 |
| 99 | EZH2_22144423_ChIP-Seq_EOC_Human | 0.77707680 |
| 100 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.76966406 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003693_abnormal_embryo_hatching | 4.53357463 |
| 2 | MP0009379_abnormal_foot_pigmentation | 3.86422379 |
| 3 | MP0003123_paternal_imprinting | 3.39889562 |
| 4 | MP0002166_altered_tumor_susceptibility | 2.95500988 |
| 5 | MP0010030_abnormal_orbit_morphology | 2.80995202 |
| 6 | MP0000749_muscle_degeneration | 2.80034036 |
| 7 | MP0002006_tumorigenesis | 2.61836794 |
| 8 | MP0008875_abnormal_xenobiotic_pharmacok | 2.58864964 |
| 9 | MP0002277_abnormal_respiratory_mucosa | 2.54643843 |
| 10 | MP0005408_hypopigmentation | 2.40846983 |
| 11 | MP0004142_abnormal_muscle_tone | 2.38576383 |
| 12 | MP0003786_premature_aging | 2.38420527 |
| 13 | MP0006292_abnormal_olfactory_placode | 2.15776455 |
| 14 | MP0000569_abnormal_digit_pigmentation | 2.15348082 |
| 15 | MP0008007_abnormal_cellular_replicative | 2.05132799 |
| 16 | MP0003045_fibrosis | 2.03600163 |
| 17 | MP0001905_abnormal_dopamine_level | 1.93193554 |
| 18 | MP0010094_abnormal_chromosome_stability | 1.88891958 |
| 19 | MP0006072_abnormal_retinal_apoptosis | 1.86773161 |
| 20 | MP0008775_abnormal_heart_ventricle | 1.79896275 |
| 21 | MP0002837_dystrophic_cardiac_calcinosis | 1.73125285 |
| 22 | MP0005367_renal/urinary_system_phenotyp | 1.67439188 |
| 23 | MP0000516_abnormal_urinary_system | 1.67439188 |
| 24 | MP0004957_abnormal_blastocyst_morpholog | 1.66752937 |
| 25 | MP0000747_muscle_weakness | 1.66095977 |
| 26 | MP0002938_white_spotting | 1.64954221 |
| 27 | MP0008877_abnormal_DNA_methylation | 1.64180124 |
| 28 | MP0001243_abnormal_dermal_layer | 1.64032076 |
| 29 | MP0003890_abnormal_embryonic-extraembry | 1.58736711 |
| 30 | MP0002095_abnormal_skin_pigmentation | 1.48601272 |
| 31 | MP0005083_abnormal_biliary_tract | 1.46010923 |
| 32 | MP0001293_anophthalmia | 1.45865614 |
| 33 | MP0004147_increased_porphyrin_level | 1.40216488 |
| 34 | MP0008058_abnormal_DNA_repair | 1.39392187 |
| 35 | MP0001485_abnormal_pinna_reflex | 1.38369395 |
| 36 | MP0003938_abnormal_ear_development | 1.36116424 |
| 37 | MP0003121_genomic_imprinting | 1.35796482 |
| 38 | MP0003646_muscle_fatigue | 1.35058784 |
| 39 | MP0002736_abnormal_nociception_after | 1.26365727 |
| 40 | MP0000566_synostosis | 1.21650641 |
| 41 | MP0001542_abnormal_bone_strength | 1.19306016 |
| 42 | MP0008872_abnormal_physiological_respon | 1.19000072 |
| 43 | MP0003300_gastrointestinal_ulcer | 1.18595282 |
| 44 | MP0005671_abnormal_response_to | 1.18420791 |
| 45 | MP0002282_abnormal_trachea_morphology | 1.17299691 |
| 46 | MP0003186_abnormal_redox_activity | 1.16265720 |
| 47 | MP0004145_abnormal_muscle_electrophysio | 1.15083006 |
| 48 | MP0002638_abnormal_pupillary_reflex | 1.14684233 |
| 49 | MP0004885_abnormal_endolymph | 1.12761698 |
| 50 | MP0003567_abnormal_fetal_cardiomyocyte | 1.10941359 |
| 51 | MP0003195_calcinosis | 1.10480361 |
| 52 | MP0003315_abnormal_perineum_morphology | 1.08195348 |
| 53 | MP0000750_abnormal_muscle_regeneration | 1.05819248 |
| 54 | MP0006276_abnormal_autonomic_nervous | 1.05751978 |
| 55 | MP0003880_abnormal_central_pattern | 1.03540271 |
| 56 | MP0005084_abnormal_gallbladder_morpholo | 1.00324765 |
| 57 | MP0002210_abnormal_sex_determination | 0.97848810 |
| 58 | MP0004742_abnormal_vestibular_system | 0.97730702 |
| 59 | MP0006036_abnormal_mitochondrial_physio | 0.94817443 |
| 60 | MP0003937_abnormal_limbs/digits/tail_de | 0.93118886 |
| 61 | MP0001340_abnormal_eyelid_morphology | 0.90785012 |
| 62 | MP0000358_abnormal_cell_content/ | 0.86038040 |
| 63 | MP0005165_increased_susceptibility_to | 0.84973264 |
| 64 | MP0001764_abnormal_homeostasis | 0.84438123 |
| 65 | MP0000049_abnormal_middle_ear | 0.83516671 |
| 66 | MP0005636_abnormal_mineral_homeostasis | 0.82788760 |
| 67 | MP0003787_abnormal_imprinting | 0.79870009 |
| 68 | MP0002106_abnormal_muscle_physiology | 0.79835454 |
| 69 | MP0001919_abnormal_reproductive_system | 0.78585126 |
| 70 | MP0002109_abnormal_limb_morphology | 0.78453866 |
| 71 | MP0010368_abnormal_lymphatic_system | 0.77174352 |
| 72 | MP0000372_irregular_coat_pigmentation | 0.77136884 |
| 73 | MP0000762_abnormal_tongue_morphology | 0.74332852 |
| 74 | MP0008932_abnormal_embryonic_tissue | 0.74072570 |
| 75 | MP0002933_joint_inflammation | 0.73704725 |
| 76 | MP0002932_abnormal_joint_morphology | 0.72029153 |
| 77 | MP0005389_reproductive_system_phenotype | 0.71542393 |
| 78 | MP0006054_spinal_hemorrhage | 0.71537470 |
| 79 | MP0000631_abnormal_neuroendocrine_gland | 0.70813868 |
| 80 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.69769008 |
| 81 | MP0000653_abnormal_sex_gland | 0.69572804 |
| 82 | MP0003077_abnormal_cell_cycle | 0.69056883 |
| 83 | MP0005174_abnormal_tail_pigmentation | 0.67539170 |
| 84 | MP0003718_maternal_effect | 0.67361449 |
| 85 | MP0001119_abnormal_female_reproductive | 0.67131134 |
| 86 | MP0009333_abnormal_splenocyte_physiolog | 0.66903020 |
| 87 | MP0002733_abnormal_thermal_nociception | 0.66577911 |
| 88 | MP0009046_muscle_twitch | 0.65160460 |
| 89 | MP0002184_abnormal_innervation | 0.63917427 |
| 90 | MP0002111_abnormal_tail_morphology | 0.63581504 |
| 91 | MP0005646_abnormal_pituitary_gland | 0.63416150 |
| 92 | MP0001963_abnormal_hearing_physiology | 0.62203958 |
| 93 | MP0002653_abnormal_ependyma_morphology | 0.62000780 |
| 94 | MP0002896_abnormal_bone_mineralization | 0.61990996 |
| 95 | MP0003279_aneurysm | 0.61599425 |
| 96 | MP0001145_abnormal_male_reproductive | 0.61446310 |
| 97 | MP0002177_abnormal_outer_ear | 0.61175229 |
| 98 | MP0001765_abnormal_ion_homeostasis | 0.60859418 |
| 99 | MP0003191_abnormal_cellular_cholesterol | 0.60211940 |
| 100 | MP0005257_abnormal_intraocular_pressure | 0.58837554 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Reticulocytopenia (HP:0001896) | 4.72712611 |
| 2 | Reduced antithrombin III activity (HP:0001976) | 4.48092710 |
| 3 | Type I transferrin isoform profile (HP:0003642) | 3.82746154 |
| 4 | Methylmalonic acidemia (HP:0002912) | 3.80389665 |
| 5 | Mitochondrial inheritance (HP:0001427) | 3.67239608 |
| 6 | Oligomenorrhea (HP:0000876) | 3.64585667 |
| 7 | Methylmalonic aciduria (HP:0012120) | 3.61571877 |
| 8 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 3.56250181 |
| 9 | Adrenal hypoplasia (HP:0000835) | 3.47379302 |
| 10 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.45849681 |
| 11 | Acute necrotizing encephalopathy (HP:0006965) | 3.43845710 |
| 12 | Hepatic necrosis (HP:0002605) | 3.29479900 |
| 13 | Hepatocellular necrosis (HP:0001404) | 3.27350916 |
| 14 | Delayed CNS myelination (HP:0002188) | 3.21272471 |
| 15 | Increased CSF lactate (HP:0002490) | 3.20123100 |
| 16 | Hypoproteinemia (HP:0003075) | 3.15336130 |
| 17 | Abnormal protein glycosylation (HP:0012346) | 3.05729671 |
| 18 | Abnormal glycosylation (HP:0012345) | 3.05729671 |
| 19 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 3.05729671 |
| 20 | Abnormal protein N-linked glycosylation (HP:0012347) | 3.05729671 |
| 21 | Stenosis of the external auditory canal (HP:0000402) | 3.04153694 |
| 22 | Abnormality of DNA repair (HP:0003254) | 3.03218991 |
| 23 | Hypoplasia of the pons (HP:0012110) | 2.99239410 |
| 24 | Abnormality of the pons (HP:0007361) | 2.82601809 |
| 25 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.81566221 |
| 26 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.81566221 |
| 27 | Progressive macrocephaly (HP:0004481) | 2.79396740 |
| 28 | Dicarboxylic aciduria (HP:0003215) | 2.78586540 |
| 29 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.78586540 |
| 30 | Absent thumb (HP:0009777) | 2.73269147 |
| 31 | Exercise intolerance (HP:0003546) | 2.69062750 |
| 32 | Decreased subcutaneous fat (HP:0001002) | 2.68244046 |
| 33 | Abnormality of the renal cortex (HP:0011035) | 2.65839079 |
| 34 | Increased intramyocellular lipid droplets (HP:0012240) | 2.64972946 |
| 35 | Meckel diverticulum (HP:0002245) | 2.57910345 |
| 36 | Acute encephalopathy (HP:0006846) | 2.57379897 |
| 37 | Renal cortical cysts (HP:0000803) | 2.55295229 |
| 38 | Cerebral palsy (HP:0100021) | 2.54672108 |
| 39 | Colon cancer (HP:0003003) | 2.51009035 |
| 40 | Abnormality of the ileum (HP:0001549) | 2.50770774 |
| 41 | Palpitations (HP:0001962) | 2.49626221 |
| 42 | Increased hepatocellular lipid droplets (HP:0006565) | 2.49353827 |
| 43 | Palpebral edema (HP:0100540) | 2.45811973 |
| 44 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.43524935 |
| 45 | Myopathic facies (HP:0002058) | 2.41636104 |
| 46 | Chromsome breakage (HP:0040012) | 2.40418119 |
| 47 | Lipid accumulation in hepatocytes (HP:0006561) | 2.37196504 |
| 48 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.36284471 |
| 49 | Congenital, generalized hypertrichosis (HP:0004540) | 2.30233153 |
| 50 | Flat capital femoral epiphysis (HP:0003370) | 2.30093250 |
| 51 | Abnormality of the preputium (HP:0100587) | 2.29744293 |
| 52 | Hypochromic microcytic anemia (HP:0004840) | 2.29743908 |
| 53 | Pancreatic cysts (HP:0001737) | 2.26946551 |
| 54 | Septo-optic dysplasia (HP:0100842) | 2.24820904 |
| 55 | Abnormality of chromosome stability (HP:0003220) | 2.23080311 |
| 56 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.22781001 |
| 57 | Pendular nystagmus (HP:0012043) | 2.20743597 |
| 58 | Myotonia (HP:0002486) | 2.19375008 |
| 59 | Increased muscle lipid content (HP:0009058) | 2.18295851 |
| 60 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.14917043 |
| 61 | CNS demyelination (HP:0007305) | 2.13639447 |
| 62 | Exertional dyspnea (HP:0002875) | 2.12424770 |
| 63 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.11577336 |
| 64 | Increased serum lactate (HP:0002151) | 2.10642528 |
| 65 | Lactic acidosis (HP:0003128) | 2.09436551 |
| 66 | Respiratory failure (HP:0002878) | 2.06738468 |
| 67 | Macrocytic anemia (HP:0001972) | 2.05568100 |
| 68 | Microglossia (HP:0000171) | 2.05291750 |
| 69 | Opisthotonus (HP:0002179) | 2.04334415 |
| 70 | Ketosis (HP:0001946) | 2.03168649 |
| 71 | Asplenia (HP:0001746) | 2.00201045 |
| 72 | Sclerocornea (HP:0000647) | 1.96525352 |
| 73 | Esophageal atresia (HP:0002032) | 1.95288844 |
| 74 | Supernumerary spleens (HP:0009799) | 1.94179248 |
| 75 | Cerebral edema (HP:0002181) | 1.93490365 |
| 76 | Abnormality of vitamin B metabolism (HP:0004340) | 1.93195728 |
| 77 | Delayed gross motor development (HP:0002194) | 1.92927459 |
| 78 | Renal Fanconi syndrome (HP:0001994) | 1.91590286 |
| 79 | Reduced subcutaneous adipose tissue (HP:0003758) | 1.90666261 |
| 80 | Pancreatic fibrosis (HP:0100732) | 1.90055957 |
| 81 | Abnormal pupillary function (HP:0007686) | 1.89373435 |
| 82 | Entropion (HP:0000621) | 1.89181595 |
| 83 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.88950223 |
| 84 | Absent phalangeal crease (HP:0006109) | 1.85591300 |
| 85 | Neuroendocrine neoplasm (HP:0100634) | 1.83642587 |
| 86 | Clubbing of toes (HP:0100760) | 1.83629943 |
| 87 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.83481248 |
| 88 | Maternal diabetes (HP:0009800) | 1.83426388 |
| 89 | Aplastic anemia (HP:0001915) | 1.83426146 |
| 90 | Absent speech (HP:0001344) | 1.79508849 |
| 91 | 11 pairs of ribs (HP:0000878) | 1.74105342 |
| 92 | Upper limb muscle weakness (HP:0003484) | 1.73754285 |
| 93 | Myoglobinuria (HP:0002913) | 1.72166713 |
| 94 | Small intestinal stenosis (HP:0012848) | 1.72113356 |
| 95 | Duodenal stenosis (HP:0100867) | 1.72113356 |
| 96 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.71635552 |
| 97 | Muscle stiffness (HP:0003552) | 1.69431404 |
| 98 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.69018240 |
| 99 | Pancytopenia (HP:0001876) | 1.67568171 |
| 100 | Carpal bone hypoplasia (HP:0001498) | 1.65097563 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 5.05591802 |
| 2 | STK16 | 4.11780644 |
| 3 | TESK2 | 3.90772839 |
| 4 | LIMK1 | 3.67516920 |
| 5 | TESK1 | 3.19698149 |
| 6 | TXK | 2.46121847 |
| 7 | BUB1 | 2.37092532 |
| 8 | NME2 | 2.34812749 |
| 9 | TAF1 | 2.33415649 |
| 10 | NEK9 | 2.31798234 |
| 11 | MAP4K2 | 2.28773789 |
| 12 | SRPK1 | 2.21178341 |
| 13 | MAP3K12 | 2.20091666 |
| 14 | VRK1 | 2.03877056 |
| 15 | EIF2AK3 | 1.98928569 |
| 16 | PHKG1 | 1.90980913 |
| 17 | PHKG2 | 1.90980913 |
| 18 | TLK1 | 1.84935603 |
| 19 | MST4 | 1.79763221 |
| 20 | KDR | 1.72053015 |
| 21 | TAOK3 | 1.57656925 |
| 22 | DAPK1 | 1.41823588 |
| 23 | CCNB1 | 1.40139148 |
| 24 | BCKDK | 1.40037783 |
| 25 | EIF2AK1 | 1.39492426 |
| 26 | MAP3K6 | 1.30992273 |
| 27 | PLK4 | 1.30226558 |
| 28 | EPHA4 | 1.25690992 |
| 29 | TIE1 | 1.24761061 |
| 30 | NUAK1 | 1.24237867 |
| 31 | AURKA | 1.23377161 |
| 32 | CLK1 | 1.16008158 |
| 33 | WNK3 | 1.10877916 |
| 34 | CDC7 | 1.04812251 |
| 35 | DYRK2 | 1.03589087 |
| 36 | CSNK1G3 | 0.95593528 |
| 37 | WNK4 | 0.94710961 |
| 38 | MAP2K7 | 0.93801086 |
| 39 | GRK1 | 0.90930428 |
| 40 | MAP3K11 | 0.90852791 |
| 41 | SCYL2 | 0.87249782 |
| 42 | ZAP70 | 0.87018076 |
| 43 | IKBKE | 0.86886442 |
| 44 | OBSCN | 0.84664295 |
| 45 | PIM2 | 0.82535438 |
| 46 | AURKB | 0.80934739 |
| 47 | OXSR1 | 0.80555803 |
| 48 | CAMKK2 | 0.80182321 |
| 49 | ATR | 0.79874334 |
| 50 | ARAF | 0.79866797 |
| 51 | STK39 | 0.78617874 |
| 52 | CSNK1G2 | 0.78073971 |
| 53 | MAP4K1 | 0.74987894 |
| 54 | CSNK1A1L | 0.73756744 |
| 55 | RPS6KA5 | 0.73612690 |
| 56 | DAPK3 | 0.71644392 |
| 57 | EIF2AK2 | 0.71361541 |
| 58 | TNK2 | 0.71264602 |
| 59 | ABL2 | 0.69469587 |
| 60 | EPHA2 | 0.69402274 |
| 61 | PLK3 | 0.67985974 |
| 62 | UHMK1 | 0.67092047 |
| 63 | PLK2 | 0.66992696 |
| 64 | LRRK2 | 0.65827463 |
| 65 | CSNK1G1 | 0.63638325 |
| 66 | PLK1 | 0.58340503 |
| 67 | MAP2K4 | 0.54769614 |
| 68 | CHEK2 | 0.52455800 |
| 69 | PRKCE | 0.51183068 |
| 70 | PDK2 | 0.50669458 |
| 71 | LMTK2 | 0.48329421 |
| 72 | ADRBK2 | 0.45861261 |
| 73 | DAPK2 | 0.45751300 |
| 74 | ERBB4 | 0.44448063 |
| 75 | PRKCI | 0.43114558 |
| 76 | GRK5 | 0.42780025 |
| 77 | MYLK | 0.42698997 |
| 78 | NME1 | 0.41998389 |
| 79 | CSNK1A1 | 0.40560603 |
| 80 | CSNK2A2 | 0.38610395 |
| 81 | NEK1 | 0.37801512 |
| 82 | INSRR | 0.37099467 |
| 83 | EPHB2 | 0.35830640 |
| 84 | FRK | 0.35216709 |
| 85 | GRK6 | 0.33594848 |
| 86 | PIM1 | 0.30997903 |
| 87 | MKNK2 | 0.30175889 |
| 88 | PRKCQ | 0.30131722 |
| 89 | BRSK1 | 0.30038025 |
| 90 | MAP2K2 | 0.29753613 |
| 91 | BRAF | 0.29503310 |
| 92 | CSNK2A1 | 0.29111836 |
| 93 | MATK | 0.27574615 |
| 94 | PAK1 | 0.27361769 |
| 95 | PTK6 | 0.27178071 |
| 96 | MINK1 | 0.26936435 |
| 97 | STK10 | 0.26245139 |
| 98 | PTK2B | 0.26224296 |
| 99 | TNIK | 0.24879254 |
| 100 | PRKACA | 0.24576309 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.80477773 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 4.22257099 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.82977332 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.45247434 |
| 5 | DNA replication_Homo sapiens_hsa03030 | 3.15618885 |
| 6 | Mismatch repair_Homo sapiens_hsa03430 | 2.68008265 |
| 7 | Huntingtons disease_Homo sapiens_hsa05016 | 2.46238389 |
| 8 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.43509394 |
| 9 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.37120383 |
| 10 | Alzheimers disease_Homo sapiens_hsa05010 | 2.35346736 |
| 11 | Homologous recombination_Homo sapiens_hsa03440 | 2.34228518 |
| 12 | RNA polymerase_Homo sapiens_hsa03020 | 2.06558606 |
| 13 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.01016300 |
| 14 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.98111353 |
| 15 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.94949844 |
| 16 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.75628309 |
| 17 | Spliceosome_Homo sapiens_hsa03040 | 1.72428726 |
| 18 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.67786738 |
| 19 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.64807959 |
| 20 | Protein export_Homo sapiens_hsa03060 | 1.59281243 |
| 21 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.54846353 |
| 22 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.53533904 |
| 23 | RNA transport_Homo sapiens_hsa03013 | 1.52737218 |
| 24 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.47875133 |
| 25 | Base excision repair_Homo sapiens_hsa03410 | 1.37494737 |
| 26 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.32537306 |
| 27 | RNA degradation_Homo sapiens_hsa03018 | 1.25745060 |
| 28 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.24576602 |
| 29 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.22334187 |
| 30 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.16355678 |
| 31 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.15585298 |
| 32 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.12475635 |
| 33 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.12174471 |
| 34 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.11535927 |
| 35 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.10108575 |
| 36 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.08267644 |
| 37 | Basal transcription factors_Homo sapiens_hsa03022 | 1.07545758 |
| 38 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.06995999 |
| 39 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.01646999 |
| 40 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.99649422 |
| 41 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.89788040 |
| 42 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.89141992 |
| 43 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.88145999 |
| 44 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.85656098 |
| 45 | Histidine metabolism_Homo sapiens_hsa00340 | 0.85589360 |
| 46 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.83661378 |
| 47 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.74513646 |
| 48 | Galactose metabolism_Homo sapiens_hsa00052 | 0.73755160 |
| 49 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.73331418 |
| 50 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.72039068 |
| 51 | Purine metabolism_Homo sapiens_hsa00230 | 0.71164244 |
| 52 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.70955101 |
| 53 | Peroxisome_Homo sapiens_hsa04146 | 0.70133592 |
| 54 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.69147079 |
| 55 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.66570526 |
| 56 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.66420436 |
| 57 | Metabolic pathways_Homo sapiens_hsa01100 | 0.64291693 |
| 58 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.63637617 |
| 59 | Cell cycle_Homo sapiens_hsa04110 | 0.63549750 |
| 60 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.59051429 |
| 61 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.57919940 |
| 62 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.54227637 |
| 63 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.49146996 |
| 64 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.48513736 |
| 65 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.47818964 |
| 66 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.46857403 |
| 67 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.46618811 |
| 68 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.46376895 |
| 69 | Salivary secretion_Homo sapiens_hsa04970 | 0.45916754 |
| 70 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.45744388 |
| 71 | Carbon metabolism_Homo sapiens_hsa01200 | 0.40877048 |
| 72 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.40298069 |
| 73 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.37975617 |
| 74 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.37019224 |
| 75 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.36549991 |
| 76 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.36246537 |
| 77 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.34201603 |
| 78 | Sulfur relay system_Homo sapiens_hsa04122 | 0.33912383 |
| 79 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.32689344 |
| 80 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.31030158 |
| 81 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.29515791 |
| 82 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.29440604 |
| 83 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.28643328 |
| 84 | Phototransduction_Homo sapiens_hsa04744 | 0.25101356 |
| 85 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.23965413 |
| 86 | Retinol metabolism_Homo sapiens_hsa00830 | 0.22694879 |
| 87 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.22539130 |
| 88 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.22399144 |
| 89 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.22069395 |
| 90 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.21874432 |
| 91 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.20930133 |
| 92 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.19090121 |
| 93 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.18918125 |
| 94 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.18078890 |
| 95 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.17158506 |
| 96 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.16040836 |
| 97 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.15633145 |
| 98 | Tight junction_Homo sapiens_hsa04530 | 0.15415119 |
| 99 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.12780889 |
| 100 | Lysine degradation_Homo sapiens_hsa00310 | 0.11457596 |

