

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | protein neddylation (GO:0045116) | 5.40646645 |
| 2 | chaperone-mediated protein transport (GO:0072321) | 4.86023811 |
| 3 | ATP synthesis coupled proton transport (GO:0015986) | 4.76421790 |
| 4 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.76421790 |
| 5 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.75598420 |
| 6 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.65143575 |
| 7 | DNA deamination (GO:0045006) | 4.58886013 |
| 8 | protein complex biogenesis (GO:0070271) | 4.29224970 |
| 9 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.27206457 |
| 10 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.27206457 |
| 11 | NADH dehydrogenase complex assembly (GO:0010257) | 4.27206457 |
| 12 | GTP biosynthetic process (GO:0006183) | 4.08392668 |
| 13 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 4.08000871 |
| 14 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.00616036 |
| 15 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.97595583 |
| 16 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.92576425 |
| 17 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.90124618 |
| 18 | maturation of SSU-rRNA (GO:0030490) | 3.85705231 |
| 19 | chromatin remodeling at centromere (GO:0031055) | 3.82070294 |
| 20 | respiratory electron transport chain (GO:0022904) | 3.67692241 |
| 21 | electron transport chain (GO:0022900) | 3.66971907 |
| 22 | DNA replication checkpoint (GO:0000076) | 3.63422311 |
| 23 | CENP-A containing nucleosome assembly (GO:0034080) | 3.58328199 |
| 24 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.58247315 |
| 25 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.56968835 |
| 26 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.48692784 |
| 27 | ribosomal small subunit assembly (GO:0000028) | 3.46092515 |
| 28 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.44985785 |
| 29 | UTP biosynthetic process (GO:0006228) | 3.44649503 |
| 30 | kinetochore organization (GO:0051383) | 3.41875830 |
| 31 | kinetochore assembly (GO:0051382) | 3.38559143 |
| 32 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.36601731 |
| 33 | UTP metabolic process (GO:0046051) | 3.28698571 |
| 34 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 3.25144136 |
| 35 | cytidine catabolic process (GO:0006216) | 3.23718167 |
| 36 | cytidine deamination (GO:0009972) | 3.23718167 |
| 37 | cytidine metabolic process (GO:0046087) | 3.23718167 |
| 38 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.22873193 |
| 39 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.21103317 |
| 40 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.18923047 |
| 41 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.17891965 |
| 42 | CTP metabolic process (GO:0046036) | 3.17063705 |
| 43 | CTP biosynthetic process (GO:0006241) | 3.17063705 |
| 44 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 3.16009372 |
| 45 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.14821295 |
| 46 | negative regulation of ligase activity (GO:0051352) | 3.14821295 |
| 47 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.13415982 |
| 48 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.11009150 |
| 49 | negative regulation of thymocyte apoptotic process (GO:0070244) | 3.10771588 |
| 50 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.07130180 |
| 51 | termination of RNA polymerase III transcription (GO:0006386) | 3.07130180 |
| 52 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.06281438 |
| 53 | resolution of meiotic recombination intermediates (GO:0000712) | 3.04407973 |
| 54 | deoxyribose phosphate catabolic process (GO:0046386) | 3.03850254 |
| 55 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.03150337 |
| 56 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.03150337 |
| 57 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.03150337 |
| 58 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.01869636 |
| 59 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.01869636 |
| 60 | DNA double-strand break processing (GO:0000729) | 3.00206404 |
| 61 | DNA strand elongation (GO:0022616) | 2.99335818 |
| 62 | deoxyribonucleotide catabolic process (GO:0009264) | 2.96723095 |
| 63 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.96547495 |
| 64 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.96547495 |
| 65 | histone exchange (GO:0043486) | 2.96547116 |
| 66 | viral transcription (GO:0019083) | 2.95729632 |
| 67 | inner mitochondrial membrane organization (GO:0007007) | 2.95681002 |
| 68 | mitotic recombination (GO:0006312) | 2.95174335 |
| 69 | DNA ligation (GO:0006266) | 2.93465471 |
| 70 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.93098841 |
| 71 | rRNA modification (GO:0000154) | 2.92834547 |
| 72 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.91397641 |
| 73 | cytochrome complex assembly (GO:0017004) | 2.90513303 |
| 74 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.90193936 |
| 75 | respiratory chain complex IV assembly (GO:0008535) | 2.89777950 |
| 76 | translational termination (GO:0006415) | 2.88017493 |
| 77 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.87802341 |
| 78 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.87802341 |
| 79 | telomere maintenance via recombination (GO:0000722) | 2.87181900 |
| 80 | cellular component biogenesis (GO:0044085) | 2.87044054 |
| 81 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.86184825 |
| 82 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 2.85973132 |
| 83 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.85587161 |
| 84 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.85100735 |
| 85 | negative regulation of telomere maintenance (GO:0032205) | 2.82210195 |
| 86 | DNA damage response, detection of DNA damage (GO:0042769) | 2.81325671 |
| 87 | ribosomal large subunit biogenesis (GO:0042273) | 2.79946916 |
| 88 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.79536953 |
| 89 | base-excision repair, AP site formation (GO:0006285) | 2.79053301 |
| 90 | replication fork processing (GO:0031297) | 2.78293212 |
| 91 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 2.77338465 |
| 92 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 2.76100806 |
| 93 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.75432860 |
| 94 | cotranslational protein targeting to membrane (GO:0006613) | 2.75177649 |
| 95 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.73034864 |
| 96 | behavioral response to nicotine (GO:0035095) | 2.72859368 |
| 97 | protein targeting to ER (GO:0045047) | 2.72230205 |
| 98 | translation (GO:0006412) | 2.70601841 |
| 99 | DNA replication-independent nucleosome organization (GO:0034724) | 2.69503675 |
| 100 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.69503675 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.63674824 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.63585138 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.42059668 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.89988899 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.83179040 |
| 6 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.75833744 |
| 7 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.21736221 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.02256488 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.98257955 |
| 10 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.83490098 |
| 11 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.77517466 |
| 12 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.73996663 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.60595320 |
| 14 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.53674081 |
| 15 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.46529827 |
| 16 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.44138475 |
| 17 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.43000789 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.25318111 |
| 19 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.23987677 |
| 20 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.09795319 |
| 21 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.96794892 |
| 22 | VDR_22108803_ChIP-Seq_LS180_Human | 1.91342064 |
| 23 | EWS_26573619_Chip-Seq_HEK293_Human | 1.88833173 |
| 24 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.83845185 |
| 25 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.80240494 |
| 26 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.79023369 |
| 27 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.73129033 |
| 28 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.72858478 |
| 29 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.71363891 |
| 30 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.66430761 |
| 31 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.66389748 |
| 32 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.63311073 |
| 33 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.52117110 |
| 34 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.51387559 |
| 35 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.49539050 |
| 36 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.49460951 |
| 37 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.49353423 |
| 38 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.49255155 |
| 39 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.46207688 |
| 40 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.40031753 |
| 41 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.34617141 |
| 42 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.34367341 |
| 43 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.33792695 |
| 44 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.32043213 |
| 45 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.32031468 |
| 46 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.30253851 |
| 47 | FUS_26573619_Chip-Seq_HEK293_Human | 1.30111353 |
| 48 | P300_19829295_ChIP-Seq_ESCs_Human | 1.27434761 |
| 49 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.24044111 |
| 50 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.22263948 |
| 51 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.21155274 |
| 52 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.20860524 |
| 53 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.16965527 |
| 54 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.13212346 |
| 55 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.11364133 |
| 56 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.09958427 |
| 57 | NCOR_22424771_ChIP-Seq_293T_Human | 1.09206057 |
| 58 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.09016645 |
| 59 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.08346074 |
| 60 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.08224679 |
| 61 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.07927472 |
| 62 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.05870608 |
| 63 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.05779270 |
| 64 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.05779270 |
| 65 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.05144088 |
| 66 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.03647881 |
| 67 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.02418655 |
| 68 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.01972267 |
| 69 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.01972267 |
| 70 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.01161699 |
| 71 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.99264967 |
| 72 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.97775958 |
| 73 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.97410249 |
| 74 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.96306251 |
| 75 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.93501653 |
| 76 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.93093797 |
| 77 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.93010724 |
| 78 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.91438905 |
| 79 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.89772466 |
| 80 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.89231225 |
| 81 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.89231225 |
| 82 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.88165427 |
| 83 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.87254557 |
| 84 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.86915778 |
| 85 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.86911782 |
| 86 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.86696085 |
| 87 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.85120388 |
| 88 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.83670534 |
| 89 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.83479083 |
| 90 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.83389838 |
| 91 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.83369240 |
| 92 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.83256606 |
| 93 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.82882363 |
| 94 | AR_20517297_ChIP-Seq_VCAP_Human | 0.81906271 |
| 95 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.81862683 |
| 96 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.80909689 |
| 97 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.80364492 |
| 98 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.79108601 |
| 99 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.78802932 |
| 100 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.78100131 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 4.30542519 |
| 2 | MP0008877_abnormal_DNA_methylation | 4.00803842 |
| 3 | MP0010094_abnormal_chromosome_stability | 3.15642753 |
| 4 | MP0004147_increased_porphyrin_level | 3.07360560 |
| 5 | MP0003787_abnormal_imprinting | 2.72110220 |
| 6 | MP0005084_abnormal_gallbladder_morpholo | 2.64735667 |
| 7 | MP0003693_abnormal_embryo_hatching | 2.42196353 |
| 8 | MP0009379_abnormal_foot_pigmentation | 2.36875988 |
| 9 | MP0006072_abnormal_retinal_apoptosis | 2.19511263 |
| 10 | MP0002102_abnormal_ear_morphology | 2.13838439 |
| 11 | MP0008058_abnormal_DNA_repair | 2.13090439 |
| 12 | MP0002736_abnormal_nociception_after | 1.97193701 |
| 13 | MP0000372_irregular_coat_pigmentation | 1.93260440 |
| 14 | MP0008875_abnormal_xenobiotic_pharmacok | 1.92920590 |
| 15 | MP0003121_genomic_imprinting | 1.89278982 |
| 16 | MP0001905_abnormal_dopamine_level | 1.86883078 |
| 17 | MP0005671_abnormal_response_to | 1.86811387 |
| 18 | MP0003122_maternal_imprinting | 1.82064615 |
| 19 | MP0002234_abnormal_pharynx_morphology | 1.77771217 |
| 20 | MP0008872_abnormal_physiological_respon | 1.72464600 |
| 21 | MP0005551_abnormal_eye_electrophysiolog | 1.70679533 |
| 22 | MP0002166_altered_tumor_susceptibility | 1.69532579 |
| 23 | MP0008789_abnormal_olfactory_epithelium | 1.69493256 |
| 24 | MP0002006_tumorigenesis | 1.67262235 |
| 25 | MP0001293_anophthalmia | 1.63898402 |
| 26 | MP0001968_abnormal_touch/_nociception | 1.58682108 |
| 27 | MP0005646_abnormal_pituitary_gland | 1.57050561 |
| 28 | MP0005075_abnormal_melanosome_morpholog | 1.56486364 |
| 29 | MP0004142_abnormal_muscle_tone | 1.50544819 |
| 30 | MP0004957_abnormal_blastocyst_morpholog | 1.44198939 |
| 31 | MP0006036_abnormal_mitochondrial_physio | 1.42292842 |
| 32 | MP0005389_reproductive_system_phenotype | 1.39283695 |
| 33 | MP0002876_abnormal_thyroid_physiology | 1.36681451 |
| 34 | MP0002160_abnormal_reproductive_system | 1.36142249 |
| 35 | MP0001986_abnormal_taste_sensitivity | 1.33976645 |
| 36 | MP0005253_abnormal_eye_physiology | 1.33613039 |
| 37 | MP0005499_abnormal_olfactory_system | 1.32756918 |
| 38 | MP0005394_taste/olfaction_phenotype | 1.32756918 |
| 39 | MP0003890_abnormal_embryonic-extraembry | 1.31770862 |
| 40 | MP0003111_abnormal_nucleus_morphology | 1.31600180 |
| 41 | MP0004885_abnormal_endolymph | 1.29583775 |
| 42 | MP0002837_dystrophic_cardiac_calcinosis | 1.27825587 |
| 43 | MP0002095_abnormal_skin_pigmentation | 1.27440868 |
| 44 | MP0006276_abnormal_autonomic_nervous | 1.23141875 |
| 45 | MP0001919_abnormal_reproductive_system | 1.23078885 |
| 46 | MP0008007_abnormal_cellular_replicative | 1.20662722 |
| 47 | MP0003186_abnormal_redox_activity | 1.19503791 |
| 48 | MP0002272_abnormal_nervous_system | 1.15042902 |
| 49 | MP0002138_abnormal_hepatobiliary_system | 1.14246057 |
| 50 | MP0003011_delayed_dark_adaptation | 1.12630474 |
| 51 | MP0003718_maternal_effect | 1.12348775 |
| 52 | MP0009745_abnormal_behavioral_response | 1.08487221 |
| 53 | MP0002735_abnormal_chemical_nociception | 1.06073586 |
| 54 | MP0001486_abnormal_startle_reflex | 1.05273063 |
| 55 | MP0004742_abnormal_vestibular_system | 1.02032511 |
| 56 | MP0002653_abnormal_ependyma_morphology | 1.01450761 |
| 57 | MP0008932_abnormal_embryonic_tissue | 1.01337099 |
| 58 | MP0001485_abnormal_pinna_reflex | 1.00617841 |
| 59 | MP0005410_abnormal_fertilization | 1.00420549 |
| 60 | MP0002163_abnormal_gland_morphology | 1.00345605 |
| 61 | MP0003786_premature_aging | 1.00222040 |
| 62 | MP0004043_abnormal_pH_regulation | 0.99428369 |
| 63 | MP0001835_abnormal_antigen_presentation | 0.98252353 |
| 64 | MP0001529_abnormal_vocalization | 0.97824709 |
| 65 | MP0004133_heterotaxia | 0.97264664 |
| 66 | MP0003252_abnormal_bile_duct | 0.96706397 |
| 67 | MP0002210_abnormal_sex_determination | 0.96000571 |
| 68 | MP0000427_abnormal_hair_cycle | 0.94247525 |
| 69 | MP0006035_abnormal_mitochondrial_morpho | 0.94116644 |
| 70 | MP0002009_preneoplasia | 0.93980255 |
| 71 | MP0003646_muscle_fatigue | 0.93949869 |
| 72 | MP0005195_abnormal_posterior_eye | 0.93336804 |
| 73 | MP0001929_abnormal_gametogenesis | 0.91415125 |
| 74 | MP0002938_white_spotting | 0.91108263 |
| 75 | MP0002148_abnormal_hypersensitivity_rea | 0.90638959 |
| 76 | MP0001727_abnormal_embryo_implantation | 0.90103416 |
| 77 | MP0002638_abnormal_pupillary_reflex | 0.88778362 |
| 78 | MP0004145_abnormal_muscle_electrophysio | 0.85667295 |
| 79 | MP0002752_abnormal_somatic_nervous | 0.84114961 |
| 80 | MP0002557_abnormal_social/conspecific_i | 0.81938507 |
| 81 | MP0009697_abnormal_copulation | 0.81218537 |
| 82 | MP0003195_calcinosis | 0.79691166 |
| 83 | MP0004215_abnormal_myocardial_fiber | 0.78811118 |
| 84 | MP0001963_abnormal_hearing_physiology | 0.77524455 |
| 85 | MP0001440_abnormal_grooming_behavior | 0.77415509 |
| 86 | MP0001800_abnormal_humoral_immune | 0.77363932 |
| 87 | MP0003077_abnormal_cell_cycle | 0.75177962 |
| 88 | MP0002184_abnormal_innervation | 0.72925506 |
| 89 | MP0000653_abnormal_sex_gland | 0.71187923 |
| 90 | MP0003806_abnormal_nucleotide_metabolis | 0.70082264 |
| 91 | MP0002733_abnormal_thermal_nociception | 0.69423144 |
| 92 | MP0001145_abnormal_male_reproductive | 0.69196516 |
| 93 | MP0003315_abnormal_perineum_morphology | 0.69042142 |
| 94 | MP0001970_abnormal_pain_threshold | 0.68773503 |
| 95 | MP0005083_abnormal_biliary_tract | 0.67926332 |
| 96 | MP0003879_abnormal_hair_cell | 0.67580901 |
| 97 | MP0000049_abnormal_middle_ear | 0.65600158 |
| 98 | MP0001119_abnormal_female_reproductive | 0.64936483 |
| 99 | MP0000613_abnormal_salivary_gland | 0.64417145 |
| 100 | MP0003698_abnormal_male_reproductive | 0.64163655 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.38275669 |
| 2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.07435887 |
| 3 | Acute encephalopathy (HP:0006846) | 3.84165728 |
| 4 | Mitochondrial inheritance (HP:0001427) | 3.81247378 |
| 5 | Progressive macrocephaly (HP:0004481) | 3.60705572 |
| 6 | Increased CSF lactate (HP:0002490) | 3.57049166 |
| 7 | B lymphocytopenia (HP:0010976) | 3.54078950 |
| 8 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.47261347 |
| 9 | Severe combined immunodeficiency (HP:0004430) | 3.42204516 |
| 10 | Hepatocellular necrosis (HP:0001404) | 3.34186930 |
| 11 | Abnormality of B cell number (HP:0010975) | 3.31679434 |
| 12 | Hypoproteinemia (HP:0003075) | 3.31344260 |
| 13 | Panhypogammaglobulinemia (HP:0003139) | 3.09532064 |
| 14 | Hepatic necrosis (HP:0002605) | 3.07365163 |
| 15 | Increased hepatocellular lipid droplets (HP:0006565) | 3.03990938 |
| 16 | Colon cancer (HP:0003003) | 3.03548428 |
| 17 | Pancreatic fibrosis (HP:0100732) | 3.02666036 |
| 18 | Thyroiditis (HP:0100646) | 3.01454521 |
| 19 | Reticulocytopenia (HP:0001896) | 2.99560804 |
| 20 | Cerebral edema (HP:0002181) | 2.89137076 |
| 21 | Molar tooth sign on MRI (HP:0002419) | 2.86819420 |
| 22 | Abnormality of midbrain morphology (HP:0002418) | 2.86819420 |
| 23 | Methylmalonic acidemia (HP:0002912) | 2.83852414 |
| 24 | Pancreatic cysts (HP:0001737) | 2.83408115 |
| 25 | Combined immunodeficiency (HP:0005387) | 2.79274358 |
| 26 | Lipid accumulation in hepatocytes (HP:0006561) | 2.73482029 |
| 27 | Absent/shortened dynein arms (HP:0200106) | 2.71405375 |
| 28 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.71405375 |
| 29 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.70523830 |
| 30 | Decreased central vision (HP:0007663) | 2.70130588 |
| 31 | Pendular nystagmus (HP:0012043) | 2.69629334 |
| 32 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.67005584 |
| 33 | Absent thumb (HP:0009777) | 2.64425788 |
| 34 | Increased serum lactate (HP:0002151) | 2.61077324 |
| 35 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.59977521 |
| 36 | Increased intramyocellular lipid droplets (HP:0012240) | 2.55036755 |
| 37 | IgG deficiency (HP:0004315) | 2.49770218 |
| 38 | Hyperglycinemia (HP:0002154) | 2.49250127 |
| 39 | Hypoplasia of the thymus (HP:0000778) | 2.46469698 |
| 40 | Lactic acidosis (HP:0003128) | 2.45269407 |
| 41 | Abnormality of the pons (HP:0007361) | 2.43161754 |
| 42 | Optic disc pallor (HP:0000543) | 2.42711433 |
| 43 | True hermaphroditism (HP:0010459) | 2.39966157 |
| 44 | Hypoplasia of the pons (HP:0012110) | 2.39680002 |
| 45 | Abnormality of DNA repair (HP:0003254) | 2.35530177 |
| 46 | Abnormal number of erythroid precursors (HP:0012131) | 2.33670825 |
| 47 | Abnormality of the ileum (HP:0001549) | 2.32646349 |
| 48 | Chromsome breakage (HP:0040012) | 2.32557653 |
| 49 | Renal Fanconi syndrome (HP:0001994) | 2.31723112 |
| 50 | Nephronophthisis (HP:0000090) | 2.31120137 |
| 51 | Abolished electroretinogram (ERG) (HP:0000550) | 2.29330167 |
| 52 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.29303078 |
| 53 | Meckel diverticulum (HP:0002245) | 2.28992527 |
| 54 | Congenital stationary night blindness (HP:0007642) | 2.27084112 |
| 55 | Birth length less than 3rd percentile (HP:0003561) | 2.25259477 |
| 56 | Methylmalonic aciduria (HP:0012120) | 2.23622255 |
| 57 | Leukodystrophy (HP:0002415) | 2.22521855 |
| 58 | Abnormality of the labia minora (HP:0012880) | 2.17221232 |
| 59 | Microvesicular hepatic steatosis (HP:0001414) | 2.16095606 |
| 60 | 3-Methylglutaconic aciduria (HP:0003535) | 2.14864102 |
| 61 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.14353412 |
| 62 | Abnormal ciliary motility (HP:0012262) | 2.12971297 |
| 63 | Congenital, generalized hypertrichosis (HP:0004540) | 2.12445770 |
| 64 | Attenuation of retinal blood vessels (HP:0007843) | 2.11707506 |
| 65 | Asplenia (HP:0001746) | 2.07731157 |
| 66 | Pancytopenia (HP:0001876) | 2.05364120 |
| 67 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.04362881 |
| 68 | Respiratory failure (HP:0002878) | 2.03853168 |
| 69 | Volvulus (HP:0002580) | 2.03205642 |
| 70 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.03129722 |
| 71 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.03129722 |
| 72 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.01040137 |
| 73 | Macrocytic anemia (HP:0001972) | 1.98489761 |
| 74 | Increased muscle lipid content (HP:0009058) | 1.97394678 |
| 75 | Supernumerary spleens (HP:0009799) | 1.96523822 |
| 76 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.94932078 |
| 77 | Dicarboxylic aciduria (HP:0003215) | 1.94932078 |
| 78 | Exercise intolerance (HP:0003546) | 1.94657993 |
| 79 | Abnormality of alanine metabolism (HP:0010916) | 1.93823554 |
| 80 | Hyperalaninemia (HP:0003348) | 1.93823554 |
| 81 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.93823554 |
| 82 | Abnormality of the renal collecting system (HP:0004742) | 1.93546993 |
| 83 | Agammaglobulinemia (HP:0004432) | 1.93500435 |
| 84 | Lethargy (HP:0001254) | 1.92861440 |
| 85 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.89680260 |
| 86 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.89680260 |
| 87 | Type II lissencephaly (HP:0007260) | 1.87753505 |
| 88 | Intestinal atresia (HP:0011100) | 1.87655892 |
| 89 | Renal cortical cysts (HP:0000803) | 1.84491575 |
| 90 | T lymphocytopenia (HP:0005403) | 1.84126017 |
| 91 | Sclerocornea (HP:0000647) | 1.83247684 |
| 92 | Erythroderma (HP:0001019) | 1.81349089 |
| 93 | Medial flaring of the eyebrow (HP:0010747) | 1.80046362 |
| 94 | Abnormality of the renal medulla (HP:0100957) | 1.79754589 |
| 95 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.79745264 |
| 96 | Duplicated collecting system (HP:0000081) | 1.79209527 |
| 97 | Respiratory difficulties (HP:0002880) | 1.78236489 |
| 98 | Abnormality of eosinophils (HP:0001879) | 1.77331666 |
| 99 | Thyroid-stimulating hormone excess (HP:0002925) | 1.76482168 |
| 100 | Abnormality of the prostate (HP:0008775) | 1.75916517 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 3.48005101 |
| 2 | STK16 | 3.31756643 |
| 3 | ZAK | 3.15110495 |
| 4 | CDC7 | 2.85470972 |
| 5 | NUAK1 | 2.71869430 |
| 6 | MAP4K2 | 2.68992009 |
| 7 | EIF2AK3 | 2.40800785 |
| 8 | BUB1 | 2.04360294 |
| 9 | TLK1 | 1.98272766 |
| 10 | NME1 | 1.97015163 |
| 11 | KDR | 1.94094663 |
| 12 | NEK1 | 1.91886962 |
| 13 | BMPR1B | 1.91882954 |
| 14 | PLK4 | 1.91467847 |
| 15 | FRK | 1.86369437 |
| 16 | VRK1 | 1.82400222 |
| 17 | WNK4 | 1.76603159 |
| 18 | PLK3 | 1.74056168 |
| 19 | OXSR1 | 1.66515138 |
| 20 | TAOK3 | 1.64124994 |
| 21 | CDK19 | 1.59872701 |
| 22 | DYRK2 | 1.58903302 |
| 23 | TAF1 | 1.56192761 |
| 24 | PLK2 | 1.51433545 |
| 25 | BCKDK | 1.45102627 |
| 26 | ADRBK2 | 1.43690423 |
| 27 | WNK3 | 1.43123876 |
| 28 | MAPK13 | 1.42539096 |
| 29 | GRK1 | 1.40419686 |
| 30 | TIE1 | 1.38897601 |
| 31 | STK39 | 1.34996829 |
| 32 | CSNK1G3 | 1.23405189 |
| 33 | CSNK1G2 | 1.21216865 |
| 34 | TESK2 | 1.20716933 |
| 35 | CDK8 | 1.19425905 |
| 36 | MAPKAPK5 | 1.18670745 |
| 37 | DAPK1 | 1.16540845 |
| 38 | ATR | 1.15711192 |
| 39 | TSSK6 | 1.14368163 |
| 40 | PLK1 | 1.08837505 |
| 41 | MAPKAPK3 | 1.08069868 |
| 42 | BCR | 1.05074907 |
| 43 | MKNK2 | 1.02238526 |
| 44 | EIF2AK2 | 0.97742708 |
| 45 | CSNK1G1 | 0.94399550 |
| 46 | PINK1 | 0.92968650 |
| 47 | KIT | 0.87143510 |
| 48 | CAMKK2 | 0.84322742 |
| 49 | WEE1 | 0.82485311 |
| 50 | CSNK1A1L | 0.81818814 |
| 51 | MST4 | 0.81423690 |
| 52 | LIMK1 | 0.81402662 |
| 53 | MKNK1 | 0.80271543 |
| 54 | CHEK2 | 0.79662879 |
| 55 | SRPK1 | 0.79163008 |
| 56 | NEK2 | 0.78015850 |
| 57 | GRK5 | 0.75367236 |
| 58 | INSRR | 0.73727192 |
| 59 | FES | 0.72842713 |
| 60 | PBK | 0.72447276 |
| 61 | TEC | 0.71217833 |
| 62 | TNIK | 0.70663810 |
| 63 | MINK1 | 0.69197146 |
| 64 | TTK | 0.68363669 |
| 65 | CDK14 | 0.68264005 |
| 66 | AURKB | 0.67122824 |
| 67 | PRKCG | 0.64955861 |
| 68 | RPS6KA5 | 0.64196994 |
| 69 | DAPK2 | 0.62183733 |
| 70 | CSNK2A2 | 0.59549854 |
| 71 | PRKCI | 0.58526490 |
| 72 | TXK | 0.58077916 |
| 73 | PRKCQ | 0.55070100 |
| 74 | CSNK2A1 | 0.54864778 |
| 75 | AURKA | 0.54333336 |
| 76 | ATM | 0.52051266 |
| 77 | EPHB2 | 0.50709806 |
| 78 | MAP2K7 | 0.49414541 |
| 79 | CCNB1 | 0.48027799 |
| 80 | CSNK1E | 0.47699721 |
| 81 | CDK15 | 0.45870836 |
| 82 | TRIM28 | 0.45177897 |
| 83 | CDK18 | 0.44922993 |
| 84 | CDK11A | 0.43898864 |
| 85 | WNK1 | 0.41227135 |
| 86 | SYK | 0.41180612 |
| 87 | EIF2AK1 | 0.40530460 |
| 88 | PIK3CG | 0.39801854 |
| 89 | CSNK1A1 | 0.39144087 |
| 90 | PHKG1 | 0.37857741 |
| 91 | PHKG2 | 0.37857741 |
| 92 | PRKACA | 0.36307858 |
| 93 | PIM2 | 0.35695176 |
| 94 | DAPK3 | 0.35580492 |
| 95 | ABL2 | 0.35410649 |
| 96 | CDK3 | 0.35341352 |
| 97 | ILK | 0.35306300 |
| 98 | PIM1 | 0.35177263 |
| 99 | PDK2 | 0.34965946 |
| 100 | MAP3K4 | 0.33476267 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.28129230 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.56526506 |
| 3 | DNA replication_Homo sapiens_hsa03030 | 3.43269046 |
| 4 | Ribosome_Homo sapiens_hsa03010 | 3.30432983 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 3.17801213 |
| 6 | Mismatch repair_Homo sapiens_hsa03430 | 3.07356010 |
| 7 | Protein export_Homo sapiens_hsa03060 | 2.67344328 |
| 8 | Homologous recombination_Homo sapiens_hsa03440 | 2.56126951 |
| 9 | RNA polymerase_Homo sapiens_hsa03020 | 2.51305767 |
| 10 | Huntingtons disease_Homo sapiens_hsa05016 | 2.16745098 |
| 11 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.07836191 |
| 12 | Base excision repair_Homo sapiens_hsa03410 | 2.07399513 |
| 13 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.06533206 |
| 14 | Alzheimers disease_Homo sapiens_hsa05010 | 2.04396771 |
| 15 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.04116439 |
| 16 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.96340581 |
| 17 | RNA degradation_Homo sapiens_hsa03018 | 1.87495366 |
| 18 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.82865221 |
| 19 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.82309246 |
| 20 | Asthma_Homo sapiens_hsa05310 | 1.78799881 |
| 21 | Spliceosome_Homo sapiens_hsa03040 | 1.76403929 |
| 22 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.71846649 |
| 23 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.71553801 |
| 24 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.70915317 |
| 25 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.65611931 |
| 26 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.57546829 |
| 27 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.56821791 |
| 28 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.44996035 |
| 29 | Phototransduction_Homo sapiens_hsa04744 | 1.43399543 |
| 30 | Basal transcription factors_Homo sapiens_hsa03022 | 1.35234683 |
| 31 | RNA transport_Homo sapiens_hsa03013 | 1.35136277 |
| 32 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.31643868 |
| 33 | Purine metabolism_Homo sapiens_hsa00230 | 1.30734446 |
| 34 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.24339878 |
| 35 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.20969512 |
| 36 | Allograft rejection_Homo sapiens_hsa05330 | 1.18203609 |
| 37 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.16655839 |
| 38 | Peroxisome_Homo sapiens_hsa04146 | 1.08715300 |
| 39 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.03566029 |
| 40 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.99114727 |
| 41 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.98683528 |
| 42 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.94714256 |
| 43 | Sulfur relay system_Homo sapiens_hsa04122 | 0.93471275 |
| 44 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.90277333 |
| 45 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.90032245 |
| 46 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.87018935 |
| 47 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.85558781 |
| 48 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.85540260 |
| 49 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.84750711 |
| 50 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.81800310 |
| 51 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.79908956 |
| 52 | Cell cycle_Homo sapiens_hsa04110 | 0.78146903 |
| 53 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.75210468 |
| 54 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.74483701 |
| 55 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.72713447 |
| 56 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.71286051 |
| 57 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.70919569 |
| 58 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.69592027 |
| 59 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.67604115 |
| 60 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.63415327 |
| 61 | Metabolic pathways_Homo sapiens_hsa01100 | 0.62823376 |
| 62 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.61742320 |
| 63 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.61514753 |
| 64 | Olfactory transduction_Homo sapiens_hsa04740 | 0.57530075 |
| 65 | Nicotine addiction_Homo sapiens_hsa05033 | 0.56992684 |
| 66 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.56598699 |
| 67 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.56391671 |
| 68 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.56139275 |
| 69 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.55117280 |
| 70 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.53991774 |
| 71 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.48539160 |
| 72 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.48042679 |
| 73 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.46327428 |
| 74 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.46011160 |
| 75 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.44880304 |
| 76 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.43002657 |
| 77 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.42965074 |
| 78 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.41595769 |
| 79 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.41545456 |
| 80 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.39530788 |
| 81 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.37365721 |
| 82 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.36570333 |
| 83 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.35796531 |
| 84 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.34713188 |
| 85 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.32113467 |
| 86 | Taste transduction_Homo sapiens_hsa04742 | 0.31095144 |
| 87 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.29592847 |
| 88 | Retinol metabolism_Homo sapiens_hsa00830 | 0.28371570 |
| 89 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.28100792 |
| 90 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.27382260 |
| 91 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.26436711 |
| 92 | Morphine addiction_Homo sapiens_hsa05032 | 0.25447559 |
| 93 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.22118343 |
| 94 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.21202433 |
| 95 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.20987847 |
| 96 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.20822783 |
| 97 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.18829059 |
| 98 | Carbon metabolism_Homo sapiens_hsa01200 | 0.17983895 |
| 99 | Salivary secretion_Homo sapiens_hsa04970 | 0.17376004 |
| 100 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.17283589 |

