

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 5.20279831 |
| 2 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.90762220 |
| 3 | cytidine catabolic process (GO:0006216) | 4.42044489 |
| 4 | cytidine deamination (GO:0009972) | 4.42044489 |
| 5 | cytidine metabolic process (GO:0046087) | 4.42044489 |
| 6 | negative regulation of cell killing (GO:0031342) | 4.24722889 |
| 7 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.24722889 |
| 8 | kidney morphogenesis (GO:0060993) | 4.19207447 |
| 9 | respiratory tube development (GO:0030323) | 4.09974006 |
| 10 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 4.02010229 |
| 11 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.00478945 |
| 12 | negative T cell selection (GO:0043383) | 3.95232936 |
| 13 | regulation of memory T cell differentiation (GO:0043380) | 3.86600659 |
| 14 | cellular response to interleukin-15 (GO:0071350) | 3.84407271 |
| 15 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.83139445 |
| 16 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.77483308 |
| 17 | response to interferon-beta (GO:0035456) | 3.77279909 |
| 18 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.74086015 |
| 19 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.73668537 |
| 20 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.62532994 |
| 21 | positive regulation of defense response to virus by host (GO:0002230) | 3.51099746 |
| 22 | mast cell activation (GO:0045576) | 3.44467733 |
| 23 | base-excision repair, AP site formation (GO:0006285) | 3.40091446 |
| 24 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.39422750 |
| 25 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.39422750 |
| 26 | cellular extravasation (GO:0045123) | 3.38535927 |
| 27 | cellular response to interferon-beta (GO:0035458) | 3.38308562 |
| 28 | regulation of hypersensitivity (GO:0002883) | 3.36387016 |
| 29 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.33742413 |
| 30 | regulation of regulatory T cell differentiation (GO:0045589) | 3.32710977 |
| 31 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.28987370 |
| 32 | negative regulation of T cell mediated immunity (GO:0002710) | 3.28672045 |
| 33 | negative thymic T cell selection (GO:0045060) | 3.25016414 |
| 34 | microglial cell activation (GO:0001774) | 3.23631666 |
| 35 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.19121551 |
| 36 | response to interleukin-15 (GO:0070672) | 3.17737452 |
| 37 | cartilage morphogenesis (GO:0060536) | 3.17552493 |
| 38 | lung epithelium development (GO:0060428) | 3.16627276 |
| 39 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.16384062 |
| 40 | myeloid leukocyte mediated immunity (GO:0002444) | 3.15118239 |
| 41 | neutrophil mediated immunity (GO:0002446) | 3.13927061 |
| 42 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.13269426 |
| 43 | regulation of T-helper 1 type immune response (GO:0002825) | 3.12709899 |
| 44 | positive regulation of B cell mediated immunity (GO:0002714) | 3.11757106 |
| 45 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 3.11757106 |
| 46 | positive T cell selection (GO:0043368) | 3.11577583 |
| 47 | metanephric tubule development (GO:0072170) | 3.10159892 |
| 48 | metanephric nephron tubule development (GO:0072234) | 3.10159892 |
| 49 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.10041329 |
| 50 | mast cell activation involved in immune response (GO:0002279) | 3.09820621 |
| 51 | mast cell degranulation (GO:0043303) | 3.09820621 |
| 52 | immunoglobulin mediated immune response (GO:0016064) | 3.09814186 |
| 53 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.07879268 |
| 54 | regulation of T-helper 1 cell differentiation (GO:0045625) | 3.02311746 |
| 55 | negative regulation of growth of symbiont in host (GO:0044130) | 3.02095364 |
| 56 | negative regulation of growth of symbiont involved in interaction with host (GO:0044146) | 3.02095364 |
| 57 | modulation of growth of symbiont involved in interaction with host (GO:0044144) | 3.02095364 |
| 58 | regulation of growth of symbiont in host (GO:0044126) | 3.02095364 |
| 59 | negative regulation of interleukin-12 production (GO:0032695) | 3.00391519 |
| 60 | regulation of T cell receptor signaling pathway (GO:0050856) | 2.99066820 |
| 61 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.96094333 |
| 62 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 2.95559224 |
| 63 | B cell mediated immunity (GO:0019724) | 2.91207944 |
| 64 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 2.87523625 |
| 65 | regulation of germinal center formation (GO:0002634) | 2.86187129 |
| 66 | positive thymic T cell selection (GO:0045059) | 2.83434251 |
| 67 | positive regulation of DNA recombination (GO:0045911) | 2.81059774 |
| 68 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.80162256 |
| 69 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.77818718 |
| 70 | positive regulation of T cell differentiation in thymus (GO:0033089) | 2.74530663 |
| 71 | negative regulation of viral genome replication (GO:0045071) | 2.74460460 |
| 72 | positive regulation of isotype switching (GO:0045830) | 2.69755751 |
| 73 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.69724702 |
| 74 | metanephric nephron epithelium development (GO:0072243) | 2.69568361 |
| 75 | regulation of B cell differentiation (GO:0045577) | 2.69355493 |
| 76 | positive regulation of T-helper 1 type immune response (GO:0002827) | 2.68547437 |
| 77 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.66333555 |
| 78 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 2.64539981 |
| 79 | negative regulation of adaptive immune response (GO:0002820) | 2.64176854 |
| 80 | interferon-gamma production (GO:0032609) | 2.60379358 |
| 81 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.59258297 |
| 82 | DNA demethylation (GO:0080111) | 2.57230228 |
| 83 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.57177305 |
| 84 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 2.56901134 |
| 85 | regulation of immunoglobulin secretion (GO:0051023) | 2.55420553 |
| 86 | deoxyribonucleotide catabolic process (GO:0009264) | 2.55388560 |
| 87 | negative regulation of alpha-beta T cell activation (GO:0046636) | 2.55130768 |
| 88 | T cell migration (GO:0072678) | 2.54983221 |
| 89 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.52819703 |
| 90 | regulation of chemokine biosynthetic process (GO:0045073) | 2.51599638 |
| 91 | regulation of acute inflammatory response to antigenic stimulus (GO:0002864) | 2.50087239 |
| 92 | negative regulation of mast cell activation (GO:0033004) | 2.49908264 |
| 93 | deoxyribose phosphate catabolic process (GO:0046386) | 2.49822044 |
| 94 | positive regulation of interleukin-17 production (GO:0032740) | 2.49146671 |
| 95 | neutrophil activation involved in immune response (GO:0002283) | 2.48484842 |
| 96 | positive regulation of cell fate commitment (GO:0010455) | 2.48231459 |
| 97 | regulation of B cell mediated immunity (GO:0002712) | 2.47282774 |
| 98 | metanephric epithelium development (GO:0072207) | 2.47228928 |
| 99 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.45041023 |
| 100 | DNA dealkylation (GO:0035510) | 2.44388530 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 6.13692235 |
| 2 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 4.21858429 |
| 3 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 4.02649842 |
| 4 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.87670216 |
| 5 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.56404647 |
| 6 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.30697193 |
| 7 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.27818820 |
| 8 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.14658112 |
| 9 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 3.01032902 |
| 10 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.80449785 |
| 11 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.41876498 |
| 12 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.28671942 |
| 13 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.24509726 |
| 14 | MYB_26560356_Chip-Seq_TH2_Human | 2.18471384 |
| 15 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.15149070 |
| 16 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.01160992 |
| 17 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.97917595 |
| 18 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.95692247 |
| 19 | GATA3_26560356_Chip-Seq_TH2_Human | 1.93879868 |
| 20 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.90665105 |
| 21 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.89624082 |
| 22 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.89023356 |
| 23 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.88994282 |
| 24 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.87785170 |
| 25 | VDR_22108803_ChIP-Seq_LS180_Human | 1.84641040 |
| 26 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.84320059 |
| 27 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.84112992 |
| 28 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.75449341 |
| 29 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.74276069 |
| 30 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.72147823 |
| 31 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.71499892 |
| 32 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.71014954 |
| 33 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.70932667 |
| 34 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.64911616 |
| 35 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.62542019 |
| 36 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.62229047 |
| 37 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.61196244 |
| 38 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.57753872 |
| 39 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.55652238 |
| 40 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.44887453 |
| 41 | MYB_26560356_Chip-Seq_TH1_Human | 1.44228625 |
| 42 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.44153398 |
| 43 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.43716937 |
| 44 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.41550418 |
| 45 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.37445824 |
| 46 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.37211118 |
| 47 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.25945741 |
| 48 | EWS_26573619_Chip-Seq_HEK293_Human | 1.25027695 |
| 49 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.22053090 |
| 50 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.20900868 |
| 51 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.18221771 |
| 52 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.17932894 |
| 53 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.17597749 |
| 54 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.17597749 |
| 55 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.15993132 |
| 56 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.10615761 |
| 57 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.09844950 |
| 58 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.08190546 |
| 59 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.07473291 |
| 60 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.06328747 |
| 61 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.06328747 |
| 62 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.06261512 |
| 63 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.06260016 |
| 64 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.05527195 |
| 65 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.04664242 |
| 66 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.03703254 |
| 67 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.02673821 |
| 68 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.00004949 |
| 69 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 0.99133130 |
| 70 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.98873959 |
| 71 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.98609954 |
| 72 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.98229051 |
| 73 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.98089399 |
| 74 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.97835262 |
| 75 | AR_20517297_ChIP-Seq_VCAP_Human | 0.96984062 |
| 76 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.96331584 |
| 77 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.95855819 |
| 78 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.94714841 |
| 79 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.94272867 |
| 80 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 0.93390448 |
| 81 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.93110865 |
| 82 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.93040117 |
| 83 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.92743713 |
| 84 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.92653488 |
| 85 | GATA3_26560356_Chip-Seq_TH1_Human | 0.92615906 |
| 86 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.91344681 |
| 87 | UTX_26944678_Chip-Seq_JUKART_Human | 0.90930805 |
| 88 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.90758944 |
| 89 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.90721640 |
| 90 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.90338428 |
| 91 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.89907112 |
| 92 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.89245965 |
| 93 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.88878115 |
| 94 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.87182664 |
| 95 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.87148717 |
| 96 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.85910996 |
| 97 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 0.85078533 |
| 98 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.84896826 |
| 99 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.84896826 |
| 100 | MAF_26560356_Chip-Seq_TH2_Human | 0.84576961 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.47241161 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.87576152 |
| 3 | MP0009785_altered_susceptibility_to | 2.99463634 |
| 4 | MP0002148_abnormal_hypersensitivity_rea | 2.99417076 |
| 5 | MP0003724_increased_susceptibility_to | 2.87732422 |
| 6 | MP0001800_abnormal_humoral_immune | 2.80340939 |
| 7 | MP0005000_abnormal_immune_tolerance | 2.69848243 |
| 8 | MP0000685_abnormal_immune_system | 2.57319728 |
| 9 | MP0003763_abnormal_thymus_physiology | 2.56951176 |
| 10 | MP0008057_abnormal_DNA_replication | 2.48732932 |
| 11 | MP0002723_abnormal_immune_serum | 2.46773732 |
| 12 | MP0009278_abnormal_bone_marrow | 2.43713893 |
| 13 | MP0000569_abnormal_digit_pigmentation | 2.35770780 |
| 14 | MP0003436_decreased_susceptibility_to | 2.31576720 |
| 15 | MP0005025_abnormal_response_to | 2.30898820 |
| 16 | MP0002452_abnormal_antigen_presenting | 2.25901815 |
| 17 | MP0002420_abnormal_adaptive_immunity | 2.23867391 |
| 18 | MP0001819_abnormal_immune_cell | 2.22806033 |
| 19 | MP0005646_abnormal_pituitary_gland | 2.17734727 |
| 20 | MP0002166_altered_tumor_susceptibility | 2.16592282 |
| 21 | MP0008877_abnormal_DNA_methylation | 2.12070802 |
| 22 | MP0002102_abnormal_ear_morphology | 2.11463969 |
| 23 | MP0002419_abnormal_innate_immunity | 2.06641814 |
| 24 | MP0001790_abnormal_immune_system | 2.05260776 |
| 25 | MP0005387_immune_system_phenotype | 2.05260776 |
| 26 | MP0002653_abnormal_ependyma_morphology | 1.96289080 |
| 27 | MP0005174_abnormal_tail_pigmentation | 1.94391546 |
| 28 | MP0002398_abnormal_bone_marrow | 1.87228931 |
| 29 | MP0009764_decreased_sensitivity_to | 1.86068535 |
| 30 | MP0002006_tumorigenesis | 1.84588004 |
| 31 | MP0003191_abnormal_cellular_cholesterol | 1.82916573 |
| 32 | MP0000015_abnormal_ear_pigmentation | 1.81063463 |
| 33 | MP0006054_spinal_hemorrhage | 1.75635934 |
| 34 | MP0000716_abnormal_immune_system | 1.74514406 |
| 35 | MP0005464_abnormal_platelet_physiology | 1.71341569 |
| 36 | MP0001346_abnormal_lacrimal_gland | 1.70020642 |
| 37 | MP0001845_abnormal_inflammatory_respons | 1.58420701 |
| 38 | MP0002405_respiratory_system_inflammati | 1.55637688 |
| 39 | MP0000689_abnormal_spleen_morphology | 1.51684091 |
| 40 | MP0006082_CNS_inflammation | 1.49356880 |
| 41 | MP0003806_abnormal_nucleotide_metabolis | 1.46379446 |
| 42 | MP0001545_abnormal_hematopoietic_system | 1.46137430 |
| 43 | MP0005397_hematopoietic_system_phenotyp | 1.46137430 |
| 44 | MP0004381_abnormal_hair_follicle | 1.44340614 |
| 45 | MP0002429_abnormal_blood_cell | 1.44202665 |
| 46 | MP0009840_abnormal_foam_cell | 1.38308438 |
| 47 | MP0003786_premature_aging | 1.36781355 |
| 48 | MP0005075_abnormal_melanosome_morpholog | 1.33800858 |
| 49 | MP0010094_abnormal_chromosome_stability | 1.33326214 |
| 50 | MP0001533_abnormal_skeleton_physiology | 1.33100115 |
| 51 | MP0002722_abnormal_immune_system | 1.31109184 |
| 52 | MP0002277_abnormal_respiratory_mucosa | 1.27581633 |
| 53 | MP0002095_abnormal_skin_pigmentation | 1.25937855 |
| 54 | MP0009333_abnormal_splenocyte_physiolog | 1.22908579 |
| 55 | MP0002876_abnormal_thyroid_physiology | 1.20160551 |
| 56 | MP0001853_heart_inflammation | 1.20120654 |
| 57 | MP0003195_calcinosis | 1.19000839 |
| 58 | MP0000703_abnormal_thymus_morphology | 1.16116411 |
| 59 | MP0008469_abnormal_protein_level | 1.15049266 |
| 60 | MP0004947_skin_inflammation | 1.13440508 |
| 61 | MP0003252_abnormal_bile_duct | 1.09168481 |
| 62 | MP0003787_abnormal_imprinting | 1.08096155 |
| 63 | MP0003950_abnormal_plasma_membrane | 1.08007474 |
| 64 | MP0003866_abnormal_defecation | 1.05003074 |
| 65 | MP0009763_increased_sensitivity_to | 1.04709703 |
| 66 | MP0008058_abnormal_DNA_repair | 0.96766401 |
| 67 | MP0005084_abnormal_gallbladder_morpholo | 0.95135691 |
| 68 | MP0005310_abnormal_salivary_gland | 0.94483556 |
| 69 | MP0008872_abnormal_physiological_respon | 0.92997653 |
| 70 | MP0000427_abnormal_hair_cycle | 0.89192654 |
| 71 | MP0010155_abnormal_intestine_physiology | 0.89122462 |
| 72 | MP0003303_peritoneal_inflammation | 0.87528994 |
| 73 | MP0001663_abnormal_digestive_system | 0.85869333 |
| 74 | MP0006036_abnormal_mitochondrial_physio | 0.85457293 |
| 75 | MP0002163_abnormal_gland_morphology | 0.84297661 |
| 76 | MP0008789_abnormal_olfactory_epithelium | 0.83489337 |
| 77 | MP0004885_abnormal_endolymph | 0.82566135 |
| 78 | MP0003656_abnormal_erythrocyte_physiolo | 0.82132796 |
| 79 | MP0006072_abnormal_retinal_apoptosis | 0.81281910 |
| 80 | MP0001986_abnormal_taste_sensitivity | 0.80567742 |
| 81 | MP0000372_irregular_coat_pigmentation | 0.79640056 |
| 82 | MP0005164_abnormal_response_to | 0.79332509 |
| 83 | MP0002019_abnormal_tumor_incidence | 0.78973063 |
| 84 | MP0009765_abnormal_xenobiotic_induced | 0.76705617 |
| 85 | MP0005551_abnormal_eye_electrophysiolog | 0.76657684 |
| 86 | MP0005058_abnormal_lysosome_morphology | 0.76269878 |
| 87 | MP0001501_abnormal_sleep_pattern | 0.75030986 |
| 88 | MP0008875_abnormal_xenobiotic_pharmacok | 0.74224970 |
| 89 | MP0005248_abnormal_Harderian_gland | 0.71542674 |
| 90 | MP0000465_gastrointestinal_hemorrhage | 0.71529496 |
| 91 | MP0000343_altered_response_to | 0.69340247 |
| 92 | MP0001119_abnormal_female_reproductive | 0.69139665 |
| 93 | MP0009379_abnormal_foot_pigmentation | 0.66700802 |
| 94 | MP0003186_abnormal_redox_activity | 0.65389030 |
| 95 | MP0008873_increased_physiological_sensi | 0.64954483 |
| 96 | MP0005410_abnormal_fertilization | 0.62428205 |
| 97 | MP0005167_abnormal_blood-brain_barrier | 0.61855873 |
| 98 | MP0005266_abnormal_metabolism | 0.61797005 |
| 99 | MP0002396_abnormal_hematopoietic_system | 0.61762559 |
| 100 | MP0002837_dystrophic_cardiac_calcinosis | 0.60976647 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Elevated erythrocyte sedimentation rate (HP:0003565) | 5.06486082 |
| 2 | T lymphocytopenia (HP:0005403) | 4.88652137 |
| 3 | Abnormality of T cell number (HP:0011839) | 4.53164882 |
| 4 | Stomatitis (HP:0010280) | 4.11314045 |
| 5 | IgG deficiency (HP:0004315) | 4.01258235 |
| 6 | Abnormality of eosinophils (HP:0001879) | 3.68866271 |
| 7 | Severe combined immunodeficiency (HP:0004430) | 3.62839245 |
| 8 | Eosinophilia (HP:0001880) | 3.52735772 |
| 9 | Abnormality of T cells (HP:0002843) | 3.45697277 |
| 10 | Retrobulbar optic neuritis (HP:0100654) | 3.29666476 |
| 11 | Optic neuritis (HP:0100653) | 3.29666476 |
| 12 | Thyroiditis (HP:0100646) | 3.21320961 |
| 13 | Decreased central vision (HP:0007663) | 3.11984142 |
| 14 | Abnormality of the prostate (HP:0008775) | 3.07375782 |
| 15 | B lymphocytopenia (HP:0010976) | 3.02640716 |
| 16 | Myositis (HP:0100614) | 2.99580716 |
| 17 | Abnormality of B cell number (HP:0010975) | 2.98982198 |
| 18 | Duplicated collecting system (HP:0000081) | 2.95658778 |
| 19 | Combined immunodeficiency (HP:0005387) | 2.94476618 |
| 20 | Orchitis (HP:0100796) | 2.94453972 |
| 21 | Panhypogammaglobulinemia (HP:0003139) | 2.93116214 |
| 22 | Autoimmune hemolytic anemia (HP:0001890) | 2.88033302 |
| 23 | 3-Methylglutaconic aciduria (HP:0003535) | 2.87136063 |
| 24 | Granulocytopenia (HP:0001913) | 2.86992953 |
| 25 | Leukocytosis (HP:0001974) | 2.84408872 |
| 26 | Recurrent bacterial skin infections (HP:0005406) | 2.81112158 |
| 27 | Abnormality of the renal collecting system (HP:0004742) | 2.80288565 |
| 28 | Recurrent fungal infections (HP:0002841) | 2.78816522 |
| 29 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.73070016 |
| 30 | Pulmonary infiltrates (HP:0002113) | 2.60346047 |
| 31 | True hermaphroditism (HP:0010459) | 2.57682879 |
| 32 | Dyschromatopsia (HP:0007641) | 2.54576743 |
| 33 | Recurrent abscess formation (HP:0002722) | 2.53741946 |
| 34 | Vasculitis (HP:0002633) | 2.49066138 |
| 35 | Encephalitis (HP:0002383) | 2.47470148 |
| 36 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.47420612 |
| 37 | Recurrent viral infections (HP:0004429) | 2.44965986 |
| 38 | Hypoplasia of the thymus (HP:0000778) | 2.44638318 |
| 39 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.44030240 |
| 40 | Recurrent cutaneous fungal infections (HP:0011370) | 2.43196903 |
| 41 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.43196903 |
| 42 | Mediastinal lymphadenopathy (HP:0100721) | 2.40906319 |
| 43 | Abolished electroretinogram (ERG) (HP:0000550) | 2.39933078 |
| 44 | Increased IgM level (HP:0003496) | 2.36221014 |
| 45 | Nephronophthisis (HP:0000090) | 2.32990677 |
| 46 | Abnormality of T cell physiology (HP:0011840) | 2.32792370 |
| 47 | Meningitis (HP:0001287) | 2.32565215 |
| 48 | Hemoptysis (HP:0002105) | 2.31326045 |
| 49 | Chronic obstructive pulmonary disease (HP:0006510) | 2.30869333 |
| 50 | Obstructive lung disease (HP:0006536) | 2.30869333 |
| 51 | Congenital stationary night blindness (HP:0007642) | 2.30740617 |
| 52 | Recurrent bronchitis (HP:0002837) | 2.27736363 |
| 53 | Thrombocytosis (HP:0001894) | 2.25587503 |
| 54 | Abnormality of male internal genitalia (HP:0000022) | 2.24291660 |
| 55 | Abnormality of the pons (HP:0007361) | 2.23348108 |
| 56 | Pancreatic cysts (HP:0001737) | 2.22061130 |
| 57 | Mitochondrial inheritance (HP:0001427) | 2.21841622 |
| 58 | Hepatocellular necrosis (HP:0001404) | 2.21734498 |
| 59 | Gastrointestinal infarctions (HP:0005244) | 2.21063459 |
| 60 | Pancreatic fibrosis (HP:0100732) | 2.18494703 |
| 61 | Large for gestational age (HP:0001520) | 2.18202300 |
| 62 | Hypergammaglobulinemia (HP:0010702) | 2.16837476 |
| 63 | Medial flaring of the eyebrow (HP:0010747) | 2.15565603 |
| 64 | Aplastic anemia (HP:0001915) | 2.11924809 |
| 65 | Abnormality of alanine metabolism (HP:0010916) | 2.11923320 |
| 66 | Hyperalaninemia (HP:0003348) | 2.11923320 |
| 67 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.11923320 |
| 68 | Lipid accumulation in hepatocytes (HP:0006561) | 2.10923464 |
| 69 | Hypoproteinemia (HP:0003075) | 2.09918178 |
| 70 | Recurrent skin infections (HP:0001581) | 2.09380490 |
| 71 | Renal cortical cysts (HP:0000803) | 2.08975077 |
| 72 | Prostate neoplasm (HP:0100787) | 2.07867205 |
| 73 | Attenuation of retinal blood vessels (HP:0007843) | 2.07598912 |
| 74 | Keratoconjunctivitis sicca (HP:0001097) | 2.07515042 |
| 75 | Abnormality of the pleura (HP:0002103) | 2.06825439 |
| 76 | Abnormality of midbrain morphology (HP:0002418) | 2.05840555 |
| 77 | Molar tooth sign on MRI (HP:0002419) | 2.05840555 |
| 78 | Increased CSF lactate (HP:0002490) | 2.04002884 |
| 79 | Methylmalonic acidemia (HP:0002912) | 2.02706020 |
| 80 | Abnormality of the renal cortex (HP:0011035) | 2.02671126 |
| 81 | Progressive microcephaly (HP:0000253) | 2.02644550 |
| 82 | Agammaglobulinemia (HP:0004432) | 2.00773979 |
| 83 | Arterial thrombosis (HP:0004420) | 2.00485063 |
| 84 | Gangrene (HP:0100758) | 2.00079753 |
| 85 | Neutropenia (HP:0001875) | 1.99823971 |
| 86 | Abnormality of the renal medulla (HP:0100957) | 1.99754177 |
| 87 | Keratoconjunctivitis (HP:0001096) | 1.99243552 |
| 88 | Vacuolated lymphocytes (HP:0001922) | 1.93178140 |
| 89 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.90437689 |
| 90 | Pulmonary fibrosis (HP:0002206) | 1.89522103 |
| 91 | Chronic diarrhea (HP:0002028) | 1.89262445 |
| 92 | Hepatic necrosis (HP:0002605) | 1.89066636 |
| 93 | Chest pain (HP:0100749) | 1.88651433 |
| 94 | IgM deficiency (HP:0002850) | 1.87680185 |
| 95 | Papilledema (HP:0001085) | 1.87614955 |
| 96 | IgA deficiency (HP:0002720) | 1.84656242 |
| 97 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.83213527 |
| 98 | Chronic otitis media (HP:0000389) | 1.82509888 |
| 99 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 1.81431262 |
| 100 | Acute necrotizing encephalopathy (HP:0006965) | 1.81306559 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 4.30769772 |
| 2 | TLK1 | 3.22280794 |
| 3 | TAOK3 | 3.14718535 |
| 4 | MAP4K1 | 2.78568573 |
| 5 | KIT | 2.70731646 |
| 6 | VRK2 | 2.25091126 |
| 7 | NUAK1 | 2.20563455 |
| 8 | IRAK4 | 2.19838734 |
| 9 | MAP3K14 | 2.11026943 |
| 10 | FRK | 2.08047436 |
| 11 | GRK6 | 2.07847777 |
| 12 | ZAK | 2.02326683 |
| 13 | MST4 | 1.85798509 |
| 14 | TEC | 1.85427940 |
| 15 | ADRBK2 | 1.84340342 |
| 16 | SYK | 1.83417304 |
| 17 | FES | 1.82445921 |
| 18 | IKBKB | 1.67042734 |
| 19 | RIPK4 | 1.63505085 |
| 20 | IKBKE | 1.62231672 |
| 21 | EIF2AK3 | 1.58533731 |
| 22 | GRK5 | 1.57341274 |
| 23 | GRK1 | 1.54894514 |
| 24 | BLK | 1.44246390 |
| 25 | BMPR2 | 1.43358385 |
| 26 | TYK2 | 1.42422825 |
| 27 | ITK | 1.42023388 |
| 28 | KDR | 1.38557339 |
| 29 | JAK1 | 1.37889204 |
| 30 | EIF2AK1 | 1.35298239 |
| 31 | VRK1 | 1.33020132 |
| 32 | MAP4K2 | 1.32948472 |
| 33 | JAK3 | 1.31609543 |
| 34 | LYN | 1.30514620 |
| 35 | GRK7 | 1.28100663 |
| 36 | PRKCQ | 1.24474267 |
| 37 | BCKDK | 1.23437486 |
| 38 | LCK | 1.20460190 |
| 39 | EIF2AK2 | 1.17087339 |
| 40 | TNK2 | 1.15677981 |
| 41 | TESK2 | 1.15551685 |
| 42 | MATK | 1.15220424 |
| 43 | BTK | 1.13509656 |
| 44 | ZAP70 | 1.11720350 |
| 45 | TBK1 | 1.10751541 |
| 46 | PTK2B | 1.06570500 |
| 47 | CSK | 1.06047193 |
| 48 | PIK3CG | 1.04677372 |
| 49 | DAPK2 | 1.02433084 |
| 50 | PINK1 | 0.98804461 |
| 51 | TRIM28 | 0.98477517 |
| 52 | MAP3K12 | 0.97668327 |
| 53 | CSF1R | 0.95188302 |
| 54 | HCK | 0.92001020 |
| 55 | CDC7 | 0.87493939 |
| 56 | OXSR1 | 0.86221081 |
| 57 | ADRBK1 | 0.85558345 |
| 58 | BCR | 0.84830023 |
| 59 | PIM2 | 0.81982775 |
| 60 | PIM1 | 0.81070270 |
| 61 | MAPKAPK3 | 0.80150605 |
| 62 | ATR | 0.78752374 |
| 63 | CAMKK2 | 0.75832431 |
| 64 | MAP2K6 | 0.70144039 |
| 65 | NME1 | 0.68568772 |
| 66 | RPS6KA5 | 0.68378947 |
| 67 | CLK1 | 0.67802367 |
| 68 | PLK2 | 0.66373095 |
| 69 | TGFBR2 | 0.66169707 |
| 70 | CHUK | 0.62474851 |
| 71 | PLK3 | 0.61346770 |
| 72 | MARK3 | 0.60050163 |
| 73 | BMPR1B | 0.56012635 |
| 74 | ACVR1B | 0.53724635 |
| 75 | IRAK1 | 0.53144506 |
| 76 | ABL1 | 0.52412517 |
| 77 | WNK3 | 0.52263672 |
| 78 | STK10 | 0.47740216 |
| 79 | AURKB | 0.46131240 |
| 80 | JAK2 | 0.43058338 |
| 81 | INSRR | 0.41357841 |
| 82 | CDK4 | 0.41174343 |
| 83 | CSNK1G2 | 0.40506896 |
| 84 | PRKCI | 0.39396750 |
| 85 | IGF1R | 0.38049848 |
| 86 | NME2 | 0.37191775 |
| 87 | ERBB3 | 0.37117303 |
| 88 | EPHA3 | 0.36718753 |
| 89 | CCNB1 | 0.35727735 |
| 90 | MAP3K5 | 0.35444600 |
| 91 | MAP2K3 | 0.35272902 |
| 92 | MAP3K11 | 0.35125374 |
| 93 | CSNK2A1 | 0.34262895 |
| 94 | PRKCD | 0.33523328 |
| 95 | PRKCH | 0.33003186 |
| 96 | PLK4 | 0.30730743 |
| 97 | DYRK1B | 0.30517820 |
| 98 | DAPK1 | 0.28066599 |
| 99 | CSNK2A2 | 0.27056581 |
| 100 | TRPM7 | 0.26089871 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.69561325 |
| 2 | Asthma_Homo sapiens_hsa05310 | 3.43352023 |
| 3 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.13869029 |
| 4 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.12890201 |
| 5 | Allograft rejection_Homo sapiens_hsa05330 | 3.04852729 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.89970940 |
| 7 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.68881605 |
| 8 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.62202253 |
| 9 | Proteasome_Homo sapiens_hsa03050 | 2.49335514 |
| 10 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.48945285 |
| 11 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.18345318 |
| 12 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.00075379 |
| 13 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.99488262 |
| 14 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.94385899 |
| 15 | Mismatch repair_Homo sapiens_hsa03430 | 1.91803188 |
| 16 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.90368623 |
| 17 | Leishmaniasis_Homo sapiens_hsa05140 | 1.82937258 |
| 18 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.82917217 |
| 19 | Homologous recombination_Homo sapiens_hsa03440 | 1.80161126 |
| 20 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.79702642 |
| 21 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.64547321 |
| 22 | Protein export_Homo sapiens_hsa03060 | 1.63323693 |
| 23 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.61426364 |
| 24 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.57747810 |
| 25 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.57654561 |
| 26 | Parkinsons disease_Homo sapiens_hsa05012 | 1.48860698 |
| 27 | DNA replication_Homo sapiens_hsa03030 | 1.48417970 |
| 28 | Base excision repair_Homo sapiens_hsa03410 | 1.41817360 |
| 29 | Ribosome_Homo sapiens_hsa03010 | 1.37411703 |
| 30 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.33279179 |
| 31 | Legionellosis_Homo sapiens_hsa05134 | 1.27202954 |
| 32 | Measles_Homo sapiens_hsa05162 | 1.26144706 |
| 33 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.24366029 |
| 34 | RNA polymerase_Homo sapiens_hsa03020 | 1.24091488 |
| 35 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.22314250 |
| 36 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.17722698 |
| 37 | Malaria_Homo sapiens_hsa05144 | 1.14998614 |
| 38 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.14378023 |
| 39 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.12387547 |
| 40 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.09611005 |
| 41 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.08684512 |
| 42 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.03435796 |
| 43 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.01148701 |
| 44 | Phototransduction_Homo sapiens_hsa04744 | 1.00659904 |
| 45 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.00145706 |
| 46 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.97122318 |
| 47 | Basal transcription factors_Homo sapiens_hsa03022 | 0.93508133 |
| 48 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.93075126 |
| 49 | Tuberculosis_Homo sapiens_hsa05152 | 0.91090227 |
| 50 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.88877316 |
| 51 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.87978910 |
| 52 | Viral myocarditis_Homo sapiens_hsa05416 | 0.87762699 |
| 53 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.87559372 |
| 54 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.80579592 |
| 55 | RNA degradation_Homo sapiens_hsa03018 | 0.78263431 |
| 56 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.77794402 |
| 57 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.76880133 |
| 58 | Alzheimers disease_Homo sapiens_hsa05010 | 0.76095389 |
| 59 | Peroxisome_Homo sapiens_hsa04146 | 0.75510375 |
| 60 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.73390140 |
| 61 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.69736875 |
| 62 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.68403697 |
| 63 | Huntingtons disease_Homo sapiens_hsa05016 | 0.67924152 |
| 64 | Influenza A_Homo sapiens_hsa05164 | 0.65887362 |
| 65 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.64620445 |
| 66 | Spliceosome_Homo sapiens_hsa03040 | 0.63934591 |
| 67 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.61779261 |
| 68 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.61636593 |
| 69 | Purine metabolism_Homo sapiens_hsa00230 | 0.60403129 |
| 70 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.57858012 |
| 71 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.55603034 |
| 72 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.53625251 |
| 73 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.51892287 |
| 74 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.51466053 |
| 75 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.51024993 |
| 76 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.49805589 |
| 77 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.49687905 |
| 78 | Phagosome_Homo sapiens_hsa04145 | 0.48446695 |
| 79 | Lysosome_Homo sapiens_hsa04142 | 0.47473895 |
| 80 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.45981317 |
| 81 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.44113480 |
| 82 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.43903469 |
| 83 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.43186645 |
| 84 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.42971039 |
| 85 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.42138249 |
| 86 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.41017445 |
| 87 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.37795542 |
| 88 | HTLV-I infection_Homo sapiens_hsa05166 | 0.37117231 |
| 89 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.35999398 |
| 90 | Pertussis_Homo sapiens_hsa05133 | 0.34976957 |
| 91 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.33268719 |
| 92 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.30380994 |
| 93 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.27309070 |
| 94 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.27060885 |
| 95 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.26802296 |
| 96 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.25659006 |
| 97 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.25569076 |
| 98 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.24777057 |
| 99 | Shigellosis_Homo sapiens_hsa05131 | 0.21804903 |
| 100 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.21087107 |

