

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | cytidine metabolic process (GO:0046087) | 7.84923962 |
| 2 | cytidine catabolic process (GO:0006216) | 7.84923962 |
| 3 | cytidine deamination (GO:0009972) | 7.84923962 |
| 4 | DNA deamination (GO:0045006) | 7.40677616 |
| 5 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 6.87893933 |
| 6 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 6.59198303 |
| 7 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 5.35236605 |
| 8 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 5.35236605 |
| 9 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.63019457 |
| 10 | ATP synthesis coupled proton transport (GO:0015986) | 4.62251805 |
| 11 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.62251805 |
| 12 | chaperone-mediated protein transport (GO:0072321) | 4.31764966 |
| 13 | behavioral response to nicotine (GO:0035095) | 4.16617670 |
| 14 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.16150361 |
| 15 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.14353448 |
| 16 | protein neddylation (GO:0045116) | 4.08523252 |
| 17 | respiratory electron transport chain (GO:0022904) | 3.98638957 |
| 18 | protein complex biogenesis (GO:0070271) | 3.96220582 |
| 19 | electron transport chain (GO:0022900) | 3.91721528 |
| 20 | proteasome assembly (GO:0043248) | 3.73693731 |
| 21 | adaptation of signaling pathway (GO:0023058) | 3.71775674 |
| 22 | protein-cofactor linkage (GO:0018065) | 3.69571679 |
| 23 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.68931563 |
| 24 | NADH dehydrogenase complex assembly (GO:0010257) | 3.68931563 |
| 25 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.68931563 |
| 26 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.61300405 |
| 27 | pyrimidine nucleoside catabolic process (GO:0046135) | 3.57825183 |
| 28 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.48795369 |
| 29 | inner mitochondrial membrane organization (GO:0007007) | 3.47215224 |
| 30 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.42697814 |
| 31 | positive regulation of B cell differentiation (GO:0045579) | 3.40870658 |
| 32 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.40576699 |
| 33 | positive regulation of interleukin-8 secretion (GO:2000484) | 3.39802511 |
| 34 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.35410122 |
| 35 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.31340070 |
| 36 | cytolysis (GO:0019835) | 3.30029867 |
| 37 | purine nucleotide salvage (GO:0032261) | 3.27217772 |
| 38 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.25069452 |
| 39 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.23065446 |
| 40 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.23065446 |
| 41 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.22417016 |
| 42 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.22417016 |
| 43 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.22417016 |
| 44 | adenosine metabolic process (GO:0046085) | 3.16363756 |
| 45 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.12846518 |
| 46 | pyrimidine-containing compound catabolic process (GO:0072529) | 3.11595859 |
| 47 | hydrogen ion transmembrane transport (GO:1902600) | 3.08287158 |
| 48 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.04857379 |
| 49 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.04857379 |
| 50 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.04146492 |
| 51 | ribosomal small subunit assembly (GO:0000028) | 3.03359928 |
| 52 | proton transport (GO:0015992) | 3.01820979 |
| 53 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.01762418 |
| 54 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.01635632 |
| 55 | chromatin remodeling at centromere (GO:0031055) | 2.98646998 |
| 56 | respiratory chain complex IV assembly (GO:0008535) | 2.96215561 |
| 57 | hydrogen transport (GO:0006818) | 2.95997369 |
| 58 | CENP-A containing nucleosome assembly (GO:0034080) | 2.95938068 |
| 59 | DNA demethylation (GO:0080111) | 2.94907344 |
| 60 | DNA double-strand break processing (GO:0000729) | 2.94170958 |
| 61 | positive regulation of T cell apoptotic process (GO:0070234) | 2.91241206 |
| 62 | cytochrome complex assembly (GO:0017004) | 2.91187345 |
| 63 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.90214390 |
| 64 | negative regulation by host of viral transcription (GO:0043922) | 2.88253781 |
| 65 | negative regulation of ligase activity (GO:0051352) | 2.86702122 |
| 66 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.86702122 |
| 67 | sequestering of actin monomers (GO:0042989) | 2.85454654 |
| 68 | pseudouridine synthesis (GO:0001522) | 2.85379423 |
| 69 | T cell migration (GO:0072678) | 2.83542630 |
| 70 | metallo-sulfur cluster assembly (GO:0031163) | 2.83023890 |
| 71 | iron-sulfur cluster assembly (GO:0016226) | 2.83023890 |
| 72 | tRNA processing (GO:0008033) | 2.82758665 |
| 73 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.82039886 |
| 74 | pyrimidine ribonucleoside metabolic process (GO:0046131) | 2.81850452 |
| 75 | eosinophil chemotaxis (GO:0048245) | 2.80517428 |
| 76 | regulation of chronic inflammatory response (GO:0002676) | 2.80448225 |
| 77 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 2.78452363 |
| 78 | maturation of SSU-rRNA (GO:0030490) | 2.75762933 |
| 79 | rRNA modification (GO:0000154) | 2.70458349 |
| 80 | regulation of interleukin-8 secretion (GO:2000482) | 2.68759838 |
| 81 | DNA dealkylation (GO:0035510) | 2.66874392 |
| 82 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.66550323 |
| 83 | regulation of cellular amine metabolic process (GO:0033238) | 2.64573027 |
| 84 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.64515591 |
| 85 | piRNA metabolic process (GO:0034587) | 2.63422676 |
| 86 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.63102459 |
| 87 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.63064559 |
| 88 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.62293834 |
| 89 | GTP biosynthetic process (GO:0006183) | 2.60831571 |
| 90 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 2.60335396 |
| 91 | platelet dense granule organization (GO:0060155) | 2.60293532 |
| 92 | positive regulation of cell cycle arrest (GO:0071158) | 2.60172423 |
| 93 | kynurenine metabolic process (GO:0070189) | 2.60110748 |
| 94 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.58858987 |
| 95 | purine-containing compound salvage (GO:0043101) | 2.58495367 |
| 96 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.58139419 |
| 97 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.56413527 |
| 98 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.55091870 |
| 99 | eosinophil migration (GO:0072677) | 2.53131750 |
| 100 | sulfur amino acid catabolic process (GO:0000098) | 2.52132164 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.98301890 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.94545671 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.82523459 |
| 4 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.47789684 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.21934495 |
| 6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.18265069 |
| 7 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.12232323 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.02275679 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.90564106 |
| 10 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.77004673 |
| 11 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.74960014 |
| 12 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.70125600 |
| 13 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.42326087 |
| 14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.27100159 |
| 15 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.25983524 |
| 16 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.23072736 |
| 17 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.22116967 |
| 18 | VDR_22108803_ChIP-Seq_LS180_Human | 2.17626611 |
| 19 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.10923275 |
| 20 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.07987695 |
| 21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.00972698 |
| 22 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.99308085 |
| 23 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.82251712 |
| 24 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.76115545 |
| 25 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.63976510 |
| 26 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.60699403 |
| 27 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.52506352 |
| 28 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.48939787 |
| 29 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.46958607 |
| 30 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.46793262 |
| 31 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.44759324 |
| 32 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.41694078 |
| 33 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.40588498 |
| 34 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.39060313 |
| 35 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.38976831 |
| 36 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.38202232 |
| 37 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.38157150 |
| 38 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.36552051 |
| 39 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.34968680 |
| 40 | NCOR_22424771_ChIP-Seq_293T_Human | 1.34485346 |
| 41 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.34226708 |
| 42 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.33222223 |
| 43 | GATA3_26560356_Chip-Seq_TH2_Human | 1.27812683 |
| 44 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.26494818 |
| 45 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.26106368 |
| 46 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.25067913 |
| 47 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.24815523 |
| 48 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.24582747 |
| 49 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.24548070 |
| 50 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.24128687 |
| 51 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.19914902 |
| 52 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.19150108 |
| 53 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.18147329 |
| 54 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.15877764 |
| 55 | MYB_26560356_Chip-Seq_TH2_Human | 1.15306849 |
| 56 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.15050541 |
| 57 | EWS_26573619_Chip-Seq_HEK293_Human | 1.12758020 |
| 58 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.12174536 |
| 59 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.11989497 |
| 60 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.11915422 |
| 61 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.10850933 |
| 62 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.10850933 |
| 63 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.09932894 |
| 64 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.09369703 |
| 65 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.09154509 |
| 66 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.08787242 |
| 67 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.08362947 |
| 68 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.07557367 |
| 69 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.06326036 |
| 70 | AR_20517297_ChIP-Seq_VCAP_Human | 1.04364888 |
| 71 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.03788134 |
| 72 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.03458843 |
| 73 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.02343101 |
| 74 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.01617835 |
| 75 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.00861900 |
| 76 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.00436274 |
| 77 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.00407199 |
| 78 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.00299893 |
| 79 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.99513523 |
| 80 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.99513523 |
| 81 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.98974725 |
| 82 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.96905057 |
| 83 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.95387684 |
| 84 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.94800482 |
| 85 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.93646136 |
| 86 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.93646136 |
| 87 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.92794273 |
| 88 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.92442369 |
| 89 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.92250862 |
| 90 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.90725048 |
| 91 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.90118756 |
| 92 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.89354533 |
| 93 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.87926203 |
| 94 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.87906489 |
| 95 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.87658570 |
| 96 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.87319829 |
| 97 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.87121746 |
| 98 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.86451632 |
| 99 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.86445005 |
| 100 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.86065868 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 4.12028707 |
| 2 | MP0005671_abnormal_response_to | 4.00567155 |
| 3 | MP0004147_increased_porphyrin_level | 3.69428640 |
| 4 | MP0008877_abnormal_DNA_methylation | 2.52416673 |
| 5 | MP0002736_abnormal_nociception_after | 2.26899711 |
| 6 | MP0003806_abnormal_nucleotide_metabolis | 2.21298769 |
| 7 | MP0008872_abnormal_physiological_respon | 2.12541048 |
| 8 | MP0003646_muscle_fatigue | 2.09737594 |
| 9 | MP0009785_altered_susceptibility_to | 2.08451746 |
| 10 | MP0006292_abnormal_olfactory_placode | 2.05898621 |
| 11 | MP0002095_abnormal_skin_pigmentation | 2.03838973 |
| 12 | MP0009333_abnormal_splenocyte_physiolog | 2.01797703 |
| 13 | MP0001968_abnormal_touch/_nociception | 1.92836747 |
| 14 | MP0001873_stomach_inflammation | 1.88202572 |
| 15 | MP0005075_abnormal_melanosome_morpholog | 1.85025392 |
| 16 | MP0005360_urolithiasis | 1.84393680 |
| 17 | MP0001835_abnormal_antigen_presentation | 1.84283435 |
| 18 | MP0002102_abnormal_ear_morphology | 1.84219996 |
| 19 | MP0005551_abnormal_eye_electrophysiolog | 1.83382367 |
| 20 | MP0003763_abnormal_thymus_physiology | 1.77299610 |
| 21 | MP0000372_irregular_coat_pigmentation | 1.77103286 |
| 22 | MP0008995_early_reproductive_senescence | 1.72565830 |
| 23 | MP0005646_abnormal_pituitary_gland | 1.69520292 |
| 24 | MP0002876_abnormal_thyroid_physiology | 1.67470256 |
| 25 | MP0004885_abnormal_endolymph | 1.67435298 |
| 26 | MP0003786_premature_aging | 1.64885640 |
| 27 | MP0004742_abnormal_vestibular_system | 1.63311458 |
| 28 | MP0005645_abnormal_hypothalamus_physiol | 1.57450535 |
| 29 | MP0001919_abnormal_reproductive_system | 1.55292717 |
| 30 | MP0005389_reproductive_system_phenotype | 1.54064929 |
| 31 | MP0008875_abnormal_xenobiotic_pharmacok | 1.46745102 |
| 32 | MP0004145_abnormal_muscle_electrophysio | 1.44730297 |
| 33 | MP0002653_abnormal_ependyma_morphology | 1.43872398 |
| 34 | MP0001485_abnormal_pinna_reflex | 1.41465807 |
| 35 | MP0001800_abnormal_humoral_immune | 1.41459193 |
| 36 | MP0001905_abnormal_dopamine_level | 1.38380735 |
| 37 | MP0005410_abnormal_fertilization | 1.38061436 |
| 38 | MP0001188_hyperpigmentation | 1.36210327 |
| 39 | MP0003878_abnormal_ear_physiology | 1.36029568 |
| 40 | MP0005377_hearing/vestibular/ear_phenot | 1.36029568 |
| 41 | MP0005174_abnormal_tail_pigmentation | 1.30395163 |
| 42 | MP0002938_white_spotting | 1.30366717 |
| 43 | MP0002160_abnormal_reproductive_system | 1.30183303 |
| 44 | MP0002138_abnormal_hepatobiliary_system | 1.29829300 |
| 45 | MP0005670_abnormal_white_adipose | 1.27325205 |
| 46 | MP0009745_abnormal_behavioral_response | 1.26951282 |
| 47 | MP0002638_abnormal_pupillary_reflex | 1.23906676 |
| 48 | MP0005000_abnormal_immune_tolerance | 1.21433480 |
| 49 | MP0003011_delayed_dark_adaptation | 1.18547107 |
| 50 | MP0006082_CNS_inflammation | 1.17109535 |
| 51 | MP0002277_abnormal_respiratory_mucosa | 1.15389371 |
| 52 | MP0005332_abnormal_amino_acid | 1.13574268 |
| 53 | MP0004142_abnormal_muscle_tone | 1.12209604 |
| 54 | MP0002148_abnormal_hypersensitivity_rea | 1.12022696 |
| 55 | MP0001486_abnormal_startle_reflex | 1.11764386 |
| 56 | MP0002006_tumorigenesis | 1.11111086 |
| 57 | MP0002166_altered_tumor_susceptibility | 1.11072687 |
| 58 | MP0002420_abnormal_adaptive_immunity | 1.09974039 |
| 59 | MP0001790_abnormal_immune_system | 1.09954333 |
| 60 | MP0005387_immune_system_phenotype | 1.09954333 |
| 61 | MP0002837_dystrophic_cardiac_calcinosis | 1.07091886 |
| 62 | MP0005025_abnormal_response_to | 1.05249233 |
| 63 | MP0003195_calcinosis | 1.05043014 |
| 64 | MP0002272_abnormal_nervous_system | 1.04584374 |
| 65 | MP0006036_abnormal_mitochondrial_physio | 1.03030602 |
| 66 | MP0003186_abnormal_redox_activity | 1.02870368 |
| 67 | MP0001819_abnormal_immune_cell | 1.02451437 |
| 68 | MP0001542_abnormal_bone_strength | 1.01873147 |
| 69 | MP0002723_abnormal_immune_serum | 1.01731155 |
| 70 | MP0005084_abnormal_gallbladder_morpholo | 1.00792904 |
| 71 | MP0003866_abnormal_defecation | 0.99884547 |
| 72 | MP0003183_abnormal_peptide_metabolism | 0.98081955 |
| 73 | MP0005636_abnormal_mineral_homeostasis | 0.95707230 |
| 74 | MP0003693_abnormal_embryo_hatching | 0.95087492 |
| 75 | MP0003787_abnormal_imprinting | 0.94932149 |
| 76 | MP0006072_abnormal_retinal_apoptosis | 0.92369121 |
| 77 | MP0000569_abnormal_digit_pigmentation | 0.88929166 |
| 78 | MP0003567_abnormal_fetal_cardiomyocyte | 0.87078528 |
| 79 | MP0001963_abnormal_hearing_physiology | 0.86822051 |
| 80 | MP0000703_abnormal_thymus_morphology | 0.86680500 |
| 81 | MP0000516_abnormal_urinary_system | 0.86492377 |
| 82 | MP0005367_renal/urinary_system_phenotyp | 0.86492377 |
| 83 | MP0005253_abnormal_eye_physiology | 0.85833877 |
| 84 | MP0002210_abnormal_sex_determination | 0.85329176 |
| 85 | MP0000015_abnormal_ear_pigmentation | 0.84428127 |
| 86 | MP0009765_abnormal_xenobiotic_induced | 0.83705733 |
| 87 | MP0000026_abnormal_inner_ear | 0.83267301 |
| 88 | MP0000716_abnormal_immune_system | 0.80908482 |
| 89 | MP0003880_abnormal_central_pattern | 0.80684215 |
| 90 | MP0009643_abnormal_urine_homeostasis | 0.80122906 |
| 91 | MP0001986_abnormal_taste_sensitivity | 0.79665991 |
| 92 | MP0002452_abnormal_antigen_presenting | 0.79610618 |
| 93 | MP0002733_abnormal_thermal_nociception | 0.79521021 |
| 94 | MP0001502_abnormal_circadian_rhythm | 0.78739449 |
| 95 | MP0006276_abnormal_autonomic_nervous | 0.78211024 |
| 96 | MP0001929_abnormal_gametogenesis | 0.77762536 |
| 97 | MP0000685_abnormal_immune_system | 0.76204626 |
| 98 | MP0008007_abnormal_cellular_replicative | 0.75503889 |
| 99 | MP0002398_abnormal_bone_marrow | 0.73814038 |
| 100 | MP0002234_abnormal_pharynx_morphology | 0.73668296 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aplastic anemia (HP:0001915) | 4.85479792 |
| 2 | Abnormality of alanine metabolism (HP:0010916) | 4.60035704 |
| 3 | Hyperalaninemia (HP:0003348) | 4.60035704 |
| 4 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 4.60035704 |
| 5 | Acute necrotizing encephalopathy (HP:0006965) | 4.48181491 |
| 6 | Mitochondrial inheritance (HP:0001427) | 4.16725575 |
| 7 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.98896188 |
| 8 | Acute encephalopathy (HP:0006846) | 3.71618069 |
| 9 | Increased CSF lactate (HP:0002490) | 3.68770214 |
| 10 | Progressive macrocephaly (HP:0004481) | 3.67941404 |
| 11 | Hepatocellular necrosis (HP:0001404) | 3.62715792 |
| 12 | Constricted visual fields (HP:0001133) | 3.40029777 |
| 13 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 3.30802574 |
| 14 | Hypoproteinemia (HP:0003075) | 3.25534834 |
| 15 | Hepatic necrosis (HP:0002605) | 3.04055753 |
| 16 | Cerebral edema (HP:0002181) | 3.00746472 |
| 17 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.94018910 |
| 18 | Increased hepatocellular lipid droplets (HP:0006565) | 2.92491643 |
| 19 | Abnormality of midbrain morphology (HP:0002418) | 2.85041711 |
| 20 | Molar tooth sign on MRI (HP:0002419) | 2.85041711 |
| 21 | IgG deficiency (HP:0004315) | 2.79601312 |
| 22 | Renal Fanconi syndrome (HP:0001994) | 2.79114435 |
| 23 | Increased serum lactate (HP:0002151) | 2.74687820 |
| 24 | Pancytopenia (HP:0001876) | 2.68207454 |
| 25 | Autoimmune hemolytic anemia (HP:0001890) | 2.65944160 |
| 26 | Lactic acidosis (HP:0003128) | 2.62256113 |
| 27 | Lipid accumulation in hepatocytes (HP:0006561) | 2.61776571 |
| 28 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.61771404 |
| 29 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.61771404 |
| 30 | Lethargy (HP:0001254) | 2.55120799 |
| 31 | Abnormality of the prostate (HP:0008775) | 2.54050117 |
| 32 | Congenital stationary night blindness (HP:0007642) | 2.52231912 |
| 33 | 3-Methylglutaconic aciduria (HP:0003535) | 2.48044164 |
| 34 | Reticulocytopenia (HP:0001896) | 2.47769566 |
| 35 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.47297454 |
| 36 | T lymphocytopenia (HP:0005403) | 2.47020608 |
| 37 | Abnormality of serum amino acid levels (HP:0003112) | 2.44288586 |
| 38 | Optic disc pallor (HP:0000543) | 2.40749138 |
| 39 | Pendular nystagmus (HP:0012043) | 2.38915354 |
| 40 | Congenital sensorineural hearing impairment (HP:0008527) | 2.36415527 |
| 41 | Abnormality of T cell number (HP:0011839) | 2.34077310 |
| 42 | Hyperglycinemia (HP:0002154) | 2.33985373 |
| 43 | Pancreatic fibrosis (HP:0100732) | 2.32568941 |
| 44 | Abolished electroretinogram (ERG) (HP:0000550) | 2.31930658 |
| 45 | Pancreatic cysts (HP:0001737) | 2.28741856 |
| 46 | Methylmalonic acidemia (HP:0002912) | 2.23375147 |
| 47 | Abnormality of B cell number (HP:0010975) | 2.23028261 |
| 48 | Increased intramyocellular lipid droplets (HP:0012240) | 2.22380000 |
| 49 | Absent thumb (HP:0009777) | 2.21093738 |
| 50 | Birth length less than 3rd percentile (HP:0003561) | 2.19940548 |
| 51 | Leukodystrophy (HP:0002415) | 2.18055611 |
| 52 | Chronic diarrhea (HP:0002028) | 2.16629503 |
| 53 | True hermaphroditism (HP:0010459) | 2.13256222 |
| 54 | Polydipsia (HP:0001959) | 2.10448217 |
| 55 | Abnormal drinking behavior (HP:0030082) | 2.10448217 |
| 56 | Abnormality of T cells (HP:0002843) | 2.07555178 |
| 57 | Attenuation of retinal blood vessels (HP:0007843) | 2.07433690 |
| 58 | Rib fusion (HP:0000902) | 2.03177060 |
| 59 | Methylmalonic aciduria (HP:0012120) | 2.03040130 |
| 60 | Medial flaring of the eyebrow (HP:0010747) | 2.02730574 |
| 61 | B lymphocytopenia (HP:0010976) | 2.02290403 |
| 62 | Stomatitis (HP:0010280) | 1.99984123 |
| 63 | Neutropenia (HP:0001875) | 1.99730545 |
| 64 | Supernumerary spleens (HP:0009799) | 1.99628260 |
| 65 | Severe combined immunodeficiency (HP:0004430) | 1.99502039 |
| 66 | Respiratory failure (HP:0002878) | 1.96883200 |
| 67 | Exercise intolerance (HP:0003546) | 1.96098739 |
| 68 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.93704608 |
| 69 | Abnormal albumin level (HP:0012116) | 1.90874877 |
| 70 | Hypoalbuminemia (HP:0003073) | 1.90874877 |
| 71 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.90453525 |
| 72 | Abnormality of the labia minora (HP:0012880) | 1.87813170 |
| 73 | Abnormal number of erythroid precursors (HP:0012131) | 1.86781696 |
| 74 | Generalized aminoaciduria (HP:0002909) | 1.86510332 |
| 75 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.85603152 |
| 76 | Glycosuria (HP:0003076) | 1.83595315 |
| 77 | Abnormality of urine glucose concentration (HP:0011016) | 1.83595315 |
| 78 | Poor speech (HP:0002465) | 1.83524082 |
| 79 | Macrocytic anemia (HP:0001972) | 1.81806890 |
| 80 | Colon cancer (HP:0003003) | 1.79162654 |
| 81 | Abnormality of the renal collecting system (HP:0004742) | 1.77533123 |
| 82 | Anencephaly (HP:0002323) | 1.76319698 |
| 83 | Hyperphosphaturia (HP:0003109) | 1.75701402 |
| 84 | Abnormality of the renal cortex (HP:0011035) | 1.75373754 |
| 85 | Exertional dyspnea (HP:0002875) | 1.73920732 |
| 86 | Increased IgM level (HP:0003496) | 1.72765834 |
| 87 | Polyuria (HP:0000103) | 1.72340654 |
| 88 | Decreased central vision (HP:0007663) | 1.71292482 |
| 89 | Increased corneal curvature (HP:0100692) | 1.69978658 |
| 90 | Keratoconus (HP:0000563) | 1.69978658 |
| 91 | Renal cortical cysts (HP:0000803) | 1.68197215 |
| 92 | Increased muscle lipid content (HP:0009058) | 1.67713441 |
| 93 | Abnormality of eosinophils (HP:0001879) | 1.67118351 |
| 94 | Septo-optic dysplasia (HP:0100842) | 1.65847582 |
| 95 | Abnormality of renal resorption (HP:0011038) | 1.65532140 |
| 96 | Meckel diverticulum (HP:0002245) | 1.65083704 |
| 97 | Anorexia (HP:0002039) | 1.65002682 |
| 98 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.64836672 |
| 99 | Tetany (HP:0001281) | 1.64365834 |
| 100 | Vomiting (HP:0002013) | 1.63798846 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 5.93847883 |
| 2 | KDR | 3.57854238 |
| 3 | VRK2 | 3.22690630 |
| 4 | MAP4K2 | 3.16028784 |
| 5 | MAP4K1 | 2.55561173 |
| 6 | NUAK1 | 2.29706822 |
| 7 | TLK1 | 2.14695292 |
| 8 | BCKDK | 1.87363628 |
| 9 | BMPR1B | 1.81763434 |
| 10 | TAOK3 | 1.80625252 |
| 11 | WNK4 | 1.80289857 |
| 12 | MAP3K11 | 1.79575695 |
| 13 | CDC7 | 1.77533611 |
| 14 | GRK1 | 1.77223247 |
| 15 | STK16 | 1.76440522 |
| 16 | MST4 | 1.75188715 |
| 17 | MAP3K12 | 1.73122291 |
| 18 | ZAK | 1.69157284 |
| 19 | VRK1 | 1.64684956 |
| 20 | NTRK2 | 1.60207549 |
| 21 | ADRBK2 | 1.54353554 |
| 22 | DYRK2 | 1.53043305 |
| 23 | ITK | 1.50956453 |
| 24 | STK39 | 1.47553224 |
| 25 | MAPK13 | 1.33244045 |
| 26 | OXSR1 | 1.31362632 |
| 27 | TESK2 | 1.29686531 |
| 28 | PINK1 | 1.25993810 |
| 29 | TEC | 1.25402008 |
| 30 | SYK | 1.24953172 |
| 31 | WNK3 | 1.23266713 |
| 32 | NEK1 | 1.14865495 |
| 33 | MAP2K7 | 1.11589539 |
| 34 | FRK | 1.10605071 |
| 35 | BUB1 | 1.06265613 |
| 36 | LIMK1 | 1.03411453 |
| 37 | TAF1 | 0.98452707 |
| 38 | PRKCQ | 0.95011479 |
| 39 | IKBKB | 0.92329197 |
| 40 | AURKA | 0.89338640 |
| 41 | MUSK | 0.88932997 |
| 42 | INSRR | 0.88429881 |
| 43 | BTK | 0.80355526 |
| 44 | NME1 | 0.79696819 |
| 45 | PLK2 | 0.79248742 |
| 46 | PLK3 | 0.74322627 |
| 47 | FES | 0.73746144 |
| 48 | CDK9 | 0.73130478 |
| 49 | PLK1 | 0.69058835 |
| 50 | MARK1 | 0.68961308 |
| 51 | ATR | 0.67571510 |
| 52 | CSK | 0.66704400 |
| 53 | GRK5 | 0.66350297 |
| 54 | PRKCG | 0.65192924 |
| 55 | GRK7 | 0.64906529 |
| 56 | MYLK | 0.64068814 |
| 57 | PLK4 | 0.63802954 |
| 58 | CSNK1A1 | 0.62532806 |
| 59 | LYN | 0.61694737 |
| 60 | ADRBK1 | 0.61497699 |
| 61 | CHEK2 | 0.60226108 |
| 62 | LCK | 0.57717767 |
| 63 | MKNK2 | 0.57270172 |
| 64 | CAMK2D | 0.57136194 |
| 65 | PIK3CA | 0.56660007 |
| 66 | PDK2 | 0.55412646 |
| 67 | SRPK1 | 0.55024632 |
| 68 | CAMK2A | 0.54857096 |
| 69 | ABL2 | 0.54254567 |
| 70 | CSNK2A1 | 0.52737468 |
| 71 | PRKACA | 0.52015322 |
| 72 | TYRO3 | 0.51969726 |
| 73 | PIM2 | 0.51937175 |
| 74 | TIE1 | 0.49917357 |
| 75 | IGF1R | 0.49322787 |
| 76 | JAK3 | 0.47959084 |
| 77 | CSNK1G3 | 0.46536404 |
| 78 | PRKCA | 0.46054723 |
| 79 | OBSCN | 0.45522925 |
| 80 | CDK19 | 0.44386248 |
| 81 | EIF2AK3 | 0.44044799 |
| 82 | DAPK3 | 0.43358626 |
| 83 | GRK6 | 0.39814677 |
| 84 | PBK | 0.39133223 |
| 85 | CSNK2A2 | 0.39038521 |
| 86 | CAMK1 | 0.37836486 |
| 87 | PRKCD | 0.36572058 |
| 88 | RPS6KA5 | 0.36072396 |
| 89 | PRKCE | 0.35640892 |
| 90 | EIF2AK2 | 0.35037188 |
| 91 | TESK1 | 0.34968006 |
| 92 | CAMK2G | 0.34602595 |
| 93 | CSNK1G2 | 0.33955879 |
| 94 | ACVR1B | 0.33927402 |
| 95 | NTRK1 | 0.33577945 |
| 96 | CASK | 0.33441895 |
| 97 | NTRK3 | 0.32982512 |
| 98 | PHKG1 | 0.32860410 |
| 99 | PHKG2 | 0.32860410 |
| 100 | AURKB | 0.32167943 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.65807275 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.24885613 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.46643563 |
| 4 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.11134432 |
| 5 | Ribosome_Homo sapiens_hsa03010 | 2.72929669 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.64247931 |
| 7 | Huntingtons disease_Homo sapiens_hsa05016 | 2.41377283 |
| 8 | RNA polymerase_Homo sapiens_hsa03020 | 2.31431164 |
| 9 | Homologous recombination_Homo sapiens_hsa03440 | 2.29192359 |
| 10 | Alzheimers disease_Homo sapiens_hsa05010 | 2.24255344 |
| 11 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.14152029 |
| 12 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.11236931 |
| 13 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.97517740 |
| 14 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.93125487 |
| 15 | Allograft rejection_Homo sapiens_hsa05330 | 1.72881511 |
| 16 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.72150166 |
| 17 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.67280205 |
| 18 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.64977940 |
| 19 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.47187634 |
| 20 | Sulfur relay system_Homo sapiens_hsa04122 | 1.46729062 |
| 21 | RNA degradation_Homo sapiens_hsa03018 | 1.41178515 |
| 22 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.40006175 |
| 23 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.39399354 |
| 24 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.39301298 |
| 25 | Phototransduction_Homo sapiens_hsa04744 | 1.31561257 |
| 26 | Nicotine addiction_Homo sapiens_hsa05033 | 1.31541423 |
| 27 | DNA replication_Homo sapiens_hsa03030 | 1.30665885 |
| 28 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.28660723 |
| 29 | Mismatch repair_Homo sapiens_hsa03430 | 1.27832163 |
| 30 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.25821586 |
| 31 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.25503587 |
| 32 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.25211995 |
| 33 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.23100645 |
| 34 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.21374551 |
| 35 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.20192213 |
| 36 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.15583594 |
| 37 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.14905552 |
| 38 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.14441521 |
| 39 | Spliceosome_Homo sapiens_hsa03040 | 1.13134175 |
| 40 | Asthma_Homo sapiens_hsa05310 | 1.08033543 |
| 41 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.06178993 |
| 42 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.03681895 |
| 43 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.02890073 |
| 44 | Basal transcription factors_Homo sapiens_hsa03022 | 1.02660096 |
| 45 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.00569138 |
| 46 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.97504150 |
| 47 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.96035693 |
| 48 | Purine metabolism_Homo sapiens_hsa00230 | 0.95190286 |
| 49 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.94924226 |
| 50 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.94487489 |
| 51 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.93721265 |
| 52 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.92134697 |
| 53 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.86848389 |
| 54 | Peroxisome_Homo sapiens_hsa04146 | 0.81679635 |
| 55 | Morphine addiction_Homo sapiens_hsa05032 | 0.79766588 |
| 56 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.78767219 |
| 57 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.76897373 |
| 58 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.74204806 |
| 59 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.73085626 |
| 60 | Metabolic pathways_Homo sapiens_hsa01100 | 0.71896295 |
| 61 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.70150767 |
| 62 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.68871883 |
| 63 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.68618295 |
| 64 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.68185958 |
| 65 | Olfactory transduction_Homo sapiens_hsa04740 | 0.62595367 |
| 66 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.61642787 |
| 67 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.61234484 |
| 68 | GABAergic synapse_Homo sapiens_hsa04727 | 0.60490499 |
| 69 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.60402162 |
| 70 | Retinol metabolism_Homo sapiens_hsa00830 | 0.59580843 |
| 71 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.58642625 |
| 72 | Taste transduction_Homo sapiens_hsa04742 | 0.58189213 |
| 73 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.56471642 |
| 74 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.54952200 |
| 75 | RNA transport_Homo sapiens_hsa03013 | 0.53443254 |
| 76 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.53150130 |
| 77 | Base excision repair_Homo sapiens_hsa03410 | 0.52030861 |
| 78 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.48422987 |
| 79 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.47545616 |
| 80 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.43379440 |
| 81 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.40809081 |
| 82 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.40313182 |
| 83 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.40068265 |
| 84 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.40038194 |
| 85 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.39566651 |
| 86 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.37043516 |
| 87 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.36162464 |
| 88 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.35717190 |
| 89 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.35062947 |
| 90 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.33760842 |
| 91 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.32655300 |
| 92 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.31593722 |
| 93 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.28661329 |
| 94 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.28605593 |
| 95 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.25974498 |
| 96 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.24367228 |
| 97 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.24017435 |
| 98 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.22508177 |
| 99 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.21640557 |
| 100 | Mineral absorption_Homo sapiens_hsa04978 | 0.20746492 |

