

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.14242507 |
| 2 | ATP synthesis coupled proton transport (GO:0015986) | 4.88955061 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.88955061 |
| 4 | chaperone-mediated protein transport (GO:0072321) | 4.83948556 |
| 5 | chromatin remodeling at centromere (GO:0031055) | 4.82039316 |
| 6 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.71127809 |
| 7 | maturation of SSU-rRNA (GO:0030490) | 4.63316950 |
| 8 | ribosomal small subunit biogenesis (GO:0042274) | 4.60665136 |
| 9 | CENP-A containing nucleosome assembly (GO:0034080) | 4.60443728 |
| 10 | protein neddylation (GO:0045116) | 4.58275198 |
| 11 | ribosomal small subunit assembly (GO:0000028) | 4.32731962 |
| 12 | viral transcription (GO:0019083) | 4.27958129 |
| 13 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 4.26155548 |
| 14 | translational termination (GO:0006415) | 4.24092388 |
| 15 | DNA replication checkpoint (GO:0000076) | 4.17930617 |
| 16 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.15567695 |
| 17 | protein complex biogenesis (GO:0070271) | 4.12685158 |
| 18 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.02445316 |
| 19 | kinetochore organization (GO:0051383) | 3.99041143 |
| 20 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.96980084 |
| 21 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.96980084 |
| 22 | NADH dehydrogenase complex assembly (GO:0010257) | 3.96980084 |
| 23 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.88897720 |
| 24 | histone exchange (GO:0043486) | 3.88046674 |
| 25 | cotranslational protein targeting to membrane (GO:0006613) | 3.87531888 |
| 26 | protein targeting to ER (GO:0045047) | 3.82694059 |
| 27 | respiratory electron transport chain (GO:0022904) | 3.81041875 |
| 28 | DNA deamination (GO:0045006) | 3.79523507 |
| 29 | electron transport chain (GO:0022900) | 3.77193730 |
| 30 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.74440455 |
| 31 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.73016940 |
| 32 | kinetochore assembly (GO:0051382) | 3.70204581 |
| 33 | ribosomal large subunit biogenesis (GO:0042273) | 3.69801026 |
| 34 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.66438214 |
| 35 | translational elongation (GO:0006414) | 3.65886604 |
| 36 | protein localization to endoplasmic reticulum (GO:0070972) | 3.59978582 |
| 37 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.59784696 |
| 38 | DNA replication-independent nucleosome organization (GO:0034724) | 3.59784696 |
| 39 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.52619823 |
| 40 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.48673792 |
| 41 | termination of RNA polymerase III transcription (GO:0006386) | 3.48673792 |
| 42 | regulation of mitochondrial translation (GO:0070129) | 3.46297853 |
| 43 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.42845756 |
| 44 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.37325286 |
| 45 | cellular component biogenesis (GO:0044085) | 3.36926469 |
| 46 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.36204691 |
| 47 | translation (GO:0006412) | 3.35520934 |
| 48 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.32112078 |
| 49 | replication fork processing (GO:0031297) | 3.30692595 |
| 50 | viral life cycle (GO:0019058) | 3.28963015 |
| 51 | cellular protein complex disassembly (GO:0043624) | 3.27551307 |
| 52 | translational initiation (GO:0006413) | 3.26826729 |
| 53 | rRNA processing (GO:0006364) | 3.25480563 |
| 54 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.25437853 |
| 55 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.22487702 |
| 56 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.20223429 |
| 57 | rRNA metabolic process (GO:0016072) | 3.19784144 |
| 58 | DNA double-strand break processing (GO:0000729) | 3.13681305 |
| 59 | protein-cofactor linkage (GO:0018065) | 3.11594085 |
| 60 | DNA strand elongation (GO:0022616) | 3.07543017 |
| 61 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.07040229 |
| 62 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.07040229 |
| 63 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.05207934 |
| 64 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.04859645 |
| 65 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.03867572 |
| 66 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.03599716 |
| 67 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.03599716 |
| 68 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.03076926 |
| 69 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.03076926 |
| 70 | cullin deneddylation (GO:0010388) | 3.02389894 |
| 71 | behavioral response to nicotine (GO:0035095) | 3.01158964 |
| 72 | base-excision repair, AP site formation (GO:0006285) | 3.00508749 |
| 73 | proteasome assembly (GO:0043248) | 3.00077286 |
| 74 | pseudouridine synthesis (GO:0001522) | 2.99109998 |
| 75 | maturation of 5.8S rRNA (GO:0000460) | 2.99038637 |
| 76 | respiratory chain complex IV assembly (GO:0008535) | 2.98743795 |
| 77 | cytochrome complex assembly (GO:0017004) | 2.97736480 |
| 78 | spliceosomal snRNP assembly (GO:0000387) | 2.96712383 |
| 79 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 2.94249002 |
| 80 | DNA damage response, detection of DNA damage (GO:0042769) | 2.92300716 |
| 81 | regulation of DNA endoreduplication (GO:0032875) | 2.92208242 |
| 82 | telomere maintenance via recombination (GO:0000722) | 2.91877979 |
| 83 | DNA ligation (GO:0006266) | 2.89409277 |
| 84 | protein targeting to mitochondrion (GO:0006626) | 2.89186014 |
| 85 | mitotic recombination (GO:0006312) | 2.88681497 |
| 86 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.88379619 |
| 87 | protein complex disassembly (GO:0043241) | 2.88165206 |
| 88 | macromolecular complex disassembly (GO:0032984) | 2.83088604 |
| 89 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.82881866 |
| 90 | protein deneddylation (GO:0000338) | 2.82597648 |
| 91 | establishment of integrated proviral latency (GO:0075713) | 2.80029375 |
| 92 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.78496395 |
| 93 | centriole replication (GO:0007099) | 2.77655292 |
| 94 | establishment of protein localization to mitochondrion (GO:0072655) | 2.76714905 |
| 95 | GTP biosynthetic process (GO:0006183) | 2.76360587 |
| 96 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.76050771 |
| 97 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.75245183 |
| 98 | negative regulation of ligase activity (GO:0051352) | 2.75245183 |
| 99 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 2.74976736 |
| 100 | tRNA processing (GO:0008033) | 2.72628778 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 5.05600065 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.82395983 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.22094697 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.97756472 |
| 5 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.89026783 |
| 6 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.35027121 |
| 7 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 3.28563242 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.17772052 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.10724864 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.95606281 |
| 11 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.76842153 |
| 12 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.71977763 |
| 13 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.67130417 |
| 14 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.66402330 |
| 15 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.55217819 |
| 16 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.44727442 |
| 17 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.42948410 |
| 18 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.42324761 |
| 19 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.42163499 |
| 20 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.39606889 |
| 21 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.38980865 |
| 22 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.27021882 |
| 23 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.24856102 |
| 24 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.19175647 |
| 25 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.15113946 |
| 26 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.14919277 |
| 27 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.93411930 |
| 28 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.93258033 |
| 29 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.91931505 |
| 30 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.87258660 |
| 31 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.81844766 |
| 32 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.81620473 |
| 33 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.79869627 |
| 34 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.78591724 |
| 35 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.78140747 |
| 36 | EWS_26573619_Chip-Seq_HEK293_Human | 1.73637593 |
| 37 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.72262728 |
| 38 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.71730787 |
| 39 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.71570638 |
| 40 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.69997894 |
| 41 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.66573602 |
| 42 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.64890021 |
| 43 | VDR_22108803_ChIP-Seq_LS180_Human | 1.64262832 |
| 44 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.62794329 |
| 45 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.61818951 |
| 46 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.57715871 |
| 47 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.55526543 |
| 48 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.54614796 |
| 49 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.45549472 |
| 50 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.44994910 |
| 51 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.44327841 |
| 52 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.43958346 |
| 53 | FUS_26573619_Chip-Seq_HEK293_Human | 1.42205267 |
| 54 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.41189553 |
| 55 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.39590426 |
| 56 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.37046337 |
| 57 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.36152712 |
| 58 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.21408182 |
| 59 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.20578371 |
| 60 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.12960810 |
| 61 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.12895282 |
| 62 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.12666486 |
| 63 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.11436164 |
| 64 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.10075860 |
| 65 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.09251735 |
| 66 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.09034367 |
| 67 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.08587990 |
| 68 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.06298391 |
| 69 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.05679989 |
| 70 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.02693675 |
| 71 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.02183174 |
| 72 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.02024565 |
| 73 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.00884228 |
| 74 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.98693261 |
| 75 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.95483969 |
| 76 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.94814066 |
| 77 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.94744431 |
| 78 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.94510471 |
| 79 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.93715083 |
| 80 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.91487692 |
| 81 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.89028864 |
| 82 | AR_21909140_ChIP-Seq_LNCAP_Human | 0.89000432 |
| 83 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.88856338 |
| 84 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.88752060 |
| 85 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.85636418 |
| 86 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.83541269 |
| 87 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.83498752 |
| 88 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.83498752 |
| 89 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.82623327 |
| 90 | P300_19829295_ChIP-Seq_ESCs_Human | 0.82321657 |
| 91 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.82285097 |
| 92 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.82182627 |
| 93 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.82061491 |
| 94 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.79958166 |
| 95 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.76219275 |
| 96 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.76024421 |
| 97 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.75793799 |
| 98 | NCOR_22424771_ChIP-Seq_293T_Human | 0.75712071 |
| 99 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.75638476 |
| 100 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.74409544 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 4.45480550 |
| 2 | MP0010094_abnormal_chromosome_stability | 3.45184181 |
| 3 | MP0008877_abnormal_DNA_methylation | 3.41974890 |
| 4 | MP0009379_abnormal_foot_pigmentation | 3.29582915 |
| 5 | MP0003693_abnormal_embryo_hatching | 3.14874847 |
| 6 | MP0008058_abnormal_DNA_repair | 3.12731548 |
| 7 | MP0003787_abnormal_imprinting | 2.82471596 |
| 8 | MP0003111_abnormal_nucleus_morphology | 2.32398790 |
| 9 | MP0004957_abnormal_blastocyst_morpholog | 2.27399345 |
| 10 | MP0003806_abnormal_nucleotide_metabolis | 2.04227416 |
| 11 | MP0003077_abnormal_cell_cycle | 2.02603985 |
| 12 | MP0008789_abnormal_olfactory_epithelium | 1.99445089 |
| 13 | MP0002938_white_spotting | 1.99166117 |
| 14 | MP0001293_anophthalmia | 1.97655527 |
| 15 | MP0006072_abnormal_retinal_apoptosis | 1.95409028 |
| 16 | MP0002736_abnormal_nociception_after | 1.84030304 |
| 17 | MP0003121_genomic_imprinting | 1.80795282 |
| 18 | MP0003718_maternal_effect | 1.75813730 |
| 19 | MP0008932_abnormal_embryonic_tissue | 1.75657169 |
| 20 | MP0001529_abnormal_vocalization | 1.75208379 |
| 21 | MP0002163_abnormal_gland_morphology | 1.74555850 |
| 22 | MP0002102_abnormal_ear_morphology | 1.72042854 |
| 23 | MP0005084_abnormal_gallbladder_morpholo | 1.67796427 |
| 24 | MP0005499_abnormal_olfactory_system | 1.56803509 |
| 25 | MP0005394_taste/olfaction_phenotype | 1.56803509 |
| 26 | MP0005645_abnormal_hypothalamus_physiol | 1.55905089 |
| 27 | MP0008872_abnormal_physiological_respon | 1.51941684 |
| 28 | MP0005646_abnormal_pituitary_gland | 1.49383727 |
| 29 | MP0000631_abnormal_neuroendocrine_gland | 1.47545015 |
| 30 | MP0003011_delayed_dark_adaptation | 1.46977906 |
| 31 | MP0001968_abnormal_touch/_nociception | 1.46793879 |
| 32 | MP0006036_abnormal_mitochondrial_physio | 1.45102879 |
| 33 | MP0008007_abnormal_cellular_replicative | 1.42933437 |
| 34 | MP0002638_abnormal_pupillary_reflex | 1.42739863 |
| 35 | MP0003786_premature_aging | 1.41775645 |
| 36 | MP0009046_muscle_twitch | 1.41236150 |
| 37 | MP0002160_abnormal_reproductive_system | 1.41207368 |
| 38 | MP0001485_abnormal_pinna_reflex | 1.37042184 |
| 39 | MP0000372_irregular_coat_pigmentation | 1.35518028 |
| 40 | MP0003186_abnormal_redox_activity | 1.34875116 |
| 41 | MP0008057_abnormal_DNA_replication | 1.34349718 |
| 42 | MP0005389_reproductive_system_phenotype | 1.32974288 |
| 43 | MP0005551_abnormal_eye_electrophysiolog | 1.32964847 |
| 44 | MP0002837_dystrophic_cardiac_calcinosis | 1.32838576 |
| 45 | MP0001919_abnormal_reproductive_system | 1.30809238 |
| 46 | MP0003123_paternal_imprinting | 1.30749717 |
| 47 | MP0000049_abnormal_middle_ear | 1.26582345 |
| 48 | MP0004142_abnormal_muscle_tone | 1.24957949 |
| 49 | MP0002653_abnormal_ependyma_morphology | 1.16946335 |
| 50 | MP0002210_abnormal_sex_determination | 1.16607993 |
| 51 | MP0001905_abnormal_dopamine_level | 1.16138140 |
| 52 | MP0004133_heterotaxia | 1.16108581 |
| 53 | MP0004147_increased_porphyrin_level | 1.10699128 |
| 54 | MP0005253_abnormal_eye_physiology | 1.10190485 |
| 55 | MP0003937_abnormal_limbs/digits/tail_de | 1.09951588 |
| 56 | MP0008995_early_reproductive_senescence | 1.09868664 |
| 57 | MP0003315_abnormal_perineum_morphology | 1.06843558 |
| 58 | MP0005671_abnormal_response_to | 1.06212538 |
| 59 | MP0006035_abnormal_mitochondrial_morpho | 1.04620730 |
| 60 | MP0002095_abnormal_skin_pigmentation | 1.03561459 |
| 61 | MP0001929_abnormal_gametogenesis | 1.02191787 |
| 62 | MP0003136_yellow_coat_color | 1.02144639 |
| 63 | MP0003567_abnormal_fetal_cardiomyocyte | 1.01866573 |
| 64 | MP0002234_abnormal_pharynx_morphology | 1.01670673 |
| 65 | MP0001286_abnormal_eye_development | 1.00522179 |
| 66 | MP0001188_hyperpigmentation | 0.98315491 |
| 67 | MP0006276_abnormal_autonomic_nervous | 0.96762111 |
| 68 | MP0003880_abnormal_central_pattern | 0.96470463 |
| 69 | MP0005379_endocrine/exocrine_gland_phen | 0.96249300 |
| 70 | MP0005195_abnormal_posterior_eye | 0.90922610 |
| 71 | MP0003938_abnormal_ear_development | 0.90875198 |
| 72 | MP0003122_maternal_imprinting | 0.90548931 |
| 73 | MP0009697_abnormal_copulation | 0.89444520 |
| 74 | MP0000653_abnormal_sex_gland | 0.89314167 |
| 75 | MP0001145_abnormal_male_reproductive | 0.89313630 |
| 76 | MP0005075_abnormal_melanosome_morpholog | 0.88077542 |
| 77 | MP0003890_abnormal_embryonic-extraembry | 0.87641137 |
| 78 | MP0004145_abnormal_muscle_electrophysio | 0.87463627 |
| 79 | MP0002233_abnormal_nose_morphology | 0.87023773 |
| 80 | MP0002272_abnormal_nervous_system | 0.86632164 |
| 81 | MP0001984_abnormal_olfaction | 0.86119972 |
| 82 | MP0002752_abnormal_somatic_nervous | 0.82491592 |
| 83 | MP0002277_abnormal_respiratory_mucosa | 0.82061331 |
| 84 | MP0009745_abnormal_behavioral_response | 0.81632140 |
| 85 | MP0008875_abnormal_xenobiotic_pharmacok | 0.81113142 |
| 86 | MP0000778_abnormal_nervous_system | 0.77810557 |
| 87 | MP0002876_abnormal_thyroid_physiology | 0.77362248 |
| 88 | MP0003698_abnormal_male_reproductive | 0.76571710 |
| 89 | MP0001119_abnormal_female_reproductive | 0.74740936 |
| 90 | MP0005391_vision/eye_phenotype | 0.74097302 |
| 91 | MP0003646_muscle_fatigue | 0.72619333 |
| 92 | MP0005410_abnormal_fertilization | 0.72201484 |
| 93 | MP0002184_abnormal_innervation | 0.71756608 |
| 94 | MP0002751_abnormal_autonomic_nervous | 0.70567585 |
| 95 | MP0010030_abnormal_orbit_morphology | 0.70188521 |
| 96 | MP0002557_abnormal_social/conspecific_i | 0.70159558 |
| 97 | MP0001764_abnormal_homeostasis | 0.69817205 |
| 98 | MP0001727_abnormal_embryo_implantation | 0.68907815 |
| 99 | MP0002735_abnormal_chemical_nociception | 0.67351417 |
| 100 | MP0002733_abnormal_thermal_nociception | 0.62559567 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.85246292 |
| 2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.40322262 |
| 3 | Acute encephalopathy (HP:0006846) | 4.21919932 |
| 4 | Progressive macrocephaly (HP:0004481) | 3.96729350 |
| 5 | Mitochondrial inheritance (HP:0001427) | 3.93960094 |
| 6 | Increased CSF lactate (HP:0002490) | 3.69763053 |
| 7 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.38295029 |
| 8 | Increased hepatocellular lipid droplets (HP:0006565) | 3.37008896 |
| 9 | Reticulocytopenia (HP:0001896) | 3.34389090 |
| 10 | Cerebral edema (HP:0002181) | 3.23197609 |
| 11 | Abnormality of midbrain morphology (HP:0002418) | 3.22920933 |
| 12 | Molar tooth sign on MRI (HP:0002419) | 3.22920933 |
| 13 | Lipid accumulation in hepatocytes (HP:0006561) | 3.16725584 |
| 14 | Macrocytic anemia (HP:0001972) | 3.14275088 |
| 15 | Hepatocellular necrosis (HP:0001404) | 3.12138969 |
| 16 | Abnormal number of erythroid precursors (HP:0012131) | 3.07695744 |
| 17 | 3-Methylglutaconic aciduria (HP:0003535) | 3.05511976 |
| 18 | Pancreatic cysts (HP:0001737) | 3.05012471 |
| 19 | Pancreatic fibrosis (HP:0100732) | 2.96895655 |
| 20 | Hepatic necrosis (HP:0002605) | 2.93574291 |
| 21 | Colon cancer (HP:0003003) | 2.86202143 |
| 22 | Renal Fanconi syndrome (HP:0001994) | 2.78741658 |
| 23 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.73360121 |
| 24 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.73360121 |
| 25 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.66625132 |
| 26 | Abnormality of the labia minora (HP:0012880) | 2.65520724 |
| 27 | Increased serum lactate (HP:0002151) | 2.62743081 |
| 28 | True hermaphroditism (HP:0010459) | 2.62542304 |
| 29 | Chromsome breakage (HP:0040012) | 2.62358680 |
| 30 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.59068912 |
| 31 | Nephronophthisis (HP:0000090) | 2.52007387 |
| 32 | Birth length less than 3rd percentile (HP:0003561) | 2.51827262 |
| 33 | Increased intramyocellular lipid droplets (HP:0012240) | 2.51009748 |
| 34 | Lactic acidosis (HP:0003128) | 2.47461763 |
| 35 | Meckel diverticulum (HP:0002245) | 2.46610572 |
| 36 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.44503345 |
| 37 | Optic disc pallor (HP:0000543) | 2.43052629 |
| 38 | Absent thumb (HP:0009777) | 2.42079413 |
| 39 | Leukodystrophy (HP:0002415) | 2.41752155 |
| 40 | Abnormality of the ileum (HP:0001549) | 2.41699843 |
| 41 | Medial flaring of the eyebrow (HP:0010747) | 2.39162375 |
| 42 | Abnormality of chromosome stability (HP:0003220) | 2.28988614 |
| 43 | Methylmalonic acidemia (HP:0002912) | 2.26821045 |
| 44 | Hyperglycinemia (HP:0002154) | 2.25715432 |
| 45 | Volvulus (HP:0002580) | 2.24435120 |
| 46 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.18969409 |
| 47 | Abnormality of alanine metabolism (HP:0010916) | 2.18969409 |
| 48 | Hyperalaninemia (HP:0003348) | 2.18969409 |
| 49 | Pallor (HP:0000980) | 2.18361168 |
| 50 | Congenital, generalized hypertrichosis (HP:0004540) | 2.18311183 |
| 51 | Pendular nystagmus (HP:0012043) | 2.16582710 |
| 52 | Congenital stationary night blindness (HP:0007642) | 2.15632981 |
| 53 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.14336816 |
| 54 | Sclerocornea (HP:0000647) | 2.14168053 |
| 55 | Abnormality of the preputium (HP:0100587) | 2.12575095 |
| 56 | Septo-optic dysplasia (HP:0100842) | 2.11625527 |
| 57 | Exertional dyspnea (HP:0002875) | 2.10619232 |
| 58 | Abnormality of renal resorption (HP:0011038) | 2.09289641 |
| 59 | Triphalangeal thumb (HP:0001199) | 2.08783893 |
| 60 | Lethargy (HP:0001254) | 2.08206770 |
| 61 | Exercise intolerance (HP:0003546) | 2.06999395 |
| 62 | Respiratory failure (HP:0002878) | 2.05751291 |
| 63 | Methylmalonic aciduria (HP:0012120) | 2.01762712 |
| 64 | Increased muscle lipid content (HP:0009058) | 2.00859756 |
| 65 | Anencephaly (HP:0002323) | 1.97837550 |
| 66 | Abnormality of the renal medulla (HP:0100957) | 1.95272141 |
| 67 | Rib fusion (HP:0000902) | 1.93476807 |
| 68 | Ectopic kidney (HP:0000086) | 1.92635753 |
| 69 | Gait imbalance (HP:0002141) | 1.92624764 |
| 70 | Renal cortical cysts (HP:0000803) | 1.92166642 |
| 71 | Patellar aplasia (HP:0006443) | 1.90454355 |
| 72 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.87681937 |
| 73 | Abnormality of the renal cortex (HP:0011035) | 1.84070533 |
| 74 | Abnormality of serum amino acid levels (HP:0003112) | 1.82685582 |
| 75 | Horseshoe kidney (HP:0000085) | 1.82559965 |
| 76 | Cleft eyelid (HP:0000625) | 1.82311392 |
| 77 | Pancytopenia (HP:0001876) | 1.79477757 |
| 78 | Congenital primary aphakia (HP:0007707) | 1.79385204 |
| 79 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.78520623 |
| 80 | Sloping forehead (HP:0000340) | 1.78122794 |
| 81 | Aplastic anemia (HP:0001915) | 1.75519808 |
| 82 | Hypoplasia of the pons (HP:0012110) | 1.74803489 |
| 83 | Cystic liver disease (HP:0006706) | 1.74418274 |
| 84 | Microretrognathia (HP:0000308) | 1.74373985 |
| 85 | Abnormality of urine glucose concentration (HP:0011016) | 1.73154658 |
| 86 | Glycosuria (HP:0003076) | 1.73154658 |
| 87 | Supernumerary spleens (HP:0009799) | 1.70177671 |
| 88 | Nephrogenic diabetes insipidus (HP:0009806) | 1.69879082 |
| 89 | Oligodactyly (hands) (HP:0001180) | 1.69828674 |
| 90 | Respiratory difficulties (HP:0002880) | 1.69133163 |
| 91 | Duodenal stenosis (HP:0100867) | 1.68990999 |
| 92 | Small intestinal stenosis (HP:0012848) | 1.68990999 |
| 93 | Adrenal hypoplasia (HP:0000835) | 1.68440323 |
| 94 | Abnormal number of incisors (HP:0011064) | 1.67553572 |
| 95 | Type I transferrin isoform profile (HP:0003642) | 1.67161499 |
| 96 | Abnormality of the pons (HP:0007361) | 1.65743747 |
| 97 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.65393789 |
| 98 | X-linked dominant inheritance (HP:0001423) | 1.65338013 |
| 99 | Postaxial foot polydactyly (HP:0001830) | 1.65125005 |
| 100 | IgG deficiency (HP:0004315) | 1.64492620 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CDC7 | 4.04776771 |
| 2 | TLK1 | 3.69395110 |
| 3 | ZAK | 3.43187848 |
| 4 | VRK2 | 3.11313630 |
| 5 | BUB1 | 2.82176187 |
| 6 | STK16 | 2.72350392 |
| 7 | VRK1 | 2.62059871 |
| 8 | NUAK1 | 2.55962833 |
| 9 | PLK4 | 2.16512076 |
| 10 | NEK1 | 2.04808259 |
| 11 | MAP4K2 | 2.01815941 |
| 12 | SRPK1 | 1.93391415 |
| 13 | BMPR1B | 1.90712790 |
| 14 | MKNK2 | 1.88778869 |
| 15 | PLK3 | 1.86075972 |
| 16 | BCKDK | 1.83846677 |
| 17 | MST4 | 1.83098219 |
| 18 | WEE1 | 1.65294781 |
| 19 | DYRK2 | 1.58585149 |
| 20 | MKNK1 | 1.57424044 |
| 21 | WNK3 | 1.56750093 |
| 22 | TTK | 1.51626703 |
| 23 | PLK1 | 1.48538005 |
| 24 | EIF2AK1 | 1.40879963 |
| 25 | WNK4 | 1.40097142 |
| 26 | MAP2K7 | 1.37152085 |
| 27 | TNIK | 1.32263130 |
| 28 | ADRBK2 | 1.31945863 |
| 29 | BRSK2 | 1.27797396 |
| 30 | CHEK2 | 1.24602956 |
| 31 | TAF1 | 1.22674595 |
| 32 | TRIM28 | 1.22021284 |
| 33 | CDK19 | 1.20784694 |
| 34 | GRK1 | 1.19535395 |
| 35 | AURKB | 1.19301406 |
| 36 | AURKA | 1.16723550 |
| 37 | NME1 | 1.08507202 |
| 38 | PNCK | 1.07530342 |
| 39 | MAP3K4 | 1.07316138 |
| 40 | ATR | 1.06564572 |
| 41 | EIF2AK3 | 1.06548494 |
| 42 | NEK2 | 1.05966242 |
| 43 | MAPK13 | 0.97136863 |
| 44 | FRK | 0.96220742 |
| 45 | OXSR1 | 0.95407159 |
| 46 | PLK2 | 0.95285647 |
| 47 | CCNB1 | 0.87436503 |
| 48 | STK39 | 0.83695425 |
| 49 | RPS6KA5 | 0.81691449 |
| 50 | PASK | 0.81304882 |
| 51 | CSNK1G3 | 0.80274277 |
| 52 | EIF2AK2 | 0.79183743 |
| 53 | TAOK3 | 0.74706064 |
| 54 | CSNK2A2 | 0.73449104 |
| 55 | TSSK6 | 0.73220109 |
| 56 | CSNK1G2 | 0.72757987 |
| 57 | CSNK1G1 | 0.72697324 |
| 58 | PBK | 0.69496782 |
| 59 | INSRR | 0.67867232 |
| 60 | PRKCG | 0.67339127 |
| 61 | CSNK2A1 | 0.67112805 |
| 62 | ATM | 0.66687040 |
| 63 | BRSK1 | 0.66271610 |
| 64 | PINK1 | 0.64997085 |
| 65 | CHEK1 | 0.64321379 |
| 66 | CDK8 | 0.63989762 |
| 67 | MAP3K12 | 0.60050136 |
| 68 | TEC | 0.59417645 |
| 69 | NME2 | 0.57875460 |
| 70 | MINK1 | 0.56787887 |
| 71 | CSNK1E | 0.56561242 |
| 72 | TXK | 0.56025604 |
| 73 | PRKCI | 0.55696964 |
| 74 | RPS6KA4 | 0.54777788 |
| 75 | PHKG2 | 0.54171497 |
| 76 | PHKG1 | 0.54171497 |
| 77 | RPS6KB2 | 0.51277589 |
| 78 | CDK3 | 0.51212608 |
| 79 | DAPK3 | 0.50009891 |
| 80 | KDR | 0.49722607 |
| 81 | CASK | 0.49131563 |
| 82 | DYRK3 | 0.48851470 |
| 83 | CSNK1A1L | 0.46532247 |
| 84 | TIE1 | 0.45727211 |
| 85 | CDK7 | 0.43666586 |
| 86 | LIMK1 | 0.43286567 |
| 87 | PIK3CA | 0.42823484 |
| 88 | PDK2 | 0.42412705 |
| 89 | BCR | 0.41379320 |
| 90 | PRKCQ | 0.41023116 |
| 91 | MAPKAPK5 | 0.40647984 |
| 92 | EPHB2 | 0.40587177 |
| 93 | CDK14 | 0.40062475 |
| 94 | ALK | 0.39622319 |
| 95 | ABL2 | 0.38771678 |
| 96 | ADRBK1 | 0.37770615 |
| 97 | TESK2 | 0.36734526 |
| 98 | CDK1 | 0.36447518 |
| 99 | PRKDC | 0.35394806 |
| 100 | STK4 | 0.35121287 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.30805116 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.59876080 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 3.42589654 |
| 4 | DNA replication_Homo sapiens_hsa03030 | 3.25597133 |
| 5 | Mismatch repair_Homo sapiens_hsa03430 | 3.24652036 |
| 6 | Parkinsons disease_Homo sapiens_hsa05012 | 3.14358052 |
| 7 | Homologous recombination_Homo sapiens_hsa03440 | 3.00007860 |
| 8 | Protein export_Homo sapiens_hsa03060 | 2.90468637 |
| 9 | RNA polymerase_Homo sapiens_hsa03020 | 2.81011598 |
| 10 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.39889386 |
| 11 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.24096965 |
| 12 | Spliceosome_Homo sapiens_hsa03040 | 2.22449477 |
| 13 | Huntingtons disease_Homo sapiens_hsa05016 | 2.21484261 |
| 14 | Base excision repair_Homo sapiens_hsa03410 | 2.14491618 |
| 15 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.07088799 |
| 16 | Alzheimers disease_Homo sapiens_hsa05010 | 1.97629446 |
| 17 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.94951977 |
| 18 | RNA degradation_Homo sapiens_hsa03018 | 1.90808811 |
| 19 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.83613802 |
| 20 | Basal transcription factors_Homo sapiens_hsa03022 | 1.77342424 |
| 21 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.76735781 |
| 22 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.73822312 |
| 23 | RNA transport_Homo sapiens_hsa03013 | 1.70197307 |
| 24 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.64799476 |
| 25 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.52908192 |
| 26 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.51814879 |
| 27 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.46957535 |
| 28 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.34719502 |
| 29 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.33184132 |
| 30 | Purine metabolism_Homo sapiens_hsa00230 | 1.24709954 |
| 31 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.14880867 |
| 32 | Cell cycle_Homo sapiens_hsa04110 | 1.14143688 |
| 33 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.13043922 |
| 34 | Sulfur relay system_Homo sapiens_hsa04122 | 1.12515013 |
| 35 | Phototransduction_Homo sapiens_hsa04744 | 1.10925795 |
| 36 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.09723448 |
| 37 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.08930985 |
| 38 | Asthma_Homo sapiens_hsa05310 | 1.00573767 |
| 39 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.98529579 |
| 40 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.95459441 |
| 41 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.95367625 |
| 42 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.95177830 |
| 43 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.92124353 |
| 44 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.88751425 |
| 45 | Alcoholism_Homo sapiens_hsa05034 | 0.88249726 |
| 46 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.87960850 |
| 47 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.85417236 |
| 48 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.77911303 |
| 49 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.73505948 |
| 50 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.70264993 |
| 51 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.69516833 |
| 52 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.68795901 |
| 53 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.66638331 |
| 54 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.66249024 |
| 55 | Allograft rejection_Homo sapiens_hsa05330 | 0.64815970 |
| 56 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.64172695 |
| 57 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.63940062 |
| 58 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.63432076 |
| 59 | Metabolic pathways_Homo sapiens_hsa01100 | 0.63363534 |
| 60 | Peroxisome_Homo sapiens_hsa04146 | 0.62271163 |
| 61 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.61199645 |
| 62 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.60468584 |
| 63 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.58429392 |
| 64 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.55583964 |
| 65 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.53939495 |
| 66 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.52851471 |
| 67 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.52348442 |
| 68 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.51666798 |
| 69 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.51499850 |
| 70 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.49981366 |
| 71 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.47915483 |
| 72 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.47393799 |
| 73 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.46168475 |
| 74 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.45483529 |
| 75 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.44611085 |
| 76 | Nicotine addiction_Homo sapiens_hsa05033 | 0.43665771 |
| 77 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.42141756 |
| 78 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.40737382 |
| 79 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.40012503 |
| 80 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.39997347 |
| 81 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.39730625 |
| 82 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.37838553 |
| 83 | Retinol metabolism_Homo sapiens_hsa00830 | 0.37461233 |
| 84 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.36522073 |
| 85 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.32846711 |
| 86 | Olfactory transduction_Homo sapiens_hsa04740 | 0.32148829 |
| 87 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.29713530 |
| 88 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.25861975 |
| 89 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.22866665 |
| 90 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.22714080 |
| 91 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.22321253 |
| 92 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.20839556 |
| 93 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.19506581 |
| 94 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.18079405 |
| 95 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.17994632 |
| 96 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.17047172 |
| 97 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.16368720 |
| 98 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.15976250 |
| 99 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.13678320 |
| 100 | Carbon metabolism_Homo sapiens_hsa01200 | 0.12707591 |

