

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.90723074 |
| 2 | ATP synthesis coupled proton transport (GO:0015986) | 5.90723074 |
| 3 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.51624699 |
| 4 | protein neddylation (GO:0045116) | 4.50843442 |
| 5 | chaperone-mediated protein transport (GO:0072321) | 4.49357477 |
| 6 | DNA deamination (GO:0045006) | 4.41899048 |
| 7 | behavioral response to nicotine (GO:0035095) | 4.33280288 |
| 8 | regulation of hypersensitivity (GO:0002883) | 4.15701025 |
| 9 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 4.14754797 |
| 10 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.13953810 |
| 11 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 4.11076209 |
| 12 | NADH dehydrogenase complex assembly (GO:0010257) | 3.92805288 |
| 13 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.92805288 |
| 14 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.92805288 |
| 15 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.86758529 |
| 16 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.82223219 |
| 17 | protein complex biogenesis (GO:0070271) | 3.79866779 |
| 18 | respiratory electron transport chain (GO:0022904) | 3.74211131 |
| 19 | electron transport chain (GO:0022900) | 3.71726182 |
| 20 | chromatin remodeling at centromere (GO:0031055) | 3.71430849 |
| 21 | piRNA metabolic process (GO:0034587) | 3.59723854 |
| 22 | CENP-A containing nucleosome assembly (GO:0034080) | 3.58527053 |
| 23 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 3.51635975 |
| 24 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.46399003 |
| 25 | retinal cone cell development (GO:0046549) | 3.45859848 |
| 26 | histone exchange (GO:0043486) | 3.44856586 |
| 27 | base-excision repair, AP site formation (GO:0006285) | 3.44845645 |
| 28 | DNA double-strand break processing (GO:0000729) | 3.43924712 |
| 29 | termination of RNA polymerase III transcription (GO:0006386) | 3.41424680 |
| 30 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.41424680 |
| 31 | maturation of 5.8S rRNA (GO:0000460) | 3.40841391 |
| 32 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.37105290 |
| 33 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.31443643 |
| 34 | rRNA modification (GO:0000154) | 3.31255945 |
| 35 | maturation of SSU-rRNA (GO:0030490) | 3.29680527 |
| 36 | ATP biosynthetic process (GO:0006754) | 3.29207503 |
| 37 | organelle disassembly (GO:1903008) | 3.25436571 |
| 38 | regulation of acute inflammatory response to antigenic stimulus (GO:0002864) | 3.24210702 |
| 39 | nucleotide transmembrane transport (GO:1901679) | 3.22415869 |
| 40 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.22318137 |
| 41 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 3.19338150 |
| 42 | DNA damage response, detection of DNA damage (GO:0042769) | 3.16831637 |
| 43 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.16766497 |
| 44 | protein polyglutamylation (GO:0018095) | 3.15721923 |
| 45 | fucose catabolic process (GO:0019317) | 3.13228889 |
| 46 | L-fucose metabolic process (GO:0042354) | 3.13228889 |
| 47 | L-fucose catabolic process (GO:0042355) | 3.13228889 |
| 48 | DNA replication checkpoint (GO:0000076) | 3.03819849 |
| 49 | ribosomal large subunit biogenesis (GO:0042273) | 3.02975394 |
| 50 | GPI anchor biosynthetic process (GO:0006506) | 2.94886437 |
| 51 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.93787330 |
| 52 | resolution of meiotic recombination intermediates (GO:0000712) | 2.93541451 |
| 53 | rRNA methylation (GO:0031167) | 2.92465477 |
| 54 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.92321213 |
| 55 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.92321213 |
| 56 | axoneme assembly (GO:0035082) | 2.92088068 |
| 57 | kynurenine metabolic process (GO:0070189) | 2.92012357 |
| 58 | DNA methylation involved in gamete generation (GO:0043046) | 2.89586621 |
| 59 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.89134084 |
| 60 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.88036982 |
| 61 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.88036982 |
| 62 | platelet dense granule organization (GO:0060155) | 2.86073049 |
| 63 | regulation of rhodopsin mediated signaling pathway (GO:0022400) | 2.85101979 |
| 64 | GPI anchor metabolic process (GO:0006505) | 2.83450543 |
| 65 | rRNA catabolic process (GO:0016075) | 2.82205510 |
| 66 | ribonucleoprotein complex disassembly (GO:0032988) | 2.82030344 |
| 67 | cellular component biogenesis (GO:0044085) | 2.80264097 |
| 68 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.79698944 |
| 69 | respiratory chain complex IV assembly (GO:0008535) | 2.77008791 |
| 70 | kinetochore assembly (GO:0051382) | 2.74087736 |
| 71 | recombinational repair (GO:0000725) | 2.71634275 |
| 72 | double-strand break repair via homologous recombination (GO:0000724) | 2.71497658 |
| 73 | proton transport (GO:0015992) | 2.70540639 |
| 74 | indole-containing compound catabolic process (GO:0042436) | 2.69889940 |
| 75 | indolalkylamine catabolic process (GO:0046218) | 2.69889940 |
| 76 | tryptophan catabolic process (GO:0006569) | 2.69889940 |
| 77 | rRNA metabolic process (GO:0016072) | 2.68960690 |
| 78 | rhodopsin mediated signaling pathway (GO:0016056) | 2.68243820 |
| 79 | rRNA processing (GO:0006364) | 2.67630706 |
| 80 | hydrogen transport (GO:0006818) | 2.65037008 |
| 81 | intra-S DNA damage checkpoint (GO:0031573) | 2.64673814 |
| 82 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.63956046 |
| 83 | DNA replication-independent nucleosome organization (GO:0034724) | 2.63956046 |
| 84 | regulation of mesoderm development (GO:2000380) | 2.61169741 |
| 85 | aldehyde catabolic process (GO:0046185) | 2.60274679 |
| 86 | mitochondrion morphogenesis (GO:0070584) | 2.59765782 |
| 87 | hydrogen ion transmembrane transport (GO:1902600) | 2.59376427 |
| 88 | synapsis (GO:0007129) | 2.57790165 |
| 89 | ribosomal small subunit assembly (GO:0000028) | 2.56766860 |
| 90 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.56633584 |
| 91 | ubiquinone biosynthetic process (GO:0006744) | 2.55009779 |
| 92 | pseudouridine synthesis (GO:0001522) | 2.54903961 |
| 93 | kinetochore organization (GO:0051383) | 2.54717873 |
| 94 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.53093697 |
| 95 | viral transcription (GO:0019083) | 2.53033570 |
| 96 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.52768552 |
| 97 | protein-cofactor linkage (GO:0018065) | 2.52519999 |
| 98 | ubiquinone metabolic process (GO:0006743) | 2.50285957 |
| 99 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.49241964 |
| 100 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.49233173 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.36843611 |
| 2 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.24119378 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.06724482 |
| 4 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.28437153 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.07694793 |
| 6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.97837725 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.97257705 |
| 8 | VDR_22108803_ChIP-Seq_LS180_Human | 2.84109771 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.79431783 |
| 10 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.72203516 |
| 11 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.54087850 |
| 12 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.46526273 |
| 13 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.27245899 |
| 14 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.24091562 |
| 15 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.22718470 |
| 16 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.19697588 |
| 17 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.19199861 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.11874206 |
| 19 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.09578043 |
| 20 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.91817310 |
| 21 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.80662680 |
| 22 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.72351147 |
| 23 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.69771974 |
| 24 | EWS_26573619_Chip-Seq_HEK293_Human | 1.69126947 |
| 25 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.68716852 |
| 26 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.65126983 |
| 27 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.64938923 |
| 28 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.60057727 |
| 29 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.54150539 |
| 30 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.52514914 |
| 31 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.52423639 |
| 32 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.51452608 |
| 33 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.51448965 |
| 34 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.49463869 |
| 35 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.46361454 |
| 36 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.42994100 |
| 37 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.42644961 |
| 38 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.41094166 |
| 39 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.40274722 |
| 40 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.37526626 |
| 41 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.37526626 |
| 42 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.35076099 |
| 43 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.31194474 |
| 44 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.30413870 |
| 45 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.30221541 |
| 46 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.29262808 |
| 47 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.28965365 |
| 48 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.26681458 |
| 49 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.26573534 |
| 50 | AR_20517297_ChIP-Seq_VCAP_Human | 1.26213670 |
| 51 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.24641272 |
| 52 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.24225974 |
| 53 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.24126593 |
| 54 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.20847251 |
| 55 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.19840421 |
| 56 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.19686164 |
| 57 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.17545070 |
| 58 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.16777114 |
| 59 | NCOR_22424771_ChIP-Seq_293T_Human | 1.15714886 |
| 60 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.15092530 |
| 61 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.14779427 |
| 62 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.14514876 |
| 63 | FUS_26573619_Chip-Seq_HEK293_Human | 1.14124016 |
| 64 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.12263535 |
| 65 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.11694863 |
| 66 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.11588969 |
| 67 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.10758653 |
| 68 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.10419778 |
| 69 | GATA3_26560356_Chip-Seq_TH2_Human | 1.10356957 |
| 70 | P300_19829295_ChIP-Seq_ESCs_Human | 1.10055091 |
| 71 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.09398754 |
| 72 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.09306606 |
| 73 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.09002158 |
| 74 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.09002158 |
| 75 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.08597023 |
| 76 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.06480017 |
| 77 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.04980011 |
| 78 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.04433091 |
| 79 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.02873957 |
| 80 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.02416865 |
| 81 | ERA_21632823_ChIP-Seq_H3396_Human | 1.02374203 |
| 82 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.99980941 |
| 83 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.98379264 |
| 84 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.98269116 |
| 85 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.98027286 |
| 86 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.96327736 |
| 87 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.92806133 |
| 88 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.92729237 |
| 89 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.91698353 |
| 90 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.90950085 |
| 91 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.89488260 |
| 92 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.88120350 |
| 93 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.87531696 |
| 94 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.87444086 |
| 95 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.87325837 |
| 96 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.87157297 |
| 97 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.86406022 |
| 98 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.85392031 |
| 99 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.85392031 |
| 100 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.84663594 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 3.15417178 |
| 2 | MP0002163_abnormal_gland_morphology | 3.14926290 |
| 3 | MP0003787_abnormal_imprinting | 3.06389536 |
| 4 | MP0008877_abnormal_DNA_methylation | 2.88017474 |
| 5 | MP0005646_abnormal_pituitary_gland | 2.58120852 |
| 6 | MP0008872_abnormal_physiological_respon | 2.51949456 |
| 7 | MP0005645_abnormal_hypothalamus_physiol | 2.50987848 |
| 8 | MP0004147_increased_porphyrin_level | 2.25168470 |
| 9 | MP0002102_abnormal_ear_morphology | 2.10532878 |
| 10 | MP0003195_calcinosis | 2.00994538 |
| 11 | MP0005075_abnormal_melanosome_morpholog | 1.98493983 |
| 12 | MP0003786_premature_aging | 1.95163428 |
| 13 | MP0003646_muscle_fatigue | 1.93426494 |
| 14 | MP0008875_abnormal_xenobiotic_pharmacok | 1.91705140 |
| 15 | MP0001986_abnormal_taste_sensitivity | 1.79740035 |
| 16 | MP0003806_abnormal_nucleotide_metabolis | 1.79519183 |
| 17 | MP0005551_abnormal_eye_electrophysiolog | 1.79349954 |
| 18 | MP0005379_endocrine/exocrine_gland_phen | 1.79280277 |
| 19 | MP0002837_dystrophic_cardiac_calcinosis | 1.71023953 |
| 20 | MP0005377_hearing/vestibular/ear_phenot | 1.68584086 |
| 21 | MP0003878_abnormal_ear_physiology | 1.68584086 |
| 22 | MP0001502_abnormal_circadian_rhythm | 1.62357961 |
| 23 | MP0002876_abnormal_thyroid_physiology | 1.60853022 |
| 24 | MP0003718_maternal_effect | 1.60580596 |
| 25 | MP0008058_abnormal_DNA_repair | 1.59206201 |
| 26 | MP0004142_abnormal_muscle_tone | 1.56924760 |
| 27 | MP0006035_abnormal_mitochondrial_morpho | 1.56364395 |
| 28 | MP0005671_abnormal_response_to | 1.55046491 |
| 29 | MP0003183_abnormal_peptide_metabolism | 1.54933857 |
| 30 | MP0001968_abnormal_touch/_nociception | 1.53681514 |
| 31 | MP0001293_anophthalmia | 1.51739214 |
| 32 | MP0005389_reproductive_system_phenotype | 1.50368215 |
| 33 | MP0002148_abnormal_hypersensitivity_rea | 1.45466140 |
| 34 | MP0002736_abnormal_nociception_after | 1.44972984 |
| 35 | MP0001485_abnormal_pinna_reflex | 1.44892956 |
| 36 | MP0006036_abnormal_mitochondrial_physio | 1.42541513 |
| 37 | MP0010094_abnormal_chromosome_stability | 1.42322199 |
| 38 | MP0003136_yellow_coat_color | 1.41243222 |
| 39 | MP0002638_abnormal_pupillary_reflex | 1.35545858 |
| 40 | MP0004885_abnormal_endolymph | 1.35533581 |
| 41 | MP0001919_abnormal_reproductive_system | 1.31159906 |
| 42 | MP0000372_irregular_coat_pigmentation | 1.24999902 |
| 43 | MP0001440_abnormal_grooming_behavior | 1.24843998 |
| 44 | MP0009764_decreased_sensitivity_to | 1.24146624 |
| 45 | MP0002277_abnormal_respiratory_mucosa | 1.20944448 |
| 46 | MP0003693_abnormal_embryo_hatching | 1.20121743 |
| 47 | MP0009046_muscle_twitch | 1.20001280 |
| 48 | MP0001501_abnormal_sleep_pattern | 1.18511839 |
| 49 | MP0002272_abnormal_nervous_system | 1.18325914 |
| 50 | MP0003121_genomic_imprinting | 1.16790411 |
| 51 | MP0008789_abnormal_olfactory_epithelium | 1.16317599 |
| 52 | MP0002160_abnormal_reproductive_system | 1.16020689 |
| 53 | MP0003011_delayed_dark_adaptation | 1.15200386 |
| 54 | MP0001790_abnormal_immune_system | 1.14283109 |
| 55 | MP0005387_immune_system_phenotype | 1.14283109 |
| 56 | MP0000685_abnormal_immune_system | 1.13461209 |
| 57 | MP0003122_maternal_imprinting | 1.12961429 |
| 58 | MP0001835_abnormal_antigen_presentation | 1.12831787 |
| 59 | MP0001984_abnormal_olfaction | 1.12558546 |
| 60 | MP0001800_abnormal_humoral_immune | 1.12305254 |
| 61 | MP0000427_abnormal_hair_cycle | 1.08867676 |
| 62 | MP0009745_abnormal_behavioral_response | 1.08845810 |
| 63 | MP0001486_abnormal_startle_reflex | 1.05854276 |
| 64 | MP0006072_abnormal_retinal_apoptosis | 1.05563280 |
| 65 | MP0003567_abnormal_fetal_cardiomyocyte | 1.01488571 |
| 66 | MP0005670_abnormal_white_adipose | 1.01205049 |
| 67 | MP0005499_abnormal_olfactory_system | 1.00005572 |
| 68 | MP0005394_taste/olfaction_phenotype | 1.00005572 |
| 69 | MP0005332_abnormal_amino_acid | 0.98572060 |
| 70 | MP0001542_abnormal_bone_strength | 0.97744841 |
| 71 | MP0005360_urolithiasis | 0.95335972 |
| 72 | MP0008775_abnormal_heart_ventricle | 0.95079513 |
| 73 | MP0002733_abnormal_thermal_nociception | 0.92394454 |
| 74 | MP0002938_white_spotting | 0.90836856 |
| 75 | MP0006276_abnormal_autonomic_nervous | 0.90516951 |
| 76 | MP0004145_abnormal_muscle_electrophysio | 0.90495153 |
| 77 | MP0005167_abnormal_blood-brain_barrier | 0.90073770 |
| 78 | MP0002095_abnormal_skin_pigmentation | 0.87836236 |
| 79 | MP0001929_abnormal_gametogenesis | 0.87542770 |
| 80 | MP0004381_abnormal_hair_follicle | 0.86130992 |
| 81 | MP0005195_abnormal_posterior_eye | 0.85901136 |
| 82 | MP0001970_abnormal_pain_threshold | 0.83260365 |
| 83 | MP0004957_abnormal_blastocyst_morpholog | 0.83244041 |
| 84 | MP0001663_abnormal_digestive_system | 0.82764741 |
| 85 | MP0004742_abnormal_vestibular_system | 0.82707317 |
| 86 | MP0000631_abnormal_neuroendocrine_gland | 0.82609602 |
| 87 | MP0005253_abnormal_eye_physiology | 0.82207651 |
| 88 | MP0002006_tumorigenesis | 0.78840315 |
| 89 | MP0002572_abnormal_emotion/affect_behav | 0.78529577 |
| 90 | MP0004215_abnormal_myocardial_fiber | 0.77926455 |
| 91 | MP0001905_abnormal_dopamine_level | 0.76403792 |
| 92 | MP0003724_increased_susceptibility_to | 0.75905702 |
| 93 | MP0002210_abnormal_sex_determination | 0.75627796 |
| 94 | MP0002723_abnormal_immune_serum | 0.74479670 |
| 95 | MP0002234_abnormal_pharynx_morphology | 0.73450794 |
| 96 | MP0005410_abnormal_fertilization | 0.72434112 |
| 97 | MP0009785_altered_susceptibility_to | 0.71549369 |
| 98 | MP0002735_abnormal_chemical_nociception | 0.70952069 |
| 99 | MP0003698_abnormal_male_reproductive | 0.70596896 |
| 100 | MP0000653_abnormal_sex_gland | 0.70331741 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.66152603 |
| 2 | Acute encephalopathy (HP:0006846) | 4.23599397 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.16709927 |
| 4 | Congenital stationary night blindness (HP:0007642) | 4.14447982 |
| 5 | Mitochondrial inheritance (HP:0001427) | 3.92686696 |
| 6 | Progressive macrocephaly (HP:0004481) | 3.84059818 |
| 7 | Increased CSF lactate (HP:0002490) | 3.80269756 |
| 8 | Abnormality of midbrain morphology (HP:0002418) | 3.33801314 |
| 9 | Molar tooth sign on MRI (HP:0002419) | 3.33801314 |
| 10 | Hepatocellular necrosis (HP:0001404) | 3.16025752 |
| 11 | Lipid accumulation in hepatocytes (HP:0006561) | 3.15193933 |
| 12 | Pancreatic cysts (HP:0001737) | 3.09015347 |
| 13 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 3.04998802 |
| 14 | Oligodactyly (hands) (HP:0001180) | 3.01618108 |
| 15 | Increased hepatocellular lipid droplets (HP:0006565) | 2.99617156 |
| 16 | Pancreatic fibrosis (HP:0100732) | 2.95577825 |
| 17 | Cerebral edema (HP:0002181) | 2.94135041 |
| 18 | Septo-optic dysplasia (HP:0100842) | 2.92820834 |
| 19 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.90933306 |
| 20 | True hermaphroditism (HP:0010459) | 2.84448498 |
| 21 | Absent thumb (HP:0009777) | 2.80693859 |
| 22 | Sclerocornea (HP:0000647) | 2.74382315 |
| 23 | Anencephaly (HP:0002323) | 2.73301992 |
| 24 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.71357968 |
| 25 | Optic disc pallor (HP:0000543) | 2.70767542 |
| 26 | Asplenia (HP:0001746) | 2.68606522 |
| 27 | Hepatic necrosis (HP:0002605) | 2.67388639 |
| 28 | Reticulocytopenia (HP:0001896) | 2.63756549 |
| 29 | Abnormality of alanine metabolism (HP:0010916) | 2.60252773 |
| 30 | Hyperalaninemia (HP:0003348) | 2.60252773 |
| 31 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.60252773 |
| 32 | Nephronophthisis (HP:0000090) | 2.59566913 |
| 33 | Increased serum lactate (HP:0002151) | 2.58369783 |
| 34 | Congenital, generalized hypertrichosis (HP:0004540) | 2.56518937 |
| 35 | IgG deficiency (HP:0004315) | 2.51974481 |
| 36 | Attenuation of retinal blood vessels (HP:0007843) | 2.45523782 |
| 37 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.43987254 |
| 38 | Renal Fanconi syndrome (HP:0001994) | 2.41418070 |
| 39 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.40202503 |
| 40 | Type II lissencephaly (HP:0007260) | 2.35348736 |
| 41 | Supernumerary spleens (HP:0009799) | 2.29468010 |
| 42 | Lethargy (HP:0001254) | 2.27898684 |
| 43 | Papilledema (HP:0001085) | 2.27250377 |
| 44 | Lactic acidosis (HP:0003128) | 2.26701633 |
| 45 | Abnormality of the renal cortex (HP:0011035) | 2.26517587 |
| 46 | Horseshoe kidney (HP:0000085) | 2.20347885 |
| 47 | Exertional dyspnea (HP:0002875) | 2.19849408 |
| 48 | Ectopic kidney (HP:0000086) | 2.19078922 |
| 49 | Leukodystrophy (HP:0002415) | 2.16819887 |
| 50 | Pendular nystagmus (HP:0012043) | 2.15794252 |
| 51 | Abnormality of the renal medulla (HP:0100957) | 2.12270370 |
| 52 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.11603749 |
| 53 | Anophthalmia (HP:0000528) | 2.08818944 |
| 54 | Methylmalonic acidemia (HP:0002912) | 2.08515361 |
| 55 | Increased intramyocellular lipid droplets (HP:0012240) | 2.05577443 |
| 56 | Respiratory failure (HP:0002878) | 2.04618433 |
| 57 | Abnormal biliary tract physiology (HP:0012439) | 2.03963490 |
| 58 | Bile duct proliferation (HP:0001408) | 2.03963490 |
| 59 | Abolished electroretinogram (ERG) (HP:0000550) | 2.02398155 |
| 60 | Oligodactyly (HP:0012165) | 2.02383241 |
| 61 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.02321608 |
| 62 | Tetany (HP:0001281) | 2.01927398 |
| 63 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.00979902 |
| 64 | Abnormality of the labia minora (HP:0012880) | 2.00521136 |
| 65 | Hypomagnesemia (HP:0002917) | 1.97933053 |
| 66 | Hypothermia (HP:0002045) | 1.97833732 |
| 67 | Methylmalonic aciduria (HP:0012120) | 1.96162974 |
| 68 | Meckel diverticulum (HP:0002245) | 1.95185942 |
| 69 | Hypoproteinemia (HP:0003075) | 1.94813823 |
| 70 | Cystic liver disease (HP:0006706) | 1.90723355 |
| 71 | Brittle hair (HP:0002299) | 1.90522020 |
| 72 | Abnormality of the renal collecting system (HP:0004742) | 1.89751929 |
| 73 | Abnormality of DNA repair (HP:0003254) | 1.88158014 |
| 74 | Medial flaring of the eyebrow (HP:0010747) | 1.88121571 |
| 75 | Polydipsia (HP:0001959) | 1.86904816 |
| 76 | Abnormal drinking behavior (HP:0030082) | 1.86904816 |
| 77 | Stenosis of the external auditory canal (HP:0000402) | 1.86775326 |
| 78 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 1.86529292 |
| 79 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.86498022 |
| 80 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.86155047 |
| 81 | Abnormality of the ileum (HP:0001549) | 1.85999304 |
| 82 | Constricted visual fields (HP:0001133) | 1.84626033 |
| 83 | Lissencephaly (HP:0001339) | 1.84517375 |
| 84 | Optic nerve hypoplasia (HP:0000609) | 1.84220461 |
| 85 | Hypoplasia of the pons (HP:0012110) | 1.84184267 |
| 86 | Duplicated collecting system (HP:0000081) | 1.83997521 |
| 87 | Absent septum pellucidum (HP:0001331) | 1.83263638 |
| 88 | Increased muscle lipid content (HP:0009058) | 1.82662342 |
| 89 | Abnormality of the pons (HP:0007361) | 1.80878899 |
| 90 | Adactyly (HP:0009776) | 1.80264605 |
| 91 | Small hand (HP:0200055) | 1.80171159 |
| 92 | Abnormality of renal resorption (HP:0011038) | 1.80134791 |
| 93 | Abnormal number of erythroid precursors (HP:0012131) | 1.79825309 |
| 94 | Tubular atrophy (HP:0000092) | 1.79175219 |
| 95 | Polyuria (HP:0000103) | 1.79129238 |
| 96 | Type I transferrin isoform profile (HP:0003642) | 1.78879481 |
| 97 | X-linked dominant inheritance (HP:0001423) | 1.78451020 |
| 98 | Renal cortical cysts (HP:0000803) | 1.77634578 |
| 99 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.76082897 |
| 100 | Genetic anticipation (HP:0003743) | 1.75090023 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NUAK1 | 4.12642090 |
| 2 | TLK1 | 3.25629788 |
| 3 | ZAK | 3.12929461 |
| 4 | STK16 | 2.88602451 |
| 5 | TIE1 | 2.79968024 |
| 6 | GRK1 | 2.70945579 |
| 7 | TXK | 2.39685417 |
| 8 | FRK | 2.32604886 |
| 9 | TAOK3 | 2.20853835 |
| 10 | ACVR1B | 2.11023003 |
| 11 | VRK2 | 2.00364368 |
| 12 | ADRBK2 | 1.99512333 |
| 13 | BUB1 | 1.95675801 |
| 14 | EIF2AK3 | 1.92482603 |
| 15 | MAP4K2 | 1.82868040 |
| 16 | MKNK1 | 1.73255372 |
| 17 | TEC | 1.66811768 |
| 18 | MAPK13 | 1.66310303 |
| 19 | NEK1 | 1.64683183 |
| 20 | WNK4 | 1.63730043 |
| 21 | MAPKAPK3 | 1.61702059 |
| 22 | PLK3 | 1.60067188 |
| 23 | MAP4K1 | 1.58564284 |
| 24 | MKNK2 | 1.56955049 |
| 25 | STK39 | 1.54744141 |
| 26 | TRIM28 | 1.47739466 |
| 27 | PHKG1 | 1.46733546 |
| 28 | PHKG2 | 1.46733546 |
| 29 | NME1 | 1.41934927 |
| 30 | OXSR1 | 1.38100527 |
| 31 | EIF2AK2 | 1.34262751 |
| 32 | MAPKAPK5 | 1.30205536 |
| 33 | BMPR1B | 1.28357172 |
| 34 | EIF2AK1 | 1.21807005 |
| 35 | TSSK6 | 1.21797018 |
| 36 | CSNK1G2 | 1.19125383 |
| 37 | MAP2K6 | 1.18151410 |
| 38 | VRK1 | 1.13356215 |
| 39 | PLK4 | 1.12208703 |
| 40 | DYRK2 | 1.08301254 |
| 41 | PLK2 | 1.06628351 |
| 42 | PLK1 | 1.02086220 |
| 43 | WNK3 | 1.00834021 |
| 44 | PRKCI | 0.93800587 |
| 45 | PRKCG | 0.91764753 |
| 46 | IKBKB | 0.90345666 |
| 47 | PRKCQ | 0.88382050 |
| 48 | MUSK | 0.84319944 |
| 49 | SRPK1 | 0.83728659 |
| 50 | MAP2K7 | 0.82700375 |
| 51 | NEK2 | 0.82644803 |
| 52 | PIK3CG | 0.79686004 |
| 53 | AURKA | 0.78977596 |
| 54 | MST4 | 0.76841551 |
| 55 | RPS6KA5 | 0.72801841 |
| 56 | TNK2 | 0.70960051 |
| 57 | ADRBK1 | 0.70486647 |
| 58 | AURKB | 0.69330964 |
| 59 | NTRK2 | 0.67817938 |
| 60 | SYK | 0.67481189 |
| 61 | PINK1 | 0.67035240 |
| 62 | INSRR | 0.63585914 |
| 63 | DAPK2 | 0.62406689 |
| 64 | MINK1 | 0.61573999 |
| 65 | ITK | 0.60719839 |
| 66 | PIK3CA | 0.60292802 |
| 67 | TGFBR1 | 0.58867780 |
| 68 | TNIK | 0.58571051 |
| 69 | BCKDK | 0.57728876 |
| 70 | KIT | 0.57556539 |
| 71 | CSNK1G3 | 0.56439339 |
| 72 | CDC7 | 0.56415090 |
| 73 | TAF1 | 0.54233229 |
| 74 | DAPK1 | 0.54193420 |
| 75 | FES | 0.51164628 |
| 76 | CSNK1G1 | 0.49209535 |
| 77 | MYLK | 0.48541655 |
| 78 | CSNK2A2 | 0.47520015 |
| 79 | MARK3 | 0.46703170 |
| 80 | MAP3K4 | 0.45764120 |
| 81 | BMPR2 | 0.45113787 |
| 82 | STK3 | 0.44037608 |
| 83 | CSNK2A1 | 0.42278726 |
| 84 | PRKACA | 0.41697889 |
| 85 | MARK1 | 0.41385566 |
| 86 | PRKCA | 0.41208054 |
| 87 | PRKCE | 0.39224137 |
| 88 | ERBB3 | 0.38933377 |
| 89 | LYN | 0.37506483 |
| 90 | ABL2 | 0.36605670 |
| 91 | PDK2 | 0.36159373 |
| 92 | CHEK2 | 0.35292474 |
| 93 | PRKCD | 0.34523990 |
| 94 | PRKG1 | 0.34113705 |
| 95 | CSNK1A1 | 0.33326498 |
| 96 | DAPK3 | 0.33140296 |
| 97 | DMPK | 0.32979344 |
| 98 | WEE1 | 0.32843014 |
| 99 | CSNK1A1L | 0.31240649 |
| 100 | ALK | 0.30585323 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.67932545 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.54944169 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.15333165 |
| 4 | Ribosome_Homo sapiens_hsa03010 | 2.99637487 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 2.55026514 |
| 6 | Homologous recombination_Homo sapiens_hsa03440 | 2.42455122 |
| 7 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.36810970 |
| 8 | Asthma_Homo sapiens_hsa05310 | 2.19914970 |
| 9 | Huntingtons disease_Homo sapiens_hsa05016 | 2.14887356 |
| 10 | Phototransduction_Homo sapiens_hsa04744 | 2.12607672 |
| 11 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.02548759 |
| 12 | Alzheimers disease_Homo sapiens_hsa05010 | 1.98498996 |
| 13 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.92997536 |
| 14 | RNA degradation_Homo sapiens_hsa03018 | 1.92477141 |
| 15 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.83291692 |
| 16 | Protein export_Homo sapiens_hsa03060 | 1.82337042 |
| 17 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.82130637 |
| 18 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.80411334 |
| 19 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.78152589 |
| 20 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.72528745 |
| 21 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.70813229 |
| 22 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.67615521 |
| 23 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.67116531 |
| 24 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.61973591 |
| 25 | Basal transcription factors_Homo sapiens_hsa03022 | 1.61103784 |
| 26 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.59593216 |
| 27 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.55320944 |
| 28 | Mismatch repair_Homo sapiens_hsa03430 | 1.47008095 |
| 29 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.45278630 |
| 30 | Sulfur relay system_Homo sapiens_hsa04122 | 1.44278029 |
| 31 | Base excision repair_Homo sapiens_hsa03410 | 1.42295512 |
| 32 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.41374174 |
| 33 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.39926711 |
| 34 | Spliceosome_Homo sapiens_hsa03040 | 1.29913495 |
| 35 | Allograft rejection_Homo sapiens_hsa05330 | 1.23490312 |
| 36 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.21777944 |
| 37 | DNA replication_Homo sapiens_hsa03030 | 1.21133616 |
| 38 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.16211940 |
| 39 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.12472792 |
| 40 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.11560491 |
| 41 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.10674400 |
| 42 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.09860666 |
| 43 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.09073033 |
| 44 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.08822146 |
| 45 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.07988018 |
| 46 | Peroxisome_Homo sapiens_hsa04146 | 1.03893225 |
| 47 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.01836351 |
| 48 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.99465452 |
| 49 | Purine metabolism_Homo sapiens_hsa00230 | 0.98705635 |
| 50 | RNA transport_Homo sapiens_hsa03013 | 0.98287541 |
| 51 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.97332115 |
| 52 | Nicotine addiction_Homo sapiens_hsa05033 | 0.96813282 |
| 53 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.96694323 |
| 54 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.93887695 |
| 55 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.90426484 |
| 56 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.87416239 |
| 57 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.80672633 |
| 58 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.80223652 |
| 59 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.80096381 |
| 60 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.79789309 |
| 61 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.79462106 |
| 62 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.78617006 |
| 63 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.73657026 |
| 64 | Retinol metabolism_Homo sapiens_hsa00830 | 0.72689219 |
| 65 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.67005322 |
| 66 | Metabolic pathways_Homo sapiens_hsa01100 | 0.63732932 |
| 67 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.61040098 |
| 68 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.60050283 |
| 69 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.56649584 |
| 70 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.55346516 |
| 71 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.54566260 |
| 72 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.53781100 |
| 73 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.51923489 |
| 74 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.51834300 |
| 75 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.51471359 |
| 76 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.49285685 |
| 77 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.48293342 |
| 78 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.47909159 |
| 79 | Olfactory transduction_Homo sapiens_hsa04740 | 0.46430703 |
| 80 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.46319898 |
| 81 | Morphine addiction_Homo sapiens_hsa05032 | 0.43866204 |
| 82 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.43836096 |
| 83 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.40251314 |
| 84 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.40092279 |
| 85 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.39941388 |
| 86 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.39014128 |
| 87 | Taste transduction_Homo sapiens_hsa04742 | 0.35462598 |
| 88 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.35420094 |
| 89 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.33402486 |
| 90 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.33152008 |
| 91 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.32275422 |
| 92 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.31895807 |
| 93 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.30670211 |
| 94 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.28656730 |
| 95 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.28354023 |
| 96 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.27466777 |
| 97 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.24881835 |
| 98 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.23666765 |
| 99 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.23605678 |
| 100 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.23070556 |

