

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | urate metabolic process (GO:0046415) | 6.83733280 |
| 2 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 6.40989179 |
| 3 | DNA deamination (GO:0045006) | 6.35502641 |
| 4 | purine-containing compound salvage (GO:0043101) | 5.60692489 |
| 5 | histone H2A acetylation (GO:0043968) | 5.29881769 |
| 6 | spermatid nucleus differentiation (GO:0007289) | 4.96418576 |
| 7 | CENP-A containing nucleosome assembly (GO:0034080) | 4.80119114 |
| 8 | rRNA modification (GO:0000154) | 4.60579791 |
| 9 | chromatin remodeling at centromere (GO:0031055) | 4.47887945 |
| 10 | cytidine deamination (GO:0009972) | 4.42152054 |
| 11 | cytidine metabolic process (GO:0046087) | 4.42152054 |
| 12 | cytidine catabolic process (GO:0006216) | 4.42152054 |
| 13 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.31359566 |
| 14 | rRNA methylation (GO:0031167) | 4.25066875 |
| 15 | mitotic sister chromatid segregation (GO:0000070) | 4.19583318 |
| 16 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.06044737 |
| 17 | histone exchange (GO:0043486) | 4.01834804 |
| 18 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.98009626 |
| 19 | sister chromatid segregation (GO:0000819) | 3.93586610 |
| 20 | purine nucleotide salvage (GO:0032261) | 3.86500533 |
| 21 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.85563713 |
| 22 | DNA strand elongation (GO:0022616) | 3.78895785 |
| 23 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.77666463 |
| 24 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.69302423 |
| 25 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.68416685 |
| 26 | DNA replication-independent nucleosome organization (GO:0034724) | 3.68416685 |
| 27 | telomere maintenance via recombination (GO:0000722) | 3.67707697 |
| 28 | mitotic metaphase plate congression (GO:0007080) | 3.67311234 |
| 29 | ribosomal large subunit biogenesis (GO:0042273) | 3.66848135 |
| 30 | meiotic chromosome segregation (GO:0045132) | 3.64678650 |
| 31 | phosphate ion transport (GO:0006817) | 3.52243538 |
| 32 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.51605299 |
| 33 | regulation of catecholamine metabolic process (GO:0042069) | 3.50988193 |
| 34 | regulation of dopamine metabolic process (GO:0042053) | 3.50988193 |
| 35 | activated T cell proliferation (GO:0050798) | 3.50313628 |
| 36 | ATP synthesis coupled proton transport (GO:0015986) | 3.49781235 |
| 37 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.49781235 |
| 38 | purine nucleobase biosynthetic process (GO:0009113) | 3.46389521 |
| 39 | mitotic recombination (GO:0006312) | 3.41951023 |
| 40 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.36898606 |
| 41 | DNA ligation (GO:0006266) | 3.36883017 |
| 42 | kinetochore organization (GO:0051383) | 3.28621198 |
| 43 | kinetochore assembly (GO:0051382) | 3.27628989 |
| 44 | DNA topological change (GO:0006265) | 3.26612160 |
| 45 | telomere maintenance via telomere lengthening (GO:0010833) | 3.25909055 |
| 46 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.25552613 |
| 47 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.23139049 |
| 48 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.18417330 |
| 49 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.18417330 |
| 50 | behavioral response to nicotine (GO:0035095) | 3.13344531 |
| 51 | nucleobase biosynthetic process (GO:0046112) | 3.12406231 |
| 52 | deoxyribose phosphate biosynthetic process (GO:0046385) | 3.08437323 |
| 53 | 2-deoxyribonucleotide biosynthetic process (GO:0009265) | 3.08437323 |
| 54 | metaphase plate congression (GO:0051310) | 3.07269758 |
| 55 | N-acetylglucosamine metabolic process (GO:0006044) | 3.03379866 |
| 56 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.03011754 |
| 57 | lysine catabolic process (GO:0006554) | 3.02263559 |
| 58 | lysine metabolic process (GO:0006553) | 3.02263559 |
| 59 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.02064712 |
| 60 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 3.01228365 |
| 61 | deoxyribonucleotide biosynthetic process (GO:0009263) | 2.99993438 |
| 62 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.99919071 |
| 63 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.96897320 |
| 64 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.95654196 |
| 65 | protein localization to kinetochore (GO:0034501) | 2.91946925 |
| 66 | ATP-dependent chromatin remodeling (GO:0043044) | 2.91248760 |
| 67 | mismatch repair (GO:0006298) | 2.90962063 |
| 68 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.90449758 |
| 69 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.84638122 |
| 70 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.84638122 |
| 71 | positive regulation of chromosome segregation (GO:0051984) | 2.83211226 |
| 72 | organelle disassembly (GO:1903008) | 2.80570727 |
| 73 | mitotic G2 DNA damage checkpoint (GO:0007095) | 2.80207231 |
| 74 | DNA strand renaturation (GO:0000733) | 2.79229942 |
| 75 | positive regulation of megakaryocyte differentiation (GO:0045654) | 2.78865674 |
| 76 | protein homotrimerization (GO:0070207) | 2.76572914 |
| 77 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.74668319 |
| 78 | mitotic G2/M transition checkpoint (GO:0044818) | 2.72125181 |
| 79 | establishment of chromosome localization (GO:0051303) | 2.71941098 |
| 80 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 2.71031924 |
| 81 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 2.71031924 |
| 82 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 2.71031924 |
| 83 | ribonucleoprotein complex disassembly (GO:0032988) | 2.70817010 |
| 84 | aminoglycoside antibiotic metabolic process (GO:0030647) | 2.69552211 |
| 85 | spindle checkpoint (GO:0031577) | 2.69193964 |
| 86 | recombinational repair (GO:0000725) | 2.68223659 |
| 87 | protein localization to chromosome (GO:0034502) | 2.66461602 |
| 88 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.66193776 |
| 89 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.64875681 |
| 90 | regulation of exit from mitosis (GO:0007096) | 2.64645327 |
| 91 | double-strand break repair via homologous recombination (GO:0000724) | 2.64085858 |
| 92 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.63236554 |
| 93 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.63236554 |
| 94 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.63236554 |
| 95 | adenosine metabolic process (GO:0046085) | 2.62882432 |
| 96 | regulation of spindle organization (GO:0090224) | 2.62302267 |
| 97 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.60865227 |
| 98 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.60865227 |
| 99 | pseudouridine synthesis (GO:0001522) | 2.59600596 |
| 100 | DNA replication checkpoint (GO:0000076) | 2.59204629 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.13931461 |
| 2 | GATA1_22025678_ChIP-Seq_K562_Human | 6.69251402 |
| 3 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.79711422 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.38275257 |
| 5 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.38035748 |
| 6 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 4.01667345 |
| 7 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.51932854 |
| 8 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.49052149 |
| 9 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.21985580 |
| 10 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.95705967 |
| 11 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.94454020 |
| 12 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.76070665 |
| 13 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.62452616 |
| 14 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.42279878 |
| 15 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.31354596 |
| 16 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.23517422 |
| 17 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.22463933 |
| 18 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.21079667 |
| 19 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.09667218 |
| 20 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.95276384 |
| 21 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.94876151 |
| 22 | VDR_22108803_ChIP-Seq_LS180_Human | 1.94733658 |
| 23 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.92690802 |
| 24 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.90529093 |
| 25 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.87200687 |
| 26 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.87035470 |
| 27 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.72471567 |
| 28 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.68019695 |
| 29 | EWS_26573619_Chip-Seq_HEK293_Human | 1.65121554 |
| 30 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.64584464 |
| 31 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.64459051 |
| 32 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.59149025 |
| 33 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.57607982 |
| 34 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.56506900 |
| 35 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.56370373 |
| 36 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.53599491 |
| 37 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.50401330 |
| 38 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.50268293 |
| 39 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.47641467 |
| 40 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.45797862 |
| 41 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.45141802 |
| 42 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.44456464 |
| 43 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.41574605 |
| 44 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.37327333 |
| 45 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.36856055 |
| 46 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.36643795 |
| 47 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.29223988 |
| 48 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.25238913 |
| 49 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.24817079 |
| 50 | FUS_26573619_Chip-Seq_HEK293_Human | 1.23240307 |
| 51 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.22675082 |
| 52 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.20214263 |
| 53 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.16511591 |
| 54 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.13213818 |
| 55 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.13213406 |
| 56 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.08807412 |
| 57 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.08807412 |
| 58 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.07879382 |
| 59 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.07356509 |
| 60 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.06961275 |
| 61 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.06909984 |
| 62 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.06233607 |
| 63 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.05012960 |
| 64 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.04703798 |
| 65 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.04283230 |
| 66 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.03960135 |
| 67 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.02389538 |
| 68 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.00886288 |
| 69 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.99789797 |
| 70 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.99789797 |
| 71 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.98806506 |
| 72 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.98628808 |
| 73 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.98237871 |
| 74 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.97609244 |
| 75 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.93661630 |
| 76 | GATA3_26560356_Chip-Seq_TH2_Human | 0.93427775 |
| 77 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.90897078 |
| 78 | EZH2_22144423_ChIP-Seq_EOC_Human | 0.88624496 |
| 79 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.84475267 |
| 80 | NCOR_22424771_ChIP-Seq_293T_Human | 0.82329323 |
| 81 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.81754039 |
| 82 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.81677464 |
| 83 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.81570483 |
| 84 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.80712180 |
| 85 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.79895363 |
| 86 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.77068750 |
| 87 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.76598273 |
| 88 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.75545784 |
| 89 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.75017054 |
| 90 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.75001849 |
| 91 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.74622121 |
| 92 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.74038771 |
| 93 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.73986349 |
| 94 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 0.72628103 |
| 95 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.72134563 |
| 96 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.70523158 |
| 97 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.69660932 |
| 98 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.68396339 |
| 99 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.67521362 |
| 100 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.67340343 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008058_abnormal_DNA_repair | 4.17590022 |
| 2 | MP0010094_abnormal_chromosome_stability | 3.92281203 |
| 3 | MP0003111_abnormal_nucleus_morphology | 3.77186842 |
| 4 | MP0000372_irregular_coat_pigmentation | 3.52450377 |
| 5 | MP0004147_increased_porphyrin_level | 3.18471437 |
| 6 | MP0001346_abnormal_lacrimal_gland | 2.88343702 |
| 7 | MP0003693_abnormal_embryo_hatching | 2.87132491 |
| 8 | MP0009697_abnormal_copulation | 2.78460897 |
| 9 | MP0005671_abnormal_response_to | 2.72161973 |
| 10 | MP0004957_abnormal_blastocyst_morpholog | 2.68600437 |
| 11 | MP0003950_abnormal_plasma_membrane | 2.65665072 |
| 12 | MP0003077_abnormal_cell_cycle | 2.44193222 |
| 13 | MP0003878_abnormal_ear_physiology | 2.23290732 |
| 14 | MP0005377_hearing/vestibular/ear_phenot | 2.23290732 |
| 15 | MP0003806_abnormal_nucleotide_metabolis | 2.19013343 |
| 16 | MP0001348_abnormal_lacrimal_gland | 2.17785342 |
| 17 | MP0002090_abnormal_vision | 2.10260717 |
| 18 | MP0008877_abnormal_DNA_methylation | 1.90758839 |
| 19 | MP0003763_abnormal_thymus_physiology | 1.86976659 |
| 20 | MP0002938_white_spotting | 1.82333150 |
| 21 | MP0005083_abnormal_biliary_tract | 1.81400253 |
| 22 | MP0000685_abnormal_immune_system | 1.70169207 |
| 23 | MP0005645_abnormal_hypothalamus_physiol | 1.69270088 |
| 24 | MP0006072_abnormal_retinal_apoptosis | 1.68322949 |
| 25 | MP0001919_abnormal_reproductive_system | 1.68120033 |
| 26 | MP0003195_calcinosis | 1.56302797 |
| 27 | MP0005084_abnormal_gallbladder_morpholo | 1.56238340 |
| 28 | MP0002160_abnormal_reproductive_system | 1.54481827 |
| 29 | MP0002736_abnormal_nociception_after | 1.50109368 |
| 30 | MP0005551_abnormal_eye_electrophysiolog | 1.49709609 |
| 31 | MP0010234_abnormal_vibrissa_follicle | 1.49173062 |
| 32 | MP0001835_abnormal_antigen_presentation | 1.47987709 |
| 33 | MP0006035_abnormal_mitochondrial_morpho | 1.47741124 |
| 34 | MP0004808_abnormal_hematopoietic_stem | 1.45532831 |
| 35 | MP0002102_abnormal_ear_morphology | 1.43499833 |
| 36 | MP0006036_abnormal_mitochondrial_physio | 1.40899175 |
| 37 | MP0002006_tumorigenesis | 1.38817159 |
| 38 | MP0005310_abnormal_salivary_gland | 1.37447177 |
| 39 | MP0005389_reproductive_system_phenotype | 1.36383697 |
| 40 | MP0005397_hematopoietic_system_phenotyp | 1.35289099 |
| 41 | MP0001545_abnormal_hematopoietic_system | 1.35289099 |
| 42 | MP0009333_abnormal_splenocyte_physiolog | 1.34816610 |
| 43 | MP0002166_altered_tumor_susceptibility | 1.34259098 |
| 44 | MP0008057_abnormal_DNA_replication | 1.29283234 |
| 45 | MP0000015_abnormal_ear_pigmentation | 1.27196985 |
| 46 | MP0006292_abnormal_olfactory_placode | 1.23248478 |
| 47 | MP0005360_urolithiasis | 1.22858730 |
| 48 | MP0003786_premature_aging | 1.21249117 |
| 49 | MP0001929_abnormal_gametogenesis | 1.16646297 |
| 50 | MP0003252_abnormal_bile_duct | 1.11998734 |
| 51 | MP0005387_immune_system_phenotype | 1.09248270 |
| 52 | MP0001790_abnormal_immune_system | 1.09248270 |
| 53 | MP0005647_abnormal_sex_gland | 1.08499462 |
| 54 | MP0009785_altered_susceptibility_to | 1.04795053 |
| 55 | MP0001486_abnormal_startle_reflex | 1.04495076 |
| 56 | MP0005195_abnormal_posterior_eye | 1.02401101 |
| 57 | MP0008775_abnormal_heart_ventricle | 1.02163166 |
| 58 | MP0008961_abnormal_basal_metabolism | 1.01457618 |
| 59 | MP0002210_abnormal_sex_determination | 0.99956505 |
| 60 | MP0004145_abnormal_muscle_electrophysio | 0.94525752 |
| 61 | MP0003567_abnormal_fetal_cardiomyocyte | 0.94445731 |
| 62 | MP0004215_abnormal_myocardial_fiber | 0.93421450 |
| 63 | MP0003137_abnormal_impulse_conducting | 0.92477953 |
| 64 | MP0002095_abnormal_skin_pigmentation | 0.92219242 |
| 65 | MP0001145_abnormal_male_reproductive | 0.90213372 |
| 66 | MP0003880_abnormal_central_pattern | 0.86839267 |
| 67 | MP0003718_maternal_effect | 0.83690618 |
| 68 | MP0005266_abnormal_metabolism | 0.83060242 |
| 69 | MP0002405_respiratory_system_inflammati | 0.82242105 |
| 70 | MP0000653_abnormal_sex_gland | 0.82174304 |
| 71 | MP0001730_embryonic_growth_arrest | 0.81013815 |
| 72 | MP0002138_abnormal_hepatobiliary_system | 0.80940804 |
| 73 | MP0002398_abnormal_bone_marrow | 0.80576838 |
| 74 | MP0001697_abnormal_embryo_size | 0.79693160 |
| 75 | MP0001324_abnormal_eye_pigmentation | 0.79668835 |
| 76 | MP0001800_abnormal_humoral_immune | 0.79406851 |
| 77 | MP0002254_reproductive_system_inflammat | 0.78179304 |
| 78 | MP0001986_abnormal_taste_sensitivity | 0.78114977 |
| 79 | MP0005636_abnormal_mineral_homeostasis | 0.77174725 |
| 80 | MP0003698_abnormal_male_reproductive | 0.76798053 |
| 81 | MP0001819_abnormal_immune_cell | 0.75176843 |
| 82 | MP0005253_abnormal_eye_physiology | 0.73331217 |
| 83 | MP0002420_abnormal_adaptive_immunity | 0.73229140 |
| 84 | MP0003941_abnormal_skin_development | 0.71837542 |
| 85 | MP0005319_abnormal_enzyme/_coenzyme | 0.70876588 |
| 86 | MP0004019_abnormal_vitamin_homeostasis | 0.70621495 |
| 87 | MP0009379_abnormal_foot_pigmentation | 0.70368078 |
| 88 | MP0003866_abnormal_defecation | 0.69575481 |
| 89 | MP0000358_abnormal_cell_content/ | 0.69337538 |
| 90 | MP0008932_abnormal_embryonic_tissue | 0.69301003 |
| 91 | MP0000516_abnormal_urinary_system | 0.69093485 |
| 92 | MP0005367_renal/urinary_system_phenotyp | 0.69093485 |
| 93 | MP0002452_abnormal_antigen_presenting | 0.68812039 |
| 94 | MP0000427_abnormal_hair_cycle | 0.67948506 |
| 95 | MP0001119_abnormal_female_reproductive | 0.67049775 |
| 96 | MP0010678_abnormal_skin_adnexa | 0.66602929 |
| 97 | MP0001764_abnormal_homeostasis | 0.66576912 |
| 98 | MP0008007_abnormal_cellular_replicative | 0.66444040 |
| 99 | MP0005025_abnormal_response_to | 0.66431697 |
| 100 | MP0002019_abnormal_tumor_incidence | 0.66228339 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Autoimmune thrombocytopenia (HP:0001973) | 6.69159901 |
| 2 | Autoimmune hemolytic anemia (HP:0001890) | 5.50108649 |
| 3 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 5.18553648 |
| 4 | Visual hallucinations (HP:0002367) | 4.50519656 |
| 5 | Increased cerebral lipofuscin (HP:0011813) | 4.23818170 |
| 6 | Prostate neoplasm (HP:0100787) | 4.11464732 |
| 7 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 4.07061667 |
| 8 | Spastic diplegia (HP:0001264) | 3.79153859 |
| 9 | Parakeratosis (HP:0001036) | 3.75362772 |
| 10 | Generalized aminoaciduria (HP:0002909) | 3.74420348 |
| 11 | Amniotic constriction ring (HP:0009775) | 3.68888600 |
| 12 | Abnormality of placental membranes (HP:0011409) | 3.68888600 |
| 13 | Congenital stationary night blindness (HP:0007642) | 3.59688780 |
| 14 | Pendular nystagmus (HP:0012043) | 3.43557756 |
| 15 | Abnormality of the labia minora (HP:0012880) | 3.37741225 |
| 16 | Tetraparesis (HP:0002273) | 3.33203623 |
| 17 | Clubbing of toes (HP:0100760) | 3.13078548 |
| 18 | Testicular atrophy (HP:0000029) | 3.03569873 |
| 19 | Severe visual impairment (HP:0001141) | 2.88691897 |
| 20 | Abnormality of T cell physiology (HP:0011840) | 2.88444551 |
| 21 | Abnormality of the renal collecting system (HP:0004742) | 2.85578391 |
| 22 | Meckel diverticulum (HP:0002245) | 2.78567409 |
| 23 | Renal cortical cysts (HP:0000803) | 2.73216726 |
| 24 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.72266527 |
| 25 | Supernumerary spleens (HP:0009799) | 2.67732387 |
| 26 | Abnormality of the preputium (HP:0100587) | 2.66900549 |
| 27 | Agnosia (HP:0010524) | 2.66677772 |
| 28 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.65774759 |
| 29 | Abnormality of the prostate (HP:0008775) | 2.65762088 |
| 30 | Abnormality of the ileum (HP:0001549) | 2.57181253 |
| 31 | Progressive external ophthalmoplegia (HP:0000590) | 2.56811634 |
| 32 | Acute lymphatic leukemia (HP:0006721) | 2.54277416 |
| 33 | Duplicated collecting system (HP:0000081) | 2.53700257 |
| 34 | Pancreatic cysts (HP:0001737) | 2.46012841 |
| 35 | Chromsome breakage (HP:0040012) | 2.45404349 |
| 36 | Abnormality of chromosome stability (HP:0003220) | 2.45387555 |
| 37 | Dyschromatopsia (HP:0007641) | 2.41674214 |
| 38 | Pancreatic fibrosis (HP:0100732) | 2.41251151 |
| 39 | Recurrent viral infections (HP:0004429) | 2.38994040 |
| 40 | Duodenal stenosis (HP:0100867) | 2.36191652 |
| 41 | Small intestinal stenosis (HP:0012848) | 2.36191652 |
| 42 | Hypoplastic pelvis (HP:0008839) | 2.32654313 |
| 43 | Abnormality of B cell number (HP:0010975) | 2.31325142 |
| 44 | Proximal tubulopathy (HP:0000114) | 2.30167121 |
| 45 | Conjunctival hamartoma (HP:0100780) | 2.27019077 |
| 46 | Asplenia (HP:0001746) | 2.25310722 |
| 47 | Methylmalonic acidemia (HP:0002912) | 2.24218038 |
| 48 | B lymphocytopenia (HP:0010976) | 2.21115057 |
| 49 | True hermaphroditism (HP:0010459) | 2.20411099 |
| 50 | Abnormality of the renal cortex (HP:0011035) | 2.17289176 |
| 51 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 2.13649756 |
| 52 | Aplasia of the musculature (HP:0100854) | 2.09940175 |
| 53 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.09390185 |
| 54 | Myelodysplasia (HP:0002863) | 2.09076072 |
| 55 | Abolished electroretinogram (ERG) (HP:0000550) | 2.06817738 |
| 56 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.05200590 |
| 57 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.01259355 |
| 58 | Abnormality of the carotid arteries (HP:0005344) | 1.94168685 |
| 59 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.92335769 |
| 60 | Megaloblastic anemia (HP:0001889) | 1.91303276 |
| 61 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.90277013 |
| 62 | Cystic hygroma (HP:0000476) | 1.89531501 |
| 63 | Squamous cell carcinoma (HP:0002860) | 1.89500097 |
| 64 | Nausea (HP:0002018) | 1.89073602 |
| 65 | Stillbirth (HP:0003826) | 1.88813052 |
| 66 | Colon cancer (HP:0003003) | 1.87690169 |
| 67 | Abnormality of the duodenum (HP:0002246) | 1.86529113 |
| 68 | Pancytopenia (HP:0001876) | 1.86471586 |
| 69 | Abnormal number of erythroid precursors (HP:0012131) | 1.85854139 |
| 70 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.85000674 |
| 71 | Abnormality of T cells (HP:0002843) | 1.84887214 |
| 72 | Abnormal auditory evoked potentials (HP:0006958) | 1.83128635 |
| 73 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.83093785 |
| 74 | Lymphoma (HP:0002665) | 1.81736708 |
| 75 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.79321903 |
| 76 | Attenuation of retinal blood vessels (HP:0007843) | 1.78801317 |
| 77 | Sloping forehead (HP:0000340) | 1.78673374 |
| 78 | Absent thumb (HP:0009777) | 1.78107186 |
| 79 | Abnormal lung lobation (HP:0002101) | 1.77341892 |
| 80 | Gout (HP:0001997) | 1.76333335 |
| 81 | Abnormality of purine metabolism (HP:0004352) | 1.74080764 |
| 82 | Macrocytic anemia (HP:0001972) | 1.72533798 |
| 83 | Abnormality of vitamin B metabolism (HP:0004340) | 1.70950855 |
| 84 | Melanoma (HP:0002861) | 1.70732467 |
| 85 | Hyperglycinemia (HP:0002154) | 1.70422934 |
| 86 | Central scotoma (HP:0000603) | 1.70280988 |
| 87 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.70139285 |
| 88 | Pallor (HP:0000980) | 1.70006308 |
| 89 | Patellar aplasia (HP:0006443) | 1.69651441 |
| 90 | Long clavicles (HP:0000890) | 1.68180280 |
| 91 | Neoplasm of the colon (HP:0100273) | 1.67704849 |
| 92 | Decreased central vision (HP:0007663) | 1.67049856 |
| 93 | Optic nerve hypoplasia (HP:0000609) | 1.66752575 |
| 94 | Oral leukoplakia (HP:0002745) | 1.65892250 |
| 95 | Poor speech (HP:0002465) | 1.65665429 |
| 96 | Absent radius (HP:0003974) | 1.65088512 |
| 97 | Acute encephalopathy (HP:0006846) | 1.63780479 |
| 98 | Short tibia (HP:0005736) | 1.63481528 |
| 99 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.62735828 |
| 100 | Abnormality of serum amino acid levels (HP:0003112) | 1.61793867 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NEK1 | 5.80416926 |
| 2 | BUB1 | 5.49090846 |
| 3 | EIF2AK1 | 3.60201153 |
| 4 | MST4 | 3.22532063 |
| 5 | PLK4 | 2.84021433 |
| 6 | NUAK1 | 2.79655577 |
| 7 | TXK | 2.77812523 |
| 8 | VRK2 | 2.71269067 |
| 9 | ZAK | 2.51712156 |
| 10 | MAP4K1 | 2.42746005 |
| 11 | TAF1 | 2.37203379 |
| 12 | CDK19 | 2.32018480 |
| 13 | EIF2AK3 | 2.28561271 |
| 14 | TAOK3 | 2.19430169 |
| 15 | WEE1 | 2.17238213 |
| 16 | FRK | 2.02239108 |
| 17 | MAP3K12 | 1.86790112 |
| 18 | PLK3 | 1.80280743 |
| 19 | VRK1 | 1.70271680 |
| 20 | CDC7 | 1.67101752 |
| 21 | TTK | 1.63421751 |
| 22 | SMG1 | 1.59735853 |
| 23 | PLK1 | 1.53410655 |
| 24 | AURKA | 1.38192796 |
| 25 | NEK2 | 1.36244683 |
| 26 | TLK1 | 1.35735131 |
| 27 | ADRBK2 | 1.30889338 |
| 28 | CHEK2 | 1.25973225 |
| 29 | STK39 | 1.22045119 |
| 30 | STK3 | 1.20119333 |
| 31 | EIF2AK2 | 1.16801346 |
| 32 | AURKB | 1.11612521 |
| 33 | STK16 | 1.11101790 |
| 34 | BMPR2 | 0.97837661 |
| 35 | PBK | 0.95096308 |
| 36 | GRK1 | 0.92114319 |
| 37 | GRK5 | 0.89393047 |
| 38 | DYRK3 | 0.88517879 |
| 39 | CCNB1 | 0.87585295 |
| 40 | OXSR1 | 0.87447379 |
| 41 | BTK | 0.86247426 |
| 42 | STK10 | 0.80839920 |
| 43 | TNIK | 0.80719687 |
| 44 | TEC | 0.80660329 |
| 45 | MAP3K11 | 0.78187097 |
| 46 | IKBKB | 0.70086442 |
| 47 | PLK2 | 0.68827960 |
| 48 | MKNK1 | 0.66892113 |
| 49 | FGFR2 | 0.64741104 |
| 50 | PNCK | 0.62889017 |
| 51 | BRSK1 | 0.62850821 |
| 52 | CHEK1 | 0.60831686 |
| 53 | DAPK1 | 0.60006984 |
| 54 | CSNK2A1 | 0.59815432 |
| 55 | RPS6KA4 | 0.55084823 |
| 56 | BRAF | 0.54889173 |
| 57 | STK4 | 0.54219987 |
| 58 | GRK7 | 0.54210845 |
| 59 | ACVR1B | 0.51862097 |
| 60 | SYK | 0.51652921 |
| 61 | BMPR1B | 0.50763300 |
| 62 | BCKDK | 0.45911127 |
| 63 | ATR | 0.45237555 |
| 64 | WNK4 | 0.44865251 |
| 65 | PRKACB | 0.42304618 |
| 66 | DYRK2 | 0.41770076 |
| 67 | BRSK2 | 0.40998790 |
| 68 | LYN | 0.40017011 |
| 69 | TGFBR2 | 0.38806790 |
| 70 | WNK3 | 0.38771037 |
| 71 | ERBB3 | 0.37364428 |
| 72 | SRPK1 | 0.36733507 |
| 73 | CSNK2A2 | 0.36439463 |
| 74 | PASK | 0.35706646 |
| 75 | STK11 | 0.35372422 |
| 76 | MUSK | 0.34428092 |
| 77 | ATM | 0.34188083 |
| 78 | NME2 | 0.33782809 |
| 79 | CSNK1A1 | 0.32003863 |
| 80 | MKNK2 | 0.31659105 |
| 81 | INSRR | 0.30114634 |
| 82 | CDK1 | 0.29446157 |
| 83 | AKT3 | 0.29205454 |
| 84 | KDR | 0.26326623 |
| 85 | MAP4K2 | 0.26210104 |
| 86 | PIK3CG | 0.24722048 |
| 87 | PRKCD | 0.24021793 |
| 88 | PRKACA | 0.22962915 |
| 89 | TSSK6 | 0.22935707 |
| 90 | LATS1 | 0.21376547 |
| 91 | TRIM28 | 0.20921232 |
| 92 | MAP3K14 | 0.20023126 |
| 93 | RPS6KB1 | 0.19708698 |
| 94 | MAPKAPK5 | 0.19460524 |
| 95 | ITK | 0.18460284 |
| 96 | LCK | 0.18451030 |
| 97 | CAMK2D | 0.18400891 |
| 98 | CAMK2G | 0.18229570 |
| 99 | ADRBK1 | 0.17897014 |
| 100 | DAPK3 | 0.17496518 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Mismatch repair_Homo sapiens_hsa03430 | 4.59687098 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 4.30554990 |
| 3 | DNA replication_Homo sapiens_hsa03030 | 4.05821552 |
| 4 | Homologous recombination_Homo sapiens_hsa03440 | 3.89199478 |
| 5 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.76340772 |
| 6 | Ribosome_Homo sapiens_hsa03010 | 2.59346513 |
| 7 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.56139754 |
| 8 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.39412687 |
| 9 | Spliceosome_Homo sapiens_hsa03040 | 2.05816507 |
| 10 | Protein export_Homo sapiens_hsa03060 | 2.03444950 |
| 11 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.92686643 |
| 12 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.79117548 |
| 13 | Parkinsons disease_Homo sapiens_hsa05012 | 1.77424480 |
| 14 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.68438293 |
| 15 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.65259512 |
| 16 | RNA degradation_Homo sapiens_hsa03018 | 1.62618760 |
| 17 | Asthma_Homo sapiens_hsa05310 | 1.61816377 |
| 18 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.58403678 |
| 19 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.58272432 |
| 20 | Cell cycle_Homo sapiens_hsa04110 | 1.56625014 |
| 21 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.53612939 |
| 22 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.51299541 |
| 23 | Basal transcription factors_Homo sapiens_hsa03022 | 1.51297258 |
| 24 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.47413270 |
| 25 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.44947847 |
| 26 | Base excision repair_Homo sapiens_hsa03410 | 1.28832179 |
| 27 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.26977883 |
| 28 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.24740276 |
| 29 | Phototransduction_Homo sapiens_hsa04744 | 1.23332962 |
| 30 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.21195612 |
| 31 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.19610765 |
| 32 | RNA transport_Homo sapiens_hsa03013 | 1.18323096 |
| 33 | RNA polymerase_Homo sapiens_hsa03020 | 1.17814329 |
| 34 | Allograft rejection_Homo sapiens_hsa05330 | 1.17244399 |
| 35 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.12555991 |
| 36 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.12018810 |
| 37 | Renin-angiotensin system_Homo sapiens_hsa04614 | 1.09688932 |
| 38 | Purine metabolism_Homo sapiens_hsa00230 | 1.08886488 |
| 39 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.08805133 |
| 40 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.07381306 |
| 41 | Huntingtons disease_Homo sapiens_hsa05016 | 1.06571992 |
| 42 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.02426563 |
| 43 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.99470966 |
| 44 | Alzheimers disease_Homo sapiens_hsa05010 | 0.99303622 |
| 45 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.98925405 |
| 46 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.98520517 |
| 47 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.95198783 |
| 48 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.94891457 |
| 49 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.94228900 |
| 50 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.90439647 |
| 51 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.88692026 |
| 52 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.87498501 |
| 53 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.83041343 |
| 54 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.82961953 |
| 55 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.82453512 |
| 56 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.82145922 |
| 57 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.81738456 |
| 58 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.80996594 |
| 59 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.78675759 |
| 60 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.77894955 |
| 61 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.73873613 |
| 62 | Taste transduction_Homo sapiens_hsa04742 | 0.72831018 |
| 63 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.71717451 |
| 64 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.70182905 |
| 65 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.67668608 |
| 66 | Retinol metabolism_Homo sapiens_hsa00830 | 0.64770161 |
| 67 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.64285669 |
| 68 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.63500577 |
| 69 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.60749532 |
| 70 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.60659268 |
| 71 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.60441123 |
| 72 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.59961369 |
| 73 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.59102259 |
| 74 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.57431971 |
| 75 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.56041125 |
| 76 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.55844755 |
| 77 | Metabolic pathways_Homo sapiens_hsa01100 | 0.50596405 |
| 78 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.50357027 |
| 79 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.50326564 |
| 80 | Olfactory transduction_Homo sapiens_hsa04740 | 0.47488158 |
| 81 | Alcoholism_Homo sapiens_hsa05034 | 0.42917292 |
| 82 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.41266346 |
| 83 | HTLV-I infection_Homo sapiens_hsa05166 | 0.40588984 |
| 84 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.40259812 |
| 85 | Mineral absorption_Homo sapiens_hsa04978 | 0.37506883 |
| 86 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.36964753 |
| 87 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.36432064 |
| 88 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.36295528 |
| 89 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.35622472 |
| 90 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.35115856 |
| 91 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.34559404 |
| 92 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.34047246 |
| 93 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.33274313 |
| 94 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.32626761 |
| 95 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.32267954 |
| 96 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.28562926 |
| 97 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.27898590 |
| 98 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.26147942 |
| 99 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.23499810 |
| 100 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.23420969 |

