

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 6.20562296 |
| 2 | chaperone-mediated protein transport (GO:0072321) | 5.61746235 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.28263238 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 5.28263238 |
| 5 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.97530710 |
| 6 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.61418585 |
| 7 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.61418585 |
| 8 | NADH dehydrogenase complex assembly (GO:0010257) | 4.61418585 |
| 9 | otic vesicle formation (GO:0030916) | 4.45644587 |
| 10 | ribosomal small subunit assembly (GO:0000028) | 4.43279543 |
| 11 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.34394745 |
| 12 | protein complex biogenesis (GO:0070271) | 4.32469807 |
| 13 | neuron fate determination (GO:0048664) | 4.29758322 |
| 14 | protein-cofactor linkage (GO:0018065) | 4.13485129 |
| 15 | maturation of SSU-rRNA (GO:0030490) | 4.03468413 |
| 16 | respiratory electron transport chain (GO:0022904) | 4.02533279 |
| 17 | behavioral response to nicotine (GO:0035095) | 3.96279320 |
| 18 | electron transport chain (GO:0022900) | 3.95243223 |
| 19 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.91072652 |
| 20 | viral transcription (GO:0019083) | 3.81704229 |
| 21 | translational termination (GO:0006415) | 3.74378544 |
| 22 | cotranslational protein targeting to membrane (GO:0006613) | 3.72884864 |
| 23 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.71626281 |
| 24 | peptidyl-histidine modification (GO:0018202) | 3.69373198 |
| 25 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.60057499 |
| 26 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.57567489 |
| 27 | inner mitochondrial membrane organization (GO:0007007) | 3.55697236 |
| 28 | protein targeting to ER (GO:0045047) | 3.50056373 |
| 29 | platelet dense granule organization (GO:0060155) | 3.43231936 |
| 30 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.42727583 |
| 31 | spinal cord association neuron differentiation (GO:0021527) | 3.42290833 |
| 32 | proteasome assembly (GO:0043248) | 3.42258654 |
| 33 | termination of RNA polymerase III transcription (GO:0006386) | 3.40213576 |
| 34 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.40213576 |
| 35 | kinetochore assembly (GO:0051382) | 3.39624843 |
| 36 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.36734778 |
| 37 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.36734778 |
| 38 | protein localization to endoplasmic reticulum (GO:0070972) | 3.32598395 |
| 39 | intracellular protein transmembrane import (GO:0044743) | 3.32359584 |
| 40 | protein neddylation (GO:0045116) | 3.31016152 |
| 41 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.29012311 |
| 42 | neuron fate specification (GO:0048665) | 3.25178041 |
| 43 | maturation of 5.8S rRNA (GO:0000460) | 3.19790317 |
| 44 | pseudouridine synthesis (GO:0001522) | 3.18351194 |
| 45 | DNA double-strand break processing (GO:0000729) | 3.17600261 |
| 46 | translational elongation (GO:0006414) | 3.15755075 |
| 47 | DNA deamination (GO:0045006) | 3.14767047 |
| 48 | DNA damage response, detection of DNA damage (GO:0042769) | 3.08011484 |
| 49 | kinetochore organization (GO:0051383) | 3.07133120 |
| 50 | ribosomal small subunit biogenesis (GO:0042274) | 3.07128711 |
| 51 | DNA demethylation (GO:0080111) | 3.02934442 |
| 52 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.02533427 |
| 53 | translation (GO:0006412) | 3.00634780 |
| 54 | ATP biosynthetic process (GO:0006754) | 2.98624173 |
| 55 | epithelial cilium movement (GO:0003351) | 2.96675212 |
| 56 | reciprocal DNA recombination (GO:0035825) | 2.92879256 |
| 57 | reciprocal meiotic recombination (GO:0007131) | 2.92879256 |
| 58 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.92257769 |
| 59 | cellular protein complex disassembly (GO:0043624) | 2.88026451 |
| 60 | neurotransmitter catabolic process (GO:0042135) | 2.87892748 |
| 61 | cell proliferation in forebrain (GO:0021846) | 2.87464009 |
| 62 | translational initiation (GO:0006413) | 2.87119910 |
| 63 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.85780358 |
| 64 | chromatin remodeling at centromere (GO:0031055) | 2.84137526 |
| 65 | viral life cycle (GO:0019058) | 2.82868421 |
| 66 | CENP-A containing nucleosome assembly (GO:0034080) | 2.82249395 |
| 67 | ubiquinone metabolic process (GO:0006743) | 2.81860917 |
| 68 | regulation of mitochondrial translation (GO:0070129) | 2.80775865 |
| 69 | protein targeting to mitochondrion (GO:0006626) | 2.80436362 |
| 70 | protein localization to mitochondrion (GO:0070585) | 2.78439310 |
| 71 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.77169360 |
| 72 | cellular component biogenesis (GO:0044085) | 2.76742673 |
| 73 | ubiquinone biosynthetic process (GO:0006744) | 2.75656216 |
| 74 | protein K6-linked ubiquitination (GO:0085020) | 2.75600204 |
| 75 | GTP biosynthetic process (GO:0006183) | 2.72097488 |
| 76 | establishment of protein localization to mitochondrion (GO:0072655) | 2.71522057 |
| 77 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.70432727 |
| 78 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 2.70264288 |
| 79 | somite development (GO:0061053) | 2.68502270 |
| 80 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.67126549 |
| 81 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 2.66231795 |
| 82 | CTP biosynthetic process (GO:0006241) | 2.64860737 |
| 83 | CTP metabolic process (GO:0046036) | 2.64860737 |
| 84 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.63952984 |
| 85 | replication fork processing (GO:0031297) | 2.62346965 |
| 86 | organelle disassembly (GO:1903008) | 2.62107102 |
| 87 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.61777079 |
| 88 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.60495031 |
| 89 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.59925502 |
| 90 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.59925502 |
| 91 | DNA ligation (GO:0006266) | 2.59440774 |
| 92 | amine catabolic process (GO:0009310) | 2.55522137 |
| 93 | cellular biogenic amine catabolic process (GO:0042402) | 2.55522137 |
| 94 | negative regulation of ligase activity (GO:0051352) | 2.55055416 |
| 95 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.55055416 |
| 96 | synaptic transmission, cholinergic (GO:0007271) | 2.53411431 |
| 97 | hydrogen ion transmembrane transport (GO:1902600) | 2.52433375 |
| 98 | protein complex disassembly (GO:0043241) | 2.50791577 |
| 99 | cilium movement (GO:0003341) | 2.50237260 |
| 100 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.50049615 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.25996137 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.87437534 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.75337909 |
| 4 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.23533446 |
| 5 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 3.10197633 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.06796824 |
| 7 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.88543344 |
| 8 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.86995124 |
| 9 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.84753276 |
| 10 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.81860101 |
| 11 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.68709917 |
| 12 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.60648051 |
| 13 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.58489047 |
| 14 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.53191975 |
| 15 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.51509808 |
| 16 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.49870815 |
| 17 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.39594240 |
| 18 | VDR_22108803_ChIP-Seq_LS180_Human | 2.28405953 |
| 19 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.15305290 |
| 20 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.10223346 |
| 21 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.09950905 |
| 22 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.00467672 |
| 23 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.97445163 |
| 24 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.96285906 |
| 25 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.94804092 |
| 26 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.93397948 |
| 27 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.91864964 |
| 28 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.86888542 |
| 29 | EWS_26573619_Chip-Seq_HEK293_Human | 1.85605529 |
| 30 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.80076600 |
| 31 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.69858671 |
| 32 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.67400001 |
| 33 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.65972431 |
| 34 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.60900976 |
| 35 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.58917988 |
| 36 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.58740516 |
| 37 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.57704402 |
| 38 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.54713972 |
| 39 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.53065840 |
| 40 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.44799507 |
| 41 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.44241442 |
| 42 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.41986793 |
| 43 | FUS_26573619_Chip-Seq_HEK293_Human | 1.40762780 |
| 44 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.40338308 |
| 45 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.39807015 |
| 46 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.37952575 |
| 47 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.37254053 |
| 48 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.35966088 |
| 49 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.34910826 |
| 50 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.32246620 |
| 51 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.31463539 |
| 52 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.31263676 |
| 53 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.31249440 |
| 54 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.31161932 |
| 55 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.30651240 |
| 56 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.30637222 |
| 57 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.29943318 |
| 58 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.28285886 |
| 59 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.26130331 |
| 60 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.25384112 |
| 61 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.25161434 |
| 62 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.24657669 |
| 63 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.23818906 |
| 64 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.16064730 |
| 65 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.15958073 |
| 66 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.15268194 |
| 67 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.12585903 |
| 68 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.12358488 |
| 69 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.11105819 |
| 70 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.10289545 |
| 71 | NCOR_22424771_ChIP-Seq_293T_Human | 1.08022000 |
| 72 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.07727874 |
| 73 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.07299841 |
| 74 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.05473211 |
| 75 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.04529800 |
| 76 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.02919344 |
| 77 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.02871996 |
| 78 | P300_19829295_ChIP-Seq_ESCs_Human | 1.00563290 |
| 79 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.99546865 |
| 80 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.98998889 |
| 81 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.98048484 |
| 82 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.97269803 |
| 83 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.96722403 |
| 84 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.96364128 |
| 85 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.95846505 |
| 86 | AR_20517297_ChIP-Seq_VCAP_Human | 0.93706257 |
| 87 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.92772157 |
| 88 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.92005452 |
| 89 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.87544102 |
| 90 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.86023641 |
| 91 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.85541316 |
| 92 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.83139137 |
| 93 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.82466850 |
| 94 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.82466850 |
| 95 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.81634040 |
| 96 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.80954464 |
| 97 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.80822680 |
| 98 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.80175336 |
| 99 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.79451791 |
| 100 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.78537168 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 7.71780920 |
| 2 | MP0003136_yellow_coat_color | 3.49595916 |
| 3 | MP0009379_abnormal_foot_pigmentation | 3.45018247 |
| 4 | MP0002277_abnormal_respiratory_mucosa | 2.92392640 |
| 5 | MP0008789_abnormal_olfactory_epithelium | 2.67247820 |
| 6 | MP0002653_abnormal_ependyma_morphology | 2.65125948 |
| 7 | MP0006276_abnormal_autonomic_nervous | 2.63595338 |
| 8 | MP0005499_abnormal_olfactory_system | 2.61770607 |
| 9 | MP0005394_taste/olfaction_phenotype | 2.61770607 |
| 10 | MP0001529_abnormal_vocalization | 2.45374345 |
| 11 | MP0003880_abnormal_central_pattern | 2.42630517 |
| 12 | MP0001293_anophthalmia | 2.40578936 |
| 13 | MP0002102_abnormal_ear_morphology | 2.28882618 |
| 14 | MP0000049_abnormal_middle_ear | 2.18401884 |
| 15 | MP0002163_abnormal_gland_morphology | 2.01316154 |
| 16 | MP0003938_abnormal_ear_development | 1.99215746 |
| 17 | MP0000372_irregular_coat_pigmentation | 1.83446170 |
| 18 | MP0004142_abnormal_muscle_tone | 1.81200828 |
| 19 | MP0002938_white_spotting | 1.70176477 |
| 20 | MP0001485_abnormal_pinna_reflex | 1.65619549 |
| 21 | MP0008058_abnormal_DNA_repair | 1.56124812 |
| 22 | MP0005257_abnormal_intraocular_pressure | 1.49017686 |
| 23 | MP0008877_abnormal_DNA_methylation | 1.45933451 |
| 24 | MP0001286_abnormal_eye_development | 1.45928731 |
| 25 | MP0005646_abnormal_pituitary_gland | 1.45646889 |
| 26 | MP0002736_abnormal_nociception_after | 1.44647472 |
| 27 | MP0006072_abnormal_retinal_apoptosis | 1.40964849 |
| 28 | MP0003890_abnormal_embryonic-extraembry | 1.40114848 |
| 29 | MP0006035_abnormal_mitochondrial_morpho | 1.34038914 |
| 30 | MP0009697_abnormal_copulation | 1.32342618 |
| 31 | MP0003186_abnormal_redox_activity | 1.31256301 |
| 32 | MP0004133_heterotaxia | 1.30893038 |
| 33 | MP0000778_abnormal_nervous_system | 1.30529520 |
| 34 | MP0003693_abnormal_embryo_hatching | 1.29382123 |
| 35 | MP0003195_calcinosis | 1.29144465 |
| 36 | MP0010094_abnormal_chromosome_stability | 1.26857149 |
| 37 | MP0005379_endocrine/exocrine_gland_phen | 1.23466714 |
| 38 | MP0002822_catalepsy | 1.23381107 |
| 39 | MP0008995_early_reproductive_senescence | 1.23313459 |
| 40 | MP0000631_abnormal_neuroendocrine_gland | 1.22292649 |
| 41 | MP0004147_increased_porphyrin_level | 1.13907960 |
| 42 | MP0009745_abnormal_behavioral_response | 1.12466353 |
| 43 | MP0003567_abnormal_fetal_cardiomyocyte | 1.12412917 |
| 44 | MP0003786_premature_aging | 1.11711096 |
| 45 | MP0003122_maternal_imprinting | 1.11105877 |
| 46 | MP0001968_abnormal_touch/_nociception | 1.10742346 |
| 47 | MP0006036_abnormal_mitochondrial_physio | 1.09441241 |
| 48 | MP0002095_abnormal_skin_pigmentation | 1.07371682 |
| 49 | MP0002233_abnormal_nose_morphology | 1.06991241 |
| 50 | MP0003787_abnormal_imprinting | 1.06437601 |
| 51 | MP0000569_abnormal_digit_pigmentation | 1.06318290 |
| 52 | MP0008932_abnormal_embryonic_tissue | 1.04519395 |
| 53 | MP0002557_abnormal_social/conspecific_i | 1.03998565 |
| 54 | MP0004957_abnormal_blastocyst_morpholog | 1.03589302 |
| 55 | MP0003937_abnormal_limbs/digits/tail_de | 1.02092128 |
| 56 | MP0001299_abnormal_eye_distance/ | 1.01981863 |
| 57 | MP0002090_abnormal_vision | 1.01655970 |
| 58 | MP0005551_abnormal_eye_electrophysiolog | 1.00643730 |
| 59 | MP0005085_abnormal_gallbladder_physiolo | 1.00459341 |
| 60 | MP0002697_abnormal_eye_size | 1.00038315 |
| 61 | MP0000026_abnormal_inner_ear | 0.99185880 |
| 62 | MP0001984_abnormal_olfaction | 0.98558802 |
| 63 | MP0001905_abnormal_dopamine_level | 0.96040427 |
| 64 | MP0008775_abnormal_heart_ventricle | 0.95375670 |
| 65 | MP0008872_abnormal_physiological_respon | 0.95202297 |
| 66 | MP0002210_abnormal_sex_determination | 0.94667521 |
| 67 | MP0002752_abnormal_somatic_nervous | 0.94406213 |
| 68 | MP0003755_abnormal_palate_morphology | 0.93594334 |
| 69 | MP0005195_abnormal_posterior_eye | 0.91771099 |
| 70 | MP0001486_abnormal_startle_reflex | 0.91711904 |
| 71 | MP0003137_abnormal_impulse_conducting | 0.90701326 |
| 72 | MP0004085_abnormal_heartbeat | 0.90571076 |
| 73 | MP0000647_abnormal_sebaceous_gland | 0.90387062 |
| 74 | MP0003121_genomic_imprinting | 0.90024908 |
| 75 | MP0002837_dystrophic_cardiac_calcinosis | 0.89692369 |
| 76 | MP0003111_abnormal_nucleus_morphology | 0.88838314 |
| 77 | MP0003077_abnormal_cell_cycle | 0.88753074 |
| 78 | MP0004145_abnormal_muscle_electrophysio | 0.87834468 |
| 79 | MP0009046_muscle_twitch | 0.87026684 |
| 80 | MP0002638_abnormal_pupillary_reflex | 0.86633221 |
| 81 | MP0002733_abnormal_thermal_nociception | 0.84662721 |
| 82 | MP0002234_abnormal_pharynx_morphology | 0.82959074 |
| 83 | MP0003119_abnormal_digestive_system | 0.82929062 |
| 84 | MP0002272_abnormal_nervous_system | 0.81316276 |
| 85 | MP0003861_abnormal_nervous_system | 0.79597059 |
| 86 | MP0002111_abnormal_tail_morphology | 0.79421868 |
| 87 | MP0002184_abnormal_innervation | 0.78406167 |
| 88 | MP0005391_vision/eye_phenotype | 0.77225640 |
| 89 | MP0005248_abnormal_Harderian_gland | 0.76920014 |
| 90 | MP0004885_abnormal_endolymph | 0.76897949 |
| 91 | MP0002160_abnormal_reproductive_system | 0.76560638 |
| 92 | MP0002282_abnormal_trachea_morphology | 0.75606394 |
| 93 | MP0005084_abnormal_gallbladder_morpholo | 0.75532600 |
| 94 | MP0000955_abnormal_spinal_cord | 0.75473979 |
| 95 | MP0000613_abnormal_salivary_gland | 0.75308533 |
| 96 | MP0001764_abnormal_homeostasis | 0.74478416 |
| 97 | MP0000653_abnormal_sex_gland | 0.73922379 |
| 98 | MP0005377_hearing/vestibular/ear_phenot | 0.73295276 |
| 99 | MP0003878_abnormal_ear_physiology | 0.73295276 |
| 100 | MP0002751_abnormal_autonomic_nervous | 0.72561290 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 5.36706571 |
| 2 | Septo-optic dysplasia (HP:0100842) | 5.10096771 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.78495754 |
| 4 | Acute encephalopathy (HP:0006846) | 4.69360294 |
| 5 | Progressive macrocephaly (HP:0004481) | 4.32891739 |
| 6 | Pancreatic fibrosis (HP:0100732) | 3.94563096 |
| 7 | Mitochondrial inheritance (HP:0001427) | 3.93378806 |
| 8 | Optic nerve hypoplasia (HP:0000609) | 3.66296201 |
| 9 | Pancreatic cysts (HP:0001737) | 3.66223818 |
| 10 | Abnormality of the labia minora (HP:0012880) | 3.63859667 |
| 11 | Maternal diabetes (HP:0009800) | 3.55825212 |
| 12 | Pendular nystagmus (HP:0012043) | 3.55370752 |
| 13 | Hepatocellular necrosis (HP:0001404) | 3.52561308 |
| 14 | Hepatic necrosis (HP:0002605) | 3.49641775 |
| 15 | Increased CSF lactate (HP:0002490) | 3.48194264 |
| 16 | Cerebral edema (HP:0002181) | 3.46432659 |
| 17 | Optic disc pallor (HP:0000543) | 3.45597630 |
| 18 | Oligodactyly (hands) (HP:0001180) | 3.30470064 |
| 19 | Reticulocytopenia (HP:0001896) | 3.25550856 |
| 20 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 3.24084324 |
| 21 | Absent septum pellucidum (HP:0001331) | 3.03849941 |
| 22 | Supernumerary spleens (HP:0009799) | 2.88461953 |
| 23 | Molar tooth sign on MRI (HP:0002419) | 2.80948610 |
| 24 | Abnormality of midbrain morphology (HP:0002418) | 2.80948610 |
| 25 | Stenosis of the external auditory canal (HP:0000402) | 2.79266870 |
| 26 | True hermaphroditism (HP:0010459) | 2.77735806 |
| 27 | Abnormality of the septum pellucidum (HP:0007375) | 2.73312184 |
| 28 | Increased hepatocellular lipid droplets (HP:0006565) | 2.58442300 |
| 29 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.45533832 |
| 30 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.45533832 |
| 31 | Leukodystrophy (HP:0002415) | 2.41555857 |
| 32 | Medial flaring of the eyebrow (HP:0010747) | 2.40606017 |
| 33 | Oligodactyly (HP:0012165) | 2.37657523 |
| 34 | Abnormal ciliary motility (HP:0012262) | 2.36364814 |
| 35 | Patellar aplasia (HP:0006443) | 2.32380953 |
| 36 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.31927695 |
| 37 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.28834572 |
| 38 | X-linked dominant inheritance (HP:0001423) | 2.20173241 |
| 39 | Asplenia (HP:0001746) | 2.19592576 |
| 40 | Generalized aminoaciduria (HP:0002909) | 2.19533478 |
| 41 | Anophthalmia (HP:0000528) | 2.18550799 |
| 42 | Meckel diverticulum (HP:0002245) | 2.14133695 |
| 43 | Increased serum lactate (HP:0002151) | 2.10517471 |
| 44 | Sclerocornea (HP:0000647) | 2.10076528 |
| 45 | Esophageal atresia (HP:0002032) | 2.09521558 |
| 46 | Horseshoe kidney (HP:0000085) | 2.09457200 |
| 47 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 2.07915394 |
| 48 | Exercise intolerance (HP:0003546) | 2.06994037 |
| 49 | Lactic acidosis (HP:0003128) | 2.06868651 |
| 50 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.05692080 |
| 51 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.05692080 |
| 52 | Nephronophthisis (HP:0000090) | 2.05196887 |
| 53 | Cystic liver disease (HP:0006706) | 2.04357112 |
| 54 | Lipid accumulation in hepatocytes (HP:0006561) | 2.03841856 |
| 55 | Delayed CNS myelination (HP:0002188) | 2.00514608 |
| 56 | Median cleft lip (HP:0000161) | 1.97491575 |
| 57 | Abnormality of the renal cortex (HP:0011035) | 1.97267877 |
| 58 | Abnormal hair whorl (HP:0010721) | 1.96250317 |
| 59 | Abnormality of the ileum (HP:0001549) | 1.94928391 |
| 60 | Intestinal atresia (HP:0011100) | 1.93277344 |
| 61 | Increased serum pyruvate (HP:0003542) | 1.92721250 |
| 62 | Type 2 muscle fiber atrophy (HP:0003554) | 1.92433009 |
| 63 | Polydipsia (HP:0001959) | 1.91298799 |
| 64 | Abnormal drinking behavior (HP:0030082) | 1.91298799 |
| 65 | Macrocytic anemia (HP:0001972) | 1.89592264 |
| 66 | Split foot (HP:0001839) | 1.87945061 |
| 67 | Respiratory failure (HP:0002878) | 1.87042264 |
| 68 | Optic nerve coloboma (HP:0000588) | 1.86655648 |
| 69 | Absent thumb (HP:0009777) | 1.86653233 |
| 70 | Lethargy (HP:0001254) | 1.86181931 |
| 71 | Anencephaly (HP:0002323) | 1.86021885 |
| 72 | Renal Fanconi syndrome (HP:0001994) | 1.85206728 |
| 73 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.82817512 |
| 74 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.82590422 |
| 75 | Abnormality of the renal medulla (HP:0100957) | 1.82001071 |
| 76 | Congenital primary aphakia (HP:0007707) | 1.81306477 |
| 77 | Gait imbalance (HP:0002141) | 1.80823206 |
| 78 | Abnormality of the diencephalon (HP:0010662) | 1.79042337 |
| 79 | Methylmalonic acidemia (HP:0002912) | 1.77373836 |
| 80 | Hypoplasia of the pons (HP:0012110) | 1.77242873 |
| 81 | Occipital encephalocele (HP:0002085) | 1.76609528 |
| 82 | Preaxial hand polydactyly (HP:0001177) | 1.75268205 |
| 83 | Increased intramyocellular lipid droplets (HP:0012240) | 1.74474839 |
| 84 | Absent radius (HP:0003974) | 1.73950709 |
| 85 | Constricted visual fields (HP:0001133) | 1.73522695 |
| 86 | Triphalangeal thumb (HP:0001199) | 1.72458469 |
| 87 | Progressive cerebellar ataxia (HP:0002073) | 1.72327744 |
| 88 | Postaxial foot polydactyly (HP:0001830) | 1.71904146 |
| 89 | Absent forearm bone (HP:0003953) | 1.70963047 |
| 90 | Aplasia involving forearm bones (HP:0009822) | 1.70963047 |
| 91 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.70578542 |
| 92 | Depressed nasal ridge (HP:0000457) | 1.70120119 |
| 93 | Congenital hepatic fibrosis (HP:0002612) | 1.69157750 |
| 94 | Lissencephaly (HP:0001339) | 1.67345220 |
| 95 | Vaginal atresia (HP:0000148) | 1.66359636 |
| 96 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.64909882 |
| 97 | 3-Methylglutaconic aciduria (HP:0003535) | 1.64676845 |
| 98 | Holoprosencephaly (HP:0001360) | 1.64584534 |
| 99 | Synostosis involving the elbow (HP:0003938) | 1.64495382 |
| 100 | Humeroradial synostosis (HP:0003041) | 1.64495382 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SRPK1 | 4.04976252 |
| 2 | WNK4 | 2.96272157 |
| 3 | CASK | 2.72857785 |
| 4 | BUB1 | 2.65760448 |
| 5 | PLK4 | 2.49299527 |
| 6 | BCKDK | 2.45707323 |
| 7 | WNK3 | 2.44158787 |
| 8 | MAP4K2 | 2.43427498 |
| 9 | NUAK1 | 2.36432715 |
| 10 | PINK1 | 2.28369245 |
| 11 | MKNK2 | 2.22240535 |
| 12 | ZAK | 2.11271900 |
| 13 | EPHA4 | 2.04320536 |
| 14 | VRK2 | 1.94807907 |
| 15 | TRIM28 | 1.85221484 |
| 16 | TIE1 | 1.82710361 |
| 17 | STK16 | 1.79837070 |
| 18 | NEK1 | 1.76679958 |
| 19 | GRK1 | 1.75580520 |
| 20 | BCR | 1.65788811 |
| 21 | DYRK2 | 1.62153916 |
| 22 | STK39 | 1.60199120 |
| 23 | MKNK1 | 1.55417053 |
| 24 | VRK1 | 1.45427070 |
| 25 | PBK | 1.45073386 |
| 26 | PLK2 | 1.40866305 |
| 27 | OXSR1 | 1.38927700 |
| 28 | LATS1 | 1.37453526 |
| 29 | TNIK | 1.36057694 |
| 30 | ADRBK2 | 1.26495131 |
| 31 | CDC7 | 1.23798008 |
| 32 | PLK3 | 1.20476355 |
| 33 | AURKA | 1.18048066 |
| 34 | AURKB | 1.17525142 |
| 35 | PLK1 | 1.15748383 |
| 36 | CCNB1 | 1.12996313 |
| 37 | TTK | 1.02763547 |
| 38 | UHMK1 | 1.02234124 |
| 39 | EIF2AK3 | 0.96949834 |
| 40 | TLK1 | 0.95913497 |
| 41 | NEK2 | 0.95186152 |
| 42 | PIM2 | 0.94506391 |
| 43 | DYRK3 | 0.94471544 |
| 44 | PRKCE | 0.92430239 |
| 45 | MAP2K7 | 0.90901012 |
| 46 | TAF1 | 0.90395107 |
| 47 | WEE1 | 0.88256585 |
| 48 | PRKCG | 0.86007631 |
| 49 | MAP3K4 | 0.83541857 |
| 50 | STK4 | 0.83490373 |
| 51 | MAPK13 | 0.83191054 |
| 52 | PRKCI | 0.81131192 |
| 53 | TNK2 | 0.80565235 |
| 54 | TSSK6 | 0.77913552 |
| 55 | CSNK1G3 | 0.77611385 |
| 56 | CSNK2A1 | 0.77150396 |
| 57 | EPHB2 | 0.76315739 |
| 58 | BRAF | 0.73078863 |
| 59 | CSNK1G2 | 0.65854247 |
| 60 | ADRBK1 | 0.64594820 |
| 61 | BMPR1B | 0.63530043 |
| 62 | STK3 | 0.61575248 |
| 63 | INSRR | 0.61514702 |
| 64 | CSNK1G1 | 0.58876582 |
| 65 | EIF2AK1 | 0.58166546 |
| 66 | NME1 | 0.58140564 |
| 67 | CSNK2A2 | 0.57844640 |
| 68 | MAP2K4 | 0.57835038 |
| 69 | BRSK1 | 0.57387027 |
| 70 | PRKCQ | 0.56959084 |
| 71 | CHEK2 | 0.53949169 |
| 72 | CSNK1A1 | 0.53399161 |
| 73 | PNCK | 0.53374331 |
| 74 | CSNK1E | 0.51553534 |
| 75 | ATR | 0.50321908 |
| 76 | MINK1 | 0.49563410 |
| 77 | GRK7 | 0.48657335 |
| 78 | STK38L | 0.47145548 |
| 79 | CDK19 | 0.45519433 |
| 80 | FGFR1 | 0.45501542 |
| 81 | ABL2 | 0.45144413 |
| 82 | CAMK2A | 0.43841062 |
| 83 | TAOK3 | 0.43772479 |
| 84 | TXK | 0.43040349 |
| 85 | PIK3CA | 0.42667100 |
| 86 | PRKG1 | 0.42570556 |
| 87 | CAMK2B | 0.42419003 |
| 88 | LIMK1 | 0.41428054 |
| 89 | SGK223 | 0.40037204 |
| 90 | SGK494 | 0.40037204 |
| 91 | KDR | 0.37531550 |
| 92 | ERBB3 | 0.35769864 |
| 93 | PRKACA | 0.35760686 |
| 94 | PRKACB | 0.35322422 |
| 95 | DAPK2 | 0.32733933 |
| 96 | RPS6KA5 | 0.32642537 |
| 97 | ATM | 0.32503167 |
| 98 | ERBB2 | 0.32004393 |
| 99 | OBSCN | 0.30899809 |
| 100 | CAMK2D | 0.30687854 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.18960123 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.17303837 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.72094543 |
| 4 | Proteasome_Homo sapiens_hsa03050 | 3.26334906 |
| 5 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 3.24163187 |
| 6 | Protein export_Homo sapiens_hsa03060 | 3.20688341 |
| 7 | Huntingtons disease_Homo sapiens_hsa05016 | 2.62546676 |
| 8 | Basal transcription factors_Homo sapiens_hsa03022 | 2.50958371 |
| 9 | RNA polymerase_Homo sapiens_hsa03020 | 2.45389678 |
| 10 | Mismatch repair_Homo sapiens_hsa03430 | 2.42840323 |
| 11 | Alzheimers disease_Homo sapiens_hsa05010 | 2.39240285 |
| 12 | Homologous recombination_Homo sapiens_hsa03440 | 2.23822654 |
| 13 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.19548100 |
| 14 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.01503284 |
| 15 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.89033849 |
| 16 | DNA replication_Homo sapiens_hsa03030 | 1.84602519 |
| 17 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.80867613 |
| 18 | Base excision repair_Homo sapiens_hsa03410 | 1.79648778 |
| 19 | RNA degradation_Homo sapiens_hsa03018 | 1.74820111 |
| 20 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.74069584 |
| 21 | Spliceosome_Homo sapiens_hsa03040 | 1.67297267 |
| 22 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.57156351 |
| 23 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.51442794 |
| 24 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.43126746 |
| 25 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.40555588 |
| 26 | Nicotine addiction_Homo sapiens_hsa05033 | 1.33734136 |
| 27 | Peroxisome_Homo sapiens_hsa04146 | 1.33356502 |
| 28 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.31701004 |
| 29 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.31564096 |
| 30 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.24707936 |
| 31 | RNA transport_Homo sapiens_hsa03013 | 1.22091204 |
| 32 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.21430680 |
| 33 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.15884633 |
| 34 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.05124945 |
| 35 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.04941215 |
| 36 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.02029005 |
| 37 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.01689144 |
| 38 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.93204771 |
| 39 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.91621160 |
| 40 | Purine metabolism_Homo sapiens_hsa00230 | 0.91531357 |
| 41 | Phototransduction_Homo sapiens_hsa04744 | 0.90544383 |
| 42 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.86570442 |
| 43 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.83153021 |
| 44 | Cell cycle_Homo sapiens_hsa04110 | 0.82064895 |
| 45 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.81496644 |
| 46 | Metabolic pathways_Homo sapiens_hsa01100 | 0.78939173 |
| 47 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.74764150 |
| 48 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.74228123 |
| 49 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.72287416 |
| 50 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.72224307 |
| 51 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.71676081 |
| 52 | Retinol metabolism_Homo sapiens_hsa00830 | 0.70805133 |
| 53 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.70397332 |
| 54 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.69453607 |
| 55 | Taste transduction_Homo sapiens_hsa04742 | 0.67871753 |
| 56 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.67816298 |
| 57 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.67522356 |
| 58 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.65717741 |
| 59 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.63132825 |
| 60 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.61855611 |
| 61 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.58789079 |
| 62 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.58647718 |
| 63 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.58305228 |
| 64 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.57951854 |
| 65 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.56365124 |
| 66 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.56008392 |
| 67 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.54289083 |
| 68 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.53904682 |
| 69 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.52983114 |
| 70 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.51463463 |
| 71 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.51153260 |
| 72 | GABAergic synapse_Homo sapiens_hsa04727 | 0.49298638 |
| 73 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.48368577 |
| 74 | Olfactory transduction_Homo sapiens_hsa04740 | 0.46718746 |
| 75 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.46611113 |
| 76 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.43994298 |
| 77 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.42532955 |
| 78 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.41457689 |
| 79 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.40938657 |
| 80 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.40835711 |
| 81 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.40834222 |
| 82 | Morphine addiction_Homo sapiens_hsa05032 | 0.40500206 |
| 83 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.38559031 |
| 84 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.38534912 |
| 85 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.37189085 |
| 86 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.36215813 |
| 87 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.35816916 |
| 88 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.35544378 |
| 89 | Carbon metabolism_Homo sapiens_hsa01200 | 0.33769289 |
| 90 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.32110684 |
| 91 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.31537435 |
| 92 | Circadian entrainment_Homo sapiens_hsa04713 | 0.26283202 |
| 93 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.26277797 |
| 94 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.25517472 |
| 95 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.23882702 |
| 96 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.23680235 |
| 97 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.23366410 |
| 98 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.23089067 |
| 99 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.22504574 |
| 100 | Sulfur relay system_Homo sapiens_hsa04122 | 0.21534750 |

