HMGCLL1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle exocytosis (GO:0016079)5.08102906
2positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.07860295
3regulation of short-term neuronal synaptic plasticity (GO:0048172)4.84305465
4vocalization behavior (GO:0071625)4.63900184
5neuron cell-cell adhesion (GO:0007158)4.55709002
6protein localization to synapse (GO:0035418)4.48476147
7righting reflex (GO:0060013)4.45480576
8regulation of synaptic vesicle exocytosis (GO:2000300)4.38749076
9inositol phosphate catabolic process (GO:0071545)4.30229456
10regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.26988054
11positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.19269287
12regulation of inhibitory postsynaptic membrane potential (GO:0060080)4.14657744
13regulation of synaptic vesicle transport (GO:1902803)4.12532291
14glutamate secretion (GO:0014047)4.07438034
15phosphorylated carbohydrate dephosphorylation (GO:0046838)3.89413284
16inositol phosphate dephosphorylation (GO:0046855)3.89413284
17insulin secretion (GO:0030073)3.87843806
18regulation of glutamate receptor signaling pathway (GO:1900449)3.87619408
19neurotransmitter-gated ion channel clustering (GO:0072578)3.87083482
20detection of calcium ion (GO:0005513)3.84890415
21neurotransmitter secretion (GO:0007269)3.83092960
22response to pheromone (GO:0019236)3.81605039
23behavioral response to ethanol (GO:0048149)3.81321496
24synaptic vesicle maturation (GO:0016188)3.78512023
25negative regulation of cytosolic calcium ion concentration (GO:0051481)3.70802568
26regulation of hexokinase activity (GO:1903299)3.70774378
27regulation of glucokinase activity (GO:0033131)3.70774378
28regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.67793085
29nucleobase catabolic process (GO:0046113)3.66386420
30locomotory exploration behavior (GO:0035641)3.62497226
31pyrimidine nucleobase catabolic process (GO:0006208)3.60838976
32ionotropic glutamate receptor signaling pathway (GO:0035235)3.59392147
33neuron-neuron synaptic transmission (GO:0007270)3.59261887
34neuronal action potential propagation (GO:0019227)3.58114583
35glutamate receptor signaling pathway (GO:0007215)3.57226743
36gamma-aminobutyric acid signaling pathway (GO:0007214)3.54671020
37positive regulation of action potential (GO:0045760)3.52533332
38synaptic transmission, glutamatergic (GO:0035249)3.52240070
39synaptic vesicle endocytosis (GO:0048488)3.50951945
40neuron fate determination (GO:0048664)3.44903642
41membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.43505611
42positive regulation of synapse maturation (GO:0090129)3.42101660
43synaptic vesicle docking involved in exocytosis (GO:0016081)3.33439211
44postsynaptic membrane organization (GO:0001941)3.32094387
45regulation of vesicle fusion (GO:0031338)3.31944043
46exploration behavior (GO:0035640)3.30030142
47proline transport (GO:0015824)3.28286449
48neuron recognition (GO:0008038)3.27566396
49endocrine pancreas development (GO:0031018)3.25172668
50neurotransmitter transport (GO:0006836)3.25018222
51negative regulation of synaptic transmission, GABAergic (GO:0032229)3.24850183
52G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.24223714
53regulation of calcium ion-dependent exocytosis (GO:0017158)3.23984136
54protein localization to cilium (GO:0061512)3.23783399
55fear response (GO:0042596)3.23518227
56presynaptic membrane assembly (GO:0097105)3.21279449
57polyol catabolic process (GO:0046174)3.21227369
58negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.19898693
59synapse assembly (GO:0007416)3.19599343
60regulation of type B pancreatic cell apoptotic process (GO:2000674)3.15848294
61regulation of neuronal synaptic plasticity (GO:0048168)3.14970771
62auditory behavior (GO:0031223)3.14844344
63positive regulation of synaptic transmission, GABAergic (GO:0032230)3.14579906
64synaptic vesicle transport (GO:0048489)3.13871677
65establishment of synaptic vesicle localization (GO:0097480)3.13871677
66response to auditory stimulus (GO:0010996)3.13660647
67regulation of synaptic transmission, glutamatergic (GO:0051966)3.12274805
68regulation of long-term neuronal synaptic plasticity (GO:0048169)3.12025378
69nitric oxide mediated signal transduction (GO:0007263)3.11735611
70innervation (GO:0060384)3.10500326
71regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.10135176
72retinal ganglion cell axon guidance (GO:0031290)3.09944293
73regulation of synapse structural plasticity (GO:0051823)3.09591858
74regulation of cAMP-dependent protein kinase activity (GO:2000479)3.06587551
75axonal fasciculation (GO:0007413)3.05732871
76regulation of dopamine uptake involved in synaptic transmission (GO:0051584)3.05044012
77regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)3.05044012
78regulation of synaptic transmission, GABAergic (GO:0032228)3.04738293
79gamma-aminobutyric acid transport (GO:0015812)3.04209509
80positive regulation of insulin secretion (GO:0032024)3.02161581
81membrane hyperpolarization (GO:0060081)3.01215634
82regulation of postsynaptic membrane potential (GO:0060078)3.00531206
83negative regulation of dendrite development (GO:2000171)2.99433487
84regulation of excitatory postsynaptic membrane potential (GO:0060079)2.99054908
85transmission of nerve impulse (GO:0019226)2.98368921
86glycerophospholipid catabolic process (GO:0046475)2.98143299
87layer formation in cerebral cortex (GO:0021819)2.96700048
88behavioral fear response (GO:0001662)2.95189389
89behavioral defense response (GO:0002209)2.95189389
90response to histamine (GO:0034776)2.95174062
91long-term synaptic potentiation (GO:0060291)2.94660759
92regulation of neurotransmitter levels (GO:0001505)2.91895562
93cell migration in hindbrain (GO:0021535)2.91276673
94mating behavior (GO:0007617)2.91266220
95nonmotile primary cilium assembly (GO:0035058)2.91254738
96long-term memory (GO:0007616)2.91180518
97positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.90963588
98cellular potassium ion homeostasis (GO:0030007)2.89446992
99positive regulation of synapse assembly (GO:0051965)2.88050066
100positive regulation of membrane potential (GO:0045838)2.87320376
101startle response (GO:0001964)2.87212302
102presynaptic membrane organization (GO:0097090)2.87035927
103dendritic spine morphogenesis (GO:0060997)2.86695131
104negative regulation of calcium ion-dependent exocytosis (GO:0045955)2.85711233
105mechanosensory behavior (GO:0007638)2.82307723
106regulation of synapse maturation (GO:0090128)2.81979130
107glycosphingolipid biosynthetic process (GO:0006688)2.80959330
108cerebellar Purkinje cell differentiation (GO:0021702)2.80939045
109peptide hormone secretion (GO:0030072)2.79734607
110striatum development (GO:0021756)2.79035610
111prepulse inhibition (GO:0060134)2.78886336
112negative regulation of norepinephrine secretion (GO:0010700)2.78605006
113neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.78141866
114membrane depolarization during action potential (GO:0086010)2.77772335
115response to dietary excess (GO:0002021)2.77050292
116regulation of neurotransmitter transport (GO:0051588)2.76055820
117cAMP-mediated signaling (GO:0019933)2.76019642
118regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.75894009
119synapse organization (GO:0050808)2.75578513
120potassium ion export (GO:0071435)2.75366736
121establishment of vesicle localization (GO:0051650)2.75291794
122regulation of neurotransmitter secretion (GO:0046928)2.75089524
123synaptic transmission (GO:0007268)2.73925271
124positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.72492491
125regulation of synapse assembly (GO:0051963)2.72377839
126signal peptide processing (GO:0006465)2.71865045
127regulation of insulin secretion (GO:0050796)2.71631887
128peptide secretion (GO:0002790)2.71134167
129positive regulation of peptide hormone secretion (GO:0090277)2.69627931
130behavioral response to nicotine (GO:0035095)2.69315918
131regulation of action potential (GO:0098900)2.66805908
132epithelial cell fate commitment (GO:0072148)2.66537760
133positive regulation of mitochondrial fission (GO:0090141)2.65186173
134positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:003572.64631488
135positive regulation of glycolytic process (GO:0045821)2.63372568
136establishment of melanosome localization (GO:0032401)2.62750543
137calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.62105324
138positive regulation of peptide secretion (GO:0002793)2.61709819
139neuronal action potential (GO:0019228)2.58856206
140lactate metabolic process (GO:0006089)2.58808120
141brain morphogenesis (GO:0048854)2.58111487
142dendritic spine organization (GO:0097061)2.56017738
143peptide hormone processing (GO:0016486)2.55059231
144melanosome transport (GO:0032402)2.54044967
145regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.50799847
146signal release (GO:0023061)2.49930959
147calcium ion import (GO:0070509)2.49026905
148intraciliary transport (GO:0042073)2.48187075
149regulation of peptide hormone secretion (GO:0090276)2.48037014
150establishment of pigment granule localization (GO:0051905)2.47576735
151protein targeting to Golgi (GO:0000042)2.46945874
152alanine transport (GO:0032328)2.44996180
153regulation of neurotransmitter uptake (GO:0051580)2.44034349
154dentate gyrus development (GO:0021542)2.43863762
155regulation of peptide secretion (GO:0002791)2.42572037
156chemosensory behavior (GO:0007635)2.40618641
157serotonin metabolic process (GO:0042428)2.40500519
158establishment of protein localization to Golgi (GO:0072600)2.39599491
159pigment granule transport (GO:0051904)2.38577148
160spinal cord motor neuron differentiation (GO:0021522)2.38199772
161auditory receptor cell differentiation (GO:0042491)2.37129771
162regulation of feeding behavior (GO:0060259)2.36994941
163positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.36573364
164protein localization to Golgi apparatus (GO:0034067)2.36268359

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.20130867
2FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse4.03621956
3GBX2_23144817_ChIP-Seq_PC3_Human3.89858579
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.69876804
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.61387633
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.55341903
7REST_21632747_ChIP-Seq_MESCs_Mouse2.54024892
8EZH2_27304074_Chip-Seq_ESCs_Mouse2.29200786
9NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.28795511
10CTBP2_25329375_ChIP-Seq_LNCAP_Human2.21205402
11SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.20825558
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.19922305
13SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.17721085
14EZH2_18974828_ChIP-Seq_MESCs_Mouse2.16822325
15RNF2_18974828_ChIP-Seq_MESCs_Mouse2.16822325
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.13343331
17EED_16625203_ChIP-ChIP_MESCs_Mouse2.12592060
18SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.11538388
19REST_18959480_ChIP-ChIP_MESCs_Mouse2.09725471
20MTF2_20144788_ChIP-Seq_MESCs_Mouse2.08578555
21EZH2_27294783_Chip-Seq_ESCs_Mouse2.00893928
22BMI1_23680149_ChIP-Seq_NPCS_Mouse2.00827798
23CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.98910475
24TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.93878034
25* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.93335023
26SUZ12_27294783_Chip-Seq_ESCs_Mouse1.88589530
27RARB_27405468_Chip-Seq_BRAIN_Mouse1.88261703
28GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.87466808
29BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.86617361
30RNF2_27304074_Chip-Seq_ESCs_Mouse1.85458250
31SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.85246547
32CTBP1_25329375_ChIP-Seq_LNCAP_Human1.84052985
33SMAD4_21799915_ChIP-Seq_A2780_Human1.80705220
34TAF15_26573619_Chip-Seq_HEK293_Human1.79622121
35POU3F2_20337985_ChIP-ChIP_501MEL_Human1.77205560
36GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.74727357
37P300_19829295_ChIP-Seq_ESCs_Human1.72773154
38FLI1_27457419_Chip-Seq_LIVER_Mouse1.71965309
39DROSHA_22980978_ChIP-Seq_HELA_Human1.69332412
40ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.67939004
41IGF1R_20145208_ChIP-Seq_DFB_Human1.67820670
42PIAS1_25552417_ChIP-Seq_VCAP_Human1.66027086
43RNF2_27304074_Chip-Seq_NSC_Mouse1.60614989
44PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.60599683
45SMAD_19615063_ChIP-ChIP_OVARY_Human1.59042998
46CBX2_27304074_Chip-Seq_ESCs_Mouse1.55939511
47AR_25329375_ChIP-Seq_VCAP_Human1.53133612
48* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.48380548
49RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.48163408
50* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.45889774
51AR_21572438_ChIP-Seq_LNCaP_Human1.45329794
52* STAT3_23295773_ChIP-Seq_U87_Human1.42813566
53RBPJ_22232070_ChIP-Seq_NCS_Mouse1.42576880
54FUS_26573619_Chip-Seq_HEK293_Human1.42013879
55NR3C1_23031785_ChIP-Seq_PC12_Mouse1.41517874
56SOX2_21211035_ChIP-Seq_LN229_Gbm1.40441017
57IKZF1_21737484_ChIP-ChIP_HCT116_Human1.40429725
58SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.40233980
59SMAD3_21741376_ChIP-Seq_EPCs_Human1.36938794
60PCGF2_27294783_Chip-Seq_ESCs_Mouse1.36920739
61OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.36535504
62VDR_22108803_ChIP-Seq_LS180_Human1.35174387
63CBP_20019798_ChIP-Seq_JUKART_Human1.30963877
64IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.30963877
65HTT_18923047_ChIP-ChIP_STHdh_Human1.28478947
66PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.26874273
67RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.26232794
68ZNF274_21170338_ChIP-Seq_K562_Hela1.25619616
69SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.25143674
70NANOG_18555785_Chip-Seq_ESCs_Mouse1.25036785
71* TCF4_23295773_ChIP-Seq_U87_Human1.24978174
72YAP1_20516196_ChIP-Seq_MESCs_Mouse1.24160505
73* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.22775111
74TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.21438156
75P53_22387025_ChIP-Seq_ESCs_Mouse1.21242648
76TAL1_26923725_Chip-Seq_HPCs_Mouse1.21111148
77TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.20679310
78TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.19516783
79EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.18357599
80* MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.17815204
81SUZ12_27294783_Chip-Seq_NPCs_Mouse1.17739697
82CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16992527
83KLF5_20875108_ChIP-Seq_MESCs_Mouse1.16117139
84TP53_22573176_ChIP-Seq_HFKS_Human1.15991701
85* AR_19668381_ChIP-Seq_PC3_Human1.15683434
86RUNX2_22187159_ChIP-Seq_PCA_Human1.15584898
87NR3C1_21868756_ChIP-Seq_MCF10A_Human1.14247546
88* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.13163561
89POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.13108401
90TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13108401
91HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.11290767
92RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.10993560
93MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.10302142
94RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.09278377
95NFE2_27457419_Chip-Seq_LIVER_Mouse1.08993384
96ER_23166858_ChIP-Seq_MCF-7_Human1.08935658
97CMYC_18555785_Chip-Seq_ESCs_Mouse1.08685876
98FLI1_21867929_ChIP-Seq_TH2_Mouse1.08385524
99EWS_26573619_Chip-Seq_HEK293_Human1.07907712
100KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.07426557
101E2F1_18555785_Chip-Seq_ESCs_Mouse1.07050124
102ZNF217_24962896_ChIP-Seq_MCF-7_Human1.06984878
103P53_22127205_ChIP-Seq_FIBROBLAST_Human1.06292173
104TCF4_22108803_ChIP-Seq_LS180_Human1.05463796
105PRDM14_20953172_ChIP-Seq_ESCs_Human1.05254975
106STAT3_18555785_Chip-Seq_ESCs_Mouse1.04612969
107AHR_22903824_ChIP-Seq_MCF-7_Human1.04529004
108CDX2_19796622_ChIP-Seq_MESCs_Mouse1.03964271
109BCAT_22108803_ChIP-Seq_LS180_Human1.03889082
110JUN_21703547_ChIP-Seq_K562_Human1.03270599
111RING1B_27294783_Chip-Seq_ESCs_Mouse1.03128427
112SUZ12_18555785_Chip-Seq_ESCs_Mouse1.02766978
113CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.02326306
114FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.02273205
115EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.01752253
116SMAD3_21741376_ChIP-Seq_ESCs_Human1.01489840
117EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.00764275
118EZH2_27294783_Chip-Seq_NPCs_Mouse1.00264081
119SOX2_19829295_ChIP-Seq_ESCs_Human0.99634071
120NANOG_19829295_ChIP-Seq_ESCs_Human0.99634071
121EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.99296230
122ARNT_22903824_ChIP-Seq_MCF-7_Human0.98654842
123TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94055962
124LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93990026
125KDM2B_26808549_Chip-Seq_REH_Human0.93868043
126SOX9_26525672_Chip-Seq_HEART_Mouse0.93367505

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.29275773
2MP0003880_abnormal_central_pattern3.77154868
3MP0003635_abnormal_synaptic_transmissio3.43448225
4MP0004270_analgesia3.19064187
5MP0002063_abnormal_learning/memory/cond2.81338797
6MP0010386_abnormal_urinary_bladder2.77884365
7MP0009745_abnormal_behavioral_response2.70968145
8MP0006276_abnormal_autonomic_nervous2.66672123
9MP0001968_abnormal_touch/_nociception2.66125019
10MP0001529_abnormal_vocalization2.65306080
11MP0002734_abnormal_mechanical_nocicepti2.61652678
12MP0005423_abnormal_somatic_nervous2.51211206
13MP0002064_seizures2.49553949
14MP0002572_abnormal_emotion/affect_behav2.48476841
15MP0002736_abnormal_nociception_after2.39991083
16MP0009046_muscle_twitch2.34729564
17MP0002272_abnormal_nervous_system2.19872317
18MP0001486_abnormal_startle_reflex2.18781627
19MP0002909_abnormal_adrenal_gland2.14359527
20MP0005646_abnormal_pituitary_gland2.06189911
21MP0002733_abnormal_thermal_nociception2.03069176
22MP0002735_abnormal_chemical_nociception2.02623533
23MP0002184_abnormal_innervation1.97702903
24MP0001188_hyperpigmentation1.96123152
25MP0009780_abnormal_chondrocyte_physiolo1.95403687
26MP0001501_abnormal_sleep_pattern1.94287862
27MP0001440_abnormal_grooming_behavior1.92219055
28MP0001970_abnormal_pain_threshold1.86620536
29MP0000569_abnormal_digit_pigmentation1.85781641
30MP0002067_abnormal_sensory_capabilities1.82906455
31MP0006072_abnormal_retinal_apoptosis1.82862107
32MP0005645_abnormal_hypothalamus_physiol1.82586243
33MP0004043_abnormal_pH_regulation1.81008960
34MP0003195_calcinosis1.76924796
35MP0001984_abnormal_olfaction1.76680302
36MP0000778_abnormal_nervous_system1.76043416
37MP0001905_abnormal_dopamine_level1.74505546
38MP0003787_abnormal_imprinting1.73805485
39MP0005386_behavior/neurological_phenoty1.73300942
40MP0004924_abnormal_behavior1.73300942
41MP0002822_catalepsy1.70914257
42MP0002557_abnormal_social/conspecific_i1.67388273
43MP0003122_maternal_imprinting1.66356341
44MP0002638_abnormal_pupillary_reflex1.61130292
45MP0002163_abnormal_gland_morphology1.60740026
46MP0004885_abnormal_endolymph1.58697955
47MP0001502_abnormal_circadian_rhythm1.56543406
48MP0000631_abnormal_neuroendocrine_gland1.53853233
49MP0002102_abnormal_ear_morphology1.50331179
50MP0006292_abnormal_olfactory_placode1.43844053
51MP0000013_abnormal_adipose_tissue1.40506264
52MP0004811_abnormal_neuron_physiology1.38305773
53MP0005551_abnormal_eye_electrophysiolog1.35534518
54MP0002882_abnormal_neuron_morphology1.35377193
55MP0002139_abnormal_hepatobiliary_system1.35086379
56MP0000955_abnormal_spinal_cord1.34821960
57MP0008569_lethality_at_weaning1.33218818
58MP0010234_abnormal_vibrissa_follicle1.30058542
59MP0003879_abnormal_hair_cell1.23668305
60MP0004858_abnormal_nervous_system1.22812661
61MP0002066_abnormal_motor_capabilities/c1.21811483
62MP0000516_abnormal_urinary_system1.20324543
63MP0005367_renal/urinary_system_phenotyp1.20324543
64MP0002090_abnormal_vision1.17837964
65MP0004133_heterotaxia1.16460634
66MP0002928_abnormal_bile_duct1.16345354
67MP0002078_abnormal_glucose_homeostasis1.14908425
68MP0002837_dystrophic_cardiac_calcinosis1.08912967
69MP0002938_white_spotting1.08756511
70MP0002152_abnormal_brain_morphology1.08127486
71MP0005253_abnormal_eye_physiology1.07761360
72MP0004147_increased_porphyrin_level1.06342045
73MP0005220_abnormal_exocrine_pancreas1.02070124
74MP0003329_amyloid_beta_deposits1.01800948
75MP0004142_abnormal_muscle_tone1.00751868
76MP0003121_genomic_imprinting0.98124471
77MP0005448_abnormal_energy_balance0.97535851
78MP0005084_abnormal_gallbladder_morpholo0.96386289
79MP0003283_abnormal_digestive_organ0.95636595
80MP0002876_abnormal_thyroid_physiology0.94205995
81MP0004215_abnormal_myocardial_fiber0.94064883
82MP0001756_abnormal_urination0.93594389
83MP0002752_abnormal_somatic_nervous0.90351474
84MP0003183_abnormal_peptide_metabolism0.88962979
85MP0003011_delayed_dark_adaptation0.88572284
86MP0000639_abnormal_adrenal_gland0.88184939
87MP0005187_abnormal_penis_morphology0.88157658
88MP0004085_abnormal_heartbeat0.86729941
89MP0003953_abnormal_hormone_level0.85701813
90MP0005394_taste/olfaction_phenotype0.85227116
91MP0005499_abnormal_olfactory_system0.85227116
92MP0002069_abnormal_eating/drinking_beha0.84796254
93MP0004145_abnormal_muscle_electrophysio0.84192790
94MP0000427_abnormal_hair_cycle0.83867162
95MP0010329_abnormal_lipoprotein_level0.83482236
96MP0001963_abnormal_hearing_physiology0.82808273
97MP0002229_neurodegeneration0.82552865
98MP0004233_abnormal_muscle_weight0.82420933
99MP0005535_abnormal_body_temperature0.82246961
100MP0005379_endocrine/exocrine_gland_phen0.82218138
101MP0001986_abnormal_taste_sensitivity0.82176608
102MP0001664_abnormal_digestion0.82108289
103MP0002751_abnormal_autonomic_nervous0.81735607
104MP0001944_abnormal_pancreas_morphology0.80436275
105MP0005332_abnormal_amino_acid0.76677356
106MP0008877_abnormal_DNA_methylation0.76302582
107MP0004742_abnormal_vestibular_system0.75920184
108MP0000462_abnormal_digestive_system0.73593100
109MP0003631_nervous_system_phenotype0.73438278
110MP0003137_abnormal_impulse_conducting0.73222933
111MP0004019_abnormal_vitamin_homeostasis0.72991247
112MP0001485_abnormal_pinna_reflex0.72784046
113MP0003634_abnormal_glial_cell0.71426428
114MP0000003_abnormal_adipose_tissue0.71005907
115MP0000678_abnormal_parathyroid_gland0.70796902
116MP0003633_abnormal_nervous_system0.70314863
117MP0003861_abnormal_nervous_system0.70012963
118MP0008260_abnormal_autophagy0.69051587
119MP0003632_abnormal_nervous_system0.68238051
120MP0002693_abnormal_pancreas_physiology0.66477533
121MP0000026_abnormal_inner_ear0.65620956
122MP0001299_abnormal_eye_distance/0.65577621
123MP0000538_abnormal_urinary_bladder0.64653553
124MP0002234_abnormal_pharynx_morphology0.64223955
125MP0005248_abnormal_Harderian_gland0.64003585
126MP0003890_abnormal_embryonic-extraembry0.63005919
127MP0008872_abnormal_physiological_respon0.62474327
128MP0003123_paternal_imprinting0.62165951

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.63913136
2Atonic seizures (HP:0010819)4.82442993
3Hyperinsulinemic hypoglycemia (HP:0000825)4.30487922
4Myokymia (HP:0002411)4.18851074
5Febrile seizures (HP:0002373)4.08219412
6Hypoglycemic coma (HP:0001325)4.03207651
7Focal seizures (HP:0007359)4.02269492
8Epileptic encephalopathy (HP:0200134)3.93160036
9Hypoglycemic seizures (HP:0002173)3.92990904
10Visual hallucinations (HP:0002367)3.86352082
11Absence seizures (HP:0002121)3.73621752
12Ketoacidosis (HP:0001993)3.52568265
13Progressive cerebellar ataxia (HP:0002073)3.52198230
14Decreased circulating renin level (HP:0003351)3.40036493
15Large for gestational age (HP:0001520)3.32736073
16Generalized tonic-clonic seizures (HP:0002069)3.21238065
17Dialeptic seizures (HP:0011146)3.07327693
18Methylmalonic acidemia (HP:0002912)3.01504213
19Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.98939793
20Intestinal atresia (HP:0011100)2.95529714
21Hypothermia (HP:0002045)2.91711854
22Abnormal hair whorl (HP:0010721)2.90404345
23Abnormality of the labia minora (HP:0012880)2.82051886
24Hyperglycemia (HP:0003074)2.81582714
25Abnormality of vitamin B metabolism (HP:0004340)2.72643800
26Broad-based gait (HP:0002136)2.70462448
27Limb dystonia (HP:0002451)2.68319682
28Insulin-resistant diabetes mellitus (HP:0000831)2.67899151
29Excessive salivation (HP:0003781)2.66805581
30Drooling (HP:0002307)2.66805581
31Progressive macrocephaly (HP:0004481)2.63788106
32Epileptiform EEG discharges (HP:0011182)2.60350122
33Ankle clonus (HP:0011448)2.59276060
34EEG with generalized epileptiform discharges (HP:0011198)2.54845349
35Hyperactive renin-angiotensin system (HP:0000841)2.51979224
36Nephronophthisis (HP:0000090)2.50719183
37Amblyopia (HP:0000646)2.49359611
38Depression (HP:0000716)2.47291385
39Supranuclear gaze palsy (HP:0000605)2.46780474
40Failure to thrive in infancy (HP:0001531)2.46732716
41Truncal ataxia (HP:0002078)2.46258043
42Enlarged penis (HP:0000040)2.45149113
43Gait imbalance (HP:0002141)2.44406017
44Urinary bladder sphincter dysfunction (HP:0002839)2.44261716
45Polyphagia (HP:0002591)2.42859715
46Hyperventilation (HP:0002883)2.42008704
47Pheochromocytoma (HP:0002666)2.41484368
48Acute necrotizing encephalopathy (HP:0006965)2.40953032
49Muscular hypotonia of the trunk (HP:0008936)2.39570589
50Chronic bronchitis (HP:0004469)2.38350362
51Degeneration of the lateral corticospinal tracts (HP:0002314)2.37955047
52Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.37955047
53Agitation (HP:0000713)2.37788155
54Impaired vibration sensation in the lower limbs (HP:0002166)2.35912288
55Symptomatic seizures (HP:0011145)2.35594386
56Ketosis (HP:0001946)2.34539369
57Late onset (HP:0003584)2.34387696
58Pancreatic cysts (HP:0001737)2.34226022
59Hypsarrhythmia (HP:0002521)2.34194244
60Progressive inability to walk (HP:0002505)2.33366699
61Abnormality of the pancreatic islet cells (HP:0006476)2.32000242
62Abnormality of endocrine pancreas physiology (HP:0012093)2.32000242
63Abnormality of calcium-phosphate metabolism (HP:0100530)2.31532178
64Poor eye contact (HP:0000817)2.29222907
65Gaze-evoked nystagmus (HP:0000640)2.28409514
66Abnormal eating behavior (HP:0100738)2.28116438
67Methylmalonic aciduria (HP:0012120)2.25422800
68Blue irides (HP:0000635)2.24388598
69Genetic anticipation (HP:0003743)2.23328255
70Abnormality of vitamin metabolism (HP:0100508)2.23151592
71Pancreatic fibrosis (HP:0100732)2.21324344
72Hemiparesis (HP:0001269)2.21313477
73Anxiety (HP:0000739)2.19463520
74Dysdiadochokinesis (HP:0002075)2.17673614
75Hypomagnesemia (HP:0002917)2.16863277
76Scanning speech (HP:0002168)2.16819089
77Hepatic necrosis (HP:0002605)2.15354150
78Action tremor (HP:0002345)2.13803620
79Prolonged QT interval (HP:0001657)2.10923602
80Congenital primary aphakia (HP:0007707)2.09283989
81Medial flaring of the eyebrow (HP:0010747)2.07548690
82Poor suck (HP:0002033)2.06826685
83Fetal akinesia sequence (HP:0001989)2.06756749
84Abnormality of the metopic suture (HP:0005556)2.06346024
85Urinary urgency (HP:0000012)2.05747666
86Abnormality of aromatic amino acid family metabolism (HP:0004338)2.05547128
87Absent speech (HP:0001344)2.05531655
88Papillary thyroid carcinoma (HP:0002895)2.04821082
89Mitochondrial inheritance (HP:0001427)2.02807466
90Neuroendocrine neoplasm (HP:0100634)2.02738738
91Central scotoma (HP:0000603)2.02687903
92Prominent metopic ridge (HP:0005487)2.01235004
93Abnormality of the renal medulla (HP:0100957)2.00554156
94Abnormal rod and cone electroretinograms (HP:0008323)2.00000253
95Mutism (HP:0002300)1.99575056
96Intention tremor (HP:0002080)1.99348778
97Abnormal social behavior (HP:0012433)1.99114558
98Impaired social interactions (HP:0000735)1.99114558
99Inability to walk (HP:0002540)1.98613599
100Postural tremor (HP:0002174)1.98586231
101Molar tooth sign on MRI (HP:0002419)1.98087072
102Abnormality of midbrain morphology (HP:0002418)1.98087072
103Abnormality of macular pigmentation (HP:0008002)1.97024357
104Abnormality of the renal cortex (HP:0011035)1.96579993
105Abnormal mitochondria in muscle tissue (HP:0008316)1.96535979
106Type II lissencephaly (HP:0007260)1.96012261
107Nephrogenic diabetes insipidus (HP:0009806)1.95555004
108Congenital malformation of the right heart (HP:0011723)1.95161567
109Double outlet right ventricle (HP:0001719)1.95161567
110Torticollis (HP:0000473)1.94229432
111Abnormality of salivation (HP:0100755)1.94190597
112Hepatoblastoma (HP:0002884)1.92172156
113Spastic gait (HP:0002064)1.91660655
114True hermaphroditism (HP:0010459)1.91629744
115Menstrual irregularities (HP:0000858)1.91120451
116Dysmetria (HP:0001310)1.90119869
117Poor coordination (HP:0002370)1.89629368
118Aplasia/Hypoplasia of the lens (HP:0008063)1.88773608
119Genital tract atresia (HP:0001827)1.88032711
120Hypoventilation (HP:0002791)1.87417658
121Esotropia (HP:0000565)1.86948842
122Hyperkalemia (HP:0002153)1.86379704
123Abnormality of the fovea (HP:0000493)1.84944095
124Clonus (HP:0002169)1.84726354
125Glycosuria (HP:0003076)1.83285741
126Abnormality of urine glucose concentration (HP:0011016)1.83285741
127Abnormal drinking behavior (HP:0030082)1.81708352
128Polydipsia (HP:0001959)1.81708352
129Vaginal atresia (HP:0000148)1.80039627
130Epidermoid cyst (HP:0200040)1.79908668
131Acute encephalopathy (HP:0006846)1.79291222
132Thyroid carcinoma (HP:0002890)1.78113901
133Impaired smooth pursuit (HP:0007772)1.78018900
134Specific learning disability (HP:0001328)1.77944381
135Increased CSF lactate (HP:0002490)1.77627595
136Hyperthyroidism (HP:0000836)1.77351575
137Generalized myoclonic seizures (HP:0002123)1.77138371
138Renal cortical cysts (HP:0000803)1.76304429
139Papilledema (HP:0001085)1.74587270
140Labial hypoplasia (HP:0000066)1.74384585
141Impaired vibratory sensation (HP:0002495)1.74155620
142Termporal pattern (HP:0011008)1.73798272
143Insidious onset (HP:0003587)1.73798272
144Diplopia (HP:0000651)1.72343432
145Abnormality of binocular vision (HP:0011514)1.72343432
146Narrow nasal bridge (HP:0000446)1.71808315
147Aplasia/Hypoplasia of the fovea (HP:0008060)1.71456345
148Hypoplasia of the fovea (HP:0007750)1.71456345
149Focal dystonia (HP:0004373)1.70918176
150Anteriorly placed anus (HP:0001545)1.70401327
151Aplasia/Hypoplasia of the brainstem (HP:0007362)1.70312449
152Hypoplasia of the brainstem (HP:0002365)1.70312449
153Spastic tetraplegia (HP:0002510)1.70270733
154Neurofibrillary tangles (HP:0002185)1.69662082
155Protruding tongue (HP:0010808)1.68814501
156Exotropia (HP:0000577)1.68648274
157Incomplete penetrance (HP:0003829)1.67470531
158Abnormality of the corticospinal tract (HP:0002492)1.67333290

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK33.61331372
2MAP3K93.30244261
3MARK13.24781956
4MAP3K42.84325293
5MAP2K72.70997901
6CASK2.65983847
7FGFR22.44470339
8MINK12.41243505
9MAP4K22.40832855
10EPHA42.39051592
11PRKD32.28885679
12MAP3K122.18708876
13MAPK132.16702114
14KSR22.16498779
15KSR12.09760586
16PAK62.07768950
17EPHA32.01208388
18PRPF4B2.01193313
19TNIK2.00662914
20AKT31.89310121
21NTRK21.80562596
22MAP2K41.80286836
23BRAF1.73597847
24LATS21.65661255
25ADRBK21.61011343
26MAP3K61.60927939
27TRIM281.59266584
28SIK31.57064986
29NTRK11.53923834
30ARAF1.52524800
31UHMK11.45717565
32MAP2K61.38426199
33SGK4941.36796482
34SGK2231.36796482
35CSNK1G11.35150913
36SGK21.31294844
37PLK21.29372883
38GRK11.28001178
39BCR1.25760346
40GRK51.21653883
41MAP3K21.15138686
42FGFR31.14436187
43CDK51.13771826
44MST41.13190308
45DYRK21.11478785
46PASK1.09595506
47CDK191.06336496
48DYRK1A1.01390996
49CAMKK21.01278124
50DAPK20.99261636
51PAK30.97496505
52CSNK1A1L0.95928941
53RAF10.95856434
54STK38L0.95489709
55CAMK2A0.91203879
56ERBB30.88853507
57CSNK1G20.88151067
58PRKCG0.88057210
59CDK180.87905815
60PNCK0.87288356
61CDK140.86579632
62FRK0.86459136
63STK380.85924819
64DAPK10.85890384
65RET0.81857974
66MAP3K10.80973890
67ADRBK10.80426777
68MUSK0.79802235
69ERBB40.78217988
70CDK150.78195718
71SIK20.77655634
72WNK30.76348714
73PHKG10.76274704
74PHKG20.76274704
75PRKCE0.74375543
76PINK10.74270437
77OXSR10.74161662
78CAMKK10.73412156
79MAP3K130.72397115
80STK110.72012562
81CAMK2B0.71978049
82SGK30.70962950
83LATS10.70473769
84BMPR20.69975070
85INSRR0.65646162
86PRKAA10.63186208
87CDK11A0.63023624
88TYRO30.62991252
89MKNK20.60883399
90IRAK20.60471720
91CAMK10.59959811
92MARK20.59104266
93RPS6KA20.58387631
94CAMK1G0.58107596
95OBSCN0.55794137
96BRSK10.55600943
97SGK10.55283760
98CAMK2D0.54848911
99PRKCZ0.54735516
100PKN10.54655707
101MAP2K10.53658901
102STK30.52923727
103PRKG10.52922459
104CCNB10.52527866
105PRKACA0.52222192
106TRPM70.52177806
107TAOK10.51223607
108CSNK1G30.50877933
109HIPK20.50679342
110NLK0.48290447
111CSNK1A10.47425273
112FER0.47066126
113LIMK10.46764742
114CDK30.45768697
115STK390.44873514
116CDK80.44438370
117LMTK20.43141536
118PRKACB0.41835213
119GRK70.41499104
120CSNK1D0.41365615
121BMPR1B0.41189713
122RPS6KA30.39272500
123WNK40.38493151
124WNK10.37803039
125PRKAA20.37155068
126PRKCH0.36956752
127PLK30.36388331
128CDC42BPA0.35911086
129MAPK100.35720936
130CAMK2G0.35720412
131PRKCA0.34333147
132STK240.32513244
133BCKDK0.32469865
134MAP3K50.30029447
135CSNK1E0.29893616
136PRKACG0.29219697
137CAMK1D0.27008669
138YES10.25193755

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.00269167
2Synaptic vesicle cycle_Homo sapiens_hsa047213.40173467
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.77079893
4GABAergic synapse_Homo sapiens_hsa047272.70760470
5Morphine addiction_Homo sapiens_hsa050322.49164527
6Circadian entrainment_Homo sapiens_hsa047132.41101572
7Glutamatergic synapse_Homo sapiens_hsa047242.33926080
8Taste transduction_Homo sapiens_hsa047422.33650198
9Insulin secretion_Homo sapiens_hsa049112.30652248
10Long-term potentiation_Homo sapiens_hsa047202.30215840
11Amphetamine addiction_Homo sapiens_hsa050312.24204200
12Dopaminergic synapse_Homo sapiens_hsa047282.14703752
13* Butanoate metabolism_Homo sapiens_hsa006502.13117001
14Serotonergic synapse_Homo sapiens_hsa047262.09482228
15Olfactory transduction_Homo sapiens_hsa047402.09146059
16Collecting duct acid secretion_Homo sapiens_hsa049661.96167369
17Cocaine addiction_Homo sapiens_hsa050301.94106595
18Cholinergic synapse_Homo sapiens_hsa047251.84863058
19Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.78687096
20Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.76114889
21Long-term depression_Homo sapiens_hsa047301.71089008
22Vibrio cholerae infection_Homo sapiens_hsa051101.66350080
23Maturity onset diabetes of the young_Homo sapiens_hsa049501.60818763
24Salivary secretion_Homo sapiens_hsa049701.59540906
25Sulfur metabolism_Homo sapiens_hsa009201.58461209
26Aldosterone synthesis and secretion_Homo sapiens_hsa049251.47597127
27Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.45706761
28Circadian rhythm_Homo sapiens_hsa047101.43565939
29Folate biosynthesis_Homo sapiens_hsa007901.42839256
30Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.42563064
31Renin secretion_Homo sapiens_hsa049241.42110238
32Oxytocin signaling pathway_Homo sapiens_hsa049211.40460986
33Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.40453542
34* Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.38342055
35Gap junction_Homo sapiens_hsa045401.36878193
36Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.34633947
37Vitamin B6 metabolism_Homo sapiens_hsa007501.31749802
38GnRH signaling pathway_Homo sapiens_hsa049121.31345054
39Gastric acid secretion_Homo sapiens_hsa049711.27852844
40Type II diabetes mellitus_Homo sapiens_hsa049301.25789602
41Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.20547918
42Oocyte meiosis_Homo sapiens_hsa041141.19549950
43Calcium signaling pathway_Homo sapiens_hsa040201.18856104
44Propanoate metabolism_Homo sapiens_hsa006401.10981454
45cAMP signaling pathway_Homo sapiens_hsa040241.07694537
46Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.06504804
47Fatty acid elongation_Homo sapiens_hsa000621.03957901
48Cardiac muscle contraction_Homo sapiens_hsa042601.02461020
49Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.01571965
50* Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.01073028
51Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.99632678
52ErbB signaling pathway_Homo sapiens_hsa040120.96500925
53Phosphatidylinositol signaling system_Homo sapiens_hsa040700.96186898
54Estrogen signaling pathway_Homo sapiens_hsa049150.95436897
55Dorso-ventral axis formation_Homo sapiens_hsa043200.94239952
56Axon guidance_Homo sapiens_hsa043600.93853790
57Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.93571965
58cGMP-PKG signaling pathway_Homo sapiens_hsa040220.90407362
59Selenocompound metabolism_Homo sapiens_hsa004500.86030253
60Phototransduction_Homo sapiens_hsa047440.85188968
61Tryptophan metabolism_Homo sapiens_hsa003800.84906026
62* Peroxisome_Homo sapiens_hsa041460.84410796
63Glioma_Homo sapiens_hsa052140.84187052
64Alcoholism_Homo sapiens_hsa050340.83023076
65Melanogenesis_Homo sapiens_hsa049160.81419921
66Regulation of autophagy_Homo sapiens_hsa041400.81075578
67Vascular smooth muscle contraction_Homo sapiens_hsa042700.81037146
68Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.80151237
69Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.78725303
70Thyroid hormone synthesis_Homo sapiens_hsa049180.78295253
71Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.77129398
72Oxidative phosphorylation_Homo sapiens_hsa001900.76807012
73Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.76776313
74Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.76092736
75Primary bile acid biosynthesis_Homo sapiens_hsa001200.73979009
76Choline metabolism in cancer_Homo sapiens_hsa052310.73941189
77Dilated cardiomyopathy_Homo sapiens_hsa054140.73826800
78Nitrogen metabolism_Homo sapiens_hsa009100.72046238
79beta-Alanine metabolism_Homo sapiens_hsa004100.71271876
80MAPK signaling pathway_Homo sapiens_hsa040100.69928123
81ABC transporters_Homo sapiens_hsa020100.69786464
82Type I diabetes mellitus_Homo sapiens_hsa049400.69481152
83Pancreatic secretion_Homo sapiens_hsa049720.66456081
84Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.66345099
85Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.65762925
86Endometrial cancer_Homo sapiens_hsa052130.65724945
87Phospholipase D signaling pathway_Homo sapiens_hsa040720.64094998
88Ovarian steroidogenesis_Homo sapiens_hsa049130.63438455
89Ras signaling pathway_Homo sapiens_hsa040140.63148654
90Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.62783402
91Prolactin signaling pathway_Homo sapiens_hsa049170.62643901
92Mineral absorption_Homo sapiens_hsa049780.62283064
93Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.62240596
94Glucagon signaling pathway_Homo sapiens_hsa049220.60992106
95Steroid biosynthesis_Homo sapiens_hsa001000.60420410
96Protein export_Homo sapiens_hsa030600.60369265
97Basal transcription factors_Homo sapiens_hsa030220.59550612
98Renal cell carcinoma_Homo sapiens_hsa052110.58523088
99Sphingolipid metabolism_Homo sapiens_hsa006000.57343193
100Alzheimers disease_Homo sapiens_hsa050100.57174978
101Colorectal cancer_Homo sapiens_hsa052100.57111760
102Inositol phosphate metabolism_Homo sapiens_hsa005620.56295327
103Fatty acid metabolism_Homo sapiens_hsa012120.55016311
104Parkinsons disease_Homo sapiens_hsa050120.54337611
105Thyroid hormone signaling pathway_Homo sapiens_hsa049190.53173551
106Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.52845549
107Carbohydrate digestion and absorption_Homo sapiens_hsa049730.52519749
108Wnt signaling pathway_Homo sapiens_hsa043100.50419026
109Melanoma_Homo sapiens_hsa052180.50340464
110Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.49611484
111Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.48971757
112Neurotrophin signaling pathway_Homo sapiens_hsa047220.48533740
113mTOR signaling pathway_Homo sapiens_hsa041500.48185934
114Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.47823993
115Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.47300293
116Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.46320740
117Linoleic acid metabolism_Homo sapiens_hsa005910.46156433
118* Metabolic pathways_Homo sapiens_hsa011000.44688943
119SNARE interactions in vesicular transport_Homo sapiens_hsa041300.44554370
120Insulin signaling pathway_Homo sapiens_hsa049100.43860038
121Rheumatoid arthritis_Homo sapiens_hsa053230.43023206
122Huntingtons disease_Homo sapiens_hsa050160.41848060
123Rap1 signaling pathway_Homo sapiens_hsa040150.41057410
124Glycerophospholipid metabolism_Homo sapiens_hsa005640.38426844
125Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.37108583
126VEGF signaling pathway_Homo sapiens_hsa043700.36955162
127Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.35656447
128Phagosome_Homo sapiens_hsa041450.34711347
129Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.34231202
130Ether lipid metabolism_Homo sapiens_hsa005650.34094895
131AMPK signaling pathway_Homo sapiens_hsa041520.33701057
132Retinol metabolism_Homo sapiens_hsa008300.33193773
133Longevity regulating pathway - mammal_Homo sapiens_hsa042110.32315006
134Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.32300720
135Non-small cell lung cancer_Homo sapiens_hsa052230.31512773
136alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.31438851
137Hedgehog signaling pathway_Homo sapiens_hsa043400.30333106

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