

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 7.03623476 |
| 2 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 6.98929587 |
| 3 | DNA deamination (GO:0045006) | 6.95282110 |
| 4 | cytidine metabolic process (GO:0046087) | 6.08126073 |
| 5 | cytidine catabolic process (GO:0006216) | 6.08126073 |
| 6 | cytidine deamination (GO:0009972) | 6.08126073 |
| 7 | maturation of SSU-rRNA (GO:0030490) | 5.69444108 |
| 8 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.57773186 |
| 9 | chaperone-mediated protein transport (GO:0072321) | 5.39104721 |
| 10 | sequestering of actin monomers (GO:0042989) | 5.29110414 |
| 11 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.21219953 |
| 12 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 5.10423773 |
| 13 | viral transcription (GO:0019083) | 5.08388029 |
| 14 | translational termination (GO:0006415) | 4.98839094 |
| 15 | ribosomal small subunit biogenesis (GO:0042274) | 4.80623286 |
| 16 | ATP synthesis coupled proton transport (GO:0015986) | 4.55683067 |
| 17 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.55683067 |
| 18 | translational elongation (GO:0006414) | 4.53206383 |
| 19 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.40882792 |
| 20 | cotranslational protein targeting to membrane (GO:0006613) | 4.38015251 |
| 21 | protein targeting to ER (GO:0045047) | 4.34087364 |
| 22 | respiratory electron transport chain (GO:0022904) | 4.27350455 |
| 23 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.24995185 |
| 24 | electron transport chain (GO:0022900) | 4.22979690 |
| 25 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.15207394 |
| 26 | response to pheromone (GO:0019236) | 4.11868308 |
| 27 | regulation of mitochondrial translation (GO:0070129) | 4.05966699 |
| 28 | protein localization to endoplasmic reticulum (GO:0070972) | 4.01506568 |
| 29 | cellular protein complex disassembly (GO:0043624) | 3.98977889 |
| 30 | protein neddylation (GO:0045116) | 3.93869995 |
| 31 | dopamine transport (GO:0015872) | 3.90350256 |
| 32 | substrate-independent telencephalic tangential migration (GO:0021826) | 3.87435503 |
| 33 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 3.87435503 |
| 34 | viral life cycle (GO:0019058) | 3.84981329 |
| 35 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.56334209 |
| 36 | negative regulation by host of viral transcription (GO:0043922) | 3.54373394 |
| 37 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.49077878 |
| 38 | protein complex biogenesis (GO:0070271) | 3.44983061 |
| 39 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.44799591 |
| 40 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.41634479 |
| 41 | protein complex disassembly (GO:0043241) | 3.36919665 |
| 42 | ribosomal large subunit biogenesis (GO:0042273) | 3.34810031 |
| 43 | cell proliferation in forebrain (GO:0021846) | 3.34688188 |
| 44 | proteasome assembly (GO:0043248) | 3.30883333 |
| 45 | regulation of activation of Janus kinase activity (GO:0010533) | 3.26729393 |
| 46 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.21103826 |
| 47 | translational initiation (GO:0006413) | 3.20709440 |
| 48 | macromolecular complex disassembly (GO:0032984) | 3.19320429 |
| 49 | translation (GO:0006412) | 3.12312998 |
| 50 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.11570336 |
| 51 | platelet dense granule organization (GO:0060155) | 3.09340002 |
| 52 | protein-cofactor linkage (GO:0018065) | 3.08749914 |
| 53 | inner mitochondrial membrane organization (GO:0007007) | 3.07234183 |
| 54 | termination of RNA polymerase III transcription (GO:0006386) | 3.06052823 |
| 55 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.06052823 |
| 56 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.01346740 |
| 57 | regulation of dopamine uptake involved in synaptic transmission (GO:0051584) | 2.93816371 |
| 58 | regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) | 2.93816371 |
| 59 | maturation of 5.8S rRNA (GO:0000460) | 2.89550072 |
| 60 | protein targeting to membrane (GO:0006612) | 2.82681980 |
| 61 | positive regulation of respiratory burst (GO:0060267) | 2.82503091 |
| 62 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.78919750 |
| 63 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.78919750 |
| 64 | NADH dehydrogenase complex assembly (GO:0010257) | 2.78919750 |
| 65 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.78349315 |
| 66 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 2.76853417 |
| 67 | transmission of nerve impulse (GO:0019226) | 2.73737561 |
| 68 | chromatin remodeling at centromere (GO:0031055) | 2.70970162 |
| 69 | protein polyglutamylation (GO:0018095) | 2.69598317 |
| 70 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.69457503 |
| 71 | CENP-A containing nucleosome assembly (GO:0034080) | 2.69398078 |
| 72 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.65851843 |
| 73 | mRNA catabolic process (GO:0006402) | 2.65054705 |
| 74 | cellular component biogenesis (GO:0044085) | 2.63595870 |
| 75 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.63219000 |
| 76 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.62686546 |
| 77 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.62516692 |
| 78 | pyrimidine-containing compound catabolic process (GO:0072529) | 2.62172540 |
| 79 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.61849008 |
| 80 | microtubule depolymerization (GO:0007019) | 2.61727658 |
| 81 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.60254447 |
| 82 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.60254447 |
| 83 | hydrogen ion transmembrane transport (GO:1902600) | 2.58889258 |
| 84 | spliceosomal complex assembly (GO:0000245) | 2.57734820 |
| 85 | negative regulation of telomere maintenance (GO:0032205) | 2.57179350 |
| 86 | monocyte chemotaxis (GO:0002548) | 2.55982417 |
| 87 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.54845923 |
| 88 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.54845923 |
| 89 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.54845923 |
| 90 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.54051126 |
| 91 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.54051126 |
| 92 | modulation by host of viral transcription (GO:0043921) | 2.50968158 |
| 93 | modulation by host of symbiont transcription (GO:0052472) | 2.50968158 |
| 94 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.49392263 |
| 95 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.49392263 |
| 96 | negative regulation of mesenchymal cell apoptotic process (GO:2001054) | 2.48932384 |
| 97 | rRNA processing (GO:0006364) | 2.48469355 |
| 98 | pyrimidine nucleoside catabolic process (GO:0046135) | 2.48228168 |
| 99 | DNA replication checkpoint (GO:0000076) | 2.47274033 |
| 100 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.45066379 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 4.84443863 |
| 2 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.69764078 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.67137358 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.65242201 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.58484056 |
| 6 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.44694069 |
| 7 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.09501054 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.01724399 |
| 9 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.01022918 |
| 10 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.80298860 |
| 11 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.76765657 |
| 12 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.75030351 |
| 13 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.71102029 |
| 14 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.67298332 |
| 15 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.48693891 |
| 16 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.34810541 |
| 17 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.34787695 |
| 18 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.34679800 |
| 19 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.32405816 |
| 20 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.08659282 |
| 21 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.94544649 |
| 22 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.91542093 |
| 23 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.87771427 |
| 24 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.84238484 |
| 25 | VDR_22108803_ChIP-Seq_LS180_Human | 1.82258560 |
| 26 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.80976945 |
| 27 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.80951807 |
| 28 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.75827519 |
| 29 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.72768031 |
| 30 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.72737053 |
| 31 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.71949926 |
| 32 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.70755975 |
| 33 | EWS_26573619_Chip-Seq_HEK293_Human | 1.69358793 |
| 34 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.57750134 |
| 35 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.56093032 |
| 36 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.55801726 |
| 37 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.53399302 |
| 38 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.52968840 |
| 39 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.47922054 |
| 40 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.47765779 |
| 41 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.46011789 |
| 42 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.45017896 |
| 43 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.42754563 |
| 44 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.42180064 |
| 45 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.39704348 |
| 46 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.39011936 |
| 47 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.37834719 |
| 48 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.36364463 |
| 49 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.32004377 |
| 50 | FUS_26573619_Chip-Seq_HEK293_Human | 1.27365235 |
| 51 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.22966436 |
| 52 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.22735715 |
| 53 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.21518274 |
| 54 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.21390777 |
| 55 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.20220189 |
| 56 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.19535633 |
| 57 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.17635853 |
| 58 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.16375956 |
| 59 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.13734588 |
| 60 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.12062740 |
| 61 | AR_20517297_ChIP-Seq_VCAP_Human | 1.11750343 |
| 62 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.10997704 |
| 63 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.09108618 |
| 64 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.09041711 |
| 65 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.05591422 |
| 66 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.05434280 |
| 67 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.05111998 |
| 68 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.04960657 |
| 69 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.04127131 |
| 70 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.03521831 |
| 71 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.03465135 |
| 72 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.02443994 |
| 73 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.02443994 |
| 74 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.01650350 |
| 75 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.01197027 |
| 76 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.00946033 |
| 77 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.99986990 |
| 78 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.98517017 |
| 79 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.98189645 |
| 80 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.98189645 |
| 81 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.97039210 |
| 82 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.96731805 |
| 83 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.94182077 |
| 84 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.93327718 |
| 85 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.92505714 |
| 86 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.91289095 |
| 87 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.91249878 |
| 88 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.90309858 |
| 89 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.90251672 |
| 90 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.90059343 |
| 91 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.89210894 |
| 92 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.87856962 |
| 93 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.85963427 |
| 94 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.85607790 |
| 95 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.84423693 |
| 96 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.83514873 |
| 97 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.83361927 |
| 98 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.83194887 |
| 99 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.82453433 |
| 100 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.81136350 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 6.24410006 |
| 2 | MP0003880_abnormal_central_pattern | 5.40426137 |
| 3 | MP0002653_abnormal_ependyma_morphology | 4.33917080 |
| 4 | MP0003136_yellow_coat_color | 3.69375842 |
| 5 | MP0006292_abnormal_olfactory_placode | 3.31872803 |
| 6 | MP0005671_abnormal_response_to | 2.93338765 |
| 7 | MP0002102_abnormal_ear_morphology | 2.83244290 |
| 8 | MP0002234_abnormal_pharynx_morphology | 2.50807658 |
| 9 | MP0001293_anophthalmia | 2.26661695 |
| 10 | MP0003011_delayed_dark_adaptation | 2.16901408 |
| 11 | MP0006072_abnormal_retinal_apoptosis | 1.91443224 |
| 12 | MP0005084_abnormal_gallbladder_morpholo | 1.89397966 |
| 13 | MP0005645_abnormal_hypothalamus_physiol | 1.81679939 |
| 14 | MP0001529_abnormal_vocalization | 1.74662220 |
| 15 | MP0003693_abnormal_embryo_hatching | 1.69760150 |
| 16 | MP0003938_abnormal_ear_development | 1.69480151 |
| 17 | MP0004145_abnormal_muscle_electrophysio | 1.67252959 |
| 18 | MP0004147_increased_porphyrin_level | 1.65321237 |
| 19 | MP0002277_abnormal_respiratory_mucosa | 1.63310207 |
| 20 | MP0005174_abnormal_tail_pigmentation | 1.58019012 |
| 21 | MP0004142_abnormal_muscle_tone | 1.54401077 |
| 22 | MP0005253_abnormal_eye_physiology | 1.47756877 |
| 23 | MP0002095_abnormal_skin_pigmentation | 1.45621494 |
| 24 | MP0000026_abnormal_inner_ear | 1.44733023 |
| 25 | MP0009046_muscle_twitch | 1.40856910 |
| 26 | MP0003786_premature_aging | 1.39676506 |
| 27 | MP0003646_muscle_fatigue | 1.39108451 |
| 28 | MP0002638_abnormal_pupillary_reflex | 1.37788831 |
| 29 | MP0002876_abnormal_thyroid_physiology | 1.32908682 |
| 30 | MP0001905_abnormal_dopamine_level | 1.31955909 |
| 31 | MP0008058_abnormal_DNA_repair | 1.31456231 |
| 32 | MP0008877_abnormal_DNA_methylation | 1.24878034 |
| 33 | MP0001485_abnormal_pinna_reflex | 1.21904777 |
| 34 | MP0009785_altered_susceptibility_to | 1.18557528 |
| 35 | MP0003763_abnormal_thymus_physiology | 1.18048554 |
| 36 | MP0000631_abnormal_neuroendocrine_gland | 1.17496413 |
| 37 | MP0004742_abnormal_vestibular_system | 1.16597223 |
| 38 | MP0000049_abnormal_middle_ear | 1.15020234 |
| 39 | MP0005075_abnormal_melanosome_morpholog | 1.09742132 |
| 40 | MP0001764_abnormal_homeostasis | 1.09307731 |
| 41 | MP0008872_abnormal_physiological_respon | 1.09175932 |
| 42 | MP0005391_vision/eye_phenotype | 1.08699170 |
| 43 | MP0003878_abnormal_ear_physiology | 1.07482309 |
| 44 | MP0005377_hearing/vestibular/ear_phenot | 1.07482309 |
| 45 | MP0010094_abnormal_chromosome_stability | 1.05774687 |
| 46 | MP0000372_irregular_coat_pigmentation | 1.03752690 |
| 47 | MP0000778_abnormal_nervous_system | 1.03603084 |
| 48 | MP0008007_abnormal_cellular_replicative | 1.01545439 |
| 49 | MP0002736_abnormal_nociception_after | 0.99581594 |
| 50 | MP0001188_hyperpigmentation | 0.98534935 |
| 51 | MP0001873_stomach_inflammation | 0.94481541 |
| 52 | MP0002938_white_spotting | 0.93279017 |
| 53 | MP0003866_abnormal_defecation | 0.93166502 |
| 54 | MP0005551_abnormal_eye_electrophysiolog | 0.93065227 |
| 55 | MP0002160_abnormal_reproductive_system | 0.92746554 |
| 56 | MP0008789_abnormal_olfactory_epithelium | 0.92575407 |
| 57 | MP0002822_catalepsy | 0.89543039 |
| 58 | MP0003806_abnormal_nucleotide_metabolis | 0.88832925 |
| 59 | MP0003787_abnormal_imprinting | 0.87177329 |
| 60 | MP0002210_abnormal_sex_determination | 0.84534854 |
| 61 | MP0004957_abnormal_blastocyst_morpholog | 0.82484858 |
| 62 | MP0005389_reproductive_system_phenotype | 0.81061870 |
| 63 | MP0006276_abnormal_autonomic_nervous | 0.81052572 |
| 64 | MP0003111_abnormal_nucleus_morphology | 0.80920254 |
| 65 | MP0001800_abnormal_humoral_immune | 0.80725605 |
| 66 | MP0008995_early_reproductive_senescence | 0.80091409 |
| 67 | MP0001286_abnormal_eye_development | 0.79692156 |
| 68 | MP0002928_abnormal_bile_duct | 0.79296964 |
| 69 | MP0005195_abnormal_posterior_eye | 0.76942732 |
| 70 | MP0000685_abnormal_immune_system | 0.76836202 |
| 71 | MP0003937_abnormal_limbs/digits/tail_de | 0.76324564 |
| 72 | MP0001324_abnormal_eye_pigmentation | 0.75366122 |
| 73 | MP0001919_abnormal_reproductive_system | 0.72681323 |
| 74 | MP0000703_abnormal_thymus_morphology | 0.72459150 |
| 75 | MP0001984_abnormal_olfaction | 0.69438475 |
| 76 | MP0002751_abnormal_autonomic_nervous | 0.68063822 |
| 77 | MP0005387_immune_system_phenotype | 0.66957111 |
| 78 | MP0001790_abnormal_immune_system | 0.66957111 |
| 79 | MP0002697_abnormal_eye_size | 0.66953514 |
| 80 | MP0002272_abnormal_nervous_system | 0.66630985 |
| 81 | MP0001963_abnormal_hearing_physiology | 0.66480794 |
| 82 | MP0001879_abnormal_lymphatic_vessel | 0.66440641 |
| 83 | MP0009745_abnormal_behavioral_response | 0.64398527 |
| 84 | MP0002420_abnormal_adaptive_immunity | 0.63822772 |
| 85 | MP0002249_abnormal_larynx_morphology | 0.63735650 |
| 86 | MP0002752_abnormal_somatic_nervous | 0.63480353 |
| 87 | MP0003119_abnormal_digestive_system | 0.63069725 |
| 88 | MP0002398_abnormal_bone_marrow | 0.62278792 |
| 89 | MP0002233_abnormal_nose_morphology | 0.62082175 |
| 90 | MP0001929_abnormal_gametogenesis | 0.61786922 |
| 91 | MP0004885_abnormal_endolymph | 0.61720887 |
| 92 | MP0001968_abnormal_touch/_nociception | 0.60915081 |
| 93 | MP0001819_abnormal_immune_cell | 0.60473078 |
| 94 | MP0002837_dystrophic_cardiac_calcinosis | 0.60385866 |
| 95 | MP0008932_abnormal_embryonic_tissue | 0.60164801 |
| 96 | MP0006036_abnormal_mitochondrial_physio | 0.59934545 |
| 97 | MP0005646_abnormal_pituitary_gland | 0.58989083 |
| 98 | MP0002166_altered_tumor_susceptibility | 0.57438721 |
| 99 | MP0001119_abnormal_female_reproductive | 0.57425340 |
| 100 | MP0002723_abnormal_immune_serum | 0.57116142 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aplastic anemia (HP:0001915) | 4.70857971 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 4.53809594 |
| 3 | Reticulocytopenia (HP:0001896) | 4.37127635 |
| 4 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.11413785 |
| 5 | Mitochondrial inheritance (HP:0001427) | 4.10708701 |
| 6 | Increased hepatocellular lipid droplets (HP:0006565) | 4.07984568 |
| 7 | Lipid accumulation in hepatocytes (HP:0006561) | 3.85097525 |
| 8 | 11 pairs of ribs (HP:0000878) | 3.74860771 |
| 9 | Acute encephalopathy (HP:0006846) | 3.67154153 |
| 10 | Progressive macrocephaly (HP:0004481) | 3.59445040 |
| 11 | Fibular aplasia (HP:0002990) | 3.57575056 |
| 12 | Abnormal number of erythroid precursors (HP:0012131) | 3.46907992 |
| 13 | Increased CSF lactate (HP:0002490) | 3.44204054 |
| 14 | Renal Fanconi syndrome (HP:0001994) | 3.43910539 |
| 15 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.32360310 |
| 16 | Increased intramyocellular lipid droplets (HP:0012240) | 3.23005406 |
| 17 | Hepatocellular necrosis (HP:0001404) | 3.07320057 |
| 18 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 3.06237702 |
| 19 | Adactyly (HP:0009776) | 2.97167149 |
| 20 | Radial bowing (HP:0002986) | 2.96463646 |
| 21 | Hypoplastic pelvis (HP:0008839) | 2.95176478 |
| 22 | Macrocytic anemia (HP:0001972) | 2.92541132 |
| 23 | Congenital stationary night blindness (HP:0007642) | 2.91790186 |
| 24 | Cerebral edema (HP:0002181) | 2.90476518 |
| 25 | Synostosis involving the elbow (HP:0003938) | 2.85510449 |
| 26 | Humeroradial synostosis (HP:0003041) | 2.85510449 |
| 27 | Hepatic necrosis (HP:0002605) | 2.82719483 |
| 28 | Increased muscle lipid content (HP:0009058) | 2.80400848 |
| 29 | Absent thumb (HP:0009777) | 2.71179761 |
| 30 | Abnormality of the parietal bone (HP:0002696) | 2.71095466 |
| 31 | 3-Methylglutaconic aciduria (HP:0003535) | 2.69634252 |
| 32 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.65197485 |
| 33 | IgG deficiency (HP:0004315) | 2.60669811 |
| 34 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.60064254 |
| 35 | Respiratory difficulties (HP:0002880) | 2.57477294 |
| 36 | Exertional dyspnea (HP:0002875) | 2.51638793 |
| 37 | T lymphocytopenia (HP:0005403) | 2.50793361 |
| 38 | Hypoplasia of the radius (HP:0002984) | 2.42924068 |
| 39 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.42216982 |
| 40 | Pallor (HP:0000980) | 2.37684340 |
| 41 | Abnormal number of incisors (HP:0011064) | 2.33183944 |
| 42 | Molar tooth sign on MRI (HP:0002419) | 2.31391899 |
| 43 | Abnormality of midbrain morphology (HP:0002418) | 2.31391899 |
| 44 | Abnormality of T cell number (HP:0011839) | 2.31230142 |
| 45 | Pancreatic cysts (HP:0001737) | 2.28578068 |
| 46 | Aplasia/Hypoplasia of the fibula (HP:0006492) | 2.26955566 |
| 47 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.26776360 |
| 48 | Colon cancer (HP:0003003) | 2.23931006 |
| 49 | Pancytopenia (HP:0001876) | 2.23354829 |
| 50 | Methylmalonic acidemia (HP:0002912) | 2.19411321 |
| 51 | Abnormality of renal resorption (HP:0011038) | 2.17952783 |
| 52 | Oligodactyly (hands) (HP:0001180) | 2.17054737 |
| 53 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.15958940 |
| 54 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.14696497 |
| 55 | Leukodystrophy (HP:0002415) | 2.14634961 |
| 56 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 2.14240913 |
| 57 | Oral leukoplakia (HP:0002745) | 2.13911204 |
| 58 | Short tibia (HP:0005736) | 2.13178531 |
| 59 | Missing ribs (HP:0000921) | 2.12476063 |
| 60 | Partial duplication of thumb phalanx (HP:0009944) | 2.12386501 |
| 61 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.11436306 |
| 62 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.11436306 |
| 63 | Exercise intolerance (HP:0003546) | 2.10387866 |
| 64 | Methylmalonic aciduria (HP:0012120) | 2.09785433 |
| 65 | Sclerocornea (HP:0000647) | 2.07347067 |
| 66 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.05284455 |
| 67 | Optic disc pallor (HP:0000543) | 2.04730367 |
| 68 | Forearm undergrowth (HP:0009821) | 1.99773396 |
| 69 | Lactic acidosis (HP:0003128) | 1.98373044 |
| 70 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 1.96551214 |
| 71 | Partial duplication of the phalanx of hand (HP:0009999) | 1.96452862 |
| 72 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.94916726 |
| 73 | Abnormality of the pons (HP:0007361) | 1.93297957 |
| 74 | Hypoplasia of the pons (HP:0012110) | 1.91900944 |
| 75 | Increased serum lactate (HP:0002151) | 1.91630238 |
| 76 | Abnormality of urine glucose concentration (HP:0011016) | 1.91591946 |
| 77 | Glycosuria (HP:0003076) | 1.91591946 |
| 78 | Patellar aplasia (HP:0006443) | 1.90465446 |
| 79 | Abnormality of T cells (HP:0002843) | 1.88928642 |
| 80 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.88872541 |
| 81 | Duplication of thumb phalanx (HP:0009942) | 1.88228747 |
| 82 | Oligodactyly (HP:0012165) | 1.87753974 |
| 83 | Severe combined immunodeficiency (HP:0004430) | 1.85192794 |
| 84 | Bilateral microphthalmos (HP:0007633) | 1.83925127 |
| 85 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.82972902 |
| 86 | Dicarboxylic aciduria (HP:0003215) | 1.82972902 |
| 87 | Congenital, generalized hypertrichosis (HP:0004540) | 1.82238758 |
| 88 | Triphalangeal thumb (HP:0001199) | 1.82120151 |
| 89 | Hyperglycinemia (HP:0002154) | 1.81530095 |
| 90 | Short thumb (HP:0009778) | 1.81419165 |
| 91 | Respiratory failure (HP:0002878) | 1.80614168 |
| 92 | Chromsome breakage (HP:0040012) | 1.79080738 |
| 93 | Abnormality of the renal collecting system (HP:0004742) | 1.77594344 |
| 94 | Pancreatic fibrosis (HP:0100732) | 1.75321095 |
| 95 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.75171867 |
| 96 | Short 4th metacarpal (HP:0010044) | 1.75171867 |
| 97 | Hemivertebrae (HP:0002937) | 1.74346938 |
| 98 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.73522985 |
| 99 | Lethargy (HP:0001254) | 1.73039757 |
| 100 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.70934689 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TLK1 | 5.24039862 |
| 2 | TESK2 | 4.48849278 |
| 3 | VRK2 | 4.04478653 |
| 4 | TXK | 3.94420384 |
| 5 | VRK1 | 3.16738447 |
| 6 | BUB1 | 3.07232024 |
| 7 | KDR | 3.05520039 |
| 8 | ZAK | 2.77070769 |
| 9 | BCKDK | 2.60430835 |
| 10 | STK16 | 1.98417530 |
| 11 | TAF1 | 1.89622459 |
| 12 | MAP4K2 | 1.84797934 |
| 13 | DYRK2 | 1.75715458 |
| 14 | CDC7 | 1.73154635 |
| 15 | NUAK1 | 1.70748971 |
| 16 | GRK1 | 1.63188859 |
| 17 | CDK19 | 1.60081225 |
| 18 | BRSK2 | 1.52987648 |
| 19 | ADRBK2 | 1.46681285 |
| 20 | TNIK | 1.36764812 |
| 21 | WEE1 | 1.31713393 |
| 22 | SRPK1 | 1.23734221 |
| 23 | MAP4K1 | 1.23624993 |
| 24 | NME1 | 1.21423142 |
| 25 | LIMK1 | 1.17727678 |
| 26 | WNK4 | 1.17629334 |
| 27 | GRK7 | 1.16554495 |
| 28 | SYK | 1.11168909 |
| 29 | AURKA | 1.07520440 |
| 30 | WNK3 | 1.05302134 |
| 31 | ACVR1B | 1.04431092 |
| 32 | INSRR | 1.02965265 |
| 33 | ITK | 0.99722360 |
| 34 | TAOK3 | 0.99577201 |
| 35 | TESK1 | 0.99303836 |
| 36 | MAP3K12 | 0.96177912 |
| 37 | RPS6KA5 | 0.92519333 |
| 38 | MAP2K7 | 0.89928815 |
| 39 | CHEK2 | 0.87610061 |
| 40 | OXSR1 | 0.86132013 |
| 41 | MAPK15 | 0.83033400 |
| 42 | MAP3K4 | 0.82158542 |
| 43 | BMPR1B | 0.81869615 |
| 44 | PIK3CA | 0.79852961 |
| 45 | MAPK13 | 0.79669081 |
| 46 | MAPKAPK5 | 0.76981987 |
| 47 | PRKCQ | 0.74028704 |
| 48 | NTRK2 | 0.73146633 |
| 49 | NEK2 | 0.72688506 |
| 50 | EPHB2 | 0.72494543 |
| 51 | ADRBK1 | 0.70623554 |
| 52 | PLK1 | 0.70195551 |
| 53 | AURKB | 0.69125332 |
| 54 | PLK3 | 0.68198268 |
| 55 | DAPK3 | 0.65764990 |
| 56 | MUSK | 0.65488161 |
| 57 | PRKCG | 0.65137752 |
| 58 | CLK1 | 0.64310529 |
| 59 | CCNB1 | 0.61510095 |
| 60 | TIE1 | 0.61181884 |
| 61 | TYRO3 | 0.61076602 |
| 62 | UHMK1 | 0.60618773 |
| 63 | PLK4 | 0.56786218 |
| 64 | MKNK2 | 0.54437823 |
| 65 | LCK | 0.53428162 |
| 66 | CDK8 | 0.52607092 |
| 67 | ATR | 0.52185947 |
| 68 | NEK1 | 0.51282795 |
| 69 | PINK1 | 0.51208632 |
| 70 | PASK | 0.49567431 |
| 71 | CSNK2A1 | 0.47951767 |
| 72 | KIT | 0.46281311 |
| 73 | FES | 0.46261560 |
| 74 | MAP3K13 | 0.43434233 |
| 75 | PIM1 | 0.43082868 |
| 76 | MKNK1 | 0.43039091 |
| 77 | LYN | 0.41100453 |
| 78 | CAMKK2 | 0.40946001 |
| 79 | PHKG2 | 0.40488648 |
| 80 | PHKG1 | 0.40488648 |
| 81 | STK39 | 0.39671636 |
| 82 | CSF1R | 0.39265112 |
| 83 | CSNK2A2 | 0.39209369 |
| 84 | CDK11A | 0.38797550 |
| 85 | PKN1 | 0.38580507 |
| 86 | MST4 | 0.38054203 |
| 87 | DAPK1 | 0.37381478 |
| 88 | BRSK1 | 0.36966411 |
| 89 | MAP3K11 | 0.35596591 |
| 90 | PNCK | 0.35470737 |
| 91 | DYRK1A | 0.35316431 |
| 92 | IKBKE | 0.34899864 |
| 93 | EIF2AK2 | 0.33128444 |
| 94 | CDK15 | 0.32972443 |
| 95 | GRK5 | 0.32305381 |
| 96 | STK38L | 0.31267324 |
| 97 | PRKACA | 0.30728904 |
| 98 | DAPK2 | 0.30128662 |
| 99 | CDK18 | 0.29510559 |
| 100 | MARK1 | 0.29292923 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.73404446 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.19877905 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.87659372 |
| 4 | Proteasome_Homo sapiens_hsa03050 | 3.55879256 |
| 5 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.36556909 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.72399560 |
| 7 | Huntingtons disease_Homo sapiens_hsa05016 | 2.54834118 |
| 8 | Alzheimers disease_Homo sapiens_hsa05010 | 2.53568650 |
| 9 | Protein export_Homo sapiens_hsa03060 | 2.48164101 |
| 10 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.35186381 |
| 11 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 2.21564345 |
| 12 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.20827516 |
| 13 | Homologous recombination_Homo sapiens_hsa03440 | 2.10174811 |
| 14 | Mismatch repair_Homo sapiens_hsa03430 | 1.87988518 |
| 15 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.85623516 |
| 16 | DNA replication_Homo sapiens_hsa03030 | 1.82202455 |
| 17 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.72394787 |
| 18 | Spliceosome_Homo sapiens_hsa03040 | 1.70581946 |
| 19 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.68263814 |
| 20 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.64092462 |
| 21 | Phototransduction_Homo sapiens_hsa04744 | 1.57055663 |
| 22 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.52427877 |
| 23 | Allograft rejection_Homo sapiens_hsa05330 | 1.50960665 |
| 24 | Basal transcription factors_Homo sapiens_hsa03022 | 1.49044342 |
| 25 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.47684190 |
| 26 | RNA degradation_Homo sapiens_hsa03018 | 1.41105072 |
| 27 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.31121788 |
| 28 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.29455442 |
| 29 | Alcoholism_Homo sapiens_hsa05034 | 1.28844508 |
| 30 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.26844227 |
| 31 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.25862682 |
| 32 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.19544148 |
| 33 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.18537474 |
| 34 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.17469791 |
| 35 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.13642432 |
| 36 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.07883873 |
| 37 | Sulfur relay system_Homo sapiens_hsa04122 | 1.06291567 |
| 38 | Base excision repair_Homo sapiens_hsa03410 | 1.05191113 |
| 39 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.96571108 |
| 40 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.92061027 |
| 41 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.89146590 |
| 42 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.85509577 |
| 43 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.84393773 |
| 44 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.84340354 |
| 45 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.82437038 |
| 46 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.81819865 |
| 47 | Asthma_Homo sapiens_hsa05310 | 0.81317480 |
| 48 | Purine metabolism_Homo sapiens_hsa00230 | 0.81029840 |
| 49 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.75378267 |
| 50 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.75018098 |
| 51 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.71581108 |
| 52 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.70752577 |
| 53 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.69916744 |
| 54 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.67783479 |
| 55 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.66977529 |
| 56 | RNA transport_Homo sapiens_hsa03013 | 0.66559903 |
| 57 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.65535754 |
| 58 | Nicotine addiction_Homo sapiens_hsa05033 | 0.65285333 |
| 59 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.64032666 |
| 60 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.60784911 |
| 61 | Peroxisome_Homo sapiens_hsa04146 | 0.56960952 |
| 62 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.55843029 |
| 63 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.55649439 |
| 64 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.53552012 |
| 65 | Metabolic pathways_Homo sapiens_hsa01100 | 0.52349072 |
| 66 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.48883635 |
| 67 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.47156946 |
| 68 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.46203392 |
| 69 | Olfactory transduction_Homo sapiens_hsa04740 | 0.42212299 |
| 70 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.41822099 |
| 71 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.40587563 |
| 72 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.38053125 |
| 73 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.36562207 |
| 74 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.36021845 |
| 75 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.34901925 |
| 76 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.34782247 |
| 77 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.34160760 |
| 78 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.33337577 |
| 79 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.32853286 |
| 80 | Retinol metabolism_Homo sapiens_hsa00830 | 0.32852351 |
| 81 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.31556678 |
| 82 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.30943176 |
| 83 | Prion diseases_Homo sapiens_hsa05020 | 0.30619894 |
| 84 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.29504246 |
| 85 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.25941881 |
| 86 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.25675620 |
| 87 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.24722710 |
| 88 | Shigellosis_Homo sapiens_hsa05131 | 0.24647556 |
| 89 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.24281030 |
| 90 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.24207245 |
| 91 | Morphine addiction_Homo sapiens_hsa05032 | 0.23169827 |
| 92 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.22773332 |
| 93 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.22025745 |
| 94 | Viral myocarditis_Homo sapiens_hsa05416 | 0.21680285 |
| 95 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.21601440 |
| 96 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.21165403 |
| 97 | Cell cycle_Homo sapiens_hsa04110 | 0.20640952 |
| 98 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.18564595 |
| 99 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.16409322 |
| 100 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.15731138 |

