

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | synapsis (GO:0007129) | 6.49925332 |
| 2 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.95506247 |
| 3 | ATP synthesis coupled proton transport (GO:0015986) | 5.46217757 |
| 4 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.46217757 |
| 5 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 5.37905112 |
| 6 | cullin deneddylation (GO:0010388) | 5.12928322 |
| 7 | DNA deamination (GO:0045006) | 4.96972916 |
| 8 | sequestering of actin monomers (GO:0042989) | 4.90140450 |
| 9 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.81461867 |
| 10 | actin nucleation (GO:0045010) | 4.77451345 |
| 11 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.72664265 |
| 12 | protein deneddylation (GO:0000338) | 4.56988873 |
| 13 | protein neddylation (GO:0045116) | 4.47026816 |
| 14 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 4.45080248 |
| 15 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.42598840 |
| 16 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.41451235 |
| 17 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.37784319 |
| 18 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 4.33409727 |
| 19 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 4.33409727 |
| 20 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 4.33307733 |
| 21 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 4.33307733 |
| 22 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 4.33307733 |
| 23 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 4.30834752 |
| 24 | cytidine metabolic process (GO:0046087) | 4.17268551 |
| 25 | cytidine catabolic process (GO:0006216) | 4.17268551 |
| 26 | cytidine deamination (GO:0009972) | 4.17268551 |
| 27 | piRNA metabolic process (GO:0034587) | 4.15041358 |
| 28 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 4.14154685 |
| 29 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 4.14154685 |
| 30 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 4.12674143 |
| 31 | DNA double-strand break processing (GO:0000729) | 4.10603315 |
| 32 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 4.08792949 |
| 33 | fucose catabolic process (GO:0019317) | 3.99501075 |
| 34 | L-fucose metabolic process (GO:0042354) | 3.99501075 |
| 35 | L-fucose catabolic process (GO:0042355) | 3.99501075 |
| 36 | rRNA modification (GO:0000154) | 3.97993670 |
| 37 | negative regulation of ligase activity (GO:0051352) | 3.95372068 |
| 38 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.95372068 |
| 39 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.94506749 |
| 40 | mismatch repair (GO:0006298) | 3.92564410 |
| 41 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.88558838 |
| 42 | respiratory electron transport chain (GO:0022904) | 3.84557698 |
| 43 | electron transport chain (GO:0022900) | 3.80973701 |
| 44 | DNA ligation (GO:0006266) | 3.79105101 |
| 45 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.69613036 |
| 46 | rRNA methylation (GO:0031167) | 3.67903665 |
| 47 | proteasome assembly (GO:0043248) | 3.64966781 |
| 48 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.62521696 |
| 49 | resolution of meiotic recombination intermediates (GO:0000712) | 3.58993653 |
| 50 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.55844984 |
| 51 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.50414340 |
| 52 | ribosomal small subunit assembly (GO:0000028) | 3.48568780 |
| 53 | activated T cell proliferation (GO:0050798) | 3.45260570 |
| 54 | positive regulation of ligase activity (GO:0051351) | 3.44497074 |
| 55 | male meiosis I (GO:0007141) | 3.44086802 |
| 56 | chromosome organization involved in meiosis (GO:0070192) | 3.42874082 |
| 57 | response to pheromone (GO:0019236) | 3.41566922 |
| 58 | male meiosis (GO:0007140) | 3.40967404 |
| 59 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.34783986 |
| 60 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 3.34284120 |
| 61 | regulation of RIG-I signaling pathway (GO:0039535) | 3.33033729 |
| 62 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 3.31178301 |
| 63 | behavioral response to nicotine (GO:0035095) | 3.30651336 |
| 64 | DNA methylation involved in gamete generation (GO:0043046) | 3.30376570 |
| 65 | meiosis I (GO:0007127) | 3.30034692 |
| 66 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.29954281 |
| 67 | establishment of integrated proviral latency (GO:0075713) | 3.27128879 |
| 68 | pseudouridine synthesis (GO:0001522) | 3.25932669 |
| 69 | positive regulation of cell cycle arrest (GO:0071158) | 3.23160125 |
| 70 | negative regulation by host of viral transcription (GO:0043922) | 3.22064516 |
| 71 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 3.09833199 |
| 72 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.08667486 |
| 73 | regulation of cellular amine metabolic process (GO:0033238) | 3.06643520 |
| 74 | protein-cofactor linkage (GO:0018065) | 3.06106361 |
| 75 | negative regulation of cell cycle G1/S phase transition (GO:1902807) | 3.04343178 |
| 76 | negative regulation of G1/S transition of mitotic cell cycle (GO:2000134) | 3.04343178 |
| 77 | ATP biosynthetic process (GO:0006754) | 3.00896883 |
| 78 | mannosylation (GO:0097502) | 2.98040078 |
| 79 | inner mitochondrial membrane organization (GO:0007007) | 2.95640062 |
| 80 | ribonucleoprotein complex disassembly (GO:0032988) | 2.91897796 |
| 81 | regulation of ligase activity (GO:0051340) | 2.91266345 |
| 82 | cellular response to interferon-beta (GO:0035458) | 2.90960619 |
| 83 | protein complex biogenesis (GO:0070271) | 2.90563600 |
| 84 | negative T cell selection (GO:0043383) | 2.90193879 |
| 85 | aldehyde catabolic process (GO:0046185) | 2.86281012 |
| 86 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 2.84249408 |
| 87 | CENP-A containing nucleosome assembly (GO:0034080) | 2.83839805 |
| 88 | cytolysis (GO:0019835) | 2.82172931 |
| 89 | signal transduction in response to DNA damage (GO:0042770) | 2.81217793 |
| 90 | regulation of DNA endoreduplication (GO:0032875) | 2.80923954 |
| 91 | chaperone-mediated protein transport (GO:0072321) | 2.80640013 |
| 92 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.79411068 |
| 93 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.78456213 |
| 94 | hydrogen ion transmembrane transport (GO:1902600) | 2.75919643 |
| 95 | reciprocal DNA recombination (GO:0035825) | 2.71268998 |
| 96 | reciprocal meiotic recombination (GO:0007131) | 2.71268998 |
| 97 | regulation of cell cycle arrest (GO:0071156) | 2.70277505 |
| 98 | chromatin remodeling at centromere (GO:0031055) | 2.69573849 |
| 99 | intracellular protein transmembrane import (GO:0044743) | 2.68771063 |
| 100 | replication fork processing (GO:0031297) | 2.66846743 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.78975302 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.54616700 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.26969621 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.93875468 |
| 5 | IGF1R_20145208_ChIP-Seq_DFB_Human | 3.17484174 |
| 6 | VDR_22108803_ChIP-Seq_LS180_Human | 3.10132496 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.02792374 |
| 8 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.89300094 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.83475181 |
| 10 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.77448600 |
| 11 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.68492771 |
| 12 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.55850184 |
| 13 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.54032917 |
| 14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.38246602 |
| 15 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.30482363 |
| 16 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.27215065 |
| 17 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.17184050 |
| 18 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.14458760 |
| 19 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.12163210 |
| 20 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.00203252 |
| 21 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.97530740 |
| 22 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.93832316 |
| 23 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.93255339 |
| 24 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.89241400 |
| 25 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.83687375 |
| 26 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.76759196 |
| 27 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.76093723 |
| 28 | EWS_26573619_Chip-Seq_HEK293_Human | 1.73538799 |
| 29 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.66980849 |
| 30 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.66900127 |
| 31 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.58617807 |
| 32 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.56812423 |
| 33 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.53058449 |
| 34 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.42732496 |
| 35 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.41928891 |
| 36 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.41142452 |
| 37 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.40560643 |
| 38 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.37450757 |
| 39 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.36191916 |
| 40 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.30644146 |
| 41 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.30469366 |
| 42 | NCOR_22424771_ChIP-Seq_293T_Human | 1.30331912 |
| 43 | FUS_26573619_Chip-Seq_HEK293_Human | 1.30290992 |
| 44 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.30240902 |
| 45 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.30240902 |
| 46 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.28138833 |
| 47 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.27861084 |
| 48 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.27640710 |
| 49 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.27409452 |
| 50 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.26156722 |
| 51 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.25575790 |
| 52 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.23153759 |
| 53 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.22683542 |
| 54 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.22196524 |
| 55 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.21432874 |
| 56 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.21382398 |
| 57 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.17618664 |
| 58 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.17498163 |
| 59 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.17422423 |
| 60 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.17387340 |
| 61 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.16298253 |
| 62 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.14081177 |
| 63 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.12502685 |
| 64 | AR_20517297_ChIP-Seq_VCAP_Human | 1.11934503 |
| 65 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.11061922 |
| 66 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.11013845 |
| 67 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.09201079 |
| 68 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.08929022 |
| 69 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.08054757 |
| 70 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.05413067 |
| 71 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.04250443 |
| 72 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.03669686 |
| 73 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.03092399 |
| 74 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.02870783 |
| 75 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.02385094 |
| 76 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.02385094 |
| 77 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.01928716 |
| 78 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.01369534 |
| 79 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.00588096 |
| 80 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.98174151 |
| 81 | P300_19829295_ChIP-Seq_ESCs_Human | 0.97745582 |
| 82 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.97678537 |
| 83 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.96923134 |
| 84 | GATA3_26560356_Chip-Seq_TH2_Human | 0.96703433 |
| 85 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.95975445 |
| 86 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.95947463 |
| 87 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.95632088 |
| 88 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.95062881 |
| 89 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.95049828 |
| 90 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.94252297 |
| 91 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.94125625 |
| 92 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.93386875 |
| 93 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.92697742 |
| 94 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.91148580 |
| 95 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.90167850 |
| 96 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.89958234 |
| 97 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.89847395 |
| 98 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.89089396 |
| 99 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.88861850 |
| 100 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.88731106 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003136_yellow_coat_color | 5.44896581 |
| 2 | MP0008877_abnormal_DNA_methylation | 3.05766962 |
| 3 | MP0005671_abnormal_response_to | 2.58627907 |
| 4 | MP0003786_premature_aging | 2.45793825 |
| 5 | MP0002166_altered_tumor_susceptibility | 2.45746579 |
| 6 | MP0002736_abnormal_nociception_after | 2.43269541 |
| 7 | MP0006072_abnormal_retinal_apoptosis | 2.40869048 |
| 8 | MP0002102_abnormal_ear_morphology | 2.29832377 |
| 9 | MP0001968_abnormal_touch/_nociception | 2.28604202 |
| 10 | MP0008995_early_reproductive_senescence | 2.26068853 |
| 11 | MP0004147_increased_porphyrin_level | 2.25176644 |
| 12 | MP0005084_abnormal_gallbladder_morpholo | 2.17179600 |
| 13 | MP0003646_muscle_fatigue | 2.14320622 |
| 14 | MP0003806_abnormal_nucleotide_metabolis | 2.12555368 |
| 15 | MP0008007_abnormal_cellular_replicative | 2.10988891 |
| 16 | MP0002822_catalepsy | 2.10336241 |
| 17 | MP0002837_dystrophic_cardiac_calcinosis | 2.08142487 |
| 18 | MP0002006_tumorigenesis | 2.03971591 |
| 19 | MP0008058_abnormal_DNA_repair | 2.00667106 |
| 20 | MP0006036_abnormal_mitochondrial_physio | 1.76329928 |
| 21 | MP0010094_abnormal_chromosome_stability | 1.66506591 |
| 22 | MP0001529_abnormal_vocalization | 1.64909991 |
| 23 | MP0002938_white_spotting | 1.63755399 |
| 24 | MP0002163_abnormal_gland_morphology | 1.63141865 |
| 25 | MP0005075_abnormal_melanosome_morpholog | 1.56501275 |
| 26 | MP0005551_abnormal_eye_electrophysiolog | 1.55368450 |
| 27 | MP0009333_abnormal_splenocyte_physiolog | 1.54978741 |
| 28 | MP0002160_abnormal_reproductive_system | 1.52517995 |
| 29 | MP0005379_endocrine/exocrine_gland_phen | 1.50663640 |
| 30 | MP0005389_reproductive_system_phenotype | 1.49395010 |
| 31 | MP0002876_abnormal_thyroid_physiology | 1.47430055 |
| 32 | MP0010386_abnormal_urinary_bladder | 1.46766195 |
| 33 | MP0002210_abnormal_sex_determination | 1.42854341 |
| 34 | MP0001835_abnormal_antigen_presentation | 1.42807371 |
| 35 | MP0004381_abnormal_hair_follicle | 1.41999578 |
| 36 | MP0001346_abnormal_lacrimal_gland | 1.40856823 |
| 37 | MP0006292_abnormal_olfactory_placode | 1.38665096 |
| 38 | MP0003718_maternal_effect | 1.36768635 |
| 39 | MP0002009_preneoplasia | 1.36377947 |
| 40 | MP0002095_abnormal_skin_pigmentation | 1.32704961 |
| 41 | MP0001485_abnormal_pinna_reflex | 1.25756898 |
| 42 | MP0000372_irregular_coat_pigmentation | 1.23647919 |
| 43 | MP0004957_abnormal_blastocyst_morpholog | 1.22380706 |
| 44 | MP0000685_abnormal_immune_system | 1.22369286 |
| 45 | MP0005645_abnormal_hypothalamus_physiol | 1.22325171 |
| 46 | MP0008872_abnormal_physiological_respon | 1.22172772 |
| 47 | MP0001764_abnormal_homeostasis | 1.21155277 |
| 48 | MP0005253_abnormal_eye_physiology | 1.19884576 |
| 49 | MP0006035_abnormal_mitochondrial_morpho | 1.15613793 |
| 50 | MP0001929_abnormal_gametogenesis | 1.15436418 |
| 51 | MP0002638_abnormal_pupillary_reflex | 1.13372079 |
| 52 | MP0004145_abnormal_muscle_electrophysio | 1.13336806 |
| 53 | MP0001145_abnormal_male_reproductive | 1.13214098 |
| 54 | MP0000653_abnormal_sex_gland | 1.13200713 |
| 55 | MP0006082_CNS_inflammation | 1.11842096 |
| 56 | MP0001905_abnormal_dopamine_level | 1.11592326 |
| 57 | MP0003252_abnormal_bile_duct | 1.10981178 |
| 58 | MP0005646_abnormal_pituitary_gland | 1.08796615 |
| 59 | MP0001119_abnormal_female_reproductive | 1.06949810 |
| 60 | MP0000631_abnormal_neuroendocrine_gland | 1.06277958 |
| 61 | MP0003880_abnormal_central_pattern | 1.06141909 |
| 62 | MP0002138_abnormal_hepatobiliary_system | 1.05858836 |
| 63 | MP0004885_abnormal_endolymph | 1.04483840 |
| 64 | MP0002928_abnormal_bile_duct | 1.03411962 |
| 65 | MP0004142_abnormal_muscle_tone | 1.02022260 |
| 66 | MP0001919_abnormal_reproductive_system | 1.01080749 |
| 67 | MP0004215_abnormal_myocardial_fiber | 1.00293123 |
| 68 | MP0004043_abnormal_pH_regulation | 0.99605913 |
| 69 | MP0005167_abnormal_blood-brain_barrier | 0.99043925 |
| 70 | MP0002282_abnormal_trachea_morphology | 0.98858128 |
| 71 | MP0003698_abnormal_male_reproductive | 0.95327586 |
| 72 | MP0008932_abnormal_embryonic_tissue | 0.94859992 |
| 73 | MP0003763_abnormal_thymus_physiology | 0.94624828 |
| 74 | MP0003195_calcinosis | 0.94294377 |
| 75 | MP0004036_abnormal_muscle_relaxation | 0.93732864 |
| 76 | MP0003693_abnormal_embryo_hatching | 0.92869673 |
| 77 | MP0001800_abnormal_humoral_immune | 0.92558317 |
| 78 | MP0005503_abnormal_tendon_morphology | 0.87666731 |
| 79 | MP0002751_abnormal_autonomic_nervous | 0.86131683 |
| 80 | MP0002653_abnormal_ependyma_morphology | 0.85541414 |
| 81 | MP0005377_hearing/vestibular/ear_phenot | 0.82789815 |
| 82 | MP0003878_abnormal_ear_physiology | 0.82789815 |
| 83 | MP0001293_anophthalmia | 0.82344271 |
| 84 | MP0002272_abnormal_nervous_system | 0.80682006 |
| 85 | MP0002723_abnormal_immune_serum | 0.77092694 |
| 86 | MP0009745_abnormal_behavioral_response | 0.76287513 |
| 87 | MP0001661_extended_life_span | 0.73862167 |
| 88 | MP0009697_abnormal_copulation | 0.73425028 |
| 89 | MP0008789_abnormal_olfactory_epithelium | 0.73032102 |
| 90 | MP0005670_abnormal_white_adipose | 0.72381042 |
| 91 | MP0002420_abnormal_adaptive_immunity | 0.71912170 |
| 92 | MP0005647_abnormal_sex_gland | 0.71894144 |
| 93 | MP0006276_abnormal_autonomic_nervous | 0.68447561 |
| 94 | MP0001819_abnormal_immune_cell | 0.66688733 |
| 95 | MP0001963_abnormal_hearing_physiology | 0.65140633 |
| 96 | MP0009046_muscle_twitch | 0.64881891 |
| 97 | MP0005000_abnormal_immune_tolerance | 0.64359795 |
| 98 | MP0009379_abnormal_foot_pigmentation | 0.63676421 |
| 99 | MP0005195_abnormal_posterior_eye | 0.63372024 |
| 100 | MP0001984_abnormal_olfaction | 0.62751422 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aplastic anemia (HP:0001915) | 4.66681130 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.00117418 |
| 3 | Increased hepatocellular lipid droplets (HP:0006565) | 3.93690515 |
| 4 | Lipid accumulation in hepatocytes (HP:0006561) | 3.71823397 |
| 5 | Acute necrotizing encephalopathy (HP:0006965) | 3.70944600 |
| 6 | Increased CSF lactate (HP:0002490) | 3.67265647 |
| 7 | Hepatocellular necrosis (HP:0001404) | 3.54286643 |
| 8 | Renal Fanconi syndrome (HP:0001994) | 3.53928306 |
| 9 | Acute encephalopathy (HP:0006846) | 3.52451257 |
| 10 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.45338731 |
| 11 | Congenital, generalized hypertrichosis (HP:0004540) | 3.41151344 |
| 12 | Autoimmune thrombocytopenia (HP:0001973) | 3.38902354 |
| 13 | Hepatic necrosis (HP:0002605) | 3.36491066 |
| 14 | Congenital stationary night blindness (HP:0007642) | 3.18421247 |
| 15 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.16533936 |
| 16 | Progressive macrocephaly (HP:0004481) | 3.10936885 |
| 17 | Increased IgM level (HP:0003496) | 3.06563764 |
| 18 | Autoimmune hemolytic anemia (HP:0001890) | 3.06470741 |
| 19 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.03209539 |
| 20 | Pancreatic cysts (HP:0001737) | 2.93760038 |
| 21 | Increased intramyocellular lipid droplets (HP:0012240) | 2.90902410 |
| 22 | Severe combined immunodeficiency (HP:0004430) | 2.89652093 |
| 23 | Abnormal number of erythroid precursors (HP:0012131) | 2.89456531 |
| 24 | Supernumerary spleens (HP:0009799) | 2.84572997 |
| 25 | Amyotrophic lateral sclerosis (HP:0007354) | 2.80927897 |
| 26 | Oligodactyly (hands) (HP:0001180) | 2.74760637 |
| 27 | Cerebral edema (HP:0002181) | 2.74041019 |
| 28 | Abnormality of the labia minora (HP:0012880) | 2.69949840 |
| 29 | Absent thumb (HP:0009777) | 2.59219735 |
| 30 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.58931664 |
| 31 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.52726347 |
| 32 | Pancreatic fibrosis (HP:0100732) | 2.52172773 |
| 33 | Meckel diverticulum (HP:0002245) | 2.50276956 |
| 34 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.49541619 |
| 35 | 3-Methylglutaconic aciduria (HP:0003535) | 2.47421729 |
| 36 | True hermaphroditism (HP:0010459) | 2.46753795 |
| 37 | Increased muscle lipid content (HP:0009058) | 2.46016695 |
| 38 | Clubbing of toes (HP:0100760) | 2.45707982 |
| 39 | Exertional dyspnea (HP:0002875) | 2.43088291 |
| 40 | Combined immunodeficiency (HP:0005387) | 2.36453391 |
| 41 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.35574687 |
| 42 | Abnormality of the ileum (HP:0001549) | 2.33823857 |
| 43 | Abnormality of eosinophils (HP:0001879) | 2.33650270 |
| 44 | Increased serum lactate (HP:0002151) | 2.31698453 |
| 45 | Eosinophilia (HP:0001880) | 2.31612936 |
| 46 | Thyroiditis (HP:0100646) | 2.29139994 |
| 47 | Pancytopenia (HP:0001876) | 2.28818613 |
| 48 | Hyperglycinuria (HP:0003108) | 2.28443711 |
| 49 | Abnormality of chromosome stability (HP:0003220) | 2.28359150 |
| 50 | Abnormality of T cells (HP:0002843) | 2.27272221 |
| 51 | Abnormality of T cell number (HP:0011839) | 2.25683867 |
| 52 | Abnormality of renal resorption (HP:0011038) | 2.24676296 |
| 53 | Abolished electroretinogram (ERG) (HP:0000550) | 2.23565136 |
| 54 | Optic disc pallor (HP:0000543) | 2.23001818 |
| 55 | Generalized aminoaciduria (HP:0002909) | 2.21942789 |
| 56 | Nephronophthisis (HP:0000090) | 2.21209593 |
| 57 | Pendular nystagmus (HP:0012043) | 2.20826977 |
| 58 | Abnormal lung lobation (HP:0002101) | 2.17265504 |
| 59 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.16100820 |
| 60 | Panhypogammaglobulinemia (HP:0003139) | 2.14846388 |
| 61 | Hyperglycinemia (HP:0002154) | 2.14229618 |
| 62 | Lactic acidosis (HP:0003128) | 2.14048284 |
| 63 | Abnormality of T cell physiology (HP:0011840) | 2.10863350 |
| 64 | Abnormality of serum amino acid levels (HP:0003112) | 2.07898739 |
| 65 | IgG deficiency (HP:0004315) | 2.07189451 |
| 66 | Glycosuria (HP:0003076) | 2.07147899 |
| 67 | Abnormality of urine glucose concentration (HP:0011016) | 2.07147899 |
| 68 | Abnormality of alanine metabolism (HP:0010916) | 2.03903557 |
| 69 | Hyperalaninemia (HP:0003348) | 2.03903557 |
| 70 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.03903557 |
| 71 | Medial flaring of the eyebrow (HP:0010747) | 2.03588347 |
| 72 | Delayed CNS myelination (HP:0002188) | 2.01851456 |
| 73 | Respiratory difficulties (HP:0002880) | 2.01410716 |
| 74 | Respiratory failure (HP:0002878) | 2.00020302 |
| 75 | Duodenal stenosis (HP:0100867) | 1.99474174 |
| 76 | Small intestinal stenosis (HP:0012848) | 1.99474174 |
| 77 | Abnormality of the renal medulla (HP:0100957) | 1.98790046 |
| 78 | Colon cancer (HP:0003003) | 1.98277823 |
| 79 | CNS demyelination (HP:0007305) | 1.98201468 |
| 80 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.96357704 |
| 81 | Abnormality of glycine metabolism (HP:0010895) | 1.96357704 |
| 82 | Hypoglycemic seizures (HP:0002173) | 1.95623001 |
| 83 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.94760516 |
| 84 | Abnormality of the preputium (HP:0100587) | 1.92529097 |
| 85 | Abnormal drinking behavior (HP:0030082) | 1.92468073 |
| 86 | Polydipsia (HP:0001959) | 1.92468073 |
| 87 | Cystic liver disease (HP:0006706) | 1.91206155 |
| 88 | Oral leukoplakia (HP:0002745) | 1.91056617 |
| 89 | Lethargy (HP:0001254) | 1.89657667 |
| 90 | Molar tooth sign on MRI (HP:0002419) | 1.89573945 |
| 91 | Abnormality of midbrain morphology (HP:0002418) | 1.89573945 |
| 92 | Encephalitis (HP:0002383) | 1.82437338 |
| 93 | Decreased central vision (HP:0007663) | 1.82042641 |
| 94 | Limb hypertonia (HP:0002509) | 1.80977647 |
| 95 | Reticulocytopenia (HP:0001896) | 1.79974029 |
| 96 | Oligodactyly (HP:0012165) | 1.79900535 |
| 97 | Gonadotropin excess (HP:0000837) | 1.79425920 |
| 98 | Abnormality of the renal cortex (HP:0011035) | 1.76652064 |
| 99 | Chromsome breakage (HP:0040012) | 1.76386855 |
| 100 | Abnormality of the duodenum (HP:0002246) | 1.76223676 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BUB1 | 3.78646048 |
| 2 | STK16 | 3.53166023 |
| 3 | VRK2 | 3.40305142 |
| 4 | EIF2AK3 | 3.32664514 |
| 5 | MAP3K12 | 2.97548006 |
| 6 | KDR | 2.96576868 |
| 7 | EPHA3 | 2.44720975 |
| 8 | EIF2AK1 | 2.43763045 |
| 9 | SRPK1 | 2.30391752 |
| 10 | BCR | 2.20902099 |
| 11 | TESK2 | 2.15605188 |
| 12 | ZAK | 1.94959865 |
| 13 | NUAK1 | 1.93646439 |
| 14 | OXSR1 | 1.92781973 |
| 15 | VRK1 | 1.86709034 |
| 16 | ADRBK2 | 1.82511151 |
| 17 | TXK | 1.79409921 |
| 18 | DYRK2 | 1.79091002 |
| 19 | TSSK6 | 1.75349335 |
| 20 | BRSK2 | 1.71214183 |
| 21 | TLK1 | 1.66448455 |
| 22 | PASK | 1.55525319 |
| 23 | MKNK1 | 1.47362984 |
| 24 | BRSK1 | 1.43136319 |
| 25 | GRK1 | 1.39314898 |
| 26 | MAP4K2 | 1.38305354 |
| 27 | EPHB1 | 1.35686888 |
| 28 | TAOK3 | 1.31517662 |
| 29 | TNIK | 1.30120472 |
| 30 | STK39 | 1.29594676 |
| 31 | BCKDK | 1.26074337 |
| 32 | CSNK1G3 | 1.26015017 |
| 33 | PLK3 | 1.25664513 |
| 34 | MKNK2 | 1.22426547 |
| 35 | NEK1 | 1.22058776 |
| 36 | ACVR1B | 1.15239293 |
| 37 | MST4 | 1.15028659 |
| 38 | EIF2AK2 | 1.13394745 |
| 39 | RPS6KA5 | 1.03067314 |
| 40 | PLK2 | 1.02810201 |
| 41 | WNK3 | 0.98348724 |
| 42 | CSNK1G2 | 0.97471851 |
| 43 | FRK | 0.97425945 |
| 44 | CSNK1A1L | 0.96792137 |
| 45 | CDC7 | 0.96023703 |
| 46 | DAPK1 | 0.95087734 |
| 47 | TGFBR2 | 0.94837266 |
| 48 | WNK4 | 0.90095924 |
| 49 | MAPK15 | 0.87153824 |
| 50 | PAK4 | 0.85301479 |
| 51 | MAP4K1 | 0.84560700 |
| 52 | CSNK1G1 | 0.83645360 |
| 53 | FGFR2 | 0.80787670 |
| 54 | STK38L | 0.80155573 |
| 55 | NLK | 0.79186092 |
| 56 | NME1 | 0.78564741 |
| 57 | PINK1 | 0.76910667 |
| 58 | LIMK1 | 0.74927430 |
| 59 | PDK2 | 0.74559125 |
| 60 | MAP3K11 | 0.73854940 |
| 61 | RPS6KA4 | 0.71102792 |
| 62 | DAPK2 | 0.68553778 |
| 63 | MAPKAPK5 | 0.66756744 |
| 64 | MARK3 | 0.62626701 |
| 65 | EPHA4 | 0.62297222 |
| 66 | WEE1 | 0.61446110 |
| 67 | PNCK | 0.58812225 |
| 68 | GRK5 | 0.56327718 |
| 69 | AURKB | 0.55271401 |
| 70 | ITK | 0.53386895 |
| 71 | ATR | 0.53198205 |
| 72 | PRKCQ | 0.52487951 |
| 73 | INSRR | 0.51166237 |
| 74 | CDK19 | 0.50464669 |
| 75 | MAP3K5 | 0.50344074 |
| 76 | DYRK3 | 0.50097685 |
| 77 | PLK1 | 0.48493200 |
| 78 | MAPKAPK3 | 0.45661328 |
| 79 | FES | 0.43545835 |
| 80 | CSNK2A1 | 0.42289722 |
| 81 | PRKCI | 0.42134833 |
| 82 | PRKCG | 0.41874476 |
| 83 | GRK7 | 0.41468421 |
| 84 | TRIM28 | 0.40141114 |
| 85 | BTK | 0.39196516 |
| 86 | GRK6 | 0.39099404 |
| 87 | CSNK2A2 | 0.39073060 |
| 88 | IKBKB | 0.38377776 |
| 89 | SYK | 0.36699583 |
| 90 | MINK1 | 0.35964573 |
| 91 | PKN1 | 0.35779354 |
| 92 | LYN | 0.34446124 |
| 93 | MAPKAPK2 | 0.32614768 |
| 94 | AURKA | 0.30398132 |
| 95 | KIT | 0.30044602 |
| 96 | TEC | 0.29126792 |
| 97 | DYRK1B | 0.28299354 |
| 98 | ATM | 0.28254636 |
| 99 | IRAK4 | 0.27562061 |
| 100 | PRKCE | 0.26875252 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.99740581 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.90945614 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.45240841 |
| 4 | Protein export_Homo sapiens_hsa03060 | 2.89834037 |
| 5 | Ribosome_Homo sapiens_hsa03010 | 2.88386026 |
| 6 | Mismatch repair_Homo sapiens_hsa03430 | 2.73266956 |
| 7 | DNA replication_Homo sapiens_hsa03030 | 2.45641812 |
| 8 | Phototransduction_Homo sapiens_hsa04744 | 2.39192580 |
| 9 | Huntingtons disease_Homo sapiens_hsa05016 | 2.34078651 |
| 10 | Alzheimers disease_Homo sapiens_hsa05010 | 2.27191691 |
| 11 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.20180508 |
| 12 | Homologous recombination_Homo sapiens_hsa03440 | 2.02823706 |
| 13 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.99837888 |
| 14 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.95402012 |
| 15 | RNA polymerase_Homo sapiens_hsa03020 | 1.91347501 |
| 16 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.90214933 |
| 17 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.88959517 |
| 18 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.77256422 |
| 19 | Spliceosome_Homo sapiens_hsa03040 | 1.67595352 |
| 20 | RNA degradation_Homo sapiens_hsa03018 | 1.63843129 |
| 21 | RNA transport_Homo sapiens_hsa03013 | 1.49412214 |
| 22 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.47368032 |
| 23 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.46063217 |
| 24 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.44281806 |
| 25 | Allograft rejection_Homo sapiens_hsa05330 | 1.43185618 |
| 26 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.42043616 |
| 27 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.41996868 |
| 28 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.40317708 |
| 29 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.36723475 |
| 30 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.31907067 |
| 31 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.28355595 |
| 32 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.26643083 |
| 33 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.23980593 |
| 34 | Basal transcription factors_Homo sapiens_hsa03022 | 1.23855252 |
| 35 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.17262637 |
| 36 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.15619934 |
| 37 | Asthma_Homo sapiens_hsa05310 | 1.14193641 |
| 38 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.02314887 |
| 39 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.01631192 |
| 40 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.00669705 |
| 41 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.97378805 |
| 42 | Purine metabolism_Homo sapiens_hsa00230 | 0.91734622 |
| 43 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.90390166 |
| 44 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.90341752 |
| 45 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.89444399 |
| 46 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.87420503 |
| 47 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.86994257 |
| 48 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.80984518 |
| 49 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.78210729 |
| 50 | Peroxisome_Homo sapiens_hsa04146 | 0.76631708 |
| 51 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.73156095 |
| 52 | Base excision repair_Homo sapiens_hsa03410 | 0.71261358 |
| 53 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.71091703 |
| 54 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.69054456 |
| 55 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.68928935 |
| 56 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.66232764 |
| 57 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.64874445 |
| 58 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.64604068 |
| 59 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.60895093 |
| 60 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.60841849 |
| 61 | Cell cycle_Homo sapiens_hsa04110 | 0.60289693 |
| 62 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.60086676 |
| 63 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.59860516 |
| 64 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.58099811 |
| 65 | Sulfur relay system_Homo sapiens_hsa04122 | 0.55164044 |
| 66 | Metabolic pathways_Homo sapiens_hsa01100 | 0.54327933 |
| 67 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.54156485 |
| 68 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.53094849 |
| 69 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.52746333 |
| 70 | Taste transduction_Homo sapiens_hsa04742 | 0.50869520 |
| 71 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.47981504 |
| 72 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.45939320 |
| 73 | Shigellosis_Homo sapiens_hsa05131 | 0.45863074 |
| 74 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.45203168 |
| 75 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.44620131 |
| 76 | Olfactory transduction_Homo sapiens_hsa04740 | 0.41679415 |
| 77 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.41534382 |
| 78 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.40564642 |
| 79 | Viral myocarditis_Homo sapiens_hsa05416 | 0.39649196 |
| 80 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.38093727 |
| 81 | Mineral absorption_Homo sapiens_hsa04978 | 0.37438585 |
| 82 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.35761189 |
| 83 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.35335847 |
| 84 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.34875115 |
| 85 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.34172805 |
| 86 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.34172778 |
| 87 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.33204436 |
| 88 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.32085352 |
| 89 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.31333845 |
| 90 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.31090941 |
| 91 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.30776724 |
| 92 | Retinol metabolism_Homo sapiens_hsa00830 | 0.29322153 |
| 93 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.27731118 |
| 94 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.26776997 |
| 95 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.23337869 |
| 96 | Measles_Homo sapiens_hsa05162 | 0.22739124 |
| 97 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.21363357 |
| 98 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.19811668 |
| 99 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.19344974 |
| 100 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.18436472 |

