

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | cytidine deamination (GO:0009972) | 9.91044034 |
| 2 | cytidine metabolic process (GO:0046087) | 9.91044034 |
| 3 | cytidine catabolic process (GO:0006216) | 9.91044034 |
| 4 | DNA deamination (GO:0045006) | 8.85280525 |
| 5 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 8.82428260 |
| 6 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 8.00208457 |
| 7 | actin nucleation (GO:0045010) | 7.16545756 |
| 8 | sequestering of actin monomers (GO:0042989) | 6.92631843 |
| 9 | negative regulation of stress fiber assembly (GO:0051497) | 5.92639365 |
| 10 | T cell migration (GO:0072678) | 5.60529800 |
| 11 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.45427313 |
| 12 | negative regulation of T cell apoptotic process (GO:0070233) | 5.27459170 |
| 13 | negative regulation by host of viral transcription (GO:0043922) | 5.05958398 |
| 14 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 4.96175207 |
| 15 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 4.92949239 |
| 16 | macrophage chemotaxis (GO:0048246) | 4.87584839 |
| 17 | cytolysis (GO:0019835) | 4.80199102 |
| 18 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.58092665 |
| 19 | positive thymic T cell selection (GO:0045059) | 4.57359040 |
| 20 | negative regulation of monooxygenase activity (GO:0032769) | 4.57354561 |
| 21 | negative regulation of actin filament bundle assembly (GO:0032232) | 4.56812276 |
| 22 | pyrimidine nucleoside catabolic process (GO:0046135) | 4.53804254 |
| 23 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 4.53661600 |
| 24 | positive T cell selection (GO:0043368) | 4.52140488 |
| 25 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 4.38456256 |
| 26 | regulation of natural killer cell mediated immunity (GO:0002715) | 4.38456256 |
| 27 | eosinophil chemotaxis (GO:0048245) | 4.34221901 |
| 28 | cellular response to interleukin-15 (GO:0071350) | 4.27264825 |
| 29 | negative regulation of oxidoreductase activity (GO:0051354) | 4.14647156 |
| 30 | negative regulation of viral genome replication (GO:0045071) | 4.14634420 |
| 31 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.13112260 |
| 32 | positive regulation of lamellipodium assembly (GO:0010592) | 4.10848712 |
| 33 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.97315964 |
| 34 | eosinophil migration (GO:0072677) | 3.93990687 |
| 35 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.89658608 |
| 36 | positive regulation of cell killing (GO:0031343) | 3.88416572 |
| 37 | positive regulation of translational initiation (GO:0045948) | 3.87757401 |
| 38 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 3.77701348 |
| 39 | regulation of activation of Janus kinase activity (GO:0010533) | 3.72636715 |
| 40 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.70381631 |
| 41 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.64143613 |
| 42 | positive regulation of monocyte chemotaxis (GO:0090026) | 3.63124082 |
| 43 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 3.58121860 |
| 44 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.51942490 |
| 45 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.47835666 |
| 46 | regulation of lymphocyte chemotaxis (GO:1901623) | 3.46399670 |
| 47 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.44551079 |
| 48 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.43970563 |
| 49 | regulation of cell killing (GO:0031341) | 3.39762025 |
| 50 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.39186909 |
| 51 | ATP synthesis coupled proton transport (GO:0015986) | 3.39186909 |
| 52 | regulation of T cell chemotaxis (GO:0010819) | 3.38594247 |
| 53 | positive regulation of T cell chemotaxis (GO:0010820) | 3.38594247 |
| 54 | positive regulation of interleukin-8 secretion (GO:2000484) | 3.35489005 |
| 55 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 3.28530354 |
| 56 | positive regulation of lamellipodium organization (GO:1902745) | 3.28333621 |
| 57 | lymphocyte migration (GO:0072676) | 3.28048347 |
| 58 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.26819327 |
| 59 | cellular defense response (GO:0006968) | 3.26806636 |
| 60 | T cell receptor signaling pathway (GO:0050852) | 3.23654253 |
| 61 | thymic T cell selection (GO:0045061) | 3.23443424 |
| 62 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 3.23071260 |
| 63 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.22947294 |
| 64 | regulation of T cell apoptotic process (GO:0070232) | 3.22802586 |
| 65 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.21851612 |
| 66 | negative T cell selection (GO:0043383) | 3.21380430 |
| 67 | metallo-sulfur cluster assembly (GO:0031163) | 3.20844887 |
| 68 | iron-sulfur cluster assembly (GO:0016226) | 3.20844887 |
| 69 | negative regulation of nitric-oxide synthase activity (GO:0051001) | 3.16443427 |
| 70 | regulation of viral genome replication (GO:0045069) | 3.11792064 |
| 71 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.11203524 |
| 72 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.11203524 |
| 73 | positive regulation of B cell differentiation (GO:0045579) | 3.07413515 |
| 74 | respiratory electron transport chain (GO:0022904) | 3.04850963 |
| 75 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.04417493 |
| 76 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.04417493 |
| 77 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.04417493 |
| 78 | response to interleukin-15 (GO:0070672) | 3.04095014 |
| 79 | protein neddylation (GO:0045116) | 3.03558158 |
| 80 | regulation of vitamin D biosynthetic process (GO:0060556) | 3.02123320 |
| 81 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.01609324 |
| 82 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.00434154 |
| 83 | lymphocyte chemotaxis (GO:0048247) | 3.00073746 |
| 84 | positive regulation of lymphocyte migration (GO:2000403) | 2.99716916 |
| 85 | T cell costimulation (GO:0031295) | 2.98356190 |
| 86 | electron transport chain (GO:0022900) | 2.95846359 |
| 87 | regulation of T cell tolerance induction (GO:0002664) | 2.95473352 |
| 88 | regulation of chronic inflammatory response (GO:0002676) | 2.95144328 |
| 89 | lymphocyte costimulation (GO:0031294) | 2.94849658 |
| 90 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.91526840 |
| 91 | positive regulation of tolerance induction (GO:0002645) | 2.90218709 |
| 92 | dendritic cell chemotaxis (GO:0002407) | 2.88130909 |
| 93 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.86937025 |
| 94 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.86937025 |
| 95 | regulation of regulatory T cell differentiation (GO:0045589) | 2.85586567 |
| 96 | positive regulation of gamma-delta T cell activation (GO:0046645) | 2.84825498 |
| 97 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 2.83067036 |
| 98 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.82520204 |
| 99 | T cell selection (GO:0045058) | 2.82490108 |
| 100 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 10.2085720 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.64153191 |
| 2 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 4.66496090 |
| 3 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.52290133 |
| 4 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 4.45733171 |
| 5 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.92710557 |
| 6 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.52340766 |
| 7 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.32063886 |
| 8 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.06508786 |
| 9 | MYB_26560356_Chip-Seq_TH2_Human | 3.04143683 |
| 10 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.91569343 |
| 11 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.91382786 |
| 12 | VDR_22108803_ChIP-Seq_LS180_Human | 2.70266358 |
| 13 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.61706555 |
| 14 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.49818246 |
| 15 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.40725499 |
| 16 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.23133919 |
| 17 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.15808530 |
| 18 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.11291852 |
| 19 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.09446739 |
| 20 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.05470086 |
| 21 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.01111963 |
| 22 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.00491527 |
| 23 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.90235321 |
| 24 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.81368236 |
| 25 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.79401320 |
| 26 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.76621197 |
| 27 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.76531821 |
| 28 | MYB_26560356_Chip-Seq_TH1_Human | 1.76164912 |
| 29 | UTX_26944678_Chip-Seq_JUKART_Human | 1.75203854 |
| 30 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.72019599 |
| 31 | GATA3_26560356_Chip-Seq_TH2_Human | 1.70238715 |
| 32 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.68184566 |
| 33 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.67861617 |
| 34 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.62951852 |
| 35 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.57239602 |
| 36 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.53325144 |
| 37 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.49715932 |
| 38 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.48445374 |
| 39 | MAF_26560356_Chip-Seq_TH1_Human | 1.47616293 |
| 40 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.43975074 |
| 41 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.43338823 |
| 42 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.42881303 |
| 43 | MAF_26560356_Chip-Seq_TH2_Human | 1.42224993 |
| 44 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.41663445 |
| 45 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.37719921 |
| 46 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.36190185 |
| 47 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.35497195 |
| 48 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.33797010 |
| 49 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.31996841 |
| 50 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.31928387 |
| 51 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.31526859 |
| 52 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.28467071 |
| 53 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.20105413 |
| 54 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.19301594 |
| 55 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.18440207 |
| 56 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.11964166 |
| 57 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.11964037 |
| 58 | AR_20517297_ChIP-Seq_VCAP_Human | 1.10439422 |
| 59 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.09190612 |
| 60 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.08807179 |
| 61 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.07490841 |
| 62 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.07062432 |
| 63 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.06767208 |
| 64 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.05446814 |
| 65 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.04588410 |
| 66 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.04244576 |
| 67 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.03701848 |
| 68 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.02386832 |
| 69 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.02230902 |
| 70 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.01213642 |
| 71 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.00660669 |
| 72 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.00196749 |
| 73 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.96096114 |
| 74 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.95383652 |
| 75 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.95383652 |
| 76 | P300_27268052_Chip-Seq_Bcells_Human | 0.94613072 |
| 77 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.94561121 |
| 78 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.94249924 |
| 79 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.93966021 |
| 80 | SA1_27219007_Chip-Seq_Bcells_Human | 0.93654918 |
| 81 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.93534652 |
| 82 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.93143202 |
| 83 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.93009055 |
| 84 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.92597429 |
| 85 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.92251931 |
| 86 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.92236160 |
| 87 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.92236160 |
| 88 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.91284046 |
| 89 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.90945615 |
| 90 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.90352217 |
| 91 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.90219423 |
| 92 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.87426252 |
| 93 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.86541067 |
| 94 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.85577962 |
| 95 | GATA3_26560356_Chip-Seq_TH1_Human | 0.85470301 |
| 96 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.84182025 |
| 97 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.83290711 |
| 98 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.82693084 |
| 99 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.82154237 |
| 100 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.79524320 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 6.80528697 |
| 2 | MP0009333_abnormal_splenocyte_physiolog | 3.92501642 |
| 3 | MP0003763_abnormal_thymus_physiology | 3.38904485 |
| 4 | MP0006082_CNS_inflammation | 3.25091693 |
| 5 | MP0009785_altered_susceptibility_to | 3.22994575 |
| 6 | MP0001835_abnormal_antigen_presentation | 3.09816567 |
| 7 | MP0004147_increased_porphyrin_level | 2.87669566 |
| 8 | MP0002166_altered_tumor_susceptibility | 2.85393416 |
| 9 | MP0005000_abnormal_immune_tolerance | 2.58970145 |
| 10 | MP0005025_abnormal_response_to | 2.32479317 |
| 11 | MP0002420_abnormal_adaptive_immunity | 2.31433397 |
| 12 | MP0001800_abnormal_humoral_immune | 2.29696716 |
| 13 | MP0001819_abnormal_immune_cell | 2.20547892 |
| 14 | MP0002723_abnormal_immune_serum | 2.18122230 |
| 15 | MP0002006_tumorigenesis | 2.07504124 |
| 16 | MP0001873_stomach_inflammation | 2.06442875 |
| 17 | MP0005464_abnormal_platelet_physiology | 2.03512143 |
| 18 | MP0002148_abnormal_hypersensitivity_rea | 2.02246318 |
| 19 | MP0000685_abnormal_immune_system | 1.99849227 |
| 20 | MP0003448_altered_tumor_morphology | 1.91076761 |
| 21 | MP0005387_immune_system_phenotype | 1.90189545 |
| 22 | MP0001790_abnormal_immune_system | 1.90189545 |
| 23 | MP0002452_abnormal_antigen_presenting | 1.83137099 |
| 24 | MP0002933_joint_inflammation | 1.78863081 |
| 25 | MP0006054_spinal_hemorrhage | 1.76419273 |
| 26 | MP0002398_abnormal_bone_marrow | 1.68784112 |
| 27 | MP0002405_respiratory_system_inflammati | 1.65231849 |
| 28 | MP0004145_abnormal_muscle_electrophysio | 1.63501143 |
| 29 | MP0000716_abnormal_immune_system | 1.60483334 |
| 30 | MP0001905_abnormal_dopamine_level | 1.53278255 |
| 31 | MP0001845_abnormal_inflammatory_respons | 1.50850371 |
| 32 | MP0003866_abnormal_defecation | 1.50398540 |
| 33 | MP0003283_abnormal_digestive_organ | 1.50062086 |
| 34 | MP0001485_abnormal_pinna_reflex | 1.49469696 |
| 35 | MP0010386_abnormal_urinary_bladder | 1.48656876 |
| 36 | MP0002722_abnormal_immune_system | 1.47076008 |
| 37 | MP0010155_abnormal_intestine_physiology | 1.46343845 |
| 38 | MP0002138_abnormal_hepatobiliary_system | 1.42838513 |
| 39 | MP0000689_abnormal_spleen_morphology | 1.41936151 |
| 40 | MP0002419_abnormal_innate_immunity | 1.39985815 |
| 41 | MP0000703_abnormal_thymus_morphology | 1.36141517 |
| 42 | MP0003786_premature_aging | 1.35163020 |
| 43 | MP0000372_irregular_coat_pigmentation | 1.31020968 |
| 44 | MP0003075_altered_response_to | 1.30906085 |
| 45 | MP0002102_abnormal_ear_morphology | 1.28562904 |
| 46 | MP0002429_abnormal_blood_cell | 1.25745950 |
| 47 | MP0002876_abnormal_thyroid_physiology | 1.23797488 |
| 48 | MP0002837_dystrophic_cardiac_calcinosis | 1.20337194 |
| 49 | MP0003436_decreased_susceptibility_to | 1.19816375 |
| 50 | MP0001919_abnormal_reproductive_system | 1.19688092 |
| 51 | MP0005645_abnormal_hypothalamus_physiol | 1.19432335 |
| 52 | MP0002736_abnormal_nociception_after | 1.18685322 |
| 53 | MP0001968_abnormal_touch/_nociception | 1.18208313 |
| 54 | MP0001765_abnormal_ion_homeostasis | 1.18191930 |
| 55 | MP0001188_hyperpigmentation | 1.17110971 |
| 56 | MP0005551_abnormal_eye_electrophysiolog | 1.15438679 |
| 57 | MP0005166_decreased_susceptibility_to | 1.14597564 |
| 58 | MP0005083_abnormal_biliary_tract | 1.13493852 |
| 59 | MP0001661_extended_life_span | 1.12912049 |
| 60 | MP0008469_abnormal_protein_level | 1.09551058 |
| 61 | MP0009763_increased_sensitivity_to | 1.09429241 |
| 62 | MP0005084_abnormal_gallbladder_morpholo | 1.08911647 |
| 63 | MP0008872_abnormal_physiological_respon | 1.06581818 |
| 64 | MP0003045_fibrosis | 1.06414412 |
| 65 | MP0004742_abnormal_vestibular_system | 1.04655512 |
| 66 | MP0003137_abnormal_impulse_conducting | 1.03466308 |
| 67 | MP0001542_abnormal_bone_strength | 1.01581288 |
| 68 | MP0009379_abnormal_foot_pigmentation | 1.00093428 |
| 69 | MP0001853_heart_inflammation | 0.97813826 |
| 70 | MP0005636_abnormal_mineral_homeostasis | 0.96893963 |
| 71 | MP0005646_abnormal_pituitary_gland | 0.92811618 |
| 72 | MP0003806_abnormal_nucleotide_metabolis | 0.92034537 |
| 73 | MP0001727_abnormal_embryo_implantation | 0.91216359 |
| 74 | MP0001666_abnormal_nutrient_absorption | 0.90647717 |
| 75 | MP0003567_abnormal_fetal_cardiomyocyte | 0.88583125 |
| 76 | MP0005410_abnormal_fertilization | 0.88268268 |
| 77 | MP0004947_skin_inflammation | 0.87446694 |
| 78 | MP0000858_altered_metastatic_potential | 0.87371369 |
| 79 | MP0000604_amyloidosis | 0.87276473 |
| 80 | MP0008877_abnormal_DNA_methylation | 0.83411166 |
| 81 | MP0002693_abnormal_pancreas_physiology | 0.81576835 |
| 82 | MP0005389_reproductive_system_phenotype | 0.78931944 |
| 83 | MP0002019_abnormal_tumor_incidence | 0.78629080 |
| 84 | MP0003252_abnormal_bile_duct | 0.77268049 |
| 85 | MP0009643_abnormal_urine_homeostasis | 0.75274872 |
| 86 | MP0000639_abnormal_adrenal_gland | 0.74715842 |
| 87 | MP0005451_abnormal_body_composition | 0.74004852 |
| 88 | MP0009764_decreased_sensitivity_to | 0.71940872 |
| 89 | MP0001533_abnormal_skeleton_physiology | 0.71522634 |
| 90 | MP0008995_early_reproductive_senescence | 0.70750404 |
| 91 | MP0003646_muscle_fatigue | 0.69463038 |
| 92 | MP0005075_abnormal_melanosome_morpholog | 0.67694634 |
| 93 | MP0005319_abnormal_enzyme/_coenzyme | 0.67677457 |
| 94 | MP0005377_hearing/vestibular/ear_phenot | 0.63767722 |
| 95 | MP0003878_abnormal_ear_physiology | 0.63767722 |
| 96 | MP0006072_abnormal_retinal_apoptosis | 0.63424962 |
| 97 | MP0001764_abnormal_homeostasis | 0.63253356 |
| 98 | MP0001119_abnormal_female_reproductive | 0.63029923 |
| 99 | MP0000343_altered_response_to | 0.62514298 |
| 100 | MP0004134_abnormal_chest_morphology | 0.62126277 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of B cell number (HP:0010975) | 5.85059888 |
| 2 | B lymphocytopenia (HP:0010976) | 5.84661848 |
| 3 | T lymphocytopenia (HP:0005403) | 5.68129400 |
| 4 | Increased IgM level (HP:0003496) | 5.43931466 |
| 5 | Abnormality of T cell number (HP:0011839) | 5.34305779 |
| 6 | IgG deficiency (HP:0004315) | 5.33261332 |
| 7 | Hypoproteinemia (HP:0003075) | 5.05447284 |
| 8 | Aplastic anemia (HP:0001915) | 4.63001864 |
| 9 | Autoimmune hemolytic anemia (HP:0001890) | 4.46471404 |
| 10 | Severe combined immunodeficiency (HP:0004430) | 4.39911418 |
| 11 | Thyroiditis (HP:0100646) | 4.18808195 |
| 12 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.83164515 |
| 13 | Encephalitis (HP:0002383) | 3.60148169 |
| 14 | Combined immunodeficiency (HP:0005387) | 3.58203218 |
| 15 | Abnormality of eosinophils (HP:0001879) | 3.57371254 |
| 16 | Acute hepatic failure (HP:0006554) | 3.44139976 |
| 17 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.41565739 |
| 18 | Abolished electroretinogram (ERG) (HP:0000550) | 3.32742341 |
| 19 | Abnormality of the prostate (HP:0008775) | 3.26481688 |
| 20 | Acute necrotizing encephalopathy (HP:0006965) | 3.22599073 |
| 21 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.20281532 |
| 22 | Recurrent cutaneous fungal infections (HP:0011370) | 3.20281532 |
| 23 | Stomatitis (HP:0010280) | 3.19340704 |
| 24 | Hypoplasia of the thymus (HP:0000778) | 3.18938571 |
| 25 | Abnormality of macrophages (HP:0004311) | 3.16652891 |
| 26 | Abnormality of T cells (HP:0002843) | 3.10797568 |
| 27 | Gastrointestinal infarctions (HP:0005244) | 3.00024269 |
| 28 | Mitochondrial inheritance (HP:0001427) | 2.99379260 |
| 29 | Chronic diarrhea (HP:0002028) | 2.98033526 |
| 30 | Severe visual impairment (HP:0001141) | 2.96246381 |
| 31 | Cerebral edema (HP:0002181) | 2.94757790 |
| 32 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.93558610 |
| 33 | Decreased central vision (HP:0007663) | 2.93266397 |
| 34 | Abnormal albumin level (HP:0012116) | 2.89529232 |
| 35 | Hypoalbuminemia (HP:0003073) | 2.89529232 |
| 36 | Eosinophilia (HP:0001880) | 2.86989743 |
| 37 | Leukocytosis (HP:0001974) | 2.74136466 |
| 38 | Lymphopenia (HP:0001888) | 2.72141777 |
| 39 | Progressive macrocephaly (HP:0004481) | 2.70955973 |
| 40 | Meningitis (HP:0001287) | 2.69138526 |
| 41 | Hemiplegia (HP:0002301) | 2.68645136 |
| 42 | Autoimmune thrombocytopenia (HP:0001973) | 2.67034403 |
| 43 | Renal Fanconi syndrome (HP:0001994) | 2.66734501 |
| 44 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.66314183 |
| 45 | Hypergammaglobulinemia (HP:0010702) | 2.65870774 |
| 46 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.60420061 |
| 47 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.60420061 |
| 48 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.53835365 |
| 49 | Tetraplegia (HP:0002445) | 2.52443044 |
| 50 | Obstructive lung disease (HP:0006536) | 2.48694674 |
| 51 | Chronic obstructive pulmonary disease (HP:0006510) | 2.48694674 |
| 52 | Radial bowing (HP:0002986) | 2.46956601 |
| 53 | Pendular nystagmus (HP:0012043) | 2.41950219 |
| 54 | Increased corneal curvature (HP:0100692) | 2.41167102 |
| 55 | Keratoconus (HP:0000563) | 2.41167102 |
| 56 | Acute encephalopathy (HP:0006846) | 2.40548032 |
| 57 | Pancytopenia (HP:0001876) | 2.39681230 |
| 58 | Mediastinal lymphadenopathy (HP:0100721) | 2.39349437 |
| 59 | Recurrent bronchitis (HP:0002837) | 2.35863634 |
| 60 | Abnormality of binocular vision (HP:0011514) | 2.26072671 |
| 61 | Diplopia (HP:0000651) | 2.26072671 |
| 62 | Recurrent fungal infections (HP:0002841) | 2.25333293 |
| 63 | Lymphoma (HP:0002665) | 2.19768635 |
| 64 | Agammaglobulinemia (HP:0004432) | 2.18999638 |
| 65 | Increased intramyocellular lipid droplets (HP:0012240) | 2.18801156 |
| 66 | Generalized aminoaciduria (HP:0002909) | 2.18262793 |
| 67 | Ureteral stenosis (HP:0000071) | 2.13601133 |
| 68 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.12595021 |
| 69 | Increased CSF lactate (HP:0002490) | 2.12406843 |
| 70 | Recurrent viral infections (HP:0004429) | 2.10166391 |
| 71 | Chest pain (HP:0100749) | 2.08791703 |
| 72 | Type I transferrin isoform profile (HP:0003642) | 2.05867559 |
| 73 | Granulocytopenia (HP:0001913) | 2.05384616 |
| 74 | Congenital stationary night blindness (HP:0007642) | 1.98887027 |
| 75 | Amyotrophic lateral sclerosis (HP:0007354) | 1.93952968 |
| 76 | Attenuation of retinal blood vessels (HP:0007843) | 1.92576536 |
| 77 | Ureteral obstruction (HP:0006000) | 1.90457275 |
| 78 | Gangrene (HP:0100758) | 1.90078145 |
| 79 | Reduced antithrombin III activity (HP:0001976) | 1.89762158 |
| 80 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.83913889 |
| 81 | Joint swelling (HP:0001386) | 1.83345405 |
| 82 | Increased hepatocellular lipid droplets (HP:0006565) | 1.82879207 |
| 83 | Pancreatic fibrosis (HP:0100732) | 1.82608713 |
| 84 | Erythema (HP:0010783) | 1.82198553 |
| 85 | Spontaneous hematomas (HP:0007420) | 1.81205559 |
| 86 | Cellular immunodeficiency (HP:0005374) | 1.80458533 |
| 87 | Pigmentary retinal degeneration (HP:0001146) | 1.79885602 |
| 88 | 3-Methylglutaconic aciduria (HP:0003535) | 1.78870596 |
| 89 | Lethargy (HP:0001254) | 1.78545548 |
| 90 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.74116060 |
| 91 | Hepatocellular necrosis (HP:0001404) | 1.73930072 |
| 92 | Increased muscle lipid content (HP:0009058) | 1.73584190 |
| 93 | Recurrent abscess formation (HP:0002722) | 1.72801362 |
| 94 | Pustule (HP:0200039) | 1.69829813 |
| 95 | Pancreatitis (HP:0001733) | 1.69749230 |
| 96 | Abnormality of male internal genitalia (HP:0000022) | 1.68072534 |
| 97 | Orthostatic hypotension (HP:0001278) | 1.63976979 |
| 98 | True hermaphroditism (HP:0010459) | 1.62990483 |
| 99 | Hemoptysis (HP:0002105) | 1.62988273 |
| 100 | Pulmonary embolism (HP:0002204) | 1.62578805 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BCKDK | 6.99354588 |
| 2 | KDR | 6.59062192 |
| 3 | TESK2 | 5.89473525 |
| 4 | TESK1 | 3.02378102 |
| 5 | TXK | 2.90360009 |
| 6 | MAP3K12 | 2.57554867 |
| 7 | GRK6 | 2.55683570 |
| 8 | ITK | 2.39859565 |
| 9 | MAP4K1 | 2.27350164 |
| 10 | LIMK1 | 2.26063504 |
| 11 | TNK2 | 1.91630278 |
| 12 | TEC | 1.74047172 |
| 13 | MAP3K11 | 1.72702442 |
| 14 | TAOK3 | 1.64222152 |
| 15 | MYLK | 1.59166511 |
| 16 | GRK7 | 1.52805112 |
| 17 | ADRBK2 | 1.52595756 |
| 18 | MAP2K7 | 1.48753475 |
| 19 | VRK2 | 1.37467438 |
| 20 | GRK1 | 1.36535606 |
| 21 | BTK | 1.36151031 |
| 22 | SYK | 1.32805854 |
| 23 | RPS6KA4 | 1.23902678 |
| 24 | FES | 1.17353258 |
| 25 | PRKCQ | 1.09109318 |
| 26 | MAP4K2 | 1.08732943 |
| 27 | CSNK1G3 | 1.03967858 |
| 28 | CSK | 1.02484769 |
| 29 | BUB1 | 1.02043321 |
| 30 | TBK1 | 1.00225185 |
| 31 | CSF1R | 0.96759592 |
| 32 | LCK | 0.96567998 |
| 33 | MATK | 0.96296767 |
| 34 | VRK1 | 0.89230869 |
| 35 | TIE1 | 0.82691624 |
| 36 | NUAK1 | 0.80267626 |
| 37 | LYN | 0.77367307 |
| 38 | CSNK1A1L | 0.74584777 |
| 39 | AURKA | 0.74503042 |
| 40 | STK16 | 0.72217783 |
| 41 | FRK | 0.68608362 |
| 42 | CSNK1G1 | 0.67176018 |
| 43 | PRKCH | 0.62763047 |
| 44 | PAK1 | 0.62359970 |
| 45 | PAK4 | 0.61189504 |
| 46 | INSRR | 0.59840226 |
| 47 | PTK2B | 0.59312646 |
| 48 | DAPK1 | 0.58897760 |
| 49 | MAP3K1 | 0.58041677 |
| 50 | ILK | 0.57529818 |
| 51 | RIPK4 | 0.56958569 |
| 52 | IKBKE | 0.56509575 |
| 53 | CSNK1G2 | 0.55995403 |
| 54 | MAPKAPK3 | 0.52086440 |
| 55 | ROCK1 | 0.48961852 |
| 56 | RPS6KA5 | 0.48724850 |
| 57 | FYN | 0.48606056 |
| 58 | PIK3CG | 0.48488868 |
| 59 | IKBKB | 0.46371420 |
| 60 | OBSCN | 0.45939876 |
| 61 | EPHB1 | 0.45898512 |
| 62 | BMPR2 | 0.45727209 |
| 63 | MAPK13 | 0.43614993 |
| 64 | SCYL2 | 0.41624160 |
| 65 | NTRK1 | 0.40421196 |
| 66 | PRKCA | 0.39560061 |
| 67 | JAK3 | 0.37466850 |
| 68 | ZAP70 | 0.37116143 |
| 69 | PINK1 | 0.34963624 |
| 70 | INSR | 0.34049351 |
| 71 | GRK5 | 0.33394449 |
| 72 | BRSK1 | 0.32210389 |
| 73 | MAPKAPK2 | 0.31560058 |
| 74 | PLK2 | 0.31134641 |
| 75 | IGF1R | 0.31077797 |
| 76 | TLK1 | 0.30980629 |
| 77 | PRKACA | 0.30612636 |
| 78 | WNK3 | 0.30111380 |
| 79 | MAP3K5 | 0.29816478 |
| 80 | DAPK3 | 0.29736123 |
| 81 | ERBB2 | 0.27606761 |
| 82 | BLK | 0.27346340 |
| 83 | PIK3CA | 0.27294564 |
| 84 | MUSK | 0.26981558 |
| 85 | PRKCD | 0.25372664 |
| 86 | MAPK11 | 0.25095638 |
| 87 | CSNK2A1 | 0.24432388 |
| 88 | ABL1 | 0.24304595 |
| 89 | JAK2 | 0.24206188 |
| 90 | CSNK1A1 | 0.23309329 |
| 91 | MELK | 0.23209690 |
| 92 | NME1 | 0.22768538 |
| 93 | CLK1 | 0.22087965 |
| 94 | KIT | 0.22083441 |
| 95 | ATR | 0.21916503 |
| 96 | TAOK2 | 0.21519664 |
| 97 | TAOK1 | 0.20858443 |
| 98 | CDK8 | 0.20857615 |
| 99 | BMPR1B | 0.20381873 |
| 100 | TRPM7 | 0.19233222 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 5.86514845 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 5.03848851 |
| 3 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.30381954 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.18182397 |
| 5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.17556556 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 3.11508223 |
| 7 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.75458959 |
| 8 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.68118509 |
| 9 | Parkinsons disease_Homo sapiens_hsa05012 | 2.62924071 |
| 10 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.53496847 |
| 11 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 2.48370235 |
| 12 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.39609857 |
| 13 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.26798150 |
| 14 | RNA polymerase_Homo sapiens_hsa03020 | 2.09256688 |
| 15 | Alzheimers disease_Homo sapiens_hsa05010 | 1.99852949 |
| 16 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.77600299 |
| 17 | Protein export_Homo sapiens_hsa03060 | 1.72289250 |
| 18 | Viral myocarditis_Homo sapiens_hsa05416 | 1.69587104 |
| 19 | Huntingtons disease_Homo sapiens_hsa05016 | 1.62255278 |
| 20 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.59194883 |
| 21 | Shigellosis_Homo sapiens_hsa05131 | 1.47446736 |
| 22 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.45903264 |
| 23 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.41729309 |
| 24 | Phototransduction_Homo sapiens_hsa04744 | 1.39733808 |
| 25 | Salmonella infection_Homo sapiens_hsa05132 | 1.35975631 |
| 26 | Measles_Homo sapiens_hsa05162 | 1.30582311 |
| 27 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.23427622 |
| 28 | Homologous recombination_Homo sapiens_hsa03440 | 1.22261674 |
| 29 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.18670299 |
| 30 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.15777091 |
| 31 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.15530141 |
| 32 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.13778115 |
| 33 | DNA replication_Homo sapiens_hsa03030 | 1.09447408 |
| 34 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.07801616 |
| 35 | Asthma_Homo sapiens_hsa05310 | 1.04183055 |
| 36 | Ribosome_Homo sapiens_hsa03010 | 1.03860230 |
| 37 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.98596389 |
| 38 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.94198668 |
| 39 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.89868796 |
| 40 | Mismatch repair_Homo sapiens_hsa03430 | 0.88912701 |
| 41 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.87061040 |
| 42 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.86441880 |
| 43 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.85161010 |
| 44 | Malaria_Homo sapiens_hsa05144 | 0.84928334 |
| 45 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.83909030 |
| 46 | Purine metabolism_Homo sapiens_hsa00230 | 0.81453636 |
| 47 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.81127291 |
| 48 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.72051813 |
| 49 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.68847413 |
| 50 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.67645443 |
| 51 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.67162453 |
| 52 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.65242981 |
| 53 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.62515264 |
| 54 | Taste transduction_Homo sapiens_hsa04742 | 0.61925828 |
| 55 | Olfactory transduction_Homo sapiens_hsa04740 | 0.57623330 |
| 56 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.57171636 |
| 57 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.55843632 |
| 58 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.52260735 |
| 59 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.51554371 |
| 60 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.49192540 |
| 61 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.48427238 |
| 62 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.48080372 |
| 63 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.41729426 |
| 64 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.41541079 |
| 65 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.40222836 |
| 66 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.38428637 |
| 67 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.37776954 |
| 68 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.37144935 |
| 69 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.35470158 |
| 70 | Prion diseases_Homo sapiens_hsa05020 | 0.35149670 |
| 71 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.34842989 |
| 72 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.34312020 |
| 73 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.34146273 |
| 74 | Apoptosis_Homo sapiens_hsa04210 | 0.33842342 |
| 75 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.33015615 |
| 76 | HTLV-I infection_Homo sapiens_hsa05166 | 0.29097261 |
| 77 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.28642815 |
| 78 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.27926973 |
| 79 | RNA degradation_Homo sapiens_hsa03018 | 0.27495806 |
| 80 | Alcoholism_Homo sapiens_hsa05034 | 0.27477888 |
| 81 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.26888250 |
| 82 | Endocytosis_Homo sapiens_hsa04144 | 0.25996994 |
| 83 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.25093845 |
| 84 | Peroxisome_Homo sapiens_hsa04146 | 0.24858935 |
| 85 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.24783230 |
| 86 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.23526699 |
| 87 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.22995985 |
| 88 | Metabolic pathways_Homo sapiens_hsa01100 | 0.22745511 |
| 89 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.18679651 |
| 90 | Leishmaniasis_Homo sapiens_hsa05140 | 0.18142913 |
| 91 | Retinol metabolism_Homo sapiens_hsa00830 | 0.17963080 |
| 92 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.16585266 |
| 93 | Platelet activation_Homo sapiens_hsa04611 | 0.16275677 |
| 94 | Renin secretion_Homo sapiens_hsa04924 | 0.15888304 |
| 95 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.15385878 |
| 96 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.15313622 |
| 97 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.15294590 |
| 98 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.14025816 |
| 99 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.12322271 |
| 100 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.10713282 |

