

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 8.24594781 |
| 2 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 7.34682167 |
| 3 | cytidine deamination (GO:0009972) | 6.75140835 |
| 4 | cytidine metabolic process (GO:0046087) | 6.75140835 |
| 5 | cytidine catabolic process (GO:0006216) | 6.75140835 |
| 6 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 5.84610239 |
| 7 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 5.23902006 |
| 8 | rRNA modification (GO:0000154) | 4.98972998 |
| 9 | rRNA methylation (GO:0031167) | 4.79525637 |
| 10 | sequestering of actin monomers (GO:0042989) | 4.46533312 |
| 11 | positive regulation of interleukin-8 secretion (GO:2000484) | 4.44124775 |
| 12 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.40331075 |
| 13 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 4.37577422 |
| 14 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.29186076 |
| 15 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.19322149 |
| 16 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.02556455 |
| 17 | ATP synthesis coupled proton transport (GO:0015986) | 4.00774644 |
| 18 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.00774644 |
| 19 | proteasome assembly (GO:0043248) | 3.93507027 |
| 20 | deoxyribonucleotide biosynthetic process (GO:0009263) | 3.92331661 |
| 21 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.87215666 |
| 22 | oxidative phosphorylation (GO:0006119) | 3.83146924 |
| 23 | 2-deoxyribonucleotide biosynthetic process (GO:0009265) | 3.80201223 |
| 24 | deoxyribose phosphate biosynthetic process (GO:0046385) | 3.80201223 |
| 25 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.77772256 |
| 26 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.77772256 |
| 27 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.76964484 |
| 28 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.76964484 |
| 29 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.76964484 |
| 30 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.76406295 |
| 31 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.67707402 |
| 32 | negative regulation of ligase activity (GO:0051352) | 3.67707402 |
| 33 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.66362344 |
| 34 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.66362344 |
| 35 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 3.66199181 |
| 36 | cytolysis (GO:0019835) | 3.65894557 |
| 37 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.64881627 |
| 38 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.64023819 |
| 39 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.60392092 |
| 40 | actin nucleation (GO:0045010) | 3.56834176 |
| 41 | respiratory electron transport chain (GO:0022904) | 3.56447455 |
| 42 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.55801753 |
| 43 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.53115521 |
| 44 | regulation of interleukin-8 secretion (GO:2000482) | 3.52420423 |
| 45 | electron transport chain (GO:0022900) | 3.50175149 |
| 46 | deoxyribonucleotide metabolic process (GO:0009262) | 3.47034102 |
| 47 | deoxyribonucleotide catabolic process (GO:0009264) | 3.45103974 |
| 48 | lipopolysaccharide biosynthetic process (GO:0009103) | 3.44289981 |
| 49 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.43366113 |
| 50 | deoxyribose phosphate metabolic process (GO:0019692) | 3.42764914 |
| 51 | T cell migration (GO:0072678) | 3.42515272 |
| 52 | cellular ketone body metabolic process (GO:0046950) | 3.42085453 |
| 53 | purine-containing compound salvage (GO:0043101) | 3.41127203 |
| 54 | mismatch repair (GO:0006298) | 3.39008761 |
| 55 | cellular response to interferon-beta (GO:0035458) | 3.35039314 |
| 56 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.32853867 |
| 57 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.30287247 |
| 58 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.30287247 |
| 59 | deoxyribose phosphate catabolic process (GO:0046386) | 3.29329855 |
| 60 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.24748032 |
| 61 | negative regulation of receptor activity (GO:2000272) | 3.22653873 |
| 62 | negative regulation of epidermal growth factor-activated receptor activity (GO:0007175) | 3.14211159 |
| 63 | respiratory chain complex IV assembly (GO:0008535) | 3.12023680 |
| 64 | regulation of cellular amine metabolic process (GO:0033238) | 3.10594783 |
| 65 | negative T cell selection (GO:0043383) | 3.10580064 |
| 66 | lipopolysaccharide metabolic process (GO:0008653) | 3.10153491 |
| 67 | response to interferon-beta (GO:0035456) | 3.08312101 |
| 68 | positive regulation of cell cycle arrest (GO:0071158) | 3.04431393 |
| 69 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.03591077 |
| 70 | ketone body metabolic process (GO:1902224) | 3.03239248 |
| 71 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 3.02764034 |
| 72 | 2-deoxyribonucleotide metabolic process (GO:0009394) | 3.02502880 |
| 73 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.02153426 |
| 74 | nucleobase biosynthetic process (GO:0046112) | 2.97652787 |
| 75 | telomere maintenance via semi-conservative replication (GO:0032201) | 2.94047142 |
| 76 | DNA damage response, detection of DNA damage (GO:0042769) | 2.93975738 |
| 77 | cytochrome complex assembly (GO:0017004) | 2.90921203 |
| 78 | mannosylation (GO:0097502) | 2.89970697 |
| 79 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 2.88375125 |
| 80 | DNA strand elongation involved in DNA replication (GO:0006271) | 2.86390866 |
| 81 | purine nucleobase biosynthetic process (GO:0009113) | 2.85868372 |
| 82 | positive regulation of ligase activity (GO:0051351) | 2.84999279 |
| 83 | DNA strand elongation (GO:0022616) | 2.79495678 |
| 84 | DNA double-strand break processing (GO:0000729) | 2.79468624 |
| 85 | cellular response to exogenous dsRNA (GO:0071360) | 2.77901461 |
| 86 | DNA ligation (GO:0006266) | 2.77479276 |
| 87 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 2.77111116 |
| 88 | ATP biosynthetic process (GO:0006754) | 2.75463916 |
| 89 | negative thymic T cell selection (GO:0045060) | 2.75200537 |
| 90 | telomere maintenance via recombination (GO:0000722) | 2.73496962 |
| 91 | reciprocal meiotic recombination (GO:0007131) | 2.72856882 |
| 92 | reciprocal DNA recombination (GO:0035825) | 2.72856882 |
| 93 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.72842079 |
| 94 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 2.72087902 |
| 95 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.70850220 |
| 96 | CENP-A containing nucleosome assembly (GO:0034080) | 2.68541305 |
| 97 | purine nucleotide salvage (GO:0032261) | 2.67858152 |
| 98 | regulation of cell cycle arrest (GO:0071156) | 2.66450501 |
| 99 | negative regulation of G1/S transition of mitotic cell cycle (GO:2000134) | 2.63234342 |
| 100 | negative regulation of cell cycle G1/S phase transition (GO:1902807) | 2.63234342 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 5.58341510 |
| 2 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 5.49801175 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.28787997 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.77170597 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.75880939 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.52778408 |
| 7 | IGF1R_20145208_ChIP-Seq_DFB_Human | 3.23161167 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.17815896 |
| 9 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.07234657 |
| 10 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.96674873 |
| 11 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.86702385 |
| 12 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.69729281 |
| 13 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.67702210 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.64572364 |
| 15 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.37043441 |
| 16 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.31506038 |
| 17 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.28702027 |
| 18 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.22589867 |
| 19 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.21597586 |
| 20 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.18528668 |
| 21 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.04575968 |
| 22 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.03665966 |
| 23 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.02511113 |
| 24 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.96649980 |
| 25 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.94506437 |
| 26 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.90162174 |
| 27 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.82139428 |
| 28 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.77228881 |
| 29 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.75196725 |
| 30 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.69853247 |
| 31 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.68014894 |
| 32 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.66462064 |
| 33 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.63427774 |
| 34 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.57659423 |
| 35 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.47610475 |
| 36 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.46348882 |
| 37 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.45439189 |
| 38 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.44042296 |
| 39 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.42499859 |
| 40 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.41643769 |
| 41 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.41212880 |
| 42 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.40929354 |
| 43 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.36337433 |
| 44 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.34360598 |
| 45 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.32809149 |
| 46 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.29970255 |
| 47 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.29837455 |
| 48 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.29564186 |
| 49 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.29030870 |
| 50 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.27841920 |
| 51 | GATA3_26560356_Chip-Seq_TH2_Human | 1.27817111 |
| 52 | MYB_26560356_Chip-Seq_TH2_Human | 1.27811621 |
| 53 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.25134456 |
| 54 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.25086331 |
| 55 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.24195926 |
| 56 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.23102578 |
| 57 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.23011118 |
| 58 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.22794733 |
| 59 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.19858933 |
| 60 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.19473453 |
| 61 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.18254810 |
| 62 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.18240502 |
| 63 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.16382294 |
| 64 | VDR_22108803_ChIP-Seq_LS180_Human | 1.13960371 |
| 65 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.12566082 |
| 66 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.11901687 |
| 67 | NCOR_22424771_ChIP-Seq_293T_Human | 1.10357403 |
| 68 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.10099260 |
| 69 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.05036386 |
| 70 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.04017905 |
| 71 | AR_20517297_ChIP-Seq_VCAP_Human | 1.03721348 |
| 72 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.03507604 |
| 73 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.02633666 |
| 74 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.02421211 |
| 75 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.01482080 |
| 76 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.01348806 |
| 77 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.00565339 |
| 78 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.99713328 |
| 79 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.97289431 |
| 80 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.95652801 |
| 81 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.95639073 |
| 82 | EWS_26573619_Chip-Seq_HEK293_Human | 0.94249949 |
| 83 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.93398817 |
| 84 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.93360197 |
| 85 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.91920666 |
| 86 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.91103038 |
| 87 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.90593317 |
| 88 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.90082278 |
| 89 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.90082278 |
| 90 | ERA_21632823_ChIP-Seq_H3396_Human | 0.89951854 |
| 91 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.89372304 |
| 92 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.88585528 |
| 93 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.88014049 |
| 94 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.87665657 |
| 95 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.86437578 |
| 96 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.86239353 |
| 97 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.84958518 |
| 98 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.84617330 |
| 99 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.84035530 |
| 100 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.83629253 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.12577417 |
| 2 | MP0005083_abnormal_biliary_tract | 2.84900991 |
| 3 | MP0003693_abnormal_embryo_hatching | 2.83928432 |
| 4 | MP0008877_abnormal_DNA_methylation | 2.69080059 |
| 5 | MP0002006_tumorigenesis | 2.66291098 |
| 6 | MP0010094_abnormal_chromosome_stability | 2.66035010 |
| 7 | MP0004145_abnormal_muscle_electrophysio | 2.61911178 |
| 8 | MP0002166_altered_tumor_susceptibility | 2.59704236 |
| 9 | MP0001986_abnormal_taste_sensitivity | 2.47068473 |
| 10 | MP0009785_altered_susceptibility_to | 2.47055335 |
| 11 | MP0005084_abnormal_gallbladder_morpholo | 2.37454034 |
| 12 | MP0006036_abnormal_mitochondrial_physio | 2.35358906 |
| 13 | MP0001835_abnormal_antigen_presentation | 2.33899534 |
| 14 | MP0006082_CNS_inflammation | 2.30010969 |
| 15 | MP0003195_calcinosis | 2.16176203 |
| 16 | MP0006072_abnormal_retinal_apoptosis | 2.11599869 |
| 17 | MP0004147_increased_porphyrin_level | 2.07088039 |
| 18 | MP0003787_abnormal_imprinting | 2.05521013 |
| 19 | MP0004957_abnormal_blastocyst_morpholog | 2.02779347 |
| 20 | MP0008058_abnormal_DNA_repair | 1.93360271 |
| 21 | MP0003866_abnormal_defecation | 1.92009902 |
| 22 | MP0009333_abnormal_splenocyte_physiolog | 1.85743302 |
| 23 | MP0003045_fibrosis | 1.82424408 |
| 24 | MP0003786_premature_aging | 1.76631316 |
| 25 | MP0005025_abnormal_response_to | 1.72030062 |
| 26 | MP0003763_abnormal_thymus_physiology | 1.67726022 |
| 27 | MP0005000_abnormal_immune_tolerance | 1.58481251 |
| 28 | MP0001661_extended_life_span | 1.56716714 |
| 29 | MP0000372_irregular_coat_pigmentation | 1.50063437 |
| 30 | MP0003111_abnormal_nucleus_morphology | 1.46919871 |
| 31 | MP0003448_altered_tumor_morphology | 1.40233288 |
| 32 | MP0005645_abnormal_hypothalamus_physiol | 1.38975976 |
| 33 | MP0001919_abnormal_reproductive_system | 1.38254521 |
| 34 | MP0002420_abnormal_adaptive_immunity | 1.33744855 |
| 35 | MP0008872_abnormal_physiological_respon | 1.29791175 |
| 36 | MP0005360_urolithiasis | 1.29701731 |
| 37 | MP0001800_abnormal_humoral_immune | 1.29071790 |
| 38 | MP0005636_abnormal_mineral_homeostasis | 1.27119369 |
| 39 | MP0001819_abnormal_immune_cell | 1.27013246 |
| 40 | MP0003718_maternal_effect | 1.26187694 |
| 41 | MP0001790_abnormal_immune_system | 1.24563892 |
| 42 | MP0005387_immune_system_phenotype | 1.24563892 |
| 43 | MP0003137_abnormal_impulse_conducting | 1.24207374 |
| 44 | MP0005551_abnormal_eye_electrophysiolog | 1.22654478 |
| 45 | MP0005253_abnormal_eye_physiology | 1.22503472 |
| 46 | MP0005389_reproductive_system_phenotype | 1.19457704 |
| 47 | MP0006276_abnormal_autonomic_nervous | 1.19140652 |
| 48 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.17396588 |
| 49 | MP0002148_abnormal_hypersensitivity_rea | 1.15690912 |
| 50 | MP0000685_abnormal_immune_system | 1.15334106 |
| 51 | MP0002723_abnormal_immune_serum | 1.14368547 |
| 52 | MP0004133_heterotaxia | 1.14059697 |
| 53 | MP0001968_abnormal_touch/_nociception | 1.12195291 |
| 54 | MP0003724_increased_susceptibility_to | 1.11798216 |
| 55 | MP0005167_abnormal_blood-brain_barrier | 1.10725641 |
| 56 | MP0001764_abnormal_homeostasis | 1.10656575 |
| 57 | MP0001929_abnormal_gametogenesis | 1.10010993 |
| 58 | MP0001542_abnormal_bone_strength | 1.08417946 |
| 59 | MP0003283_abnormal_digestive_organ | 1.08042098 |
| 60 | MP0002452_abnormal_antigen_presenting | 1.07653635 |
| 61 | MP0002160_abnormal_reproductive_system | 1.04482050 |
| 62 | MP0008875_abnormal_xenobiotic_pharmacok | 1.02546842 |
| 63 | MP0003646_muscle_fatigue | 1.01219196 |
| 64 | MP0000716_abnormal_immune_system | 1.01091164 |
| 65 | MP0000689_abnormal_spleen_morphology | 1.00434764 |
| 66 | MP0002693_abnormal_pancreas_physiology | 0.99787066 |
| 67 | MP0001905_abnormal_dopamine_level | 0.99158341 |
| 68 | MP0002398_abnormal_bone_marrow | 0.99012017 |
| 69 | MP0006035_abnormal_mitochondrial_morpho | 0.98152064 |
| 70 | MP0008007_abnormal_cellular_replicative | 0.96552846 |
| 71 | MP0002102_abnormal_ear_morphology | 0.95756608 |
| 72 | MP0000703_abnormal_thymus_morphology | 0.93993124 |
| 73 | MP0001119_abnormal_female_reproductive | 0.93938679 |
| 74 | MP0004215_abnormal_myocardial_fiber | 0.93805662 |
| 75 | MP0002722_abnormal_immune_system | 0.89924511 |
| 76 | MP0002210_abnormal_sex_determination | 0.89816972 |
| 77 | MP0001845_abnormal_inflammatory_respons | 0.88652986 |
| 78 | MP0010386_abnormal_urinary_bladder | 0.88639837 |
| 79 | MP0005379_endocrine/exocrine_gland_phen | 0.87674007 |
| 80 | MP0002019_abnormal_tumor_incidence | 0.87488594 |
| 81 | MP0005310_abnormal_salivary_gland | 0.84607363 |
| 82 | MP0003878_abnormal_ear_physiology | 0.84484456 |
| 83 | MP0005377_hearing/vestibular/ear_phenot | 0.84484456 |
| 84 | MP0009046_muscle_twitch | 0.83532897 |
| 85 | MP0003121_genomic_imprinting | 0.82476434 |
| 86 | MP0009643_abnormal_urine_homeostasis | 0.82440029 |
| 87 | MP0002272_abnormal_nervous_system | 0.82384236 |
| 88 | MP0008932_abnormal_embryonic_tissue | 0.82378696 |
| 89 | MP0002736_abnormal_nociception_after | 0.81352299 |
| 90 | MP0009745_abnormal_behavioral_response | 0.81309923 |
| 91 | MP0009763_increased_sensitivity_to | 0.80717658 |
| 92 | MP0002163_abnormal_gland_morphology | 0.79647387 |
| 93 | MP0003077_abnormal_cell_cycle | 0.77062348 |
| 94 | MP0002429_abnormal_blood_cell | 0.76448444 |
| 95 | MP0000653_abnormal_sex_gland | 0.74405419 |
| 96 | MP0002876_abnormal_thyroid_physiology | 0.74349275 |
| 97 | MP0005332_abnormal_amino_acid | 0.74153124 |
| 98 | MP0005395_other_phenotype | 0.73466680 |
| 99 | MP0002733_abnormal_thermal_nociception | 0.72315788 |
| 100 | MP0010329_abnormal_lipoprotein_level | 0.71433306 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Hepatocellular necrosis (HP:0001404) | 5.07995415 |
| 2 | Hepatic necrosis (HP:0002605) | 4.87841427 |
| 3 | Hypoproteinemia (HP:0003075) | 4.32208981 |
| 4 | Severe combined immunodeficiency (HP:0004430) | 4.12600187 |
| 5 | Mitochondrial inheritance (HP:0001427) | 4.12041121 |
| 6 | Increased CSF lactate (HP:0002490) | 3.62606272 |
| 7 | Acute necrotizing encephalopathy (HP:0006965) | 3.56707730 |
| 8 | 3-Methylglutaconic aciduria (HP:0003535) | 3.56144309 |
| 9 | Generalized aminoaciduria (HP:0002909) | 3.34360610 |
| 10 | Combined immunodeficiency (HP:0005387) | 3.32151902 |
| 11 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.30095242 |
| 12 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.19109872 |
| 13 | Aplastic anemia (HP:0001915) | 3.18452996 |
| 14 | Colon cancer (HP:0003003) | 3.06535151 |
| 15 | Thyroiditis (HP:0100646) | 3.05564850 |
| 16 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.03286740 |
| 17 | Acute encephalopathy (HP:0006846) | 2.98180220 |
| 18 | Type I transferrin isoform profile (HP:0003642) | 2.96895594 |
| 19 | Progressive macrocephaly (HP:0004481) | 2.94972913 |
| 20 | Abnormality of T cell number (HP:0011839) | 2.93814974 |
| 21 | IgG deficiency (HP:0004315) | 2.93154463 |
| 22 | Increased hepatocellular lipid droplets (HP:0006565) | 2.90573741 |
| 23 | Pancreatic cysts (HP:0001737) | 2.90170386 |
| 24 | T lymphocytopenia (HP:0005403) | 2.88384356 |
| 25 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.85089646 |
| 26 | Increased IgM level (HP:0003496) | 2.84570093 |
| 27 | Abnormality of B cell number (HP:0010975) | 2.76996082 |
| 28 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.76453967 |
| 29 | Lactic acidosis (HP:0003128) | 2.72379899 |
| 30 | Molar tooth sign on MRI (HP:0002419) | 2.71451112 |
| 31 | Abnormality of midbrain morphology (HP:0002418) | 2.71451112 |
| 32 | Hypothermia (HP:0002045) | 2.68966101 |
| 33 | Abnormality of eosinophils (HP:0001879) | 2.66936328 |
| 34 | True hermaphroditism (HP:0010459) | 2.62248605 |
| 35 | Autoimmune hemolytic anemia (HP:0001890) | 2.61681085 |
| 36 | Autoimmune thrombocytopenia (HP:0001973) | 2.60768844 |
| 37 | B lymphocytopenia (HP:0010976) | 2.58025479 |
| 38 | Renal Fanconi syndrome (HP:0001994) | 2.56225163 |
| 39 | Pancreatic fibrosis (HP:0100732) | 2.52124320 |
| 40 | Lipid accumulation in hepatocytes (HP:0006561) | 2.51927264 |
| 41 | Abnormal albumin level (HP:0012116) | 2.51007546 |
| 42 | Hypoalbuminemia (HP:0003073) | 2.51007546 |
| 43 | Abnormality of the labia minora (HP:0012880) | 2.48560456 |
| 44 | Cerebral edema (HP:0002181) | 2.46466962 |
| 45 | Increased serum lactate (HP:0002151) | 2.46325075 |
| 46 | Eosinophilia (HP:0001880) | 2.44889471 |
| 47 | Respiratory failure (HP:0002878) | 2.44171794 |
| 48 | Dicarboxylic aciduria (HP:0003215) | 2.43930235 |
| 49 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.43930235 |
| 50 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.41098151 |
| 51 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.41098151 |
| 52 | Increased intramyocellular lipid droplets (HP:0012240) | 2.39861343 |
| 53 | CNS demyelination (HP:0007305) | 2.37563680 |
| 54 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.34557333 |
| 55 | Pancytopenia (HP:0001876) | 2.34274384 |
| 56 | Neoplasm of the adrenal gland (HP:0100631) | 2.33053851 |
| 57 | Abnormality of the prostate (HP:0008775) | 2.32370355 |
| 58 | Meckel diverticulum (HP:0002245) | 2.32026675 |
| 59 | Attenuation of retinal blood vessels (HP:0007843) | 2.30059129 |
| 60 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.29806200 |
| 61 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.29806200 |
| 62 | Abnormal protein glycosylation (HP:0012346) | 2.29806200 |
| 63 | Abnormal glycosylation (HP:0012345) | 2.29806200 |
| 64 | Clubbing of toes (HP:0100760) | 2.29791308 |
| 65 | Amyotrophic lateral sclerosis (HP:0007354) | 2.29247599 |
| 66 | Abnormality of the ileum (HP:0001549) | 2.28290627 |
| 67 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.26900796 |
| 68 | Renal cortical cysts (HP:0000803) | 2.26026529 |
| 69 | Chronic diarrhea (HP:0002028) | 2.25298298 |
| 70 | Hemiplegia (HP:0002301) | 2.25088550 |
| 71 | Encephalitis (HP:0002383) | 2.22681383 |
| 72 | Constricted visual fields (HP:0001133) | 2.19825283 |
| 73 | Nephronophthisis (HP:0000090) | 2.15249837 |
| 74 | Petechiae (HP:0000967) | 2.12870002 |
| 75 | Optic disc pallor (HP:0000543) | 2.11116869 |
| 76 | Reduced antithrombin III activity (HP:0001976) | 2.07103040 |
| 77 | Exertional dyspnea (HP:0002875) | 2.06715781 |
| 78 | Abnormality of T cells (HP:0002843) | 2.06081405 |
| 79 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.05801103 |
| 80 | Short tibia (HP:0005736) | 1.99946965 |
| 81 | Hypoplasia of the pons (HP:0012110) | 1.98903996 |
| 82 | Microretrognathia (HP:0000308) | 1.96494276 |
| 83 | Tinnitus (HP:0000360) | 1.95809109 |
| 84 | Congenital stationary night blindness (HP:0007642) | 1.95440542 |
| 85 | Ketosis (HP:0001946) | 1.90701062 |
| 86 | Abnormality of the pons (HP:0007361) | 1.90517625 |
| 87 | Acute hepatic failure (HP:0006554) | 1.89851546 |
| 88 | Increased muscle lipid content (HP:0009058) | 1.84341356 |
| 89 | Cerebral palsy (HP:0100021) | 1.83836381 |
| 90 | Panhypogammaglobulinemia (HP:0003139) | 1.83313528 |
| 91 | Mesangial abnormality (HP:0001966) | 1.78621531 |
| 92 | Sclerocornea (HP:0000647) | 1.78461423 |
| 93 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.78052703 |
| 94 | Abnormality of chromosome stability (HP:0003220) | 1.77283079 |
| 95 | Lymphoma (HP:0002665) | 1.76820605 |
| 96 | Neuroendocrine neoplasm (HP:0100634) | 1.76229098 |
| 97 | Emotional lability (HP:0000712) | 1.75179926 |
| 98 | Abnormality of the preputium (HP:0100587) | 1.72535527 |
| 99 | Patellar aplasia (HP:0006443) | 1.72010014 |
| 100 | Type II lissencephaly (HP:0007260) | 1.71645310 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDR | 4.81195306 |
| 2 | TESK2 | 4.65588027 |
| 3 | VRK2 | 4.23765056 |
| 4 | ZAK | 2.83431538 |
| 5 | VRK1 | 2.67005251 |
| 6 | NUAK1 | 2.65570334 |
| 7 | TXK | 2.62152217 |
| 8 | BUB1 | 2.59515631 |
| 9 | BCKDK | 2.33191992 |
| 10 | CSNK1G3 | 2.24329922 |
| 11 | TLK1 | 2.16456791 |
| 12 | TAF1 | 2.15065885 |
| 13 | TAOK3 | 2.03991212 |
| 14 | CSNK1A1L | 2.01133384 |
| 15 | TESK1 | 1.89802050 |
| 16 | STK16 | 1.87379808 |
| 17 | PLK4 | 1.80249581 |
| 18 | BCR | 1.77019770 |
| 19 | LIMK1 | 1.75363478 |
| 20 | CSNK1G1 | 1.73071305 |
| 21 | NEK1 | 1.70122385 |
| 22 | CSNK1G2 | 1.65140378 |
| 23 | ITK | 1.58230654 |
| 24 | MST4 | 1.52995130 |
| 25 | TEC | 1.50979643 |
| 26 | CDC7 | 1.42330817 |
| 27 | SRPK1 | 1.28240861 |
| 28 | GRK1 | 1.20590606 |
| 29 | NME1 | 1.16432318 |
| 30 | MAP2K7 | 1.15684419 |
| 31 | ERBB3 | 1.14080819 |
| 32 | PLK3 | 1.11384193 |
| 33 | FRK | 1.08403374 |
| 34 | WEE1 | 1.06706544 |
| 35 | GRK5 | 1.05724996 |
| 36 | NEK9 | 1.03844847 |
| 37 | SMG1 | 1.03563750 |
| 38 | EIF2AK3 | 0.98122277 |
| 39 | ADRBK2 | 0.96662286 |
| 40 | MAPKAPK5 | 0.96332545 |
| 41 | DYRK2 | 0.95548205 |
| 42 | AURKA | 0.93368771 |
| 43 | TIE1 | 0.92744933 |
| 44 | CDK19 | 0.90066014 |
| 45 | DAPK1 | 0.87078493 |
| 46 | EIF2AK1 | 0.80674603 |
| 47 | TRIM28 | 0.80232658 |
| 48 | AURKB | 0.79860460 |
| 49 | EIF2AK2 | 0.78369451 |
| 50 | WNK3 | 0.76579384 |
| 51 | MAPK13 | 0.74942951 |
| 52 | ATR | 0.73857444 |
| 53 | SYK | 0.71276211 |
| 54 | MKNK1 | 0.69927279 |
| 55 | PLK1 | 0.67671409 |
| 56 | PRKCQ | 0.66461051 |
| 57 | WNK4 | 0.65029081 |
| 58 | MAP4K1 | 0.60120974 |
| 59 | BTK | 0.59593144 |
| 60 | RPS6KA4 | 0.59186021 |
| 61 | IRAK1 | 0.58008759 |
| 62 | MAPKAPK3 | 0.56576121 |
| 63 | BRSK2 | 0.54556405 |
| 64 | SIK2 | 0.53783392 |
| 65 | NTRK3 | 0.53735496 |
| 66 | LCK | 0.52431553 |
| 67 | CDK14 | 0.49541454 |
| 68 | CHEK2 | 0.49299813 |
| 69 | TNK2 | 0.49277626 |
| 70 | ZAP70 | 0.48422707 |
| 71 | MAP4K2 | 0.48363833 |
| 72 | RPS6KA5 | 0.46489346 |
| 73 | RAF1 | 0.45745058 |
| 74 | INSRR | 0.44795899 |
| 75 | LYN | 0.43571393 |
| 76 | CSNK1A1 | 0.42736101 |
| 77 | BRSK1 | 0.42617294 |
| 78 | CSNK2A1 | 0.41941130 |
| 79 | CDK11A | 0.41821388 |
| 80 | IRAK4 | 0.39902474 |
| 81 | CDK18 | 0.39180368 |
| 82 | PHKG1 | 0.38916990 |
| 83 | PHKG2 | 0.38916990 |
| 84 | TSSK6 | 0.38168922 |
| 85 | OXSR1 | 0.38047817 |
| 86 | CDK15 | 0.37898262 |
| 87 | MINK1 | 0.37375344 |
| 88 | CSK | 0.34622855 |
| 89 | STK39 | 0.34042130 |
| 90 | PAK1 | 0.33360765 |
| 91 | CCNB1 | 0.31137695 |
| 92 | PAK3 | 0.28384920 |
| 93 | PDK2 | 0.27944745 |
| 94 | PLK2 | 0.27504589 |
| 95 | PIK3CG | 0.26221926 |
| 96 | MAP2K6 | 0.25171903 |
| 97 | FYN | 0.24769940 |
| 98 | PRKACA | 0.24279841 |
| 99 | CAMKK2 | 0.23867193 |
| 100 | TRPM7 | 0.23282950 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.23326175 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.43695161 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.30460876 |
| 4 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.19316367 |
| 5 | DNA replication_Homo sapiens_hsa03030 | 3.07508605 |
| 6 | Parkinsons disease_Homo sapiens_hsa05012 | 2.91379121 |
| 7 | Mismatch repair_Homo sapiens_hsa03430 | 2.71786110 |
| 8 | Homologous recombination_Homo sapiens_hsa03440 | 2.60069693 |
| 9 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.39928131 |
| 10 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.31278396 |
| 11 | Protein export_Homo sapiens_hsa03060 | 2.20495696 |
| 12 | Base excision repair_Homo sapiens_hsa03410 | 2.09800400 |
| 13 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.02044807 |
| 14 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.94478632 |
| 15 | RNA polymerase_Homo sapiens_hsa03020 | 1.94192493 |
| 16 | Huntingtons disease_Homo sapiens_hsa05016 | 1.90309775 |
| 17 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.89170403 |
| 18 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.80755837 |
| 19 | Alzheimers disease_Homo sapiens_hsa05010 | 1.78820916 |
| 20 | Allograft rejection_Homo sapiens_hsa05330 | 1.77279349 |
| 21 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.74715963 |
| 22 | Spliceosome_Homo sapiens_hsa03040 | 1.58819388 |
| 23 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.53711493 |
| 24 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.53500807 |
| 25 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.52604508 |
| 26 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.51871066 |
| 27 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.50236838 |
| 28 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.49761985 |
| 29 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.41516496 |
| 30 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.39971058 |
| 31 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.39293683 |
| 32 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.36003187 |
| 33 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.35212008 |
| 34 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.31902918 |
| 35 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.31240619 |
| 36 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.28041980 |
| 37 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.21730837 |
| 38 | Ribosome_Homo sapiens_hsa03010 | 1.20227043 |
| 39 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.02774035 |
| 40 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.01342321 |
| 41 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.00300821 |
| 42 | Purine metabolism_Homo sapiens_hsa00230 | 0.98746319 |
| 43 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.93290559 |
| 44 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.92872144 |
| 45 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.92855252 |
| 46 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.90173964 |
| 47 | Phototransduction_Homo sapiens_hsa04744 | 0.90171150 |
| 48 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.89706424 |
| 49 | Peroxisome_Homo sapiens_hsa04146 | 0.88887400 |
| 50 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.83622215 |
| 51 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.75478468 |
| 52 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.75327976 |
| 53 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.75323582 |
| 54 | RNA degradation_Homo sapiens_hsa03018 | 0.73167958 |
| 55 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.72026326 |
| 56 | RNA transport_Homo sapiens_hsa03013 | 0.68426582 |
| 57 | Asthma_Homo sapiens_hsa05310 | 0.67419950 |
| 58 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.64302120 |
| 59 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.61199870 |
| 60 | Shigellosis_Homo sapiens_hsa05131 | 0.58609780 |
| 61 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.56206765 |
| 62 | Basal transcription factors_Homo sapiens_hsa03022 | 0.55354103 |
| 63 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.55223540 |
| 64 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.55117136 |
| 65 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.53734817 |
| 66 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.53710259 |
| 67 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.53172809 |
| 68 | Carbon metabolism_Homo sapiens_hsa01200 | 0.51969649 |
| 69 | Viral myocarditis_Homo sapiens_hsa05416 | 0.49955265 |
| 70 | Metabolic pathways_Homo sapiens_hsa01100 | 0.49043004 |
| 71 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.47061566 |
| 72 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.47011558 |
| 73 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.45063822 |
| 74 | Cell cycle_Homo sapiens_hsa04110 | 0.44973782 |
| 75 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.44022144 |
| 76 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.43729458 |
| 77 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.42995280 |
| 78 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.42127015 |
| 79 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.41061433 |
| 80 | Olfactory transduction_Homo sapiens_hsa04740 | 0.39550394 |
| 81 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.33145232 |
| 82 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.31827341 |
| 83 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.30746357 |
| 84 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.30342491 |
| 85 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.30228576 |
| 86 | Measles_Homo sapiens_hsa05162 | 0.29917035 |
| 87 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.29549374 |
| 88 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.27463374 |
| 89 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.27438542 |
| 90 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.25782738 |
| 91 | Salmonella infection_Homo sapiens_hsa05132 | 0.25415709 |
| 92 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.24115187 |
| 93 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.23047514 |
| 94 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.22924660 |
| 95 | Taste transduction_Homo sapiens_hsa04742 | 0.21974290 |
| 96 | Mineral absorption_Homo sapiens_hsa04978 | 0.21607687 |
| 97 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.19232035 |
| 98 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.17815540 |
| 99 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.17013857 |
| 100 | Alcoholism_Homo sapiens_hsa05034 | 0.16557207 |

