HMGN2P7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine ribonucleoside catabolic process (GO:0046133)9.39444229
2negative regulation by host of viral transcription (GO:0043922)6.10219299
3sequestering of actin monomers (GO:0042989)5.48601727
4regulation of activation of Janus kinase activity (GO:0010533)4.93170614
5pyrimidine nucleoside catabolic process (GO:0046135)4.90656355
6RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)4.87860215
7tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)4.87860215
8negative regulation of T cell apoptotic process (GO:0070233)4.66103871
9eosinophil chemotaxis (GO:0048245)4.58575382
10positive thymic T cell selection (GO:0045059)4.25923309
11regulation of chemokine-mediated signaling pathway (GO:0070099)4.17568545
12positive T cell selection (GO:0043368)4.15042039
13eosinophil migration (GO:0072677)4.14258711
14Arp2/3 complex-mediated actin nucleation (GO:0034314)3.95094214
15regulation of lymphocyte chemotaxis (GO:1901623)3.93502812
16positive regulation of interleukin-8 secretion (GO:2000484)3.86760244
17positive regulation of T cell chemotaxis (GO:0010820)3.79750319
18regulation of T cell chemotaxis (GO:0010819)3.79750319
19negative regulation of viral genome replication (GO:0045071)3.75623695
20macrophage chemotaxis (GO:0048246)3.74176924
21positive regulation of monocyte chemotaxis (GO:0090026)3.71956019
22adaptation of signaling pathway (GO:0023058)3.67837535
23actin nucleation (GO:0045010)3.64630081
24positive regulation of calcium-mediated signaling (GO:0050850)3.61609219
25adenosine metabolic process (GO:0046085)3.57250065
26DNA ligation (GO:0006266)3.55046221
27negative regulation of lymphocyte apoptotic process (GO:0070229)3.54252606
28positive regulation of translational initiation (GO:0045948)3.51604275
29negative regulation of stress fiber assembly (GO:0051497)3.51595155
30protein complex biogenesis (GO:0070271)3.51363197
31regulation of chronic inflammatory response (GO:0002676)3.49284626
32mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.43092714
33mitochondrial respiratory chain complex I assembly (GO:0032981)3.42854150
34NADH dehydrogenase complex assembly (GO:0010257)3.42854150
35mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.42854150
36regulation of mononuclear cell migration (GO:0071675)3.42228099
37regulation of cellular amino acid metabolic process (GO:0006521)3.35544029
38mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.32991218
39cellular response to interleukin-15 (GO:0071350)3.31010266
40positive regulation of natural killer cell mediated immunity (GO:0002717)3.24520300
41DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.23799783
42modulation by host of viral transcription (GO:0043921)3.21468232
43modulation by host of symbiont transcription (GO:0052472)3.21468232
44modulation of transcription in other organism involved in symbiotic interaction (GO:0052312)3.20738409
45cytolysis (GO:0019835)3.19244059
46positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)3.18855773
47T cell migration (GO:0072678)3.18813485
48mitochondrial respiratory chain complex assembly (GO:0033108)3.17898940
49antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.17546987
50pyrimidine-containing compound catabolic process (GO:0072529)3.16231636
51positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.13167674
52intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.12854909
53signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.12854909
54DNA demethylation (GO:0080111)3.11985834
55positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.10712988
56negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.09810861
57positive regulation of T cell apoptotic process (GO:0070234)3.09297712
58GPI anchor biosynthetic process (GO:0006506)3.09167405
59signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.07245026
60signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.07245026
61signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.07245026
62DNA dealkylation (GO:0035510)3.07148854
63proteasome assembly (GO:0043248)3.04673332
64positive regulation of phosphoprotein phosphatase activity (GO:0032516)3.04435251
65GPI anchor metabolic process (GO:0006505)3.04132240
66positive regulation of defense response to virus by host (GO:0002230)3.03855309
67positive regulation of lymphocyte migration (GO:2000403)3.03359114
68antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.02505534
69regulation of regulatory T cell differentiation (GO:0045589)3.00781357
70respiratory electron transport chain (GO:0022904)2.99206338
71purine nucleotide salvage (GO:0032261)2.94697680
72positive regulation of B cell differentiation (GO:0045579)2.94449877
73positive regulation of T cell mediated cytotoxicity (GO:0001916)2.92843099
74electron transport chain (GO:0022900)2.92179805
75regulation of interleukin-8 secretion (GO:2000482)2.91020352
76regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.90083852
77regulation of natural killer cell mediated immunity (GO:0002715)2.90083852
78signal transduction involved in DNA damage checkpoint (GO:0072422)2.89461962
79signal transduction involved in DNA integrity checkpoint (GO:0072401)2.89461962
80pyrimidine ribonucleoside metabolic process (GO:0046131)2.88785265
81signal transduction involved in cell cycle checkpoint (GO:0072395)2.85785263
82protein K6-linked ubiquitination (GO:0085020)2.85628004
83negative regulation of viral transcription (GO:0032897)2.85298749
84antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.84486585
85positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.83624082
86negative T cell selection (GO:0043383)2.81779359
87negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.78742847
88negative regulation of ligase activity (GO:0051352)2.78742847
89regulation of viral genome replication (GO:0045069)2.78629557
90ATP synthesis coupled proton transport (GO:0015986)2.78029480
91energy coupled proton transport, down electrochemical gradient (GO:0015985)2.78029480
92regulation of leukocyte mediated cytotoxicity (GO:0001910)2.77871580
93positive regulation of cell killing (GO:0031343)2.75264722
94negative regulation of oxidoreductase activity (GO:0051354)2.72815742
95negative regulation of cell killing (GO:0031342)2.71718004
96regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:004509111.4533202
97cytidine deamination (GO:0009972)10.8052092
98cytidine metabolic process (GO:0046087)10.8052092
99cytidine catabolic process (GO:0006216)10.8052092
100DNA deamination (GO:0045006)10.0341771

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human5.95804281
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse5.76125025
3NOTCH1_17114293_ChIP-ChIP_T-ALL_Human4.40889898
4VDR_22108803_ChIP-Seq_LS180_Human3.43997054
5ELF1_17652178_ChIP-ChIP_JURKAT_Human3.29497011
6IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.10811842
7KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.01809434
8GABP_17652178_ChIP-ChIP_JURKAT_Human2.83350524
9FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.81813737
10IRF8_22096565_ChIP-ChIP_GC-B_Human2.68107370
11HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.61937341
12STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.60084852
13SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.44245894
14IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.33154367
15ZNF274_21170338_ChIP-Seq_K562_Hela2.32109321
16EST1_17652178_ChIP-ChIP_JURKAT_Human2.31473245
17HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.30235270
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.20740919
19JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.19518380
20MYB_26560356_Chip-Seq_TH2_Human1.92266690
21VDR_23849224_ChIP-Seq_CD4+_Human1.88666360
22NOTCH1_21737748_ChIP-Seq_TLL_Human1.85945938
23TP53_22573176_ChIP-Seq_HFKS_Human1.83050463
24SRF_21415370_ChIP-Seq_HL-1_Mouse1.74241991
25PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.70699868
26HTT_18923047_ChIP-ChIP_STHdh_Human1.66575554
27FOXP3_21729870_ChIP-Seq_TREG_Human1.64353003
28MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.60192561
29LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.56040996
30IGF1R_20145208_ChIP-Seq_DFB_Human1.50450192
31RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.48214915
32IRF1_19129219_ChIP-ChIP_H3396_Human1.47313292
33EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.43386701
34ETS1_20019798_ChIP-Seq_JURKAT_Human1.40952325
35GATA3_26560356_Chip-Seq_TH2_Human1.39524398
36IRF8_21731497_ChIP-ChIP_J774_Mouse1.39249568
37CTBP1_25329375_ChIP-Seq_LNCAP_Human1.39226512
38TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.39067643
39FLI1_27457419_Chip-Seq_LIVER_Mouse1.36366709
40CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.36004388
41FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.34331963
42HOXB4_20404135_ChIP-ChIP_EML_Mouse1.33761043
43ERG_20517297_ChIP-Seq_VCAP_Human1.32567918
44STAT4_19710469_ChIP-ChIP_TH1__Mouse1.30534592
45SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.27792200
46MYC_18940864_ChIP-ChIP_HL60_Human1.27109734
47GATA3_27048872_Chip-Seq_THYMUS_Human1.24904308
48GBX2_23144817_ChIP-Seq_PC3_Human1.24061675
49TAF2_19829295_ChIP-Seq_ESCs_Human1.23933382
50PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.21799986
51ER_23166858_ChIP-Seq_MCF-7_Human1.19113518
52RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.18261643
53PCGF2_27294783_Chip-Seq_NPCs_Mouse1.16621360
54EZH2_22144423_ChIP-Seq_EOC_Human1.15965509
55FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.15789333
56ELK1_19687146_ChIP-ChIP_HELA_Human1.15782040
57EWS_26573619_Chip-Seq_HEK293_Human1.15524004
58CIITA_25753668_ChIP-Seq_RAJI_Human1.13829999
59FOXH1_21741376_ChIP-Seq_EPCs_Human1.13463607
60BCAT_22108803_ChIP-Seq_LS180_Human1.12422301
61RUNX_20019798_ChIP-Seq_JUKART_Human1.11207916
62MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.09090973
63EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.08141553
64AR_20517297_ChIP-Seq_VCAP_Human1.08056833
65NCOR_22424771_ChIP-Seq_293T_Human1.05757891
66POU3F2_20337985_ChIP-ChIP_501MEL_Human1.05685613
67PCGF2_27294783_Chip-Seq_ESCs_Mouse1.05413050
68CBP_20019798_ChIP-Seq_JUKART_Human1.04948045
69IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.04948045
70PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.04625089
71BMI1_23680149_ChIP-Seq_NPCS_Mouse1.04169693
72E2F4_17652178_ChIP-ChIP_JURKAT_Human1.04001557
73RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.03725598
74FOXA1_27270436_Chip-Seq_PROSTATE_Human1.02614950
75FOXA1_25329375_ChIP-Seq_VCAP_Human1.02614950
76CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.01664047
77NANOG_19829295_ChIP-Seq_ESCs_Human1.01568622
78SOX2_19829295_ChIP-Seq_ESCs_Human1.01568622
79CTBP2_25329375_ChIP-Seq_LNCAP_Human1.01325207
80HOXB7_26014856_ChIP-Seq_BT474_Human1.01304754
81MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.01179328
82AUTS2_25519132_ChIP-Seq_293T-REX_Human1.00457978
83NANOG_20526341_ChIP-Seq_ESCs_Human0.98460538
84CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.98246046
85MYB_26560356_Chip-Seq_TH1_Human0.96177538
86SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.94576691
87FUS_26573619_Chip-Seq_HEK293_Human0.94337327
88RXR_22108803_ChIP-Seq_LS180_Human0.93272892
89MYC_19829295_ChIP-Seq_ESCs_Human0.93174417
90EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.90752013
91POU5F1_16153702_ChIP-ChIP_HESCs_Human0.90329650
92YY1_22570637_ChIP-Seq_MALME-3M_Human0.90198058
93POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.90063551
94TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.89043043
95FOXA1_21572438_ChIP-Seq_LNCaP_Human0.87543286
96CREB1_15753290_ChIP-ChIP_HEK293T_Human0.86780009
97GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.86686185
98CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.85704532
99LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.85556635
100ERA_21632823_ChIP-Seq_H3396_Human0.85134332

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005671_abnormal_response_to5.12149437
2MP0005646_abnormal_pituitary_gland3.33486862
3MP0008995_early_reproductive_senescence2.94705489
4MP0009785_altered_susceptibility_to2.53464310
5MP0009333_abnormal_splenocyte_physiolog2.46213127
6MP0001661_extended_life_span2.38519202
7MP0004147_increased_porphyrin_level2.28713492
8MP0002837_dystrophic_cardiac_calcinosis2.27590227
9MP0001835_abnormal_antigen_presentation2.17212325
10MP0002736_abnormal_nociception_after2.12574887
11MP0006082_CNS_inflammation2.11558413
12MP0005000_abnormal_immune_tolerance1.96716244
13MP0003786_premature_aging1.96560936
14MP0002735_abnormal_chemical_nociception1.95886064
15MP0005360_urolithiasis1.86852439
16MP0002166_altered_tumor_susceptibility1.83883070
17MP0001919_abnormal_reproductive_system1.83215517
18MP0003763_abnormal_thymus_physiology1.82082597
19MP0002138_abnormal_hepatobiliary_system1.81288104
20MP0000372_irregular_coat_pigmentation1.80962439
21MP0002102_abnormal_ear_morphology1.78828724
22MP0003195_calcinosis1.72836634
23MP0002148_abnormal_hypersensitivity_rea1.72293798
24MP0001968_abnormal_touch/_nociception1.67237426
25MP0002876_abnormal_thyroid_physiology1.64857876
26MP0002234_abnormal_pharynx_morphology1.59468729
27MP0002420_abnormal_adaptive_immunity1.55808219
28MP0006072_abnormal_retinal_apoptosis1.54796555
29MP0002723_abnormal_immune_serum1.52688133
30MP0001819_abnormal_immune_cell1.50035943
31MP0002006_tumorigenesis1.48620023
32MP0000013_abnormal_adipose_tissue1.46534779
33MP0005551_abnormal_eye_electrophysiolog1.42906162
34MP0001800_abnormal_humoral_immune1.39488876
35MP0001984_abnormal_olfaction1.37793056
36MP0008877_abnormal_DNA_methylation1.36318985
37MP0005025_abnormal_response_to1.35994331
38MP0005253_abnormal_eye_physiology1.35733967
39MP0004043_abnormal_pH_regulation1.34742732
40MP0005389_reproductive_system_phenotype1.33547466
41MP0003806_abnormal_nucleotide_metabolis1.33149541
42MP0001905_abnormal_dopamine_level1.30560700
43MP0005377_hearing/vestibular/ear_phenot1.28302752
44MP0003878_abnormal_ear_physiology1.28302752
45MP0004885_abnormal_endolymph1.25114821
46MP0005075_abnormal_melanosome_morpholog1.24544646
47MP0005645_abnormal_hypothalamus_physiol1.24221642
48MP0008872_abnormal_physiological_respon1.22742919
49MP0002638_abnormal_pupillary_reflex1.21605623
50MP0005084_abnormal_gallbladder_morpholo1.20542841
51MP0000716_abnormal_immune_system1.18077453
52MP0005636_abnormal_mineral_homeostasis1.17711587
53MP0008873_increased_physiological_sensi1.17566957
54MP0002398_abnormal_bone_marrow1.16808268
55MP0001764_abnormal_homeostasis1.15993569
56MP0002822_catalepsy1.14583649
57MP0004185_abnormal_adipocyte_glucose1.13509226
58MP0001790_abnormal_immune_system1.13422397
59MP0005387_immune_system_phenotype1.13422397
60MP0001188_hyperpigmentation1.12999866
61MP0001485_abnormal_pinna_reflex1.10374239
62MP0002452_abnormal_antigen_presenting1.06723783
63MP0000703_abnormal_thymus_morphology1.06201537
64MP0003866_abnormal_defecation1.05648626
65MP0002693_abnormal_pancreas_physiology1.03857567
66MP0004145_abnormal_muscle_electrophysio1.03502715
67MP0000685_abnormal_immune_system1.02874135
68MP0009763_increased_sensitivity_to1.02510560
69MP0010386_abnormal_urinary_bladder1.02115256
70MP0001765_abnormal_ion_homeostasis1.01634897
71MP0001529_abnormal_vocalization0.99595234
72MP0002095_abnormal_skin_pigmentation0.99483911
73MP0003693_abnormal_embryo_hatching0.98998360
74MP0003045_fibrosis0.98959996
75MP0002722_abnormal_immune_system0.96904627
76MP0001486_abnormal_startle_reflex0.95704219
77MP0003448_altered_tumor_morphology0.95229464
78MP0008058_abnormal_DNA_repair0.93078277
79MP0003183_abnormal_peptide_metabolism0.92054732
80MP0009745_abnormal_behavioral_response0.91527468
81MP0000689_abnormal_spleen_morphology0.91001305
82MP0001845_abnormal_inflammatory_respons0.90845340
83MP0003283_abnormal_digestive_organ0.87584357
84MP0004134_abnormal_chest_morphology0.87426190
85MP0002429_abnormal_blood_cell0.85288502
86MP0001119_abnormal_female_reproductive0.85256569
87MP0001727_abnormal_embryo_implantation0.85148355
88MP0002909_abnormal_adrenal_gland0.85034769
89MP0001542_abnormal_bone_strength0.84217723
90MP0003724_increased_susceptibility_to0.81766744
91MP0005670_abnormal_white_adipose0.81589192
92MP0003137_abnormal_impulse_conducting0.81287075
93MP0005332_abnormal_amino_acid0.79934345
94MP0006276_abnormal_autonomic_nervous0.79463414
95MP0002272_abnormal_nervous_system0.78236923
96MP0004130_abnormal_muscle_cell0.77188082
97MP0009643_abnormal_urine_homeostasis0.76348246
98MP0004742_abnormal_vestibular_system0.75738509
99MP0005410_abnormal_fertilization0.75616618
100MP0002277_abnormal_respiratory_mucosa0.74224138

Predicted human phenotypes

RankGene SetZ-score
1Elevated erythrocyte sedimentation rate (HP:0003565)4.59266333
2T lymphocytopenia (HP:0005403)4.40627900
3Aplastic anemia (HP:0001915)4.32725241
4Severe combined immunodeficiency (HP:0004430)4.26556803
5Abnormality of T cell number (HP:0011839)4.14117181
6Abnormality of alanine metabolism (HP:0010916)3.97691151
7Hyperalaninemia (HP:0003348)3.97691151
8Abnormality of pyruvate family amino acid metabolism (HP:0010915)3.97691151
9Hypoproteinemia (HP:0003075)3.86509987
10Thyroiditis (HP:0100646)3.72966278
11Acute necrotizing encephalopathy (HP:0006965)3.51799633
12IgG deficiency (HP:0004315)3.48325699
13Methylmalonic acidemia (HP:0002912)3.47251498
14Combined immunodeficiency (HP:0005387)3.39967590
15Abnormal mitochondria in muscle tissue (HP:0008316)3.35557074
16Mitochondrial inheritance (HP:0001427)3.24163976
17Abnormality of eosinophils (HP:0001879)3.20525516
18B lymphocytopenia (HP:0010976)3.15432440
19Hepatocellular necrosis (HP:0001404)3.11416286
20Constricted visual fields (HP:0001133)3.11401891
21Generalized aminoaciduria (HP:0002909)3.00348143
22Progressive macrocephaly (HP:0004481)2.96832277
23Decreased electroretinogram (ERG) amplitude (HP:0000654)2.95512374
24Abnormality of B cell number (HP:0010975)2.92042865
25Autoimmune hemolytic anemia (HP:0001890)2.90230546
26Hepatic necrosis (HP:0002605)2.86423241
27Pigmentary retinal degeneration (HP:0001146)2.85781286
28Acute encephalopathy (HP:0006846)2.81713943
29Spontaneous hematomas (HP:0007420)2.80804477
30Cerebral edema (HP:0002181)2.80032284
31Congenital stationary night blindness (HP:0007642)2.77849899
32Abnormality of T cells (HP:0002843)2.74076920
333-Methylglutaconic aciduria (HP:0003535)2.64685260
34Increased CSF lactate (HP:0002490)2.64260141
35Congenital sensorineural hearing impairment (HP:0008527)2.63355553
36Attenuation of retinal blood vessels (HP:0007843)2.58535220
37Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.50006616
38Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.48805075
39Increased intramyocellular lipid droplets (HP:0012240)2.48428632
40Decreased activity of mitochondrial respiratory chain (HP:0008972)2.47015034
41Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.47015034
42Increased IgM level (HP:0003496)2.45389643
43Carpal bone hypoplasia (HP:0001498)2.44894225
44Increased serum lactate (HP:0002151)2.41643948
45Renal cortical cysts (HP:0000803)2.39904081
46Encephalitis (HP:0002383)2.36003751
47Methylmalonic aciduria (HP:0012120)2.33270978
48Hypergammaglobulinemia (HP:0010702)2.24633668
49Lactic acidosis (HP:0003128)2.24528619
50Abolished electroretinogram (ERG) (HP:0000550)2.20949771
51Pulmonary embolism (HP:0002204)2.19963149
52Leukocytosis (HP:0001974)2.18922063
53Eosinophilia (HP:0001880)2.18864373
54Abnormality of dicarboxylic acid metabolism (HP:0010995)2.18766009
55Dicarboxylic aciduria (HP:0003215)2.18766009
56Cerebral palsy (HP:0100021)2.18685325
57Petechiae (HP:0000967)2.17682721
58Absent rod-and cone-mediated responses on ERG (HP:0007688)2.15326533
59Hypoalbuminemia (HP:0003073)2.13858592
60Abnormal albumin level (HP:0012116)2.13858592
61Birth length less than 3rd percentile (HP:0003561)2.13287448
62Chronic diarrhea (HP:0002028)2.11222740
63Conjugated hyperbilirubinemia (HP:0002908)2.08191946
64Abnormal rod and cone electroretinograms (HP:0008323)2.07140235
65Type I transferrin isoform profile (HP:0003642)2.05374406
66Increased muscle lipid content (HP:0009058)2.04983593
67Abnormal delayed hypersensitivity skin test (HP:0002963)2.03462154
68Large eyes (HP:0001090)2.02298686
69Pendular nystagmus (HP:0012043)2.01044669
70Abnormality of the prostate (HP:0008775)1.99770755
71Granulocytopenia (HP:0001913)1.99156367
72Nephrogenic diabetes insipidus (HP:0009806)1.98182236
73Reduced antithrombin III activity (HP:0001976)1.96539584
74Abnormality of the vitamin B12 metabolism (HP:0004341)1.95151937
75Optic disc pallor (HP:0000543)1.94362927
76Abnormality of vitamin B metabolism (HP:0004340)1.93965296
77Oligomenorrhea (HP:0000876)1.93499832
78Pancytopenia (HP:0001876)1.92726733
79Pancreatic cysts (HP:0001737)1.92433163
80Hemoptysis (HP:0002105)1.90605953
81Anorexia (HP:0002039)1.89779156
82Renal Fanconi syndrome (HP:0001994)1.86873836
83Hypomagnesemia (HP:0002917)1.86786565
84Parakeratosis (HP:0001036)1.86398196
85Long clavicles (HP:0000890)1.85352347
86Hypoplasia of the thymus (HP:0000778)1.85153396
87Exercise intolerance (HP:0003546)1.82851861
88Hemiplegia (HP:0002301)1.80685865
89Metabolic acidosis (HP:0001942)1.80675190
90Abnormality of the renal collecting system (HP:0004742)1.80619338
91Medial flaring of the eyebrow (HP:0010747)1.79702850
92Chronic mucocutaneous candidiasis (HP:0002728)1.76271054
93Recurrent cutaneous fungal infections (HP:0011370)1.76271054
94Myositis (HP:0100614)1.74769316
95Decreased central vision (HP:0007663)1.74567318
96Increased hepatocellular lipid droplets (HP:0006565)1.74322423
97True hermaphroditism (HP:0010459)1.73804763
98Abnormality of urine glucose concentration (HP:0011016)1.73260870
99Glycosuria (HP:0003076)1.73260870
100Meningitis (HP:0001287)1.72722233

Predicted kinase interactions (KEA)

RankGene SetZ-score
1KDR5.86793694
2TESK25.48860397
3BCKDK4.45165090
4TXK3.89289531
5VRK22.45406426
6TESK12.32028572
7TNK22.22320174
8BUB12.18891939
9MAP4K12.05186946
10GRK71.83336219
11LIMK11.74256163
12ADRBK21.57998963
13WNK31.57179686
14ITK1.56720711
15NUAK11.53565280
16GRK61.50167797
17FRK1.50100519
18MAP3K111.47819258
19PRKCQ1.46349656
20MAP2K71.43258219
21WNK41.41855099
22VRK11.34247673
23GRK11.33600111
24CSNK1G31.23571427
25MAP3K121.22636875
26MST41.21131165
27TAOK31.16971676
28AURKA1.12608806
29ACVR1B1.12314484
30MAP4K21.01908910
31LCK0.99652993
32DYRK20.92975700
33CSNK1G20.92404950
34CSNK1A1L0.90891940
35SYK0.90382034
36FES0.89919706
37GRK50.88072837
38CSNK1G10.87589258
39MAPKAPK30.86837996
40MAP2K60.83578011
41CCNB10.81422745
42TLK10.79673272
43BRSK20.77991604
44TIE10.77858690
45ATR0.76618811
46MYLK0.74145092
47IKBKB0.71620615
48TBK10.70229818
49WEE10.68488992
50EIF2AK20.68435719
51BRSK10.66515514
52JAK30.65475828
53MAP3K30.65016176
54INSRR0.64793204
55SCYL20.64642883
56MAP3K40.62974305
57ERBB30.62803535
58ADRBK10.62505665
59LYN0.61414053
60CSNK1A10.60608820
61BCR0.60361692
62CSK0.60135073
63DAPK10.59391615
64TEC0.59321319
65PLK40.58248971
66BMPR1B0.57316062
67PINK10.55048512
68PIM20.54006587
69FGR0.53896238
70DAPK20.53666217
71RPS6KA40.51741755
72MAPK130.51290886
73NTRK20.51198388
74ARAF0.50865859
75AURKB0.50599511
76SRPK10.49309984
77BTK0.49084942
78CAMK2A0.48660868
79EPHA30.46566898
80RPS6KA50.46220971
81BMPR20.45802580
82CSF1R0.45344045
83PRKCH0.44580222
84EIF2AK30.44163862
85INSR0.42165223
86PRKACA0.41270309
87MAP2K30.40399883
88MAPKAPK20.38802754
89MATK0.38423507
90OBSCN0.36456791
91PRKCA0.34517836
92IGF1R0.33816391
93ERBB20.33434015
94CDK90.33208529
95PRKCI0.29784113
96PAK10.29685555
97PKN10.29633764
98CSNK2A10.29319285
99ZAP700.28525246
100FYN0.28458735

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030505.19359060
2Primary immunodeficiency_Homo sapiens_hsa053404.21006082
3Oxidative phosphorylation_Homo sapiens_hsa001903.51498785
4Graft-versus-host disease_Homo sapiens_hsa053323.11223807
5Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.96737664
6Parkinsons disease_Homo sapiens_hsa050122.74558905
7Antigen processing and presentation_Homo sapiens_hsa046122.66149004
8Protein export_Homo sapiens_hsa030602.59641197
9Autoimmune thyroid disease_Homo sapiens_hsa053202.33408314
10Allograft rejection_Homo sapiens_hsa053302.15398157
11Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.12225127
12Alzheimers disease_Homo sapiens_hsa050102.04672326
13Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.94913220
14Type I diabetes mellitus_Homo sapiens_hsa049401.93820130
15Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.84276647
16Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.73473410
17RNA polymerase_Homo sapiens_hsa030201.68385528
18One carbon pool by folate_Homo sapiens_hsa006701.67349102
19Huntingtons disease_Homo sapiens_hsa050161.66436637
20Rheumatoid arthritis_Homo sapiens_hsa053231.53371724
21Homologous recombination_Homo sapiens_hsa034401.44711170
22Hematopoietic cell lineage_Homo sapiens_hsa046401.43549395
23Fanconi anemia pathway_Homo sapiens_hsa034601.39087071
24T cell receptor signaling pathway_Homo sapiens_hsa046601.38065781
25Collecting duct acid secretion_Homo sapiens_hsa049661.35583275
26Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.34080164
27Propanoate metabolism_Homo sapiens_hsa006401.32484510
28Asthma_Homo sapiens_hsa053101.25529819
29Non-homologous end-joining_Homo sapiens_hsa034501.24448481
30SNARE interactions in vesicular transport_Homo sapiens_hsa041301.23108848
31Nicotine addiction_Homo sapiens_hsa050331.22745094
32Phototransduction_Homo sapiens_hsa047441.22733079
33Maturity onset diabetes of the young_Homo sapiens_hsa049501.21999814
34Sulfur metabolism_Homo sapiens_hsa009201.20238121
35Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.11778112
36Cardiac muscle contraction_Homo sapiens_hsa042601.06632317
37GABAergic synapse_Homo sapiens_hsa047270.99402381
38Nitrogen metabolism_Homo sapiens_hsa009100.99116276
39Intestinal immune network for IgA production_Homo sapiens_hsa046720.97128551
40DNA replication_Homo sapiens_hsa030300.96349368
41Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.93185003
42Butanoate metabolism_Homo sapiens_hsa006500.90780053
43Morphine addiction_Homo sapiens_hsa050320.86933652
44Taste transduction_Homo sapiens_hsa047420.85550087
45Salmonella infection_Homo sapiens_hsa051320.82712816
462-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.82221858
47Measles_Homo sapiens_hsa051620.78945079
48Peroxisome_Homo sapiens_hsa041460.77923554
49Pyrimidine metabolism_Homo sapiens_hsa002400.76985397
50Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.75892305
51Regulation of autophagy_Homo sapiens_hsa041400.73895465
52Linoleic acid metabolism_Homo sapiens_hsa005910.70196892
53RNA degradation_Homo sapiens_hsa030180.68874420
54Shigellosis_Homo sapiens_hsa051310.66480344
55Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.64625587
56Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.63952846
57Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.63581035
58Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.63560020
59NOD-like receptor signaling pathway_Homo sapiens_hsa046210.61570163
60Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.58445765
61Retinol metabolism_Homo sapiens_hsa008300.57941461
62Viral myocarditis_Homo sapiens_hsa054160.57757828
63Purine metabolism_Homo sapiens_hsa002300.57427660
64Spliceosome_Homo sapiens_hsa030400.56797480
65Steroid hormone biosynthesis_Homo sapiens_hsa001400.56454386
66Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.55817420
67Chemical carcinogenesis_Homo sapiens_hsa052040.55315819
68Mismatch repair_Homo sapiens_hsa034300.51117385
69Systemic lupus erythematosus_Homo sapiens_hsa053220.51091288
70Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.50306991
71Nucleotide excision repair_Homo sapiens_hsa034200.50141719
72Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.49359018
73Drug metabolism - other enzymes_Homo sapiens_hsa009830.49269538
74Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.47415926
75Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.44424889
76alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.44381694
77Tryptophan metabolism_Homo sapiens_hsa003800.42344538
78Olfactory transduction_Homo sapiens_hsa047400.42077975
79Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.41482304
80Metabolic pathways_Homo sapiens_hsa011000.40516936
81NF-kappa B signaling pathway_Homo sapiens_hsa040640.39381399
82Caffeine metabolism_Homo sapiens_hsa002320.38140869
83Staphylococcus aureus infection_Homo sapiens_hsa051500.37385659
84RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.35819917
85Basal transcription factors_Homo sapiens_hsa030220.35797851
86Cysteine and methionine metabolism_Homo sapiens_hsa002700.35732224
87Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.34909634
88Chemokine signaling pathway_Homo sapiens_hsa040620.33423692
89Serotonergic synapse_Homo sapiens_hsa047260.32613167
90Herpes simplex infection_Homo sapiens_hsa051680.30067637
91Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.29600619
92Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.29044009
93Alcoholism_Homo sapiens_hsa050340.28279503
94Prion diseases_Homo sapiens_hsa050200.27627242
95Sulfur relay system_Homo sapiens_hsa041220.26524359
96Epstein-Barr virus infection_Homo sapiens_hsa051690.26377130
97Selenocompound metabolism_Homo sapiens_hsa004500.24480897
98Malaria_Homo sapiens_hsa051440.21225158
99Ribosome_Homo sapiens_hsa030100.21153522
100Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.21041985

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »