

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 9.39444229 |
| 2 | negative regulation by host of viral transcription (GO:0043922) | 6.10219299 |
| 3 | sequestering of actin monomers (GO:0042989) | 5.48601727 |
| 4 | regulation of activation of Janus kinase activity (GO:0010533) | 4.93170614 |
| 5 | pyrimidine nucleoside catabolic process (GO:0046135) | 4.90656355 |
| 6 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.87860215 |
| 7 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.87860215 |
| 8 | negative regulation of T cell apoptotic process (GO:0070233) | 4.66103871 |
| 9 | eosinophil chemotaxis (GO:0048245) | 4.58575382 |
| 10 | positive thymic T cell selection (GO:0045059) | 4.25923309 |
| 11 | regulation of chemokine-mediated signaling pathway (GO:0070099) | 4.17568545 |
| 12 | positive T cell selection (GO:0043368) | 4.15042039 |
| 13 | eosinophil migration (GO:0072677) | 4.14258711 |
| 14 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.95094214 |
| 15 | regulation of lymphocyte chemotaxis (GO:1901623) | 3.93502812 |
| 16 | positive regulation of interleukin-8 secretion (GO:2000484) | 3.86760244 |
| 17 | positive regulation of T cell chemotaxis (GO:0010820) | 3.79750319 |
| 18 | regulation of T cell chemotaxis (GO:0010819) | 3.79750319 |
| 19 | negative regulation of viral genome replication (GO:0045071) | 3.75623695 |
| 20 | macrophage chemotaxis (GO:0048246) | 3.74176924 |
| 21 | positive regulation of monocyte chemotaxis (GO:0090026) | 3.71956019 |
| 22 | adaptation of signaling pathway (GO:0023058) | 3.67837535 |
| 23 | actin nucleation (GO:0045010) | 3.64630081 |
| 24 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.61609219 |
| 25 | adenosine metabolic process (GO:0046085) | 3.57250065 |
| 26 | DNA ligation (GO:0006266) | 3.55046221 |
| 27 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 3.54252606 |
| 28 | positive regulation of translational initiation (GO:0045948) | 3.51604275 |
| 29 | negative regulation of stress fiber assembly (GO:0051497) | 3.51595155 |
| 30 | protein complex biogenesis (GO:0070271) | 3.51363197 |
| 31 | regulation of chronic inflammatory response (GO:0002676) | 3.49284626 |
| 32 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.43092714 |
| 33 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.42854150 |
| 34 | NADH dehydrogenase complex assembly (GO:0010257) | 3.42854150 |
| 35 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.42854150 |
| 36 | regulation of mononuclear cell migration (GO:0071675) | 3.42228099 |
| 37 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.35544029 |
| 38 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.32991218 |
| 39 | cellular response to interleukin-15 (GO:0071350) | 3.31010266 |
| 40 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.24520300 |
| 41 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.23799783 |
| 42 | modulation by host of viral transcription (GO:0043921) | 3.21468232 |
| 43 | modulation by host of symbiont transcription (GO:0052472) | 3.21468232 |
| 44 | modulation of transcription in other organism involved in symbiotic interaction (GO:0052312) | 3.20738409 |
| 45 | cytolysis (GO:0019835) | 3.19244059 |
| 46 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.18855773 |
| 47 | T cell migration (GO:0072678) | 3.18813485 |
| 48 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.17898940 |
| 49 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.17546987 |
| 50 | pyrimidine-containing compound catabolic process (GO:0072529) | 3.16231636 |
| 51 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.13167674 |
| 52 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.12854909 |
| 53 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.12854909 |
| 54 | DNA demethylation (GO:0080111) | 3.11985834 |
| 55 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.10712988 |
| 56 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.09810861 |
| 57 | positive regulation of T cell apoptotic process (GO:0070234) | 3.09297712 |
| 58 | GPI anchor biosynthetic process (GO:0006506) | 3.09167405 |
| 59 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.07245026 |
| 60 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.07245026 |
| 61 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.07245026 |
| 62 | DNA dealkylation (GO:0035510) | 3.07148854 |
| 63 | proteasome assembly (GO:0043248) | 3.04673332 |
| 64 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 3.04435251 |
| 65 | GPI anchor metabolic process (GO:0006505) | 3.04132240 |
| 66 | positive regulation of defense response to virus by host (GO:0002230) | 3.03855309 |
| 67 | positive regulation of lymphocyte migration (GO:2000403) | 3.03359114 |
| 68 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.02505534 |
| 69 | regulation of regulatory T cell differentiation (GO:0045589) | 3.00781357 |
| 70 | respiratory electron transport chain (GO:0022904) | 2.99206338 |
| 71 | purine nucleotide salvage (GO:0032261) | 2.94697680 |
| 72 | positive regulation of B cell differentiation (GO:0045579) | 2.94449877 |
| 73 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.92843099 |
| 74 | electron transport chain (GO:0022900) | 2.92179805 |
| 75 | regulation of interleukin-8 secretion (GO:2000482) | 2.91020352 |
| 76 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.90083852 |
| 77 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.90083852 |
| 78 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.89461962 |
| 79 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.89461962 |
| 80 | pyrimidine ribonucleoside metabolic process (GO:0046131) | 2.88785265 |
| 81 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.85785263 |
| 82 | protein K6-linked ubiquitination (GO:0085020) | 2.85628004 |
| 83 | negative regulation of viral transcription (GO:0032897) | 2.85298749 |
| 84 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.84486585 |
| 85 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.83624082 |
| 86 | negative T cell selection (GO:0043383) | 2.81779359 |
| 87 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.78742847 |
| 88 | negative regulation of ligase activity (GO:0051352) | 2.78742847 |
| 89 | regulation of viral genome replication (GO:0045069) | 2.78629557 |
| 90 | ATP synthesis coupled proton transport (GO:0015986) | 2.78029480 |
| 91 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.78029480 |
| 92 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.77871580 |
| 93 | positive regulation of cell killing (GO:0031343) | 2.75264722 |
| 94 | negative regulation of oxidoreductase activity (GO:0051354) | 2.72815742 |
| 95 | negative regulation of cell killing (GO:0031342) | 2.71718004 |
| 96 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 11.4533202 |
| 97 | cytidine deamination (GO:0009972) | 10.8052092 |
| 98 | cytidine metabolic process (GO:0046087) | 10.8052092 |
| 99 | cytidine catabolic process (GO:0006216) | 10.8052092 |
| 100 | DNA deamination (GO:0045006) | 10.0341771 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.95804281 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.76125025 |
| 3 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 4.40889898 |
| 4 | VDR_22108803_ChIP-Seq_LS180_Human | 3.43997054 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.29497011 |
| 6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.10811842 |
| 7 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.01809434 |
| 8 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.83350524 |
| 9 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.81813737 |
| 10 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.68107370 |
| 11 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.61937341 |
| 12 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.60084852 |
| 13 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.44245894 |
| 14 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.33154367 |
| 15 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.32109321 |
| 16 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.31473245 |
| 17 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.30235270 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.20740919 |
| 19 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.19518380 |
| 20 | MYB_26560356_Chip-Seq_TH2_Human | 1.92266690 |
| 21 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.88666360 |
| 22 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.85945938 |
| 23 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.83050463 |
| 24 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.74241991 |
| 25 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.70699868 |
| 26 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.66575554 |
| 27 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.64353003 |
| 28 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.60192561 |
| 29 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.56040996 |
| 30 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.50450192 |
| 31 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.48214915 |
| 32 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.47313292 |
| 33 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.43386701 |
| 34 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.40952325 |
| 35 | GATA3_26560356_Chip-Seq_TH2_Human | 1.39524398 |
| 36 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.39249568 |
| 37 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.39226512 |
| 38 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.39067643 |
| 39 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.36366709 |
| 40 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.36004388 |
| 41 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.34331963 |
| 42 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.33761043 |
| 43 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.32567918 |
| 44 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.30534592 |
| 45 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.27792200 |
| 46 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.27109734 |
| 47 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.24904308 |
| 48 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.24061675 |
| 49 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.23933382 |
| 50 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.21799986 |
| 51 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.19113518 |
| 52 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.18261643 |
| 53 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.16621360 |
| 54 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.15965509 |
| 55 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.15789333 |
| 56 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.15782040 |
| 57 | EWS_26573619_Chip-Seq_HEK293_Human | 1.15524004 |
| 58 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.13829999 |
| 59 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.13463607 |
| 60 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.12422301 |
| 61 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.11207916 |
| 62 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.09090973 |
| 63 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.08141553 |
| 64 | AR_20517297_ChIP-Seq_VCAP_Human | 1.08056833 |
| 65 | NCOR_22424771_ChIP-Seq_293T_Human | 1.05757891 |
| 66 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.05685613 |
| 67 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.05413050 |
| 68 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.04948045 |
| 69 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.04948045 |
| 70 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.04625089 |
| 71 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.04169693 |
| 72 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.04001557 |
| 73 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.03725598 |
| 74 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.02614950 |
| 75 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.02614950 |
| 76 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.01664047 |
| 77 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.01568622 |
| 78 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.01568622 |
| 79 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.01325207 |
| 80 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.01304754 |
| 81 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.01179328 |
| 82 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.00457978 |
| 83 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.98460538 |
| 84 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.98246046 |
| 85 | MYB_26560356_Chip-Seq_TH1_Human | 0.96177538 |
| 86 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.94576691 |
| 87 | FUS_26573619_Chip-Seq_HEK293_Human | 0.94337327 |
| 88 | RXR_22108803_ChIP-Seq_LS180_Human | 0.93272892 |
| 89 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.93174417 |
| 90 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.90752013 |
| 91 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.90329650 |
| 92 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.90198058 |
| 93 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.90063551 |
| 94 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.89043043 |
| 95 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.87543286 |
| 96 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 0.86780009 |
| 97 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.86686185 |
| 98 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.85704532 |
| 99 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.85556635 |
| 100 | ERA_21632823_ChIP-Seq_H3396_Human | 0.85134332 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 5.12149437 |
| 2 | MP0005646_abnormal_pituitary_gland | 3.33486862 |
| 3 | MP0008995_early_reproductive_senescence | 2.94705489 |
| 4 | MP0009785_altered_susceptibility_to | 2.53464310 |
| 5 | MP0009333_abnormal_splenocyte_physiolog | 2.46213127 |
| 6 | MP0001661_extended_life_span | 2.38519202 |
| 7 | MP0004147_increased_porphyrin_level | 2.28713492 |
| 8 | MP0002837_dystrophic_cardiac_calcinosis | 2.27590227 |
| 9 | MP0001835_abnormal_antigen_presentation | 2.17212325 |
| 10 | MP0002736_abnormal_nociception_after | 2.12574887 |
| 11 | MP0006082_CNS_inflammation | 2.11558413 |
| 12 | MP0005000_abnormal_immune_tolerance | 1.96716244 |
| 13 | MP0003786_premature_aging | 1.96560936 |
| 14 | MP0002735_abnormal_chemical_nociception | 1.95886064 |
| 15 | MP0005360_urolithiasis | 1.86852439 |
| 16 | MP0002166_altered_tumor_susceptibility | 1.83883070 |
| 17 | MP0001919_abnormal_reproductive_system | 1.83215517 |
| 18 | MP0003763_abnormal_thymus_physiology | 1.82082597 |
| 19 | MP0002138_abnormal_hepatobiliary_system | 1.81288104 |
| 20 | MP0000372_irregular_coat_pigmentation | 1.80962439 |
| 21 | MP0002102_abnormal_ear_morphology | 1.78828724 |
| 22 | MP0003195_calcinosis | 1.72836634 |
| 23 | MP0002148_abnormal_hypersensitivity_rea | 1.72293798 |
| 24 | MP0001968_abnormal_touch/_nociception | 1.67237426 |
| 25 | MP0002876_abnormal_thyroid_physiology | 1.64857876 |
| 26 | MP0002234_abnormal_pharynx_morphology | 1.59468729 |
| 27 | MP0002420_abnormal_adaptive_immunity | 1.55808219 |
| 28 | MP0006072_abnormal_retinal_apoptosis | 1.54796555 |
| 29 | MP0002723_abnormal_immune_serum | 1.52688133 |
| 30 | MP0001819_abnormal_immune_cell | 1.50035943 |
| 31 | MP0002006_tumorigenesis | 1.48620023 |
| 32 | MP0000013_abnormal_adipose_tissue | 1.46534779 |
| 33 | MP0005551_abnormal_eye_electrophysiolog | 1.42906162 |
| 34 | MP0001800_abnormal_humoral_immune | 1.39488876 |
| 35 | MP0001984_abnormal_olfaction | 1.37793056 |
| 36 | MP0008877_abnormal_DNA_methylation | 1.36318985 |
| 37 | MP0005025_abnormal_response_to | 1.35994331 |
| 38 | MP0005253_abnormal_eye_physiology | 1.35733967 |
| 39 | MP0004043_abnormal_pH_regulation | 1.34742732 |
| 40 | MP0005389_reproductive_system_phenotype | 1.33547466 |
| 41 | MP0003806_abnormal_nucleotide_metabolis | 1.33149541 |
| 42 | MP0001905_abnormal_dopamine_level | 1.30560700 |
| 43 | MP0005377_hearing/vestibular/ear_phenot | 1.28302752 |
| 44 | MP0003878_abnormal_ear_physiology | 1.28302752 |
| 45 | MP0004885_abnormal_endolymph | 1.25114821 |
| 46 | MP0005075_abnormal_melanosome_morpholog | 1.24544646 |
| 47 | MP0005645_abnormal_hypothalamus_physiol | 1.24221642 |
| 48 | MP0008872_abnormal_physiological_respon | 1.22742919 |
| 49 | MP0002638_abnormal_pupillary_reflex | 1.21605623 |
| 50 | MP0005084_abnormal_gallbladder_morpholo | 1.20542841 |
| 51 | MP0000716_abnormal_immune_system | 1.18077453 |
| 52 | MP0005636_abnormal_mineral_homeostasis | 1.17711587 |
| 53 | MP0008873_increased_physiological_sensi | 1.17566957 |
| 54 | MP0002398_abnormal_bone_marrow | 1.16808268 |
| 55 | MP0001764_abnormal_homeostasis | 1.15993569 |
| 56 | MP0002822_catalepsy | 1.14583649 |
| 57 | MP0004185_abnormal_adipocyte_glucose | 1.13509226 |
| 58 | MP0001790_abnormal_immune_system | 1.13422397 |
| 59 | MP0005387_immune_system_phenotype | 1.13422397 |
| 60 | MP0001188_hyperpigmentation | 1.12999866 |
| 61 | MP0001485_abnormal_pinna_reflex | 1.10374239 |
| 62 | MP0002452_abnormal_antigen_presenting | 1.06723783 |
| 63 | MP0000703_abnormal_thymus_morphology | 1.06201537 |
| 64 | MP0003866_abnormal_defecation | 1.05648626 |
| 65 | MP0002693_abnormal_pancreas_physiology | 1.03857567 |
| 66 | MP0004145_abnormal_muscle_electrophysio | 1.03502715 |
| 67 | MP0000685_abnormal_immune_system | 1.02874135 |
| 68 | MP0009763_increased_sensitivity_to | 1.02510560 |
| 69 | MP0010386_abnormal_urinary_bladder | 1.02115256 |
| 70 | MP0001765_abnormal_ion_homeostasis | 1.01634897 |
| 71 | MP0001529_abnormal_vocalization | 0.99595234 |
| 72 | MP0002095_abnormal_skin_pigmentation | 0.99483911 |
| 73 | MP0003693_abnormal_embryo_hatching | 0.98998360 |
| 74 | MP0003045_fibrosis | 0.98959996 |
| 75 | MP0002722_abnormal_immune_system | 0.96904627 |
| 76 | MP0001486_abnormal_startle_reflex | 0.95704219 |
| 77 | MP0003448_altered_tumor_morphology | 0.95229464 |
| 78 | MP0008058_abnormal_DNA_repair | 0.93078277 |
| 79 | MP0003183_abnormal_peptide_metabolism | 0.92054732 |
| 80 | MP0009745_abnormal_behavioral_response | 0.91527468 |
| 81 | MP0000689_abnormal_spleen_morphology | 0.91001305 |
| 82 | MP0001845_abnormal_inflammatory_respons | 0.90845340 |
| 83 | MP0003283_abnormal_digestive_organ | 0.87584357 |
| 84 | MP0004134_abnormal_chest_morphology | 0.87426190 |
| 85 | MP0002429_abnormal_blood_cell | 0.85288502 |
| 86 | MP0001119_abnormal_female_reproductive | 0.85256569 |
| 87 | MP0001727_abnormal_embryo_implantation | 0.85148355 |
| 88 | MP0002909_abnormal_adrenal_gland | 0.85034769 |
| 89 | MP0001542_abnormal_bone_strength | 0.84217723 |
| 90 | MP0003724_increased_susceptibility_to | 0.81766744 |
| 91 | MP0005670_abnormal_white_adipose | 0.81589192 |
| 92 | MP0003137_abnormal_impulse_conducting | 0.81287075 |
| 93 | MP0005332_abnormal_amino_acid | 0.79934345 |
| 94 | MP0006276_abnormal_autonomic_nervous | 0.79463414 |
| 95 | MP0002272_abnormal_nervous_system | 0.78236923 |
| 96 | MP0004130_abnormal_muscle_cell | 0.77188082 |
| 97 | MP0009643_abnormal_urine_homeostasis | 0.76348246 |
| 98 | MP0004742_abnormal_vestibular_system | 0.75738509 |
| 99 | MP0005410_abnormal_fertilization | 0.75616618 |
| 100 | MP0002277_abnormal_respiratory_mucosa | 0.74224138 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.59266333 |
| 2 | T lymphocytopenia (HP:0005403) | 4.40627900 |
| 3 | Aplastic anemia (HP:0001915) | 4.32725241 |
| 4 | Severe combined immunodeficiency (HP:0004430) | 4.26556803 |
| 5 | Abnormality of T cell number (HP:0011839) | 4.14117181 |
| 6 | Abnormality of alanine metabolism (HP:0010916) | 3.97691151 |
| 7 | Hyperalaninemia (HP:0003348) | 3.97691151 |
| 8 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.97691151 |
| 9 | Hypoproteinemia (HP:0003075) | 3.86509987 |
| 10 | Thyroiditis (HP:0100646) | 3.72966278 |
| 11 | Acute necrotizing encephalopathy (HP:0006965) | 3.51799633 |
| 12 | IgG deficiency (HP:0004315) | 3.48325699 |
| 13 | Methylmalonic acidemia (HP:0002912) | 3.47251498 |
| 14 | Combined immunodeficiency (HP:0005387) | 3.39967590 |
| 15 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.35557074 |
| 16 | Mitochondrial inheritance (HP:0001427) | 3.24163976 |
| 17 | Abnormality of eosinophils (HP:0001879) | 3.20525516 |
| 18 | B lymphocytopenia (HP:0010976) | 3.15432440 |
| 19 | Hepatocellular necrosis (HP:0001404) | 3.11416286 |
| 20 | Constricted visual fields (HP:0001133) | 3.11401891 |
| 21 | Generalized aminoaciduria (HP:0002909) | 3.00348143 |
| 22 | Progressive macrocephaly (HP:0004481) | 2.96832277 |
| 23 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.95512374 |
| 24 | Abnormality of B cell number (HP:0010975) | 2.92042865 |
| 25 | Autoimmune hemolytic anemia (HP:0001890) | 2.90230546 |
| 26 | Hepatic necrosis (HP:0002605) | 2.86423241 |
| 27 | Pigmentary retinal degeneration (HP:0001146) | 2.85781286 |
| 28 | Acute encephalopathy (HP:0006846) | 2.81713943 |
| 29 | Spontaneous hematomas (HP:0007420) | 2.80804477 |
| 30 | Cerebral edema (HP:0002181) | 2.80032284 |
| 31 | Congenital stationary night blindness (HP:0007642) | 2.77849899 |
| 32 | Abnormality of T cells (HP:0002843) | 2.74076920 |
| 33 | 3-Methylglutaconic aciduria (HP:0003535) | 2.64685260 |
| 34 | Increased CSF lactate (HP:0002490) | 2.64260141 |
| 35 | Congenital sensorineural hearing impairment (HP:0008527) | 2.63355553 |
| 36 | Attenuation of retinal blood vessels (HP:0007843) | 2.58535220 |
| 37 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.50006616 |
| 38 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.48805075 |
| 39 | Increased intramyocellular lipid droplets (HP:0012240) | 2.48428632 |
| 40 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.47015034 |
| 41 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.47015034 |
| 42 | Increased IgM level (HP:0003496) | 2.45389643 |
| 43 | Carpal bone hypoplasia (HP:0001498) | 2.44894225 |
| 44 | Increased serum lactate (HP:0002151) | 2.41643948 |
| 45 | Renal cortical cysts (HP:0000803) | 2.39904081 |
| 46 | Encephalitis (HP:0002383) | 2.36003751 |
| 47 | Methylmalonic aciduria (HP:0012120) | 2.33270978 |
| 48 | Hypergammaglobulinemia (HP:0010702) | 2.24633668 |
| 49 | Lactic acidosis (HP:0003128) | 2.24528619 |
| 50 | Abolished electroretinogram (ERG) (HP:0000550) | 2.20949771 |
| 51 | Pulmonary embolism (HP:0002204) | 2.19963149 |
| 52 | Leukocytosis (HP:0001974) | 2.18922063 |
| 53 | Eosinophilia (HP:0001880) | 2.18864373 |
| 54 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.18766009 |
| 55 | Dicarboxylic aciduria (HP:0003215) | 2.18766009 |
| 56 | Cerebral palsy (HP:0100021) | 2.18685325 |
| 57 | Petechiae (HP:0000967) | 2.17682721 |
| 58 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.15326533 |
| 59 | Hypoalbuminemia (HP:0003073) | 2.13858592 |
| 60 | Abnormal albumin level (HP:0012116) | 2.13858592 |
| 61 | Birth length less than 3rd percentile (HP:0003561) | 2.13287448 |
| 62 | Chronic diarrhea (HP:0002028) | 2.11222740 |
| 63 | Conjugated hyperbilirubinemia (HP:0002908) | 2.08191946 |
| 64 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.07140235 |
| 65 | Type I transferrin isoform profile (HP:0003642) | 2.05374406 |
| 66 | Increased muscle lipid content (HP:0009058) | 2.04983593 |
| 67 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.03462154 |
| 68 | Large eyes (HP:0001090) | 2.02298686 |
| 69 | Pendular nystagmus (HP:0012043) | 2.01044669 |
| 70 | Abnormality of the prostate (HP:0008775) | 1.99770755 |
| 71 | Granulocytopenia (HP:0001913) | 1.99156367 |
| 72 | Nephrogenic diabetes insipidus (HP:0009806) | 1.98182236 |
| 73 | Reduced antithrombin III activity (HP:0001976) | 1.96539584 |
| 74 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.95151937 |
| 75 | Optic disc pallor (HP:0000543) | 1.94362927 |
| 76 | Abnormality of vitamin B metabolism (HP:0004340) | 1.93965296 |
| 77 | Oligomenorrhea (HP:0000876) | 1.93499832 |
| 78 | Pancytopenia (HP:0001876) | 1.92726733 |
| 79 | Pancreatic cysts (HP:0001737) | 1.92433163 |
| 80 | Hemoptysis (HP:0002105) | 1.90605953 |
| 81 | Anorexia (HP:0002039) | 1.89779156 |
| 82 | Renal Fanconi syndrome (HP:0001994) | 1.86873836 |
| 83 | Hypomagnesemia (HP:0002917) | 1.86786565 |
| 84 | Parakeratosis (HP:0001036) | 1.86398196 |
| 85 | Long clavicles (HP:0000890) | 1.85352347 |
| 86 | Hypoplasia of the thymus (HP:0000778) | 1.85153396 |
| 87 | Exercise intolerance (HP:0003546) | 1.82851861 |
| 88 | Hemiplegia (HP:0002301) | 1.80685865 |
| 89 | Metabolic acidosis (HP:0001942) | 1.80675190 |
| 90 | Abnormality of the renal collecting system (HP:0004742) | 1.80619338 |
| 91 | Medial flaring of the eyebrow (HP:0010747) | 1.79702850 |
| 92 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.76271054 |
| 93 | Recurrent cutaneous fungal infections (HP:0011370) | 1.76271054 |
| 94 | Myositis (HP:0100614) | 1.74769316 |
| 95 | Decreased central vision (HP:0007663) | 1.74567318 |
| 96 | Increased hepatocellular lipid droplets (HP:0006565) | 1.74322423 |
| 97 | True hermaphroditism (HP:0010459) | 1.73804763 |
| 98 | Abnormality of urine glucose concentration (HP:0011016) | 1.73260870 |
| 99 | Glycosuria (HP:0003076) | 1.73260870 |
| 100 | Meningitis (HP:0001287) | 1.72722233 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDR | 5.86793694 |
| 2 | TESK2 | 5.48860397 |
| 3 | BCKDK | 4.45165090 |
| 4 | TXK | 3.89289531 |
| 5 | VRK2 | 2.45406426 |
| 6 | TESK1 | 2.32028572 |
| 7 | TNK2 | 2.22320174 |
| 8 | BUB1 | 2.18891939 |
| 9 | MAP4K1 | 2.05186946 |
| 10 | GRK7 | 1.83336219 |
| 11 | LIMK1 | 1.74256163 |
| 12 | ADRBK2 | 1.57998963 |
| 13 | WNK3 | 1.57179686 |
| 14 | ITK | 1.56720711 |
| 15 | NUAK1 | 1.53565280 |
| 16 | GRK6 | 1.50167797 |
| 17 | FRK | 1.50100519 |
| 18 | MAP3K11 | 1.47819258 |
| 19 | PRKCQ | 1.46349656 |
| 20 | MAP2K7 | 1.43258219 |
| 21 | WNK4 | 1.41855099 |
| 22 | VRK1 | 1.34247673 |
| 23 | GRK1 | 1.33600111 |
| 24 | CSNK1G3 | 1.23571427 |
| 25 | MAP3K12 | 1.22636875 |
| 26 | MST4 | 1.21131165 |
| 27 | TAOK3 | 1.16971676 |
| 28 | AURKA | 1.12608806 |
| 29 | ACVR1B | 1.12314484 |
| 30 | MAP4K2 | 1.01908910 |
| 31 | LCK | 0.99652993 |
| 32 | DYRK2 | 0.92975700 |
| 33 | CSNK1G2 | 0.92404950 |
| 34 | CSNK1A1L | 0.90891940 |
| 35 | SYK | 0.90382034 |
| 36 | FES | 0.89919706 |
| 37 | GRK5 | 0.88072837 |
| 38 | CSNK1G1 | 0.87589258 |
| 39 | MAPKAPK3 | 0.86837996 |
| 40 | MAP2K6 | 0.83578011 |
| 41 | CCNB1 | 0.81422745 |
| 42 | TLK1 | 0.79673272 |
| 43 | BRSK2 | 0.77991604 |
| 44 | TIE1 | 0.77858690 |
| 45 | ATR | 0.76618811 |
| 46 | MYLK | 0.74145092 |
| 47 | IKBKB | 0.71620615 |
| 48 | TBK1 | 0.70229818 |
| 49 | WEE1 | 0.68488992 |
| 50 | EIF2AK2 | 0.68435719 |
| 51 | BRSK1 | 0.66515514 |
| 52 | JAK3 | 0.65475828 |
| 53 | MAP3K3 | 0.65016176 |
| 54 | INSRR | 0.64793204 |
| 55 | SCYL2 | 0.64642883 |
| 56 | MAP3K4 | 0.62974305 |
| 57 | ERBB3 | 0.62803535 |
| 58 | ADRBK1 | 0.62505665 |
| 59 | LYN | 0.61414053 |
| 60 | CSNK1A1 | 0.60608820 |
| 61 | BCR | 0.60361692 |
| 62 | CSK | 0.60135073 |
| 63 | DAPK1 | 0.59391615 |
| 64 | TEC | 0.59321319 |
| 65 | PLK4 | 0.58248971 |
| 66 | BMPR1B | 0.57316062 |
| 67 | PINK1 | 0.55048512 |
| 68 | PIM2 | 0.54006587 |
| 69 | FGR | 0.53896238 |
| 70 | DAPK2 | 0.53666217 |
| 71 | RPS6KA4 | 0.51741755 |
| 72 | MAPK13 | 0.51290886 |
| 73 | NTRK2 | 0.51198388 |
| 74 | ARAF | 0.50865859 |
| 75 | AURKB | 0.50599511 |
| 76 | SRPK1 | 0.49309984 |
| 77 | BTK | 0.49084942 |
| 78 | CAMK2A | 0.48660868 |
| 79 | EPHA3 | 0.46566898 |
| 80 | RPS6KA5 | 0.46220971 |
| 81 | BMPR2 | 0.45802580 |
| 82 | CSF1R | 0.45344045 |
| 83 | PRKCH | 0.44580222 |
| 84 | EIF2AK3 | 0.44163862 |
| 85 | INSR | 0.42165223 |
| 86 | PRKACA | 0.41270309 |
| 87 | MAP2K3 | 0.40399883 |
| 88 | MAPKAPK2 | 0.38802754 |
| 89 | MATK | 0.38423507 |
| 90 | OBSCN | 0.36456791 |
| 91 | PRKCA | 0.34517836 |
| 92 | IGF1R | 0.33816391 |
| 93 | ERBB2 | 0.33434015 |
| 94 | CDK9 | 0.33208529 |
| 95 | PRKCI | 0.29784113 |
| 96 | PAK1 | 0.29685555 |
| 97 | PKN1 | 0.29633764 |
| 98 | CSNK2A1 | 0.29319285 |
| 99 | ZAP70 | 0.28525246 |
| 100 | FYN | 0.28458735 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.19359060 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.21006082 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.51498785 |
| 4 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.11223807 |
| 5 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.96737664 |
| 6 | Parkinsons disease_Homo sapiens_hsa05012 | 2.74558905 |
| 7 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.66149004 |
| 8 | Protein export_Homo sapiens_hsa03060 | 2.59641197 |
| 9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.33408314 |
| 10 | Allograft rejection_Homo sapiens_hsa05330 | 2.15398157 |
| 11 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.12225127 |
| 12 | Alzheimers disease_Homo sapiens_hsa05010 | 2.04672326 |
| 13 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.94913220 |
| 14 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.93820130 |
| 15 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.84276647 |
| 16 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.73473410 |
| 17 | RNA polymerase_Homo sapiens_hsa03020 | 1.68385528 |
| 18 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.67349102 |
| 19 | Huntingtons disease_Homo sapiens_hsa05016 | 1.66436637 |
| 20 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.53371724 |
| 21 | Homologous recombination_Homo sapiens_hsa03440 | 1.44711170 |
| 22 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.43549395 |
| 23 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.39087071 |
| 24 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.38065781 |
| 25 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.35583275 |
| 26 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.34080164 |
| 27 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.32484510 |
| 28 | Asthma_Homo sapiens_hsa05310 | 1.25529819 |
| 29 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.24448481 |
| 30 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.23108848 |
| 31 | Nicotine addiction_Homo sapiens_hsa05033 | 1.22745094 |
| 32 | Phototransduction_Homo sapiens_hsa04744 | 1.22733079 |
| 33 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.21999814 |
| 34 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.20238121 |
| 35 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.11778112 |
| 36 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.06632317 |
| 37 | GABAergic synapse_Homo sapiens_hsa04727 | 0.99402381 |
| 38 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.99116276 |
| 39 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.97128551 |
| 40 | DNA replication_Homo sapiens_hsa03030 | 0.96349368 |
| 41 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.93185003 |
| 42 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.90780053 |
| 43 | Morphine addiction_Homo sapiens_hsa05032 | 0.86933652 |
| 44 | Taste transduction_Homo sapiens_hsa04742 | 0.85550087 |
| 45 | Salmonella infection_Homo sapiens_hsa05132 | 0.82712816 |
| 46 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.82221858 |
| 47 | Measles_Homo sapiens_hsa05162 | 0.78945079 |
| 48 | Peroxisome_Homo sapiens_hsa04146 | 0.77923554 |
| 49 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.76985397 |
| 50 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.75892305 |
| 51 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.73895465 |
| 52 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.70196892 |
| 53 | RNA degradation_Homo sapiens_hsa03018 | 0.68874420 |
| 54 | Shigellosis_Homo sapiens_hsa05131 | 0.66480344 |
| 55 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.64625587 |
| 56 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.63952846 |
| 57 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.63581035 |
| 58 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.63560020 |
| 59 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.61570163 |
| 60 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.58445765 |
| 61 | Retinol metabolism_Homo sapiens_hsa00830 | 0.57941461 |
| 62 | Viral myocarditis_Homo sapiens_hsa05416 | 0.57757828 |
| 63 | Purine metabolism_Homo sapiens_hsa00230 | 0.57427660 |
| 64 | Spliceosome_Homo sapiens_hsa03040 | 0.56797480 |
| 65 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.56454386 |
| 66 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.55817420 |
| 67 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.55315819 |
| 68 | Mismatch repair_Homo sapiens_hsa03430 | 0.51117385 |
| 69 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.51091288 |
| 70 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.50306991 |
| 71 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.50141719 |
| 72 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.49359018 |
| 73 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.49269538 |
| 74 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.47415926 |
| 75 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.44424889 |
| 76 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.44381694 |
| 77 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.42344538 |
| 78 | Olfactory transduction_Homo sapiens_hsa04740 | 0.42077975 |
| 79 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.41482304 |
| 80 | Metabolic pathways_Homo sapiens_hsa01100 | 0.40516936 |
| 81 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.39381399 |
| 82 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.38140869 |
| 83 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.37385659 |
| 84 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.35819917 |
| 85 | Basal transcription factors_Homo sapiens_hsa03022 | 0.35797851 |
| 86 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.35732224 |
| 87 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.34909634 |
| 88 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.33423692 |
| 89 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.32613167 |
| 90 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.30067637 |
| 91 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.29600619 |
| 92 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.29044009 |
| 93 | Alcoholism_Homo sapiens_hsa05034 | 0.28279503 |
| 94 | Prion diseases_Homo sapiens_hsa05020 | 0.27627242 |
| 95 | Sulfur relay system_Homo sapiens_hsa04122 | 0.26524359 |
| 96 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.26377130 |
| 97 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.24480897 |
| 98 | Malaria_Homo sapiens_hsa05144 | 0.21225158 |
| 99 | Ribosome_Homo sapiens_hsa03010 | 0.21153522 |
| 100 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.21041985 |

