

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | synaptic vesicle maturation (GO:0016188) | 6.85736616 |
| 2 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 6.07544852 |
| 3 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 5.66089318 |
| 4 | pyrimidine nucleobase catabolic process (GO:0006208) | 5.60964126 |
| 5 | glutamate secretion (GO:0014047) | 5.59794103 |
| 6 | postsynaptic membrane organization (GO:0001941) | 5.51767890 |
| 7 | neuron cell-cell adhesion (GO:0007158) | 5.45131853 |
| 8 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 5.44479620 |
| 9 | regulation of synaptic vesicle exocytosis (GO:2000300) | 5.39874439 |
| 10 | synaptic vesicle exocytosis (GO:0016079) | 5.35194834 |
| 11 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 5.22427095 |
| 12 | vocalization behavior (GO:0071625) | 5.12968835 |
| 13 | protein localization to synapse (GO:0035418) | 5.10162042 |
| 14 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 4.99846362 |
| 15 | exploration behavior (GO:0035640) | 4.81030616 |
| 16 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 4.72976640 |
| 17 | neurotransmitter secretion (GO:0007269) | 4.72028223 |
| 18 | regulation of synaptic vesicle transport (GO:1902803) | 4.65160583 |
| 19 | layer formation in cerebral cortex (GO:0021819) | 4.61296998 |
| 20 | locomotory exploration behavior (GO:0035641) | 4.60068438 |
| 21 | dendritic spine morphogenesis (GO:0060997) | 4.59980769 |
| 22 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 4.58936381 |
| 23 | nucleobase catabolic process (GO:0046113) | 4.58730541 |
| 24 | synaptic transmission, glutamatergic (GO:0035249) | 4.58504872 |
| 25 | establishment of mitochondrion localization (GO:0051654) | 4.53714762 |
| 26 | presynaptic membrane assembly (GO:0097105) | 4.45346525 |
| 27 | neuron recognition (GO:0008038) | 4.45312320 |
| 28 | glutamate receptor signaling pathway (GO:0007215) | 4.45006250 |
| 29 | cell migration in hindbrain (GO:0021535) | 4.39681821 |
| 30 | neurotransmitter-gated ion channel clustering (GO:0072578) | 4.36567500 |
| 31 | presynaptic membrane organization (GO:0097090) | 4.28760358 |
| 32 | axonal fasciculation (GO:0007413) | 4.28416783 |
| 33 | regulation of synapse structural plasticity (GO:0051823) | 4.24066486 |
| 34 | auditory behavior (GO:0031223) | 4.13018490 |
| 35 | neuron-neuron synaptic transmission (GO:0007270) | 4.12844305 |
| 36 | regulation of neuronal synaptic plasticity (GO:0048168) | 4.08537806 |
| 37 | regulation of glutamate receptor signaling pathway (GO:1900449) | 4.07723697 |
| 38 | cellular potassium ion homeostasis (GO:0030007) | 4.03950106 |
| 39 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 3.95809222 |
| 40 | mitochondrion transport along microtubule (GO:0047497) | 3.95809222 |
| 41 | gamma-aminobutyric acid transport (GO:0015812) | 3.90999324 |
| 42 | positive regulation of synapse maturation (GO:0090129) | 3.90841163 |
| 43 | cerebellar granule cell differentiation (GO:0021707) | 3.84577145 |
| 44 | transmission of nerve impulse (GO:0019226) | 3.79061218 |
| 45 | neurotransmitter transport (GO:0006836) | 3.77654586 |
| 46 | neuronal action potential propagation (GO:0019227) | 3.72766204 |
| 47 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.69911122 |
| 48 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.68526113 |
| 49 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.65916581 |
| 50 | dendrite morphogenesis (GO:0048813) | 3.64332678 |
| 51 | positive regulation of membrane potential (GO:0045838) | 3.61616945 |
| 52 | central nervous system projection neuron axonogenesis (GO:0021952) | 3.60941305 |
| 53 | regulation of vesicle fusion (GO:0031338) | 3.60751155 |
| 54 | sodium ion export (GO:0071436) | 3.58381926 |
| 55 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 3.56055163 |
| 56 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.55482501 |
| 57 | regulation of postsynaptic membrane potential (GO:0060078) | 3.54834820 |
| 58 | regulation of neurotransmitter secretion (GO:0046928) | 3.54006721 |
| 59 | positive regulation of synapse assembly (GO:0051965) | 3.50485984 |
| 60 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 3.50027116 |
| 61 | response to auditory stimulus (GO:0010996) | 3.50007762 |
| 62 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.49394335 |
| 63 | regulation of neurotransmitter levels (GO:0001505) | 3.48743277 |
| 64 | neuronal ion channel clustering (GO:0045161) | 3.48353299 |
| 65 | synapse assembly (GO:0007416) | 3.46887722 |
| 66 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 3.46666344 |
| 67 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 3.45812545 |
| 68 | positive regulation of dendritic spine development (GO:0060999) | 3.40901728 |
| 69 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.36847324 |
| 70 | startle response (GO:0001964) | 3.34869119 |
| 71 | membrane depolarization during action potential (GO:0086010) | 3.33680306 |
| 72 | regulation of dendritic spine morphogenesis (GO:0061001) | 3.32567201 |
| 73 | long-term memory (GO:0007616) | 3.32106890 |
| 74 | membrane depolarization (GO:0051899) | 3.31210870 |
| 75 | synaptic vesicle endocytosis (GO:0048488) | 3.28273277 |
| 76 | cerebellar Purkinje cell differentiation (GO:0021702) | 3.26226378 |
| 77 | dendritic spine organization (GO:0097061) | 3.24917818 |
| 78 | neuromuscular synaptic transmission (GO:0007274) | 3.23873050 |
| 79 | neuromuscular process controlling balance (GO:0050885) | 3.21323946 |
| 80 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 3.20247130 |
| 81 | mechanosensory behavior (GO:0007638) | 3.20131888 |
| 82 | regulation of neurotransmitter transport (GO:0051588) | 3.18983106 |
| 83 | negative regulation of dendrite morphogenesis (GO:0050774) | 3.17429857 |
| 84 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 3.14494574 |
| 85 | axon extension (GO:0048675) | 3.14485976 |
| 86 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.14476446 |
| 87 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 3.13786472 |
| 88 | regulation of synapse maturation (GO:0090128) | 3.12047156 |
| 89 | regulation of synaptic plasticity (GO:0048167) | 3.11402162 |
| 90 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.10455965 |
| 91 | regulation of voltage-gated calcium channel activity (GO:1901385) | 3.09247718 |
| 92 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.06635462 |
| 93 | synapse organization (GO:0050808) | 3.05998058 |
| 94 | neurofilament cytoskeleton organization (GO:0060052) | 3.04823424 |
| 95 | positive regulation of neurotransmitter transport (GO:0051590) | 3.03716062 |
| 96 | regulation of dendritic spine development (GO:0060998) | 2.98843079 |
| 97 | adult walking behavior (GO:0007628) | 2.97794239 |
| 98 | cerebellar Purkinje cell layer development (GO:0021680) | 2.95298810 |
| 99 | negative regulation of dendrite development (GO:2000171) | 2.94672898 |
| 100 | learning (GO:0007612) | 2.94410479 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 6.30743389 |
| 2 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 4.38279389 |
| 3 | REST_21632747_ChIP-Seq_MESCs_Mouse | 3.17188863 |
| 4 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.12820995 |
| 5 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 3.12464660 |
| 6 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 3.02496269 |
| 7 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.89117082 |
| 8 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.89076513 |
| 9 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.80814024 |
| 10 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.64128972 |
| 11 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.64128972 |
| 12 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.64045516 |
| 13 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.60852356 |
| 14 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.56483668 |
| 15 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.56399832 |
| 16 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.52664604 |
| 17 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.47266347 |
| 18 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.45482067 |
| 19 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.44296726 |
| 20 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.43065953 |
| 21 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.42660622 |
| 22 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.40430518 |
| 23 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.35875214 |
| 24 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.34640323 |
| 25 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.32432700 |
| 26 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.10048684 |
| 27 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.98846179 |
| 28 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.88195024 |
| 29 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.85787476 |
| 30 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.80929026 |
| 31 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.79921270 |
| 32 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.77760883 |
| 33 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.77139485 |
| 34 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.70793558 |
| 35 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.62279965 |
| 36 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.61544529 |
| 37 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.61263733 |
| 38 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.56285603 |
| 39 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.53951474 |
| 40 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.53814742 |
| 41 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.52706642 |
| 42 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.52051426 |
| 43 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.49282765 |
| 44 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.47478874 |
| 45 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.44003537 |
| 46 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.41798328 |
| 47 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.36158859 |
| 48 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.31662895 |
| 49 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.29061324 |
| 50 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.24933864 |
| 51 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.24616582 |
| 52 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.24256214 |
| 53 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.23790247 |
| 54 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.21892461 |
| 55 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.20052398 |
| 56 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.19428937 |
| 57 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.15779045 |
| 58 | AR_19668381_ChIP-Seq_PC3_Human | 1.12793462 |
| 59 | * SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.12674204 |
| 60 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.11912332 |
| 61 | * SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.11257751 |
| 62 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.10983796 |
| 63 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.10983796 |
| 64 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.09773106 |
| 65 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.09059408 |
| 66 | P300_19829295_ChIP-Seq_ESCs_Human | 1.07503716 |
| 67 | * SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.07028244 |
| 68 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.06487429 |
| 69 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.04910901 |
| 70 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.01587547 |
| 71 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.01259934 |
| 72 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.00721754 |
| 73 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.00291167 |
| 74 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.99795973 |
| 75 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.98333919 |
| 76 | KDM2B_26808549_Chip-Seq_K562_Human | 0.98169236 |
| 77 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.97715629 |
| 78 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.95678237 |
| 79 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.95670430 |
| 80 | * TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.94727615 |
| 81 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.94322677 |
| 82 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.94045881 |
| 83 | * AR_25329375_ChIP-Seq_VCAP_Human | 0.94043177 |
| 84 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.93130116 |
| 85 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.92778121 |
| 86 | STAT3_23295773_ChIP-Seq_U87_Human | 0.91269981 |
| 87 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.88899588 |
| 88 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 0.88221656 |
| 89 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.88173356 |
| 90 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.88164190 |
| 91 | TCF4_23295773_ChIP-Seq_U87_Human | 0.86775562 |
| 92 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.86517999 |
| 93 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.85214095 |
| 94 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 0.84680608 |
| 95 | SOX9_26525672_Chip-Seq_HEART_Mouse | 0.83741708 |
| 96 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.83314249 |
| 97 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 0.81922921 |
| 98 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 0.81809992 |
| 99 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.80077984 |
| 100 | * P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.79574867 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0004859_abnormal_synaptic_plasticity | 6.07676027 |
| 2 | MP0003880_abnormal_central_pattern | 4.40184465 |
| 3 | MP0004270_analgesia | 4.24518203 |
| 4 | MP0005423_abnormal_somatic_nervous | 3.93454832 |
| 5 | MP0003635_abnormal_synaptic_transmissio | 3.86336310 |
| 6 | MP0002063_abnormal_learning/memory/cond | 3.14802817 |
| 7 | MP0002822_catalepsy | 3.14202460 |
| 8 | MP0009745_abnormal_behavioral_response | 3.06929939 |
| 9 | MP0002064_seizures | 3.03492723 |
| 10 | MP0002734_abnormal_mechanical_nocicepti | 2.95195753 |
| 11 | MP0002572_abnormal_emotion/affect_behav | 2.71522578 |
| 12 | MP0001968_abnormal_touch/_nociception | 2.71336170 |
| 13 | MP0002272_abnormal_nervous_system | 2.71309153 |
| 14 | MP0002735_abnormal_chemical_nociception | 2.68130777 |
| 15 | MP0009046_muscle_twitch | 2.64851384 |
| 16 | MP0000778_abnormal_nervous_system | 2.55960200 |
| 17 | MP0001486_abnormal_startle_reflex | 2.47810513 |
| 18 | MP0003122_maternal_imprinting | 2.40725303 |
| 19 | MP0002736_abnormal_nociception_after | 2.29451642 |
| 20 | MP0001970_abnormal_pain_threshold | 2.13721134 |
| 21 | MP0006276_abnormal_autonomic_nervous | 2.05620356 |
| 22 | MP0002733_abnormal_thermal_nociception | 2.05166384 |
| 23 | MP0003329_amyloid_beta_deposits | 2.03176818 |
| 24 | MP0003787_abnormal_imprinting | 1.99863236 |
| 25 | MP0001440_abnormal_grooming_behavior | 1.97105251 |
| 26 | MP0001984_abnormal_olfaction | 1.93832652 |
| 27 | MP0004811_abnormal_neuron_physiology | 1.92177252 |
| 28 | MP0002184_abnormal_innervation | 1.84420148 |
| 29 | MP0002557_abnormal_social/conspecific_i | 1.83486201 |
| 30 | MP0002067_abnormal_sensory_capabilities | 1.82278753 |
| 31 | MP0008569_lethality_at_weaning | 1.82104325 |
| 32 | MP0000955_abnormal_spinal_cord | 1.78480546 |
| 33 | MP0001501_abnormal_sleep_pattern | 1.76711651 |
| 34 | MP0001188_hyperpigmentation | 1.68784792 |
| 35 | MP0002882_abnormal_neuron_morphology | 1.66947717 |
| 36 | MP0005386_behavior/neurological_phenoty | 1.64252006 |
| 37 | MP0004924_abnormal_behavior | 1.64252006 |
| 38 | MP0002638_abnormal_pupillary_reflex | 1.60116491 |
| 39 | MP0004885_abnormal_endolymph | 1.59873104 |
| 40 | MP0001905_abnormal_dopamine_level | 1.55913036 |
| 41 | MP0003879_abnormal_hair_cell | 1.55081913 |
| 42 | MP0001529_abnormal_vocalization | 1.45506037 |
| 43 | MP0002066_abnormal_motor_capabilities/c | 1.45293809 |
| 44 | MP0001502_abnormal_circadian_rhythm | 1.42281139 |
| 45 | MP0003121_genomic_imprinting | 1.40811578 |
| 46 | MP0002909_abnormal_adrenal_gland | 1.40193132 |
| 47 | MP0004742_abnormal_vestibular_system | 1.37273771 |
| 48 | MP0002152_abnormal_brain_morphology | 1.32202287 |
| 49 | MP0003633_abnormal_nervous_system | 1.27168474 |
| 50 | MP0000569_abnormal_digit_pigmentation | 1.24803446 |
| 51 | MP0005646_abnormal_pituitary_gland | 1.18092259 |
| 52 | MP0003631_nervous_system_phenotype | 1.15525326 |
| 53 | MP0004142_abnormal_muscle_tone | 1.15480569 |
| 54 | MP0005645_abnormal_hypothalamus_physiol | 1.08931556 |
| 55 | MP0001177_atelectasis | 1.05531900 |
| 56 | MP0003123_paternal_imprinting | 1.05481958 |
| 57 | MP0010386_abnormal_urinary_bladder | 1.04245981 |
| 58 | MP0003634_abnormal_glial_cell | 0.99130382 |
| 59 | MP0002752_abnormal_somatic_nervous | 0.98331813 |
| 60 | MP0002229_neurodegeneration | 0.94524711 |
| 61 | MP0002069_abnormal_eating/drinking_beha | 0.93448747 |
| 62 | MP0003632_abnormal_nervous_system | 0.91176787 |
| 63 | MP0003861_abnormal_nervous_system | 0.90352386 |
| 64 | MP0003283_abnormal_digestive_organ | 0.87766220 |
| 65 | MP0003690_abnormal_glial_cell | 0.86334252 |
| 66 | MP0000631_abnormal_neuroendocrine_gland | 0.84284695 |
| 67 | MP0000920_abnormal_myelination | 0.84222621 |
| 68 | MP0008877_abnormal_DNA_methylation | 0.83935592 |
| 69 | MP0000604_amyloidosis | 0.83368501 |
| 70 | MP0005551_abnormal_eye_electrophysiolog | 0.83189766 |
| 71 | MP0001963_abnormal_hearing_physiology | 0.82864498 |
| 72 | MP0002751_abnormal_autonomic_nervous | 0.79339105 |
| 73 | MP0005187_abnormal_penis_morphology | 0.73830969 |
| 74 | MP0009780_abnormal_chondrocyte_physiolo | 0.71871438 |
| 75 | MP0010770_preweaning_lethality | 0.70296177 |
| 76 | MP0002082_postnatal_lethality | 0.70296177 |
| 77 | MP0000026_abnormal_inner_ear | 0.69742803 |
| 78 | MP0010769_abnormal_survival | 0.69733239 |
| 79 | MP0008872_abnormal_physiological_respon | 0.69316914 |
| 80 | MP0002102_abnormal_ear_morphology | 0.66699477 |
| 81 | MP0010768_mortality/aging | 0.66214287 |
| 82 | MP0001299_abnormal_eye_distance/ | 0.64585941 |
| 83 | MP0005409_darkened_coat_color | 0.64471908 |
| 84 | MP0003938_abnormal_ear_development | 0.63941280 |
| 85 | MP0005499_abnormal_olfactory_system | 0.62693694 |
| 86 | MP0005394_taste/olfaction_phenotype | 0.62693694 |
| 87 | MP0001943_abnormal_respiration | 0.62594699 |
| 88 | MP0002081_perinatal_lethality | 0.61395222 |
| 89 | MP0008874_decreased_physiological_sensi | 0.60524785 |
| 90 | MP0005535_abnormal_body_temperature | 0.58559659 |
| 91 | MP0000534_abnormal_ureter_morphology | 0.57523308 |
| 92 | MP0001485_abnormal_pinna_reflex | 0.54983248 |
| 93 | MP0004133_heterotaxia | 0.54391980 |
| 94 | MP0001986_abnormal_taste_sensitivity | 0.53169662 |
| 95 | MP0004145_abnormal_muscle_electrophysio | 0.51768498 |
| 96 | MP0003956_abnormal_body_size | 0.51146061 |
| 97 | MP0004130_abnormal_muscle_cell | 0.50908549 |
| 98 | MP0000579_abnormal_nail_morphology | 0.49349375 |
| 99 | MP0004085_abnormal_heartbeat | 0.49174863 |
| 100 | MP0003137_abnormal_impulse_conducting | 0.47322721 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Myokymia (HP:0002411) | 7.58094651 |
| 2 | Focal motor seizures (HP:0011153) | 7.23951570 |
| 3 | Focal seizures (HP:0007359) | 6.03608444 |
| 4 | Limb dystonia (HP:0002451) | 5.66488710 |
| 5 | Febrile seizures (HP:0002373) | 4.96997109 |
| 6 | Epileptic encephalopathy (HP:0200134) | 4.94841892 |
| 7 | Action tremor (HP:0002345) | 4.81766915 |
| 8 | Atonic seizures (HP:0010819) | 4.68576661 |
| 9 | Mutism (HP:0002300) | 4.06178340 |
| 10 | Generalized tonic-clonic seizures (HP:0002069) | 3.95894243 |
| 11 | Neurofibrillary tangles (HP:0002185) | 3.95173350 |
| 12 | Polyphagia (HP:0002591) | 3.92016831 |
| 13 | Supranuclear gaze palsy (HP:0000605) | 3.90927332 |
| 14 | Ankle clonus (HP:0011448) | 3.69023615 |
| 15 | Progressive cerebellar ataxia (HP:0002073) | 3.65769653 |
| 16 | Abnormality of binocular vision (HP:0011514) | 3.65425344 |
| 17 | Diplopia (HP:0000651) | 3.65425344 |
| 18 | Abnormal eating behavior (HP:0100738) | 3.60030010 |
| 19 | Dialeptic seizures (HP:0011146) | 3.47869106 |
| 20 | Drooling (HP:0002307) | 3.45099728 |
| 21 | Absence seizures (HP:0002121) | 3.40565769 |
| 22 | Torticollis (HP:0000473) | 3.36678719 |
| 23 | Akinesia (HP:0002304) | 3.33984144 |
| 24 | Abnormality of the corticospinal tract (HP:0002492) | 3.33738844 |
| 25 | Spastic gait (HP:0002064) | 3.24711019 |
| 26 | Excessive salivation (HP:0003781) | 3.21064190 |
| 27 | Cerebral inclusion bodies (HP:0100314) | 3.15661183 |
| 28 | Impaired vibration sensation in the lower limbs (HP:0002166) | 3.14060933 |
| 29 | Epileptiform EEG discharges (HP:0011182) | 3.13728402 |
| 30 | Urinary bladder sphincter dysfunction (HP:0002839) | 3.07274905 |
| 31 | Broad-based gait (HP:0002136) | 3.01888190 |
| 32 | Amyotrophic lateral sclerosis (HP:0007354) | 2.95470070 |
| 33 | EEG with generalized epileptiform discharges (HP:0011198) | 2.94176684 |
| 34 | Amblyopia (HP:0000646) | 2.93309570 |
| 35 | Urinary urgency (HP:0000012) | 2.92837539 |
| 36 | Truncal ataxia (HP:0002078) | 2.88526503 |
| 37 | Hypsarrhythmia (HP:0002521) | 2.85796758 |
| 38 | Hyperventilation (HP:0002883) | 2.83895153 |
| 39 | Focal dystonia (HP:0004373) | 2.70953423 |
| 40 | Morphological abnormality of the pyramidal tract (HP:0002062) | 2.66840731 |
| 41 | Hemiparesis (HP:0001269) | 2.63965977 |
| 42 | Postural instability (HP:0002172) | 2.61961454 |
| 43 | Sleep apnea (HP:0010535) | 2.59053910 |
| 44 | Dysmetria (HP:0001310) | 2.58822563 |
| 45 | Visual hallucinations (HP:0002367) | 2.55152440 |
| 46 | Craniofacial dystonia (HP:0012179) | 2.49115953 |
| 47 | Status epilepticus (HP:0002133) | 2.48344193 |
| 48 | Failure to thrive in infancy (HP:0001531) | 2.47803529 |
| 49 | Fetal akinesia sequence (HP:0001989) | 2.47066347 |
| 50 | Intention tremor (HP:0002080) | 2.45578693 |
| 51 | Abnormality of the lower motor neuron (HP:0002366) | 2.41165030 |
| 52 | Agitation (HP:0000713) | 2.40807202 |
| 53 | Poor eye contact (HP:0000817) | 2.37469878 |
| 54 | Hemiplegia (HP:0002301) | 2.37214681 |
| 55 | Anxiety (HP:0000739) | 2.37083861 |
| 56 | Lower limb muscle weakness (HP:0007340) | 2.36945244 |
| 57 | Depression (HP:0000716) | 2.36766481 |
| 58 | Papilledema (HP:0001085) | 2.32077357 |
| 59 | Absent speech (HP:0001344) | 2.31396594 |
| 60 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.30966895 |
| 61 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.30966895 |
| 62 | Gait imbalance (HP:0002141) | 2.29356845 |
| 63 | Dysdiadochokinesis (HP:0002075) | 2.28380951 |
| 64 | Megalencephaly (HP:0001355) | 2.27043838 |
| 65 | Apathy (HP:0000741) | 2.25568529 |
| 66 | Bradykinesia (HP:0002067) | 2.20575591 |
| 67 | Impaired social interactions (HP:0000735) | 2.18151814 |
| 68 | Abnormal social behavior (HP:0012433) | 2.18151814 |
| 69 | Pheochromocytoma (HP:0002666) | 2.17160302 |
| 70 | Hypoplasia of the brainstem (HP:0002365) | 2.16786433 |
| 71 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 2.16786433 |
| 72 | Neuronal loss in central nervous system (HP:0002529) | 2.14454617 |
| 73 | Spastic tetraplegia (HP:0002510) | 2.13267986 |
| 74 | Diminished motivation (HP:0000745) | 2.08236056 |
| 75 | Hypoplasia of the corpus callosum (HP:0002079) | 2.04696592 |
| 76 | Lissencephaly (HP:0001339) | 2.04477319 |
| 77 | Genetic anticipation (HP:0003743) | 2.02611007 |
| 78 | Esotropia (HP:0000565) | 1.99227741 |
| 79 | Inappropriate behavior (HP:0000719) | 1.96274694 |
| 80 | Peripheral hypomyelination (HP:0007182) | 1.95400408 |
| 81 | Poor suck (HP:0002033) | 1.94308248 |
| 82 | Pachygyria (HP:0001302) | 1.93594481 |
| 83 | Clonus (HP:0002169) | 1.92304850 |
| 84 | Abnormality of salivation (HP:0100755) | 1.91547180 |
| 85 | Spastic tetraparesis (HP:0001285) | 1.91459281 |
| 86 | Impaired vibratory sensation (HP:0002495) | 1.91251651 |
| 87 | Obstructive sleep apnea (HP:0002870) | 1.89848829 |
| 88 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 1.89472041 |
| 89 | Delusions (HP:0000746) | 1.86548483 |
| 90 | Impaired smooth pursuit (HP:0007772) | 1.86398784 |
| 91 | Insomnia (HP:0100785) | 1.86089831 |
| 92 | Hypoventilation (HP:0002791) | 1.85864183 |
| 93 | Annular pancreas (HP:0001734) | 1.85236262 |
| 94 | Specific learning disability (HP:0001328) | 1.84969023 |
| 95 | Cortical dysplasia (HP:0002539) | 1.84469248 |
| 96 | Incomplete penetrance (HP:0003829) | 1.83894311 |
| 97 | Exotropia (HP:0000577) | 1.83610780 |
| 98 | Gaze-evoked nystagmus (HP:0000640) | 1.81039903 |
| 99 | Neuroendocrine neoplasm (HP:0100634) | 1.80211393 |
| 100 | Muscular hypotonia of the trunk (HP:0008936) | 1.77141223 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MARK1 | 6.78631163 |
| 2 | CASK | 4.60926230 |
| 3 | EPHA4 | 3.47855684 |
| 4 | NTRK3 | 3.17614041 |
| 5 | NTRK2 | 3.02157769 |
| 6 | SIK2 | 2.84749993 |
| 7 | MAPK13 | 2.40031714 |
| 8 | PAK6 | 2.39727015 |
| 9 | MINK1 | 2.31343957 |
| 10 | NTRK1 | 2.25004703 |
| 11 | DAPK2 | 2.13978001 |
| 12 | MAP3K9 | 2.10649790 |
| 13 | DYRK2 | 1.96701966 |
| 14 | TNIK | 1.96220769 |
| 15 | MAP3K4 | 1.95265635 |
| 16 | UHMK1 | 1.91349841 |
| 17 | PHKG1 | 1.85827119 |
| 18 | PHKG2 | 1.85827119 |
| 19 | CAMKK1 | 1.84618640 |
| 20 | MAP2K7 | 1.71717744 |
| 21 | CDK5 | 1.57968741 |
| 22 | PRKD3 | 1.56244074 |
| 23 | PRKCG | 1.55061910 |
| 24 | LATS2 | 1.51897163 |
| 25 | CSNK1G2 | 1.28646744 |
| 26 | TYRO3 | 1.28599000 |
| 27 | PINK1 | 1.26110608 |
| 28 | CDK19 | 1.25938889 |
| 29 | BCR | 1.23288360 |
| 30 | PNCK | 1.21203642 |
| 31 | SGK223 | 1.20687955 |
| 32 | SGK494 | 1.20687955 |
| 33 | PLK2 | 1.19321397 |
| 34 | MAP2K4 | 1.14068089 |
| 35 | DYRK1A | 1.10780135 |
| 36 | PAK3 | 1.09469254 |
| 37 | CAMK2B | 1.05338639 |
| 38 | CAMKK2 | 1.03925090 |
| 39 | CDK18 | 1.02156746 |
| 40 | CDK15 | 1.01959592 |
| 41 | KSR1 | 1.01155758 |
| 42 | CAMK2A | 1.01044617 |
| 43 | CDK14 | 0.99974596 |
| 44 | PKN1 | 0.98112909 |
| 45 | CDK11A | 0.94314875 |
| 46 | WNK3 | 0.92850139 |
| 47 | SGK2 | 0.92562867 |
| 48 | MARK2 | 0.90179643 |
| 49 | GRK5 | 0.84342695 |
| 50 | DAPK1 | 0.82935901 |
| 51 | PRKCH | 0.81417392 |
| 52 | PRKCZ | 0.79402660 |
| 53 | CAMK1 | 0.76466233 |
| 54 | CSNK1G3 | 0.69126548 |
| 55 | STK11 | 0.64677499 |
| 56 | ARAF | 0.64202187 |
| 57 | SGK1 | 0.63116158 |
| 58 | MAPK12 | 0.62882188 |
| 59 | RIPK1 | 0.58873327 |
| 60 | ALK | 0.58317018 |
| 61 | SGK3 | 0.56707752 |
| 62 | PRKCE | 0.55543450 |
| 63 | EPHB2 | 0.55340075 |
| 64 | CSNK1A1L | 0.55125140 |
| 65 | MAP3K12 | 0.55047600 |
| 66 | CAMK4 | 0.51769411 |
| 67 | CAMK2G | 0.51130947 |
| 68 | KSR2 | 0.50582661 |
| 69 | OXSR1 | 0.47902758 |
| 70 | CSNK1G1 | 0.46173013 |
| 71 | FYN | 0.46064220 |
| 72 | RPS6KA3 | 0.45289653 |
| 73 | MAPK10 | 0.45080090 |
| 74 | ERBB3 | 0.44660586 |
| 75 | RET | 0.41697600 |
| 76 | CAMK1G | 0.41401090 |
| 77 | CCNB1 | 0.38790188 |
| 78 | CSNK1D | 0.38537694 |
| 79 | ROCK2 | 0.37757457 |
| 80 | CSNK1E | 0.36338822 |
| 81 | CAMK2D | 0.36188037 |
| 82 | TRIM28 | 0.35987452 |
| 83 | RPS6KB1 | 0.35814453 |
| 84 | RPS6KA2 | 0.35675399 |
| 85 | LIMK1 | 0.33902622 |
| 86 | TESK1 | 0.33706359 |
| 87 | PRKG1 | 0.33631193 |
| 88 | PRKACA | 0.30984545 |
| 89 | FES | 0.30458154 |
| 90 | ERBB2 | 0.30287970 |
| 91 | EPHA3 | 0.30013448 |
| 92 | STK38 | 0.29600371 |
| 93 | DYRK1B | 0.29334393 |
| 94 | MAPK8 | 0.29225377 |
| 95 | PRKCA | 0.25709933 |
| 96 | PRKCB | 0.24593374 |
| 97 | GSK3B | 0.24284253 |
| 98 | MAPK9 | 0.23736454 |
| 99 | MAPK4 | 0.23654171 |
| 100 | NEK6 | 0.23469241 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Nicotine addiction_Homo sapiens_hsa05033 | 4.87697742 |
| 2 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.47544791 |
| 3 | GABAergic synapse_Homo sapiens_hsa04727 | 2.98764281 |
| 4 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.87204234 |
| 5 | Circadian entrainment_Homo sapiens_hsa04713 | 2.87010898 |
| 6 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.85866593 |
| 7 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.82447063 |
| 8 | Morphine addiction_Homo sapiens_hsa05032 | 2.71655484 |
| 9 | Long-term potentiation_Homo sapiens_hsa04720 | 2.61966477 |
| 10 | Cocaine addiction_Homo sapiens_hsa05030 | 2.61372353 |
| 11 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.52533784 |
| 12 | Insulin secretion_Homo sapiens_hsa04911 | 2.09010184 |
| 13 | Cholinergic synapse_Homo sapiens_hsa04725 | 2.08854522 |
| 14 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.94260847 |
| 15 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.94168308 |
| 16 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.75243804 |
| 17 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.68751257 |
| 18 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.64478350 |
| 19 | Axon guidance_Homo sapiens_hsa04360 | 1.62257541 |
| 20 | Taste transduction_Homo sapiens_hsa04742 | 1.58199744 |
| 21 | Long-term depression_Homo sapiens_hsa04730 | 1.57035581 |
| 22 | Salivary secretion_Homo sapiens_hsa04970 | 1.53415915 |
| 23 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.50094238 |
| 24 | Gap junction_Homo sapiens_hsa04540 | 1.44231079 |
| 25 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.40499926 |
| 26 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.38127970 |
| 27 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 1.31800682 |
| 28 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.31561817 |
| 29 | Renin secretion_Homo sapiens_hsa04924 | 1.29960564 |
| 30 | Phototransduction_Homo sapiens_hsa04744 | 1.28668920 |
| 31 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.23136918 |
| 32 | Olfactory transduction_Homo sapiens_hsa04740 | 1.20497057 |
| 33 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.20487975 |
| 34 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.15895537 |
| 35 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.14777277 |
| 36 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.13593414 |
| 37 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.09852107 |
| 38 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.06880452 |
| 39 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.06759034 |
| 40 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.05358724 |
| 41 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.04011759 |
| 42 | Melanogenesis_Homo sapiens_hsa04916 | 1.03397317 |
| 43 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.01854954 |
| 44 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.84490021 |
| 45 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.84413284 |
| 46 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.84181790 |
| 47 | Glioma_Homo sapiens_hsa05214 | 0.83104427 |
| 48 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.80116426 |
| 49 | Alcoholism_Homo sapiens_hsa05034 | 0.78253510 |
| 50 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.75818094 |
| 51 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.75284355 |
| 52 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.74003524 |
| 53 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.72237459 |
| 54 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.71668632 |
| 55 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.71461953 |
| 56 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.70615956 |
| 57 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.70610742 |
| 58 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.70071370 |
| 59 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.66775996 |
| 60 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.65114262 |
| 61 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.65023811 |
| 62 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.64526892 |
| 63 | Prion diseases_Homo sapiens_hsa05020 | 0.63984511 |
| 64 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.59004906 |
| 65 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.58910075 |
| 66 | Bile secretion_Homo sapiens_hsa04976 | 0.58270303 |
| 67 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.57541935 |
| 68 | Alzheimers disease_Homo sapiens_hsa05010 | 0.57327277 |
| 69 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.57311572 |
| 70 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.56538878 |
| 71 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.52137180 |
| 72 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.50443247 |
| 73 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.49858728 |
| 74 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.46240352 |
| 75 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.43840571 |
| 76 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.43680607 |
| 77 | Endometrial cancer_Homo sapiens_hsa05213 | 0.43445196 |
| 78 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.43412534 |
| 79 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.42961705 |
| 80 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.42441084 |
| 81 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.40654065 |
| 82 | Circadian rhythm_Homo sapiens_hsa04710 | 0.38965266 |
| 83 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.36470861 |
| 84 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.35625789 |
| 85 | Endocytosis_Homo sapiens_hsa04144 | 0.34757741 |
| 86 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.34518207 |
| 87 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.32511933 |
| 88 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.32348978 |
| 89 | Tight junction_Homo sapiens_hsa04530 | 0.32203720 |
| 90 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.32132074 |
| 91 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.31343067 |
| 92 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.30447065 |
| 93 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.29301823 |
| 94 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.29135639 |
| 95 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.28677276 |
| 96 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.27817268 |
| 97 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.27592340 |
| 98 | Parkinsons disease_Homo sapiens_hsa05012 | 0.26970631 |
| 99 | Colorectal cancer_Homo sapiens_hsa05210 | 0.25689643 |
| 100 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.24957303 |

