HN1L

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)5.22249492
2DNA strand elongation involved in DNA replication (GO:0006271)4.85723585
3DNA replication initiation (GO:0006270)4.69614572
4DNA strand elongation (GO:0022616)4.62321062
5telomere maintenance via semi-conservative replication (GO:0032201)4.45723085
6folic acid-containing compound biosynthetic process (GO:0009396)4.45411278
7DNA replication-dependent nucleosome organization (GO:0034723)4.17459295
8DNA replication-dependent nucleosome assembly (GO:0006335)4.17459295
9telomere maintenance via recombination (GO:0000722)4.09374288
10nucleobase biosynthetic process (GO:0046112)4.08845300
11IMP biosynthetic process (GO:0006188)4.06376353
12protein localization to kinetochore (GO:0034501)4.01619118
13DNA replication checkpoint (GO:0000076)3.99558907
14nuclear pore organization (GO:0006999)3.99342065
15mitotic recombination (GO:0006312)3.94342390
16mitotic nuclear envelope disassembly (GO:0007077)3.88615357
17regulation of translational fidelity (GO:0006450)3.85526297
18protein complex localization (GO:0031503)3.80749561
19nuclear pore complex assembly (GO:0051292)3.75480677
20mitotic metaphase plate congression (GO:0007080)3.71870619
21purine nucleobase biosynthetic process (GO:0009113)3.69323781
22telomere maintenance via telomere lengthening (GO:0010833)3.63952843
23chromatin remodeling at centromere (GO:0031055)3.61425592
24formation of translation preinitiation complex (GO:0001731)3.60761314
25nuclear envelope disassembly (GO:0051081)3.58385261
26membrane disassembly (GO:0030397)3.58385261
27nucleotide-excision repair, DNA gap filling (GO:0006297)3.57855475
28CENP-A containing nucleosome assembly (GO:0034080)3.57447128
29IMP metabolic process (GO:0046040)3.53838487
30DNA geometric change (GO:0032392)3.43998747
31DNA duplex unwinding (GO:0032508)3.43737939
32metaphase plate congression (GO:0051310)3.42041638
33mitotic chromosome condensation (GO:0007076)3.41860214
34Golgi transport vesicle coating (GO:0048200)3.40743741
35COPI coating of Golgi vesicle (GO:0048205)3.40743741
36proline biosynthetic process (GO:0006561)3.39977085
37DNA replication-independent nucleosome organization (GO:0034724)3.39188339
38DNA replication-independent nucleosome assembly (GO:0006336)3.39188339
39regulation of nuclear cell cycle DNA replication (GO:0033262)3.39130075
40somatic diversification of immune receptors via somatic mutation (GO:0002566)3.35648948
41somatic hypermutation of immunoglobulin genes (GO:0016446)3.35648948
42protein localization to chromosome, centromeric region (GO:0071459)3.32539687
43cellular protein complex localization (GO:0034629)3.32436329
44kinetochore organization (GO:0051383)3.31726275
45mismatch repair (GO:0006298)3.27769958
46regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.26469714
47regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.26396554
48establishment of apical/basal cell polarity (GO:0035089)3.22926363
49negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.19214114
50attachment of spindle microtubules to kinetochore (GO:0008608)3.18966146
51chromosome condensation (GO:0030261)3.18444741
52L-serine metabolic process (GO:0006563)3.17400057
53heterochromatin organization (GO:0070828)3.12683073
54establishment of chromosome localization (GO:0051303)3.11635790
55regulation of helicase activity (GO:0051095)3.10921722
56ribosome assembly (GO:0042255)3.09014060
57pteridine-containing compound biosynthetic process (GO:0042559)3.08645108
58mitotic sister chromatid segregation (GO:0000070)3.08423582
59negative regulation of chromosome segregation (GO:0051985)3.06626307
60planar cell polarity pathway involved in neural tube closure (GO:0090179)3.05762995
61negative regulation of mitotic sister chromatid separation (GO:2000816)3.05529615
62negative regulation of mitotic sister chromatid segregation (GO:0033048)3.05529615
63negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.05529615
64negative regulation of sister chromatid segregation (GO:0033046)3.05529615
65translesion synthesis (GO:0019985)3.03054052
66spindle assembly checkpoint (GO:0071173)3.03037160
67regulation of centriole replication (GO:0046599)3.01308527
68nucleobase-containing small molecule interconversion (GO:0015949)3.00114036
69mitotic spindle assembly checkpoint (GO:0007094)2.99951420
70sister chromatid segregation (GO:0000819)2.99779228
71kinetochore assembly (GO:0051382)2.98822717
72histone exchange (GO:0043486)2.97990889
73negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.97758143
74spindle checkpoint (GO:0031577)2.97488234
75DNA topological change (GO:0006265)2.97485674
76dosage compensation (GO:0007549)2.97132469
77establishment of integrated proviral latency (GO:0075713)2.95792293
78chromatin assembly or disassembly (GO:0006333)2.95728821
79telomere maintenance (GO:0000723)2.95680212
80base-excision repair (GO:0006284)2.94689966
81telomere organization (GO:0032200)2.94614964
82establishment of viral latency (GO:0019043)2.92775689
83deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.92387629
84mitotic sister chromatid cohesion (GO:0007064)2.92175597
85regulation of mitotic metaphase/anaphase transition (GO:0030071)2.91632609
86regulation of centrosome cycle (GO:0046605)2.91512479
87paraxial mesoderm development (GO:0048339)2.91459738
88axonemal dynein complex assembly (GO:0070286)2.90129563
89regulation of spindle organization (GO:0090224)2.89427970
90negative regulation of RNA splicing (GO:0033119)2.89332657
91pore complex assembly (GO:0046931)2.88995996
92mitotic spindle checkpoint (GO:0071174)2.88873935
93regulation of posttranscriptional gene silencing (GO:0060147)2.88154130
94regulation of gene silencing by miRNA (GO:0060964)2.88154130
95regulation of gene silencing by RNA (GO:0060966)2.88154130
96intra-S DNA damage checkpoint (GO:0031573)2.87858556
97regulation of double-strand break repair via homologous recombination (GO:0010569)2.87823015
98regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.85943221
99regulation of chromosome segregation (GO:0051983)2.85347185
100DNA conformation change (GO:0071103)2.84754911
101transcription-coupled nucleotide-excision repair (GO:0006283)2.81944780
102notochord development (GO:0030903)2.81840475
103postreplication repair (GO:0006301)2.81534904
104meiotic chromosome segregation (GO:0045132)2.80168974
105ribosomal small subunit assembly (GO:0000028)2.79202001
106regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.78996151
107negative regulation of mRNA processing (GO:0050686)2.78929303
108desmosome organization (GO:0002934)2.78517791
109regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.77401957
110tetrahydrofolate metabolic process (GO:0046653)2.77390875
111ribosome biogenesis (GO:0042254)2.77014028
112pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)2.75796226
113nuclear envelope organization (GO:0006998)2.75639845
114DNA packaging (GO:0006323)2.74668993
115regulation of sister chromatid cohesion (GO:0007063)2.74406699
116viral mRNA export from host cell nucleus (GO:0046784)2.74225494
117deoxyribonucleotide biosynthetic process (GO:0009263)2.73262171
118ribosomal small subunit biogenesis (GO:0042274)2.72746534
119regulation of translational termination (GO:0006449)2.71185822
120positive regulation of chromosome segregation (GO:0051984)2.69974009
121pre-miRNA processing (GO:0031054)2.68123681
122nucleosome disassembly (GO:0006337)2.65865397
123protein-DNA complex disassembly (GO:0032986)2.65865397
124regulation of mitotic spindle organization (GO:0060236)2.65197150
125maturation of SSU-rRNA (GO:0030490)2.63979046
126spliceosomal tri-snRNP complex assembly (GO:0000244)2.62999378
127negative regulation of mRNA metabolic process (GO:1903312)2.62938078
128establishment of monopolar cell polarity (GO:0061162)2.61117020
129establishment or maintenance of monopolar cell polarity (GO:0061339)2.61117020
130peptidyl-arginine omega-N-methylation (GO:0035247)2.60052678
131double-strand break repair via nonhomologous end joining (GO:0006303)2.59516564
132non-recombinational repair (GO:0000726)2.59516564
133ATP-dependent chromatin remodeling (GO:0043044)2.56294686
134maternal placenta development (GO:0001893)2.55483966
135regulation of RNA export from nucleus (GO:0046831)2.52913514
136serine family amino acid biosynthetic process (GO:0009070)2.52633244
137regulation of mammary gland epithelial cell proliferation (GO:0033599)2.51991376
138protein export from nucleus (GO:0006611)2.50827254
139histone arginine methylation (GO:0034969)2.48596437
140RNA stabilization (GO:0043489)2.40444418
141mRNA stabilization (GO:0048255)2.40444418
142ribonucleoprotein complex biogenesis (GO:0022613)2.37351872
143negative regulation of DNA repair (GO:0045738)2.37339914
144epithelial cell-cell adhesion (GO:0090136)2.37186646
145hippo signaling (GO:0035329)2.36713704
146DNA synthesis involved in DNA repair (GO:0000731)2.36634568
147protein localization to microtubule (GO:0035372)2.34699415
148convergent extension (GO:0060026)2.34601292

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.86018427
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.15642251
3FOXM1_23109430_ChIP-Seq_U2OS_Human4.02127942
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.77915030
5FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.30002229
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.18633590
7KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.02797722
8* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.79166845
9MYC_19079543_ChIP-ChIP_MESCs_Mouse2.78331355
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.66470459
11TP63_17297297_ChIP-ChIP_HaCaT_Human2.65678214
12MYC_18358816_ChIP-ChIP_MESCs_Mouse2.61927969
13GABP_17652178_ChIP-ChIP_JURKAT_Human2.52530879
14NELFA_20434984_ChIP-Seq_ESCs_Mouse2.51676197
15JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.41093077
16ETS1_20019798_ChIP-Seq_JURKAT_Human2.32451259
17ZNF263_19887448_ChIP-Seq_K562_Human2.29377514
18CREB1_15753290_ChIP-ChIP_HEK293T_Human2.28539106
19E2F1_21310950_ChIP-Seq_MCF-7_Human2.25847274
20AR_21909140_ChIP-Seq_LNCAP_Human2.25520485
21EGR1_19374776_ChIP-ChIP_THP-1_Human2.25448216
22CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.25389439
23HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.23288589
24* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.19954325
25ELF1_17652178_ChIP-ChIP_JURKAT_Human2.16543012
26XRN2_22483619_ChIP-Seq_HELA_Human2.15633861
27NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.14054147
28MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.11010125
29* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.06138508
30TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.05290163
31PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.99872776
32MYCN_18555785_ChIP-Seq_MESCs_Mouse1.99384903
33MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.98978843
34ESR1_15608294_ChIP-ChIP_MCF-7_Human1.97616439
35VDR_23849224_ChIP-Seq_CD4+_Human1.95671941
36DCP1A_22483619_ChIP-Seq_HELA_Human1.89547124
37GABP_19822575_ChIP-Seq_HepG2_Human1.83534697
38FOXP3_21729870_ChIP-Seq_TREG_Human1.81260452
39SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.74786813
40TTF2_22483619_ChIP-Seq_HELA_Human1.73202845
41ZFX_18555785_ChIP-Seq_MESCs_Mouse1.73147758
42ELK1_19687146_ChIP-ChIP_HELA_Human1.70242047
43NANOG_18555785_ChIP-Seq_MESCs_Mouse1.68699300
44CIITA_25753668_ChIP-Seq_RAJI_Human1.68401801
45YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.65602291
46CLOCK_20551151_ChIP-Seq_293T_Human1.64247764
47THAP11_20581084_ChIP-Seq_MESCs_Mouse1.61835029
48POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.61025816
49FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.59795550
50TP63_19390658_ChIP-ChIP_HaCaT_Human1.56080005
51FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.53534114
52* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.52206277
53SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.50578149
54RBPJ_22232070_ChIP-Seq_NCS_Mouse1.49954054
55NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.48217429
56TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.47905086
57MYC_22102868_ChIP-Seq_BL_Human1.47520718
58CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.46499868
59* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.44801662
60KDM5A_27292631_Chip-Seq_BREAST_Human1.44536719
61HOXB4_20404135_ChIP-ChIP_EML_Mouse1.42598914
62POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.38209137
63* RACK7_27058665_Chip-Seq_MCF-7_Human1.38140507
64* TFEB_21752829_ChIP-Seq_HELA_Human1.37465463
65SOX2_18555785_ChIP-Seq_MESCs_Mouse1.37011206
66ERG_20887958_ChIP-Seq_HPC-7_Mouse1.36402455
67SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.35760182
68DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.35514867
69ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.34486210
70TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.29737673
71PADI4_21655091_ChIP-ChIP_MCF-7_Human1.27369287
72* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.26471818
73PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.26035391
74HIF1A_21447827_ChIP-Seq_MCF-7_Human1.25812659
75MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.24422205
76POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.23130568
77ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.22959219
78HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.22858189
79HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.21532495
80SRF_21415370_ChIP-Seq_HL-1_Mouse1.21333245
81* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.16257645
82KLF4_18555785_ChIP-Seq_MESCs_Mouse1.15409732
83YY1_21170310_ChIP-Seq_MESCs_Mouse1.14482369
84SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.14408241
85PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.12550556
86CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.12540908
87ATF3_27146783_Chip-Seq_COLON_Human1.12485364
88KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.12258765
89CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.09281758
90SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.08410373
91SALL1_21062744_ChIP-ChIP_HESCs_Human1.07766469
92ESR1_21235772_ChIP-Seq_MCF-7_Human1.07419994
93DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.05721542
94TCF3_18692474_ChIP-Seq_MEFs_Mouse1.05544799
95* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.03555267
96KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.02506807
97KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.02506807
98KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.02506807
99STAT3_1855785_ChIP-Seq_MESCs_Mouse1.01313709
100* TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse1.00728539
101EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.99740715
102GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.99174654
103HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.98272574
104NANOG_21062744_ChIP-ChIP_HESCs_Human0.97634512
105FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.96254950
106TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.95759526
107ESR2_21235772_ChIP-Seq_MCF-7_Human0.95067722
108SOX2_18692474_ChIP-Seq_MEFs_Mouse0.94214803
109TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.94038571
110ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.93529388
111GATA6_25053715_ChIP-Seq_YYC3_Human0.92802977
112CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.92281248
113P300_27058665_Chip-Seq_ZR-75-30cells_Human0.92225881
114ZFP281_18757296_ChIP-ChIP_E14_Mouse0.90203916
115* SOX2_27498859_Chip-Seq_STOMACH_Mouse0.89501387
116SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.89302278
117TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.88939364
118MYC_18940864_ChIP-ChIP_HL60_Human0.88814988
119NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.88479523
120OCT4_18692474_ChIP-Seq_MEFs_Mouse0.88073911
121* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.87340868
122RUNX1_27514584_Chip-Seq_MCF-7_Human0.86895035
123BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.86486745
124STAT6_21828071_ChIP-Seq_BEAS2B_Human0.86298854
125TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.86183245
126NANOG_16153702_ChIP-ChIP_HESCs_Human0.85910428
127SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.85692737
128KAP1_27257070_Chip-Seq_ESCs_Mouse0.84795541
129SOX17_20123909_ChIP-Seq_XEN_Mouse0.84689964
130WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.84478141
131ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.82648970
132KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.81474426
133NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.81052345
134TCF3_18692474_ChIP-Seq_MESCs_Mouse0.80333794
135CHD1_26751641_Chip-Seq_LNCaP_Human0.79703364

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.53839189
2MP0010094_abnormal_chromosome_stability4.00679753
3MP0003111_abnormal_nucleus_morphology3.75214315
4MP0004957_abnormal_blastocyst_morpholog3.74698053
5MP0003077_abnormal_cell_cycle3.47512620
6MP0008057_abnormal_DNA_replication3.45926061
7MP0008058_abnormal_DNA_repair2.93563390
8MP0010234_abnormal_vibrissa_follicle2.82245122
9MP0008007_abnormal_cellular_replicative2.65522412
10MP0003123_paternal_imprinting2.52795283
11MP0008932_abnormal_embryonic_tissue2.51688762
12MP0010352_gastrointestinal_tract_polyps2.33210053
13MP0010030_abnormal_orbit_morphology2.24546240
14MP0003890_abnormal_embryonic-extraembry2.17612221
15MP0001730_embryonic_growth_arrest2.04509125
16MP0000350_abnormal_cell_proliferation2.00805288
17MP0002796_impaired_skin_barrier1.93475399
18MP0003121_genomic_imprinting1.91311166
19MP0008877_abnormal_DNA_methylation1.80676504
20MP0000579_abnormal_nail_morphology1.79723279
21MP0004264_abnormal_extraembryonic_tissu1.74241906
22MP0006292_abnormal_olfactory_placode1.69110179
23MP0005380_embryogenesis_phenotype1.68901928
24MP0001672_abnormal_embryogenesis/_devel1.68901928
25MP0001697_abnormal_embryo_size1.68821988
26MP0002084_abnormal_developmental_patter1.65361131
27MP0002085_abnormal_embryonic_tissue1.64521122
28MP0004233_abnormal_muscle_weight1.61854974
29MP0001346_abnormal_lacrimal_gland1.61374185
30MP0010307_abnormal_tumor_latency1.58774693
31MP0002396_abnormal_hematopoietic_system1.58658728
32MP0001293_anophthalmia1.56575104
33MP0005501_abnormal_skin_physiology1.56495849
34MP0004133_heterotaxia1.56459274
35MP0000490_abnormal_crypts_of1.56192100
36MP0003283_abnormal_digestive_organ1.53630683
37MP0003984_embryonic_growth_retardation1.51652243
38MP0004197_abnormal_fetal_growth/weight/1.50197358
39MP0003119_abnormal_digestive_system1.48495611
40MP0005623_abnormal_meninges_morphology1.47843280
41MP0004272_abnormal_basement_membrane1.47798458
42MP0002088_abnormal_embryonic_growth/wei1.47761844
43MP0002080_prenatal_lethality1.45883081
44MP0009053_abnormal_anal_canal1.45233877
45MP0000537_abnormal_urethra_morphology1.43991244
46MP0004185_abnormal_adipocyte_glucose1.43920186
47MP0000678_abnormal_parathyroid_gland1.43891313
48MP0002877_abnormal_melanocyte_morpholog1.38442806
49MP0002086_abnormal_extraembryonic_tissu1.37690698
50MP0006054_spinal_hemorrhage1.33175784
51MP0005076_abnormal_cell_differentiation1.31264800
52MP0000762_abnormal_tongue_morphology1.30907815
53MP0003786_premature_aging1.28508062
54MP0003567_abnormal_fetal_cardiomyocyte1.28238425
55MP0003937_abnormal_limbs/digits/tail_de1.25111947
56MP0002938_white_spotting1.24628194
57MP0000313_abnormal_cell_death1.24511868
58MP0010678_abnormal_skin_adnexa1.24352135
59MP0000566_synostosis1.23625617
60MP0005248_abnormal_Harderian_gland1.17820089
61MP0005220_abnormal_exocrine_pancreas1.16835703
62MP0003453_abnormal_keratinocyte_physiol1.15703698
63MP0002111_abnormal_tail_morphology1.13548221
64MP0002019_abnormal_tumor_incidence1.13151760
65MP0009672_abnormal_birth_weight1.13054534
66MP0004858_abnormal_nervous_system1.12053828
67MP0003941_abnormal_skin_development1.11676846
68MP0004808_abnormal_hematopoietic_stem1.11614092
69MP0000627_abnormal_mammary_gland1.08142719
70MP0003315_abnormal_perineum_morphology1.07533151
71MP0003806_abnormal_nucleotide_metabolis1.06269902
72MP0002653_abnormal_ependyma_morphology1.04178052
73MP0000428_abnormal_craniofacial_morphol1.03581986
74MP0009780_abnormal_chondrocyte_physiolo1.03089266
75MP0003122_maternal_imprinting1.02593010
76MP0004782_abnormal_surfactant_physiolog1.02527322
77MP0002249_abnormal_larynx_morphology1.01180017
78MP0002233_abnormal_nose_morphology1.00540768
79MP0000467_abnormal_esophagus_morphology1.00311813
80MP0003718_maternal_effect1.00095388
81MP0009703_decreased_birth_body1.00044629
82MP0000049_abnormal_middle_ear0.96847271
83MP0002060_abnormal_skin_morphology0.96079379
84MP0001216_abnormal_epidermal_layer0.96037450
85MP0000377_abnormal_hair_follicle0.94385994
86MP0003861_abnormal_nervous_system0.94281034
87MP0009379_abnormal_foot_pigmentation0.93113221
88MP0000383_abnormal_hair_follicle0.93109133
89MP0001881_abnormal_mammary_gland0.92899086
90MP0001661_extended_life_span0.92255248
91MP0002210_abnormal_sex_determination0.91776642
92MP0002160_abnormal_reproductive_system0.87724965
93MP0001286_abnormal_eye_development0.87524044
94MP0001145_abnormal_male_reproductive0.86697103
95MP0000534_abnormal_ureter_morphology0.86426798
96MP0000432_abnormal_head_morphology0.84494712
97MP0002092_abnormal_eye_morphology0.84295405
98MP0001915_intracranial_hemorrhage0.84248073
99MP0002697_abnormal_eye_size0.83649456
100MP0003935_abnormal_craniofacial_develop0.83227920
101MP0009697_abnormal_copulation0.82698596
102MP0001727_abnormal_embryo_implantation0.80625367
103MP0005023_abnormal_wound_healing0.80410377
104MP0002089_abnormal_postnatal_growth/wei0.80242928
105MP0005384_cellular_phenotype0.79124330
106MP0002932_abnormal_joint_morphology0.79082669
107MP0002254_reproductive_system_inflammat0.79007378
108MP0003755_abnormal_palate_morphology0.78003472
109MP0001849_ear_inflammation0.77169412
110MP0005389_reproductive_system_phenotype0.75927260
111MP0003942_abnormal_urinary_system0.75834010
112MP0003385_abnormal_body_wall0.75539151
113MP0000653_abnormal_sex_gland0.74544860
114MP0005257_abnormal_intraocular_pressure0.74472708
115MP0000358_abnormal_cell_content/0.74208781
116MP0001119_abnormal_female_reproductive0.74049928
117MP0005409_darkened_coat_color0.73997788
118MP0005083_abnormal_biliary_tract0.73938153
119MP0005451_abnormal_body_composition0.73462579
120MP0001944_abnormal_pancreas_morphology0.72383652
121MP0003566_abnormal_cell_adhesion0.71520721
122MP0006072_abnormal_retinal_apoptosis0.70627791
123MP0002177_abnormal_outer_ear0.70597696
124MP0002098_abnormal_vibrissa_morphology0.70566024
125MP0000462_abnormal_digestive_system0.70288390
126MP0005621_abnormal_cell_physiology0.69622160
127MP0002075_abnormal_coat/hair_pigmentati0.69590131
128MP0001186_pigmentation_phenotype0.69059661
129MP0002116_abnormal_craniofacial_bone0.68665247
130MP0000477_abnormal_intestine_morphology0.68601291
131MP0001929_abnormal_gametogenesis0.67612393
132MP0003705_abnormal_hypodermis_morpholog0.67230763
133MP0000858_altered_metastatic_potential0.64065013
134MP0005408_hypopigmentation0.63431603
135MP0003115_abnormal_respiratory_system0.61590027
136MP0002114_abnormal_axial_skeleton0.61432408

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.54012723
2Chromsome breakage (HP:0040012)3.64818801
3Colon cancer (HP:0003003)3.52997757
4Medulloblastoma (HP:0002885)3.47887406
5Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.47706453
6Chromosomal breakage induced by crosslinking agents (HP:0003221)3.45952840
7Ependymoma (HP:0002888)3.23886795
8Degeneration of anterior horn cells (HP:0002398)3.21423045
9Abnormality of the anterior horn cell (HP:0006802)3.21423045
10Chronic bronchitis (HP:0004469)3.17852210
11Aplastic anemia (HP:0001915)3.06383788
12Breast hypoplasia (HP:0003187)3.04022435
13Agnosia (HP:0010524)2.95691366
14Selective tooth agenesis (HP:0001592)2.87017985
15Abnormality of chromosome stability (HP:0003220)2.83278394
16Meckel diverticulum (HP:0002245)2.81849571
17Abnormality of the ileum (HP:0001549)2.76732653
18Patellar aplasia (HP:0006443)2.76348292
19Aplasia/Hypoplasia of the uvula (HP:0010293)2.70134412
20Oral leukoplakia (HP:0002745)2.68590306
21Abnormal respiratory motile cilium physiology (HP:0012261)2.62960109
22Hyperacusis (HP:0010780)2.62452388
23Reticulocytopenia (HP:0001896)2.61997211
24Rhinitis (HP:0012384)2.60696533
25Aplasia/Hypoplasia of the patella (HP:0006498)2.58811042
26Abnormal lung lobation (HP:0002101)2.55720128
27Intestinal atresia (HP:0011100)2.55533292
28Volvulus (HP:0002580)2.45684492
29Rhabdomyosarcoma (HP:0002859)2.45071374
30Neoplasm of the oral cavity (HP:0100649)2.44683232
31Flat acetabular roof (HP:0003180)2.43216557
32Abnormality of the preputium (HP:0100587)2.43052945
33Ectopic kidney (HP:0000086)2.39524987
34Asymmetry of the thorax (HP:0001555)2.39106299
35Duodenal stenosis (HP:0100867)2.35418192
36Small intestinal stenosis (HP:0012848)2.35418192
37Myelodysplasia (HP:0002863)2.34875895
38Increased nuchal translucency (HP:0010880)2.34386201
3911 pairs of ribs (HP:0000878)2.33241622
40Atresia of the external auditory canal (HP:0000413)2.25882096
41Septate vagina (HP:0001153)2.25802545
42Neoplasm of the pancreas (HP:0002894)2.25335069
43Type I transferrin isoform profile (HP:0003642)2.25292905
44Ankyloglossia (HP:0010296)2.25178007
45Short 4th metacarpal (HP:0010044)2.24127008
46Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.24127008
47Abnormality of the duodenum (HP:0002246)2.20711599
48Glioma (HP:0009733)2.20572601
49Carpal bone hypoplasia (HP:0001498)2.19687894
50Abnormal ciliary motility (HP:0012262)2.18794988
51Abnormal respiratory motile cilium morphology (HP:0005938)2.17791134
52Abnormal respiratory epithelium morphology (HP:0012253)2.17791134
53Multiple enchondromatosis (HP:0005701)2.16467914
54Short nail (HP:0001799)2.16392426
55Facial hemangioma (HP:0000329)2.15805687
56Abnormality of the metopic suture (HP:0005556)2.14081511
57Supernumerary spleens (HP:0009799)2.12395215
58Overlapping toe (HP:0001845)2.12283914
59Abnormality of the distal phalanges of the toes (HP:0010182)2.11779963
60Slender long bone (HP:0003100)2.11219081
61Nephroblastoma (Wilms tumor) (HP:0002667)2.10770416
62Missing ribs (HP:0000921)2.10646861
63Microretrognathia (HP:0000308)2.09054970
64Termporal pattern (HP:0011008)2.08817673
65Insidious onset (HP:0003587)2.08817673
66Sloping forehead (HP:0000340)2.07530099
67Premature graying of hair (HP:0002216)2.06700459
68Abnormal number of incisors (HP:0011064)2.05969166
69Spastic diplegia (HP:0001264)2.05957347
70Absent radius (HP:0003974)2.05373769
71Deviation of the thumb (HP:0009603)2.05066932
72Pterygium (HP:0001059)2.04690273
73Rough bone trabeculation (HP:0100670)2.04645786
74Proximal placement of thumb (HP:0009623)2.02860561
75Abnormality of the carotid arteries (HP:0005344)2.01405244
76Astrocytoma (HP:0009592)2.00852594
77Abnormality of the astrocytes (HP:0100707)2.00852594
78High anterior hairline (HP:0009890)2.00769569
79Abnormality of the umbilical cord (HP:0010881)2.00765560
80Abnormality of the distal phalanx of the thumb (HP:0009617)2.00739112
81Spinal muscular atrophy (HP:0007269)1.99768167
82Hypoplastic labia majora (HP:0000059)1.99641173
83Bifid tongue (HP:0010297)1.99157966
84Prominent metopic ridge (HP:0005487)1.97446240
85Rib fusion (HP:0000902)1.97365029
86Optic nerve coloboma (HP:0000588)1.97268413
87Ulnar bowing (HP:0003031)1.97071848
88Hypoplasia of the capital femoral epiphysis (HP:0003090)1.96834754
89Impulsivity (HP:0100710)1.95414021
90Neoplasm of the colon (HP:0100273)1.95141168
91Overriding aorta (HP:0002623)1.94261290
92Embryonal renal neoplasm (HP:0011794)1.94118526
93Facial cleft (HP:0002006)1.93583880
94Microglossia (HP:0000171)1.92406220
95Duplication of thumb phalanx (HP:0009942)1.92229822
96Right ventricular cardiomyopathy (HP:0011663)1.91330748
97Renal duplication (HP:0000075)1.90891443
98Aplasia/Hypoplasia of the sternum (HP:0006714)1.90141499
99Pili torti (HP:0003777)1.87316610
100Bone marrow hypocellularity (HP:0005528)1.87053419
101Absent/shortened dynein arms (HP:0200106)1.86773077
102Dynein arm defect of respiratory motile cilia (HP:0012255)1.86773077
103Biliary tract neoplasm (HP:0100574)1.86238915
104Absent thumb (HP:0009777)1.86016254
105Megaloblastic anemia (HP:0001889)1.85910967
106Neoplasm of striated muscle (HP:0009728)1.85874736
107Tracheoesophageal fistula (HP:0002575)1.85647087
108Progressive muscle weakness (HP:0003323)1.85332995
109Aplasia involving forearm bones (HP:0009822)1.84930482
110Absent forearm bone (HP:0003953)1.84930482
111Deep philtrum (HP:0002002)1.84839679
112Abnormality of the labia minora (HP:0012880)1.84754054
113Abnormality of oral frenula (HP:0000190)1.83777078
114Aplasia/Hypoplasia of the sacrum (HP:0008517)1.83167388
115Abnormality of the renal collecting system (HP:0004742)1.82298431
116Amaurosis fugax (HP:0100576)1.82206766
117Ovarian neoplasm (HP:0100615)1.82175593
118Abnormal umbilical cord blood vessels (HP:0011403)1.81726539
119Single umbilical artery (HP:0001195)1.81726539
120Abnormality of the fetal cardiovascular system (HP:0010948)1.81726539
121Trismus (HP:0000211)1.80171655
122Broad distal phalanx of finger (HP:0009836)1.79621459
123Abnormality of the pancreatic islet cells (HP:0006476)1.79529888
124Abnormality of endocrine pancreas physiology (HP:0012093)1.79529888
125Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.78493356
126Absent epiphyses (HP:0010577)1.78493356
127Abnormality of the labia majora (HP:0012881)1.77870883
128Pancreatic islet-cell hyperplasia (HP:0004510)1.77579680
129Horseshoe kidney (HP:0000085)1.76957451
130Progressive external ophthalmoplegia (HP:0000590)1.75284103
131Shawl scrotum (HP:0000049)1.75249062
132Homocystinuria (HP:0002156)1.74099527
133Abnormality of homocysteine metabolism (HP:0010919)1.74099527
134Insomnia (HP:0100785)1.73871029
135Sparse lateral eyebrow (HP:0005338)1.73601230
136Freckling (HP:0001480)1.73098919
137Back pain (HP:0003418)1.72991127
138Abnormality of the salivary glands (HP:0010286)1.72540822
139Arnold-Chiari malformation (HP:0002308)1.72066987
140Male infertility (HP:0003251)1.71250119
141Triphalangeal thumb (HP:0001199)1.71123270
142Cortical dysplasia (HP:0002539)1.70423159
143Abnormal biliary tract morphology (HP:0012440)1.70401796
144Aplasia/hypoplasia of the humerus (HP:0006507)1.70245733
145Short thumb (HP:0009778)1.70200557
146Abnormal glycosylation (HP:0012345)1.70166086
147Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.70166086
148Abnormal protein N-linked glycosylation (HP:0012347)1.70166086
149Abnormal protein glycosylation (HP:0012346)1.70166086
150Long palpebral fissure (HP:0000637)1.67352207
151Myelomeningocele (HP:0002475)1.65680513
152Partial duplication of thumb phalanx (HP:0009944)1.64171590
153Advanced eruption of teeth (HP:0006288)1.62664750
154Gout (HP:0001997)1.61651562
155Spinal cord compression (HP:0002176)1.61571764
156Bronchiectasis (HP:0002110)1.60389709
157Abnormalities of placenta or umbilical cord (HP:0001194)1.60002392
158Testicular atrophy (HP:0000029)1.59441506
159Glossoptosis (HP:0000162)1.59376652
160Uterine leiomyosarcoma (HP:0002891)1.58609291
161Leiomyosarcoma (HP:0100243)1.58609291
162Abnormality of the calcaneus (HP:0008364)1.58522781
163Choanal atresia (HP:0000453)1.58442094
164Progressive hearing impairment (HP:0001730)1.58243460
165Malignant gastrointestinal tract tumors (HP:0006749)1.58142630
166Gastrointestinal carcinoma (HP:0002672)1.58142630
167Pseudobulbar signs (HP:0002200)1.57585092
168Elfin facies (HP:0004428)1.57298994
169Bifid scrotum (HP:0000048)1.56604761
170Abnormality of the phalanges of the hallux (HP:0010057)1.56044028
171Natal tooth (HP:0000695)1.54311226
172Abnormality of nail color (HP:0100643)1.51844261
173Patellar dislocation (HP:0002999)1.51650162
174Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.51532894
175Vertebral hypoplasia (HP:0008417)1.51532894

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.20368481
2PASK3.47304525
3WEE13.41419538
4TRIB33.22450354
5BUB13.19824559
6SMG13.12549823
7TTK2.59547146
8EIF2AK32.48386743
9SRPK12.46914175
10NEK22.45393589
11BRSK22.31653994
12ACVR1B2.24987765
13CDK122.22978652
14EIF2AK12.18009167
15NEK12.16348872
16PLK42.01258331
17MKNK12.00389001
18ATR1.93774764
19CDK71.91624853
20MST1R1.86475863
21PLK11.86329679
22VRK21.80147496
23EPHA21.74063110
24ICK1.72661141
25RPS6KA41.69202349
26AURKB1.68278634
27VRK11.68108991
28ZAK1.65975491
29RPS6KB21.64506767
30FLT31.62252667
31TLK11.60688674
32TESK21.59058676
33TSSK61.58919223
34CHEK21.57149707
35DYRK31.51711460
36PLK31.48827896
37TGFBR11.47321470
38PNCK1.46546535
39SCYL21.44290954
40LATS11.43971542
41MST41.42300044
42TAF11.41026154
43MAP3K81.36991987
44SIK11.29622347
45BRSK11.26168883
46PAK41.25913173
47MKNK21.24471637
48CHEK11.20597486
49AURKA1.16282758
50CDK41.12647463
51BRD41.11463642
52MAP3K91.09786243
53PTK21.07240734
54STK101.05355616
55ATM1.04022782
56PDGFRA1.02505540
57STK161.01607042
58STK38L1.01505147
59STK40.94825469
60FGFR40.94178346
61NME20.94099576
62MAP3K100.93560875
63TESK10.90601616
64CAMK1G0.90258492
65EEF2K0.88731433
66* CDK20.88271264
67CDK80.85896139
68NME10.83039097
69DMPK0.82913255
70STK240.80600414
71CDK60.79460903
72STK30.78814472
73ERBB40.78227063
74ALK0.77092358
75PRKCI0.76916215
76CAMK1D0.76565798
77ILK0.76275352
78EIF2AK20.69267962
79MAPK150.69084264
80PRKD30.68639201
81BRAF0.67626642
82CDK10.67373115
83PKN20.66534809
84PBK0.62732379
85CCNB10.61694039
86PIM10.61367775
87MELK0.60540842
88AKT20.60351029
89YES10.59363257
90WNK30.58490204
91MTOR0.58286264
92CSNK2A20.58111773
93NTRK10.57682621
94RIPK10.56826013
95CSNK2A10.56802931
96MAP2K30.52539996
97TTN0.50438709
98RPS6KA50.49720964
99BCR0.49231751
100BMX0.49211824
101PAK20.49029711
102INSRR0.48684163
103MAP3K60.48508066
104KDR0.46951673
105TRIM280.46379588
106LMTK20.45891437
107MAPKAPK30.45411442
108PAK10.45009416
109EPHB20.42721881
110MAP2K20.41977247
111MET0.41864855
112ARAF0.41695490
113FGFR10.41594496
114PRKDC0.41437409
115NEK90.40644928
116CDK90.40211462
117KSR20.39706291
118NEK60.39394399
119BTK0.39344538
120ERBB30.39323939
121IRAK30.38867438
122HIPK20.37269081
123IRAK40.36180056
124AKT10.35354881
125DYRK20.34781294
126MAPK140.33650660
127TEC0.33171304
128LATS20.31612161
129CLK10.31374914
130RPS6KB10.31313589
131DYRK1B0.31306859
132CHUK0.31255597
133LRRK20.30415238
134ERN10.29385602
135CSNK1E0.29367702
136BCKDK0.29212878
137MAP3K110.27514278
138PTK60.27454039
139LIMK10.27319466

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.05019208
2Mismatch repair_Homo sapiens_hsa034304.56444214
3One carbon pool by folate_Homo sapiens_hsa006703.15353812
4Base excision repair_Homo sapiens_hsa034103.09764878
5Spliceosome_Homo sapiens_hsa030403.05313633
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.03531814
7Homologous recombination_Homo sapiens_hsa034403.02381334
8Cell cycle_Homo sapiens_hsa041102.93765834
9RNA transport_Homo sapiens_hsa030132.90893746
10Nucleotide excision repair_Homo sapiens_hsa034202.86144560
11Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.48720214
12RNA polymerase_Homo sapiens_hsa030202.33971187
13Protein export_Homo sapiens_hsa030602.28882772
14Fanconi anemia pathway_Homo sapiens_hsa034602.25309858
15Non-homologous end-joining_Homo sapiens_hsa034502.20146870
16Pyrimidine metabolism_Homo sapiens_hsa002402.18673872
17Proteasome_Homo sapiens_hsa030502.17715049
18Ribosome_Homo sapiens_hsa030102.05005487
19Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.95465284
20RNA degradation_Homo sapiens_hsa030181.89100026
21Maturity onset diabetes of the young_Homo sapiens_hsa049501.87116790
22Basal transcription factors_Homo sapiens_hsa030221.78827440
23mRNA surveillance pathway_Homo sapiens_hsa030151.72726907
24p53 signaling pathway_Homo sapiens_hsa041151.67781502
25Vitamin B6 metabolism_Homo sapiens_hsa007501.58834462
262-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.50735645
27Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.43855301
28Selenocompound metabolism_Homo sapiens_hsa004501.38102467
29Systemic lupus erythematosus_Homo sapiens_hsa053221.35765291
30Pyruvate metabolism_Homo sapiens_hsa006201.27305265
31Folate biosynthesis_Homo sapiens_hsa007901.19700741
32N-Glycan biosynthesis_Homo sapiens_hsa005101.17837358
33Phenylalanine metabolism_Homo sapiens_hsa003601.17131776
34Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.10412191
35Purine metabolism_Homo sapiens_hsa002301.08125108
36Viral carcinogenesis_Homo sapiens_hsa052031.05578831
37Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.01471624
38Endometrial cancer_Homo sapiens_hsa052130.95513399
39Herpes simplex infection_Homo sapiens_hsa051680.95352149
40Epstein-Barr virus infection_Homo sapiens_hsa051690.94173799
41Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.93189924
42Antigen processing and presentation_Homo sapiens_hsa046120.90223913
43Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.87269561
44Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.85483425
45Thyroid cancer_Homo sapiens_hsa052160.83892898
46Basal cell carcinoma_Homo sapiens_hsa052170.83181542
47Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.82823627
48Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.81269802
49MicroRNAs in cancer_Homo sapiens_hsa052060.80473263
50HTLV-I infection_Homo sapiens_hsa051660.75937172
51Tyrosine metabolism_Homo sapiens_hsa003500.73468855
52Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.73083842
53Drug metabolism - other enzymes_Homo sapiens_hsa009830.72694425
54Arginine and proline metabolism_Homo sapiens_hsa003300.72100289
55Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.67367476
56Legionellosis_Homo sapiens_hsa051340.66485028
57Adherens junction_Homo sapiens_hsa045200.66420799
58Oocyte meiosis_Homo sapiens_hsa041140.65980727
59Hippo signaling pathway_Homo sapiens_hsa043900.65979482
60Non-small cell lung cancer_Homo sapiens_hsa052230.64376717
61Transcriptional misregulation in cancer_Homo sapiens_hsa052020.64044808
62Arginine biosynthesis_Homo sapiens_hsa002200.63077773
63Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.62156563
64Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.61694038
65TGF-beta signaling pathway_Homo sapiens_hsa043500.60525635
66Cysteine and methionine metabolism_Homo sapiens_hsa002700.59921332
67Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.58530127
68Small cell lung cancer_Homo sapiens_hsa052220.58331128
69Biosynthesis of amino acids_Homo sapiens_hsa012300.58104185
70Thyroid hormone signaling pathway_Homo sapiens_hsa049190.58054976
71Fatty acid elongation_Homo sapiens_hsa000620.57385724
72Alcoholism_Homo sapiens_hsa050340.56369708
73Renal cell carcinoma_Homo sapiens_hsa052110.55461121
74Lysine degradation_Homo sapiens_hsa003100.54742577
75Hedgehog signaling pathway_Homo sapiens_hsa043400.52256740
76Notch signaling pathway_Homo sapiens_hsa043300.52041074
77Insulin signaling pathway_Homo sapiens_hsa049100.50282204
78Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.49893697
79Fatty acid metabolism_Homo sapiens_hsa012120.48965783
80Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.48772271
81Bladder cancer_Homo sapiens_hsa052190.48593931
82Huntingtons disease_Homo sapiens_hsa050160.47007999
83Colorectal cancer_Homo sapiens_hsa052100.44944601
84ECM-receptor interaction_Homo sapiens_hsa045120.44130239
85Other glycan degradation_Homo sapiens_hsa005110.43819309
86AMPK signaling pathway_Homo sapiens_hsa041520.43781628
87Pentose and glucuronate interconversions_Homo sapiens_hsa000400.43439851
88ErbB signaling pathway_Homo sapiens_hsa040120.43009471
89Glutathione metabolism_Homo sapiens_hsa004800.42789893
90Pentose phosphate pathway_Homo sapiens_hsa000300.42753271
91beta-Alanine metabolism_Homo sapiens_hsa004100.40753172
92Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.40354049
93Renin-angiotensin system_Homo sapiens_hsa046140.40137356
94Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.39940074
95Galactose metabolism_Homo sapiens_hsa000520.38853667
96Glioma_Homo sapiens_hsa052140.37771051
97Cyanoamino acid metabolism_Homo sapiens_hsa004600.37582175
98Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.37478262
99Prostate cancer_Homo sapiens_hsa052150.36975609
100Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.36087813
101Apoptosis_Homo sapiens_hsa042100.34550919
102Shigellosis_Homo sapiens_hsa051310.32940969
103Chronic myeloid leukemia_Homo sapiens_hsa052200.31774403
104Hepatitis B_Homo sapiens_hsa051610.30836098
105Pathways in cancer_Homo sapiens_hsa052000.29355305
106Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.27946205
107Glycosaminoglycan degradation_Homo sapiens_hsa005310.26882400
108Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.25955141
109Wnt signaling pathway_Homo sapiens_hsa043100.25318210
110Sulfur relay system_Homo sapiens_hsa041220.23421735
111Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.23218622
112NF-kappa B signaling pathway_Homo sapiens_hsa040640.23014256
113Fructose and mannose metabolism_Homo sapiens_hsa000510.22860589
114Measles_Homo sapiens_hsa051620.22549350
115Central carbon metabolism in cancer_Homo sapiens_hsa052300.19658332
116Influenza A_Homo sapiens_hsa051640.19240050
117PI3K-Akt signaling pathway_Homo sapiens_hsa041510.17819468
118Pancreatic cancer_Homo sapiens_hsa052120.16871127
119Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.16808113
120Melanoma_Homo sapiens_hsa052180.16522348
121Arachidonic acid metabolism_Homo sapiens_hsa005900.15531676
122Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.15419918
123Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.14866826
124Tight junction_Homo sapiens_hsa045300.14505316
125Linoleic acid metabolism_Homo sapiens_hsa005910.14334630
126Steroid biosynthesis_Homo sapiens_hsa001000.13906332
127Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.13639421
128Metabolic pathways_Homo sapiens_hsa011000.13000145
129Proteoglycans in cancer_Homo sapiens_hsa052050.12709434
130Viral myocarditis_Homo sapiens_hsa054160.12571717
131Carbon metabolism_Homo sapiens_hsa012000.12126764

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