HNRNPA0

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind RNAs, followed by a glycine-rich C-terminus. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of mRNA splicing, via spliceosome (GO:0048025)4.42811329
2negative regulation of RNA splicing (GO:0033119)4.19705231
3DNA unwinding involved in DNA replication (GO:0006268)4.15910909
4negative regulation of mRNA processing (GO:0050686)3.91503135
5pre-miRNA processing (GO:0031054)3.76612672
6protein localization to kinetochore (GO:0034501)3.67271817
7heterochromatin organization (GO:0070828)3.65058772
8convergent extension (GO:0060026)3.62300957
9regulation of NFAT protein import into nucleus (GO:0051532)3.49324987
10establishment of integrated proviral latency (GO:0075713)3.46107562
11regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.42352310
12sister chromatid segregation (GO:0000819)3.39903700
13negative regulation of mRNA metabolic process (GO:1903312)3.38530698
14alternative mRNA splicing, via spliceosome (GO:0000380)3.35747022
15protein-DNA complex disassembly (GO:0032986)3.33975781
16nucleosome disassembly (GO:0006337)3.33975781
17viral transcription (GO:0019083)3.31428631
18mitotic sister chromatid cohesion (GO:0007064)3.25603831
19* RNA stabilization (GO:0043489)3.22705055
20* mRNA stabilization (GO:0048255)3.22705055
21planar cell polarity pathway involved in neural tube closure (GO:0090179)3.16595839
22translational termination (GO:0006415)3.16346326
23nuclear pore complex assembly (GO:0051292)3.15224846
24protein complex localization (GO:0031503)3.15092360
25paraxial mesoderm development (GO:0048339)3.14203415
26peptidyl-arginine omega-N-methylation (GO:0035247)3.13583852
27dosage compensation (GO:0007549)3.12069270
28mitotic metaphase plate congression (GO:0007080)3.11566470
29V(D)J recombination (GO:0033151)3.08740288
30DNA topological change (GO:0006265)3.07197916
31nuclear pore organization (GO:0006999)3.06920360
32regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.06684137
33mitotic sister chromatid segregation (GO:0000070)3.06225463
34regulation of sister chromatid cohesion (GO:0007063)3.06095133
35negative regulation of histone methylation (GO:0031061)3.06000272
36peptidyl-arginine N-methylation (GO:0035246)3.04558365
37peptidyl-arginine methylation (GO:0018216)3.04558365
38regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.02358177
39nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.01783325
40protein localization to chromosome, centromeric region (GO:0071459)2.99553614
41glucocorticoid receptor signaling pathway (GO:0042921)2.94744779
42chromatin assembly (GO:0031497)2.90482622
43DNA strand elongation involved in DNA replication (GO:0006271)2.88274721
44chromosome condensation (GO:0030261)2.85906850
45regulation of RNA export from nucleus (GO:0046831)2.84809510
46negative regulation of DNA repair (GO:0045738)2.84426088
47DNA strand elongation (GO:0022616)2.79911901
48hippo signaling (GO:0035329)2.79494667
49regulation of telomere maintenance via telomerase (GO:0032210)2.78961824
50G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.78448107
51ribosomal small subunit assembly (GO:0000028)2.77746190
52Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.76865905
53* regulation of mRNA stability (GO:0043488)2.76320946
54mRNA splice site selection (GO:0006376)2.75027935
55regulation of stem cell maintenance (GO:2000036)2.74602745
56regulation of histone H3-K9 methylation (GO:0051570)2.74601595
57cellular protein complex localization (GO:0034629)2.74022639
58polarized epithelial cell differentiation (GO:0030859)2.73774674
59translational elongation (GO:0006414)2.73770210
60DNA ligation (GO:0006266)2.73599005
61spliceosomal tri-snRNP complex assembly (GO:0000244)2.72563208
62regulation of chromatin binding (GO:0035561)2.72123044
63positive regulation of RNA splicing (GO:0033120)2.71950769
64proximal/distal pattern formation (GO:0009954)2.71356195
65DNA duplex unwinding (GO:0032508)2.69398518
66translational initiation (GO:0006413)2.69125562
67regulation of establishment of planar polarity (GO:0090175)2.67940103
68cell migration in hindbrain (GO:0021535)2.67677679
69* RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.67593558
70* mRNA splicing, via spliceosome (GO:0000398)2.67593558
71DNA geometric change (GO:0032392)2.65720558
72* RNA splicing, via transesterification reactions (GO:0000375)2.65328205
73establishment of apical/basal cell polarity (GO:0035089)2.64077909
74protein complex disassembly (GO:0043241)2.63724019
75notochord development (GO:0030903)2.62780307
76termination of RNA polymerase II transcription (GO:0006369)2.62055117
77mitotic nuclear envelope disassembly (GO:0007077)2.61085293
78regulation of translational fidelity (GO:0006450)2.60559897
79intracellular estrogen receptor signaling pathway (GO:0030520)2.59496499
80regulation of hippo signaling (GO:0035330)2.59459753
81metaphase plate congression (GO:0051310)2.59348569
82DNA replication initiation (GO:0006270)2.58478364
83* regulation of RNA stability (GO:0043487)2.57856992
84peptidyl-lysine dimethylation (GO:0018027)2.57646154
85regulation of mammary gland epithelial cell proliferation (GO:0033599)2.56535936
86regulation of gene silencing by RNA (GO:0060966)2.55664736
87regulation of posttranscriptional gene silencing (GO:0060147)2.55664736
88regulation of gene silencing by miRNA (GO:0060964)2.55664736
89L-serine metabolic process (GO:0006563)2.55588281
90protein localization to chromosome (GO:0034502)2.54451690
91somatic stem cell division (GO:0048103)2.53470929
92positive regulation of cell cycle checkpoint (GO:1901978)2.52170142
93glial cell proliferation (GO:0014009)2.51514767
94viral life cycle (GO:0019058)2.51100243
95cellular protein complex disassembly (GO:0043624)2.50826871
96mitotic chromosome condensation (GO:0007076)2.50816229
97chromatin assembly or disassembly (GO:0006333)2.50274505
98positive regulation of chromosome segregation (GO:0051984)2.50000017
99gastrulation with mouth forming second (GO:0001702)2.49642978
100histone arginine methylation (GO:0034969)2.48343675
101establishment of monopolar cell polarity (GO:0061162)2.47706340
102establishment or maintenance of monopolar cell polarity (GO:0061339)2.47706340
103DNA conformation change (GO:0071103)2.47667546
104membrane disassembly (GO:0030397)2.46694419
105nuclear envelope disassembly (GO:0051081)2.46694419
106positive regulation of gene expression, epigenetic (GO:0045815)2.46411124
107mRNA transport (GO:0051028)2.46147524
108maturation of SSU-rRNA (GO:0030490)2.45895040
109DNA replication-dependent nucleosome assembly (GO:0006335)2.45557018
110DNA replication-dependent nucleosome organization (GO:0034723)2.45557018
111ribosomal small subunit biogenesis (GO:0042274)2.45002035
112positive regulation of transcription regulatory region DNA binding (GO:2000679)2.43647590
113kinetochore organization (GO:0051383)2.41338671
114positive regulation of cell cycle G2/M phase transition (GO:1902751)2.40831951
115positive regulation of G2/M transition of mitotic cell cycle (GO:0010971)2.40831951
116lateral sprouting from an epithelium (GO:0060601)2.40523690
117ATP-dependent chromatin remodeling (GO:0043044)2.40472205
118head development (GO:0060322)2.40455017
119regulation of protein heterodimerization activity (GO:0043497)2.40290020
120macromolecular complex disassembly (GO:0032984)2.39149003
121outer ear morphogenesis (GO:0042473)2.39123818
122ectodermal placode formation (GO:0060788)2.38977571
123negative regulation of gene expression, epigenetic (GO:0045814)2.38624167
124chromatin remodeling (GO:0006338)2.38469741
125generation of neurons (GO:0048699)2.38299645
126establishment of viral latency (GO:0019043)2.38046164
127negative regulation of histone modification (GO:0031057)2.37918671
128regulation of nucleobase-containing compound transport (GO:0032239)2.37517966
129corticosteroid receptor signaling pathway (GO:0031958)2.37346165
130lung-associated mesenchyme development (GO:0060484)2.37055694
131presynaptic membrane assembly (GO:0097105)2.36451426
132positive regulation of SMAD protein import into nucleus (GO:0060391)2.36202415
133negative regulation of histone acetylation (GO:0035067)2.35825012
134establishment of chromosome localization (GO:0051303)2.35409700
135regulation of transcription from RNA polymerase II promoter involved in heart development (GO:1901212.35043028
136formation of translation preinitiation complex (GO:0001731)2.34782745
137nuclear-transcribed mRNA catabolic process (GO:0000956)2.33365969
138histone H3-K9 demethylation (GO:0033169)2.32181361

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.93657213
2FOXM1_23109430_ChIP-Seq_U2OS_Human5.61752913
3MYC_22102868_ChIP-Seq_BL_Human3.62775833
4EGR1_19374776_ChIP-ChIP_THP-1_Human3.55299737
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.43827964
6TP63_19390658_ChIP-ChIP_HaCaT_Human3.09133161
7* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.93113273
8MYC_18555785_ChIP-Seq_MESCs_Mouse2.92916128
9NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.60185836
10ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.57446791
11MYC_19079543_ChIP-ChIP_MESCs_Mouse2.54150086
12STAT6_21828071_ChIP-Seq_BEAS2B_Human2.43978060
13EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.38589044
14RBPJ_22232070_ChIP-Seq_NCS_Mouse2.16563616
15VDR_21846776_ChIP-Seq_THP-1_Human2.11374990
16KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.05354088
17ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.04645447
18ZFP281_18757296_ChIP-ChIP_E14_Mouse2.03134604
19* ZFP281_27345836_Chip-Seq_ESCs_Mouse2.00948310
20* TCF7_22412390_ChIP-Seq_EML_Mouse1.93370132
21KDM2B_26808549_Chip-Seq_DND41_Human1.90004310
22EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.83463176
23SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.80890058
24E2F1_21310950_ChIP-Seq_MCF-7_Human1.79699648
25SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.78695973
26XRN2_22483619_ChIP-Seq_HELA_Human1.76990691
27KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.76115766
28MYC_19030024_ChIP-ChIP_MESCs_Mouse1.75902151
29KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.75323598
30TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.73475739
31WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.68954583
32KDM2B_26808549_Chip-Seq_SUP-B15_Human1.68839794
33CIITA_25753668_ChIP-Seq_RAJI_Human1.67952285
34SOX2_18555785_ChIP-Seq_MESCs_Mouse1.65602238
35SALL1_21062744_ChIP-ChIP_HESCs_Human1.63669628
36KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.61711323
37KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.58148075
38KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.58148075
39KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.58148075
40HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.56472784
41KDM2B_26808549_Chip-Seq_JURKAT_Human1.56394473
42ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.53137825
43ELK3_25401928_ChIP-Seq_HUVEC_Human1.52067276
44CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.50670091
45NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.46878653
46TTF2_22483619_ChIP-Seq_HELA_Human1.45298608
47NANOG_21062744_ChIP-ChIP_HESCs_Human1.43579004
48DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.42522810
49AR_21909140_ChIP-Seq_LNCAP_Human1.41907355
50* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.41397564
51PKCTHETA_26484144_Chip-Seq_BREAST_Human1.39638090
52MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.39547855
53NANOG_18555785_ChIP-Seq_MESCs_Mouse1.35938876
54HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.35656869
55TP63_17297297_ChIP-ChIP_HaCaT_Human1.35517748
56ESR1_15608294_ChIP-ChIP_MCF-7_Human1.34400367
57CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.34276257
58SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.33871976
59NELFA_20434984_ChIP-Seq_ESCs_Mouse1.32255210
60RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.32038549
61* FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.31589159
62EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.30484504
63CLOCK_20551151_ChIP-Seq_293T_Human1.29796325
64THAP11_20581084_ChIP-Seq_MESCs_Mouse1.29625413
65TCF3_18692474_ChIP-Seq_MEFs_Mouse1.28271942
66POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.27161386
67* UTX_26944678_Chip-Seq_JUKART_Human1.26781365
68TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.26387313
69DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.25797911
70HIF1A_21447827_ChIP-Seq_MCF-7_Human1.25476543
71ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.24816424
72* CHD1_26751641_Chip-Seq_LNCaP_Human1.24245499
73TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.23699925
74P300_27058665_Chip-Seq_ZR-75-30cells_Human1.23393491
75MYCN_18555785_ChIP-Seq_MESCs_Mouse1.23307491
76MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.23190472
77NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.19575893
78ERG_21242973_ChIP-ChIP_JURKAT_Human1.18924924
79SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.16644285
80KDM2B_26808549_Chip-Seq_K562_Human1.16347413
81ZNF263_19887448_ChIP-Seq_K562_Human1.16185634
82CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.15442875
83SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.15432872
84KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.13939017
85MYC_18358816_ChIP-ChIP_MESCs_Mouse1.13152508
86GATA1_26923725_Chip-Seq_HPCs_Mouse1.12648797
87SOX2_16153702_ChIP-ChIP_HESCs_Human1.10828640
88MAF_26560356_Chip-Seq_TH1_Human1.10624120
89KDM5A_27292631_Chip-Seq_BREAST_Human1.10232999
90ZFX_18555785_ChIP-Seq_MESCs_Mouse1.09973850
91CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.09226986
92WT1_19549856_ChIP-ChIP_CCG9911_Human1.09124804
93POU5F1_16153702_ChIP-ChIP_HESCs_Human1.08594151
94KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.06931616
95NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.06150677
96PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.06098793
97NCOR1_26117541_ChIP-Seq_K562_Human1.05419769
98DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.04833568
99* RING1B_27294783_Chip-Seq_NPCs_Mouse1.04282774
100POU5F1_16518401_ChIP-PET_MESCs_Mouse1.04000921
101NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.03933480
102KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.03831509
103KLF4_18555785_ChIP-Seq_MESCs_Mouse1.03206080
104ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.02243816
105TCF3_18692474_ChIP-Seq_MESCs_Mouse1.01240198
106POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.00803434
107RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.00122042
108NANOG_16153702_ChIP-ChIP_HESCs_Human0.99713405
109YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.99453589
110HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.99253081
111ISL1_27105846_Chip-Seq_CPCs_Mouse0.98454499
112OCT4_18692474_ChIP-Seq_MEFs_Mouse0.97599451
113PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.97505944
114* OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.97500721
115* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.95493195
116* TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.95449941
117TP53_20018659_ChIP-ChIP_R1E_Mouse0.94791981
118CREB1_26743006_Chip-Seq_LNCaP_Human0.94642727
119VDR_24763502_ChIP-Seq_THP-1_Human0.93260360
120UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.92270635
121POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.92076822

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000566_synostosis3.10340530
2MP0000537_abnormal_urethra_morphology2.81025545
3MP0010030_abnormal_orbit_morphology2.78144850
4MP0009053_abnormal_anal_canal2.48517778
5MP0003705_abnormal_hypodermis_morpholog2.47074227
6MP0003123_paternal_imprinting2.35882476
7MP0005076_abnormal_cell_differentiation2.31095613
8MP0003111_abnormal_nucleus_morphology2.25323435
9MP0010352_gastrointestinal_tract_polyps2.20415641
10MP0003121_genomic_imprinting2.08648983
11MP0003122_maternal_imprinting2.04720622
12MP0004957_abnormal_blastocyst_morpholog2.02476514
13MP0003385_abnormal_body_wall2.01175039
14MP0010094_abnormal_chromosome_stability2.00186441
15MP0008057_abnormal_DNA_replication1.99473679
16MP0003077_abnormal_cell_cycle1.98746961
17MP0001346_abnormal_lacrimal_gland1.92552785
18MP0003119_abnormal_digestive_system1.87953665
19MP0004197_abnormal_fetal_growth/weight/1.79642502
20MP0009278_abnormal_bone_marrow1.78840611
21MP0002084_abnormal_developmental_patter1.72874173
22MP0003693_abnormal_embryo_hatching1.69040093
23MP0000049_abnormal_middle_ear1.68988554
24MP0001730_embryonic_growth_arrest1.68634096
25MP0002085_abnormal_embryonic_tissue1.68564696
26MP0003567_abnormal_fetal_cardiomyocyte1.65317681
27MP0000350_abnormal_cell_proliferation1.65232769
28MP0003942_abnormal_urinary_system1.58443267
29MP0008789_abnormal_olfactory_epithelium1.58250993
30MP0003935_abnormal_craniofacial_develop1.53459973
31MP0000428_abnormal_craniofacial_morphol1.53328116
32MP0005380_embryogenesis_phenotype1.52377466
33MP0001672_abnormal_embryogenesis/_devel1.52377466
34MP0000733_abnormal_muscle_development1.51613967
35MP0005623_abnormal_meninges_morphology1.50737800
36MP0002282_abnormal_trachea_morphology1.50656966
37MP0004808_abnormal_hematopoietic_stem1.48839828
38MP0003115_abnormal_respiratory_system1.48709579
39MP0009250_abnormal_appendicular_skeleto1.48408436
40MP0008007_abnormal_cellular_replicative1.48396352
41MP0003937_abnormal_limbs/digits/tail_de1.48016021
42MP0001697_abnormal_embryo_size1.47839575
43MP0003890_abnormal_embryonic-extraembry1.46637146
44MP0001293_anophthalmia1.46211813
45MP0002086_abnormal_extraembryonic_tissu1.45536411
46MP0003755_abnormal_palate_morphology1.44359439
47MP0002932_abnormal_joint_morphology1.44032315
48MP0002249_abnormal_larynx_morphology1.40029984
49MP0002088_abnormal_embryonic_growth/wei1.39983932
50MP0003984_embryonic_growth_retardation1.39576627
51MP0002396_abnormal_hematopoietic_system1.37773051
52MP0005248_abnormal_Harderian_gland1.34463163
53MP0005367_renal/urinary_system_phenotyp1.32907469
54MP0000516_abnormal_urinary_system1.32907469
55MP0003303_peritoneal_inflammation1.32271126
56MP0008932_abnormal_embryonic_tissue1.31662769
57MP0001849_ear_inflammation1.31371798
58MP0003861_abnormal_nervous_system1.30613394
59MP0002653_abnormal_ependyma_morphology1.29920936
60MP0005499_abnormal_olfactory_system1.28011767
61MP0005394_taste/olfaction_phenotype1.28011767
62MP0002116_abnormal_craniofacial_bone1.27092582
63MP0000534_abnormal_ureter_morphology1.26929487
64MP0002697_abnormal_eye_size1.24704039
65MP0001188_hyperpigmentation1.24300519
66MP0003283_abnormal_digestive_organ1.23530923
67MP0002938_white_spotting1.22588765
68MP0002092_abnormal_eye_morphology1.21480970
69MP0003787_abnormal_imprinting1.21366556
70MP0004185_abnormal_adipocyte_glucose1.20479817
71MP0001286_abnormal_eye_development1.20248710
72MP0000432_abnormal_head_morphology1.19431094
73MP0000579_abnormal_nail_morphology1.19331256
74MP0003938_abnormal_ear_development1.17410598
75MP0002080_prenatal_lethality1.17145084
76MP0002925_abnormal_cardiovascular_devel1.16805078
77MP0003315_abnormal_perineum_morphology1.16790461
78MP0002233_abnormal_nose_morphology1.15920262
79MP0006054_spinal_hemorrhage1.15900890
80MP0002111_abnormal_tail_morphology1.11124841
81MP0002089_abnormal_postnatal_growth/wei1.11043734
82MP0005257_abnormal_intraocular_pressure1.08175507
83MP0001299_abnormal_eye_distance/1.07228493
84MP0005187_abnormal_penis_morphology1.05667707
85MP0002822_catalepsy1.04866323
86MP0006292_abnormal_olfactory_placode1.04823086
87MP0002114_abnormal_axial_skeleton1.04341190
88MP0002081_perinatal_lethality1.04042001
89MP0001915_intracranial_hemorrhage1.03700740
90MP0005409_darkened_coat_color1.03186567
91MP0009703_decreased_birth_body1.02495208
92MP0004272_abnormal_basement_membrane1.01722182
93MP0010234_abnormal_vibrissa_follicle1.01579837
94MP0002152_abnormal_brain_morphology1.00364952
95MP0009672_abnormal_birth_weight0.99192307
96MP0002009_preneoplasia0.98959183
97MP0003941_abnormal_skin_development0.98627426
98MP0000490_abnormal_crypts_of0.97398955
99MP0004133_heterotaxia0.96578885
100MP0002751_abnormal_autonomic_nervous0.96535963
101MP0000631_abnormal_neuroendocrine_gland0.96246059
102MP0009379_abnormal_foot_pigmentation0.96017274
103MP0000762_abnormal_tongue_morphology0.92604264
104MP0010307_abnormal_tumor_latency0.91336207
105MP0000703_abnormal_thymus_morphology0.90724609
106MP0001340_abnormal_eyelid_morphology0.90093767
107MP0002796_impaired_skin_barrier0.87663699
108MP0000955_abnormal_spinal_cord0.86912779
109MP0001879_abnormal_lymphatic_vessel0.86413345
110MP0008058_abnormal_DNA_repair0.85230175
111MP0004859_abnormal_synaptic_plasticity0.84010110
112MP0002109_abnormal_limb_morphology0.83625086
113MP0004858_abnormal_nervous_system0.82756960
114MP0010368_abnormal_lymphatic_system0.82186342
115MP0005508_abnormal_skeleton_morphology0.80732668
116MP0000778_abnormal_nervous_system0.80334631
117MP0001545_abnormal_hematopoietic_system0.79476098
118MP0005397_hematopoietic_system_phenotyp0.79476098
119MP0001784_abnormal_fluid_regulation0.78370173
120MP0001177_atelectasis0.78340150

Predicted human phenotypes

RankGene SetZ-score
1Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)4.05426231
2Short 4th metacarpal (HP:0010044)4.05426231
3Renal duplication (HP:0000075)3.27345898
4Abnormality of the 4th metacarpal (HP:0010012)3.09544446
5Shallow orbits (HP:0000586)2.93566966
6Asymmetry of the thorax (HP:0001555)2.87032094
7Hyperacusis (HP:0010780)2.83607932
8Cortical dysplasia (HP:0002539)2.69424900
9Colon cancer (HP:0003003)2.60730671
10Turricephaly (HP:0000262)2.54564199
11Increased nuchal translucency (HP:0010880)2.53623211
12Medulloblastoma (HP:0002885)2.49746295
13Partial duplication of thumb phalanx (HP:0009944)2.28121304
14Arnold-Chiari malformation (HP:0002308)2.27521722
15Abnormal number of incisors (HP:0011064)2.27059130
16Supernumerary ribs (HP:0005815)2.23927931
17Increased density of long bones (HP:0006392)2.23098271
18Atresia of the external auditory canal (HP:0000413)2.22989371
19Subacute progressive viral hepatitis (HP:0006572)2.22484396
20Vitreoretinal degeneration (HP:0000655)2.21705793
21Partial duplication of the phalanx of hand (HP:0009999)2.20762486
22Astrocytoma (HP:0009592)2.17004257
23Abnormality of the astrocytes (HP:0100707)2.17004257
24Rectal prolapse (HP:0002035)2.16484020
25Abnormal lung lobation (HP:0002101)2.12824622
26Overlapping toe (HP:0001845)2.12057369
27Choanal stenosis (HP:0000452)2.09664595
28Renovascular hypertension (HP:0100817)2.08999818
29Hepatoblastoma (HP:0002884)2.08474497
30Spinal cord lesions (HP:0100561)2.07434733
31Syringomyelia (HP:0003396)2.07434733
32Volvulus (HP:0002580)2.07196373
33Selective tooth agenesis (HP:0001592)2.07110507
34Deviation of the hallux (HP:0010051)2.06723884
35Ependymoma (HP:0002888)2.05835012
36Hallux valgus (HP:0001822)2.05420105
37Overriding aorta (HP:0002623)2.04945339
38Deviation of the thumb (HP:0009603)2.04665222
39Abnormality of chromosome segregation (HP:0002916)2.03493053
40Protrusio acetabuli (HP:0003179)2.02397487
41Nephroblastoma (Wilms tumor) (HP:0002667)2.02248513
42Elfin facies (HP:0004428)2.02120756
43Proximal placement of thumb (HP:0009623)2.01825776
44Supernumerary bones of the axial skeleton (HP:0009144)2.00907260
45Broad thumb (HP:0011304)1.99263347
46Malignant gastrointestinal tract tumors (HP:0006749)1.97336329
47Gastrointestinal carcinoma (HP:0002672)1.97336329
48Broad palm (HP:0001169)1.97169347
49Thin ribs (HP:0000883)1.96356883
50Obsessive-compulsive behavior (HP:0000722)1.94614491
51Rib fusion (HP:0000902)1.94240247
52Abnormality of the aortic arch (HP:0012303)1.94120741
53Trigonocephaly (HP:0000243)1.93812566
54Patellar aplasia (HP:0006443)1.92269581
55Embryonal renal neoplasm (HP:0011794)1.92084623
56Abnormality of the calcaneus (HP:0008364)1.91579754
57Short phalanx of the thumb (HP:0009660)1.91338840
58Aplasia/Hypoplasia of the patella (HP:0006498)1.90887301
59Skin tags (HP:0010609)1.90496732
60Bowel diverticulosis (HP:0005222)1.90418481
61Germ cell neoplasia (HP:0100728)1.89388920
62Short 5th finger (HP:0009237)1.89003433
63Septo-optic dysplasia (HP:0100842)1.88426063
64Missing ribs (HP:0000921)1.87516136
65Abnormality of the diencephalon (HP:0010662)1.87490102
66Long palpebral fissure (HP:0000637)1.87374888
67Vertebral arch anomaly (HP:0008438)1.86992795
68Broad long bones (HP:0005622)1.86478045
69Facial hemangioma (HP:0000329)1.86248529
70Abnormality of the parietal bone (HP:0002696)1.86144250
71Duplication of thumb phalanx (HP:0009942)1.85476316
72Genu recurvatum (HP:0002816)1.84918866
73Pseudobulbar signs (HP:0002200)1.84857056
74Generalized hypotonia (HP:0001290)1.84464059
75Buphthalmos (HP:0000557)1.83549562
76Basal cell carcinoma (HP:0002671)1.83057942
77Coronal craniosynostosis (HP:0004440)1.82276682
78Bladder diverticulum (HP:0000015)1.81575005
79Broad phalanx (HP:0006009)1.81572721
80Spina bifida occulta (HP:0003298)1.81510123
81Broad distal phalanx of finger (HP:0009836)1.81200991
82Cutaneous syndactyly (HP:0012725)1.80787026
83Aplasia involving bones of the extremities (HP:0009825)1.80325498
84Aplasia involving bones of the upper limbs (HP:0009823)1.80325498
85Aplasia of the phalanges of the hand (HP:0009802)1.80325498
86Deep palmar crease (HP:0006191)1.79469821
87Disproportionate tall stature (HP:0001519)1.79379723
88Neoplasm of striated muscle (HP:0009728)1.79190968
89Cerebral aneurysm (HP:0004944)1.79124651
90Bronchomalacia (HP:0002780)1.78271773
91Spastic diplegia (HP:0001264)1.77838405
92Abnormality of the intervertebral disk (HP:0005108)1.77534128
93Abnormality of the fingertips (HP:0001211)1.77507736
94Long eyelashes (HP:0000527)1.77358031
95Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.77345583
96Short 1st metacarpal (HP:0010034)1.77345583
97Pointed chin (HP:0000307)1.77287276
98Abnormality of the distal phalanx of the thumb (HP:0009617)1.77070152
99Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.76802390
100Bilateral microphthalmos (HP:0007633)1.76734148
101Short middle phalanx of the 5th finger (HP:0004220)1.75708835
102High anterior hairline (HP:0009890)1.75312456
103Flat cornea (HP:0007720)1.75076122
104Abnormality of the phalanges of the hallux (HP:0010057)1.74488071
105Aplasia/Hypoplasia of the sternum (HP:0006714)1.73756333
106Leiomyosarcoma (HP:0100243)1.72786501
107Uterine leiomyosarcoma (HP:0002891)1.72786501
108Omphalocele (HP:0001539)1.72756962
109Ankyloglossia (HP:0010296)1.72350249
110Urethral obstruction (HP:0000796)1.72163486
111Preauricular skin tag (HP:0000384)1.71803668
112Chromosomal breakage induced by crosslinking agents (HP:0003221)1.71685040
113Lymphangioma (HP:0100764)1.71650335
114Midline defect of the nose (HP:0004122)1.70723763
115Transitional cell carcinoma of the bladder (HP:0006740)1.69137935
116Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.69018521
117Broad phalanges of the hand (HP:0009768)1.68648616
118Absent radius (HP:0003974)1.68585911
119Anal stenosis (HP:0002025)1.68514886
120Chin dimple (HP:0010751)1.68389085
121Reticulocytopenia (HP:0001896)1.68126818
122Sacral dimple (HP:0000960)1.67634881
123Patellar dislocation (HP:0002999)1.67446292
124Insomnia (HP:0100785)1.66490153
125Aqueductal stenosis (HP:0002410)1.65027531
126Ulnar bowing (HP:0003031)1.64921781
127Glioma (HP:0009733)1.64282667
128Megalocornea (HP:0000485)1.63904122
129Skull defect (HP:0001362)1.63818306
130Ectopic kidney (HP:0000086)1.63426157
131Radioulnar synostosis (HP:0002974)1.63420710
132Down-sloping shoulders (HP:0200021)1.63364582
133Intestinal polyp (HP:0005266)1.63188293
134Hemivertebrae (HP:0002937)1.62737481
135Neoplasm of the oral cavity (HP:0100649)1.62133120
136Cutis marmorata (HP:0000965)1.61955206
137Flared metaphyses (HP:0003015)1.61904060
138Chromsome breakage (HP:0040012)1.61379834
139Mitral valve prolapse (HP:0001634)1.61379602
140Broad finger (HP:0001500)1.60340024
141Acute lymphatic leukemia (HP:0006721)1.60330434
142Pelvic girdle muscle weakness (HP:0003749)1.60129332
143Fibrous tissue neoplasm (HP:0012316)1.58829592
144Bladder neoplasm (HP:0009725)1.58761350
145Bladder carcinoma (HP:0002862)1.58761350
146Myelomeningocele (HP:0002475)1.58738784
147Abnormality of the labia minora (HP:0012880)1.58668031
148Morphological abnormality of the middle ear (HP:0008609)1.58493226
149Short palpebral fissure (HP:0012745)1.57753074
150Rhabdomyosarcoma (HP:0002859)1.57694643
151Aplasia involving forearm bones (HP:0009822)1.57275577
152Absent forearm bone (HP:0003953)1.57275577

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K104.55317273
2EEF2K4.19172440
3SMG13.71636516
4CDK123.29987592
5PKN23.01667797
6TRIB32.91987531
7CDC72.81051202
8MKNK12.58180144
9MKNK22.35255365
10NEK22.21371904
11ICK2.13966944
12TAF12.09650841
13EPHB21.91909253
14ALK1.77247632
15RPS6KB21.75633826
16PRPF4B1.69901550
17PDGFRA1.63874290
18TGFBR11.62414241
19TYRO31.62127429
20VRK21.52309393
21CDK61.50881903
22SIK21.50222360
23SRPK11.48240259
24PTK61.47522497
25CDK41.44391507
26PASK1.41832601
27ERBB31.40956058
28RPS6KA41.39757168
29LATS11.38177308
30SIK11.36409691
31PAK41.35394273
32PRKD31.34203311
33CDK71.30853838
34DYRK31.28670803
35DDR21.26714023
36TSSK61.19539386
37FGFR41.14534777
38LATS21.13430738
39LRRK21.12572946
40BRD41.11061124
41BMX1.06174731
42PLK41.05818612
43STK101.05709012
44MTOR1.05232049
45PNCK1.04036355
46CHEK11.03443650
47UHMK11.02291455
48PAK20.99319089
49CAMK1D0.99069102
50CLK10.95744353
51TNIK0.95651174
52GRK60.94904263
53TTK0.93578555
54ATR0.90869731
55MAP3K90.90037064
56FGFR10.89660358
57MAP3K80.87051472
58CHEK20.86594973
59STK30.86262607
60CDK20.85092601
61CDK190.84515761
62CASK0.83144821
63ILK0.82891099
64WEE10.82644901
65PLK30.82101268
66CDK11A0.82037754
67PLK10.81951355
68CCNB10.80600105
69KSR10.77014964
70BRAF0.76732292
71CDK150.76644177
72DYRK1B0.76192163
73ATM0.76036462
74MAP4K10.76008533
75RPS6KC10.75453520
76RPS6KL10.75453520
77CDK180.74950485
78AURKB0.74833947
79RIPK10.73370218
80CDK90.72814151
81PIM10.70013895
82RPS6KA20.68388305
83CSNK1A1L0.68333920
84CDK30.67295459
85RPS6KA10.66518929
86CDK140.65879348
87CDK10.64695790
88RPS6KA60.64691293
89BUB10.64518204
90MARK10.62132412
91NTRK10.60840383
92VRK10.60223981
93FGFR20.60108831
94NTRK20.59257613
95IRAK20.57095060
96FGFR30.57089224
97HIPK20.56894611
98BRSK10.56341248
99PDGFRB0.56305488
100YES10.55038492
101DMPK0.54208563
102PRKD20.53145344
103AURKA0.52943508
104AKT20.52644313
105CSNK1G30.50926494
106CSNK1E0.49846675
107EIF2AK20.49755354
108CSNK1G10.49592123
109CDK80.49572741
110STK40.49461029
111TAOK10.49018384
112AKT10.48689548
113SCYL20.47526783
114MAPK140.47335054
115MAP2K20.45097352
116SIK30.44973945
117TTN0.44779842
118CHUK0.44691605
119BCR0.44181782
120ERBB20.42507399
121CAMK1G0.42240193
122MAPK100.41753208
123MAPK90.41673118
124CSNK1D0.41599661
125PRKDC0.41114804
126MELK0.40963829
127DYRK20.38069403
128GSK3B0.38039839
129TAOK20.36586781
130MAPK80.36295331
131MAPK10.36002466

Predicted pathways (KEGG)

RankGene SetZ-score
1Spliceosome_Homo sapiens_hsa030402.76991134
2mRNA surveillance pathway_Homo sapiens_hsa030152.36684241
3DNA replication_Homo sapiens_hsa030302.26670327
4Basal cell carcinoma_Homo sapiens_hsa052172.25133003
5RNA transport_Homo sapiens_hsa030132.13043390
6Cell cycle_Homo sapiens_hsa041102.11339861
7Ribosome_Homo sapiens_hsa030101.98076887
8Mismatch repair_Homo sapiens_hsa034301.96187421
9Hippo signaling pathway_Homo sapiens_hsa043901.85870298
10Chronic myeloid leukemia_Homo sapiens_hsa052201.85627125
11MicroRNAs in cancer_Homo sapiens_hsa052061.82837244
12Colorectal cancer_Homo sapiens_hsa052101.82551865
13Hedgehog signaling pathway_Homo sapiens_hsa043401.73071125
14Base excision repair_Homo sapiens_hsa034101.72903206
15Endometrial cancer_Homo sapiens_hsa052131.63500020
16Notch signaling pathway_Homo sapiens_hsa043301.60705689
17Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.60672160
18Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.45913624
19Adherens junction_Homo sapiens_hsa045201.45814224
20Small cell lung cancer_Homo sapiens_hsa052221.44859156
21Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.44296164
22Wnt signaling pathway_Homo sapiens_hsa043101.39822249
23HTLV-I infection_Homo sapiens_hsa051661.36686651
24Thyroid cancer_Homo sapiens_hsa052161.35722786
25Non-small cell lung cancer_Homo sapiens_hsa052231.33647628
26TGF-beta signaling pathway_Homo sapiens_hsa043501.33163102
27Transcriptional misregulation in cancer_Homo sapiens_hsa052021.31905957
28Nucleotide excision repair_Homo sapiens_hsa034201.31902724
29Proteoglycans in cancer_Homo sapiens_hsa052051.29519362
30Viral myocarditis_Homo sapiens_hsa054161.27942996
31Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.22002727
32Biosynthesis of amino acids_Homo sapiens_hsa012301.20558470
33Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.19520631
34mTOR signaling pathway_Homo sapiens_hsa041501.18138471
35One carbon pool by folate_Homo sapiens_hsa006701.17765452
36Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.17044868
37Prostate cancer_Homo sapiens_hsa052151.16137604
38p53 signaling pathway_Homo sapiens_hsa041151.16018144
39Bladder cancer_Homo sapiens_hsa052191.12583815
40Glioma_Homo sapiens_hsa052141.11915613
41AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.10759418
42Pathways in cancer_Homo sapiens_hsa052001.10634021
43Acute myeloid leukemia_Homo sapiens_hsa052211.10532022
44Pancreatic cancer_Homo sapiens_hsa052121.09856178
45Viral carcinogenesis_Homo sapiens_hsa052031.09395901
46Focal adhesion_Homo sapiens_hsa045101.09020205
47Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.08842051
48Neurotrophin signaling pathway_Homo sapiens_hsa047221.07515565
49RNA degradation_Homo sapiens_hsa030181.07203163
50Axon guidance_Homo sapiens_hsa043601.07174641
51Renal cell carcinoma_Homo sapiens_hsa052111.02116189
52Oocyte meiosis_Homo sapiens_hsa041141.01818781
53Thyroid hormone signaling pathway_Homo sapiens_hsa049190.97376021
54Hepatitis B_Homo sapiens_hsa051610.93307620
55Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.91628420
56Fanconi anemia pathway_Homo sapiens_hsa034600.90852930
57VEGF signaling pathway_Homo sapiens_hsa043700.90510429
58Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.90290426
59Melanoma_Homo sapiens_hsa052180.88758811
60Central carbon metabolism in cancer_Homo sapiens_hsa052300.87881596
61Homologous recombination_Homo sapiens_hsa034400.87822590
62Melanogenesis_Homo sapiens_hsa049160.86714842
63Lysine degradation_Homo sapiens_hsa003100.86313078
64T cell receptor signaling pathway_Homo sapiens_hsa046600.85061255
65Tight junction_Homo sapiens_hsa045300.84760502
66Epstein-Barr virus infection_Homo sapiens_hsa051690.83632357
67Herpes simplex infection_Homo sapiens_hsa051680.83284872
68B cell receptor signaling pathway_Homo sapiens_hsa046620.82288813
69ECM-receptor interaction_Homo sapiens_hsa045120.81896484
70AMPK signaling pathway_Homo sapiens_hsa041520.80821064
71Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.80674827
72Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.80469847
73Prion diseases_Homo sapiens_hsa050200.78370321
74Regulation of actin cytoskeleton_Homo sapiens_hsa048100.77823354
75ErbB signaling pathway_Homo sapiens_hsa040120.77509277
76Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.77413022
77Long-term potentiation_Homo sapiens_hsa047200.74861941
78Antigen processing and presentation_Homo sapiens_hsa046120.74837745
79Rap1 signaling pathway_Homo sapiens_hsa040150.74704695
80Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.74094749
81PI3K-Akt signaling pathway_Homo sapiens_hsa041510.73050216
82Steroid biosynthesis_Homo sapiens_hsa001000.73023020
83Estrogen signaling pathway_Homo sapiens_hsa049150.72689603
84Leukocyte transendothelial migration_Homo sapiens_hsa046700.71977075
85Gap junction_Homo sapiens_hsa045400.71952740
86Shigellosis_Homo sapiens_hsa051310.70955370
87FoxO signaling pathway_Homo sapiens_hsa040680.70354809
88Apoptosis_Homo sapiens_hsa042100.70206953
89MAPK signaling pathway_Homo sapiens_hsa040100.68383287
90Primary immunodeficiency_Homo sapiens_hsa053400.67033079
91Choline metabolism in cancer_Homo sapiens_hsa052310.66892789
92Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.66070897
93Prolactin signaling pathway_Homo sapiens_hsa049170.66036222
94Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.63398580
95Platelet activation_Homo sapiens_hsa046110.63265737
96Dorso-ventral axis formation_Homo sapiens_hsa043200.62816829
97Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.62494357
98Non-homologous end-joining_Homo sapiens_hsa034500.61319962
99Longevity regulating pathway - mammal_Homo sapiens_hsa042110.60686701
100Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.60239463
101Toxoplasmosis_Homo sapiens_hsa051450.59786054
102Alcoholism_Homo sapiens_hsa050340.59057429
103HIF-1 signaling pathway_Homo sapiens_hsa040660.56695223
104Pentose phosphate pathway_Homo sapiens_hsa000300.56312825
105Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.55814253
106Cocaine addiction_Homo sapiens_hsa050300.54777819
107Basal transcription factors_Homo sapiens_hsa030220.54491562
108Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.54437847
109Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.54220750
110Amoebiasis_Homo sapiens_hsa051460.53634019
111Long-term depression_Homo sapiens_hsa047300.52928357
112Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.51867742
113Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.51779900
114Systemic lupus erythematosus_Homo sapiens_hsa053220.50405235
115Measles_Homo sapiens_hsa051620.49474011
116Phospholipase D signaling pathway_Homo sapiens_hsa040720.48063618
117Cysteine and methionine metabolism_Homo sapiens_hsa002700.45782573
118Insulin signaling pathway_Homo sapiens_hsa049100.44517584
1192-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.44442536
120GnRH signaling pathway_Homo sapiens_hsa049120.43806355
121Pyrimidine metabolism_Homo sapiens_hsa002400.43675932
122Vitamin B6 metabolism_Homo sapiens_hsa007500.41416208

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