

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 6.58699191 |
| 2 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.57284899 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.08618421 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 6.08618421 |
| 5 | DNA deamination (GO:0045006) | 5.23135197 |
| 6 | chaperone-mediated protein transport (GO:0072321) | 5.22760909 |
| 7 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.94970161 |
| 8 | proteasome assembly (GO:0043248) | 4.86594400 |
| 9 | maturation of SSU-rRNA (GO:0030490) | 4.22374259 |
| 10 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.10825039 |
| 11 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.10825039 |
| 12 | pseudouridine synthesis (GO:0001522) | 4.10385505 |
| 13 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.96883797 |
| 14 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 3.90474930 |
| 15 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.85615588 |
| 16 | ATP biosynthetic process (GO:0006754) | 3.83648489 |
| 17 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.81191181 |
| 18 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 3.76482195 |
| 19 | respiratory electron transport chain (GO:0022904) | 3.75738046 |
| 20 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.74556200 |
| 21 | GTP biosynthetic process (GO:0006183) | 3.73409705 |
| 22 | electron transport chain (GO:0022900) | 3.73408292 |
| 23 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.64881909 |
| 24 | protein neddylation (GO:0045116) | 3.63053902 |
| 25 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.54892008 |
| 26 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 3.53768368 |
| 27 | platelet dense granule organization (GO:0060155) | 3.49542706 |
| 28 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.45902531 |
| 29 | NADH dehydrogenase complex assembly (GO:0010257) | 3.45902531 |
| 30 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.45902531 |
| 31 | protein complex biogenesis (GO:0070271) | 3.39129148 |
| 32 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.33534866 |
| 33 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.33044863 |
| 34 | UTP biosynthetic process (GO:0006228) | 3.31586274 |
| 35 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.31492806 |
| 36 | negative regulation of ligase activity (GO:0051352) | 3.31492806 |
| 37 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.31390112 |
| 38 | ribosome assembly (GO:0042255) | 3.28577879 |
| 39 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.27664723 |
| 40 | UTP metabolic process (GO:0046051) | 3.25406238 |
| 41 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.23104678 |
| 42 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.21588444 |
| 43 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.21095181 |
| 44 | ribosomal large subunit biogenesis (GO:0042273) | 3.20607337 |
| 45 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.20003325 |
| 46 | rRNA modification (GO:0000154) | 3.19142282 |
| 47 | regulation of hypersensitivity (GO:0002883) | 3.16901824 |
| 48 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.15939597 |
| 49 | purine nucleoside monophosphate biosynthetic process (GO:0009127) | 3.08984814 |
| 50 | purine ribonucleoside monophosphate biosynthetic process (GO:0009168) | 3.08984814 |
| 51 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.05661723 |
| 52 | protein peptidyl-prolyl isomerization (GO:0000413) | 3.05631425 |
| 53 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.05316542 |
| 54 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.05316542 |
| 55 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.05316542 |
| 56 | tRNA processing (GO:0008033) | 3.01118267 |
| 57 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.00734573 |
| 58 | intracellular protein transmembrane import (GO:0044743) | 2.99852183 |
| 59 | mannosylation (GO:0097502) | 2.99848571 |
| 60 | piRNA metabolic process (GO:0034587) | 2.97671687 |
| 61 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.96413923 |
| 62 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.96413923 |
| 63 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.96115745 |
| 64 | protein-cofactor linkage (GO:0018065) | 2.94968366 |
| 65 | protein deneddylation (GO:0000338) | 2.93401968 |
| 66 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.92867201 |
| 67 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.92867201 |
| 68 | prenylation (GO:0097354) | 2.92458828 |
| 69 | protein prenylation (GO:0018342) | 2.92458828 |
| 70 | base-excision repair, AP site formation (GO:0006285) | 2.91732478 |
| 71 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.90836199 |
| 72 | nucleoside triphosphate biosynthetic process (GO:0009142) | 2.89894532 |
| 73 | positive regulation of defense response to virus by host (GO:0002230) | 2.89770524 |
| 74 | rRNA methylation (GO:0031167) | 2.89214645 |
| 75 | hydrogen ion transmembrane transport (GO:1902600) | 2.88091389 |
| 76 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.88088453 |
| 77 | cullin deneddylation (GO:0010388) | 2.85653069 |
| 78 | ribosomal small subunit assembly (GO:0000028) | 2.81853016 |
| 79 | cellular component biogenesis (GO:0044085) | 2.80053786 |
| 80 | cytidine deamination (GO:0009972) | 2.76741867 |
| 81 | cytidine metabolic process (GO:0046087) | 2.76741867 |
| 82 | cytidine catabolic process (GO:0006216) | 2.76741867 |
| 83 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.75070780 |
| 84 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.75023800 |
| 85 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.72516317 |
| 86 | termination of RNA polymerase III transcription (GO:0006386) | 2.72511910 |
| 87 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.72511910 |
| 88 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.70113871 |
| 89 | fucose catabolic process (GO:0019317) | 2.70077622 |
| 90 | L-fucose metabolic process (GO:0042354) | 2.70077622 |
| 91 | L-fucose catabolic process (GO:0042355) | 2.70077622 |
| 92 | transcription from mitochondrial promoter (GO:0006390) | 2.69721974 |
| 93 | positive regulation of ligase activity (GO:0051351) | 2.69160403 |
| 94 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.68239001 |
| 95 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.68239001 |
| 96 | cellular ketone body metabolic process (GO:0046950) | 2.67809491 |
| 97 | proton transport (GO:0015992) | 2.64423788 |
| 98 | tRNA metabolic process (GO:0006399) | 2.63040750 |
| 99 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.61446680 |
| 100 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.61446680 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.03487736 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.47031678 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.19897617 |
| 4 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.31103492 |
| 5 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.19183127 |
| 6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.07424138 |
| 7 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.83790740 |
| 8 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.80000334 |
| 9 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.70286294 |
| 10 | VDR_22108803_ChIP-Seq_LS180_Human | 2.68423461 |
| 11 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.59584633 |
| 12 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.53676651 |
| 13 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.42878292 |
| 14 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.37714890 |
| 15 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.36273124 |
| 16 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.22334090 |
| 17 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.19368920 |
| 18 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.11703374 |
| 19 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.09522434 |
| 20 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.07330959 |
| 21 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.06814088 |
| 22 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.89759434 |
| 23 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.88905420 |
| 24 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.86049421 |
| 25 | EWS_26573619_Chip-Seq_HEK293_Human | 1.74765723 |
| 26 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.70970668 |
| 27 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.70312778 |
| 28 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.68774842 |
| 29 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.68689258 |
| 30 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.68219908 |
| 31 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.66176337 |
| 32 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.65864219 |
| 33 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.63749225 |
| 34 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.56595751 |
| 35 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.55293522 |
| 36 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.55276825 |
| 37 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.54370849 |
| 38 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.49599807 |
| 39 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.49532679 |
| 40 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.45097105 |
| 41 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.44621931 |
| 42 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.44320345 |
| 43 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.42820549 |
| 44 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.41770811 |
| 45 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.38087869 |
| 46 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.37785614 |
| 47 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.36274722 |
| 48 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.34513612 |
| 49 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.33988175 |
| 50 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.30509851 |
| 51 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.27102966 |
| 52 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.26285536 |
| 53 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.25735230 |
| 54 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.25142133 |
| 55 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.25142133 |
| 56 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.24967245 |
| 57 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.24340597 |
| 58 | P300_19829295_ChIP-Seq_ESCs_Human | 1.24204688 |
| 59 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.22566591 |
| 60 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.17799995 |
| 61 | NCOR_22424771_ChIP-Seq_293T_Human | 1.17355872 |
| 62 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.16864492 |
| 63 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.16550757 |
| 64 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.16485184 |
| 65 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.16394234 |
| 66 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.14567320 |
| 67 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.14477473 |
| 68 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.14431389 |
| 69 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.14431389 |
| 70 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.13598813 |
| 71 | GATA3_26560356_Chip-Seq_TH2_Human | 1.13464843 |
| 72 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.12578375 |
| 73 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.10830944 |
| 74 | RBPJ_21746931_ChIP-Seq_IB4_Human | 1.08960625 |
| 75 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.08493836 |
| 76 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.07667940 |
| 77 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.05911159 |
| 78 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.05068376 |
| 79 | AR_20517297_ChIP-Seq_VCAP_Human | 1.03857855 |
| 80 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.03758661 |
| 81 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.02380785 |
| 82 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.00365279 |
| 83 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.99719257 |
| 84 | E2F7_22180533_ChIP-Seq_HELA_Human | 0.99685236 |
| 85 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.99577224 |
| 86 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.98394259 |
| 87 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.98160618 |
| 88 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.97491803 |
| 89 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.97328772 |
| 90 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.96819823 |
| 91 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.96176475 |
| 92 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.95471114 |
| 93 | MYB_26560356_Chip-Seq_TH2_Human | 0.95433871 |
| 94 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.93584160 |
| 95 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.93380251 |
| 96 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.92931768 |
| 97 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.92472632 |
| 98 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.92461366 |
| 99 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.92258611 |
| 100 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.92227177 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005377_hearing/vestibular/ear_phenot | 3.88795674 |
| 2 | MP0003878_abnormal_ear_physiology | 3.88795674 |
| 3 | MP0003786_premature_aging | 3.27047557 |
| 4 | MP0008877_abnormal_DNA_methylation | 3.21813860 |
| 5 | MP0005671_abnormal_response_to | 3.14696593 |
| 6 | MP0003195_calcinosis | 3.03622571 |
| 7 | MP0002102_abnormal_ear_morphology | 2.72889534 |
| 8 | MP0004147_increased_porphyrin_level | 2.70827622 |
| 9 | MP0005084_abnormal_gallbladder_morpholo | 2.44356112 |
| 10 | MP0006292_abnormal_olfactory_placode | 2.41754032 |
| 11 | MP0003693_abnormal_embryo_hatching | 2.39769666 |
| 12 | MP0004957_abnormal_blastocyst_morpholog | 2.34496801 |
| 13 | MP0009379_abnormal_foot_pigmentation | 2.22330277 |
| 14 | MP0009785_altered_susceptibility_to | 2.21647630 |
| 15 | MP0008995_early_reproductive_senescence | 2.08449571 |
| 16 | MP0010094_abnormal_chromosome_stability | 2.08158866 |
| 17 | MP0006072_abnormal_retinal_apoptosis | 1.91858009 |
| 18 | MP0003787_abnormal_imprinting | 1.87245312 |
| 19 | MP0004145_abnormal_muscle_electrophysio | 1.87129034 |
| 20 | MP0003567_abnormal_fetal_cardiomyocyte | 1.84316206 |
| 21 | MP0008872_abnormal_physiological_respon | 1.79934068 |
| 22 | MP0008058_abnormal_DNA_repair | 1.79816004 |
| 23 | MP0001485_abnormal_pinna_reflex | 1.73306069 |
| 24 | MP0000685_abnormal_immune_system | 1.61599895 |
| 25 | MP0001835_abnormal_antigen_presentation | 1.55619344 |
| 26 | MP0005551_abnormal_eye_electrophysiolog | 1.55228990 |
| 27 | MP0008875_abnormal_xenobiotic_pharmacok | 1.48121480 |
| 28 | MP0001800_abnormal_humoral_immune | 1.46224657 |
| 29 | MP0002876_abnormal_thyroid_physiology | 1.44386453 |
| 30 | MP0008961_abnormal_basal_metabolism | 1.41941878 |
| 31 | MP0003646_muscle_fatigue | 1.41444722 |
| 32 | MP0002736_abnormal_nociception_after | 1.38273461 |
| 33 | MP0001919_abnormal_reproductive_system | 1.37850646 |
| 34 | MP0003111_abnormal_nucleus_morphology | 1.36648833 |
| 35 | MP0001661_extended_life_span | 1.34830784 |
| 36 | MP0005365_abnormal_bile_salt | 1.30228410 |
| 37 | MP0006054_spinal_hemorrhage | 1.28323493 |
| 38 | MP0005253_abnormal_eye_physiology | 1.26977747 |
| 39 | MP0002751_abnormal_autonomic_nervous | 1.26695298 |
| 40 | MP0004043_abnormal_pH_regulation | 1.20026214 |
| 41 | MP0002277_abnormal_respiratory_mucosa | 1.16726903 |
| 42 | MP0003724_increased_susceptibility_to | 1.14407981 |
| 43 | MP0008007_abnormal_cellular_replicative | 1.13889998 |
| 44 | MP0005389_reproductive_system_phenotype | 1.12834480 |
| 45 | MP0009333_abnormal_splenocyte_physiolog | 1.12257823 |
| 46 | MP0000647_abnormal_sebaceous_gland | 1.11687606 |
| 47 | MP0003718_maternal_effect | 1.11451668 |
| 48 | MP0004142_abnormal_muscle_tone | 1.10531185 |
| 49 | MP0001501_abnormal_sleep_pattern | 1.08943484 |
| 50 | MP0004133_heterotaxia | 1.08719239 |
| 51 | MP0001529_abnormal_vocalization | 1.06008974 |
| 52 | MP0005000_abnormal_immune_tolerance | 1.03613128 |
| 53 | MP0002090_abnormal_vision | 0.98014870 |
| 54 | MP0002163_abnormal_gland_morphology | 0.96916092 |
| 55 | MP0006036_abnormal_mitochondrial_physio | 0.96200389 |
| 56 | MP0001765_abnormal_ion_homeostasis | 0.95793250 |
| 57 | MP0002006_tumorigenesis | 0.94603328 |
| 58 | MP0000372_irregular_coat_pigmentation | 0.93580304 |
| 59 | MP0008789_abnormal_olfactory_epithelium | 0.93225294 |
| 60 | MP0002723_abnormal_immune_serum | 0.91007388 |
| 61 | MP0006035_abnormal_mitochondrial_morpho | 0.91003958 |
| 62 | MP0002138_abnormal_hepatobiliary_system | 0.90818964 |
| 63 | MP0005379_endocrine/exocrine_gland_phen | 0.90739786 |
| 64 | MP0003806_abnormal_nucleotide_metabolis | 0.90535014 |
| 65 | MP0003186_abnormal_redox_activity | 0.89405524 |
| 66 | MP0005387_immune_system_phenotype | 0.86759986 |
| 67 | MP0001790_abnormal_immune_system | 0.86759986 |
| 68 | MP0001873_stomach_inflammation | 0.85844941 |
| 69 | MP0005646_abnormal_pituitary_gland | 0.85762165 |
| 70 | MP0002452_abnormal_antigen_presenting | 0.85506659 |
| 71 | MP0001188_hyperpigmentation | 0.85494387 |
| 72 | MP0001293_anophthalmia | 0.83920264 |
| 73 | MP0004742_abnormal_vestibular_system | 0.83463822 |
| 74 | MP0005085_abnormal_gallbladder_physiolo | 0.83130446 |
| 75 | MP0002420_abnormal_adaptive_immunity | 0.82878620 |
| 76 | MP0001819_abnormal_immune_cell | 0.81356968 |
| 77 | MP0002166_altered_tumor_susceptibility | 0.80177231 |
| 78 | MP0002148_abnormal_hypersensitivity_rea | 0.80166382 |
| 79 | MP0000689_abnormal_spleen_morphology | 0.79939274 |
| 80 | MP0002272_abnormal_nervous_system | 0.79872975 |
| 81 | MP0009764_decreased_sensitivity_to | 0.79738305 |
| 82 | MP0005645_abnormal_hypothalamus_physiol | 0.79080252 |
| 83 | MP0008932_abnormal_embryonic_tissue | 0.78605382 |
| 84 | MP0000631_abnormal_neuroendocrine_gland | 0.78537873 |
| 85 | MP0002398_abnormal_bone_marrow | 0.78274862 |
| 86 | MP0003959_abnormal_lean_body | 0.77740527 |
| 87 | MP0001764_abnormal_homeostasis | 0.77479950 |
| 88 | MP0003763_abnormal_thymus_physiology | 0.77064304 |
| 89 | MP0003011_delayed_dark_adaptation | 0.77051624 |
| 90 | MP0001119_abnormal_female_reproductive | 0.76620510 |
| 91 | MP0005410_abnormal_fertilization | 0.75524306 |
| 92 | MP0001968_abnormal_touch/_nociception | 0.75266903 |
| 93 | MP0001929_abnormal_gametogenesis | 0.74708954 |
| 94 | MP0000716_abnormal_immune_system | 0.74069859 |
| 95 | MP0002210_abnormal_sex_determination | 0.73866795 |
| 96 | MP0005075_abnormal_melanosome_morpholog | 0.73069922 |
| 97 | MP0003638_abnormal_response/metabolism_ | 0.72324236 |
| 98 | MP0001845_abnormal_inflammatory_respons | 0.71711596 |
| 99 | MP0000703_abnormal_thymus_morphology | 0.71119629 |
| 100 | MP0004019_abnormal_vitamin_homeostasis | 0.69704972 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Hepatocellular necrosis (HP:0001404) | 4.39185266 |
| 2 | Increased hepatocellular lipid droplets (HP:0006565) | 4.34143175 |
| 3 | Lipid accumulation in hepatocytes (HP:0006561) | 4.20753979 |
| 4 | Mitochondrial inheritance (HP:0001427) | 4.05343768 |
| 5 | Increased CSF lactate (HP:0002490) | 3.96355481 |
| 6 | IgG deficiency (HP:0004315) | 3.92415490 |
| 7 | Hepatic necrosis (HP:0002605) | 3.88547700 |
| 8 | Renal Fanconi syndrome (HP:0001994) | 3.65136080 |
| 9 | Acute necrotizing encephalopathy (HP:0006965) | 3.65029691 |
| 10 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.34225248 |
| 11 | Absent/shortened dynein arms (HP:0200106) | 3.34225248 |
| 12 | Acute encephalopathy (HP:0006846) | 3.32377573 |
| 13 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.15031827 |
| 14 | Hypoproteinemia (HP:0003075) | 3.12183797 |
| 15 | Azoospermia (HP:0000027) | 3.05263617 |
| 16 | Increased serum lactate (HP:0002151) | 3.04208650 |
| 17 | 3-Methylglutaconic aciduria (HP:0003535) | 3.03225108 |
| 18 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.02929373 |
| 19 | Increased serum pyruvate (HP:0003542) | 2.99626681 |
| 20 | Testicular atrophy (HP:0000029) | 2.96112953 |
| 21 | Progressive macrocephaly (HP:0004481) | 2.95306049 |
| 22 | Congenital, generalized hypertrichosis (HP:0004540) | 2.93540983 |
| 23 | Exertional dyspnea (HP:0002875) | 2.83254113 |
| 24 | Abolished electroretinogram (ERG) (HP:0000550) | 2.79291655 |
| 25 | Brittle hair (HP:0002299) | 2.77096028 |
| 26 | Methylmalonic acidemia (HP:0002912) | 2.70976123 |
| 27 | Congenital stationary night blindness (HP:0007642) | 2.67283019 |
| 28 | Thyroid-stimulating hormone excess (HP:0002925) | 2.67048132 |
| 29 | CNS demyelination (HP:0007305) | 2.67028340 |
| 30 | Aplastic anemia (HP:0001915) | 2.65849921 |
| 31 | Hyperglycinemia (HP:0002154) | 2.61735710 |
| 32 | Cerebral edema (HP:0002181) | 2.58947955 |
| 33 | Pancytopenia (HP:0001876) | 2.57451970 |
| 34 | Type I transferrin isoform profile (HP:0003642) | 2.57399207 |
| 35 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.54587488 |
| 36 | Supernumerary spleens (HP:0009799) | 2.53075390 |
| 37 | Abnormal spermatogenesis (HP:0008669) | 2.43595829 |
| 38 | Glycosuria (HP:0003076) | 2.43319078 |
| 39 | Abnormality of urine glucose concentration (HP:0011016) | 2.43319078 |
| 40 | Increased intramyocellular lipid droplets (HP:0012240) | 2.40029922 |
| 41 | Severe combined immunodeficiency (HP:0004430) | 2.38771483 |
| 42 | Microvesicular hepatic steatosis (HP:0001414) | 2.37264482 |
| 43 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.34129549 |
| 44 | Lactic acidosis (HP:0003128) | 2.33383687 |
| 45 | Abnormality of glycolysis (HP:0004366) | 2.29586517 |
| 46 | Parakeratosis (HP:0001036) | 2.28943360 |
| 47 | Constricted visual fields (HP:0001133) | 2.27202168 |
| 48 | Methylmalonic aciduria (HP:0012120) | 2.25788747 |
| 49 | Optic disc pallor (HP:0000543) | 2.24143645 |
| 50 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.23838469 |
| 51 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.23838469 |
| 52 | Abnormal protein glycosylation (HP:0012346) | 2.23838469 |
| 53 | Abnormal glycosylation (HP:0012345) | 2.23838469 |
| 54 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.19782913 |
| 55 | Reticulocytopenia (HP:0001896) | 2.18340561 |
| 56 | Progressive inability to walk (HP:0002505) | 2.17742755 |
| 57 | Generalized aminoaciduria (HP:0002909) | 2.15275309 |
| 58 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.14358787 |
| 59 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.14358787 |
| 60 | Abnormality of methionine metabolism (HP:0010901) | 2.12716571 |
| 61 | Abnormality of the labia minora (HP:0012880) | 2.11567699 |
| 62 | Respiratory failure (HP:0002878) | 2.11026406 |
| 63 | Large eyes (HP:0001090) | 2.10366845 |
| 64 | Hyperphosphaturia (HP:0003109) | 2.09569895 |
| 65 | Respiratory difficulties (HP:0002880) | 2.09533533 |
| 66 | T lymphocytopenia (HP:0005403) | 2.09346771 |
| 67 | Hypomagnesemia (HP:0002917) | 2.09275305 |
| 68 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 2.08235270 |
| 69 | Premature ovarian failure (HP:0008209) | 2.06397793 |
| 70 | Dyschromatopsia (HP:0007641) | 2.04679747 |
| 71 | Pancreatic cysts (HP:0001737) | 2.02732366 |
| 72 | Macrocytic anemia (HP:0001972) | 2.01800617 |
| 73 | Increased muscle lipid content (HP:0009058) | 2.01428128 |
| 74 | Hypoplasia of the uterus (HP:0000013) | 1.99120746 |
| 75 | Leukodystrophy (HP:0002415) | 1.98826507 |
| 76 | Renal cortical cysts (HP:0000803) | 1.97442117 |
| 77 | Chronic sinusitis (HP:0011109) | 1.97239343 |
| 78 | Lethargy (HP:0001254) | 1.96182955 |
| 79 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.94981364 |
| 80 | Increased IgM level (HP:0003496) | 1.93180538 |
| 81 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.92481458 |
| 82 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.92328544 |
| 83 | Abnormality of glycine metabolism (HP:0010895) | 1.92328544 |
| 84 | Abnormality of renal resorption (HP:0011038) | 1.90508389 |
| 85 | Abnormality of serum amino acid levels (HP:0003112) | 1.90012649 |
| 86 | Pancreatic fibrosis (HP:0100732) | 1.88834581 |
| 87 | Combined immunodeficiency (HP:0005387) | 1.87883535 |
| 88 | Emotional lability (HP:0000712) | 1.86864066 |
| 89 | Stomatitis (HP:0010280) | 1.86365817 |
| 90 | Abnormality of T cell number (HP:0011839) | 1.85848046 |
| 91 | Opisthotonus (HP:0002179) | 1.83341544 |
| 92 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 1.81187801 |
| 93 | Adrenal hypoplasia (HP:0000835) | 1.80387271 |
| 94 | Type 2 muscle fiber atrophy (HP:0003554) | 1.78706413 |
| 95 | Abnormality of magnesium homeostasis (HP:0004921) | 1.78148141 |
| 96 | Colon cancer (HP:0003003) | 1.77749982 |
| 97 | Exercise intolerance (HP:0003546) | 1.76406686 |
| 98 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.76319481 |
| 99 | Thyroiditis (HP:0100646) | 1.76028445 |
| 100 | Abnormal number of erythroid precursors (HP:0012131) | 1.75519135 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ZAK | 4.91023443 |
| 2 | TXK | 4.77929275 |
| 3 | BUB1 | 4.45690505 |
| 4 | TLK1 | 4.44730830 |
| 5 | SCYL2 | 2.77062788 |
| 6 | TRIM28 | 2.72859330 |
| 7 | VRK2 | 2.64814364 |
| 8 | TIE1 | 2.43558308 |
| 9 | VRK1 | 2.39304861 |
| 10 | NUAK1 | 2.28855500 |
| 11 | TSSK6 | 2.05351689 |
| 12 | NME1 | 1.99968783 |
| 13 | GRK1 | 1.99536423 |
| 14 | MAP3K12 | 1.79749413 |
| 15 | MKNK1 | 1.78391115 |
| 16 | PLK3 | 1.72610077 |
| 17 | TAOK3 | 1.69344076 |
| 18 | STK16 | 1.60139390 |
| 19 | WNK4 | 1.58702824 |
| 20 | ADRBK2 | 1.51454663 |
| 21 | KDR | 1.50079779 |
| 22 | MKNK2 | 1.47592514 |
| 23 | TEC | 1.38772432 |
| 24 | MST4 | 1.35309029 |
| 25 | GRK6 | 1.33672906 |
| 26 | PBK | 1.27503579 |
| 27 | CDC7 | 1.26702141 |
| 28 | TAF1 | 1.13428637 |
| 29 | OXSR1 | 1.12450682 |
| 30 | BMPR2 | 1.11572054 |
| 31 | EIF2AK3 | 1.11313161 |
| 32 | TRPM7 | 1.08741740 |
| 33 | MAP4K1 | 1.07084539 |
| 34 | ALK | 1.04531323 |
| 35 | PDK2 | 1.01149257 |
| 36 | TNIK | 1.00336077 |
| 37 | ERBB3 | 0.98169177 |
| 38 | CDK19 | 0.86096246 |
| 39 | NEK1 | 0.85273361 |
| 40 | EIF2AK2 | 0.83052775 |
| 41 | DYRK2 | 0.80428715 |
| 42 | SRPK1 | 0.80105991 |
| 43 | PLK1 | 0.79333875 |
| 44 | AURKB | 0.75375965 |
| 45 | BCKDK | 0.72978191 |
| 46 | TESK2 | 0.72571634 |
| 47 | ITK | 0.72005248 |
| 48 | FES | 0.70868959 |
| 49 | RPS6KA4 | 0.70180766 |
| 50 | IKBKB | 0.69491288 |
| 51 | MYLK | 0.67596655 |
| 52 | EPHA4 | 0.66735594 |
| 53 | IKBKE | 0.65924999 |
| 54 | PHKG1 | 0.63825972 |
| 55 | PHKG2 | 0.63825972 |
| 56 | STK38L | 0.62020806 |
| 57 | TTK | 0.59387095 |
| 58 | IGF1R | 0.57859843 |
| 59 | PASK | 0.57733513 |
| 60 | STK39 | 0.57669886 |
| 61 | NEK2 | 0.53903967 |
| 62 | ATR | 0.53477344 |
| 63 | PIM1 | 0.52730168 |
| 64 | SYK | 0.52492701 |
| 65 | RPS6KA5 | 0.51864923 |
| 66 | WNK3 | 0.51147684 |
| 67 | DAPK1 | 0.50669879 |
| 68 | DAPK3 | 0.50152303 |
| 69 | CDK3 | 0.49868786 |
| 70 | MAPKAPK5 | 0.49789736 |
| 71 | MAP2K2 | 0.49547208 |
| 72 | INSRR | 0.47838074 |
| 73 | MAPKAPK3 | 0.45632507 |
| 74 | BTK | 0.45627742 |
| 75 | SIK3 | 0.44277649 |
| 76 | TBK1 | 0.43469041 |
| 77 | RPS6KB2 | 0.43024129 |
| 78 | LYN | 0.42518330 |
| 79 | CSNK2A1 | 0.42315725 |
| 80 | BCR | 0.40634576 |
| 81 | FRK | 0.39985375 |
| 82 | CSNK1G3 | 0.38885549 |
| 83 | PLK4 | 0.38861276 |
| 84 | CHEK2 | 0.37441092 |
| 85 | CSNK1G1 | 0.34346794 |
| 86 | CSNK2A2 | 0.34340284 |
| 87 | PLK2 | 0.33828843 |
| 88 | LCK | 0.33078732 |
| 89 | CSNK1A1L | 0.32817163 |
| 90 | BMPR1B | 0.31188918 |
| 91 | ATM | 0.30618748 |
| 92 | PRKCQ | 0.30448978 |
| 93 | CCNB1 | 0.30145035 |
| 94 | CHEK1 | 0.29264419 |
| 95 | PRKCI | 0.29036299 |
| 96 | MINK1 | 0.26852028 |
| 97 | MAP3K14 | 0.26841058 |
| 98 | WNK1 | 0.26383515 |
| 99 | PRKCA | 0.24195807 |
| 100 | CSNK1A1 | 0.23173590 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.49372125 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.71975853 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.01905496 |
| 4 | Protein export_Homo sapiens_hsa03060 | 2.75334208 |
| 5 | Ribosome_Homo sapiens_hsa03010 | 2.46092059 |
| 6 | Homologous recombination_Homo sapiens_hsa03440 | 2.42830509 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.34571015 |
| 8 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.17919507 |
| 9 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.17362649 |
| 10 | Huntingtons disease_Homo sapiens_hsa05016 | 2.00787689 |
| 11 | DNA replication_Homo sapiens_hsa03030 | 1.90451922 |
| 12 | Alzheimers disease_Homo sapiens_hsa05010 | 1.89572543 |
| 13 | Asthma_Homo sapiens_hsa05310 | 1.86624863 |
| 14 | Mismatch repair_Homo sapiens_hsa03430 | 1.83860499 |
| 15 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.82174140 |
| 16 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.81929495 |
| 17 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.81766957 |
| 18 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.79181961 |
| 19 | RNA degradation_Homo sapiens_hsa03018 | 1.73451859 |
| 20 | Spliceosome_Homo sapiens_hsa03040 | 1.68884923 |
| 21 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.61935665 |
| 22 | Base excision repair_Homo sapiens_hsa03410 | 1.61546714 |
| 23 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.60280894 |
| 24 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.56202397 |
| 25 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.52898332 |
| 26 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.50687372 |
| 27 | Basal transcription factors_Homo sapiens_hsa03022 | 1.49794628 |
| 28 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.48209056 |
| 29 | RNA transport_Homo sapiens_hsa03013 | 1.47037849 |
| 30 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.45994048 |
| 31 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.44954200 |
| 32 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.39849212 |
| 33 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.32685464 |
| 34 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.27204286 |
| 35 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.26749950 |
| 36 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.26103600 |
| 37 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.24930454 |
| 38 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.20945103 |
| 39 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.13483408 |
| 40 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.12171857 |
| 41 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.11853872 |
| 42 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.10904995 |
| 43 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.10524896 |
| 44 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.10437628 |
| 45 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.10189155 |
| 46 | Allograft rejection_Homo sapiens_hsa05330 | 1.08973693 |
| 47 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.06140497 |
| 48 | Phototransduction_Homo sapiens_hsa04744 | 1.05630412 |
| 49 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.04659639 |
| 50 | Purine metabolism_Homo sapiens_hsa00230 | 1.04354414 |
| 51 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.98100691 |
| 52 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.94300822 |
| 53 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.91424900 |
| 54 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.90554823 |
| 55 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.90510763 |
| 56 | Peroxisome_Homo sapiens_hsa04146 | 0.87541640 |
| 57 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.80105959 |
| 58 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.77863898 |
| 59 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.76750615 |
| 60 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.72559836 |
| 61 | Sulfur relay system_Homo sapiens_hsa04122 | 0.72182804 |
| 62 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.71510085 |
| 63 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.68148583 |
| 64 | Metabolic pathways_Homo sapiens_hsa01100 | 0.65205256 |
| 65 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.64827910 |
| 66 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.61000863 |
| 67 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.54501288 |
| 68 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.52169217 |
| 69 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.49845719 |
| 70 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.49803373 |
| 71 | Viral myocarditis_Homo sapiens_hsa05416 | 0.48567213 |
| 72 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.48281868 |
| 73 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.47788037 |
| 74 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.46873400 |
| 75 | Cell cycle_Homo sapiens_hsa04110 | 0.45632698 |
| 76 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.45543136 |
| 77 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.45494628 |
| 78 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.43512118 |
| 79 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.42448963 |
| 80 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.40287219 |
| 81 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.39808237 |
| 82 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.39093751 |
| 83 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.38639409 |
| 84 | Olfactory transduction_Homo sapiens_hsa04740 | 0.38600286 |
| 85 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.37969842 |
| 86 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.35639234 |
| 87 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.35242949 |
| 88 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.34364085 |
| 89 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.33700651 |
| 90 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.33076700 |
| 91 | Retinol metabolism_Homo sapiens_hsa00830 | 0.32472075 |
| 92 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.32249725 |
| 93 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.31224887 |
| 94 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.30834234 |
| 95 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.30642535 |
| 96 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.30501569 |
| 97 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.30037786 |
| 98 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.29052489 |
| 99 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.26996034 |
| 100 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.26887670 |

