HNRNPA1P14

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1establishment of protein localization to mitochondrial membrane (GO:0090151)4.49184706
2mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.27029322
3proteasome assembly (GO:0043248)4.03144875
4exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 4.01140720
5protein neddylation (GO:0045116)4.00884877
6nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.96757765
7DNA double-strand break processing (GO:0000729)3.90660477
8replication fork processing (GO:0031297)3.89321315
9energy coupled proton transport, down electrochemical gradient (GO:0015985)3.89215958
10ATP synthesis coupled proton transport (GO:0015986)3.89215958
11histone mRNA metabolic process (GO:0008334)3.51405948
12purine nucleobase biosynthetic process (GO:0009113)3.49234748
13DNA deamination (GO:0045006)3.48892940
14tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.44261256
15RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.44261256
16DNA catabolic process, exonucleolytic (GO:0000738)3.40122815
17protein prenylation (GO:0018342)3.36227628
18prenylation (GO:0097354)3.36227628
19negative regulation of DNA-dependent DNA replication (GO:2000104)3.36067313
20regulation of DNA endoreduplication (GO:0032875)3.31001996
21chromatin remodeling at centromere (GO:0031055)3.30076951
22rRNA modification (GO:0000154)3.29840133
23mismatch repair (GO:0006298)3.27489012
24CENP-A containing nucleosome assembly (GO:0034080)3.27084868
25transcription elongation from RNA polymerase I promoter (GO:0006362)3.26993697
26mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.26647018
27mitochondrial respiratory chain complex I assembly (GO:0032981)3.26647018
28NADH dehydrogenase complex assembly (GO:0010257)3.26647018
29spliceosomal snRNP assembly (GO:0000387)3.24369066
30nucleobase biosynthetic process (GO:0046112)3.21652367
31RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.20427995
32termination of RNA polymerase I transcription (GO:0006363)3.18651561
33IMP biosynthetic process (GO:0006188)3.18257860
34regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.15519492
35regulation of mitotic spindle checkpoint (GO:1903504)3.15519492
36platelet dense granule organization (GO:0060155)3.15039203
37recombinational repair (GO:0000725)3.11871979
38negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.10361177
39double-strand break repair via homologous recombination (GO:0000724)3.10042204
40somite development (GO:0061053)3.07351103
41histone H2A acetylation (GO:0043968)3.06099300
42DNA replication-dependent nucleosome assembly (GO:0006335)3.05503208
43DNA replication-dependent nucleosome organization (GO:0034723)3.05503208
44DNA damage response, detection of DNA damage (GO:0042769)3.04712648
45otic vesicle formation (GO:0030916)3.03681353
46protein complex biogenesis (GO:0070271)3.03654387
47telomere maintenance via semi-conservative replication (GO:0032201)3.00443285
48gonadal mesoderm development (GO:0007506)2.97848203
49rRNA methylation (GO:0031167)2.96359255
50water-soluble vitamin biosynthetic process (GO:0042364)2.95142375
51postreplication repair (GO:0006301)2.94074522
52DNA-templated transcription, termination (GO:0006353)2.91949249
53histone exchange (GO:0043486)2.89215411
54termination of RNA polymerase II transcription (GO:0006369)2.88831984
55maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.87937493
56regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.86065498
57ribosome assembly (GO:0042255)2.85142616
58regulation of centriole replication (GO:0046599)2.84436129
59somatic hypermutation of immunoglobulin genes (GO:0016446)2.84248552
60somatic diversification of immune receptors via somatic mutation (GO:0002566)2.84248552
61DNA ligation (GO:0006266)2.83432460
62cullin deneddylation (GO:0010388)2.82378658
63positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.81751044
64signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.81289031
65signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.81289031
66signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.81289031
67mitochondrial respiratory chain complex assembly (GO:0033108)2.78439372
68mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.78433595
69establishment of integrated proviral latency (GO:0075713)2.78199082
70DNA strand elongation involved in DNA replication (GO:0006271)2.77181788
71DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.75285696
72regulation of nuclear cell cycle DNA replication (GO:0033262)2.74807397
73termination of RNA polymerase III transcription (GO:0006386)2.73933383
74transcription elongation from RNA polymerase III promoter (GO:0006385)2.73933383
75regulation of cellular amino acid metabolic process (GO:0006521)2.73471036
76chaperone-mediated protein transport (GO:0072321)2.70999828
77signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.70733084
78intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.70733084
79spliceosomal complex assembly (GO:0000245)2.70426718
80negative regulation of ligase activity (GO:0051352)2.69684533
81negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.69684533
82protein-cofactor linkage (GO:0018065)2.68485051
83signal transduction involved in cell cycle checkpoint (GO:0072395)2.66403083
84kinetochore assembly (GO:0051382)2.66129866
85anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.66034865
86signal transduction involved in DNA damage checkpoint (GO:0072422)2.65140979
87signal transduction involved in DNA integrity checkpoint (GO:0072401)2.65140979
88intra-S DNA damage checkpoint (GO:0031573)2.64976480
89kinetochore organization (GO:0051383)2.64093997
90synapsis (GO:0007129)2.63746636
91microtubule depolymerization (GO:0007019)2.62552590
92intraciliary transport (GO:0042073)2.62463659
93telomere maintenance via recombination (GO:0000722)2.61744594
94mitotic recombination (GO:0006312)2.60037076
95replicative senescence (GO:0090399)2.59692873
96nucleotide-excision repair, DNA gap filling (GO:0006297)2.58773982
97DNA replication-independent nucleosome organization (GO:0034724)2.57999086
98DNA replication-independent nucleosome assembly (GO:0006336)2.57999086
99telomere maintenance via telomere lengthening (GO:0010833)2.57812608
100mRNA cleavage (GO:0006379)2.57017379

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.07965213
2GABP_17652178_ChIP-ChIP_JURKAT_Human3.97787491
3EST1_17652178_ChIP-ChIP_JURKAT_Human3.46570902
4E2F7_22180533_ChIP-Seq_HELA_Human3.41804821
5E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.19597895
6E2F4_17652178_ChIP-ChIP_JURKAT_Human3.14104947
7HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.80515725
8HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.75610628
9SALL1_21062744_ChIP-ChIP_HESCs_Human2.73065827
10ZNF274_21170338_ChIP-Seq_K562_Hela2.67477577
11ELK1_19687146_ChIP-ChIP_HELA_Human2.66756389
12EWS_26573619_Chip-Seq_HEK293_Human2.66494163
13VDR_22108803_ChIP-Seq_LS180_Human2.54211931
14FUS_26573619_Chip-Seq_HEK293_Human2.47156633
15TAF15_26573619_Chip-Seq_HEK293_Human2.40018521
16MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.32738878
17VDR_23849224_ChIP-Seq_CD4+_Human2.22486142
18ETS1_20019798_ChIP-Seq_JURKAT_Human2.14225416
19POU3F2_20337985_ChIP-ChIP_501MEL_Human2.12751617
20FLI1_27457419_Chip-Seq_LIVER_Mouse2.11908173
21ZFP57_27257070_Chip-Seq_ESCs_Mouse2.08287483
22GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.06347518
23CREB1_15753290_ChIP-ChIP_HEK293T_Human2.01880967
24JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.00995444
25CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.97249344
26PADI4_21655091_ChIP-ChIP_MCF-7_Human1.93099361
27FOXP3_21729870_ChIP-Seq_TREG_Human1.83711829
28CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.82341443
29ELF1_17652178_ChIP-ChIP_JURKAT_Human1.81563296
30P300_19829295_ChIP-Seq_ESCs_Human1.76676469
31MYC_18555785_ChIP-Seq_MESCs_Mouse1.74066323
32CTBP1_25329375_ChIP-Seq_LNCAP_Human1.73943923
33PCGF2_27294783_Chip-Seq_ESCs_Mouse1.70177057
34CTBP2_25329375_ChIP-Seq_LNCAP_Human1.68589312
35GBX2_23144817_ChIP-Seq_PC3_Human1.66400697
36NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.65032731
37POU5F1_16153702_ChIP-ChIP_HESCs_Human1.62979089
38PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.60867477
39NOTCH1_21737748_ChIP-Seq_TLL_Human1.54957676
40FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.53369622
41MYC_18940864_ChIP-ChIP_HL60_Human1.52985523
42KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.50620883
43PCGF2_27294783_Chip-Seq_NPCs_Mouse1.48361515
44ER_23166858_ChIP-Seq_MCF-7_Human1.47100857
45RBPJ_22232070_ChIP-Seq_NCS_Mouse1.44621288
46CBP_20019798_ChIP-Seq_JUKART_Human1.44581357
47IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.44581357
48FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.43311185
49AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.29889961
50SUZ12_27294783_Chip-Seq_NPCs_Mouse1.29499784
51SRF_21415370_ChIP-Seq_HL-1_Mouse1.24878507
52GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.22860656
53UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.21225492
54MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.21113486
55NFE2_27457419_Chip-Seq_LIVER_Mouse1.20127035
56EZH2_27294783_Chip-Seq_NPCs_Mouse1.18785149
57EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.17989559
58ELK1_22589737_ChIP-Seq_MCF10A_Human1.17708167
59DCP1A_22483619_ChIP-Seq_HELA_Human1.17575171
60YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.16300458
61TCF4_22108803_ChIP-Seq_LS180_Human1.15337719
62MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.15019818
63FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.14916292
64TTF2_22483619_ChIP-Seq_HELA_Human1.14899841
65E2F1_21310950_ChIP-Seq_MCF-7_Human1.14889045
66MYC_19030024_ChIP-ChIP_MESCs_Mouse1.14163795
67KLF5_20875108_ChIP-Seq_MESCs_Mouse1.13392213
68TOP2B_26459242_ChIP-Seq_MCF-7_Human1.11532887
69POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.10615945
70TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10615945
71AUTS2_25519132_ChIP-Seq_293T-REX_Human1.07737192
72MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.07692292
73GABP_19822575_ChIP-Seq_HepG2_Human1.07649486
74FOXM1_23109430_ChIP-Seq_U2OS_Human1.06139269
75SOX2_19829295_ChIP-Seq_ESCs_Human1.05095479
76NANOG_19829295_ChIP-Seq_ESCs_Human1.05095479
77TP53_22573176_ChIP-Seq_HFKS_Human1.04482862
78EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.04281473
79SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.02190266
80BCAT_22108803_ChIP-Seq_LS180_Human1.00955780
81NANOG_18555785_Chip-Seq_ESCs_Mouse1.00785264
82ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.00387632
83IRF1_19129219_ChIP-ChIP_H3396_Human0.99205994
84IGF1R_20145208_ChIP-Seq_DFB_Human0.98965816
85NANOG_16153702_ChIP-ChIP_HESCs_Human0.98508220
86TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.97592082
87P53_22387025_ChIP-Seq_ESCs_Mouse0.97384702
88FOXA1_25329375_ChIP-Seq_VCAP_Human0.96859137
89FOXA1_27270436_Chip-Seq_PROSTATE_Human0.96859137
90PIAS1_25552417_ChIP-Seq_VCAP_Human0.95665256
91SMAD4_21799915_ChIP-Seq_A2780_Human0.94804281
92HOXB4_20404135_ChIP-ChIP_EML_Mouse0.92966962
93SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.92661812
94E2F1_18555785_Chip-Seq_ESCs_Mouse0.91616529
95P300_18555785_Chip-Seq_ESCs_Mouse0.91535640
96POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.90085903
97TP63_19390658_ChIP-ChIP_HaCaT_Human0.89820327
98GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.89529040
99STAT3_23295773_ChIP-Seq_U87_Human0.89173532
100SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.88277884

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002822_catalepsy4.67296273
2MP0006292_abnormal_olfactory_placode3.60359809
3MP0008058_abnormal_DNA_repair3.59263470
4MP0008057_abnormal_DNA_replication3.57326703
5MP0000372_irregular_coat_pigmentation3.29662209
6MP0008877_abnormal_DNA_methylation2.90335811
7MP0010094_abnormal_chromosome_stability2.81074724
8MP0006072_abnormal_retinal_apoptosis2.33221004
9MP0001293_anophthalmia2.27847097
10MP0002102_abnormal_ear_morphology2.22539001
11MP0003136_yellow_coat_color2.22018626
12MP0003693_abnormal_embryo_hatching2.05861878
13MP0001529_abnormal_vocalization1.92645202
14MP0005646_abnormal_pituitary_gland1.88506399
15MP0001188_hyperpigmentation1.86205111
16MP0004957_abnormal_blastocyst_morpholog1.85429177
17MP0008995_early_reproductive_senescence1.83329496
18MP0002938_white_spotting1.81954103
19MP0003567_abnormal_fetal_cardiomyocyte1.75361246
20MP0009697_abnormal_copulation1.73321940
21MP0005551_abnormal_eye_electrophysiolog1.69996970
22MP0003890_abnormal_embryonic-extraembry1.69430030
23MP0005084_abnormal_gallbladder_morpholo1.68681284
24MP0003077_abnormal_cell_cycle1.68124025
25MP0003718_maternal_effect1.57611707
26MP0003111_abnormal_nucleus_morphology1.52211031
27MP0000631_abnormal_neuroendocrine_gland1.51883960
28MP0001984_abnormal_olfaction1.51293107
29MP0002234_abnormal_pharynx_morphology1.42178152
30MP0004142_abnormal_muscle_tone1.41544431
31MP0002837_dystrophic_cardiac_calcinosis1.40576771
32MP0002751_abnormal_autonomic_nervous1.40442824
33MP0002282_abnormal_trachea_morphology1.39501072
34MP0003786_premature_aging1.36825794
35MP0003195_calcinosis1.36704966
36MP0005174_abnormal_tail_pigmentation1.32569131
37MP0005253_abnormal_eye_physiology1.31296310
38MP0002160_abnormal_reproductive_system1.27699252
39MP0008872_abnormal_physiological_respon1.25111984
40MP0000569_abnormal_digit_pigmentation1.22917266
41MP0003806_abnormal_nucleotide_metabolis1.21374992
42MP0002090_abnormal_vision1.15041609
43MP0004145_abnormal_muscle_electrophysio1.14945092
44MP0001286_abnormal_eye_development1.14485349
45MP0003880_abnormal_central_pattern1.13441843
46MP0002233_abnormal_nose_morphology1.13172011
47MP0004133_heterotaxia1.13083565
48MP0001485_abnormal_pinna_reflex1.12805343
49MP0003937_abnormal_limbs/digits/tail_de1.11121398
50MP0000383_abnormal_hair_follicle1.10116013
51MP0008789_abnormal_olfactory_epithelium1.07925808
52MP0008932_abnormal_embryonic_tissue1.03394693
53MP0002210_abnormal_sex_determination1.01097171
54MP0002277_abnormal_respiratory_mucosa0.99005717
55MP0010386_abnormal_urinary_bladder0.98560472
56MP0003119_abnormal_digestive_system0.96748474
57MP0009046_muscle_twitch0.96516757
58MP0002736_abnormal_nociception_after0.95562767
59MP0004215_abnormal_myocardial_fiber0.94437272
60MP0000566_synostosis0.93601609
61MP0001929_abnormal_gametogenesis0.92055658
62MP0004147_increased_porphyrin_level0.91819657
63MP0000049_abnormal_middle_ear0.90913253
64MP0002928_abnormal_bile_duct0.90060373
65MP0005391_vision/eye_phenotype0.90035177
66MP0005075_abnormal_melanosome_morpholog0.89444741
67MP0002095_abnormal_skin_pigmentation0.88827286
68MP0006035_abnormal_mitochondrial_morpho0.87545581
69MP0005389_reproductive_system_phenotype0.83855407
70MP0006276_abnormal_autonomic_nervous0.83580872
71MP0000653_abnormal_sex_gland0.82847201
72MP0001346_abnormal_lacrimal_gland0.81920085
73MP0005408_hypopigmentation0.81368062
74MP0005394_taste/olfaction_phenotype0.81145196
75MP0005499_abnormal_olfactory_system0.81145196
76MP0000516_abnormal_urinary_system0.77820785
77MP0005367_renal/urinary_system_phenotyp0.77820785
78MP0001145_abnormal_male_reproductive0.77268320
79MP0002735_abnormal_chemical_nociception0.72311477
80MP0003283_abnormal_digestive_organ0.71572802
81MP0001119_abnormal_female_reproductive0.69800399
82MP0003787_abnormal_imprinting0.69258917
83MP0005195_abnormal_posterior_eye0.68669560
84MP0003646_muscle_fatigue0.67853664
85MP0002084_abnormal_developmental_patter0.67304511
86MP0001697_abnormal_embryo_size0.67015060
87MP0003121_genomic_imprinting0.66863831
88MP0003755_abnormal_palate_morphology0.66292112
89MP0003938_abnormal_ear_development0.65217164
90MP0009745_abnormal_behavioral_response0.64566845
91MP0002272_abnormal_nervous_system0.64135966
92MP0005085_abnormal_gallbladder_physiolo0.63967493
93MP0008007_abnormal_cellular_replicative0.63718516
94MP0010030_abnormal_orbit_morphology0.61565375
95MP0003186_abnormal_redox_activity0.60998840
96MP0003698_abnormal_male_reproductive0.60758528
97MP0001501_abnormal_sleep_pattern0.60645792
98MP0001764_abnormal_homeostasis0.60476525
99MP0001968_abnormal_touch/_nociception0.59968635
100MP0000647_abnormal_sebaceous_gland0.59565522

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the labia minora (HP:0012880)3.53338720
2Acute encephalopathy (HP:0006846)3.17113728
3Acute necrotizing encephalopathy (HP:0006965)3.14272867
4True hermaphroditism (HP:0010459)3.08255603
5Septo-optic dysplasia (HP:0100842)2.94883048
6Congenital, generalized hypertrichosis (HP:0004540)2.91447099
7Pancreatic cysts (HP:0001737)2.88586169
8Mitochondrial inheritance (HP:0001427)2.82717157
9Aplasia/Hypoplasia of the uvula (HP:0010293)2.82570670
10Chromosomal breakage induced by crosslinking agents (HP:0003221)2.80242762
11Progressive macrocephaly (HP:0004481)2.77122177
12Abnormal mitochondria in muscle tissue (HP:0008316)2.75555181
13Increased CSF lactate (HP:0002490)2.73549809
14Methylmalonic acidemia (HP:0002912)2.71899709
15Meckel diverticulum (HP:0002245)2.71772694
16Increased hepatocellular lipid droplets (HP:0006565)2.70207714
17Hepatocellular necrosis (HP:0001404)2.69431027
18Pancreatic fibrosis (HP:0100732)2.69087246
19Lipid accumulation in hepatocytes (HP:0006561)2.66386744
20Abnormality of the ileum (HP:0001549)2.66122480
21Gaze-evoked nystagmus (HP:0000640)2.65525508
22Abnormality of chromosome stability (HP:0003220)2.59499698
23Chromsome breakage (HP:0040012)2.53767813
24Hepatic necrosis (HP:0002605)2.45943866
25Decreased activity of mitochondrial respiratory chain (HP:0008972)2.45182447
26Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.45182447
27Progressive inability to walk (HP:0002505)2.43519757
28Abnormality of the preputium (HP:0100587)2.40893403
29Abnormality of midbrain morphology (HP:0002418)2.40748734
30Molar tooth sign on MRI (HP:0002419)2.40748734
31Abolished electroretinogram (ERG) (HP:0000550)2.38816931
32Renal cortical cysts (HP:0000803)2.38680499
33Hyperglycinemia (HP:0002154)2.36694203
34Ependymoma (HP:0002888)2.35486405
35Volvulus (HP:0002580)2.32734569
36Inability to walk (HP:0002540)2.25958210
37Attenuation of retinal blood vessels (HP:0007843)2.25859563
38Sensory axonal neuropathy (HP:0003390)2.23919859
39Degeneration of anterior horn cells (HP:0002398)2.19830553
40Abnormality of the anterior horn cell (HP:0006802)2.19830553
41Medial flaring of the eyebrow (HP:0010747)2.17969471
42Hyperglycinuria (HP:0003108)2.16978072
43Nephronophthisis (HP:0000090)2.16423107
44Chronic hepatic failure (HP:0100626)2.15473978
45Cerebral edema (HP:0002181)2.15366618
46Clubbing of toes (HP:0100760)2.15258382
47Optic nerve hypoplasia (HP:0000609)2.11738783
48Congenital stationary night blindness (HP:0007642)2.11538884
49Optic disc pallor (HP:0000543)2.09794866
503-Methylglutaconic aciduria (HP:0003535)2.09291458
51Abnormality of the renal cortex (HP:0011035)2.03374399
52Increased serum lactate (HP:0002151)2.03338219
53Methylmalonic aciduria (HP:0012120)2.01117585
54Glioma (HP:0009733)1.99553899
55Hypoplasia of the pons (HP:0012110)1.98740301
56Hypothermia (HP:0002045)1.97095632
57Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.96827241
58Duodenal stenosis (HP:0100867)1.94691995
59Small intestinal stenosis (HP:0012848)1.94691995
60Sloping forehead (HP:0000340)1.93623603
61Pancytopenia (HP:0001876)1.88640807
62Triphalangeal thumb (HP:0001199)1.88163144
63Aplasia/Hypoplasia of the tongue (HP:0010295)1.86091159
64Abnormality of aspartate family amino acid metabolism (HP:0010899)1.85770203
65Decreased central vision (HP:0007663)1.85539489
66Abnormality of serum amino acid levels (HP:0003112)1.84247874
67Gonadotropin excess (HP:0000837)1.83938128
68Abnormality of the pons (HP:0007361)1.82780391
69Lactic acidosis (HP:0003128)1.82117480
70Colon cancer (HP:0003003)1.81694020
71Central scotoma (HP:0000603)1.81483059
72Thyroiditis (HP:0100646)1.80963729
73Leukodystrophy (HP:0002415)1.80927293
74Abnormality of the duodenum (HP:0002246)1.80672018
75Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.80204602
76Atonic seizures (HP:0010819)1.77398660
77Aplastic anemia (HP:0001915)1.76889759
78Abnormality of the renal medulla (HP:0100957)1.76084770
79Abnormality of serine family amino acid metabolism (HP:0010894)1.73216700
80Abnormality of glycine metabolism (HP:0010895)1.73216700
81Constricted visual fields (HP:0001133)1.71574296
82Congenital primary aphakia (HP:0007707)1.70405383
83Broad-based gait (HP:0002136)1.70197885
84Male pseudohermaphroditism (HP:0000037)1.70176482
85Astigmatism (HP:0000483)1.66422078
86Hypoproteinemia (HP:0003075)1.65363201
87Renal Fanconi syndrome (HP:0001994)1.65122027
88Nephrogenic diabetes insipidus (HP:0009806)1.64512704
89Pendular nystagmus (HP:0012043)1.64095162
90Decreased electroretinogram (ERG) amplitude (HP:0000654)1.64074249
91Neoplasm of the adrenal cortex (HP:0100641)1.63955840
92Abnormal rod and cone electroretinograms (HP:0008323)1.63746833
93Birth length less than 3rd percentile (HP:0003561)1.63488759
94Growth hormone deficiency (HP:0000824)1.62233830
95Respiratory failure (HP:0002878)1.61233614
96Shoulder girdle muscle weakness (HP:0003547)1.61074359
97Type II lissencephaly (HP:0007260)1.60930397
98Absent radius (HP:0003974)1.59711479
99Astrocytoma (HP:0009592)1.59168085
100Abnormality of the astrocytes (HP:0100707)1.59168085

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ZAK3.19768897
2EIF2AK33.14473128
3TSSK63.13025988
4MST42.72262164
5FRK2.64078205
6MAP4K22.59562068
7VRK22.43272150
8PBK2.41195447
9WNK32.38849505
10TRIM282.33457740
11BMPR1B2.28767091
12MKNK12.26899262
13EIF2AK12.25054637
14BUB12.13142045
15SRPK12.05970856
16PLK32.03164493
17CDK191.98528350
18AKT31.93353029
19MKNK21.93125568
20VRK11.91057167
21CDC71.90831044
22PLK41.90078669
23BRSK21.71143253
24PNCK1.63348585
25DYRK31.56135126
26TNIK1.55070263
27OXSR11.45761322
28NEK11.36735328
29NUAK11.35346397
30NME11.33709602
31TNK21.31226536
32WEE11.31121536
33PINK11.29415565
34WNK41.28393912
35STK391.26977336
36ADRBK21.24780678
37GRK11.23344439
38TAF11.17279568
39TTK1.14234540
40PLK21.13094574
41PLK11.12171300
42ATR1.10913950
43TGFBR11.09412164
44TLK11.08152663
45STK38L1.01956935
46PASK0.98212434
47BRD40.97882274
48MAPKAPK30.97860834
49CHEK20.91144129
50STK160.90061273
51ACVR1B0.89394694
52INSRR0.88158957
53RPS6KA40.84321424
54ERBB30.82454368
55CDK80.82434319
56BCKDK0.79354457
57CSNK1G10.75175484
58EIF2AK20.73741042
59NEK20.71441033
60AURKB0.65364120
61CDK30.64765752
62FGFR10.64115912
63FLT30.62529751
64ATM0.59361511
65CCNB10.58594829
66MYLK0.57863371
67TXK0.57259586
68BRSK10.56679153
69DAPK10.56449924
70TAOK30.55961543
71MAP3K40.49210613
72MAP3K120.48256282
73CSNK1E0.48215095
74DYRK20.47542422
75CHEK10.47187945
76CSNK2A10.45529107
77MAPK150.44621093
78KIT0.44291446
79CSNK1G30.43691839
80TEC0.43151751
81CSNK2A20.42884579
82CSNK1A10.42618444
83MAP3K100.39545969
84PRKCG0.39306867
85PRKCE0.39192109
86WNK10.38339619
87PAK30.37317994
88MAP2K70.36994180
89MAPK130.36113001
90NLK0.35716272
91RPS6KA50.34483555
92CSNK1A1L0.34412639
93FGFR20.32585764
94CDK90.31490228
95OBSCN0.25823471
96CASK0.25763901
97CSNK1G20.25222627
98PRKACB0.25041760
99STK30.24700633
100MINK10.21708224

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030503.99804453
2Non-homologous end-joining_Homo sapiens_hsa034503.35143861
3Homologous recombination_Homo sapiens_hsa034403.01259255
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.98051938
5Protein export_Homo sapiens_hsa030602.89165191
6Mismatch repair_Homo sapiens_hsa034302.74249160
7DNA replication_Homo sapiens_hsa030302.72867692
8Basal transcription factors_Homo sapiens_hsa030222.72844186
9RNA polymerase_Homo sapiens_hsa030202.68924841
10Oxidative phosphorylation_Homo sapiens_hsa001902.54154996
11Fanconi anemia pathway_Homo sapiens_hsa034602.38230201
12Propanoate metabolism_Homo sapiens_hsa006402.31881371
13One carbon pool by folate_Homo sapiens_hsa006702.28282947
14RNA degradation_Homo sapiens_hsa030182.17675176
15Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.15368380
16Spliceosome_Homo sapiens_hsa030402.09430683
17Ribosome_Homo sapiens_hsa030102.02819784
18Parkinsons disease_Homo sapiens_hsa050122.02732530
19RNA transport_Homo sapiens_hsa030131.93333261
20Nucleotide excision repair_Homo sapiens_hsa034201.91170425
21Base excision repair_Homo sapiens_hsa034101.81870696
22Huntingtons disease_Homo sapiens_hsa050161.57097552
23Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.55047937
24Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.53965567
25Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.52733992
26Phototransduction_Homo sapiens_hsa047441.52460076
27Pyrimidine metabolism_Homo sapiens_hsa002401.40113172
28Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.39899656
29Asthma_Homo sapiens_hsa053101.36223475
30Purine metabolism_Homo sapiens_hsa002301.35789015
31Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.32209780
32Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.30932587
33Alzheimers disease_Homo sapiens_hsa050101.29697472
34Selenocompound metabolism_Homo sapiens_hsa004501.28118749
35Cysteine and methionine metabolism_Homo sapiens_hsa002701.25522307
36Butanoate metabolism_Homo sapiens_hsa006501.14859559
37Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.08041587
38Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.05089156
39mRNA surveillance pathway_Homo sapiens_hsa030150.98814088
40Intestinal immune network for IgA production_Homo sapiens_hsa046720.96689540
41Taste transduction_Homo sapiens_hsa047420.96540383
42Cell cycle_Homo sapiens_hsa041100.93940314
43Allograft rejection_Homo sapiens_hsa053300.93264279
44Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.92149113
45Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.92083359
46p53 signaling pathway_Homo sapiens_hsa041150.90601283
47Regulation of autophagy_Homo sapiens_hsa041400.89591875
48Nicotine addiction_Homo sapiens_hsa050330.85902484
49Olfactory transduction_Homo sapiens_hsa047400.82564257
50Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.79246977
51Linoleic acid metabolism_Homo sapiens_hsa005910.78092498
52Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.78070390
53Tryptophan metabolism_Homo sapiens_hsa003800.77326764
54Vitamin B6 metabolism_Homo sapiens_hsa007500.75526333
55Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.75347923
56Autoimmune thyroid disease_Homo sapiens_hsa053200.73813888
57Steroid biosynthesis_Homo sapiens_hsa001000.73206673
58Caffeine metabolism_Homo sapiens_hsa002320.71942295
59Type I diabetes mellitus_Homo sapiens_hsa049400.68522431
60Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.63244514
61Peroxisome_Homo sapiens_hsa041460.58654978
62Metabolic pathways_Homo sapiens_hsa011000.55205299
63Primary immunodeficiency_Homo sapiens_hsa053400.54854998
64Steroid hormone biosynthesis_Homo sapiens_hsa001400.53955998
65Pyruvate metabolism_Homo sapiens_hsa006200.52936149
66Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.51861168
67TGF-beta signaling pathway_Homo sapiens_hsa043500.51468425
68Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.51139614
69Chemical carcinogenesis_Homo sapiens_hsa052040.50972045
70Oocyte meiosis_Homo sapiens_hsa041140.50833864
71Glutathione metabolism_Homo sapiens_hsa004800.49437268
72alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.48809437
73Cardiac muscle contraction_Homo sapiens_hsa042600.45766131
74Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.45559354
75Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.42591033
76Vitamin digestion and absorption_Homo sapiens_hsa049770.40670065
77Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.38171296
78Graft-versus-host disease_Homo sapiens_hsa053320.37048932
79Hedgehog signaling pathway_Homo sapiens_hsa043400.35675387
80Maturity onset diabetes of the young_Homo sapiens_hsa049500.35634836
81Epstein-Barr virus infection_Homo sapiens_hsa051690.33990563
82Antigen processing and presentation_Homo sapiens_hsa046120.33955556
83beta-Alanine metabolism_Homo sapiens_hsa004100.33946999
84Lysine degradation_Homo sapiens_hsa003100.32685082
85Fat digestion and absorption_Homo sapiens_hsa049750.32130274
86Ether lipid metabolism_Homo sapiens_hsa005650.31185607
87Pentose and glucuronate interconversions_Homo sapiens_hsa000400.30997384
88Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.30545907
89Systemic lupus erythematosus_Homo sapiens_hsa053220.30036255
90Drug metabolism - other enzymes_Homo sapiens_hsa009830.28730735
91Retinol metabolism_Homo sapiens_hsa008300.28394981
92Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.25349795
93Nitrogen metabolism_Homo sapiens_hsa009100.24769071
94Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.24576346
95Fatty acid degradation_Homo sapiens_hsa000710.23995791
96ABC transporters_Homo sapiens_hsa020100.23482552
97Rheumatoid arthritis_Homo sapiens_hsa053230.21494393
98Dorso-ventral axis formation_Homo sapiens_hsa043200.20774113
99Hematopoietic cell lineage_Homo sapiens_hsa046400.20066387
100Wnt signaling pathway_Homo sapiens_hsa043100.18796888

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »