HNRNPA1P15

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)5.20628172
2regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450915.06536812
3cytidine catabolic process (GO:0006216)4.52255704
4cytidine deamination (GO:0009972)4.52255704
5cytidine metabolic process (GO:0046087)4.52255704
6rRNA modification (GO:0000154)4.42283802
7response to pheromone (GO:0019236)4.34576289
8rRNA methylation (GO:0031167)4.13294552
9mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.11841776
10sperm motility (GO:0030317)4.04890806
11fusion of sperm to egg plasma membrane (GO:0007342)4.02535010
12acrosome reaction (GO:0007340)3.88451962
13pyrimidine ribonucleoside catabolic process (GO:0046133)3.79412773
14cell wall macromolecule metabolic process (GO:0044036)3.72203844
15energy coupled proton transport, down electrochemical gradient (GO:0015985)3.69653264
16ATP synthesis coupled proton transport (GO:0015986)3.69653264
17proteasome assembly (GO:0043248)3.53118300
18cell wall macromolecule catabolic process (GO:0016998)3.46175919
19negative regulation of calcium ion transport into cytosol (GO:0010523)3.41286454
20mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.38694306
21transcription from mitochondrial promoter (GO:0006390)3.35854322
22negative regulation of heart rate (GO:0010459)3.34348385
23nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.31526732
24exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.29278269
25Arp2/3 complex-mediated actin nucleation (GO:0034314)3.22584932
26protein neddylation (GO:0045116)3.21746240
27positive regulation of interleukin-17 production (GO:0032740)3.19030755
28mannosylation (GO:0097502)3.17970525
29positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)3.16523138
30antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.13002239
31mast cell activation (GO:0045576)3.11124402
32regulation of cellular amino acid metabolic process (GO:0006521)3.10736364
33purine nucleotide salvage (GO:0032261)3.10193255
34regulation of B cell receptor signaling pathway (GO:0050855)3.07139748
35actin nucleation (GO:0045010)3.04137617
36plasma membrane fusion (GO:0045026)3.03588530
37mast cell degranulation (GO:0043303)3.02348731
38mast cell activation involved in immune response (GO:0002279)3.02348731
39regulation of regulatory T cell differentiation (GO:0045589)3.02126401
40RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.00655619
41positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.96844560
42positive regulation of alpha-beta T cell proliferation (GO:0046641)2.96235858
43multicellular organism reproduction (GO:0032504)2.95761932
44DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.95020655
45negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.94205317
46signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.92836103
47signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.92836103
48signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.92836103
49organic cation transport (GO:0015695)2.92471712
50DNA double-strand break processing (GO:0000729)2.92307274
51signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.87954967
52intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.87954967
53cellular response to interleukin-15 (GO:0071350)2.87844262
54respiratory electron transport chain (GO:0022904)2.85591721
55regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)2.85479386
56spermatid nucleus differentiation (GO:0007289)2.83311656
57cellular ketone body metabolic process (GO:0046950)2.82644837
58electron transport chain (GO:0022900)2.82635990
59positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.81177607
60positive regulation of T cell mediated cytotoxicity (GO:0001916)2.77987661
61positive thymic T cell selection (GO:0045059)2.76410191
62positive regulation of defense response to virus by host (GO:0002230)2.74382303
63centriole replication (GO:0007099)2.74007120
64signal transduction involved in DNA damage checkpoint (GO:0072422)2.73577028
65signal transduction involved in DNA integrity checkpoint (GO:0072401)2.73577028
66signal transduction involved in cell cycle checkpoint (GO:0072395)2.71186182
67epithelial cilium movement (GO:0003351)2.69977966
68regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)2.68610611
69regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.68266972
70deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.67035705
71negative T cell selection (GO:0043383)2.66080985
72positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)2.65933016
73platelet dense granule organization (GO:0060155)2.65385361
74GPI anchor metabolic process (GO:0006505)2.60732522
75regulation of alpha-beta T cell proliferation (GO:0046640)2.60683235
76antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.60483319
77protein polyglutamylation (GO:0018095)2.59770012
78positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.59375568
79negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.58760334
80negative regulation of ligase activity (GO:0051352)2.58418339
81negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.58418339
82regulation of T cell receptor signaling pathway (GO:0050856)2.57909315
83spermatid development (GO:0007286)2.55631596
84oxidative phosphorylation (GO:0006119)2.55488670
85ribosome assembly (GO:0042255)2.53465927
86GPI anchor biosynthetic process (GO:0006506)2.51847027
87regulation of T cell mediated cytotoxicity (GO:0001914)2.51822065
88purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)2.51618618
89antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.51595264
90axonemal dynein complex assembly (GO:0070286)2.51341815
91positive T cell selection (GO:0043368)2.50920229
92L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.50633157
93negative regulation of T cell apoptotic process (GO:0070233)2.50390015
94positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.49613737
95ketone body metabolic process (GO:1902224)2.49586493
96regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.48796733
97regulation of interleukin-8 secretion (GO:2000482)2.47768693
98positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.46441427
99sperm-egg recognition (GO:0035036)2.45912319
100respiratory chain complex IV assembly (GO:0008535)2.45552930

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human3.22168784
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.98998137
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.91600213
4GABP_17652178_ChIP-ChIP_JURKAT_Human2.64904136
5IGF1R_20145208_ChIP-Seq_DFB_Human2.59598030
6VDR_22108803_ChIP-Seq_LS180_Human2.56838003
7NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.55562364
8IRF8_22096565_ChIP-ChIP_GC-B_Human2.40180533
9RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.35923030
10FLI1_27457419_Chip-Seq_LIVER_Mouse2.35026295
11ZNF274_21170338_ChIP-Seq_K562_Hela2.32458471
12TAF15_26573619_Chip-Seq_HEK293_Human2.28621259
13HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.24483931
14EST1_17652178_ChIP-ChIP_JURKAT_Human2.23508257
15MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.14002850
16VDR_23849224_ChIP-Seq_CD4+_Human2.08238047
17IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.05067936
18E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.04594146
19FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.02774804
20CTBP2_25329375_ChIP-Seq_LNCAP_Human2.00345649
21P300_19829295_ChIP-Seq_ESCs_Human1.96539631
22EWS_26573619_Chip-Seq_HEK293_Human1.94921893
23POU3F2_20337985_ChIP-ChIP_501MEL_Human1.94889560
24HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.94450902
25PCGF2_27294783_Chip-Seq_ESCs_Mouse1.88150356
26ER_23166858_ChIP-Seq_MCF-7_Human1.87499641
27ELF1_17652178_ChIP-ChIP_JURKAT_Human1.84419743
28IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.82237129
29CBP_20019798_ChIP-Seq_JUKART_Human1.72744285
30IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.72744285
31FOXA1_27270436_Chip-Seq_PROSTATE_Human1.70841392
32FOXA1_25329375_ChIP-Seq_VCAP_Human1.70841392
33ERG_20517297_ChIP-Seq_VCAP_Human1.70387174
34FUS_26573619_Chip-Seq_HEK293_Human1.69792074
35EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.66269673
36CTBP1_25329375_ChIP-Seq_LNCAP_Human1.65192676
37SOX2_19829295_ChIP-Seq_ESCs_Human1.62081423
38NANOG_19829295_ChIP-Seq_ESCs_Human1.62081423
39FOXP3_21729870_ChIP-Seq_TREG_Human1.60415060
40IRF8_21731497_ChIP-ChIP_J774_Mouse1.58381156
41MYB_26560356_Chip-Seq_TH2_Human1.54910601
42GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.54261362
43FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.53932457
44JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.52311584
45TP53_22573176_ChIP-Seq_HFKS_Human1.51703581
46GATA3_26560356_Chip-Seq_TH2_Human1.47178914
47CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.46751310
48PCGF2_27294783_Chip-Seq_NPCs_Mouse1.45295046
49GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.42798014
50AUTS2_25519132_ChIP-Seq_293T-REX_Human1.42055226
51MYC_18940864_ChIP-ChIP_HL60_Human1.39608961
52ELK1_19687146_ChIP-ChIP_HELA_Human1.38437730
53UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.37196754
54FOXA1_21572438_ChIP-Seq_LNCaP_Human1.33052430
55EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.32882057
56GATA3_21878914_ChIP-Seq_MCF-7_Human1.31263616
57RUNX_20019798_ChIP-Seq_JUKART_Human1.30663757
58WDR5_24793694_ChIP-Seq_LNCAP_Human1.30363582
59SUZ12_27294783_Chip-Seq_NPCs_Mouse1.29211475
60CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.26461386
61STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.25995302
62ETS1_20019798_ChIP-Seq_JURKAT_Human1.25532580
63GATA3_27048872_Chip-Seq_THYMUS_Human1.24455649
64AR_20517297_ChIP-Seq_VCAP_Human1.23873818
65NFE2_27457419_Chip-Seq_LIVER_Mouse1.23532391
66ZFP57_27257070_Chip-Seq_ESCs_Mouse1.23281691
67NANOG_20526341_ChIP-Seq_ESCs_Human1.19989116
68LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.18343586
69E2F4_17652178_ChIP-ChIP_JURKAT_Human1.18212002
70E2F7_22180533_ChIP-Seq_HELA_Human1.18117938
71NCOR_22424771_ChIP-Seq_293T_Human1.17829265
72KLF5_20875108_ChIP-Seq_MESCs_Mouse1.17014171
73ETV2_25802403_ChIP-Seq_MESCs_Mouse1.16524566
74TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14253191
75POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.14253191
76MYC_19829295_ChIP-Seq_ESCs_Human1.13345141
77AR_25329375_ChIP-Seq_VCAP_Human1.11228349
78PRDM14_20953172_ChIP-Seq_ESCs_Human1.10791851
79SRF_21415370_ChIP-Seq_HL-1_Mouse1.08649752
80MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.08503516
81CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.08380765
82CREB1_15753290_ChIP-ChIP_HEK293T_Human1.07743568
83TAF2_19829295_ChIP-Seq_ESCs_Human1.07329839
84EZH2_27294783_Chip-Seq_NPCs_Mouse1.06910670
85HOXB7_26014856_ChIP-Seq_BT474_Human1.03666694
86TCF4_22108803_ChIP-Seq_LS180_Human1.02903399
87PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.02490606
88SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.02213738
89PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.02122811
90RBPJ_21746931_ChIP-Seq_IB4_Human1.01736814
91EGR1_23403033_ChIP-Seq_LIVER_Mouse1.01363575
92HTT_18923047_ChIP-ChIP_STHdh_Human1.01156232
93TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.00177673
94CEBPB_22108803_ChIP-Seq_LS180_Human0.99228668
95GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.97904035
96PHF8_20622853_ChIP-Seq_HELA_Human0.97835308
97RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.97760601
98TOP2B_26459242_ChIP-Seq_MCF-7_Human0.97594457
99BCAT_22108803_ChIP-Seq_LS180_Human0.97498283
100GATA3_26560356_Chip-Seq_TH1_Human0.97012162

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005671_abnormal_response_to4.13458682
2MP0005410_abnormal_fertilization3.56316769
3MP0001835_abnormal_antigen_presentation3.51232437
4MP0005084_abnormal_gallbladder_morpholo2.83393184
5MP0009697_abnormal_copulation2.80452303
6MP0005645_abnormal_hypothalamus_physiol2.78365306
7MP0006292_abnormal_olfactory_placode2.65641669
8MP0006072_abnormal_retinal_apoptosis2.29660106
9MP0005451_abnormal_body_composition2.27850068
10MP0009785_altered_susceptibility_to2.27112648
11MP0003806_abnormal_nucleotide_metabolis2.21427775
12MP0002148_abnormal_hypersensitivity_rea1.97443524
13MP0005377_hearing/vestibular/ear_phenot1.93626548
14MP0003878_abnormal_ear_physiology1.93626548
15MP0001800_abnormal_humoral_immune1.84993745
16MP0008877_abnormal_DNA_methylation1.81354779
17MP0004147_increased_porphyrin_level1.80839214
18MP0005000_abnormal_immune_tolerance1.69094927
19MP0001790_abnormal_immune_system1.66449421
20MP0005387_immune_system_phenotype1.66449421
21MP0003646_muscle_fatigue1.65191075
22MP0003011_delayed_dark_adaptation1.64602181
23MP0003763_abnormal_thymus_physiology1.64158126
24MP0003718_maternal_effect1.61539842
25MP0000685_abnormal_immune_system1.60305492
26MP0009333_abnormal_splenocyte_physiolog1.58153429
27MP0003786_premature_aging1.57744490
28MP0002138_abnormal_hepatobiliary_system1.57382629
29MP0008995_early_reproductive_senescence1.55943325
30MP0005253_abnormal_eye_physiology1.54939423
31MP0005075_abnormal_melanosome_morpholog1.48992012
32MP0005646_abnormal_pituitary_gland1.47414529
33MP0001929_abnormal_gametogenesis1.45646757
34MP0005551_abnormal_eye_electrophysiolog1.44383623
35MP0008872_abnormal_physiological_respon1.43968822
36MP0002723_abnormal_immune_serum1.43755499
37MP0005083_abnormal_biliary_tract1.41949257
38MP0001873_stomach_inflammation1.37891334
39MP0003698_abnormal_male_reproductive1.35143954
40MP0002102_abnormal_ear_morphology1.34898613
41MP0002876_abnormal_thyroid_physiology1.30729873
42MP0002452_abnormal_antigen_presenting1.30013119
43MP0002420_abnormal_adaptive_immunity1.29908184
44MP0002234_abnormal_pharynx_morphology1.27260424
45MP0006036_abnormal_mitochondrial_physio1.26820584
46MP0001819_abnormal_immune_cell1.25546196
47MP0001853_heart_inflammation1.22977836
48MP0009764_decreased_sensitivity_to1.21561590
49MP0002166_altered_tumor_susceptibility1.21106780
50MP0005379_endocrine/exocrine_gland_phen1.19514446
51MP0005025_abnormal_response_to1.17765830
52MP0001905_abnormal_dopamine_level1.15941626
53MP0001764_abnormal_homeostasis1.15922043
54MP0002282_abnormal_trachea_morphology1.15525935
55MP0008875_abnormal_xenobiotic_pharmacok1.13522766
56MP0001968_abnormal_touch/_nociception1.13329158
57MP0002398_abnormal_bone_marrow1.12141960
58MP0003252_abnormal_bile_duct1.11105936
59MP0003195_calcinosis1.10738361
60MP0001485_abnormal_pinna_reflex1.06482627
61MP0000716_abnormal_immune_system1.06356328
62MP0002006_tumorigenesis1.04646652
63MP0005085_abnormal_gallbladder_physiolo1.04238419
64MP0002132_abnormal_respiratory_system1.04209892
65MP0000372_irregular_coat_pigmentation1.03894586
66MP0001529_abnormal_vocalization1.03715850
67MP0010094_abnormal_chromosome_stability0.96798267
68MP0005365_abnormal_bile_salt0.96574538
69MP0000689_abnormal_spleen_morphology0.95276590
70MP0000703_abnormal_thymus_morphology0.90963183
71MP0002210_abnormal_sex_determination0.90904601
72MP0002722_abnormal_immune_system0.90712130
73MP0002736_abnormal_nociception_after0.88025716
74MP0002277_abnormal_respiratory_mucosa0.86881841
75MP0004142_abnormal_muscle_tone0.85458679
76MP0008789_abnormal_olfactory_epithelium0.84383145
77MP0003724_increased_susceptibility_to0.82838350
78MP0006082_CNS_inflammation0.82188107
79MP0003866_abnormal_defecation0.82115879
80MP0010386_abnormal_urinary_bladder0.80785890
81MP0002429_abnormal_blood_cell0.77133157
82MP0001845_abnormal_inflammatory_respons0.77099498
83MP0000230_abnormal_systemic_arterial0.76720048
84MP0010155_abnormal_intestine_physiology0.76393328
85MP0001145_abnormal_male_reproductive0.76374918
86MP0002160_abnormal_reproductive_system0.75831560
87MP0001986_abnormal_taste_sensitivity0.75829944
88MP0005389_reproductive_system_phenotype0.75188361
89MP0002405_respiratory_system_inflammati0.74725758
90MP0005332_abnormal_amino_acid0.74247663
91MP0000653_abnormal_sex_gland0.73804327
92MP0005408_hypopigmentation0.72850101
93MP0006276_abnormal_autonomic_nervous0.72375488
94MP0002095_abnormal_skin_pigmentation0.72224630
95MP0002693_abnormal_pancreas_physiology0.69231158
96MP0008058_abnormal_DNA_repair0.69044956
97MP0000465_gastrointestinal_hemorrhage0.68706682
98MP0002272_abnormal_nervous_system0.68069221
99MP0002161_abnormal_fertility/fecundity0.66009621
100MP0001501_abnormal_sleep_pattern0.64171858

Predicted human phenotypes

RankGene SetZ-score
1B lymphocytopenia (HP:0010976)4.14688483
2Abnormality of B cell number (HP:0010975)4.02155029
3Congenital stationary night blindness (HP:0007642)3.78875384
4Elevated erythrocyte sedimentation rate (HP:0003565)3.74582214
5Abnormal rod and cone electroretinograms (HP:0008323)3.65710514
6IgG deficiency (HP:0004315)3.54409592
7Severe combined immunodeficiency (HP:0004430)3.51565136
8Absent rod-and cone-mediated responses on ERG (HP:0007688)3.50895350
9Hypoproteinemia (HP:0003075)3.44854918
10Thyroiditis (HP:0100646)3.23057865
11Nephronophthisis (HP:0000090)3.14301849
12Lipid accumulation in hepatocytes (HP:0006561)3.14005407
133-Methylglutaconic aciduria (HP:0003535)3.12450498
14Abolished electroretinogram (ERG) (HP:0000550)3.09107321
15Chronic sinusitis (HP:0011109)3.08928844
16T lymphocytopenia (HP:0005403)3.07668129
17Increased hepatocellular lipid droplets (HP:0006565)3.03324465
18Stomatitis (HP:0010280)3.00035761
19Decreased central vision (HP:0007663)2.97064133
20Severe visual impairment (HP:0001141)2.96824228
21Abnormality of T cell number (HP:0011839)2.93700206
22Mitochondrial inheritance (HP:0001427)2.91328677
23Attenuation of retinal blood vessels (HP:0007843)2.89291563
24Congenital, generalized hypertrichosis (HP:0004540)2.77564320
25Combined immunodeficiency (HP:0005387)2.69658462
26Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.67105477
27Renal Fanconi syndrome (HP:0001994)2.66362877
28True hermaphroditism (HP:0010459)2.61194978
29Abnormality of the prostate (HP:0008775)2.60287908
30Increased IgM level (HP:0003496)2.56632202
31Increased CSF lactate (HP:0002490)2.56311471
32Increased intramyocellular lipid droplets (HP:0012240)2.55197578
33Hepatic necrosis (HP:0002605)2.52234833
34Methylmalonic acidemia (HP:0002912)2.51512762
35Hepatocellular necrosis (HP:0001404)2.48723150
36Acute necrotizing encephalopathy (HP:0006965)2.47218687
37Recurrent bronchitis (HP:0002837)2.44858668
38Pancreatic cysts (HP:0001737)2.44294408
39Abnormality of midbrain morphology (HP:0002418)2.43449489
40Molar tooth sign on MRI (HP:0002419)2.43449489
41Bony spicule pigmentary retinopathy (HP:0007737)2.41512046
42Exertional dyspnea (HP:0002875)2.37632281
43Dynein arm defect of respiratory motile cilia (HP:0012255)2.37220269
44Absent/shortened dynein arms (HP:0200106)2.37220269
45Aplastic anemia (HP:0001915)2.35088139
46Hypoplasia of the thymus (HP:0000778)2.33459258
47Increased muscle lipid content (HP:0009058)2.29223280
48Type I transferrin isoform profile (HP:0003642)2.27968800
49Optic disc pallor (HP:0000543)2.27474639
50Abnormality of the renal medulla (HP:0100957)2.26107469
51Autoimmune hemolytic anemia (HP:0001890)2.25650844
52Pancreatic fibrosis (HP:0100732)2.24987827
53Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.23540900
54Methylmalonic aciduria (HP:0012120)2.22455769
55Agammaglobulinemia (HP:0004432)2.18241857
56Abnormality of T cells (HP:0002843)2.16664855
57Central scotoma (HP:0000603)2.12612224
58Abnormal mitochondria in muscle tissue (HP:0008316)2.12391446
59Abnormality of macular pigmentation (HP:0008002)2.10925862
60Pendular nystagmus (HP:0012043)2.09222114
61Constricted visual fields (HP:0001133)2.08818190
62Abnormality of eosinophils (HP:0001879)2.06157923
63Progressive macrocephaly (HP:0004481)2.06011842
64Decreased electroretinogram (ERG) amplitude (HP:0000654)2.05689182
65Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.03436496
66Abnormality of alanine metabolism (HP:0010916)2.03436496
67Hyperalaninemia (HP:0003348)2.03436496
68Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.96603494
69Encephalitis (HP:0002383)1.96514328
70Bronchitis (HP:0012387)1.95294408
71Acute encephalopathy (HP:0006846)1.93766759
72Azoospermia (HP:0000027)1.93159237
73Pancytopenia (HP:0001876)1.93058575
74Increased serum lactate (HP:0002151)1.92179093
75Glycosuria (HP:0003076)1.91998626
76Abnormality of urine glucose concentration (HP:0011016)1.91998626
77Abnormal respiratory motile cilium physiology (HP:0012261)1.91116344
78Renal cortical cysts (HP:0000803)1.88415260
79Decreased activity of mitochondrial respiratory chain (HP:0008972)1.87495176
80Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.87495176
81Abnormal ciliary motility (HP:0012262)1.85081714
82Respiratory difficulties (HP:0002880)1.84650001
83Abnormal respiratory epithelium morphology (HP:0012253)1.84618502
84Abnormal respiratory motile cilium morphology (HP:0005938)1.84618502
85Cerebral edema (HP:0002181)1.84447982
86Abnormal spermatogenesis (HP:0008669)1.84029420
87Sensory axonal neuropathy (HP:0003390)1.83091120
88Hypothermia (HP:0002045)1.81869487
89Meningitis (HP:0001287)1.81744541
90Scotoma (HP:0000575)1.81613366
91Abnormality of dicarboxylic acid metabolism (HP:0010995)1.80118909
92Dicarboxylic aciduria (HP:0003215)1.80118909
93Eosinophilia (HP:0001880)1.75807774
94Abnormal protein glycosylation (HP:0012346)1.75484268
95Abnormal glycosylation (HP:0012345)1.75484268
96Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.75484268
97Abnormal protein N-linked glycosylation (HP:0012347)1.75484268
98Abnormality of renal resorption (HP:0011038)1.75133853
99Panhypogammaglobulinemia (HP:0003139)1.74550576
100Concave nail (HP:0001598)1.74479252

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K24.51556573
2TESK24.27503640
3ZAK3.89458932
4TXK3.40790233
5INSRR3.12176337
6TLK13.02249943
7CDK192.57194624
8GRK12.48913262
9VRK22.40009944
10SCYL22.36888468
11KDR2.31786304
12PLK42.23651049
13NUAK12.13079681
14VRK12.10769475
15BMPR22.04952693
16FRK1.96582496
17TAOK31.92528984
18TEC1.90403866
19ADRBK21.89964476
20MST41.84652976
21MAP3K121.64667751
22ITK1.56923749
23BUB11.50667696
24ERBB31.50100702
25TRPM71.37779753
26PIK3CG1.27372242
27TAF11.24200063
28PBK1.18964028
29PLK21.13007318
30SRPK11.12410519
31TESK11.07010011
32SYK1.06342621
33BCKDK1.01205637
34NEK10.97151759
35PLK30.96769005
36EIF2AK30.94201425
37KIT0.92731976
38PRKCQ0.90065049
39BTK0.86630129
40CDC70.83444335
41IKBKB0.82965231
42MYLK0.79932221
43WNK30.79868566
44RIPK40.78208358
45WNK40.77705121
46MKNK10.77657678
47CSF1R0.75084852
48PASK0.74199662
49MAP3K100.72949714
50MAP4K10.71891040
51OXSR10.69298828
52PLK10.68951129
53PINK10.67461005
54CDK30.67329059
55GRK60.65181259
56MAP2K60.63644130
57CDK80.62868717
58JAK30.62503567
59LCK0.60579303
60NME10.57756080
61TRIM280.57506495
62BMPR1B0.57322082
63LYN0.56593450
64DAPK10.55810930
65WEE10.55332550
66GRK70.54794061
67RPS6KA50.53645038
68MAPK130.53241052
69IGF1R0.53133195
70PTK2B0.48319102
71ROCK10.46377862
72OBSCN0.45510862
73PDK20.45182789
74MUSK0.44470794
75AURKB0.43870225
76EIF2AK20.40999663
77PRKCE0.39514037
78FLT30.39109864
79PRKACA0.38208292
80IKBKE0.37837645
81MAPK70.37814975
82MAPKAPK50.37296162
83ATR0.35259698
84ADRBK10.35190108
85PRKCB0.34481755
86PRKCA0.34294086
87ZAP700.34133248
88TIE10.33747221
89CSNK2A10.33623408
90HCK0.33236047
91BCR0.31135863
92STK390.28250532
93PRKG10.27899029
94CSNK2A20.27717398
95RPS6KA40.27339233
96PIM10.27078679
97ALK0.27031611
98CDK70.26220074
99STK38L0.25592569
100TNK20.24954690

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.25113511
2Primary immunodeficiency_Homo sapiens_hsa053403.37613665
3Asthma_Homo sapiens_hsa053103.15214508
4Allograft rejection_Homo sapiens_hsa053303.05191874
5Oxidative phosphorylation_Homo sapiens_hsa001902.96514765
6Autoimmune thyroid disease_Homo sapiens_hsa053202.95715947
7Graft-versus-host disease_Homo sapiens_hsa053322.86427963
8Type I diabetes mellitus_Homo sapiens_hsa049402.67685044
9Parkinsons disease_Homo sapiens_hsa050122.51636121
10Intestinal immune network for IgA production_Homo sapiens_hsa046722.41135173
11Protein export_Homo sapiens_hsa030602.33205304
12Homologous recombination_Homo sapiens_hsa034402.22680793
13Ribosome_Homo sapiens_hsa030102.12192636
14RNA polymerase_Homo sapiens_hsa030202.01741074
15Antigen processing and presentation_Homo sapiens_hsa046121.87718804
16Phototransduction_Homo sapiens_hsa047441.86307057
17Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.78166375
18Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.73906345
19Huntingtons disease_Homo sapiens_hsa050161.59162206
20Fanconi anemia pathway_Homo sapiens_hsa034601.57194301
21RNA degradation_Homo sapiens_hsa030181.52367930
22Alzheimers disease_Homo sapiens_hsa050101.50536745
23Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.50163894
24Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.48257784
25Basal transcription factors_Homo sapiens_hsa030221.46740529
26Olfactory transduction_Homo sapiens_hsa047401.45425077
27Hematopoietic cell lineage_Homo sapiens_hsa046401.45228313
28Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.25449271
29Systemic lupus erythematosus_Homo sapiens_hsa053221.24424496
30Cardiac muscle contraction_Homo sapiens_hsa042601.24133314
31DNA replication_Homo sapiens_hsa030301.23893904
32Rheumatoid arthritis_Homo sapiens_hsa053231.21991527
33Propanoate metabolism_Homo sapiens_hsa006401.17553645
34Retinol metabolism_Homo sapiens_hsa008301.16529257
35One carbon pool by folate_Homo sapiens_hsa006701.13391188
36Purine metabolism_Homo sapiens_hsa002301.12134098
37Mismatch repair_Homo sapiens_hsa034301.10007939
38Caffeine metabolism_Homo sapiens_hsa002321.09290081
39Peroxisome_Homo sapiens_hsa041461.07603097
40Linoleic acid metabolism_Homo sapiens_hsa005911.06296563
41Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.00805258
42Pyrimidine metabolism_Homo sapiens_hsa002400.96841905
43Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.95670277
44Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.93840964
45Spliceosome_Homo sapiens_hsa030400.91747719
46Primary bile acid biosynthesis_Homo sapiens_hsa001200.91337946
47Non-homologous end-joining_Homo sapiens_hsa034500.89657198
48Viral myocarditis_Homo sapiens_hsa054160.88292084
49Butanoate metabolism_Homo sapiens_hsa006500.86116821
50RNA transport_Homo sapiens_hsa030130.84170551
51Maturity onset diabetes of the young_Homo sapiens_hsa049500.82859635
52Nucleotide excision repair_Homo sapiens_hsa034200.75825400
53T cell receptor signaling pathway_Homo sapiens_hsa046600.74630989
54Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.74192690
55Base excision repair_Homo sapiens_hsa034100.70481380
56Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.70332672
57Nitrogen metabolism_Homo sapiens_hsa009100.70216514
58Tryptophan metabolism_Homo sapiens_hsa003800.69074794
59Drug metabolism - other enzymes_Homo sapiens_hsa009830.68579911
60alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.66308888
61Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.64405429
62Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.64283842
63Arachidonic acid metabolism_Homo sapiens_hsa005900.63809735
64Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.61858044
65Chemical carcinogenesis_Homo sapiens_hsa052040.58371914
66Regulation of autophagy_Homo sapiens_hsa041400.58290893
67SNARE interactions in vesicular transport_Homo sapiens_hsa041300.57561164
68Renin-angiotensin system_Homo sapiens_hsa046140.57195325
69Metabolic pathways_Homo sapiens_hsa011000.55923305
70Cysteine and methionine metabolism_Homo sapiens_hsa002700.54777631
71Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.54694907
72Steroid hormone biosynthesis_Homo sapiens_hsa001400.54447806
73Herpes simplex infection_Homo sapiens_hsa051680.52540194
74Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.49947538
75Staphylococcus aureus infection_Homo sapiens_hsa051500.49084700
76Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.49037826
77ABC transporters_Homo sapiens_hsa020100.48395824
78Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.47363625
79Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.46959315
80Salivary secretion_Homo sapiens_hsa049700.45818671
81Leishmaniasis_Homo sapiens_hsa051400.44142587
82Glutathione metabolism_Homo sapiens_hsa004800.43730847
83Fatty acid biosynthesis_Homo sapiens_hsa000610.42106799
84Measles_Homo sapiens_hsa051620.41101475
85Taste transduction_Homo sapiens_hsa047420.40661159
86Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.37215380
87Ether lipid metabolism_Homo sapiens_hsa005650.35440541
88Malaria_Homo sapiens_hsa051440.33586961
89Transcriptional misregulation in cancer_Homo sapiens_hsa052020.32563914
90Jak-STAT signaling pathway_Homo sapiens_hsa046300.31953109
91Fat digestion and absorption_Homo sapiens_hsa049750.31803837
92Epstein-Barr virus infection_Homo sapiens_hsa051690.31133748
93NF-kappa B signaling pathway_Homo sapiens_hsa040640.28302620
94beta-Alanine metabolism_Homo sapiens_hsa004100.25920347
95Pentose and glucuronate interconversions_Homo sapiens_hsa000400.25373898
96NOD-like receptor signaling pathway_Homo sapiens_hsa046210.23438982
97Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.23033099
98Sulfur metabolism_Homo sapiens_hsa009200.22638766
99Fatty acid degradation_Homo sapiens_hsa000710.22524713
100Oocyte meiosis_Homo sapiens_hsa041140.22471230

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »