HNRNPA1P16

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosome assembly (GO:0042255)7.68396347
2DNA unwinding involved in DNA replication (GO:0006268)5.15729920
3ncRNA catabolic process (GO:0034661)4.57746799
4regulation of DNA endoreduplication (GO:0032875)4.34461050
5nuclear pore complex assembly (GO:0051292)4.30835022
6mitotic sister chromatid cohesion (GO:0007064)4.28638605
7ribosomal large subunit biogenesis (GO:0042273)4.19287519
8DNA replication checkpoint (GO:0000076)4.16516914
9DNA strand elongation (GO:0022616)4.16361893
10urate metabolic process (GO:0046415)4.14371746
11DNA strand elongation involved in DNA replication (GO:0006271)4.06501249
12stress granule assembly (GO:0034063)4.01898211
13mitotic sister chromatid segregation (GO:0000070)3.99245483
14establishment of integrated proviral latency (GO:0075713)3.93584664
15somatic diversification of immunoglobulins involved in immune response (GO:0002208)3.88320785
16isotype switching (GO:0045190)3.88320785
17somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)3.88320785
18DNA replication-dependent nucleosome organization (GO:0034723)3.86534258
19DNA replication-dependent nucleosome assembly (GO:0006335)3.86534258
20DNA topological change (GO:0006265)3.86421211
21DNA double-strand break processing (GO:0000729)3.84638606
22L-serine metabolic process (GO:0006563)3.73745429
23nuclear pore organization (GO:0006999)3.71842525
24formation of translation preinitiation complex (GO:0001731)3.68094363
25sister chromatid segregation (GO:0000819)3.67655147
26mitotic chromosome condensation (GO:0007076)3.64706072
27folic acid-containing compound biosynthetic process (GO:0009396)3.64252909
28mitotic nuclear envelope disassembly (GO:0007077)3.60817514
29positive regulation of protein homodimerization activity (GO:0090073)3.57728316
30ribosome biogenesis (GO:0042254)3.56499353
31somatic diversification of immune receptors via somatic mutation (GO:0002566)3.55449976
32somatic hypermutation of immunoglobulin genes (GO:0016446)3.55449976
33IMP biosynthetic process (GO:0006188)3.53842038
34resolution of meiotic recombination intermediates (GO:0000712)3.53430334
35pentose-phosphate shunt (GO:0006098)3.52150115
36DNA geometric change (GO:0032392)3.50378149
37NADPH regeneration (GO:0006740)3.49630047
38DNA catabolic process, exonucleolytic (GO:0000738)3.48454678
39DNA duplex unwinding (GO:0032508)3.47967093
40DNA replication initiation (GO:0006270)3.45513678
41regulation of activation of Janus kinase activity (GO:0010533)3.44561727
42purine nucleobase metabolic process (GO:0006144)3.41697194
43somatic recombination of immunoglobulin gene segments (GO:0016447)3.40123369
44tRNA methylation (GO:0030488)3.39294326
45rRNA modification (GO:0000154)3.33202148
467-methylguanosine mRNA capping (GO:0006370)3.26847250
47protein localization to kinetochore (GO:0034501)3.26656088
48IMP metabolic process (GO:0046040)3.26149138
49negative regulation of DNA-dependent DNA replication (GO:2000104)3.23769209
50DNA damage response, detection of DNA damage (GO:0042769)3.23327468
51telomere maintenance via semi-conservative replication (GO:0032201)3.22700743
52membrane disassembly (GO:0030397)3.19114111
53nuclear envelope disassembly (GO:0051081)3.19114111
54negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.18748700
55pseudouridine synthesis (GO:0001522)3.17244179
56ribonucleoprotein complex biogenesis (GO:0022613)3.16940819
577-methylguanosine RNA capping (GO:0009452)3.16248962
58RNA capping (GO:0036260)3.16248962
59kinetochore organization (GO:0051383)3.13372302
60pore complex assembly (GO:0046931)3.12042664
61protein localization to chromosome, centromeric region (GO:0071459)3.10191777
62somatic diversification of immunoglobulins (GO:0016445)3.06668485
63rRNA methylation (GO:0031167)3.04402129
64mitotic spindle checkpoint (GO:0071174)3.03024434
65positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)3.02770916
66positive regulation of translational initiation (GO:0045948)3.01735960
67pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174)3.01173111
68UMP metabolic process (GO:0046049)3.01173111
69pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173)3.01173111
70UMP biosynthetic process (GO:0006222)3.01173111
71DNA conformation change (GO:0071103)3.00075062
72non-recombinational repair (GO:0000726)2.99832280
73double-strand break repair via nonhomologous end joining (GO:0006303)2.99832280
74serine family amino acid biosynthetic process (GO:0009070)2.95550377
75establishment of viral latency (GO:0019043)2.95027348
76pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)2.94926492
77purine nucleobase biosynthetic process (GO:0009113)2.94441764
78nucleobase biosynthetic process (GO:0046112)2.91648780
79spindle checkpoint (GO:0031577)2.91127428
80positive regulation of G1/S transition of mitotic cell cycle (GO:1900087)2.90689762
81regulation of centriole replication (GO:0046599)2.90479300
82somatic cell DNA recombination (GO:0016444)2.88817753
83somatic diversification of immune receptors via germline recombination within a single locus (GO:0002.88817753
84tRNA aminoacylation for protein translation (GO:0006418)2.87966963
85histone H2B ubiquitination (GO:0033523)2.86988279
86replication fork processing (GO:0031297)2.85713197
87meiotic chromosome segregation (GO:0045132)2.85109929
88negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.83842455
89positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.83348233
90regulation of mitotic spindle organization (GO:0060236)2.82100953
91amino acid activation (GO:0043038)2.82085030
92tRNA aminoacylation (GO:0043039)2.82085030
93mitotic recombination (GO:0006312)2.81839183
94exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.81233475
95telomere maintenance via recombination (GO:0000722)2.80977839
96mRNA splicing, via spliceosome (GO:0000398)2.80039090
97RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.80039090
98maturation of 5.8S rRNA (GO:0000460)2.78837226
99negative regulation of mRNA processing (GO:0050686)2.78670103
100RNA splicing, via transesterification reactions (GO:0000375)2.78627572

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.57310339
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.06920073
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.88465114
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.77531866
5HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.66629918
6FOXM1_23109430_ChIP-Seq_U2OS_Human3.58672732
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.22756539
8GABP_17652178_ChIP-ChIP_JURKAT_Human3.12526540
9FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.09073767
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.93850630
11CREB1_15753290_ChIP-ChIP_HEK293T_Human2.91141863
12EST1_17652178_ChIP-ChIP_JURKAT_Human2.90196534
13ELF1_17652178_ChIP-ChIP_JURKAT_Human2.80661733
14MYC_18358816_ChIP-ChIP_MESCs_Mouse2.78026089
15MYC_19030024_ChIP-ChIP_MESCs_Mouse2.72651499
16MYC_19079543_ChIP-ChIP_MESCs_Mouse2.66869421
17ETS1_20019798_ChIP-Seq_JURKAT_Human2.63122631
18KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.38063134
19MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.37343749
20DCP1A_22483619_ChIP-Seq_HELA_Human2.25775780
21XRN2_22483619_ChIP-Seq_HELA_Human2.25736101
22TTF2_22483619_ChIP-Seq_HELA_Human2.19724556
23FOXP3_21729870_ChIP-Seq_TREG_Human2.19375308
24NELFA_20434984_ChIP-Seq_ESCs_Mouse2.17145398
25CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.17016976
26E2F1_21310950_ChIP-Seq_MCF-7_Human2.16837709
27ELK1_19687146_ChIP-ChIP_HELA_Human2.15284033
28THAP11_20581084_ChIP-Seq_MESCs_Mouse2.15158377
29YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.07455010
30VDR_23849224_ChIP-Seq_CD4+_Human2.02346843
31ESR1_15608294_ChIP-ChIP_MCF-7_Human2.00226390
32PADI4_21655091_ChIP-ChIP_MCF-7_Human1.98158003
33MYCN_18555785_ChIP-Seq_MESCs_Mouse1.98093358
34SALL1_21062744_ChIP-ChIP_HESCs_Human1.93633396
35SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.92926798
36GABP_19822575_ChIP-Seq_HepG2_Human1.89107920
37EGR1_19374776_ChIP-ChIP_THP-1_Human1.86655694
38POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.84695918
39HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.82109242
40SRF_21415370_ChIP-Seq_HL-1_Mouse1.79664179
41AR_21909140_ChIP-Seq_LNCAP_Human1.77939506
42E2F1_18555785_ChIP-Seq_MESCs_Mouse1.76890090
43FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.75141631
44HOXB4_20404135_ChIP-ChIP_EML_Mouse1.69570700
45NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.67586073
46KDM5A_27292631_Chip-Seq_BREAST_Human1.66995654
47MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.62228295
48ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.61507049
49PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.61306594
50ZFX_18555785_ChIP-Seq_MESCs_Mouse1.58698234
51E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.55106424
52TFEB_21752829_ChIP-Seq_HELA_Human1.54750114
53PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.54059886
54SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.53939663
55MYC_22102868_ChIP-Seq_BL_Human1.52952894
56CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.49902267
57NOTCH1_21737748_ChIP-Seq_TLL_Human1.41036626
58MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.40861373
59NANOG_18555785_ChIP-Seq_MESCs_Mouse1.40415250
60E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.38159885
61CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.34593856
62TP63_19390658_ChIP-ChIP_HaCaT_Human1.28095302
63ERG_20887958_ChIP-Seq_HPC-7_Mouse1.27957126
64DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.26393450
65CIITA_25753668_ChIP-Seq_RAJI_Human1.24850205
66YY1_21170310_ChIP-Seq_MESCs_Mouse1.20674683
67CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.17984170
68SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.15667670
69ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.15411303
70CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.15106578
71TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.05544390
72ZNF274_21170338_ChIP-Seq_K562_Hela1.04510399
73NANOG_21062744_ChIP-ChIP_HESCs_Human1.00747635
74MYC_18940864_ChIP-ChIP_HL60_Human1.00380160
75PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.99106910
76CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.98263517
77DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.95078734
78SOX17_20123909_ChIP-Seq_XEN_Mouse0.92733109
79ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.91569610
80GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.91519723
81SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.91374986
82BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.91258536
83ZNF263_19887448_ChIP-Seq_K562_Human0.89214025
84CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.87937804
85POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.85564175
86KLF4_18555785_ChIP-Seq_MESCs_Mouse0.85254554
87FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.84230887
88CHD1_26751641_Chip-Seq_LNCaP_Human0.84058257
89SPI1_23547873_ChIP-Seq_NB4_Human0.81866816
90EWS_26573619_Chip-Seq_HEK293_Human0.81238749
91ELF5_23300383_ChIP-Seq_T47D_Human0.78407658
92CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.78285472
93CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.77155678
94IRF1_19129219_ChIP-ChIP_H3396_Human0.74609806
95KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.74513668
96STAT3_1855785_ChIP-Seq_MESCs_Mouse0.69913412
97FUS_26573619_Chip-Seq_HEK293_Human0.69480740
98SOX2_18555785_ChIP-Seq_MESCs_Mouse0.68567881
99PKCTHETA_26484144_Chip-Seq_BREAST_Human0.65148234
100GATA4_21415370_ChIP-Seq_HL-1_Mouse0.63907409

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability4.87951908
2MP0000372_irregular_coat_pigmentation4.59751686
3MP0003693_abnormal_embryo_hatching4.48381751
4MP0008057_abnormal_DNA_replication4.39369140
5MP0008007_abnormal_cellular_replicative4.27212167
6MP0008058_abnormal_DNA_repair3.75493354
7MP0003111_abnormal_nucleus_morphology3.74538905
8MP0003077_abnormal_cell_cycle3.34755075
9MP0004957_abnormal_blastocyst_morpholog2.96853098
10MP0002009_preneoplasia2.76517593
11MP0006292_abnormal_olfactory_placode2.40266125
12MP0002102_abnormal_ear_morphology2.37600491
13MP0009697_abnormal_copulation2.36586941
14MP0008932_abnormal_embryonic_tissue2.32951528
15MP0004147_increased_porphyrin_level2.21156812
16MP0001730_embryonic_growth_arrest2.09176342
17MP0005174_abnormal_tail_pigmentation2.06567682
18MP0003136_yellow_coat_color2.02579356
19MP0002163_abnormal_gland_morphology1.95923901
20MP0000490_abnormal_crypts_of1.77058258
21MP0003937_abnormal_limbs/digits/tail_de1.71520161
22MP0003786_premature_aging1.71033800
23MP0002396_abnormal_hematopoietic_system1.70643932
24MP0005451_abnormal_body_composition1.67809284
25MP0000350_abnormal_cell_proliferation1.60029686
26MP0009333_abnormal_splenocyte_physiolog1.55041388
27MP0005408_hypopigmentation1.52180824
28MP0001348_abnormal_lacrimal_gland1.51579518
29MP0008995_early_reproductive_senescence1.51425625
30MP0002837_dystrophic_cardiac_calcinosis1.49513440
31MP0003806_abnormal_nucleotide_metabolis1.48971369
32MP0001697_abnormal_embryo_size1.48794272
33MP0002095_abnormal_skin_pigmentation1.43481216
34MP0005266_abnormal_metabolism1.38876251
35MP0003763_abnormal_thymus_physiology1.31655057
36MP0000371_diluted_coat_color1.31274949
37MP0002249_abnormal_larynx_morphology1.30217532
38MP0002080_prenatal_lethality1.26485593
39MP0004084_abnormal_cardiac_muscle1.26316929
40MP0000313_abnormal_cell_death1.26164670
41MP0003718_maternal_effect1.24787813
42MP0006035_abnormal_mitochondrial_morpho1.18619226
43MP0002938_white_spotting1.17076833
44MP0005645_abnormal_hypothalamus_physiol1.16298322
45MP0001672_abnormal_embryogenesis/_devel1.14451663
46MP0005380_embryogenesis_phenotype1.14451663
47MP0001293_anophthalmia1.12738328
48MP0005379_endocrine/exocrine_gland_phen1.12681634
49MP0006036_abnormal_mitochondrial_physio1.11292056
50MP0002019_abnormal_tumor_incidence1.09661692
51MP0002085_abnormal_embryonic_tissue1.04226328
52MP0000015_abnormal_ear_pigmentation1.00426477
53MP0006072_abnormal_retinal_apoptosis1.00418288
54MP0004808_abnormal_hematopoietic_stem0.96580700
55MP0004197_abnormal_fetal_growth/weight/0.95371685
56MP0006138_congestive_heart_failure0.94879362
57MP0000681_abnormal_thyroid_gland0.94379224
58MP0004185_abnormal_adipocyte_glucose0.93493934
59MP0002084_abnormal_developmental_patter0.91391151
60MP0001764_abnormal_homeostasis0.90226302
61MP0003984_embryonic_growth_retardation0.89821084
62MP0000678_abnormal_parathyroid_gland0.89720525
63MP0009384_cardiac_valve_regurgitation0.88890271
64MP0009278_abnormal_bone_marrow0.88703930
65MP0001873_stomach_inflammation0.88328412
66MP0004782_abnormal_surfactant_physiolog0.88086904
67MP0002086_abnormal_extraembryonic_tissu0.87394779
68MP0002088_abnormal_embryonic_growth/wei0.85525622
69MP0001929_abnormal_gametogenesis0.85172921
70MP0002210_abnormal_sex_determination0.82897082
71MP0002166_altered_tumor_susceptibility0.76928435
72MP0009115_abnormal_fat_cell0.75361381
73MP0000703_abnormal_thymus_morphology0.75013036
74MP0002398_abnormal_bone_marrow0.71814753
75MP0002075_abnormal_coat/hair_pigmentati0.71505086
76MP0003567_abnormal_fetal_cardiomyocyte0.71210751
77MP0003646_muscle_fatigue0.69258875
78MP0010234_abnormal_vibrissa_follicle0.68743917
79MP0002177_abnormal_outer_ear0.67495759
80MP0002006_tumorigenesis0.67082244
81MP0002132_abnormal_respiratory_system0.65052310
82MP0000358_abnormal_cell_content/0.64087552
83MP0005220_abnormal_exocrine_pancreas0.63985283
84MP0009250_abnormal_appendicular_skeleto0.63001448
85MP0005075_abnormal_melanosome_morpholog0.62052617
86MP0009672_abnormal_birth_weight0.61943888
87MP0004381_abnormal_hair_follicle0.61821234
88MP0004233_abnormal_muscle_weight0.60629879
89MP0001145_abnormal_male_reproductive0.60223298
90MP0002090_abnormal_vision0.59043887
91MP0003699_abnormal_female_reproductive0.58531351
92MP0005084_abnormal_gallbladder_morpholo0.57435545
93MP0003935_abnormal_craniofacial_develop0.57092143
94MP0002722_abnormal_immune_system0.56380996
95MP0003011_delayed_dark_adaptation0.55344616
96MP0008789_abnormal_olfactory_epithelium0.54958814
97MP0000689_abnormal_spleen_morphology0.54586575
98MP0002092_abnormal_eye_morphology0.53799861
99MP0002932_abnormal_joint_morphology0.52780351
100MP0005319_abnormal_enzyme/_coenzyme0.52487977

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the preputium (HP:0100587)5.01434944
2Reduced antithrombin III activity (HP:0001976)3.72085856
3Aplasia/Hypoplasia of the uvula (HP:0010293)3.43713101
4Type I transferrin isoform profile (HP:0003642)3.34731557
5Meckel diverticulum (HP:0002245)3.34033527
6Increased nuchal translucency (HP:0010880)3.32328962
7Abnormality of placental membranes (HP:0011409)3.10319251
8Amniotic constriction ring (HP:0009775)3.10319251
9Chromsome breakage (HP:0040012)3.09612915
10Abnormality of the intrinsic pathway (HP:0010989)3.08299554
11Chromosomal breakage induced by crosslinking agents (HP:0003221)3.07849235
12Abnormality of chromosome stability (HP:0003220)3.07823320
13Abnormality of the ileum (HP:0001549)3.07566102
14Birth length less than 3rd percentile (HP:0003561)3.04392534
15Myelodysplasia (HP:0002863)3.04266590
16Poikiloderma (HP:0001029)2.97571288
17Rhabdomyosarcoma (HP:0002859)2.96683324
18Abnormality of the carotid arteries (HP:0005344)2.94584534
19Volvulus (HP:0002580)2.92889013
20Abnormality of pyrimidine metabolism (HP:0004353)2.84262755
21Rhabdomyolysis (HP:0003201)2.83093978
22Hypoplastic pelvis (HP:0008839)2.78898702
23Respiratory difficulties (HP:0002880)2.68320772
24Microvesicular hepatic steatosis (HP:0001414)2.59259604
25Ependymoma (HP:0002888)2.56576254
26Duodenal stenosis (HP:0100867)2.55718886
27Small intestinal stenosis (HP:0012848)2.55718886
28Abnormality of the anterior horn cell (HP:0006802)2.51208360
29Degeneration of anterior horn cells (HP:0002398)2.51208360
30Ankyloglossia (HP:0010296)2.50814897
31Increased serum pyruvate (HP:0003542)2.45369602
32Trismus (HP:0000211)2.45132418
33Abnormality of glycolysis (HP:0004366)2.43033309
34Proximal placement of thumb (HP:0009623)2.36176307
35Medulloblastoma (HP:0002885)2.32233567
36Bone marrow hypocellularity (HP:0005528)2.31132108
37Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.30887007
38Abnormal protein N-linked glycosylation (HP:0012347)2.30887007
39Abnormal protein glycosylation (HP:0012346)2.30887007
40Abnormal glycosylation (HP:0012345)2.30887007
41Pustule (HP:0200039)2.28583503
42Biliary tract neoplasm (HP:0100574)2.25912344
43Insomnia (HP:0100785)2.24816213
44Urethral obstruction (HP:0000796)2.24130626
45Breech presentation (HP:0001623)2.21509477
46Clubbing of toes (HP:0100760)2.20171654
47Cerebral palsy (HP:0100021)2.19588106
48Adrenal hypoplasia (HP:0000835)2.16713653
49Choanal atresia (HP:0000453)2.13792486
50Oral leukoplakia (HP:0002745)2.13702334
51Abnormal gallbladder physiology (HP:0012438)2.13148058
52Cholecystitis (HP:0001082)2.13148058
53Colon cancer (HP:0003003)2.11722129
54Acute encephalopathy (HP:0006846)2.09837433
55Deviation of the thumb (HP:0009603)2.09163284
56Cortical dysplasia (HP:0002539)2.08788595
57Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.07389292
58Overriding aorta (HP:0002623)2.07135732
59Biconcave vertebral bodies (HP:0004586)2.06690066
60Absent thumb (HP:0009777)2.04812118
61Hypoplasia of the capital femoral epiphysis (HP:0003090)2.04372228
62Reticulocytosis (HP:0001923)2.04001939
63Multiple enchondromatosis (HP:0005701)2.03954480
64Abnormality of reticulocytes (HP:0004312)1.97147545
65Abnormality of DNA repair (HP:0003254)1.97135273
66J-shaped sella turcica (HP:0002680)1.95673178
67Hyperammonemia (HP:0001987)1.95480038
68Elfin facies (HP:0004428)1.95192737
69Periodontitis (HP:0000704)1.95175553
70Abnormality of the labia minora (HP:0012880)1.95105620
71Hypoparathyroidism (HP:0000829)1.92704617
72Cafe-au-lait spot (HP:0000957)1.91934400
73Long clavicles (HP:0000890)1.91248064
74Abnormal number of incisors (HP:0011064)1.88459072
75Cholelithiasis (HP:0001081)1.87210791
76Abnormalities of placenta or umbilical cord (HP:0001194)1.87013751
77Duplicated collecting system (HP:0000081)1.84373924
78Neoplasm of the pancreas (HP:0002894)1.84296784
79Abnormality of the musculature of the pelvis (HP:0001469)1.83913497
80Abnormality of the hip-girdle musculature (HP:0001445)1.83913497
81Abnormality of oral frenula (HP:0000190)1.83740440
82Abnormality of the pons (HP:0007361)1.83218229
83Abnormality of the duodenum (HP:0002246)1.82878720
84Increased intramyocellular lipid droplets (HP:0012240)1.82869047
85Reticulocytopenia (HP:0001896)1.82677160
86Horseshoe kidney (HP:0000085)1.81125728
87Prominent metopic ridge (HP:0005487)1.80211119
88Acute myeloid leukemia (HP:0004808)1.78986140
89Glioma (HP:0009733)1.78961128
90Cerebral edema (HP:0002181)1.78915091
91Redundant skin (HP:0001582)1.77219377
92Abnormal biliary tract morphology (HP:0012440)1.77160256
93Rough bone trabeculation (HP:0100670)1.76564963
94Tracheoesophageal fistula (HP:0002575)1.76277301
95Agnosia (HP:0010524)1.73550945
96Severe short stature (HP:0003510)1.73535174
97Arteriovenous malformation (HP:0100026)1.73174590
98Deep palmar crease (HP:0006191)1.72482530
99Hyperglycinuria (HP:0003108)1.72388664
100Abnormal gallbladder morphology (HP:0012437)1.70582046

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.61292166
2EIF2AK33.82098923
3EIF2AK13.54429787
4TSSK63.24914752
5TTK3.09233001
6SRPK12.84633052
7BUB12.77007271
8NEK12.69096892
9TRIM282.66609209
10ZAK2.57238032
11PASK2.32448073
12MAP3K142.31648950
13CDK32.28981054
14PBK2.26487934
15STK162.20863071
16MKNK12.13746256
17VRK22.10473354
18WEE12.04858058
19BCKDK1.94995734
20PLK31.92420950
21PLK41.68914454
22EIF2AK21.54165531
23CHEK21.50426026
24ATR1.43759990
25PLK11.35776271
26STK41.33601642
27CDK121.29830581
28AURKB1.25513545
29BRD41.23389123
30MKNK21.19311889
31SIK31.17621463
32CHEK11.10911602
33VRK11.05287838
34BRSK21.03419404
35ATM1.01282631
36SMG11.00520311
37CDK71.00476971
38KSR10.99578992
39ALK0.98479880
40RPS6KB20.98355821
41GRK60.92920986
42NME20.92194813
43BCR0.91600735
44MAP4K20.90733638
45SCYL20.89257271
46WNK40.88868976
47CDK40.87952226
48ERBB30.86592254
49SYK0.84872763
50BRSK10.84703198
51NME10.82795750
52MST40.79525593
53CDK20.78827276
54PRKD30.77520507
55CSNK1E0.73849333
56CDK80.72124515
57YES10.71694510
58CDK10.70594112
59AKT20.70569436
60CLK10.67925228
61WNK10.67844703
62RPS6KA40.62875024
63NUAK10.61375841
64CAMK1D0.59337103
65CDK60.57968869
66MAP3K80.57925256
67PRKDC0.57229509
68BMPR1B0.57118576
69RAF10.56788509
70RIPK40.55805535
71CSF1R0.55530289
72CAMKK20.54911491
73CSNK2A20.54714360
74ERBB40.53631891
75IRAK30.52690469
76CSNK1G30.51863725
77CSNK2A10.51731169
78PRKCI0.50930618
79PKN20.50793788
80PNCK0.49700148
81TAF10.48945969
82NEK20.48883604
83JAK30.46887346
84ITK0.46044429
85PIM10.45981838
86STK100.45010386
87PLK20.43305927
88IRAK20.43096482
89PIK3CG0.41486520
90TEC0.41225898
91STK30.39664558
92CAMK1G0.38695668
93CSNK1G10.35789840
94AURKA0.34052751
95CDK180.31640714
96MAP3K130.27974620
97TNK20.27075063
98GSK3B0.27007729
99PAK20.26551868
100CDK11A0.25372183

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.40544262
2DNA replication_Homo sapiens_hsa030303.64554259
3Mismatch repair_Homo sapiens_hsa034303.62750453
4Proteasome_Homo sapiens_hsa030503.04741659
5Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.97900948
6Non-homologous end-joining_Homo sapiens_hsa034502.87987923
7Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.87649545
8RNA transport_Homo sapiens_hsa030132.80530319
9Spliceosome_Homo sapiens_hsa030402.76567713
10Fanconi anemia pathway_Homo sapiens_hsa034602.75311643
11One carbon pool by folate_Homo sapiens_hsa006702.64257821
12Homologous recombination_Homo sapiens_hsa034402.55274535
13Nucleotide excision repair_Homo sapiens_hsa034202.44954339
14RNA degradation_Homo sapiens_hsa030182.43736530
15Cell cycle_Homo sapiens_hsa041102.22454301
16Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.21661198
17RNA polymerase_Homo sapiens_hsa030202.20484878
18Biosynthesis of amino acids_Homo sapiens_hsa012302.04182741
19Pyrimidine metabolism_Homo sapiens_hsa002402.01336419
20Base excision repair_Homo sapiens_hsa034102.01201941
21Basal transcription factors_Homo sapiens_hsa030221.95267487
22Cysteine and methionine metabolism_Homo sapiens_hsa002701.89656566
23Selenocompound metabolism_Homo sapiens_hsa004501.84641282
24mRNA surveillance pathway_Homo sapiens_hsa030151.82768828
25Pentose phosphate pathway_Homo sapiens_hsa000301.69507265
26Pyruvate metabolism_Homo sapiens_hsa006201.66093206
27Carbon metabolism_Homo sapiens_hsa012001.61161402
28Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.52034316
29Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.49663995
30Ribosome_Homo sapiens_hsa030101.44244990
31Purine metabolism_Homo sapiens_hsa002301.40423399
32Propanoate metabolism_Homo sapiens_hsa006401.36902460
33Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.32409271
34Steroid biosynthesis_Homo sapiens_hsa001001.30337390
35Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.28016872
36Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.25987388
372-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.21612166
38Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.13950631
39N-Glycan biosynthesis_Homo sapiens_hsa005101.06094656
40Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.05041526
41Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.97868839
42Fatty acid metabolism_Homo sapiens_hsa012120.96580105
43Protein export_Homo sapiens_hsa030600.95903760
44Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.95764026
45Fatty acid elongation_Homo sapiens_hsa000620.93321101
46Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.89382632
47Vitamin B6 metabolism_Homo sapiens_hsa007500.85207050
48Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.84036029
49Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.72782794
50Epstein-Barr virus infection_Homo sapiens_hsa051690.71388963
51Glutathione metabolism_Homo sapiens_hsa004800.68951021
52p53 signaling pathway_Homo sapiens_hsa041150.65711462
53Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.64432829
54Oocyte meiosis_Homo sapiens_hsa041140.64387107
55Herpes simplex infection_Homo sapiens_hsa051680.62036918
56Pentose and glucuronate interconversions_Homo sapiens_hsa000400.60210677
57Drug metabolism - other enzymes_Homo sapiens_hsa009830.55519710
58MicroRNAs in cancer_Homo sapiens_hsa052060.55299568
59Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.54878747
60Metabolic pathways_Homo sapiens_hsa011000.52530770
61Caffeine metabolism_Homo sapiens_hsa002320.51083394
62Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.44518059
63Asthma_Homo sapiens_hsa053100.43696781
64Transcriptional misregulation in cancer_Homo sapiens_hsa052020.39127222
65Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.37375106
66Peroxisome_Homo sapiens_hsa041460.36764198
67Folate biosynthesis_Homo sapiens_hsa007900.35670568
68Lysine degradation_Homo sapiens_hsa003100.32061942
69Measles_Homo sapiens_hsa051620.28829321
70Apoptosis_Homo sapiens_hsa042100.28387797
71Butanoate metabolism_Homo sapiens_hsa006500.28136646
72Viral carcinogenesis_Homo sapiens_hsa052030.27198932
73Sulfur relay system_Homo sapiens_hsa041220.26355069
74Chronic myeloid leukemia_Homo sapiens_hsa052200.25399725
75Parkinsons disease_Homo sapiens_hsa050120.23331467
76Huntingtons disease_Homo sapiens_hsa050160.21704910
77Fatty acid biosynthesis_Homo sapiens_hsa000610.20673485
78Retinol metabolism_Homo sapiens_hsa008300.20656430
79Steroid hormone biosynthesis_Homo sapiens_hsa001400.20192368
80Primary immunodeficiency_Homo sapiens_hsa053400.17141103
81Arginine biosynthesis_Homo sapiens_hsa002200.16934476
82Allograft rejection_Homo sapiens_hsa053300.16577973
83Cyanoamino acid metabolism_Homo sapiens_hsa004600.16403661
84Jak-STAT signaling pathway_Homo sapiens_hsa046300.16378543
85Fructose and mannose metabolism_Homo sapiens_hsa000510.15812264
86Arginine and proline metabolism_Homo sapiens_hsa003300.15184626
87Fatty acid degradation_Homo sapiens_hsa000710.14243192
88Type I diabetes mellitus_Homo sapiens_hsa049400.14214862
89Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.14046958
90Oxidative phosphorylation_Homo sapiens_hsa001900.13827466
91Thyroid cancer_Homo sapiens_hsa052160.11769927
92NF-kappa B signaling pathway_Homo sapiens_hsa040640.11448765
93Sulfur metabolism_Homo sapiens_hsa009200.10236697
94Small cell lung cancer_Homo sapiens_hsa052220.09602181
95Hepatitis B_Homo sapiens_hsa051610.08579898
96Central carbon metabolism in cancer_Homo sapiens_hsa052300.05602555
97HTLV-I infection_Homo sapiens_hsa051660.05594488
98Autoimmune thyroid disease_Homo sapiens_hsa053200.05364092
99Legionellosis_Homo sapiens_hsa051340.05115064
100Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.04608212

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