

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.77806075 |
| 2 | regulation of memory T cell differentiation (GO:0043380) | 5.30455746 |
| 3 | DNA deamination (GO:0045006) | 5.08931107 |
| 4 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 4.89334271 |
| 5 | cellular response to interleukin-15 (GO:0071350) | 4.71195353 |
| 6 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 4.66882726 |
| 7 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 4.65645169 |
| 8 | cytidine deamination (GO:0009972) | 4.57750049 |
| 9 | cytidine metabolic process (GO:0046087) | 4.57750049 |
| 10 | cytidine catabolic process (GO:0006216) | 4.57750049 |
| 11 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.50331668 |
| 12 | regulation of chronic inflammatory response (GO:0002676) | 4.45630036 |
| 13 | regulation of vitamin D biosynthetic process (GO:0060556) | 4.37508331 |
| 14 | Peyers patch development (GO:0048541) | 4.34546414 |
| 15 | mucosal-associated lymphoid tissue development (GO:0048537) | 4.34546414 |
| 16 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 4.16796481 |
| 17 | regulation of T cell mediated cytotoxicity (GO:0001914) | 4.14415827 |
| 18 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.12086809 |
| 19 | regulation of regulatory T cell differentiation (GO:0045589) | 4.00469287 |
| 20 | positive regulation of cell killing (GO:0031343) | 4.00242338 |
| 21 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.96951942 |
| 22 | positive regulation of cell fate commitment (GO:0010455) | 3.94224819 |
| 23 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.93476662 |
| 24 | response to interleukin-15 (GO:0070672) | 3.92406009 |
| 25 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 3.88424217 |
| 26 | negative regulation of cell killing (GO:0031342) | 3.76624775 |
| 27 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.76624775 |
| 28 | natural killer cell differentiation (GO:0001779) | 3.72162893 |
| 29 | positive regulation of osteoclast differentiation (GO:0045672) | 3.71526774 |
| 30 | base-excision repair, AP site formation (GO:0006285) | 3.68069287 |
| 31 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.64359236 |
| 32 | sequestering of actin monomers (GO:0042989) | 3.63450225 |
| 33 | regulation of tyrosine phosphorylation of Stat1 protein (GO:0042510) | 3.63090877 |
| 34 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.60181376 |
| 35 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.59957269 |
| 36 | regulation of cell killing (GO:0031341) | 3.59439419 |
| 37 | positive regulation of interleukin-12 production (GO:0032735) | 3.54060337 |
| 38 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 3.53807384 |
| 39 | regulation of vitamin metabolic process (GO:0030656) | 3.53090958 |
| 40 | leukocyte aggregation (GO:0070486) | 3.31685294 |
| 41 | positive regulation of defense response to virus by host (GO:0002230) | 3.23901902 |
| 42 | regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139) | 3.23616734 |
| 43 | positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141) | 3.23616734 |
| 44 | positive regulation of humoral immune response (GO:0002922) | 3.17846487 |
| 45 | regulation of activation of Janus kinase activity (GO:0010533) | 3.13612647 |
| 46 | mast cell activation (GO:0045576) | 3.13416520 |
| 47 | tolerance induction (GO:0002507) | 3.09458732 |
| 48 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.07444237 |
| 49 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 3.05163721 |
| 50 | positive regulation of B cell mediated immunity (GO:0002714) | 3.05163721 |
| 51 | rRNA catabolic process (GO:0016075) | 3.05125275 |
| 52 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.04738620 |
| 53 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.03663072 |
| 54 | negative T cell selection (GO:0043383) | 3.03453780 |
| 55 | positive regulation of T cell mediated immunity (GO:0002711) | 3.03374468 |
| 56 | negative regulation of monooxygenase activity (GO:0032769) | 3.03364044 |
| 57 | axoneme assembly (GO:0035082) | 3.02666890 |
| 58 | positive regulation of lymphocyte mediated immunity (GO:0002708) | 2.97935892 |
| 59 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 2.96057005 |
| 60 | chaperone-mediated protein transport (GO:0072321) | 2.95527074 |
| 61 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.95192703 |
| 62 | regulation of interleukin-1 beta secretion (GO:0050706) | 2.94605285 |
| 63 | negative regulation of interleukin-17 production (GO:0032700) | 2.94187616 |
| 64 | natural killer cell activation (GO:0030101) | 2.94007744 |
| 65 | platelet dense granule organization (GO:0060155) | 2.90923142 |
| 66 | negative regulation of mast cell activation (GO:0033004) | 2.90235924 |
| 67 | positive regulation of isotype switching (GO:0045830) | 2.88491379 |
| 68 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.86703756 |
| 69 | GDP-mannose metabolic process (GO:0019673) | 2.85995954 |
| 70 | regulation of interleukin-17 production (GO:0032660) | 2.84760079 |
| 71 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class | 2.83810472 |
| 72 | ubiquinone biosynthetic process (GO:0006744) | 2.83318728 |
| 73 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.78854421 |
| 74 | regulation of growth of symbiont in host (GO:0044126) | 2.77954784 |
| 75 | negative regulation of growth of symbiont in host (GO:0044130) | 2.77954784 |
| 76 | negative regulation of growth of symbiont involved in interaction with host (GO:0044146) | 2.77954784 |
| 77 | modulation of growth of symbiont involved in interaction with host (GO:0044144) | 2.77954784 |
| 78 | negative regulation of metanephros development (GO:0072217) | 2.77769171 |
| 79 | negative thymic T cell selection (GO:0045060) | 2.77596808 |
| 80 | organelle membrane fusion (GO:0090174) | 2.77217120 |
| 81 | lymph node development (GO:0048535) | 2.76578552 |
| 82 | positive regulation of interleukin-17 production (GO:0032740) | 2.76215727 |
| 83 | negative regulation of interleukin-1 beta production (GO:0032691) | 2.76141969 |
| 84 | metallo-sulfur cluster assembly (GO:0031163) | 2.75492511 |
| 85 | iron-sulfur cluster assembly (GO:0016226) | 2.75492511 |
| 86 | positive regulation of tolerance induction (GO:0002645) | 2.75042080 |
| 87 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.74882000 |
| 88 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.74882000 |
| 89 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 2.74064718 |
| 90 | positive regulation of DNA recombination (GO:0045911) | 2.71203453 |
| 91 | ribosomal small subunit assembly (GO:0000028) | 2.70779882 |
| 92 | regulation of interleukin-12 production (GO:0032655) | 2.69851596 |
| 93 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 2.68488430 |
| 94 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 2.68096273 |
| 95 | positive regulation of T-helper 1 type immune response (GO:0002827) | 2.63853448 |
| 96 | GPI anchor metabolic process (GO:0006505) | 2.63395251 |
| 97 | chaperone mediated protein folding requiring cofactor (GO:0051085) | 2.62146039 |
| 98 | negative regulation of innate immune response (GO:0045824) | 2.60741093 |
| 99 | mast cell activation involved in immune response (GO:0002279) | 2.60361672 |
| 100 | mast cell degranulation (GO:0043303) | 2.60361672 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.89940631 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.52166145 |
| 3 | VDR_22108803_ChIP-Seq_LS180_Human | 3.15045030 |
| 4 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.92545586 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.80355351 |
| 6 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.80104524 |
| 7 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.79223119 |
| 8 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.73007258 |
| 9 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.71063943 |
| 10 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.61043074 |
| 11 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.58563645 |
| 12 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.51872977 |
| 13 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.47868141 |
| 14 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.39100288 |
| 15 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.34669626 |
| 16 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.27311375 |
| 17 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.22694559 |
| 18 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.18157752 |
| 19 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.16980665 |
| 20 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.14359227 |
| 21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.13684793 |
| 22 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.05858626 |
| 23 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.05439499 |
| 24 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 2.00295742 |
| 25 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.96296876 |
| 26 | MYB_26560356_Chip-Seq_TH2_Human | 1.93312713 |
| 27 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.84593044 |
| 28 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.82552924 |
| 29 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.81597104 |
| 30 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.71461607 |
| 31 | GATA3_26560356_Chip-Seq_TH2_Human | 1.68327492 |
| 32 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.64859028 |
| 33 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.63780148 |
| 34 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.62751617 |
| 35 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.61494949 |
| 36 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.57697146 |
| 37 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.57686347 |
| 38 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.57601153 |
| 39 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.56660777 |
| 40 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.55692049 |
| 41 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.55108955 |
| 42 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.48670152 |
| 43 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.47728095 |
| 44 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.47690936 |
| 45 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.44253315 |
| 46 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.44184997 |
| 47 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.37748486 |
| 48 | AR_20517297_ChIP-Seq_VCAP_Human | 1.35629713 |
| 49 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.35511334 |
| 50 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.35060197 |
| 51 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.34579689 |
| 52 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.29624815 |
| 53 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.27807002 |
| 54 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.24829323 |
| 55 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.24428970 |
| 56 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.24132657 |
| 57 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.24132657 |
| 58 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.23146400 |
| 59 | EWS_26573619_Chip-Seq_HEK293_Human | 1.22947886 |
| 60 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.22056054 |
| 61 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.21021833 |
| 62 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.19795988 |
| 63 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.17266868 |
| 64 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.16724516 |
| 65 | MYB_26560356_Chip-Seq_TH1_Human | 1.15813031 |
| 66 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.15234272 |
| 67 | UTX_26944678_Chip-Seq_JUKART_Human | 1.14631704 |
| 68 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.13118115 |
| 69 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.08978128 |
| 70 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.08164552 |
| 71 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.06732304 |
| 72 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.05763530 |
| 73 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.05540816 |
| 74 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.05532545 |
| 75 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.04819985 |
| 76 | GATA1_22025678_ChIP-Seq_K562_Human | 1.04404606 |
| 77 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.02327532 |
| 78 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.00707181 |
| 79 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.97057627 |
| 80 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.97057627 |
| 81 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.97023476 |
| 82 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.95860236 |
| 83 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.95401968 |
| 84 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.95153437 |
| 85 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.94369331 |
| 86 | GATA3_26560356_Chip-Seq_TH1_Human | 0.94346477 |
| 87 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.92898026 |
| 88 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.92586985 |
| 89 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.92374520 |
| 90 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.92339397 |
| 91 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.92006877 |
| 92 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.91944066 |
| 93 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.91940459 |
| 94 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.91940459 |
| 95 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.91891189 |
| 96 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.90843138 |
| 97 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.90012961 |
| 98 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.89604380 |
| 99 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.88516795 |
| 100 | NCOR_22424771_ChIP-Seq_293T_Human | 0.87499374 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.68370872 |
| 2 | MP0005377_hearing/vestibular/ear_phenot | 3.78739869 |
| 3 | MP0003878_abnormal_ear_physiology | 3.78739869 |
| 4 | MP0003436_decreased_susceptibility_to | 3.71324409 |
| 5 | MP0005257_abnormal_intraocular_pressure | 3.68117915 |
| 6 | MP0001835_abnormal_antigen_presentation | 3.17216508 |
| 7 | MP0009785_altered_susceptibility_to | 3.01839224 |
| 8 | MP0008872_abnormal_physiological_respon | 2.95436372 |
| 9 | MP0001873_stomach_inflammation | 2.89769508 |
| 10 | MP0005000_abnormal_immune_tolerance | 2.68590552 |
| 11 | MP0000372_irregular_coat_pigmentation | 2.46836952 |
| 12 | MP0009333_abnormal_splenocyte_physiolog | 2.37722050 |
| 13 | MP0008057_abnormal_DNA_replication | 2.29124270 |
| 14 | MP0000685_abnormal_immune_system | 2.01734977 |
| 15 | MP0002405_respiratory_system_inflammati | 2.00149771 |
| 16 | MP0006072_abnormal_retinal_apoptosis | 1.99439856 |
| 17 | MP0001800_abnormal_humoral_immune | 1.98047966 |
| 18 | MP0002148_abnormal_hypersensitivity_rea | 1.95921244 |
| 19 | MP0001485_abnormal_pinna_reflex | 1.92742194 |
| 20 | MP0003763_abnormal_thymus_physiology | 1.92216764 |
| 21 | MP0001790_abnormal_immune_system | 1.86797057 |
| 22 | MP0005387_immune_system_phenotype | 1.86797057 |
| 23 | MP0008875_abnormal_xenobiotic_pharmacok | 1.81761380 |
| 24 | MP0002723_abnormal_immune_serum | 1.77134024 |
| 25 | MP0001501_abnormal_sleep_pattern | 1.72523281 |
| 26 | MP0002420_abnormal_adaptive_immunity | 1.72348181 |
| 27 | MP0001819_abnormal_immune_cell | 1.71764547 |
| 28 | MP0010155_abnormal_intestine_physiology | 1.60244316 |
| 29 | MP0003646_muscle_fatigue | 1.56942406 |
| 30 | MP0001533_abnormal_skeleton_physiology | 1.56914567 |
| 31 | MP0005025_abnormal_response_to | 1.52693060 |
| 32 | MP0002933_joint_inflammation | 1.52047407 |
| 33 | MP0004742_abnormal_vestibular_system | 1.51408083 |
| 34 | MP0002452_abnormal_antigen_presenting | 1.47593686 |
| 35 | MP0002006_tumorigenesis | 1.44158184 |
| 36 | MP0001346_abnormal_lacrimal_gland | 1.42974424 |
| 37 | MP0004885_abnormal_endolymph | 1.41795909 |
| 38 | MP0008877_abnormal_DNA_methylation | 1.40210120 |
| 39 | MP0002102_abnormal_ear_morphology | 1.40154162 |
| 40 | MP0003195_calcinosis | 1.39088131 |
| 41 | MP0000703_abnormal_thymus_morphology | 1.37500348 |
| 42 | MP0005310_abnormal_salivary_gland | 1.35467126 |
| 43 | MP0005645_abnormal_hypothalamus_physiol | 1.33696014 |
| 44 | MP0001845_abnormal_inflammatory_respons | 1.30062856 |
| 45 | MP0002419_abnormal_innate_immunity | 1.29730258 |
| 46 | MP0002722_abnormal_immune_system | 1.27958949 |
| 47 | MP0006036_abnormal_mitochondrial_physio | 1.26405707 |
| 48 | MP0000716_abnormal_immune_system | 1.25326985 |
| 49 | MP0009764_decreased_sensitivity_to | 1.23131347 |
| 50 | MP0005646_abnormal_pituitary_gland | 1.20206274 |
| 51 | MP0004782_abnormal_surfactant_physiolog | 1.15938025 |
| 52 | MP0001905_abnormal_dopamine_level | 1.15519784 |
| 53 | MP0006035_abnormal_mitochondrial_morpho | 1.12005800 |
| 54 | MP0003866_abnormal_defecation | 1.11468168 |
| 55 | MP0008058_abnormal_DNA_repair | 1.10826914 |
| 56 | MP0000689_abnormal_spleen_morphology | 1.10637415 |
| 57 | MP0005551_abnormal_eye_electrophysiolog | 1.07959994 |
| 58 | MP0002163_abnormal_gland_morphology | 1.07547999 |
| 59 | MP0002398_abnormal_bone_marrow | 1.05846706 |
| 60 | MP0001881_abnormal_mammary_gland | 1.04523250 |
| 61 | MP0001919_abnormal_reproductive_system | 1.04437985 |
| 62 | MP0001984_abnormal_olfaction | 1.03857677 |
| 63 | MP0008469_abnormal_protein_level | 1.02093608 |
| 64 | MP0003806_abnormal_nucleotide_metabolis | 0.98263547 |
| 65 | MP0005085_abnormal_gallbladder_physiolo | 0.97970674 |
| 66 | MP0001853_heart_inflammation | 0.96501537 |
| 67 | MP0003724_increased_susceptibility_to | 0.94711162 |
| 68 | MP0005389_reproductive_system_phenotype | 0.93958193 |
| 69 | MP0002429_abnormal_blood_cell | 0.92940708 |
| 70 | MP0001663_abnormal_digestive_system | 0.91716920 |
| 71 | MP0005365_abnormal_bile_salt | 0.88828416 |
| 72 | MP0005253_abnormal_eye_physiology | 0.88774347 |
| 73 | MP0003786_premature_aging | 0.86772807 |
| 74 | MP0005636_abnormal_mineral_homeostasis | 0.84571386 |
| 75 | MP0000569_abnormal_digit_pigmentation | 0.83950206 |
| 76 | MP0000383_abnormal_hair_follicle | 0.83559194 |
| 77 | MP0005075_abnormal_melanosome_morpholog | 0.81075649 |
| 78 | MP0005360_urolithiasis | 0.78883437 |
| 79 | MP0005390_skeleton_phenotype | 0.78651412 |
| 80 | MP0006292_abnormal_olfactory_placode | 0.78199632 |
| 81 | MP0002693_abnormal_pancreas_physiology | 0.75732578 |
| 82 | MP0004142_abnormal_muscle_tone | 0.75617993 |
| 83 | MP0002876_abnormal_thyroid_physiology | 0.74961202 |
| 84 | MP0002160_abnormal_reproductive_system | 0.74145173 |
| 85 | MP0003137_abnormal_impulse_conducting | 0.73691551 |
| 86 | MP0001661_extended_life_span | 0.73448154 |
| 87 | MP0005379_endocrine/exocrine_gland_phen | 0.73116197 |
| 88 | MP0002138_abnormal_hepatobiliary_system | 0.71819131 |
| 89 | MP0002234_abnormal_pharynx_morphology | 0.71055078 |
| 90 | MP0005670_abnormal_white_adipose | 0.70129741 |
| 91 | MP0002166_altered_tumor_susceptibility | 0.69731263 |
| 92 | MP0002019_abnormal_tumor_incidence | 0.69654761 |
| 93 | MP0000465_gastrointestinal_hemorrhage | 0.69362584 |
| 94 | MP0003879_abnormal_hair_cell | 0.68871514 |
| 95 | MP0001765_abnormal_ion_homeostasis | 0.68437929 |
| 96 | MP0009697_abnormal_copulation | 0.68349874 |
| 97 | MP0006054_spinal_hemorrhage | 0.67229284 |
| 98 | MP0004957_abnormal_blastocyst_morpholog | 0.66867863 |
| 99 | MP0002751_abnormal_autonomic_nervous | 0.66018943 |
| 100 | MP0003448_altered_tumor_morphology | 0.65973022 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Stomach cancer (HP:0012126) | 6.74777854 |
| 2 | Abnormality of B cell number (HP:0010975) | 6.74006823 |
| 3 | Abnormality of T cell number (HP:0011839) | 4.27913962 |
| 4 | Increased IgM level (HP:0003496) | 4.27041431 |
| 5 | IgG deficiency (HP:0004315) | 4.21431429 |
| 6 | B lymphocytopenia (HP:0010976) | 4.19154269 |
| 7 | Congenital stationary night blindness (HP:0007642) | 4.11107155 |
| 8 | Reduced antithrombin III activity (HP:0001976) | 3.78936865 |
| 9 | Eosinophilia (HP:0001880) | 3.68723960 |
| 10 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.63519600 |
| 11 | Abnormality of eosinophils (HP:0001879) | 3.60483404 |
| 12 | Autoimmune thrombocytopenia (HP:0001973) | 3.55385955 |
| 13 | Methylmalonic acidemia (HP:0002912) | 3.40321408 |
| 14 | Optic neuritis (HP:0100653) | 3.30873341 |
| 15 | Retrobulbar optic neuritis (HP:0100654) | 3.30873341 |
| 16 | T lymphocytopenia (HP:0005403) | 3.28700739 |
| 17 | Methylmalonic aciduria (HP:0012120) | 3.14899945 |
| 18 | Increased intramyocellular lipid droplets (HP:0012240) | 3.09098665 |
| 19 | Autoimmune hemolytic anemia (HP:0001890) | 3.03600462 |
| 20 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.01656404 |
| 21 | Mitochondrial inheritance (HP:0001427) | 3.01502445 |
| 22 | Abnormality of T cells (HP:0002843) | 2.94610894 |
| 23 | Congenital, generalized hypertrichosis (HP:0004540) | 2.91667864 |
| 24 | Granulocytopenia (HP:0001913) | 2.82391474 |
| 25 | Type I transferrin isoform profile (HP:0003642) | 2.76076622 |
| 26 | Acute necrotizing encephalopathy (HP:0006965) | 2.74713889 |
| 27 | Absent/shortened dynein arms (HP:0200106) | 2.73037942 |
| 28 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.73037942 |
| 29 | Orchitis (HP:0100796) | 2.70305988 |
| 30 | Increased hepatocellular lipid droplets (HP:0006565) | 2.69869315 |
| 31 | Leukocytosis (HP:0001974) | 2.66609590 |
| 32 | Increased CSF lactate (HP:0002490) | 2.66188797 |
| 33 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.60859227 |
| 34 | Stomatitis (HP:0010280) | 2.60307352 |
| 35 | Attenuation of retinal blood vessels (HP:0007843) | 2.58460289 |
| 36 | Increased muscle lipid content (HP:0009058) | 2.57843292 |
| 37 | Renal cortical cysts (HP:0000803) | 2.57610656 |
| 38 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.54487825 |
| 39 | Abnormality of the renal cortex (HP:0011035) | 2.54411002 |
| 40 | Myositis (HP:0100614) | 2.53836378 |
| 41 | Abnormality of T cell physiology (HP:0011840) | 2.53835373 |
| 42 | Keratoconjunctivitis (HP:0001096) | 2.48921290 |
| 43 | Colon cancer (HP:0003003) | 2.47745948 |
| 44 | Abnormality of the pons (HP:0007361) | 2.47731772 |
| 45 | Hepatocellular necrosis (HP:0001404) | 2.45107456 |
| 46 | Abnormal ciliary motility (HP:0012262) | 2.40222877 |
| 47 | Hyperglycinemia (HP:0002154) | 2.39894755 |
| 48 | Carpal bone hypoplasia (HP:0001498) | 2.34974544 |
| 49 | Lipid accumulation in hepatocytes (HP:0006561) | 2.34907610 |
| 50 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.34373456 |
| 51 | Hypoplasia of the pons (HP:0012110) | 2.25367666 |
| 52 | Metabolic alkalosis (HP:0200114) | 2.24726772 |
| 53 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.23135520 |
| 54 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.23135520 |
| 55 | Progressive macrocephaly (HP:0004481) | 2.17634724 |
| 56 | Severe combined immunodeficiency (HP:0004430) | 2.17297580 |
| 57 | Hypokalemic alkalosis (HP:0001949) | 2.17226355 |
| 58 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.16143126 |
| 59 | 3-Methylglutaconic aciduria (HP:0003535) | 2.15427915 |
| 60 | Exertional dyspnea (HP:0002875) | 2.09520117 |
| 61 | Keratoconjunctivitis sicca (HP:0001097) | 2.08731113 |
| 62 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.08429697 |
| 63 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.07721346 |
| 64 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.07721346 |
| 65 | Abnormal protein glycosylation (HP:0012346) | 2.07721346 |
| 66 | Abnormal glycosylation (HP:0012345) | 2.07721346 |
| 67 | Arthropathy (HP:0003040) | 2.07020493 |
| 68 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.04674081 |
| 69 | Hyperphosphaturia (HP:0003109) | 2.04087892 |
| 70 | Hepatic necrosis (HP:0002605) | 2.03446492 |
| 71 | Abolished electroretinogram (ERG) (HP:0000550) | 2.01510951 |
| 72 | Acute encephalopathy (HP:0006846) | 2.00643421 |
| 73 | Neutropenia (HP:0001875) | 1.98136339 |
| 74 | Hypoproteinemia (HP:0003075) | 1.97292320 |
| 75 | Abnormality of vitamin B metabolism (HP:0004340) | 1.95680785 |
| 76 | Pancreatic cysts (HP:0001737) | 1.94130662 |
| 77 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.92813085 |
| 78 | Encephalitis (HP:0002383) | 1.91931796 |
| 79 | Constricted visual fields (HP:0001133) | 1.91915563 |
| 80 | Anhidrosis (HP:0000970) | 1.91618654 |
| 81 | Ketosis (HP:0001946) | 1.90141396 |
| 82 | Lactic acidosis (HP:0003128) | 1.90011490 |
| 83 | Chronic diarrhea (HP:0002028) | 1.89569199 |
| 84 | Thyroiditis (HP:0100646) | 1.87998196 |
| 85 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.87960066 |
| 86 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.87903031 |
| 87 | Increased serum lactate (HP:0002151) | 1.85839121 |
| 88 | Pendular nystagmus (HP:0012043) | 1.84050813 |
| 89 | Cerebral edema (HP:0002181) | 1.83371558 |
| 90 | Pulmonary infiltrates (HP:0002113) | 1.83287906 |
| 91 | Renal salt wasting (HP:0000127) | 1.81558352 |
| 92 | Abnormality of chloride homeostasis (HP:0011422) | 1.80579106 |
| 93 | IgA deficiency (HP:0002720) | 1.80513289 |
| 94 | Recurrent bronchitis (HP:0002837) | 1.80262165 |
| 95 | Hypomagnesemia (HP:0002917) | 1.78797724 |
| 96 | Respiratory failure (HP:0002878) | 1.77745123 |
| 97 | Keratitis (HP:0000491) | 1.77333898 |
| 98 | Hypoalbuminemia (HP:0003073) | 1.75210915 |
| 99 | Abnormal albumin level (HP:0012116) | 1.75210915 |
| 100 | Medial flaring of the eyebrow (HP:0010747) | 1.75131315 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | PINK1 | 4.52338914 |
| 2 | GRK6 | 4.47798833 |
| 3 | BCKDK | 4.12815273 |
| 4 | MAP4K2 | 4.03810256 |
| 5 | TXK | 3.97856715 |
| 6 | TSSK6 | 3.59238761 |
| 7 | PASK | 2.72446098 |
| 8 | ZAK | 2.64934161 |
| 9 | CAMKK2 | 2.22955293 |
| 10 | KDR | 2.10978344 |
| 11 | ADRBK2 | 2.07388811 |
| 12 | VRK2 | 2.00993486 |
| 13 | TAOK3 | 1.89938659 |
| 14 | EIF2AK1 | 1.83263224 |
| 15 | ERBB3 | 1.81594480 |
| 16 | NME1 | 1.78533360 |
| 17 | TESK2 | 1.75335445 |
| 18 | GRK1 | 1.72073957 |
| 19 | TLK1 | 1.69799837 |
| 20 | MST4 | 1.62532861 |
| 21 | CAMKK1 | 1.61864988 |
| 22 | MAP3K9 | 1.52010368 |
| 23 | NUAK1 | 1.48939306 |
| 24 | EIF2AK3 | 1.43587873 |
| 25 | IKBKE | 1.29753510 |
| 26 | NME2 | 1.25946438 |
| 27 | MATK | 1.22699823 |
| 28 | MAP2K2 | 1.18862199 |
| 29 | IKBKB | 1.11463449 |
| 30 | ITK | 1.09407681 |
| 31 | JAK1 | 1.08833802 |
| 32 | ARAF | 1.08648260 |
| 33 | IRAK4 | 1.07620601 |
| 34 | SRPK1 | 1.04195468 |
| 35 | VRK1 | 1.03383009 |
| 36 | ALK | 0.98033110 |
| 37 | MAP3K14 | 0.95825028 |
| 38 | MAP3K12 | 0.95340297 |
| 39 | BMPR2 | 0.93741010 |
| 40 | JAK3 | 0.92882064 |
| 41 | FRK | 0.91901836 |
| 42 | LCK | 0.89078550 |
| 43 | BTK | 0.88818447 |
| 44 | NEK6 | 0.86052731 |
| 45 | PRKCQ | 0.83804963 |
| 46 | PIM1 | 0.82002620 |
| 47 | CSNK1G3 | 0.80266590 |
| 48 | CSNK1G1 | 0.80176883 |
| 49 | MAP2K6 | 0.80064667 |
| 50 | NTRK1 | 0.79758652 |
| 51 | TBK1 | 0.72480765 |
| 52 | MAP4K1 | 0.72261038 |
| 53 | INSRR | 0.71801048 |
| 54 | CSNK1A1L | 0.71631268 |
| 55 | RAF1 | 0.67871126 |
| 56 | MAP3K11 | 0.67174365 |
| 57 | PLK3 | 0.66476000 |
| 58 | TRPM7 | 0.64906899 |
| 59 | SYK | 0.64807333 |
| 60 | STK24 | 0.62385972 |
| 61 | MAP3K5 | 0.61762172 |
| 62 | FLT3 | 0.61478956 |
| 63 | TEC | 0.58435497 |
| 64 | MYLK | 0.54177229 |
| 65 | IGF1R | 0.53864510 |
| 66 | CDK19 | 0.52309515 |
| 67 | TAOK1 | 0.52101136 |
| 68 | TAOK2 | 0.52080635 |
| 69 | KIT | 0.50618336 |
| 70 | CSNK1G2 | 0.46372556 |
| 71 | LYN | 0.46195746 |
| 72 | CDK4 | 0.43878536 |
| 73 | TNK2 | 0.43737824 |
| 74 | EIF2AK2 | 0.41843010 |
| 75 | AKT2 | 0.37982987 |
| 76 | OXSR1 | 0.37609977 |
| 77 | LIMK1 | 0.35752335 |
| 78 | MAP3K8 | 0.35485172 |
| 79 | CAMK1 | 0.34545755 |
| 80 | TIE1 | 0.33093420 |
| 81 | GRK7 | 0.32716369 |
| 82 | TESK1 | 0.32033533 |
| 83 | PIK3CA | 0.31601321 |
| 84 | PLK2 | 0.29933855 |
| 85 | HCK | 0.29369917 |
| 86 | WNK3 | 0.28008036 |
| 87 | MARK3 | 0.27994057 |
| 88 | PDK2 | 0.27238325 |
| 89 | PRKD2 | 0.27052322 |
| 90 | ZAP70 | 0.27036592 |
| 91 | RPS6KA5 | 0.26734527 |
| 92 | OBSCN | 0.26404966 |
| 93 | ABL2 | 0.25728016 |
| 94 | TYK2 | 0.25518133 |
| 95 | EGFR | 0.25391309 |
| 96 | MAPK15 | 0.24376190 |
| 97 | PKN1 | 0.21697624 |
| 98 | CSNK2A1 | 0.21642772 |
| 99 | ADRBK1 | 0.21121147 |
| 100 | PRKCA | 0.20153371 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.04182527 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.54142087 |
| 3 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 3.26875107 |
| 4 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.84169556 |
| 5 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.78169945 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.75598796 |
| 7 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.32393079 |
| 8 | Allograft rejection_Homo sapiens_hsa05330 | 2.21629175 |
| 9 | Ribosome_Homo sapiens_hsa03010 | 2.21145911 |
| 10 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.14339080 |
| 11 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.13566766 |
| 12 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.01665415 |
| 13 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.01276050 |
| 14 | Parkinsons disease_Homo sapiens_hsa05012 | 1.82570498 |
| 15 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.81815570 |
| 16 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.76303249 |
| 17 | Protein export_Homo sapiens_hsa03060 | 1.73710427 |
| 18 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.62880224 |
| 19 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.61654964 |
| 20 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.57466505 |
| 21 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.55363086 |
| 22 | Basal transcription factors_Homo sapiens_hsa03022 | 1.52718195 |
| 23 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.48771684 |
| 24 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.44850464 |
| 25 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.43951452 |
| 26 | Huntingtons disease_Homo sapiens_hsa05016 | 1.43662840 |
| 27 | RNA degradation_Homo sapiens_hsa03018 | 1.38548565 |
| 28 | Base excision repair_Homo sapiens_hsa03410 | 1.33279112 |
| 29 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.30662834 |
| 30 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.29026760 |
| 31 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.27928048 |
| 32 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.24602393 |
| 33 | Malaria_Homo sapiens_hsa05144 | 1.24533537 |
| 34 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.22737935 |
| 35 | Alzheimers disease_Homo sapiens_hsa05010 | 1.22456488 |
| 36 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.22147008 |
| 37 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.17423264 |
| 38 | Spliceosome_Homo sapiens_hsa03040 | 1.17063367 |
| 39 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.16840972 |
| 40 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.16455779 |
| 41 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.16323978 |
| 42 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.14826355 |
| 43 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.11690846 |
| 44 | Measles_Homo sapiens_hsa05162 | 1.10048132 |
| 45 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.08719513 |
| 46 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.07860691 |
| 47 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.07282368 |
| 48 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.00533629 |
| 49 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.98638531 |
| 50 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.98033094 |
| 51 | Retinol metabolism_Homo sapiens_hsa00830 | 0.93731994 |
| 52 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.90587410 |
| 53 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.86685254 |
| 54 | Phototransduction_Homo sapiens_hsa04744 | 0.86638841 |
| 55 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.85876635 |
| 56 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.84146611 |
| 57 | Purine metabolism_Homo sapiens_hsa00230 | 0.83188077 |
| 58 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.81080066 |
| 59 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.80819223 |
| 60 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.80467844 |
| 61 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.78349846 |
| 62 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.77802282 |
| 63 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.76250587 |
| 64 | Asthma_Homo sapiens_hsa05310 | 0.76075065 |
| 65 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.71748483 |
| 66 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.71102915 |
| 67 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.70638926 |
| 68 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.69571947 |
| 69 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.68908276 |
| 70 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.67260296 |
| 71 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.66727937 |
| 72 | ABC transporters_Homo sapiens_hsa02010 | 0.65136247 |
| 73 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.65125185 |
| 74 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.61345060 |
| 75 | Peroxisome_Homo sapiens_hsa04146 | 0.61216452 |
| 76 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.60224717 |
| 77 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.58010263 |
| 78 | Viral myocarditis_Homo sapiens_hsa05416 | 0.57235918 |
| 79 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.55437280 |
| 80 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.54025306 |
| 81 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.52218254 |
| 82 | Nicotine addiction_Homo sapiens_hsa05033 | 0.50653574 |
| 83 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.49885551 |
| 84 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.49220670 |
| 85 | Apoptosis_Homo sapiens_hsa04210 | 0.48456631 |
| 86 | Metabolic pathways_Homo sapiens_hsa01100 | 0.48345905 |
| 87 | RNA transport_Homo sapiens_hsa03013 | 0.44414320 |
| 88 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.38115093 |
| 89 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.38112639 |
| 90 | Salivary secretion_Homo sapiens_hsa04970 | 0.37125807 |
| 91 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.35919240 |
| 92 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.35880781 |
| 93 | Homologous recombination_Homo sapiens_hsa03440 | 0.33071032 |
| 94 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.32617238 |
| 95 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.32375521 |
| 96 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.30373501 |
| 97 | Shigellosis_Homo sapiens_hsa05131 | 0.28005283 |
| 98 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.27129398 |
| 99 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.26970130 |
| 100 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.25289624 |

