

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 4.53481500 |
| 2 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 4.43565055 |
| 3 | regulation of mitotic spindle checkpoint (GO:1903504) | 4.43565055 |
| 4 | proteasome assembly (GO:0043248) | 4.33789531 |
| 5 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.00789779 |
| 6 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.92903358 |
| 7 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.74256708 |
| 8 | ATP synthesis coupled proton transport (GO:0015986) | 3.67120119 |
| 9 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.67120119 |
| 10 | kinetochore assembly (GO:0051382) | 3.64463179 |
| 11 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.61899950 |
| 12 | protein neddylation (GO:0045116) | 3.54061919 |
| 13 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.49004582 |
| 14 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.49004582 |
| 15 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.47915252 |
| 16 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.45401857 |
| 17 | pseudouridine synthesis (GO:0001522) | 3.44535016 |
| 18 | chromatin remodeling at centromere (GO:0031055) | 3.41724768 |
| 19 | ribosomal small subunit assembly (GO:0000028) | 3.41048012 |
| 20 | regulation of immunoglobulin secretion (GO:0051023) | 3.38812750 |
| 21 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.30522588 |
| 22 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.30522588 |
| 23 | rRNA modification (GO:0000154) | 3.28655583 |
| 24 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.28116651 |
| 25 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.28116651 |
| 26 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.27233206 |
| 27 | maturation of SSU-rRNA (GO:0030490) | 3.26946816 |
| 28 | CENP-A containing nucleosome assembly (GO:0034080) | 3.26817770 |
| 29 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.25867070 |
| 30 | kinetochore organization (GO:0051383) | 3.21146105 |
| 31 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.20113218 |
| 32 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.19299088 |
| 33 | tRNA processing (GO:0008033) | 3.16726773 |
| 34 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.15640908 |
| 35 | NADH dehydrogenase complex assembly (GO:0010257) | 3.15640908 |
| 36 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.15640908 |
| 37 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.15474409 |
| 38 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.15474409 |
| 39 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.15474409 |
| 40 | mitochondrial RNA metabolic process (GO:0000959) | 3.15087438 |
| 41 | piRNA metabolic process (GO:0034587) | 3.15086899 |
| 42 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.13884364 |
| 43 | termination of RNA polymerase III transcription (GO:0006386) | 3.13884364 |
| 44 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.13408826 |
| 45 | DNA double-strand break processing (GO:0000729) | 3.12252218 |
| 46 | histone exchange (GO:0043486) | 3.10701215 |
| 47 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.10406489 |
| 48 | DNA damage response, detection of DNA damage (GO:0042769) | 3.09733680 |
| 49 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.09235280 |
| 50 | DNA ligation (GO:0006266) | 3.07672553 |
| 51 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.05191906 |
| 52 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.05012647 |
| 53 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.05012647 |
| 54 | cullin deneddylation (GO:0010388) | 3.04495815 |
| 55 | protein complex biogenesis (GO:0070271) | 3.03277234 |
| 56 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.02337210 |
| 57 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.02337210 |
| 58 | isotype switching (GO:0045190) | 3.02337210 |
| 59 | maturation of 5.8S rRNA (GO:0000460) | 3.01529136 |
| 60 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.01262906 |
| 61 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.01262906 |
| 62 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.99468924 |
| 63 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.99065700 |
| 64 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.96803161 |
| 65 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.95869101 |
| 66 | chaperone-mediated protein transport (GO:0072321) | 2.92570951 |
| 67 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.92099839 |
| 68 | IMP biosynthetic process (GO:0006188) | 2.91774981 |
| 69 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.91148994 |
| 70 | ribosome assembly (GO:0042255) | 2.90188290 |
| 71 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.89929983 |
| 72 | negative regulation of ligase activity (GO:0051352) | 2.89929983 |
| 73 | tRNA metabolic process (GO:0006399) | 2.89777863 |
| 74 | synapsis (GO:0007129) | 2.88242741 |
| 75 | rRNA processing (GO:0006364) | 2.88223322 |
| 76 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.87462041 |
| 77 | rRNA methylation (GO:0031167) | 2.86850814 |
| 78 | rRNA metabolic process (GO:0016072) | 2.84972992 |
| 79 | nucleobase biosynthetic process (GO:0046112) | 2.83606271 |
| 80 | protein deneddylation (GO:0000338) | 2.80382348 |
| 81 | mismatch repair (GO:0006298) | 2.78210931 |
| 82 | respiratory chain complex IV assembly (GO:0008535) | 2.78200972 |
| 83 | tRNA modification (GO:0006400) | 2.76806143 |
| 84 | ribosomal large subunit biogenesis (GO:0042273) | 2.75652856 |
| 85 | L-methionine salvage (GO:0071267) | 2.73970054 |
| 86 | L-methionine biosynthetic process (GO:0071265) | 2.73970054 |
| 87 | amino acid salvage (GO:0043102) | 2.73970054 |
| 88 | purine nucleobase biosynthetic process (GO:0009113) | 2.73246312 |
| 89 | male meiosis (GO:0007140) | 2.72902918 |
| 90 | adenosine metabolic process (GO:0046085) | 2.71361897 |
| 91 | ncRNA metabolic process (GO:0034660) | 2.70403547 |
| 92 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.68720726 |
| 93 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.67707172 |
| 94 | organelle disassembly (GO:1903008) | 2.66673748 |
| 95 | ncRNA processing (GO:0034470) | 2.65376239 |
| 96 | transcription from mitochondrial promoter (GO:0006390) | 2.64947573 |
| 97 | regulation of chronic inflammatory response (GO:0002676) | 2.63402845 |
| 98 | somatic diversification of immune receptors via germline recombination within a single locus (GO:000 | 2.62756779 |
| 99 | somatic cell DNA recombination (GO:0016444) | 2.62756779 |
| 100 | somatic diversification of immune receptors (GO:0002200) | 2.62119043 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.10929916 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.25161345 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.63569541 |
| 4 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.22425771 |
| 5 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.16613115 |
| 6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.07909873 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.05381957 |
| 8 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.76569832 |
| 9 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.74197252 |
| 10 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.59688562 |
| 11 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.58054046 |
| 12 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.57010907 |
| 13 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.54098654 |
| 14 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.53754865 |
| 15 | VDR_22108803_ChIP-Seq_LS180_Human | 2.45358223 |
| 16 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.44041273 |
| 17 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.40620252 |
| 18 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.36570896 |
| 19 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.28195560 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.22796237 |
| 21 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.15816488 |
| 22 | EWS_26573619_Chip-Seq_HEK293_Human | 2.04041684 |
| 23 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.98836125 |
| 24 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.95702385 |
| 25 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.95578915 |
| 26 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.94716437 |
| 27 | FUS_26573619_Chip-Seq_HEK293_Human | 1.88860226 |
| 28 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.88394317 |
| 29 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.82811100 |
| 30 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.82665400 |
| 31 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.81146914 |
| 32 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.80244179 |
| 33 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.75081993 |
| 34 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.71893947 |
| 35 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.68057081 |
| 36 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.64845595 |
| 37 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.63230584 |
| 38 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.61416044 |
| 39 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.56816701 |
| 40 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.55414293 |
| 41 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.47405772 |
| 42 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.46276222 |
| 43 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.46060437 |
| 44 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.44085598 |
| 45 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.43703217 |
| 46 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.39504661 |
| 47 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.37305173 |
| 48 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.35033005 |
| 49 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.31791008 |
| 50 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.28154999 |
| 51 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.27927206 |
| 52 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.26999864 |
| 53 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.26999864 |
| 54 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.25525339 |
| 55 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.25027595 |
| 56 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.24061256 |
| 57 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.23742678 |
| 58 | P300_19829295_ChIP-Seq_ESCs_Human | 1.23645229 |
| 59 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.23637666 |
| 60 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.21473614 |
| 61 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.21323992 |
| 62 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.18896332 |
| 63 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.18202041 |
| 64 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.16962479 |
| 65 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.13581760 |
| 66 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.13491565 |
| 67 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.13135190 |
| 68 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.13099772 |
| 69 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.11501650 |
| 70 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.11501650 |
| 71 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.11433348 |
| 72 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.10938736 |
| 73 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.07467634 |
| 74 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.06029377 |
| 75 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.05211868 |
| 76 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.05208042 |
| 77 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.05062327 |
| 78 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.04477896 |
| 79 | AR_20517297_ChIP-Seq_VCAP_Human | 1.03667857 |
| 80 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.00576447 |
| 81 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.98814867 |
| 82 | NCOR_22424771_ChIP-Seq_293T_Human | 0.97815467 |
| 83 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.96165738 |
| 84 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.95645223 |
| 85 | AR_21909140_ChIP-Seq_LNCAP_Human | 0.95351068 |
| 86 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.95150349 |
| 87 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.94030119 |
| 88 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.93991843 |
| 89 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.92734168 |
| 90 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.91882137 |
| 91 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.91882137 |
| 92 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.91346707 |
| 93 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.91321250 |
| 94 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.89973978 |
| 95 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.89420348 |
| 96 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.88987266 |
| 97 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.87278517 |
| 98 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.86952461 |
| 99 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.86418885 |
| 100 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.85129642 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000372_irregular_coat_pigmentation | 3.82311685 |
| 2 | MP0006292_abnormal_olfactory_placode | 3.48865776 |
| 3 | MP0002102_abnormal_ear_morphology | 3.24025731 |
| 4 | MP0008877_abnormal_DNA_methylation | 3.05171714 |
| 5 | MP0003718_maternal_effect | 2.62453765 |
| 6 | MP0003806_abnormal_nucleotide_metabolis | 2.61257575 |
| 7 | MP0008058_abnormal_DNA_repair | 2.58168490 |
| 8 | MP0006072_abnormal_retinal_apoptosis | 2.54226682 |
| 9 | MP0001293_anophthalmia | 2.49076235 |
| 10 | MP0000566_synostosis | 2.47012634 |
| 11 | MP0010094_abnormal_chromosome_stability | 2.39964154 |
| 12 | MP0003693_abnormal_embryo_hatching | 2.35556906 |
| 13 | MP0005377_hearing/vestibular/ear_phenot | 2.32427720 |
| 14 | MP0003878_abnormal_ear_physiology | 2.32427720 |
| 15 | MP0005075_abnormal_melanosome_morpholog | 2.16678892 |
| 16 | MP0002938_white_spotting | 2.07932733 |
| 17 | MP0005408_hypopigmentation | 1.95994174 |
| 18 | MP0003567_abnormal_fetal_cardiomyocyte | 1.88482160 |
| 19 | MP0003786_premature_aging | 1.86709065 |
| 20 | MP0004957_abnormal_blastocyst_morpholog | 1.83687262 |
| 21 | MP0005084_abnormal_gallbladder_morpholo | 1.73340135 |
| 22 | MP0001348_abnormal_lacrimal_gland | 1.72540958 |
| 23 | MP0005253_abnormal_eye_physiology | 1.71587411 |
| 24 | MP0003111_abnormal_nucleus_morphology | 1.65529799 |
| 25 | MP0008872_abnormal_physiological_respon | 1.64135990 |
| 26 | MP0002736_abnormal_nociception_after | 1.63652561 |
| 27 | MP0005671_abnormal_response_to | 1.62488323 |
| 28 | MP0008875_abnormal_xenobiotic_pharmacok | 1.54721864 |
| 29 | MP0004147_increased_porphyrin_level | 1.51711457 |
| 30 | MP0004885_abnormal_endolymph | 1.39670437 |
| 31 | MP0001968_abnormal_touch/_nociception | 1.36420327 |
| 32 | MP0002234_abnormal_pharynx_morphology | 1.36183799 |
| 33 | MP0001529_abnormal_vocalization | 1.36165474 |
| 34 | MP0001835_abnormal_antigen_presentation | 1.33009709 |
| 35 | MP0005551_abnormal_eye_electrophysiolog | 1.32884805 |
| 36 | MP0003195_calcinosis | 1.31717936 |
| 37 | MP0003136_yellow_coat_color | 1.31228356 |
| 38 | MP0000537_abnormal_urethra_morphology | 1.26385924 |
| 39 | MP0008007_abnormal_cellular_replicative | 1.20645583 |
| 40 | MP0002095_abnormal_skin_pigmentation | 1.19148327 |
| 41 | MP0008995_early_reproductive_senescence | 1.18126794 |
| 42 | MP0000631_abnormal_neuroendocrine_gland | 1.16199036 |
| 43 | MP0006036_abnormal_mitochondrial_physio | 1.16143805 |
| 44 | MP0002837_dystrophic_cardiac_calcinosis | 1.14416196 |
| 45 | MP0000647_abnormal_sebaceous_gland | 1.11772009 |
| 46 | MP0003077_abnormal_cell_cycle | 1.10771969 |
| 47 | MP0003186_abnormal_redox_activity | 1.09939172 |
| 48 | MP0001485_abnormal_pinna_reflex | 1.08721834 |
| 49 | MP0001984_abnormal_olfaction | 1.07162191 |
| 50 | MP0005646_abnormal_pituitary_gland | 1.06893861 |
| 51 | MP0003121_genomic_imprinting | 1.06481112 |
| 52 | MP0001764_abnormal_homeostasis | 1.03113292 |
| 53 | MP0002282_abnormal_trachea_morphology | 1.02890139 |
| 54 | MP0002751_abnormal_autonomic_nervous | 1.02345640 |
| 55 | MP0001929_abnormal_gametogenesis | 1.01925383 |
| 56 | MP0003646_muscle_fatigue | 0.98533855 |
| 57 | MP0008789_abnormal_olfactory_epithelium | 0.97403486 |
| 58 | MP0005391_vision/eye_phenotype | 0.97361003 |
| 59 | MP0002210_abnormal_sex_determination | 0.97324294 |
| 60 | MP0001853_heart_inflammation | 0.96472366 |
| 61 | MP0000569_abnormal_digit_pigmentation | 0.95946931 |
| 62 | MP0003011_delayed_dark_adaptation | 0.95593479 |
| 63 | MP0002272_abnormal_nervous_system | 0.95532624 |
| 64 | MP0002006_tumorigenesis | 0.94497021 |
| 65 | MP0003937_abnormal_limbs/digits/tail_de | 0.94363144 |
| 66 | MP0002138_abnormal_hepatobiliary_system | 0.94036124 |
| 67 | MP0008932_abnormal_embryonic_tissue | 0.93438892 |
| 68 | MP0009046_muscle_twitch | 0.89681174 |
| 69 | MP0003787_abnormal_imprinting | 0.88373033 |
| 70 | MP0004043_abnormal_pH_regulation | 0.86982690 |
| 71 | MP0006035_abnormal_mitochondrial_morpho | 0.84222869 |
| 72 | MP0000049_abnormal_middle_ear | 0.83313169 |
| 73 | MP0004142_abnormal_muscle_tone | 0.83233598 |
| 74 | MP0001119_abnormal_female_reproductive | 0.82601382 |
| 75 | MP0001145_abnormal_male_reproductive | 0.82080858 |
| 76 | MP0000653_abnormal_sex_gland | 0.81683413 |
| 77 | MP0001986_abnormal_taste_sensitivity | 0.81055158 |
| 78 | MP0005174_abnormal_tail_pigmentation | 0.79655104 |
| 79 | MP0003119_abnormal_digestive_system | 0.79353486 |
| 80 | MP0005389_reproductive_system_phenotype | 0.78969307 |
| 81 | MP0008775_abnormal_heart_ventricle | 0.77257687 |
| 82 | MP0009697_abnormal_copulation | 0.76733361 |
| 83 | MP0001919_abnormal_reproductive_system | 0.74078659 |
| 84 | MP0004133_heterotaxia | 0.73701719 |
| 85 | MP0001324_abnormal_eye_pigmentation | 0.72196615 |
| 86 | MP0005167_abnormal_blood-brain_barrier | 0.70758891 |
| 87 | MP0010030_abnormal_orbit_morphology | 0.70617678 |
| 88 | MP0003880_abnormal_central_pattern | 0.69777748 |
| 89 | MP0001286_abnormal_eye_development | 0.68592324 |
| 90 | MP0000427_abnormal_hair_cycle | 0.68378995 |
| 91 | MP0003698_abnormal_male_reproductive | 0.68364605 |
| 92 | MP0005645_abnormal_hypothalamus_physiol | 0.67706135 |
| 93 | MP0002111_abnormal_tail_morphology | 0.67207688 |
| 94 | MP0000490_abnormal_crypts_of | 0.67119921 |
| 95 | MP0003283_abnormal_digestive_organ | 0.66834415 |
| 96 | MP0004924_abnormal_behavior | 0.65691627 |
| 97 | MP0005386_behavior/neurological_phenoty | 0.65691627 |
| 98 | MP0004134_abnormal_chest_morphology | 0.65350658 |
| 99 | MP0002822_catalepsy | 0.64715639 |
| 100 | MP0001873_stomach_inflammation | 0.62946839 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of the labia minora (HP:0012880) | 3.70330326 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 3.54700509 |
| 3 | Colon cancer (HP:0003003) | 3.44095950 |
| 4 | Acute encephalopathy (HP:0006846) | 3.30679383 |
| 5 | Increased hepatocellular lipid droplets (HP:0006565) | 3.27850537 |
| 6 | Increased CSF lactate (HP:0002490) | 3.23834956 |
| 7 | Mitochondrial inheritance (HP:0001427) | 3.19782357 |
| 8 | Lipid accumulation in hepatocytes (HP:0006561) | 3.17584940 |
| 9 | Progressive macrocephaly (HP:0004481) | 3.08628032 |
| 10 | Methylmalonic acidemia (HP:0002912) | 3.00957155 |
| 11 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.96196433 |
| 12 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.90740013 |
| 13 | Pancreatic cysts (HP:0001737) | 2.84139733 |
| 14 | Congenital stationary night blindness (HP:0007642) | 2.81445232 |
| 15 | IgG deficiency (HP:0004315) | 2.78478114 |
| 16 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.61004356 |
| 17 | Abnormality of serum amino acid levels (HP:0003112) | 2.59916100 |
| 18 | Renal cortical cysts (HP:0000803) | 2.57545784 |
| 19 | Hyperglycinemia (HP:0002154) | 2.53088022 |
| 20 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.51729621 |
| 21 | Abnormality of alanine metabolism (HP:0010916) | 2.51729621 |
| 22 | Hyperalaninemia (HP:0003348) | 2.51729621 |
| 23 | Increased serum lactate (HP:0002151) | 2.51441953 |
| 24 | Renal Fanconi syndrome (HP:0001994) | 2.50356525 |
| 25 | Abnormality of methionine metabolism (HP:0010901) | 2.47643197 |
| 26 | Cerebral edema (HP:0002181) | 2.46730379 |
| 27 | Decreased central vision (HP:0007663) | 2.46237569 |
| 28 | True hermaphroditism (HP:0010459) | 2.45984858 |
| 29 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.45658431 |
| 30 | Pancreatic fibrosis (HP:0100732) | 2.45297098 |
| 31 | Abnormality of the pons (HP:0007361) | 2.42580971 |
| 32 | Hepatocellular necrosis (HP:0001404) | 2.40037543 |
| 33 | Bilateral microphthalmos (HP:0007633) | 2.38882710 |
| 34 | Abnormality of midbrain morphology (HP:0002418) | 2.35239734 |
| 35 | Molar tooth sign on MRI (HP:0002419) | 2.35239734 |
| 36 | Abnormality of the ileum (HP:0001549) | 2.34272820 |
| 37 | Meckel diverticulum (HP:0002245) | 2.32534837 |
| 38 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.31919568 |
| 39 | Ependymoma (HP:0002888) | 2.30047035 |
| 40 | Methylmalonic aciduria (HP:0012120) | 2.28593986 |
| 41 | Hypoplasia of the uterus (HP:0000013) | 2.27798889 |
| 42 | Nephronophthisis (HP:0000090) | 2.26869227 |
| 43 | Pendular nystagmus (HP:0012043) | 2.26404918 |
| 44 | Hepatic necrosis (HP:0002605) | 2.24479949 |
| 45 | Optic disc pallor (HP:0000543) | 2.20906400 |
| 46 | Hypoplasia of the fovea (HP:0007750) | 2.20798791 |
| 47 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.20798791 |
| 48 | Abnormal lung lobation (HP:0002101) | 2.20261779 |
| 49 | Abolished electroretinogram (ERG) (HP:0000550) | 2.19718042 |
| 50 | Pancytopenia (HP:0001876) | 2.17204856 |
| 51 | Type 2 muscle fiber atrophy (HP:0003554) | 2.14476760 |
| 52 | Stomach cancer (HP:0012126) | 2.13777424 |
| 53 | Exertional dyspnea (HP:0002875) | 2.12216474 |
| 54 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.11533355 |
| 55 | Abnormality of the preputium (HP:0100587) | 2.10902110 |
| 56 | Hypoplasia of the pons (HP:0012110) | 2.10030741 |
| 57 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.09547285 |
| 58 | Intestinal atresia (HP:0011100) | 2.07230687 |
| 59 | 3-Methylglutaconic aciduria (HP:0003535) | 2.06471673 |
| 60 | Lactic acidosis (HP:0003128) | 2.04739105 |
| 61 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.03261516 |
| 62 | Absent thumb (HP:0009777) | 2.02068871 |
| 63 | Abnormality of the renal cortex (HP:0011035) | 1.99676295 |
| 64 | Abnormality of glycine metabolism (HP:0010895) | 1.96947733 |
| 65 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.96947733 |
| 66 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.96844792 |
| 67 | Leukodystrophy (HP:0002415) | 1.95734366 |
| 68 | Cleft eyelid (HP:0000625) | 1.94493038 |
| 69 | Congenital, generalized hypertrichosis (HP:0004540) | 1.94436583 |
| 70 | Type II lissencephaly (HP:0007260) | 1.93640552 |
| 71 | Inability to walk (HP:0002540) | 1.90724464 |
| 72 | Small intestinal stenosis (HP:0012848) | 1.89951171 |
| 73 | Duodenal stenosis (HP:0100867) | 1.89951171 |
| 74 | Septo-optic dysplasia (HP:0100842) | 1.89847841 |
| 75 | Sclerocornea (HP:0000647) | 1.86128161 |
| 76 | Abnormality of vitamin B metabolism (HP:0004340) | 1.84964447 |
| 77 | Hyperglycinuria (HP:0003108) | 1.84278995 |
| 78 | Abnormality of the fovea (HP:0000493) | 1.83238367 |
| 79 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.82998481 |
| 80 | Lethargy (HP:0001254) | 1.82261656 |
| 81 | Agnosia (HP:0010524) | 1.80125385 |
| 82 | Type I transferrin isoform profile (HP:0003642) | 1.78618588 |
| 83 | Neoplasm of the adrenal cortex (HP:0100641) | 1.78380489 |
| 84 | Horseshoe kidney (HP:0000085) | 1.76365715 |
| 85 | Anophthalmia (HP:0000528) | 1.76307156 |
| 86 | Abnormal number of erythroid precursors (HP:0012131) | 1.76134512 |
| 87 | Abnormality of the duodenum (HP:0002246) | 1.74524670 |
| 88 | Triphalangeal thumb (HP:0001199) | 1.74437193 |
| 89 | Abnormality of the renal medulla (HP:0100957) | 1.73775699 |
| 90 | Muscle fiber atrophy (HP:0100295) | 1.72793477 |
| 91 | Glycosuria (HP:0003076) | 1.72720988 |
| 92 | Abnormality of urine glucose concentration (HP:0011016) | 1.72720988 |
| 93 | Gonadotropin excess (HP:0000837) | 1.72283748 |
| 94 | Constricted visual fields (HP:0001133) | 1.72216895 |
| 95 | Glioma (HP:0009733) | 1.71711230 |
| 96 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.71256619 |
| 97 | Medial flaring of the eyebrow (HP:0010747) | 1.70541030 |
| 98 | Abnormality of the prostate (HP:0008775) | 1.70152690 |
| 99 | Sensory axonal neuropathy (HP:0003390) | 1.68843465 |
| 100 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.68179129 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ZAK | 4.50806288 |
| 2 | BUB1 | 3.16498814 |
| 3 | VRK2 | 3.10533063 |
| 4 | PBK | 3.03163258 |
| 5 | TLK1 | 2.81496818 |
| 6 | NUAK1 | 2.53904636 |
| 7 | TSSK6 | 2.41492588 |
| 8 | PLK3 | 2.40391123 |
| 9 | VRK1 | 2.31653700 |
| 10 | PLK4 | 2.30232737 |
| 11 | WEE1 | 2.17924397 |
| 12 | TXK | 2.13931799 |
| 13 | FRK | 2.13771988 |
| 14 | EIF2AK3 | 2.12641864 |
| 15 | NEK1 | 2.08569020 |
| 16 | MKNK1 | 2.02714458 |
| 17 | BRSK2 | 1.91107562 |
| 18 | SRPK1 | 1.89738190 |
| 19 | WNK3 | 1.87025625 |
| 20 | MST4 | 1.83783779 |
| 21 | MKNK2 | 1.79515676 |
| 22 | TAF1 | 1.79010140 |
| 23 | MAP4K2 | 1.78295858 |
| 24 | ADRBK2 | 1.53711907 |
| 25 | PDK2 | 1.51930171 |
| 26 | EIF2AK1 | 1.47988785 |
| 27 | BMPR1B | 1.42236807 |
| 28 | STK16 | 1.41698692 |
| 29 | TRIM28 | 1.37022970 |
| 30 | NME1 | 1.33790018 |
| 31 | EIF2AK2 | 1.32891752 |
| 32 | GRK1 | 1.31212534 |
| 33 | ERBB3 | 1.25837539 |
| 34 | PLK2 | 1.21270161 |
| 35 | PASK | 1.16331954 |
| 36 | TTK | 1.14233801 |
| 37 | CDC7 | 1.14007008 |
| 38 | PINK1 | 1.13461415 |
| 39 | TAOK3 | 1.05899821 |
| 40 | PLK1 | 1.01249328 |
| 41 | TNIK | 1.00147719 |
| 42 | WNK4 | 0.97169544 |
| 43 | ATR | 0.95729835 |
| 44 | TEC | 0.92778824 |
| 45 | AURKB | 0.87426952 |
| 46 | DYRK2 | 0.84172971 |
| 47 | CHEK2 | 0.80580649 |
| 48 | NEK2 | 0.78248773 |
| 49 | GRK6 | 0.77228252 |
| 50 | ITK | 0.75941681 |
| 51 | CSNK1G1 | 0.75418969 |
| 52 | TGFBR1 | 0.73128021 |
| 53 | FGFR2 | 0.67782477 |
| 54 | ALK | 0.64825185 |
| 55 | CSNK1G3 | 0.64244740 |
| 56 | STK39 | 0.63075162 |
| 57 | OXSR1 | 0.62606870 |
| 58 | GRK5 | 0.61167671 |
| 59 | BRSK1 | 0.60298481 |
| 60 | STK4 | 0.60271605 |
| 61 | BCKDK | 0.59561529 |
| 62 | EPHB2 | 0.57370541 |
| 63 | TIE1 | 0.56943221 |
| 64 | CDK3 | 0.56768219 |
| 65 | WNK1 | 0.54099812 |
| 66 | PIK3CG | 0.53503008 |
| 67 | PRKCG | 0.52779575 |
| 68 | CSNK1A1L | 0.49602878 |
| 69 | DAPK1 | 0.48562043 |
| 70 | INSRR | 0.47944378 |
| 71 | IKBKB | 0.47555296 |
| 72 | TESK2 | 0.47140328 |
| 73 | ERBB2 | 0.46639757 |
| 74 | ATM | 0.46549746 |
| 75 | ACVR1B | 0.46055402 |
| 76 | RPS6KA5 | 0.45216536 |
| 77 | MAP3K4 | 0.42023905 |
| 78 | CSNK1G2 | 0.41635331 |
| 79 | CSNK2A1 | 0.40472603 |
| 80 | CSNK2A2 | 0.38960358 |
| 81 | SYK | 0.38128166 |
| 82 | IGF1R | 0.35361369 |
| 83 | PIM1 | 0.34031684 |
| 84 | CHEK1 | 0.33386703 |
| 85 | STK38L | 0.32126160 |
| 86 | CSNK1E | 0.31678580 |
| 87 | CSNK1A1 | 0.31645173 |
| 88 | CDK7 | 0.31185327 |
| 89 | MARK3 | 0.31017420 |
| 90 | MAP4K1 | 0.28733746 |
| 91 | FGFR1 | 0.27788186 |
| 92 | MAPKAPK5 | 0.25783740 |
| 93 | PRKCA | 0.24755929 |
| 94 | PKN1 | 0.24184615 |
| 95 | PTK2B | 0.24073198 |
| 96 | LYN | 0.23990370 |
| 97 | PHKG1 | 0.23923336 |
| 98 | PHKG2 | 0.23923336 |
| 99 | ADRBK1 | 0.23541558 |
| 100 | PRKCQ | 0.22819451 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 3.73761716 |
| 2 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.94740769 |
| 3 | Ribosome_Homo sapiens_hsa03010 | 2.70004067 |
| 4 | Protein export_Homo sapiens_hsa03060 | 2.66323586 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 2.64629910 |
| 6 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.51778551 |
| 7 | Mismatch repair_Homo sapiens_hsa03430 | 2.48021069 |
| 8 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.37413716 |
| 9 | DNA replication_Homo sapiens_hsa03030 | 2.33994073 |
| 10 | Asthma_Homo sapiens_hsa05310 | 2.33724739 |
| 11 | Homologous recombination_Homo sapiens_hsa03440 | 2.31327041 |
| 12 | RNA degradation_Homo sapiens_hsa03018 | 2.08192773 |
| 13 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.07465113 |
| 14 | Parkinsons disease_Homo sapiens_hsa05012 | 2.06103577 |
| 15 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.97956096 |
| 16 | Base excision repair_Homo sapiens_hsa03410 | 1.96613641 |
| 17 | Basal transcription factors_Homo sapiens_hsa03022 | 1.96108553 |
| 18 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.94340823 |
| 19 | Allograft rejection_Homo sapiens_hsa05330 | 1.90498781 |
| 20 | Spliceosome_Homo sapiens_hsa03040 | 1.88690460 |
| 21 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.88106649 |
| 22 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.82227456 |
| 23 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.81250114 |
| 24 | RNA transport_Homo sapiens_hsa03013 | 1.75578531 |
| 25 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.74128388 |
| 26 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.56941895 |
| 27 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.54551281 |
| 28 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.54212601 |
| 29 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.47576109 |
| 30 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.36994197 |
| 31 | Huntingtons disease_Homo sapiens_hsa05016 | 1.36540293 |
| 32 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.27959805 |
| 33 | Purine metabolism_Homo sapiens_hsa00230 | 1.27410872 |
| 34 | Phototransduction_Homo sapiens_hsa04744 | 1.23353836 |
| 35 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.20642999 |
| 36 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.19497089 |
| 37 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.19010256 |
| 38 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.18757462 |
| 39 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.14080774 |
| 40 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.13224707 |
| 41 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.12752554 |
| 42 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.11347559 |
| 43 | Alzheimers disease_Homo sapiens_hsa05010 | 1.09398954 |
| 44 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.99426426 |
| 45 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.97758204 |
| 46 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.95592042 |
| 47 | Cell cycle_Homo sapiens_hsa04110 | 0.94130832 |
| 48 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.90534104 |
| 49 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.87546149 |
| 50 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.87345979 |
| 51 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.85002154 |
| 52 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.84852669 |
| 53 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.82627426 |
| 54 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.78462248 |
| 55 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.73052093 |
| 56 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.70992137 |
| 57 | Peroxisome_Homo sapiens_hsa04146 | 0.69643128 |
| 58 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.68557447 |
| 59 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.68107221 |
| 60 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.67734904 |
| 61 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.66539990 |
| 62 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.65722004 |
| 63 | Metabolic pathways_Homo sapiens_hsa01100 | 0.63965659 |
| 64 | Olfactory transduction_Homo sapiens_hsa04740 | 0.63441068 |
| 65 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.63228940 |
| 66 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.63107220 |
| 67 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.57628638 |
| 68 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.57322469 |
| 69 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.56688278 |
| 70 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.56462115 |
| 71 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.54298396 |
| 72 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.53548993 |
| 73 | Nicotine addiction_Homo sapiens_hsa05033 | 0.51944052 |
| 74 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.51914521 |
| 75 | Carbon metabolism_Homo sapiens_hsa01200 | 0.50913280 |
| 76 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.50516087 |
| 77 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.49863226 |
| 78 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.49412587 |
| 79 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.48367381 |
| 80 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.47487309 |
| 81 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.45094145 |
| 82 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.44784396 |
| 83 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.44493922 |
| 84 | Retinol metabolism_Homo sapiens_hsa00830 | 0.44042904 |
| 85 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.42625520 |
| 86 | Alcoholism_Homo sapiens_hsa05034 | 0.41526096 |
| 87 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.41514206 |
| 88 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.40693563 |
| 89 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.40578245 |
| 90 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.40117275 |
| 91 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.40068588 |
| 92 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.37691431 |
| 93 | Taste transduction_Homo sapiens_hsa04742 | 0.37078437 |
| 94 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.37018771 |
| 95 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.36408844 |
| 96 | Sulfur relay system_Homo sapiens_hsa04122 | 0.35902068 |
| 97 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.33564540 |
| 98 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.33484853 |
| 99 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.32986553 |
| 100 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.32473513 |

