

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 7.25546029 |
| 2 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 7.23972697 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.54010133 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 6.54010133 |
| 5 | cytidine deamination (GO:0009972) | 6.02162958 |
| 6 | cytidine metabolic process (GO:0046087) | 6.02162958 |
| 7 | cytidine catabolic process (GO:0006216) | 6.02162958 |
| 8 | ribosomal small subunit assembly (GO:0000028) | 5.87115647 |
| 9 | DNA deamination (GO:0045006) | 5.69908343 |
| 10 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.64408179 |
| 11 | viral transcription (GO:0019083) | 5.57882165 |
| 12 | translational termination (GO:0006415) | 5.37414201 |
| 13 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 5.17747818 |
| 14 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.08345172 |
| 15 | cotranslational protein targeting to membrane (GO:0006613) | 5.02211755 |
| 16 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.01097210 |
| 17 | protein targeting to ER (GO:0045047) | 4.94861803 |
| 18 | translational elongation (GO:0006414) | 4.79294755 |
| 19 | respiratory electron transport chain (GO:0022904) | 4.77925639 |
| 20 | electron transport chain (GO:0022900) | 4.72256928 |
| 21 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.67917650 |
| 22 | maturation of SSU-rRNA (GO:0030490) | 4.64746153 |
| 23 | protein localization to endoplasmic reticulum (GO:0070972) | 4.61608322 |
| 24 | proteasome assembly (GO:0043248) | 4.37871501 |
| 25 | chaperone-mediated protein transport (GO:0072321) | 4.26665453 |
| 26 | response to pheromone (GO:0019236) | 4.23252152 |
| 27 | protein neddylation (GO:0045116) | 4.15551502 |
| 28 | cellular protein complex disassembly (GO:0043624) | 4.05300047 |
| 29 | viral life cycle (GO:0019058) | 4.04955001 |
| 30 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.98186600 |
| 31 | termination of RNA polymerase III transcription (GO:0006386) | 3.98186600 |
| 32 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.95659756 |
| 33 | tryptophan catabolic process (GO:0006569) | 3.90243734 |
| 34 | indole-containing compound catabolic process (GO:0042436) | 3.90243734 |
| 35 | indolalkylamine catabolic process (GO:0046218) | 3.90243734 |
| 36 | protein complex biogenesis (GO:0070271) | 3.89049382 |
| 37 | ribosomal large subunit biogenesis (GO:0042273) | 3.88687634 |
| 38 | sequestering of actin monomers (GO:0042989) | 3.77877713 |
| 39 | translation (GO:0006412) | 3.77680432 |
| 40 | inner mitochondrial membrane organization (GO:0007007) | 3.77389492 |
| 41 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.73644264 |
| 42 | translational initiation (GO:0006413) | 3.67785552 |
| 43 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.67582841 |
| 44 | ribosomal small subunit biogenesis (GO:0042274) | 3.64858136 |
| 45 | intracellular protein transmembrane import (GO:0044743) | 3.63065651 |
| 46 | ATP biosynthetic process (GO:0006754) | 3.61559701 |
| 47 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.56008527 |
| 48 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.55954220 |
| 49 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.44406509 |
| 50 | regulation of chronic inflammatory response (GO:0002676) | 3.40771172 |
| 51 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.35213306 |
| 52 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.33389250 |
| 53 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.33389250 |
| 54 | NADH dehydrogenase complex assembly (GO:0010257) | 3.33389250 |
| 55 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.33385428 |
| 56 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.31774451 |
| 57 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.31774451 |
| 58 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.31774451 |
| 59 | hydrogen ion transmembrane transport (GO:1902600) | 3.30490791 |
| 60 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.25913108 |
| 61 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.25913108 |
| 62 | protein targeting to membrane (GO:0006612) | 3.24875531 |
| 63 | protein complex disassembly (GO:0043241) | 3.24865384 |
| 64 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.20671255 |
| 65 | oxidative phosphorylation (GO:0006119) | 3.19961793 |
| 66 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.19708397 |
| 67 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.18176508 |
| 68 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.16386634 |
| 69 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.16386634 |
| 70 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.13846765 |
| 71 | macromolecular complex disassembly (GO:0032984) | 3.11448680 |
| 72 | proton transport (GO:0015992) | 3.07331132 |
| 73 | kynurenine metabolic process (GO:0070189) | 3.06984605 |
| 74 | negative regulation of ligase activity (GO:0051352) | 3.06246326 |
| 75 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.06246326 |
| 76 | spliceosomal complex assembly (GO:0000245) | 3.05134885 |
| 77 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.04259577 |
| 78 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.02661783 |
| 79 | tryptophan metabolic process (GO:0006568) | 3.00698461 |
| 80 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.99880248 |
| 81 | indolalkylamine metabolic process (GO:0006586) | 2.98963174 |
| 82 | hydrogen transport (GO:0006818) | 2.98672948 |
| 83 | cytochrome complex assembly (GO:0017004) | 2.95802122 |
| 84 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.93508164 |
| 85 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.93508164 |
| 86 | behavioral response to nicotine (GO:0035095) | 2.92351638 |
| 87 | protein-cofactor linkage (GO:0018065) | 2.92289742 |
| 88 | spliceosomal snRNP assembly (GO:0000387) | 2.91038123 |
| 89 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.89920506 |
| 90 | cell wall macromolecule metabolic process (GO:0044036) | 2.88813692 |
| 91 | mRNA catabolic process (GO:0006402) | 2.85723136 |
| 92 | intracellular protein transmembrane transport (GO:0065002) | 2.85372419 |
| 93 | iron-sulfur cluster assembly (GO:0016226) | 2.84072598 |
| 94 | metallo-sulfur cluster assembly (GO:0031163) | 2.84072598 |
| 95 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.83194435 |
| 96 | respiratory chain complex IV assembly (GO:0008535) | 2.80250439 |
| 97 | cytolysis (GO:0019835) | 2.76068106 |
| 98 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.71165848 |
| 99 | RNA catabolic process (GO:0006401) | 2.70661379 |
| 100 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.70585125 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.48138548 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.20274903 |
| 3 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.07705883 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.94502957 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.81750401 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.18835800 |
| 7 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.91051428 |
| 8 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.86586867 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.85953325 |
| 10 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.67661075 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.61000232 |
| 12 | VDR_22108803_ChIP-Seq_LS180_Human | 2.52981741 |
| 13 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.45546603 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.44952460 |
| 15 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.37670903 |
| 16 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.16044283 |
| 17 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.14958786 |
| 18 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.09170294 |
| 19 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.07642936 |
| 20 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.06408879 |
| 21 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.04428138 |
| 22 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.84142077 |
| 23 | EWS_26573619_Chip-Seq_HEK293_Human | 1.83732496 |
| 24 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.81571051 |
| 25 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.80310339 |
| 26 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.72007945 |
| 27 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.65992678 |
| 28 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.63689358 |
| 29 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.60739935 |
| 30 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.60400727 |
| 31 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.58474009 |
| 32 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.56345325 |
| 33 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.54355257 |
| 34 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.54293288 |
| 35 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.52864870 |
| 36 | FUS_26573619_Chip-Seq_HEK293_Human | 1.52730001 |
| 37 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.50809039 |
| 38 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.48662653 |
| 39 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.44912177 |
| 40 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.41215734 |
| 41 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.39629834 |
| 42 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.39091782 |
| 43 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.34856941 |
| 44 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.31682579 |
| 45 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.31374672 |
| 46 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.28330987 |
| 47 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.27117209 |
| 48 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.25914640 |
| 49 | AR_20517297_ChIP-Seq_VCAP_Human | 1.25578941 |
| 50 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.25223790 |
| 51 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.25090110 |
| 52 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.24573532 |
| 53 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.24419601 |
| 54 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.24105327 |
| 55 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.23318751 |
| 56 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.23054289 |
| 57 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.22909330 |
| 58 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.20083621 |
| 59 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.19926343 |
| 60 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.18049989 |
| 61 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.17934061 |
| 62 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.15979158 |
| 63 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.14830059 |
| 64 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.14064512 |
| 65 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.14056452 |
| 66 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.13851461 |
| 67 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.12671806 |
| 68 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.12052986 |
| 69 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.10765733 |
| 70 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.09821669 |
| 71 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.07834198 |
| 72 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.07834198 |
| 73 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.07580561 |
| 74 | GATA3_26560356_Chip-Seq_TH2_Human | 1.06433104 |
| 75 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.06221146 |
| 76 | P300_19829295_ChIP-Seq_ESCs_Human | 1.05601516 |
| 77 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.05356641 |
| 78 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.05327970 |
| 79 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.05199250 |
| 80 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.03933731 |
| 81 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.02498619 |
| 82 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.02498619 |
| 83 | NCOR_22424771_ChIP-Seq_293T_Human | 1.02052490 |
| 84 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.01965802 |
| 85 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.00499737 |
| 86 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.99731299 |
| 87 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.99731299 |
| 88 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.98190053 |
| 89 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.97871060 |
| 90 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.97350417 |
| 91 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.95370512 |
| 92 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.95199904 |
| 93 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.95003717 |
| 94 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.93999908 |
| 95 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.92469273 |
| 96 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.91883349 |
| 97 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.90999142 |
| 98 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.89935438 |
| 99 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.89531487 |
| 100 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.86505956 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 4.43709734 |
| 2 | MP0006292_abnormal_olfactory_placode | 4.35083041 |
| 3 | MP0005671_abnormal_response_to | 3.74586968 |
| 4 | MP0003878_abnormal_ear_physiology | 2.59673653 |
| 5 | MP0005377_hearing/vestibular/ear_phenot | 2.59673653 |
| 6 | MP0008875_abnormal_xenobiotic_pharmacok | 2.49565058 |
| 7 | MP0005084_abnormal_gallbladder_morpholo | 2.46101988 |
| 8 | MP0009785_altered_susceptibility_to | 2.22901585 |
| 9 | MP0008058_abnormal_DNA_repair | 2.16857784 |
| 10 | MP0003136_yellow_coat_color | 2.08960578 |
| 11 | MP0008872_abnormal_physiological_respon | 2.06391837 |
| 12 | MP0002102_abnormal_ear_morphology | 2.04563761 |
| 13 | MP0003880_abnormal_central_pattern | 1.91881661 |
| 14 | MP0001873_stomach_inflammation | 1.87965604 |
| 15 | MP0001485_abnormal_pinna_reflex | 1.86605516 |
| 16 | MP0006082_CNS_inflammation | 1.83783520 |
| 17 | MP0006072_abnormal_retinal_apoptosis | 1.83237927 |
| 18 | MP0001835_abnormal_antigen_presentation | 1.79967884 |
| 19 | MP0009333_abnormal_splenocyte_physiolog | 1.75934754 |
| 20 | MP0003567_abnormal_fetal_cardiomyocyte | 1.68547445 |
| 21 | MP0004142_abnormal_muscle_tone | 1.62523292 |
| 22 | MP0005645_abnormal_hypothalamus_physiol | 1.62087577 |
| 23 | MP0002095_abnormal_skin_pigmentation | 1.55278224 |
| 24 | MP0003763_abnormal_thymus_physiology | 1.54045568 |
| 25 | MP0008877_abnormal_DNA_methylation | 1.52363255 |
| 26 | MP0002938_white_spotting | 1.52358360 |
| 27 | MP0005551_abnormal_eye_electrophysiolog | 1.51117108 |
| 28 | MP0002148_abnormal_hypersensitivity_rea | 1.49980323 |
| 29 | MP0003950_abnormal_plasma_membrane | 1.48134684 |
| 30 | MP0002736_abnormal_nociception_after | 1.45017672 |
| 31 | MP0003866_abnormal_defecation | 1.44892380 |
| 32 | MP0004145_abnormal_muscle_electrophysio | 1.42994531 |
| 33 | MP0002277_abnormal_respiratory_mucosa | 1.40430170 |
| 34 | MP0004885_abnormal_endolymph | 1.38772672 |
| 35 | MP0005646_abnormal_pituitary_gland | 1.37510867 |
| 36 | MP0000685_abnormal_immune_system | 1.35300172 |
| 37 | MP0002638_abnormal_pupillary_reflex | 1.35110646 |
| 38 | MP0002138_abnormal_hepatobiliary_system | 1.34211789 |
| 39 | MP0001800_abnormal_humoral_immune | 1.33400270 |
| 40 | MP0004133_heterotaxia | 1.31281957 |
| 41 | MP0000372_irregular_coat_pigmentation | 1.28798238 |
| 42 | MP0005253_abnormal_eye_physiology | 1.27299382 |
| 43 | MP0005410_abnormal_fertilization | 1.26679933 |
| 44 | MP0001905_abnormal_dopamine_level | 1.22837167 |
| 45 | MP0003011_delayed_dark_adaptation | 1.19968936 |
| 46 | MP0008995_early_reproductive_senescence | 1.19817269 |
| 47 | MP0006035_abnormal_mitochondrial_morpho | 1.19387396 |
| 48 | MP0002234_abnormal_pharynx_morphology | 1.17126333 |
| 49 | MP0005000_abnormal_immune_tolerance | 1.16797712 |
| 50 | MP0002876_abnormal_thyroid_physiology | 1.16675570 |
| 51 | MP0001968_abnormal_touch/_nociception | 1.15457638 |
| 52 | MP0003195_calcinosis | 1.14970272 |
| 53 | MP0005387_immune_system_phenotype | 1.12941026 |
| 54 | MP0001790_abnormal_immune_system | 1.12941026 |
| 55 | MP0006036_abnormal_mitochondrial_physio | 1.12785645 |
| 56 | MP0001348_abnormal_lacrimal_gland | 1.12609659 |
| 57 | MP0010030_abnormal_orbit_morphology | 1.09909710 |
| 58 | MP0002160_abnormal_reproductive_system | 1.08917749 |
| 59 | MP0002006_tumorigenesis | 1.07262466 |
| 60 | MP0002723_abnormal_immune_serum | 1.03560844 |
| 61 | MP0002166_altered_tumor_susceptibility | 1.03022226 |
| 62 | MP0003786_premature_aging | 1.02652514 |
| 63 | MP0002420_abnormal_adaptive_immunity | 1.02520708 |
| 64 | MP0001764_abnormal_homeostasis | 1.01412881 |
| 65 | MP0001819_abnormal_immune_cell | 1.00193294 |
| 66 | MP0000049_abnormal_middle_ear | 0.99302951 |
| 67 | MP0002837_dystrophic_cardiac_calcinosis | 0.98158622 |
| 68 | MP0000631_abnormal_neuroendocrine_gland | 0.97766269 |
| 69 | MP0001293_anophthalmia | 0.96642315 |
| 70 | MP0005025_abnormal_response_to | 0.96333362 |
| 71 | MP0003938_abnormal_ear_development | 0.96220450 |
| 72 | MP0003137_abnormal_impulse_conducting | 0.92574645 |
| 73 | MP0008789_abnormal_olfactory_epithelium | 0.91019065 |
| 74 | MP0001919_abnormal_reproductive_system | 0.89976625 |
| 75 | MP0001529_abnormal_vocalization | 0.89599961 |
| 76 | MP0003186_abnormal_redox_activity | 0.87773989 |
| 77 | MP0000716_abnormal_immune_system | 0.86691678 |
| 78 | MP0005389_reproductive_system_phenotype | 0.86463291 |
| 79 | MP0001486_abnormal_startle_reflex | 0.85340184 |
| 80 | MP0004957_abnormal_blastocyst_morpholog | 0.84958249 |
| 81 | MP0002396_abnormal_hematopoietic_system | 0.84829584 |
| 82 | MP0001346_abnormal_lacrimal_gland | 0.84438841 |
| 83 | MP0005195_abnormal_posterior_eye | 0.83551309 |
| 84 | MP0001666_abnormal_nutrient_absorption | 0.81933129 |
| 85 | MP0005085_abnormal_gallbladder_physiolo | 0.80352402 |
| 86 | MP0005075_abnormal_melanosome_morpholog | 0.79932038 |
| 87 | MP0010155_abnormal_intestine_physiology | 0.79268384 |
| 88 | MP0003283_abnormal_digestive_organ | 0.78940869 |
| 89 | MP0010094_abnormal_chromosome_stability | 0.78690309 |
| 90 | MP0002405_respiratory_system_inflammati | 0.77878840 |
| 91 | MP0000703_abnormal_thymus_morphology | 0.77789269 |
| 92 | MP0003936_abnormal_reproductive_system | 0.76812209 |
| 93 | MP0002452_abnormal_antigen_presenting | 0.75928595 |
| 94 | MP0002398_abnormal_bone_marrow | 0.75632568 |
| 95 | MP0009745_abnormal_behavioral_response | 0.74965971 |
| 96 | MP0001845_abnormal_inflammatory_respons | 0.74749250 |
| 97 | MP0001502_abnormal_circadian_rhythm | 0.73812140 |
| 98 | MP0001663_abnormal_digestive_system | 0.71635200 |
| 99 | MP0000026_abnormal_inner_ear | 0.68433125 |
| 100 | MP0006276_abnormal_autonomic_nervous | 0.66826761 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.65108224 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.30036111 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.03009355 |
| 4 | Aplastic anemia (HP:0001915) | 3.94532996 |
| 5 | Hepatocellular necrosis (HP:0001404) | 3.85141620 |
| 6 | Acute encephalopathy (HP:0006846) | 3.80367020 |
| 7 | Progressive macrocephaly (HP:0004481) | 3.76638645 |
| 8 | 3-Methylglutaconic aciduria (HP:0003535) | 3.71214493 |
| 9 | Increased CSF lactate (HP:0002490) | 3.68297942 |
| 10 | Pancreatic cysts (HP:0001737) | 3.66338728 |
| 11 | Reticulocytopenia (HP:0001896) | 3.64757556 |
| 12 | Autoimmune thrombocytopenia (HP:0001973) | 3.63169526 |
| 13 | True hermaphroditism (HP:0010459) | 3.59310878 |
| 14 | Autoimmune hemolytic anemia (HP:0001890) | 3.37419871 |
| 15 | Colon cancer (HP:0003003) | 3.36871292 |
| 16 | Hepatic necrosis (HP:0002605) | 3.36182984 |
| 17 | Abnormality of B cell number (HP:0010975) | 3.25177014 |
| 18 | Increased hepatocellular lipid droplets (HP:0006565) | 3.25018947 |
| 19 | Macrocytic anemia (HP:0001972) | 3.09188742 |
| 20 | Pancreatic fibrosis (HP:0100732) | 3.00419052 |
| 21 | Methylmalonic acidemia (HP:0002912) | 2.96616552 |
| 22 | Cerebral edema (HP:0002181) | 2.93651933 |
| 23 | Lipid accumulation in hepatocytes (HP:0006561) | 2.90356325 |
| 24 | Congenital, generalized hypertrichosis (HP:0004540) | 2.75556192 |
| 25 | Congenital stationary night blindness (HP:0007642) | 2.74071319 |
| 26 | Optic disc pallor (HP:0000543) | 2.71155600 |
| 27 | Stomach cancer (HP:0012126) | 2.60788576 |
| 28 | Pendular nystagmus (HP:0012043) | 2.57008226 |
| 29 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.55860071 |
| 30 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.55046270 |
| 31 | Sclerocornea (HP:0000647) | 2.52214974 |
| 32 | Abnormal number of erythroid precursors (HP:0012131) | 2.50784594 |
| 33 | Methylmalonic aciduria (HP:0012120) | 2.47847367 |
| 34 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.47504272 |
| 35 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.44735282 |
| 36 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.44735282 |
| 37 | Respiratory failure (HP:0002878) | 2.44688276 |
| 38 | Renal Fanconi syndrome (HP:0001994) | 2.44470879 |
| 39 | Abnormality of midbrain morphology (HP:0002418) | 2.42611251 |
| 40 | Molar tooth sign on MRI (HP:0002419) | 2.42611251 |
| 41 | Pallor (HP:0000980) | 2.40637036 |
| 42 | Increased serum lactate (HP:0002151) | 2.37385079 |
| 43 | Increased IgM level (HP:0003496) | 2.37061171 |
| 44 | Bile duct proliferation (HP:0001408) | 2.32948038 |
| 45 | Abnormal biliary tract physiology (HP:0012439) | 2.32948038 |
| 46 | Leukodystrophy (HP:0002415) | 2.32182948 |
| 47 | Hypoproteinemia (HP:0003075) | 2.31762888 |
| 48 | Septo-optic dysplasia (HP:0100842) | 2.30877839 |
| 49 | Abnormality of T cell number (HP:0011839) | 2.28415291 |
| 50 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.25231679 |
| 51 | Oral leukoplakia (HP:0002745) | 2.24487944 |
| 52 | Lactic acidosis (HP:0003128) | 2.19448831 |
| 53 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.17098726 |
| 54 | Pancytopenia (HP:0001876) | 2.16458024 |
| 55 | Nephronophthisis (HP:0000090) | 2.14713995 |
| 56 | Medial flaring of the eyebrow (HP:0010747) | 2.13518224 |
| 57 | Abolished electroretinogram (ERG) (HP:0000550) | 2.13467873 |
| 58 | B lymphocytopenia (HP:0010976) | 2.09169535 |
| 59 | Attenuation of retinal blood vessels (HP:0007843) | 2.07698168 |
| 60 | IgG deficiency (HP:0004315) | 2.07584934 |
| 61 | Megaloblastic anemia (HP:0001889) | 2.01751531 |
| 62 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.99030238 |
| 63 | Exertional dyspnea (HP:0002875) | 1.98874554 |
| 64 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.98546477 |
| 65 | Severe combined immunodeficiency (HP:0004430) | 1.98148626 |
| 66 | Fibular aplasia (HP:0002990) | 1.98018026 |
| 67 | Abnormality of T cells (HP:0002843) | 1.97277617 |
| 68 | Lethargy (HP:0001254) | 1.95079812 |
| 69 | Central scotoma (HP:0000603) | 1.94990728 |
| 70 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 1.93965479 |
| 71 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.93687500 |
| 72 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.92366830 |
| 73 | Abnormality of the ileum (HP:0001549) | 1.92287796 |
| 74 | Meckel diverticulum (HP:0002245) | 1.91401513 |
| 75 | Dyschromatopsia (HP:0007641) | 1.90737079 |
| 76 | Cellular immunodeficiency (HP:0005374) | 1.89808082 |
| 77 | Abnormal number of incisors (HP:0011064) | 1.88803421 |
| 78 | Hypokalemic alkalosis (HP:0001949) | 1.88757904 |
| 79 | Abnormality of the renal cortex (HP:0011035) | 1.87520389 |
| 80 | Male pseudohermaphroditism (HP:0000037) | 1.85954120 |
| 81 | Postaxial foot polydactyly (HP:0001830) | 1.85885811 |
| 82 | Testicular atrophy (HP:0000029) | 1.84214488 |
| 83 | Absent thumb (HP:0009777) | 1.83355927 |
| 84 | Cystic liver disease (HP:0006706) | 1.82907169 |
| 85 | Anencephaly (HP:0002323) | 1.82607014 |
| 86 | Triphalangeal thumb (HP:0001199) | 1.82218190 |
| 87 | Maternal diabetes (HP:0009800) | 1.82196356 |
| 88 | T lymphocytopenia (HP:0005403) | 1.81458396 |
| 89 | Constricted visual fields (HP:0001133) | 1.81362919 |
| 90 | Abnormality of vitamin B metabolism (HP:0004340) | 1.80868999 |
| 91 | Abnormality of the pons (HP:0007361) | 1.80335628 |
| 92 | Hypoalbuminemia (HP:0003073) | 1.79827849 |
| 93 | Abnormal albumin level (HP:0012116) | 1.79827849 |
| 94 | Increased intramyocellular lipid droplets (HP:0012240) | 1.79593117 |
| 95 | Hypoplasia of the ulna (HP:0003022) | 1.79127796 |
| 96 | Abnormality of the prostate (HP:0008775) | 1.78011144 |
| 97 | Stenosis of the external auditory canal (HP:0000402) | 1.76253672 |
| 98 | Renal cortical cysts (HP:0000803) | 1.75823692 |
| 99 | Abnormality of eosinophils (HP:0001879) | 1.73927183 |
| 100 | Abnormality of renal resorption (HP:0011038) | 1.73215907 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 4.04095530 |
| 2 | ZAK | 3.72919927 |
| 3 | PASK | 3.72314810 |
| 4 | TXK | 3.03876714 |
| 5 | PNCK | 2.61526334 |
| 6 | VRK1 | 2.51850652 |
| 7 | KDR | 2.28801212 |
| 8 | BUB1 | 2.28466308 |
| 9 | ADRBK2 | 2.28408638 |
| 10 | NEK1 | 2.20903085 |
| 11 | MAP4K1 | 2.19631444 |
| 12 | MAP4K2 | 2.19271910 |
| 13 | MST4 | 2.18737306 |
| 14 | EPHA4 | 2.15153633 |
| 15 | TLK1 | 2.06283303 |
| 16 | WEE1 | 1.87060281 |
| 17 | STK16 | 1.83454394 |
| 18 | NME1 | 1.80236992 |
| 19 | EIF2AK3 | 1.78425286 |
| 20 | WNK4 | 1.72094872 |
| 21 | SRPK1 | 1.72058246 |
| 22 | TAF1 | 1.67465912 |
| 23 | GRK1 | 1.62759431 |
| 24 | TRIM28 | 1.60439207 |
| 25 | TSSK6 | 1.58820023 |
| 26 | BCKDK | 1.57252595 |
| 27 | PINK1 | 1.47097421 |
| 28 | PLK3 | 1.46488325 |
| 29 | ITK | 1.42904375 |
| 30 | NUAK1 | 1.35966874 |
| 31 | BRSK2 | 1.31091680 |
| 32 | INSRR | 1.28084475 |
| 33 | PBK | 1.12932547 |
| 34 | MAPKAPK3 | 1.11100447 |
| 35 | PIK3CA | 1.09212115 |
| 36 | MAP3K11 | 1.04237741 |
| 37 | DYRK2 | 1.02454857 |
| 38 | MKNK1 | 1.02371509 |
| 39 | MAPK15 | 1.02247359 |
| 40 | MAP3K12 | 1.01895311 |
| 41 | WNK3 | 1.00277651 |
| 42 | TESK2 | 0.99654760 |
| 43 | FRK | 0.97410282 |
| 44 | CDC7 | 0.91186008 |
| 45 | PRKCQ | 0.89645490 |
| 46 | EIF2AK2 | 0.87193243 |
| 47 | TEC | 0.84486059 |
| 48 | EIF2AK1 | 0.83393295 |
| 49 | CHEK2 | 0.79982933 |
| 50 | TIE1 | 0.76318425 |
| 51 | SYK | 0.75847500 |
| 52 | ADRBK1 | 0.73063329 |
| 53 | IKBKE | 0.72021399 |
| 54 | FES | 0.68068303 |
| 55 | NTRK3 | 0.67562820 |
| 56 | LYN | 0.66874409 |
| 57 | MARK3 | 0.66151415 |
| 58 | CAMKK2 | 0.64684004 |
| 59 | LCK | 0.61130985 |
| 60 | JAK3 | 0.60430168 |
| 61 | STK38L | 0.60360896 |
| 62 | CDK19 | 0.60062436 |
| 63 | ATR | 0.59897890 |
| 64 | PRKCG | 0.58101467 |
| 65 | MAPKAPK5 | 0.57171732 |
| 66 | TGFBR1 | 0.57048275 |
| 67 | CSNK2A1 | 0.56176524 |
| 68 | GRK6 | 0.53581955 |
| 69 | GRK7 | 0.52148501 |
| 70 | IKBKB | 0.51276264 |
| 71 | CAMKK1 | 0.51031440 |
| 72 | CSNK2A2 | 0.48915052 |
| 73 | RPS6KB1 | 0.48236663 |
| 74 | OBSCN | 0.47387596 |
| 75 | OXSR1 | 0.46990289 |
| 76 | AURKB | 0.45840251 |
| 77 | DAPK1 | 0.45649457 |
| 78 | DAPK2 | 0.44845255 |
| 79 | BTK | 0.44541653 |
| 80 | RPS6KA5 | 0.43954756 |
| 81 | PIK3CG | 0.43255402 |
| 82 | PLK1 | 0.43103237 |
| 83 | MAP2K7 | 0.42044991 |
| 84 | PLK2 | 0.39974096 |
| 85 | PRKCA | 0.39692381 |
| 86 | DAPK3 | 0.39272688 |
| 87 | PRKACA | 0.38358006 |
| 88 | BRSK1 | 0.37454186 |
| 89 | MATK | 0.36852144 |
| 90 | MYLK | 0.36208364 |
| 91 | TYRO3 | 0.36034673 |
| 92 | BMPR1B | 0.35695664 |
| 93 | RPS6KA4 | 0.35639708 |
| 94 | RPS6KB2 | 0.34912203 |
| 95 | FGFR1 | 0.34566881 |
| 96 | IGF1R | 0.34188070 |
| 97 | CSNK1A1 | 0.33114312 |
| 98 | PRKCI | 0.32541003 |
| 99 | PIM1 | 0.32528505 |
| 100 | MAP3K5 | 0.31483201 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.87711731 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 4.50026786 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.27592388 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.57165432 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 2.80147160 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.77491677 |
| 7 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.64088908 |
| 8 | Huntingtons disease_Homo sapiens_hsa05016 | 2.41841858 |
| 9 | Alzheimers disease_Homo sapiens_hsa05010 | 2.28804644 |
| 10 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.24524826 |
| 11 | Homologous recombination_Homo sapiens_hsa03440 | 2.16462583 |
| 12 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.10422228 |
| 13 | Allograft rejection_Homo sapiens_hsa05330 | 1.97476872 |
| 14 | Mismatch repair_Homo sapiens_hsa03430 | 1.87674429 |
| 15 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.86748238 |
| 16 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.85264219 |
| 17 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.78694696 |
| 18 | Asthma_Homo sapiens_hsa05310 | 1.77936880 |
| 19 | Spliceosome_Homo sapiens_hsa03040 | 1.77665033 |
| 20 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.77513764 |
| 21 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.70087719 |
| 22 | DNA replication_Homo sapiens_hsa03030 | 1.63507729 |
| 23 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.59272709 |
| 24 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.49252413 |
| 25 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.42026289 |
| 26 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.37596808 |
| 27 | RNA degradation_Homo sapiens_hsa03018 | 1.35126435 |
| 28 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.34506067 |
| 29 | Phototransduction_Homo sapiens_hsa04744 | 1.29713626 |
| 30 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.27640980 |
| 31 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.24501692 |
| 32 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.21382113 |
| 33 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.14153140 |
| 34 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.11793733 |
| 35 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.08005801 |
| 36 | Purine metabolism_Homo sapiens_hsa00230 | 1.07349872 |
| 37 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.04322964 |
| 38 | RNA transport_Homo sapiens_hsa03013 | 1.03832653 |
| 39 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.01904867 |
| 40 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.99633643 |
| 41 | Base excision repair_Homo sapiens_hsa03410 | 0.92110478 |
| 42 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.88660458 |
| 43 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.87810092 |
| 44 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.85746688 |
| 45 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.84723751 |
| 46 | Basal transcription factors_Homo sapiens_hsa03022 | 0.83144282 |
| 47 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.78835136 |
| 48 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.77898323 |
| 49 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.75777216 |
| 50 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.74480517 |
| 51 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.71594661 |
| 52 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.70507122 |
| 53 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.69044848 |
| 54 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.67403607 |
| 55 | Peroxisome_Homo sapiens_hsa04146 | 0.65910458 |
| 56 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.64297717 |
| 57 | Olfactory transduction_Homo sapiens_hsa04740 | 0.63154641 |
| 58 | Metabolic pathways_Homo sapiens_hsa01100 | 0.60606548 |
| 59 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.57492353 |
| 60 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.56547370 |
| 61 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.52772335 |
| 62 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.51689468 |
| 63 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.51180026 |
| 64 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.50705165 |
| 65 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.50651715 |
| 66 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.50300827 |
| 67 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.48587482 |
| 68 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.47144908 |
| 69 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.44920878 |
| 70 | Measles_Homo sapiens_hsa05162 | 0.42637364 |
| 71 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.41721566 |
| 72 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.41683448 |
| 73 | Retinol metabolism_Homo sapiens_hsa00830 | 0.40982659 |
| 74 | Taste transduction_Homo sapiens_hsa04742 | 0.40347882 |
| 75 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.39990475 |
| 76 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.39343266 |
| 77 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.37313372 |
| 78 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.37055130 |
| 79 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.36583966 |
| 80 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.35223891 |
| 81 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.32355043 |
| 82 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.31243378 |
| 83 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.30929117 |
| 84 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.30494317 |
| 85 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.30013371 |
| 86 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.29097912 |
| 87 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.27948434 |
| 88 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.26164041 |
| 89 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.25877586 |
| 90 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.23110109 |
| 91 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.22872679 |
| 92 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.22445641 |
| 93 | Mineral absorption_Homo sapiens_hsa04978 | 0.22301865 |
| 94 | Morphine addiction_Homo sapiens_hsa05032 | 0.22027984 |
| 95 | Viral myocarditis_Homo sapiens_hsa05416 | 0.21610559 |
| 96 | Nicotine addiction_Homo sapiens_hsa05033 | 0.18977498 |
| 97 | Malaria_Homo sapiens_hsa05144 | 0.16324324 |
| 98 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.15149281 |
| 99 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.14206038 |
| 100 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.13813101 |

