HNRNPA1P26

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1rRNA modification (GO:0000154)5.02511314
2ATP synthesis coupled proton transport (GO:0015986)4.89081188
3energy coupled proton transport, down electrochemical gradient (GO:0015985)4.89081188
4establishment of protein localization to mitochondrial membrane (GO:0090151)4.86674359
5mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.83373706
6IMP biosynthetic process (GO:0006188)4.70357902
7exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 4.39554561
8nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)4.39215602
9DNA deamination (GO:0045006)4.35504717
10rRNA methylation (GO:0031167)4.34687255
11negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.23463944
12proteasome assembly (GO:0043248)4.19975302
13water-soluble vitamin biosynthetic process (GO:0042364)4.02813501
14positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.99718929
15chaperone-mediated protein transport (GO:0072321)3.99148179
16regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.96441277
17DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.94827064
18signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.94453366
19signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.94453366
20signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.94453366
21IMP metabolic process (GO:0046040)3.92875204
22signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.85703359
23intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.85703359
24regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.84343715
25ribosome assembly (GO:0042255)3.81726252
26regulation of cellular amino acid metabolic process (GO:0006521)3.81549688
27signal transduction involved in DNA integrity checkpoint (GO:0072401)3.80978998
28signal transduction involved in DNA damage checkpoint (GO:0072422)3.80978998
29signal transduction involved in cell cycle checkpoint (GO:0072395)3.79495250
30cullin deneddylation (GO:0010388)3.79289034
31ribosomal large subunit biogenesis (GO:0042273)3.78734864
32negative regulation of ligase activity (GO:0051352)3.77581299
33negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.77581299
34establishment of integrated proviral latency (GO:0075713)3.72744219
35DNA strand elongation involved in DNA replication (GO:0006271)3.71712084
36anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.67262710
37pseudouridine synthesis (GO:0001522)3.64638977
38inner mitochondrial membrane organization (GO:0007007)3.63387896
39DNA catabolic process, exonucleolytic (GO:0000738)3.57776908
40protein deneddylation (GO:0000338)3.57537712
41DNA damage response, detection of DNA damage (GO:0042769)3.47233076
42folic acid-containing compound biosynthetic process (GO:0009396)3.46595348
43DNA strand elongation (GO:0022616)3.46165029
44DNA double-strand break processing (GO:0000729)3.44057038
45GTP biosynthetic process (GO:0006183)3.37907554
46purine nucleobase biosynthetic process (GO:0009113)3.32767469
47positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.30691569
48telomere maintenance via semi-conservative replication (GO:0032201)3.24181896
49positive regulation of ligase activity (GO:0051351)3.24085838
50tRNA aminoacylation for protein translation (GO:0006418)3.24005856
51spliceosomal snRNP assembly (GO:0000387)3.21033024
52tRNA processing (GO:0008033)3.20263443
53amino acid activation (GO:0043038)3.19905420
54tRNA aminoacylation (GO:0043039)3.19905420
55respiratory chain complex IV assembly (GO:0008535)3.19372256
56protein neddylation (GO:0045116)3.17818125
57guanosine-containing compound biosynthetic process (GO:1901070)3.13469607
58RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.11342878
59tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.11342878
60establishment of viral latency (GO:0019043)3.10695749
61tRNA metabolic process (GO:0006399)3.09089530
62transcription elongation from RNA polymerase I promoter (GO:0006362)3.07866548
63nucleobase biosynthetic process (GO:0046112)3.06412327
64termination of RNA polymerase I transcription (GO:0006363)3.04918857
65ribosomal small subunit assembly (GO:0000028)3.03717073
667-methylguanosine mRNA capping (GO:0006370)3.01842020
67purine nucleoside triphosphate biosynthetic process (GO:0009145)3.01305736
68transcription elongation from RNA polymerase III promoter (GO:0006385)3.00624800
69termination of RNA polymerase III transcription (GO:0006386)3.00624800
70DNA damage response, signal transduction by p53 class mediator (GO:0030330)3.00103523
71tRNA modification (GO:0006400)2.99704310
72UTP biosynthetic process (GO:0006228)2.99492569
73chromatin remodeling at centromere (GO:0031055)2.98225699
74purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.97715288
75maturation of SSU-rRNA (GO:0030490)2.96787218
76rRNA processing (GO:0006364)2.96504023
77GMP metabolic process (GO:0046037)2.93844554
78RNA capping (GO:0036260)2.93795605
797-methylguanosine RNA capping (GO:0009452)2.93795605
80CTP biosynthetic process (GO:0006241)2.93372982
81CTP metabolic process (GO:0046036)2.93372982
82antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.93215168
83purine-containing compound salvage (GO:0043101)2.93070821
84positive regulation of cell cycle arrest (GO:0071158)2.92985733
85pteridine-containing compound biosynthetic process (GO:0042559)2.91852788
86telomere maintenance via telomere lengthening (GO:0010833)2.89775733
87protein K6-linked ubiquitination (GO:0085020)2.89074241
88behavioral response to nicotine (GO:0035095)2.88341762
89regulation of cellular amine metabolic process (GO:0033238)2.87142967
90regulation of ubiquitin-protein transferase activity (GO:0051438)2.86718565
91rRNA metabolic process (GO:0016072)2.86234999
92replication fork processing (GO:0031297)2.86037922
93ATP biosynthetic process (GO:0006754)2.85022994
94translation (GO:0006412)2.84616417
95regulation of nuclear cell cycle DNA replication (GO:0033262)2.84136628
96UTP metabolic process (GO:0046051)2.83982018
97DNA demethylation (GO:0080111)2.83939255
98protein complex biogenesis (GO:0070271)2.83572335
99regulation of ligase activity (GO:0051340)2.83155420
100negative regulation of protein ubiquitination (GO:0031397)2.82140630

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.81587283
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.74508234
3GABP_17652178_ChIP-ChIP_JURKAT_Human4.59309574
4EST1_17652178_ChIP-ChIP_JURKAT_Human4.09168735
5JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.49933769
6SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.32326526
7MYC_18555785_ChIP-Seq_MESCs_Mouse3.30953294
8ETS1_20019798_ChIP-Seq_JURKAT_Human3.29104706
9HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.23449103
10NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.17295661
11E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.08161798
12ELF1_17652178_ChIP-ChIP_JURKAT_Human2.94948579
13E2F4_17652178_ChIP-ChIP_JURKAT_Human2.94788344
14VDR_23849224_ChIP-Seq_CD4+_Human2.90858253
15MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.79789588
16CREB1_15753290_ChIP-ChIP_HEK293T_Human2.79406740
17CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.78572531
18ELK1_19687146_ChIP-ChIP_HELA_Human2.73395214
19FOXP3_21729870_ChIP-Seq_TREG_Human2.50038537
20HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.39919662
21EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.26248017
22MYC_18358816_ChIP-ChIP_MESCs_Mouse2.26175863
23MYC_19030024_ChIP-ChIP_MESCs_Mouse2.19788299
24DCP1A_22483619_ChIP-Seq_HELA_Human2.10727240
25HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.09758892
26CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.07324982
27FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.06757841
28ZNF274_21170338_ChIP-Seq_K562_Hela2.04936055
29SRF_21415370_ChIP-Seq_HL-1_Mouse2.04678596
30FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.98122579
31THAP11_20581084_ChIP-Seq_MESCs_Mouse1.94061012
32GABP_19822575_ChIP-Seq_HepG2_Human1.93553883
33PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.90159936
34TTF2_22483619_ChIP-Seq_HELA_Human1.87938418
35PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.85933458
36VDR_22108803_ChIP-Seq_LS180_Human1.85565440
37MYC_19079543_ChIP-ChIP_MESCs_Mouse1.85326665
38E2F1_18555785_ChIP-Seq_MESCs_Mouse1.79907568
39MYC_18940864_ChIP-ChIP_HL60_Human1.78479961
40HOXB4_20404135_ChIP-ChIP_EML_Mouse1.75447023
41YY1_21170310_ChIP-Seq_MESCs_Mouse1.75147622
42ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.66611718
43NELFA_20434984_ChIP-Seq_ESCs_Mouse1.66511879
44CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.66031603
45XRN2_22483619_ChIP-Seq_HELA_Human1.63470004
46YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.62589451
47PADI4_21655091_ChIP-ChIP_MCF-7_Human1.56356188
48MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.51312050
49IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.47033018
50IGF1R_20145208_ChIP-Seq_DFB_Human1.46682532
51EWS_26573619_Chip-Seq_HEK293_Human1.44996335
52ELK1_22589737_ChIP-Seq_MCF10A_Human1.44994264
53FLI1_27457419_Chip-Seq_LIVER_Mouse1.44280495
54NOTCH1_21737748_ChIP-Seq_TLL_Human1.33221226
55IRF1_19129219_ChIP-ChIP_H3396_Human1.33142667
56SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.27554881
57FUS_26573619_Chip-Seq_HEK293_Human1.23571945
58E2F1_21310950_ChIP-Seq_MCF-7_Human1.21963207
59POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.15044683
60CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.14380068
61TP53_22573176_ChIP-Seq_HFKS_Human1.14215456
62SALL1_21062744_ChIP-ChIP_HESCs_Human1.14120914
63FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.14083953
64KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.13523288
65PCGF2_27294783_Chip-Seq_ESCs_Mouse1.13334084
66ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.10072607
67MYCN_18555785_ChIP-Seq_MESCs_Mouse1.09084929
68HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.08836689
69AR_21909140_ChIP-Seq_LNCAP_Human1.07991686
70CIITA_25753668_ChIP-Seq_RAJI_Human1.07976345
71SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.02275945
72POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.02202717
73PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.97264442
74POU5F1_16153702_ChIP-ChIP_HESCs_Human0.95144095
75CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.91300138
76TAF15_26573619_Chip-Seq_HEK293_Human0.91101030
77NANOG_16153702_ChIP-ChIP_HESCs_Human0.91026030
78EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.90279401
79EGR1_23403033_ChIP-Seq_LIVER_Mouse0.89836224
80KDM5A_27292631_Chip-Seq_BREAST_Human0.88527869
81E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.88180662
82FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.85688077
83FOXM1_23109430_ChIP-Seq_U2OS_Human0.83942799
84GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.82809052
85SOX2_16153702_ChIP-ChIP_HESCs_Human0.82756289
86FOXA1_25329375_ChIP-Seq_VCAP_Human0.81480303
87FOXA1_27270436_Chip-Seq_PROSTATE_Human0.81480303
88P300_19829295_ChIP-Seq_ESCs_Human0.81169138
89ERG_20887958_ChIP-Seq_HPC-7_Mouse0.80494683
90AR_20517297_ChIP-Seq_VCAP_Human0.80355865
91TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.80001665
92FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.78522558
93AUTS2_25519132_ChIP-Seq_293T-REX_Human0.77915497
94PCGF2_27294783_Chip-Seq_NPCs_Mouse0.77090433
95DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.76995853
96RBPJ_22232070_ChIP-Seq_NCS_Mouse0.74928555
97MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.74120697
98SOX17_20123909_ChIP-Seq_XEN_Mouse0.73755312
99NCOR_22424771_ChIP-Seq_293T_Human0.73112544
100CTBP2_25329375_ChIP-Seq_LNCAP_Human0.72847832

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008058_abnormal_DNA_repair4.57411833
2MP0002102_abnormal_ear_morphology3.75705544
3MP0010094_abnormal_chromosome_stability3.70644046
4MP0008877_abnormal_DNA_methylation3.57832008
5MP0003693_abnormal_embryo_hatching3.51980695
6MP0006292_abnormal_olfactory_placode3.34827402
7MP0002254_reproductive_system_inflammat2.95180406
8MP0003111_abnormal_nucleus_morphology2.88514650
9MP0004147_increased_porphyrin_level2.76736528
10MP0004957_abnormal_blastocyst_morpholog2.72369006
11MP0003786_premature_aging2.33316903
12MP0008789_abnormal_olfactory_epithelium2.27579085
13MP0008057_abnormal_DNA_replication2.19299116
14MP0005394_taste/olfaction_phenotype2.09889392
15MP0005499_abnormal_olfactory_system2.09889392
16MP0006072_abnormal_retinal_apoptosis2.07579488
17MP0005084_abnormal_gallbladder_morpholo2.07286917
18MP0003718_maternal_effect2.06298979
19MP0003077_abnormal_cell_cycle1.98068878
20MP0005671_abnormal_response_to1.83884854
21MP0002736_abnormal_nociception_after1.71888753
22MP0004145_abnormal_muscle_electrophysio1.67102392
23MP0001529_abnormal_vocalization1.65780218
24MP0008872_abnormal_physiological_respon1.64797761
25MP0009697_abnormal_copulation1.56378275
26MP0000372_irregular_coat_pigmentation1.50382386
27MP0001293_anophthalmia1.48540579
28MP0005551_abnormal_eye_electrophysiolog1.47448757
29MP0002876_abnormal_thyroid_physiology1.46818205
30MP0008932_abnormal_embryonic_tissue1.40222247
31MP0006036_abnormal_mitochondrial_physio1.39091897
32MP0002837_dystrophic_cardiac_calcinosis1.39044590
33MP0002938_white_spotting1.37898597
34MP0003763_abnormal_thymus_physiology1.37165651
35MP0008875_abnormal_xenobiotic_pharmacok1.36180772
36MP0003567_abnormal_fetal_cardiomyocyte1.35352603
37MP0002210_abnormal_sex_determination1.30364194
38MP0005253_abnormal_eye_physiology1.26761128
39MP0006035_abnormal_mitochondrial_morpho1.24894899
40MP0003806_abnormal_nucleotide_metabolis1.24108692
41MP0001727_abnormal_embryo_implantation1.16460409
42MP0001929_abnormal_gametogenesis1.16198824
43MP0001873_stomach_inflammation1.14276996
44MP0001984_abnormal_olfaction1.09867449
45MP0001835_abnormal_antigen_presentation1.09797469
46MP0003119_abnormal_digestive_system1.08224696
47MP0009785_altered_susceptibility_to1.06152413
48MP0002090_abnormal_vision1.06148255
49MP0003186_abnormal_redox_activity1.05274071
50MP0005645_abnormal_hypothalamus_physiol1.03220083
51MP0001145_abnormal_male_reproductive1.02607366
52MP0003195_calcinosis1.02106626
53MP0008995_early_reproductive_senescence1.02102125
54MP0000653_abnormal_sex_gland0.99075248
55MP0001764_abnormal_homeostasis0.98711012
56MP0008007_abnormal_cellular_replicative0.98548580
57MP0002277_abnormal_respiratory_mucosa0.95520540
58MP0001346_abnormal_lacrimal_gland0.93998906
59MP0001188_hyperpigmentation0.93965527
60MP0004885_abnormal_endolymph0.92736764
61MP0005647_abnormal_sex_gland0.92160342
62MP0002751_abnormal_autonomic_nervous0.90574541
63MP0001968_abnormal_touch/_nociception0.87583415
64MP0000490_abnormal_crypts_of0.86281898
65MP0005167_abnormal_blood-brain_barrier0.85960874
66MP0005332_abnormal_amino_acid0.85324266
67MP0009333_abnormal_splenocyte_physiolog0.84274269
68MP0002653_abnormal_ependyma_morphology0.82826138
69MP0000427_abnormal_hair_cycle0.81627185
70MP0001119_abnormal_female_reproductive0.81120447
71MP0002160_abnormal_reproductive_system0.80544153
72MP0003938_abnormal_ear_development0.80164080
73MP0003698_abnormal_male_reproductive0.79340883
74MP0000358_abnormal_cell_content/0.77947777
75MP0005377_hearing/vestibular/ear_phenot0.75443221
76MP0003878_abnormal_ear_physiology0.75443221
77MP0005379_endocrine/exocrine_gland_phen0.74385992
78MP0003937_abnormal_limbs/digits/tail_de0.73447576
79MP0005410_abnormal_fertilization0.73319917
80MP0000647_abnormal_sebaceous_gland0.72255100
81MP0001853_heart_inflammation0.71913864
82MP0010386_abnormal_urinary_bladder0.71449467
83MP0009764_decreased_sensitivity_to0.69995503
84MP0000465_gastrointestinal_hemorrhage0.69820047
85MP0002006_tumorigenesis0.69684714
86MP0000685_abnormal_immune_system0.66274590
87MP0009379_abnormal_foot_pigmentation0.65675437
88MP0003011_delayed_dark_adaptation0.63675020
89MP0001905_abnormal_dopamine_level0.62800710
90MP0001348_abnormal_lacrimal_gland0.62744361
91MP0004215_abnormal_myocardial_fiber0.61839592
92MP0005365_abnormal_bile_salt0.61120569
93MP0000313_abnormal_cell_death0.61037229
94MP0006276_abnormal_autonomic_nervous0.60944652
95MP0005389_reproductive_system_phenotype0.60180842
96MP0002148_abnormal_hypersensitivity_rea0.60162092
97MP0000049_abnormal_middle_ear0.59883363
98MP0005636_abnormal_mineral_homeostasis0.58920488
99MP0004742_abnormal_vestibular_system0.58853212
100MP0002111_abnormal_tail_morphology0.58563783

Predicted human phenotypes

RankGene SetZ-score
1Testicular atrophy (HP:0000029)4.30235011
2Lipid accumulation in hepatocytes (HP:0006561)4.19013216
3Increased hepatocellular lipid droplets (HP:0006565)4.10833151
4Mitochondrial inheritance (HP:0001427)3.76802548
5Acute necrotizing encephalopathy (HP:0006965)3.73027404
63-Methylglutaconic aciduria (HP:0003535)3.66313301
7Increased CSF lactate (HP:0002490)3.52508942
8Acute encephalopathy (HP:0006846)3.24891991
9Abnormal mitochondria in muscle tissue (HP:0008316)3.24764489
10Methylmalonic acidemia (HP:0002912)3.22055780
11Progressive macrocephaly (HP:0004481)2.98619472
12Reticulocytopenia (HP:0001896)2.93131463
13Renal Fanconi syndrome (HP:0001994)2.92646855
14Microvesicular hepatic steatosis (HP:0001414)2.91455478
15Hepatocellular necrosis (HP:0001404)2.91294092
16Respiratory difficulties (HP:0002880)2.91261921
17Opisthotonus (HP:0002179)2.89420384
18Meckel diverticulum (HP:0002245)2.80550057
19Chromosomal breakage induced by crosslinking agents (HP:0003221)2.77055610
20Increased serum lactate (HP:0002151)2.75031792
21Abnormality of the ileum (HP:0001549)2.68196353
22Chromsome breakage (HP:0040012)2.66469890
23Cerebral edema (HP:0002181)2.65425229
24Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.65272164
25Abnormality of alanine metabolism (HP:0010916)2.65272164
26Hyperalaninemia (HP:0003348)2.65272164
27Delayed CNS myelination (HP:0002188)2.62781357
28Hepatic necrosis (HP:0002605)2.60612040
29Methylmalonic aciduria (HP:0012120)2.53347692
30Type I transferrin isoform profile (HP:0003642)2.52089476
31Prostate neoplasm (HP:0100787)2.49812951
32Abnormality of the labia minora (HP:0012880)2.47020051
33Optic disc pallor (HP:0000543)2.44057917
34Increased serum pyruvate (HP:0003542)2.43181348
35Aplasia/Hypoplasia of the uvula (HP:0010293)2.42970643
36Lactic acidosis (HP:0003128)2.39331713
37Abnormality of the preputium (HP:0100587)2.38595079
38Pancytopenia (HP:0001876)2.38438113
39Colon cancer (HP:0003003)2.36907788
40Exertional dyspnea (HP:0002875)2.35373995
41Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.33890530
42Visual hallucinations (HP:0002367)2.32513228
43Parakeratosis (HP:0001036)2.29237841
44Abnormal glycosylation (HP:0012345)2.28141435
45Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.28141435
46Abnormal protein N-linked glycosylation (HP:0012347)2.28141435
47Abnormal protein glycosylation (HP:0012346)2.28141435
48Dyschromatopsia (HP:0007641)2.27106634
49Cerebral hypomyelination (HP:0006808)2.25577311
50Abolished electroretinogram (ERG) (HP:0000550)2.24824470
51Short tibia (HP:0005736)2.23275520
52Abnormality of the vitamin B12 metabolism (HP:0004341)2.21701017
53Abnormality of chromosome stability (HP:0003220)2.20887466
54Congenital, generalized hypertrichosis (HP:0004540)2.20794942
55Abnormality of midbrain morphology (HP:0002418)2.17399150
56Molar tooth sign on MRI (HP:0002419)2.17399150
57Gout (HP:0001997)2.15871710
58Abnormality of glycolysis (HP:0004366)2.14865721
59Increased intramyocellular lipid droplets (HP:0012240)2.14589473
60Carpal bone hypoplasia (HP:0001498)2.14568812
61Megaloblastic anemia (HP:0001889)2.13422942
62Pendular nystagmus (HP:0012043)2.11313647
63Lethargy (HP:0001254)2.10480658
64Pancreatic cysts (HP:0001737)2.10025050
65Spastic diplegia (HP:0001264)2.09143780
66Oral leukoplakia (HP:0002745)2.06252143
67Abnormality of vitamin B metabolism (HP:0004340)2.03117273
68Congenital stationary night blindness (HP:0007642)2.02673974
69Clubbing of toes (HP:0100760)1.99704405
70Leukodystrophy (HP:0002415)1.99032389
71Increased muscle lipid content (HP:0009058)1.97667763
72Respiratory failure (HP:0002878)1.96947321
73Hypoplasia of the pons (HP:0012110)1.96838023
74Decreased activity of mitochondrial respiratory chain (HP:0008972)1.96072913
75Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.96072913
76Adrenal hypoplasia (HP:0000835)1.95503562
77Aplasia/Hypoplasia of the tibia (HP:0005772)1.95149349
78Lissencephaly (HP:0001339)1.95044763
79Macrocytic anemia (HP:0001972)1.94326744
80Duodenal stenosis (HP:0100867)1.94232740
81Small intestinal stenosis (HP:0012848)1.94232740
82Inability to walk (HP:0002540)1.91176553
83Nephronophthisis (HP:0000090)1.91164630
84Abnormality of the prostate (HP:0008775)1.90238771
85Duplicated collecting system (HP:0000081)1.89589795
86Abnormality of serum amino acid levels (HP:0003112)1.88085345
87Amniotic constriction ring (HP:0009775)1.88018846
88Abnormality of placental membranes (HP:0011409)1.88018846
89Thyroid-stimulating hormone excess (HP:0002925)1.86345247
90Supernumerary spleens (HP:0009799)1.86300885
91Abnormality of methionine metabolism (HP:0010901)1.85788010
92Aplasia/hypoplasia of the uterus (HP:0008684)1.85424496
93Abnormality of aspartate family amino acid metabolism (HP:0010899)1.85380308
94CNS hypomyelination (HP:0003429)1.82857436
95Retinal dysplasia (HP:0007973)1.82679586
96Triphalangeal thumb (HP:0001199)1.81965993
97IgG deficiency (HP:0004315)1.81790527
98Abnormality of the pons (HP:0007361)1.81152015
99Autoimmune thrombocytopenia (HP:0001973)1.80585314
100Sloping forehead (HP:0000340)1.80277025

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K24.27643432
2ZAK3.92515806
3VRK23.82506613
4NEK13.61888023
5MST43.45610870
6BUB13.28694868
7TSSK63.12364287
8TAF12.63640378
9PBK2.56718061
10NUAK12.43619351
11TXK2.42014010
12EIF2AK32.22757411
13EIF2AK12.08293362
14SRPK12.04808599
15CDC72.00651198
16VRK11.94768095
17TLK11.89745565
18PLK31.83744827
19ADRBK21.69916889
20BCKDK1.57194890
21STK161.53545553
22CDK191.49391305
23NME11.40901723
24TRIM281.39365736
25CSNK1G31.33268109
26CSNK1A1L1.32993921
27PLK41.32692993
28OXSR11.29277101
29PASK1.28365627
30TTK1.28287344
31STK38L1.21004837
32MKNK11.20697456
33CSNK1G11.19631486
34DYRK21.12955996
35EIF2AK21.12866314
36GRK11.09712668
37PLK11.06870743
38WNK31.02215392
39CSNK1G21.00527135
40CASK0.94675146
41ATR0.92716325
42DAPK10.89123243
43WEE10.89018129
44CCNB10.88971746
45TAOK10.88318528
46PDK20.87984589
47NME20.86141624
48WNK40.84580938
49AURKA0.83114205
50MAP4K10.81653044
51MAP3K40.79533531
52BCR0.79087946
53CHEK20.78120208
54AURKB0.76379617
55PLK20.70493225
56PAK40.69241725
57TGFBR10.61698541
58MAPKAPK50.59489090
59STK390.58253963
60ATM0.54541726
61DAPK30.50311303
62DAPK20.48923544
63SMG10.48449764
64CSNK2A10.47742331
65MAP2K70.47348220
66IKBKB0.44929597
67CSNK2A20.43275046
68CSNK1A10.42957095
69PHKG20.42549990
70PHKG10.42549990
71ERBB40.41111273
72BMPR1B0.40328191
73MKNK20.39778308
74IRAK40.38345088
75PNCK0.38326724
76CHEK10.37430665
77IKBKE0.37240943
78CDK70.37204039
79ALK0.36765327
80RPS6KA50.36551586
81RPS6KA40.35296686
82TIE10.35101196
83DYRK30.34351642
84TNIK0.33511678
85BRSK20.32134249
86FES0.27980257
87MAPK130.27506884
88STK100.25246415
89PRKCG0.23943834
90GRK50.23899971
91STK40.23864504
92CDK90.23569202
93ADRBK10.23200009
94WNK10.22878646
95PRKDC0.22873345
96TEC0.22441503
97IGF1R0.22398676
98EPHB20.21841421
99CSNK1E0.21383642
100MAP3K140.19893536

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030505.00238986
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.04688432
3DNA replication_Homo sapiens_hsa030302.92431251
4Oxidative phosphorylation_Homo sapiens_hsa001902.74784165
5Mismatch repair_Homo sapiens_hsa034302.71790932
6Ribosome_Homo sapiens_hsa030102.70130104
7RNA polymerase_Homo sapiens_hsa030202.56614081
8Non-homologous end-joining_Homo sapiens_hsa034502.54736518
9Protein export_Homo sapiens_hsa030602.53347988
10Homologous recombination_Homo sapiens_hsa034402.49677670
11Parkinsons disease_Homo sapiens_hsa050122.33522332
12Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.27747650
13Spliceosome_Homo sapiens_hsa030402.16074052
14One carbon pool by folate_Homo sapiens_hsa006702.09672250
15RNA degradation_Homo sapiens_hsa030182.06647494
16Basal transcription factors_Homo sapiens_hsa030221.96556035
17Fanconi anemia pathway_Homo sapiens_hsa034601.93809628
18Nucleotide excision repair_Homo sapiens_hsa034201.77644216
19Propanoate metabolism_Homo sapiens_hsa006401.76712153
20Base excision repair_Homo sapiens_hsa034101.75028902
21Pyrimidine metabolism_Homo sapiens_hsa002401.74068921
22RNA transport_Homo sapiens_hsa030131.71611515
23Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.70866408
24Huntingtons disease_Homo sapiens_hsa050161.69092155
25Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.44446129
26Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.40067233
27Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.36083971
28Purine metabolism_Homo sapiens_hsa002301.35814998
29Alzheimers disease_Homo sapiens_hsa050101.35127850
30Selenocompound metabolism_Homo sapiens_hsa004501.31675666
31Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.17401243
32Sulfur metabolism_Homo sapiens_hsa009201.15272277
33Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.14930822
34Cysteine and methionine metabolism_Homo sapiens_hsa002701.14379446
35Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.09520894
36Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.08057842
37Butanoate metabolism_Homo sapiens_hsa006501.07478067
38Fatty acid elongation_Homo sapiens_hsa000621.04727156
39Tryptophan metabolism_Homo sapiens_hsa003801.03593003
40Asthma_Homo sapiens_hsa053101.02956700
41Cyanoamino acid metabolism_Homo sapiens_hsa004601.00920202
42Type I diabetes mellitus_Homo sapiens_hsa049401.00755864
43Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.98208022
44Pyruvate metabolism_Homo sapiens_hsa006200.97221194
45Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.92476857
46Peroxisome_Homo sapiens_hsa041460.91452440
472-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.88596287
48Linoleic acid metabolism_Homo sapiens_hsa005910.88286744
49Steroid biosynthesis_Homo sapiens_hsa001000.87456231
50Phototransduction_Homo sapiens_hsa047440.86036460
51Cell cycle_Homo sapiens_hsa041100.85690588
52mRNA surveillance pathway_Homo sapiens_hsa030150.81023713
53alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.80644562
54Intestinal immune network for IgA production_Homo sapiens_hsa046720.76277868
55Cardiac muscle contraction_Homo sapiens_hsa042600.75850050
56Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.75532611
57Systemic lupus erythematosus_Homo sapiens_hsa053220.72032024
58Folate biosynthesis_Homo sapiens_hsa007900.71725192
59Caffeine metabolism_Homo sapiens_hsa002320.70327215
60Metabolic pathways_Homo sapiens_hsa011000.69629773
61Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.69270958
62Primary immunodeficiency_Homo sapiens_hsa053400.68483197
63Glutathione metabolism_Homo sapiens_hsa004800.65291383
64Allograft rejection_Homo sapiens_hsa053300.62476895
65Biosynthesis of amino acids_Homo sapiens_hsa012300.61770580
66Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.58463586
67Regulation of autophagy_Homo sapiens_hsa041400.57121480
68Ether lipid metabolism_Homo sapiens_hsa005650.56343031
69Pentose and glucuronate interconversions_Homo sapiens_hsa000400.55891765
70Autoimmune thyroid disease_Homo sapiens_hsa053200.55377250
71Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.54235270
72Carbon metabolism_Homo sapiens_hsa012000.52981813
73SNARE interactions in vesicular transport_Homo sapiens_hsa041300.51090405
74Fatty acid metabolism_Homo sapiens_hsa012120.49967510
75Sulfur relay system_Homo sapiens_hsa041220.48955251
76Vitamin B6 metabolism_Homo sapiens_hsa007500.48859692
77p53 signaling pathway_Homo sapiens_hsa041150.48126406
78Graft-versus-host disease_Homo sapiens_hsa053320.47387021
79Nitrogen metabolism_Homo sapiens_hsa009100.47077329
80Fatty acid degradation_Homo sapiens_hsa000710.47023631
81Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.46538608
82Fat digestion and absorption_Homo sapiens_hsa049750.46090667
83Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.43319859
84Drug metabolism - other enzymes_Homo sapiens_hsa009830.43184520
85Epstein-Barr virus infection_Homo sapiens_hsa051690.43150440
86Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.41634920
87beta-Alanine metabolism_Homo sapiens_hsa004100.39561608
88N-Glycan biosynthesis_Homo sapiens_hsa005100.39217849
89Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.37418604
90Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.37129529
91Arginine and proline metabolism_Homo sapiens_hsa003300.35731955
92Collecting duct acid secretion_Homo sapiens_hsa049660.33543308
93Maturity onset diabetes of the young_Homo sapiens_hsa049500.32284454
94Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.31117548
95Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.30670644
96Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.30323583
97Oocyte meiosis_Homo sapiens_hsa041140.29643612
98Antigen processing and presentation_Homo sapiens_hsa046120.29583626
99Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.28530843
100Retinol metabolism_Homo sapiens_hsa008300.28041716

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »