

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | desmosome organization (GO:0002934) | 7.54297660 |
| 2 | keratinocyte proliferation (GO:0043616) | 5.24705620 |
| 3 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 5.12358039 |
| 4 | keratinocyte development (GO:0003334) | 4.68155624 |
| 5 | establishment of skin barrier (GO:0061436) | 4.66561617 |
| 6 | gap junction assembly (GO:0016264) | 4.39791360 |
| 7 | ribosomal large subunit biogenesis (GO:0042273) | 4.35541770 |
| 8 | DNA deamination (GO:0045006) | 4.21832178 |
| 9 | ribosomal small subunit assembly (GO:0000028) | 4.15676063 |
| 10 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 4.15046915 |
| 11 | lateral sprouting from an epithelium (GO:0060601) | 3.96855780 |
| 12 | ribosome assembly (GO:0042255) | 3.95220633 |
| 13 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.89748332 |
| 14 | proteasome assembly (GO:0043248) | 3.88560574 |
| 15 | regulation of water loss via skin (GO:0033561) | 3.81261244 |
| 16 | negative regulation of keratinocyte proliferation (GO:0010839) | 3.78245700 |
| 17 | keratinization (GO:0031424) | 3.60482235 |
| 18 | sequestering of actin monomers (GO:0042989) | 3.60463873 |
| 19 | regulation of memory T cell differentiation (GO:0043380) | 3.57973302 |
| 20 | positive regulation of interleukin-17 production (GO:0032740) | 3.56028321 |
| 21 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.50183924 |
| 22 | molting cycle (GO:0042303) | 3.49540092 |
| 23 | hair cycle (GO:0042633) | 3.49540092 |
| 24 | nucleoside transmembrane transport (GO:1901642) | 3.44243002 |
| 25 | ribosome biogenesis (GO:0042254) | 3.42956398 |
| 26 | polarized epithelial cell differentiation (GO:0030859) | 3.39236806 |
| 27 | cornea development in camera-type eye (GO:0061303) | 3.39133526 |
| 28 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.38923597 |
| 29 | nucleoside transport (GO:0015858) | 3.36183952 |
| 30 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.34923401 |
| 31 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 3.34364654 |
| 32 | maturation of SSU-rRNA (GO:0030490) | 3.30564566 |
| 33 | regulation of keratinocyte proliferation (GO:0010837) | 3.30148709 |
| 34 | intermediate filament organization (GO:0045109) | 3.26872144 |
| 35 | viral transcription (GO:0019083) | 3.20504500 |
| 36 | translational termination (GO:0006415) | 3.20358161 |
| 37 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.19283049 |
| 38 | cotranslational protein targeting to membrane (GO:0006613) | 3.13128594 |
| 39 | protein targeting to ER (GO:0045047) | 3.11046648 |
| 40 | negative regulation of cell aging (GO:0090344) | 3.07555852 |
| 41 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.04413357 |
| 42 | translational elongation (GO:0006414) | 3.04157009 |
| 43 | positive regulation of hair follicle development (GO:0051798) | 3.02544332 |
| 44 | positive regulation of hair cycle (GO:0042635) | 3.02544332 |
| 45 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.02489910 |
| 46 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 3.02338004 |
| 47 | epidermis development (GO:0008544) | 3.02070546 |
| 48 | ribosomal small subunit biogenesis (GO:0042274) | 3.01498996 |
| 49 | protein localization to endoplasmic reticulum (GO:0070972) | 2.98294811 |
| 50 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.95683747 |
| 51 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.95598965 |
| 52 | rRNA processing (GO:0006364) | 2.93938297 |
| 53 | keratinocyte differentiation (GO:0030216) | 2.93456747 |
| 54 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.93259006 |
| 55 | translational initiation (GO:0006413) | 2.92808322 |
| 56 | protein neddylation (GO:0045116) | 2.92336569 |
| 57 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.92179495 |
| 58 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.90000862 |
| 59 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.90000862 |
| 60 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.90000862 |
| 61 | rRNA metabolic process (GO:0016072) | 2.87626069 |
| 62 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.87030409 |
| 63 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.87030409 |
| 64 | behavioral response to nicotine (GO:0035095) | 2.85746929 |
| 65 | organ formation (GO:0048645) | 2.82875397 |
| 66 | formation of translation preinitiation complex (GO:0001731) | 2.82762644 |
| 67 | rRNA modification (GO:0000154) | 2.79819522 |
| 68 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.77642425 |
| 69 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.77642425 |
| 70 | translation (GO:0006412) | 2.76913642 |
| 71 | negative regulation of acute inflammatory response (GO:0002674) | 2.76644372 |
| 72 | cellular component biogenesis (GO:0044085) | 2.76449944 |
| 73 | regulation of tyrosine phosphorylation of Stat1 protein (GO:0042510) | 2.75480926 |
| 74 | AMP metabolic process (GO:0046033) | 2.74504889 |
| 75 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.74439304 |
| 76 | cell-substrate junction assembly (GO:0007044) | 2.73103758 |
| 77 | protein autoprocessing (GO:0016540) | 2.72314117 |
| 78 | diterpenoid biosynthetic process (GO:0016102) | 2.71738670 |
| 79 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.70289017 |
| 80 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.68751008 |
| 81 | GMP metabolic process (GO:0046037) | 2.67471595 |
| 82 | regulation of activation of Janus kinase activity (GO:0010533) | 2.65099850 |
| 83 | negative regulation of ligase activity (GO:0051352) | 2.64850599 |
| 84 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.64850599 |
| 85 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.63687487 |
| 86 | ATP synthesis coupled proton transport (GO:0015986) | 2.63687487 |
| 87 | drug transmembrane transport (GO:0006855) | 2.62362823 |
| 88 | type B pancreatic cell proliferation (GO:0044342) | 2.62191604 |
| 89 | DNA double-strand break processing (GO:0000729) | 2.62008815 |
| 90 | hepatocyte differentiation (GO:0070365) | 2.61101224 |
| 91 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.60634146 |
| 92 | polyketide metabolic process (GO:0030638) | 2.59939110 |
| 93 | doxorubicin metabolic process (GO:0044598) | 2.59939110 |
| 94 | daunorubicin metabolic process (GO:0044597) | 2.59939110 |
| 95 | terpenoid biosynthetic process (GO:0016114) | 2.57312066 |
| 96 | base-excision repair, AP site formation (GO:0006285) | 2.56869481 |
| 97 | positive regulation of T-helper 1 type immune response (GO:0002827) | 2.54306043 |
| 98 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.53240777 |
| 99 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.53121441 |
| 100 | hemidesmosome assembly (GO:0031581) | 10.2005470 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.80128745 |
| 2 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 3.62432691 |
| 3 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 3.30880011 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.28959730 |
| 5 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.02903782 |
| 6 | ZNF263_19887448_ChIP-Seq_K562_Human | 3.01127873 |
| 7 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.80331974 |
| 8 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.64271624 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.54511753 |
| 10 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.45197972 |
| 11 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.22583007 |
| 12 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.14844476 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.11357071 |
| 14 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.02965357 |
| 15 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.02936775 |
| 16 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 10.0298707 |
| 17 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.97564889 |
| 18 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.95266810 |
| 19 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.92235472 |
| 20 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.92235472 |
| 21 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.85670591 |
| 22 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.81961792 |
| 23 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.81551170 |
| 24 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.76706385 |
| 25 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.73724577 |
| 26 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.68352799 |
| 27 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.64687158 |
| 28 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.59791260 |
| 29 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.57063309 |
| 30 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.55734667 |
| 31 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.55674311 |
| 32 | EWS_26573619_Chip-Seq_HEK293_Human | 1.55076522 |
| 33 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.53975208 |
| 34 | VDR_22108803_ChIP-Seq_LS180_Human | 1.48309388 |
| 35 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.46540964 |
| 36 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.45387056 |
| 37 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.43325858 |
| 38 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.42524028 |
| 39 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.39652927 |
| 40 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.38769872 |
| 41 | FUS_26573619_Chip-Seq_HEK293_Human | 1.37225980 |
| 42 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.36073158 |
| 43 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.34717598 |
| 44 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.34642697 |
| 45 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.34383691 |
| 46 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.33562653 |
| 47 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.33385806 |
| 48 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.29265415 |
| 49 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.27065044 |
| 50 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.25566472 |
| 51 | TP63_23658742_ChIP-Seq_EP156T_Human | 1.24363210 |
| 52 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.23226261 |
| 53 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.22538565 |
| 54 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.17811478 |
| 55 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.17413238 |
| 56 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.14334507 |
| 57 | CJUN_26792858_Chip-Seq_BT549_Human | 1.07997038 |
| 58 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.07820795 |
| 59 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.06920781 |
| 60 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.06433323 |
| 61 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.04675730 |
| 62 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.04655156 |
| 63 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.04341613 |
| 64 | ELF5_23300383_ChIP-Seq_T47D_Human | 1.04336915 |
| 65 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.02974813 |
| 66 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.02974813 |
| 67 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.01810489 |
| 68 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.00104695 |
| 69 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.98184452 |
| 70 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.97109366 |
| 71 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.96298758 |
| 72 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.92796356 |
| 73 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.92796356 |
| 74 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.92407836 |
| 75 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 0.90740288 |
| 76 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 0.90116706 |
| 77 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.89753645 |
| 78 | AR_20517297_ChIP-Seq_VCAP_Human | 0.89626440 |
| 79 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.86581971 |
| 80 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.85502555 |
| 81 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.85378694 |
| 82 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.84645828 |
| 83 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.84261196 |
| 84 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.84220358 |
| 85 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.84193421 |
| 86 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.83806792 |
| 87 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.83748799 |
| 88 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.83151128 |
| 89 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.82791448 |
| 90 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.82525984 |
| 91 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.82525984 |
| 92 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.80720538 |
| 93 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.79828235 |
| 94 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.78967853 |
| 95 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.78657866 |
| 96 | GATA1_22025678_ChIP-Seq_K562_Human | 0.77019372 |
| 97 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.76633704 |
| 98 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.75558719 |
| 99 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.75084916 |
| 100 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.74338736 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000579_abnormal_nail_morphology | 6.39452213 |
| 2 | MP0000566_synostosis | 4.58522800 |
| 3 | MP0010234_abnormal_vibrissa_follicle | 3.86735349 |
| 4 | MP0002796_impaired_skin_barrier | 3.51574828 |
| 5 | MP0002234_abnormal_pharynx_morphology | 3.15201344 |
| 6 | MP0009053_abnormal_anal_canal | 2.77233358 |
| 7 | MP0000762_abnormal_tongue_morphology | 2.75402406 |
| 8 | MP0000467_abnormal_esophagus_morphology | 2.75352321 |
| 9 | MP0010678_abnormal_skin_adnexa | 2.73872390 |
| 10 | MP0000383_abnormal_hair_follicle | 2.51640122 |
| 11 | MP0003806_abnormal_nucleotide_metabolis | 2.50738308 |
| 12 | MP0001216_abnormal_epidermal_layer | 2.47521639 |
| 13 | MP0008875_abnormal_xenobiotic_pharmacok | 2.42524279 |
| 14 | MP0005501_abnormal_skin_physiology | 2.38357411 |
| 15 | MP0002098_abnormal_vibrissa_morphology | 2.26591218 |
| 16 | MP0005275_abnormal_skin_tensile | 2.20174823 |
| 17 | MP0003941_abnormal_skin_development | 2.17974038 |
| 18 | MP0005360_urolithiasis | 2.13958261 |
| 19 | MP0002060_abnormal_skin_morphology | 2.09998263 |
| 20 | MP0004957_abnormal_blastocyst_morpholog | 2.01555983 |
| 21 | MP0009697_abnormal_copulation | 1.97010986 |
| 22 | MP0010771_integument_phenotype | 1.94808008 |
| 23 | MP0000537_abnormal_urethra_morphology | 1.94168452 |
| 24 | MP0001348_abnormal_lacrimal_gland | 1.78759440 |
| 25 | MP0004782_abnormal_surfactant_physiolog | 1.75673003 |
| 26 | MP0001661_extended_life_span | 1.73033221 |
| 27 | MP0003693_abnormal_embryo_hatching | 1.65776807 |
| 28 | MP0000377_abnormal_hair_follicle | 1.63232930 |
| 29 | MP0000647_abnormal_sebaceous_gland | 1.60377595 |
| 30 | MP0003950_abnormal_plasma_membrane | 1.59174486 |
| 31 | MP0008872_abnormal_physiological_respon | 1.52422133 |
| 32 | MP0003453_abnormal_keratinocyte_physiol | 1.51485843 |
| 33 | MP0003718_maternal_effect | 1.51081631 |
| 34 | MP0003786_premature_aging | 1.49799536 |
| 35 | MP0008058_abnormal_DNA_repair | 1.49629051 |
| 36 | MP0002102_abnormal_ear_morphology | 1.49112750 |
| 37 | MP0005085_abnormal_gallbladder_physiolo | 1.45903304 |
| 38 | MP0005451_abnormal_body_composition | 1.44971280 |
| 39 | MP0005023_abnormal_wound_healing | 1.42060128 |
| 40 | MP0005257_abnormal_intraocular_pressure | 1.34224937 |
| 41 | MP0010030_abnormal_orbit_morphology | 1.33092785 |
| 42 | MP0009379_abnormal_foot_pigmentation | 1.30340944 |
| 43 | MP0004381_abnormal_hair_follicle | 1.25888815 |
| 44 | MP0002282_abnormal_trachea_morphology | 1.25202088 |
| 45 | MP0000627_abnormal_mammary_gland | 1.23865755 |
| 46 | MP0004019_abnormal_vitamin_homeostasis | 1.23731529 |
| 47 | MP0006072_abnormal_retinal_apoptosis | 1.22058021 |
| 48 | MP0002160_abnormal_reproductive_system | 1.19441406 |
| 49 | MP0005389_reproductive_system_phenotype | 1.14941479 |
| 50 | MP0000372_irregular_coat_pigmentation | 1.14808859 |
| 51 | MP0003252_abnormal_bile_duct | 1.13725423 |
| 52 | MP0002876_abnormal_thyroid_physiology | 1.11509580 |
| 53 | MP0000427_abnormal_hair_cycle | 1.11079878 |
| 54 | MP0010368_abnormal_lymphatic_system | 1.07017560 |
| 55 | MP0004272_abnormal_basement_membrane | 1.06088811 |
| 56 | MP0008877_abnormal_DNA_methylation | 1.04598020 |
| 57 | MP0003937_abnormal_limbs/digits/tail_de | 1.02396207 |
| 58 | MP0003638_abnormal_response/metabolism_ | 1.01380187 |
| 59 | MP0003566_abnormal_cell_adhesion | 0.99619061 |
| 60 | MP0001984_abnormal_olfaction | 0.95172794 |
| 61 | MP0001919_abnormal_reproductive_system | 0.92620272 |
| 62 | MP0003315_abnormal_perineum_morphology | 0.89796798 |
| 63 | MP0001191_abnormal_skin_condition | 0.89670544 |
| 64 | MP0003936_abnormal_reproductive_system | 0.86372826 |
| 65 | MP0003755_abnormal_palate_morphology | 0.85046464 |
| 66 | MP0001764_abnormal_homeostasis | 0.82556932 |
| 67 | MP0009780_abnormal_chondrocyte_physiolo | 0.81962180 |
| 68 | MP0010352_gastrointestinal_tract_polyps | 0.81783789 |
| 69 | MP0001881_abnormal_mammary_gland | 0.80839625 |
| 70 | MP0010094_abnormal_chromosome_stability | 0.78483990 |
| 71 | MP0005075_abnormal_melanosome_morpholog | 0.78107033 |
| 72 | MP0005197_abnormal_uvea_morphology | 0.76929690 |
| 73 | MP0003045_fibrosis | 0.75889651 |
| 74 | MP0004885_abnormal_endolymph | 0.75653651 |
| 75 | MP0000013_abnormal_adipose_tissue | 0.74499633 |
| 76 | MP0000367_abnormal_coat/_hair | 0.72151151 |
| 77 | MP0009931_abnormal_skin_appearance | 0.72021224 |
| 78 | MP0001835_abnormal_antigen_presentation | 0.68828444 |
| 79 | MP0001243_abnormal_dermal_layer | 0.66198392 |
| 80 | MP0002697_abnormal_eye_size | 0.65509308 |
| 81 | MP0002111_abnormal_tail_morphology | 0.62851533 |
| 82 | MP0008789_abnormal_olfactory_epithelium | 0.62595688 |
| 83 | MP0009785_altered_susceptibility_to | 0.61993092 |
| 84 | MP0001286_abnormal_eye_development | 0.61923257 |
| 85 | MP0006054_spinal_hemorrhage | 0.61449506 |
| 86 | MP0010386_abnormal_urinary_bladder | 0.61177803 |
| 87 | MP0001727_abnormal_embryo_implantation | 0.60794470 |
| 88 | MP0005671_abnormal_response_to | 0.58431749 |
| 89 | MP0006292_abnormal_olfactory_placode | 0.57467935 |
| 90 | MP0005084_abnormal_gallbladder_morpholo | 0.57206628 |
| 91 | MP0001340_abnormal_eyelid_morphology | 0.57168931 |
| 92 | MP0009765_abnormal_xenobiotic_induced | 0.57153500 |
| 93 | MP0002109_abnormal_limb_morphology | 0.55964907 |
| 94 | MP0000462_abnormal_digestive_system | 0.55927563 |
| 95 | MP0004264_abnormal_extraembryonic_tissu | 0.55839748 |
| 96 | MP0002006_tumorigenesis | 0.55619949 |
| 97 | MP0004142_abnormal_muscle_tone | 0.55457060 |
| 98 | MP0002736_abnormal_nociception_after | 0.54679028 |
| 99 | MP0002139_abnormal_hepatobiliary_system | 0.54412470 |
| 100 | MP0001853_heart_inflammation | 0.54385745 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Fragile nails (HP:0001808) | 8.20359630 |
| 2 | Onycholysis (HP:0001806) | 6.70594499 |
| 3 | Milia (HP:0001056) | 6.68045809 |
| 4 | Plantar hyperkeratosis (HP:0007556) | 6.12972689 |
| 5 | Palmoplantar hyperkeratosis (HP:0000972) | 4.88726993 |
| 6 | Palmar hyperkeratosis (HP:0010765) | 4.64260059 |
| 7 | Thick nail (HP:0001805) | 4.24020035 |
| 8 | Alopecia of scalp (HP:0002293) | 4.13867510 |
| 9 | Erythroderma (HP:0001019) | 4.12529275 |
| 10 | Nail dystrophy (HP:0008404) | 4.12077003 |
| 11 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 4.00937277 |
| 12 | Atrophic scars (HP:0001075) | 4.00791099 |
| 13 | Abnormality of nail color (HP:0100643) | 3.98937458 |
| 14 | Dry hair (HP:0011359) | 3.60361200 |
| 15 | Hypotrichosis (HP:0001006) | 3.56270685 |
| 16 | Congenital ichthyosiform erythroderma (HP:0007431) | 3.54725213 |
| 17 | Sparse eyelashes (HP:0000653) | 3.38013137 |
| 18 | Aplasia cutis congenita (HP:0001057) | 3.13970131 |
| 19 | Oral leukoplakia (HP:0002745) | 3.04991950 |
| 20 | Hypoplasia of dental enamel (HP:0006297) | 3.04661129 |
| 21 | Selective tooth agenesis (HP:0001592) | 2.96574026 |
| 22 | Abnormal blistering of the skin (HP:0008066) | 2.91605817 |
| 23 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 2.88798820 |
| 24 | Ridged nail (HP:0001807) | 2.72218741 |
| 25 | Parakeratosis (HP:0001036) | 2.68178674 |
| 26 | Brittle hair (HP:0002299) | 2.67491207 |
| 27 | Pili torti (HP:0003777) | 2.65672167 |
| 28 | Amniotic constriction ring (HP:0009775) | 2.65190336 |
| 29 | Abnormality of placental membranes (HP:0011409) | 2.65190336 |
| 30 | Right ventricular cardiomyopathy (HP:0011663) | 2.63598658 |
| 31 | Woolly hair (HP:0002224) | 2.61778771 |
| 32 | Congenital, generalized hypertrichosis (HP:0004540) | 2.58251903 |
| 33 | Abnormal hair laboratory examination (HP:0003328) | 2.53516351 |
| 34 | Abnormality of secondary sexual hair (HP:0009888) | 2.52256133 |
| 35 | Abnormality of the axillary hair (HP:0100134) | 2.52256133 |
| 36 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.51660327 |
| 37 | Abnormality of alanine metabolism (HP:0010916) | 2.51660327 |
| 38 | Hyperalaninemia (HP:0003348) | 2.51660327 |
| 39 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.50481450 |
| 40 | Aplasia of the phalanges of the hand (HP:0009802) | 2.50481450 |
| 41 | Aplasia involving bones of the extremities (HP:0009825) | 2.50481450 |
| 42 | Corneal erosion (HP:0200020) | 2.47935280 |
| 43 | Hypoplastic labia majora (HP:0000059) | 2.45069833 |
| 44 | Decreased subcutaneous fat (HP:0001002) | 2.42014980 |
| 45 | Conical tooth (HP:0000698) | 2.40862842 |
| 46 | Amelogenesis imperfecta (HP:0000705) | 2.40202533 |
| 47 | Xerostomia (HP:0000217) | 2.38900214 |
| 48 | Duplicated collecting system (HP:0000081) | 2.29553250 |
| 49 | Hypoplasia of the uterus (HP:0000013) | 2.29093120 |
| 50 | Fatigable weakness (HP:0003473) | 2.21560401 |
| 51 | Abnormality of the neuromuscular junction (HP:0003398) | 2.21560401 |
| 52 | Abnormality of the labia majora (HP:0012881) | 2.21306662 |
| 53 | Reduced antithrombin III activity (HP:0001976) | 2.19139494 |
| 54 | Split foot (HP:0001839) | 2.16451140 |
| 55 | Fragile skin (HP:0001030) | 2.14645961 |
| 56 | Abnormality of the renal collecting system (HP:0004742) | 2.12975528 |
| 57 | Abnormality of the distal phalanges of the toes (HP:0010182) | 2.10939528 |
| 58 | Nasolacrimal duct obstruction (HP:0000579) | 2.10079825 |
| 59 | Adrenal hypoplasia (HP:0000835) | 2.08084392 |
| 60 | Sparse scalp hair (HP:0002209) | 2.07035066 |
| 61 | Esophageal atresia (HP:0002032) | 2.03384474 |
| 62 | Palmoplantar keratoderma (HP:0000982) | 2.03352928 |
| 63 | Short middle phalanx of the 5th finger (HP:0004220) | 2.02885469 |
| 64 | Abnormality of the salivary glands (HP:0010286) | 2.02532345 |
| 65 | Popliteal pterygium (HP:0009756) | 2.02095922 |
| 66 | Aplastic anemia (HP:0001915) | 2.00473537 |
| 67 | Absent eyelashes (HP:0000561) | 1.99830294 |
| 68 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.99018890 |
| 69 | Anonychia (HP:0001798) | 1.98649743 |
| 70 | Lip pit (HP:0100267) | 1.97421999 |
| 71 | Poikiloderma (HP:0001029) | 1.94838950 |
| 72 | Squamous cell carcinoma (HP:0002860) | 1.94685712 |
| 73 | Pterygium (HP:0001059) | 1.93783787 |
| 74 | Methylmalonic acidemia (HP:0002912) | 1.92445501 |
| 75 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.92280790 |
| 76 | Abnormality of the dental root (HP:0006486) | 1.90648579 |
| 77 | Taurodontia (HP:0000679) | 1.90648579 |
| 78 | Abnormality of permanent molar morphology (HP:0011071) | 1.90648579 |
| 79 | Erythema (HP:0010783) | 1.90465617 |
| 80 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.89071128 |
| 81 | Recurrent corneal erosions (HP:0000495) | 1.87661771 |
| 82 | Bilateral sensorineural hearing impairment (HP:0008619) | 1.87231709 |
| 83 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 1.84068608 |
| 84 | Abnormality of the dental pulp (HP:0006479) | 1.82996681 |
| 85 | Abnormality of serum amino acid levels (HP:0003112) | 1.79288458 |
| 86 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.77564584 |
| 87 | Natal tooth (HP:0000695) | 1.75863257 |
| 88 | Abnormality of the alveolar ridges (HP:0006477) | 1.74712364 |
| 89 | Fibular aplasia (HP:0002990) | 1.71484691 |
| 90 | IgG deficiency (HP:0004315) | 1.71169584 |
| 91 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.69649148 |
| 92 | Abnormality of molar (HP:0011077) | 1.68291542 |
| 93 | Abnormality of molar morphology (HP:0011070) | 1.68291542 |
| 94 | Carious teeth (HP:0000670) | 1.67395334 |
| 95 | Cerebellar dysplasia (HP:0007033) | 1.66673110 |
| 96 | Abnormality of the lacrimal duct (HP:0011481) | 1.65915869 |
| 97 | Attenuation of retinal blood vessels (HP:0007843) | 1.65434264 |
| 98 | Congenital stationary night blindness (HP:0007642) | 1.65241818 |
| 99 | Abnormality of subcutaneous fat tissue (HP:0001001) | 1.63309670 |
| 100 | Sensory axonal neuropathy (HP:0003390) | 1.62140117 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MST1R | 4.06363157 |
| 2 | MAP4K2 | 3.51714162 |
| 3 | PBK | 3.01940886 |
| 4 | EPHA2 | 2.88765269 |
| 5 | EIF2AK3 | 2.79114369 |
| 6 | NEK1 | 2.64795776 |
| 7 | MST4 | 2.57017607 |
| 8 | TSSK6 | 2.53500756 |
| 9 | ZAK | 2.28320655 |
| 10 | BUB1 | 2.15878219 |
| 11 | BCKDK | 2.11437542 |
| 12 | TGFBR1 | 2.09504759 |
| 13 | MET | 1.99043238 |
| 14 | STK24 | 1.96269005 |
| 15 | MKNK1 | 1.84233583 |
| 16 | ADRBK2 | 1.76760329 |
| 17 | VRK2 | 1.71083947 |
| 18 | RPS6KA4 | 1.70771270 |
| 19 | TLK1 | 1.63069747 |
| 20 | EIF2AK1 | 1.60514642 |
| 21 | NUAK1 | 1.60158938 |
| 22 | PASK | 1.59611373 |
| 23 | MAP3K12 | 1.56291891 |
| 24 | ERBB3 | 1.49028946 |
| 25 | ARAF | 1.48589607 |
| 26 | STK38L | 1.46572015 |
| 27 | FLT3 | 1.41464892 |
| 28 | TXK | 1.32895041 |
| 29 | BRSK2 | 1.30834671 |
| 30 | MAPKAPK5 | 1.25337770 |
| 31 | RPS6KB2 | 1.22026492 |
| 32 | TRIM28 | 1.21557781 |
| 33 | PDK2 | 1.20825070 |
| 34 | ERBB4 | 1.19093601 |
| 35 | SRPK1 | 1.12827999 |
| 36 | MAP3K9 | 1.05980900 |
| 37 | ITK | 1.02792504 |
| 38 | NME2 | 0.96496983 |
| 39 | MAPKAPK3 | 0.95481423 |
| 40 | CDK19 | 0.93354411 |
| 41 | ADRBK1 | 0.92529264 |
| 42 | PLK3 | 0.91956832 |
| 43 | MAP3K2 | 0.91301916 |
| 44 | EPHB2 | 0.90816771 |
| 45 | AURKB | 0.90201069 |
| 46 | TRPM7 | 0.90107399 |
| 47 | GRK1 | 0.89344063 |
| 48 | LATS1 | 0.85677181 |
| 49 | LIMK1 | 0.82949423 |
| 50 | STK3 | 0.82421863 |
| 51 | PRKCE | 0.78173549 |
| 52 | KDR | 0.77741427 |
| 53 | TAF1 | 0.76758127 |
| 54 | OXSR1 | 0.76728765 |
| 55 | MAP3K6 | 0.76691441 |
| 56 | WEE1 | 0.75721922 |
| 57 | FER | 0.74708198 |
| 58 | PLK1 | 0.71991874 |
| 59 | GRK6 | 0.68010074 |
| 60 | PRKCI | 0.67837093 |
| 61 | EIF2AK2 | 0.66843370 |
| 62 | NME1 | 0.65869212 |
| 63 | FRK | 0.64815907 |
| 64 | PNCK | 0.64369496 |
| 65 | PINK1 | 0.61864433 |
| 66 | CSNK1G3 | 0.61451008 |
| 67 | TESK1 | 0.61414165 |
| 68 | IGF1R | 0.61378012 |
| 69 | PIK3CG | 0.60953211 |
| 70 | RPS6KA5 | 0.58691347 |
| 71 | WNK4 | 0.58542941 |
| 72 | PAK4 | 0.57643867 |
| 73 | VRK1 | 0.52317886 |
| 74 | MAP3K4 | 0.51533373 |
| 75 | BCR | 0.50659726 |
| 76 | CSNK1A1L | 0.49321984 |
| 77 | CSNK1G1 | 0.48239812 |
| 78 | BMPR1B | 0.47898011 |
| 79 | TESK2 | 0.47830421 |
| 80 | CSNK1G2 | 0.47087374 |
| 81 | CAMK2G | 0.46645148 |
| 82 | MYLK | 0.45770014 |
| 83 | STK10 | 0.45432893 |
| 84 | MAP2K7 | 0.44732031 |
| 85 | PIM2 | 0.44222770 |
| 86 | JAK3 | 0.43533803 |
| 87 | TTK | 0.41897542 |
| 88 | CDK7 | 0.41624303 |
| 89 | TEC | 0.41538726 |
| 90 | CDK8 | 0.38036371 |
| 91 | CAMKK2 | 0.37481785 |
| 92 | AURKA | 0.37193327 |
| 93 | CSNK2A1 | 0.36124173 |
| 94 | STK39 | 0.34684550 |
| 95 | IKBKB | 0.34319859 |
| 96 | CAMK2D | 0.33499143 |
| 97 | BRSK1 | 0.32886330 |
| 98 | DAPK1 | 0.32087043 |
| 99 | PLK4 | 0.31960194 |
| 100 | CSNK2A2 | 0.29667799 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.92291952 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 3.59493172 |
| 3 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.86897624 |
| 4 | Protein export_Homo sapiens_hsa03060 | 2.66491390 |
| 5 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.47102911 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.24850959 |
| 7 | Basal transcription factors_Homo sapiens_hsa03022 | 2.22673107 |
| 8 | Phototransduction_Homo sapiens_hsa04744 | 2.19993302 |
| 9 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.88704288 |
| 10 | Mismatch repair_Homo sapiens_hsa03430 | 1.69839792 |
| 11 | DNA replication_Homo sapiens_hsa03030 | 1.60679768 |
| 12 | RNA transport_Homo sapiens_hsa03013 | 1.56126150 |
| 13 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.53959175 |
| 14 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.47445217 |
| 15 | Asthma_Homo sapiens_hsa05310 | 1.47105306 |
| 16 | Spliceosome_Homo sapiens_hsa03040 | 1.44626445 |
| 17 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.44409341 |
| 18 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.42947395 |
| 19 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.39303802 |
| 20 | RNA degradation_Homo sapiens_hsa03018 | 1.39110894 |
| 21 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.38391674 |
| 22 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.37998208 |
| 23 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.36135063 |
| 24 | Allograft rejection_Homo sapiens_hsa05330 | 1.34895366 |
| 25 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.32785215 |
| 26 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.29275529 |
| 27 | Parkinsons disease_Homo sapiens_hsa05012 | 1.28715927 |
| 28 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.26149906 |
| 29 | Histidine metabolism_Homo sapiens_hsa00340 | 1.24936631 |
| 30 | Base excision repair_Homo sapiens_hsa03410 | 1.24228819 |
| 31 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.23351420 |
| 32 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.22566336 |
| 33 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.22522459 |
| 34 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.21660267 |
| 35 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.21057204 |
| 36 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.21011904 |
| 37 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.20664564 |
| 38 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.19104921 |
| 39 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.18179793 |
| 40 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.16720979 |
| 41 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.16038167 |
| 42 | Retinol metabolism_Homo sapiens_hsa00830 | 1.15049962 |
| 43 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.11691099 |
| 44 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.07333639 |
| 45 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.06807983 |
| 46 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.05926291 |
| 47 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.04789265 |
| 48 | Alzheimers disease_Homo sapiens_hsa05010 | 1.02966207 |
| 49 | Homologous recombination_Homo sapiens_hsa03440 | 1.01813058 |
| 50 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.00616832 |
| 51 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.99724379 |
| 52 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.98971847 |
| 53 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.94517768 |
| 54 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.93169269 |
| 55 | Purine metabolism_Homo sapiens_hsa00230 | 0.92624485 |
| 56 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.91750409 |
| 57 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.89894265 |
| 58 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.88078052 |
| 59 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.85743891 |
| 60 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.84657220 |
| 61 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.83836980 |
| 62 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.78616697 |
| 63 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.78043009 |
| 64 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.77395924 |
| 65 | Huntingtons disease_Homo sapiens_hsa05016 | 0.75967141 |
| 66 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.74915341 |
| 67 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.74605655 |
| 68 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.74592154 |
| 69 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.73583045 |
| 70 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.71377482 |
| 71 | Metabolic pathways_Homo sapiens_hsa01100 | 0.71209446 |
| 72 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.71100685 |
| 73 | Peroxisome_Homo sapiens_hsa04146 | 0.69996052 |
| 74 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.69865283 |
| 75 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.69271598 |
| 76 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.67220629 |
| 77 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.65999322 |
| 78 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.62060760 |
| 79 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.59645313 |
| 80 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.59494720 |
| 81 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.59067825 |
| 82 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.57986201 |
| 83 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.57393759 |
| 84 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.56811700 |
| 85 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.56667214 |
| 86 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.56551097 |
| 87 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.53992954 |
| 88 | ABC transporters_Homo sapiens_hsa02010 | 0.51773522 |
| 89 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.51621680 |
| 90 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.51541014 |
| 91 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.51383104 |
| 92 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.50801766 |
| 93 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.50354503 |
| 94 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.46351852 |
| 95 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.46174176 |
| 96 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.45517325 |
| 97 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.45287282 |
| 98 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.44111535 |
| 99 | Viral myocarditis_Homo sapiens_hsa05416 | 0.42033135 |
| 100 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.41730258 |

