

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 5.85791366 |
| 2 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.83986399 |
| 3 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.66338313 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 5.44984824 |
| 5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.44984824 |
| 6 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.45171867 |
| 7 | chaperone-mediated protein transport (GO:0072321) | 4.44477252 |
| 8 | ribosomal small subunit assembly (GO:0000028) | 4.44373324 |
| 9 | protein neddylation (GO:0045116) | 4.39335835 |
| 10 | respiratory electron transport chain (GO:0022904) | 4.15514318 |
| 11 | electron transport chain (GO:0022900) | 4.13179490 |
| 12 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.13051466 |
| 13 | proteasome assembly (GO:0043248) | 4.08389838 |
| 14 | protein complex biogenesis (GO:0070271) | 4.05540461 |
| 15 | cytidine deamination (GO:0009972) | 4.02310807 |
| 16 | cytidine metabolic process (GO:0046087) | 4.02310807 |
| 17 | cytidine catabolic process (GO:0006216) | 4.02310807 |
| 18 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.85913811 |
| 19 | NADH dehydrogenase complex assembly (GO:0010257) | 3.85913811 |
| 20 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.85913811 |
| 21 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.84761605 |
| 22 | sequestering of actin monomers (GO:0042989) | 3.77897351 |
| 23 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.73302861 |
| 24 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.72551277 |
| 25 | rRNA modification (GO:0000154) | 3.71043640 |
| 26 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.59369512 |
| 27 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.56868682 |
| 28 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.55997563 |
| 29 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.55997563 |
| 30 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.53746392 |
| 31 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.45659396 |
| 32 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.45659396 |
| 33 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.45659396 |
| 34 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.42794169 |
| 35 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.42794169 |
| 36 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.39535709 |
| 37 | translational termination (GO:0006415) | 3.38786923 |
| 38 | cotranslational protein targeting to membrane (GO:0006613) | 3.35538538 |
| 39 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.35081839 |
| 40 | viral transcription (GO:0019083) | 3.34971175 |
| 41 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.33977314 |
| 42 | protein targeting to ER (GO:0045047) | 3.32217858 |
| 43 | maturation of SSU-rRNA (GO:0030490) | 3.29459639 |
| 44 | platelet dense granule organization (GO:0060155) | 3.27877236 |
| 45 | mannosylation (GO:0097502) | 3.27125679 |
| 46 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.26343578 |
| 47 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.26343578 |
| 48 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.25252170 |
| 49 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.24361502 |
| 50 | negative regulation of ligase activity (GO:0051352) | 3.24361502 |
| 51 | rRNA methylation (GO:0031167) | 3.22332828 |
| 52 | intracellular protein transmembrane import (GO:0044743) | 3.19681997 |
| 53 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.18722853 |
| 54 | translational elongation (GO:0006414) | 3.16751701 |
| 55 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.15168609 |
| 56 | protein localization to endoplasmic reticulum (GO:0070972) | 3.13481797 |
| 57 | ribosomal large subunit biogenesis (GO:0042273) | 3.11551448 |
| 58 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.05548521 |
| 59 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.05254243 |
| 60 | termination of RNA polymerase III transcription (GO:0006386) | 3.05254243 |
| 61 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.03314161 |
| 62 | response to pheromone (GO:0019236) | 3.00689984 |
| 63 | translation (GO:0006412) | 2.97536617 |
| 64 | cytochrome complex assembly (GO:0017004) | 2.95662542 |
| 65 | ATP biosynthetic process (GO:0006754) | 2.94814855 |
| 66 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.93629789 |
| 67 | hydrogen ion transmembrane transport (GO:1902600) | 2.92998455 |
| 68 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.92409016 |
| 69 | base-excision repair, AP site formation (GO:0006285) | 2.91513055 |
| 70 | GPI anchor metabolic process (GO:0006505) | 2.91249073 |
| 71 | aldehyde catabolic process (GO:0046185) | 2.91143870 |
| 72 | respiratory chain complex IV assembly (GO:0008535) | 2.89203454 |
| 73 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.89196748 |
| 74 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.87498771 |
| 75 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.85862528 |
| 76 | GPI anchor biosynthetic process (GO:0006506) | 2.84802507 |
| 77 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.82973556 |
| 78 | oxidative phosphorylation (GO:0006119) | 2.82158059 |
| 79 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 2.81687071 |
| 80 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.80504680 |
| 81 | histone mRNA metabolic process (GO:0008334) | 2.80418783 |
| 82 | proton transport (GO:0015992) | 2.77081981 |
| 83 | translational initiation (GO:0006413) | 2.74376832 |
| 84 | L-fucose metabolic process (GO:0042354) | 2.74343683 |
| 85 | L-fucose catabolic process (GO:0042355) | 2.74343683 |
| 86 | fucose catabolic process (GO:0019317) | 2.74343683 |
| 87 | hydrogen transport (GO:0006818) | 2.71381172 |
| 88 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.70229741 |
| 89 | cellular protein complex disassembly (GO:0043624) | 2.69741086 |
| 90 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.69261588 |
| 91 | behavioral response to nicotine (GO:0035095) | 2.65495668 |
| 92 | neuron fate determination (GO:0048664) | 2.64508140 |
| 93 | positive regulation of ligase activity (GO:0051351) | 2.62674384 |
| 94 | negative regulation of mast cell activation (GO:0033004) | 2.59319826 |
| 95 | GTP biosynthetic process (GO:0006183) | 2.57513492 |
| 96 | actin nucleation (GO:0045010) | 2.57293719 |
| 97 | regulation of cellular amine metabolic process (GO:0033238) | 2.56162100 |
| 98 | cellular component biogenesis (GO:0044085) | 2.55286326 |
| 99 | positive regulation of cell cycle arrest (GO:0071158) | 2.54841277 |
| 100 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.54719496 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.34312019 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.06689815 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.58921632 |
| 4 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.53988519 |
| 5 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.39908750 |
| 6 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.04319769 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.95141144 |
| 8 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.62368730 |
| 9 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.60209488 |
| 10 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.52492046 |
| 11 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.45347793 |
| 12 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.45312179 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.40731686 |
| 14 | VDR_22108803_ChIP-Seq_LS180_Human | 2.37790473 |
| 15 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.24540565 |
| 16 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.23228927 |
| 17 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.20075785 |
| 18 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.19001468 |
| 19 | EWS_26573619_Chip-Seq_HEK293_Human | 2.15274826 |
| 20 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.15201812 |
| 21 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.06606803 |
| 22 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.05215356 |
| 23 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.00899551 |
| 24 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.86083533 |
| 25 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.83901081 |
| 26 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.81087665 |
| 27 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.79021944 |
| 28 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.74409134 |
| 29 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.73411667 |
| 30 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.71740388 |
| 31 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.69158400 |
| 32 | FUS_26573619_Chip-Seq_HEK293_Human | 1.64901867 |
| 33 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.55042256 |
| 34 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.52734917 |
| 35 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.50052621 |
| 36 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.48542927 |
| 37 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.46555744 |
| 38 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.46490259 |
| 39 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.44881930 |
| 40 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.43604810 |
| 41 | P300_19829295_ChIP-Seq_ESCs_Human | 1.43485409 |
| 42 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.38615721 |
| 43 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.38450733 |
| 44 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.37259849 |
| 45 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.36408975 |
| 46 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.35420935 |
| 47 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.33938828 |
| 48 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.29159659 |
| 49 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.28417354 |
| 50 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.27050602 |
| 51 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.26607078 |
| 52 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.26346031 |
| 53 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.24771014 |
| 54 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.24017503 |
| 55 | AR_20517297_ChIP-Seq_VCAP_Human | 1.23966034 |
| 56 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.23767536 |
| 57 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.21889987 |
| 58 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.21617945 |
| 59 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.21136151 |
| 60 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.19225388 |
| 61 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.19225388 |
| 62 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.18648268 |
| 63 | GATA3_26560356_Chip-Seq_TH2_Human | 1.18042437 |
| 64 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.17357752 |
| 65 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.15039833 |
| 66 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.15039833 |
| 67 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.14871126 |
| 68 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.14669315 |
| 69 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.13284471 |
| 70 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.12285145 |
| 71 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.08911504 |
| 72 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.07619729 |
| 73 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.07227901 |
| 74 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.05495341 |
| 75 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.04023902 |
| 76 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03570299 |
| 77 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.02940777 |
| 78 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.99432226 |
| 79 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.98345483 |
| 80 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.98345483 |
| 81 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.98213275 |
| 82 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.97946703 |
| 83 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.96620346 |
| 84 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.96361686 |
| 85 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.95377361 |
| 86 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.95263933 |
| 87 | MYB_26560356_Chip-Seq_TH2_Human | 0.94413018 |
| 88 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.94120226 |
| 89 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.94111236 |
| 90 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.91765203 |
| 91 | NCOR_22424771_ChIP-Seq_293T_Human | 0.91336178 |
| 92 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.91066256 |
| 93 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.91006907 |
| 94 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.90872277 |
| 95 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.89071465 |
| 96 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.88227565 |
| 97 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.87617094 |
| 98 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.87204064 |
| 99 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.86899953 |
| 100 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.86156873 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000569_abnormal_digit_pigmentation | 3.80312961 |
| 2 | MP0005671_abnormal_response_to | 3.78111330 |
| 3 | MP0002102_abnormal_ear_morphology | 3.23860502 |
| 4 | MP0006292_abnormal_olfactory_placode | 3.21932510 |
| 5 | MP0001986_abnormal_taste_sensitivity | 3.08752676 |
| 6 | MP0009379_abnormal_foot_pigmentation | 2.92082317 |
| 7 | MP0006072_abnormal_retinal_apoptosis | 2.87745055 |
| 8 | MP0001835_abnormal_antigen_presentation | 2.64877795 |
| 9 | MP0008877_abnormal_DNA_methylation | 2.16925614 |
| 10 | MP0003880_abnormal_central_pattern | 2.09979738 |
| 11 | MP0005075_abnormal_melanosome_morpholog | 2.06150286 |
| 12 | MP0004142_abnormal_muscle_tone | 1.95238377 |
| 13 | MP0003806_abnormal_nucleotide_metabolis | 1.90196176 |
| 14 | MP0005084_abnormal_gallbladder_morpholo | 1.89989255 |
| 15 | MP0008995_early_reproductive_senescence | 1.89776730 |
| 16 | MP0009785_altered_susceptibility_to | 1.85084320 |
| 17 | MP0002277_abnormal_respiratory_mucosa | 1.81488902 |
| 18 | MP0008872_abnormal_physiological_respon | 1.73827767 |
| 19 | MP0000372_irregular_coat_pigmentation | 1.70481573 |
| 20 | MP0004147_increased_porphyrin_level | 1.69272581 |
| 21 | MP0001905_abnormal_dopamine_level | 1.63247206 |
| 22 | MP0005253_abnormal_eye_physiology | 1.63206707 |
| 23 | MP0001873_stomach_inflammation | 1.62474307 |
| 24 | MP0003567_abnormal_fetal_cardiomyocyte | 1.60586039 |
| 25 | MP0008058_abnormal_DNA_repair | 1.57778679 |
| 26 | MP0004742_abnormal_vestibular_system | 1.54991753 |
| 27 | MP0003786_premature_aging | 1.52233013 |
| 28 | MP0005551_abnormal_eye_electrophysiolog | 1.51729528 |
| 29 | MP0003693_abnormal_embryo_hatching | 1.49620330 |
| 30 | MP0002736_abnormal_nociception_after | 1.48665896 |
| 31 | MP0003195_calcinosis | 1.48091640 |
| 32 | MP0006276_abnormal_autonomic_nervous | 1.47871027 |
| 33 | MP0001800_abnormal_humoral_immune | 1.44286305 |
| 34 | MP0008875_abnormal_xenobiotic_pharmacok | 1.42602099 |
| 35 | MP0002234_abnormal_pharynx_morphology | 1.42046894 |
| 36 | MP0002138_abnormal_hepatobiliary_system | 1.40463928 |
| 37 | MP0002938_white_spotting | 1.38289311 |
| 38 | MP0008961_abnormal_basal_metabolism | 1.37653438 |
| 39 | MP0001529_abnormal_vocalization | 1.32463913 |
| 40 | MP0002166_altered_tumor_susceptibility | 1.30358909 |
| 41 | MP0001968_abnormal_touch/_nociception | 1.27233027 |
| 42 | MP0002006_tumorigenesis | 1.26683598 |
| 43 | MP0003878_abnormal_ear_physiology | 1.26140675 |
| 44 | MP0005377_hearing/vestibular/ear_phenot | 1.26140675 |
| 45 | MP0006036_abnormal_mitochondrial_physio | 1.26074379 |
| 46 | MP0005645_abnormal_hypothalamus_physiol | 1.25131029 |
| 47 | MP0003011_delayed_dark_adaptation | 1.23361147 |
| 48 | MP0006035_abnormal_mitochondrial_morpho | 1.22927719 |
| 49 | MP0002095_abnormal_skin_pigmentation | 1.19451213 |
| 50 | MP0005000_abnormal_immune_tolerance | 1.15463600 |
| 51 | MP0000049_abnormal_middle_ear | 1.13746366 |
| 52 | MP0005423_abnormal_somatic_nervous | 1.12990498 |
| 53 | MP0009333_abnormal_splenocyte_physiolog | 1.08598897 |
| 54 | MP0003646_muscle_fatigue | 1.08370552 |
| 55 | MP0002723_abnormal_immune_serum | 1.08112088 |
| 56 | MP0001293_anophthalmia | 1.03146355 |
| 57 | MP0002148_abnormal_hypersensitivity_rea | 1.02936531 |
| 58 | MP0005646_abnormal_pituitary_gland | 0.99563018 |
| 59 | MP0010094_abnormal_chromosome_stability | 0.99185376 |
| 60 | MP0001819_abnormal_immune_cell | 0.97212110 |
| 61 | MP0005085_abnormal_gallbladder_physiolo | 0.96947744 |
| 62 | MP0002420_abnormal_adaptive_immunity | 0.96658434 |
| 63 | MP0001919_abnormal_reproductive_system | 0.94222285 |
| 64 | MP0004133_heterotaxia | 0.93197506 |
| 65 | MP0002452_abnormal_antigen_presenting | 0.92070308 |
| 66 | MP0005387_immune_system_phenotype | 0.90936897 |
| 67 | MP0001790_abnormal_immune_system | 0.90936897 |
| 68 | MP0003937_abnormal_limbs/digits/tail_de | 0.90645188 |
| 69 | MP0000566_synostosis | 0.89561641 |
| 70 | MP0002751_abnormal_autonomic_nervous | 0.87577213 |
| 71 | MP0004957_abnormal_blastocyst_morpholog | 0.87040661 |
| 72 | MP0000685_abnormal_immune_system | 0.86874141 |
| 73 | MP0009697_abnormal_copulation | 0.86154247 |
| 74 | MP0002876_abnormal_thyroid_physiology | 0.84956067 |
| 75 | MP0002398_abnormal_bone_marrow | 0.83197464 |
| 76 | MP0000631_abnormal_neuroendocrine_gland | 0.81186318 |
| 77 | MP0002405_respiratory_system_inflammati | 0.80192123 |
| 78 | MP0000716_abnormal_immune_system | 0.79883392 |
| 79 | MP0002272_abnormal_nervous_system | 0.79445625 |
| 80 | MP0001486_abnormal_startle_reflex | 0.79000661 |
| 81 | MP0002653_abnormal_ependyma_morphology | 0.78497297 |
| 82 | MP0000689_abnormal_spleen_morphology | 0.78187611 |
| 83 | MP0002837_dystrophic_cardiac_calcinosis | 0.77235293 |
| 84 | MP0003866_abnormal_defecation | 0.76915840 |
| 85 | MP0003186_abnormal_redox_activity | 0.76153567 |
| 86 | MP0000026_abnormal_inner_ear | 0.75516480 |
| 87 | MP0005389_reproductive_system_phenotype | 0.73403127 |
| 88 | MP0003718_maternal_effect | 0.72826268 |
| 89 | MP0005410_abnormal_fertilization | 0.72039489 |
| 90 | MP0004885_abnormal_endolymph | 0.71657118 |
| 91 | MP0001485_abnormal_pinna_reflex | 0.71328403 |
| 92 | MP0000703_abnormal_thymus_morphology | 0.70303904 |
| 93 | MP0003638_abnormal_response/metabolism_ | 0.68818451 |
| 94 | MP0003938_abnormal_ear_development | 0.68731928 |
| 95 | MP0002210_abnormal_sex_determination | 0.68532921 |
| 96 | MP0003137_abnormal_impulse_conducting | 0.67515450 |
| 97 | MP0005187_abnormal_penis_morphology | 0.67218566 |
| 98 | MP0004145_abnormal_muscle_electrophysio | 0.67008238 |
| 99 | MP0001119_abnormal_female_reproductive | 0.66554451 |
| 100 | MP0005025_abnormal_response_to | 0.66097811 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.19475672 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.13151911 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.81253941 |
| 4 | Aplastic anemia (HP:0001915) | 3.64438503 |
| 5 | Increased CSF lactate (HP:0002490) | 3.63860665 |
| 6 | Methylmalonic acidemia (HP:0002912) | 3.49432168 |
| 7 | Hepatocellular necrosis (HP:0001404) | 3.48376288 |
| 8 | Increased hepatocellular lipid droplets (HP:0006565) | 3.45210551 |
| 9 | Hypoproteinemia (HP:0003075) | 3.44006607 |
| 10 | Hypoplasia of the pons (HP:0012110) | 3.43310843 |
| 11 | Abnormality of the pons (HP:0007361) | 3.43141010 |
| 12 | Progressive macrocephaly (HP:0004481) | 3.41373085 |
| 13 | 3-Methylglutaconic aciduria (HP:0003535) | 3.41293888 |
| 14 | Acute encephalopathy (HP:0006846) | 3.34755779 |
| 15 | Lipid accumulation in hepatocytes (HP:0006561) | 3.28180522 |
| 16 | IgG deficiency (HP:0004315) | 3.22790567 |
| 17 | Hepatic necrosis (HP:0002605) | 3.19968732 |
| 18 | Abnormality of midbrain morphology (HP:0002418) | 2.98884759 |
| 19 | Molar tooth sign on MRI (HP:0002419) | 2.98884759 |
| 20 | Renal Fanconi syndrome (HP:0001994) | 2.98160388 |
| 21 | Methylmalonic aciduria (HP:0012120) | 2.89603890 |
| 22 | Cerebral edema (HP:0002181) | 2.88086714 |
| 23 | Congenital stationary night blindness (HP:0007642) | 2.79150269 |
| 24 | Pancreatic cysts (HP:0001737) | 2.78306809 |
| 25 | Abnormality of B cell number (HP:0010975) | 2.77803362 |
| 26 | True hermaphroditism (HP:0010459) | 2.62834197 |
| 27 | Congenital, generalized hypertrichosis (HP:0004540) | 2.59418734 |
| 28 | Type I transferrin isoform profile (HP:0003642) | 2.59175998 |
| 29 | Optic disc pallor (HP:0000543) | 2.58131674 |
| 30 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.56736829 |
| 31 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.56736829 |
| 32 | Increased intramyocellular lipid droplets (HP:0012240) | 2.55303764 |
| 33 | Pancreatic fibrosis (HP:0100732) | 2.55289263 |
| 34 | Severe combined immunodeficiency (HP:0004430) | 2.55228151 |
| 35 | Stomatitis (HP:0010280) | 2.52714985 |
| 36 | Nephronophthisis (HP:0000090) | 2.51905802 |
| 37 | Increased serum lactate (HP:0002151) | 2.51520147 |
| 38 | Abolished electroretinogram (ERG) (HP:0000550) | 2.49183870 |
| 39 | Exertional dyspnea (HP:0002875) | 2.44297472 |
| 40 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.39131413 |
| 41 | Abnormality of the prostate (HP:0008775) | 2.38749336 |
| 42 | Abnormal number of erythroid precursors (HP:0012131) | 2.36203075 |
| 43 | Abnormality of T cell number (HP:0011839) | 2.35946157 |
| 44 | T lymphocytopenia (HP:0005403) | 2.32713506 |
| 45 | Colon cancer (HP:0003003) | 2.32415563 |
| 46 | Reticulocytopenia (HP:0001896) | 2.30471888 |
| 47 | B lymphocytopenia (HP:0010976) | 2.29489458 |
| 48 | Increased IgM level (HP:0003496) | 2.26964835 |
| 49 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.26702340 |
| 50 | Lactic acidosis (HP:0003128) | 2.26354425 |
| 51 | Constricted visual fields (HP:0001133) | 2.25510775 |
| 52 | Macrocytic anemia (HP:0001972) | 2.21051950 |
| 53 | Renal cortical cysts (HP:0000803) | 2.19918528 |
| 54 | Thyroiditis (HP:0100646) | 2.18447900 |
| 55 | Increased muscle lipid content (HP:0009058) | 2.12156894 |
| 56 | Microvesicular hepatic steatosis (HP:0001414) | 2.11141360 |
| 57 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.07200724 |
| 58 | Abnormality of the renal medulla (HP:0100957) | 2.05675552 |
| 59 | Respiratory failure (HP:0002878) | 2.03914130 |
| 60 | Exercise intolerance (HP:0003546) | 2.03753556 |
| 61 | Pancytopenia (HP:0001876) | 2.02387162 |
| 62 | Type 2 muscle fiber atrophy (HP:0003554) | 2.01821779 |
| 63 | Generalized aminoaciduria (HP:0002909) | 2.01632075 |
| 64 | Attenuation of retinal blood vessels (HP:0007843) | 2.00716736 |
| 65 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.99613065 |
| 66 | IgM deficiency (HP:0002850) | 1.99425436 |
| 67 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.98800488 |
| 68 | Abnormality of the renal cortex (HP:0011035) | 1.97591805 |
| 69 | Testicular atrophy (HP:0000029) | 1.97188378 |
| 70 | Abnormality of T cells (HP:0002843) | 1.96845567 |
| 71 | Lethargy (HP:0001254) | 1.96018996 |
| 72 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.95865134 |
| 73 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.95865134 |
| 74 | Abnormal protein glycosylation (HP:0012346) | 1.95865134 |
| 75 | Abnormal glycosylation (HP:0012345) | 1.95865134 |
| 76 | Leukodystrophy (HP:0002415) | 1.93366372 |
| 77 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.91013609 |
| 78 | Dicarboxylic aciduria (HP:0003215) | 1.89343506 |
| 79 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.89343506 |
| 80 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.88031242 |
| 81 | Combined immunodeficiency (HP:0005387) | 1.87167085 |
| 82 | Abnormality of vitamin B metabolism (HP:0004340) | 1.86341851 |
| 83 | Panhypogammaglobulinemia (HP:0003139) | 1.83877375 |
| 84 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.79359690 |
| 85 | CNS demyelination (HP:0007305) | 1.78008278 |
| 86 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.76785061 |
| 87 | Bile duct proliferation (HP:0001408) | 1.76268213 |
| 88 | Abnormal biliary tract physiology (HP:0012439) | 1.76268213 |
| 89 | Abnormality of renal resorption (HP:0011038) | 1.75823251 |
| 90 | Supernumerary spleens (HP:0009799) | 1.75643850 |
| 91 | Abnormality of eosinophils (HP:0001879) | 1.75405791 |
| 92 | Pendular nystagmus (HP:0012043) | 1.73171332 |
| 93 | Reduced antithrombin III activity (HP:0001976) | 1.72203180 |
| 94 | Carpal bone hypoplasia (HP:0001498) | 1.72115719 |
| 95 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.71989926 |
| 96 | Oral leukoplakia (HP:0002745) | 1.71978896 |
| 97 | Hypothermia (HP:0002045) | 1.71776376 |
| 98 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.71756880 |
| 99 | Abnormality of alanine metabolism (HP:0010916) | 1.71756880 |
| 100 | Hyperalaninemia (HP:0003348) | 1.71756880 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 3.00878026 |
| 2 | MAP4K2 | 2.97685882 |
| 3 | VRK2 | 2.93880626 |
| 4 | TLK1 | 2.83463534 |
| 5 | GRK1 | 2.77200893 |
| 6 | TESK2 | 2.66147266 |
| 7 | ZAK | 2.64134445 |
| 8 | EIF2AK3 | 2.63047041 |
| 9 | BCKDK | 2.40751049 |
| 10 | TAOK3 | 2.35105537 |
| 11 | VRK1 | 2.33106399 |
| 12 | ADRBK2 | 2.28449524 |
| 13 | KDR | 2.27830471 |
| 14 | CDK19 | 2.16397711 |
| 15 | ERBB3 | 2.15917488 |
| 16 | TAF1 | 2.08859886 |
| 17 | BUB1 | 1.97184222 |
| 18 | PASK | 1.74053813 |
| 19 | MAP3K12 | 1.68281152 |
| 20 | KIT | 1.59662843 |
| 21 | NUAK1 | 1.58791895 |
| 22 | MKNK1 | 1.52045816 |
| 23 | BMPR1B | 1.50276317 |
| 24 | SCYL2 | 1.48058842 |
| 25 | TIE1 | 1.46312750 |
| 26 | MST4 | 1.44297125 |
| 27 | DYRK2 | 1.37590484 |
| 28 | WNK3 | 1.36219606 |
| 29 | SRPK1 | 1.35276856 |
| 30 | TEC | 1.34681195 |
| 31 | PLK3 | 1.32782632 |
| 32 | TSSK6 | 1.29312210 |
| 33 | TNIK | 1.21084776 |
| 34 | STK16 | 1.19992010 |
| 35 | NME1 | 1.19000004 |
| 36 | FRK | 1.17756065 |
| 37 | CDC7 | 1.16191846 |
| 38 | MAP4K1 | 1.13664115 |
| 39 | ITK | 1.08093926 |
| 40 | SYK | 0.99344928 |
| 41 | TRIM28 | 0.99170444 |
| 42 | PLK4 | 0.98010405 |
| 43 | OXSR1 | 0.94475609 |
| 44 | PBK | 0.91869633 |
| 45 | INSRR | 0.90252721 |
| 46 | PINK1 | 0.83159141 |
| 47 | MKNK2 | 0.77956434 |
| 48 | MAPK13 | 0.77231020 |
| 49 | RPS6KA4 | 0.72874553 |
| 50 | GRK6 | 0.71542967 |
| 51 | IKBKB | 0.71223575 |
| 52 | EIF2AK1 | 0.70090294 |
| 53 | WNK4 | 0.69783921 |
| 54 | TNK2 | 0.69137734 |
| 55 | PNCK | 0.67471451 |
| 56 | CSNK1G3 | 0.67463245 |
| 57 | WEE1 | 0.66448944 |
| 58 | PLK2 | 0.65486446 |
| 59 | TGFBR1 | 0.63604623 |
| 60 | CSNK1G1 | 0.60563593 |
| 61 | MAP3K4 | 0.60153014 |
| 62 | ATR | 0.58810508 |
| 63 | CDK8 | 0.58571025 |
| 64 | MAPKAPK3 | 0.54581466 |
| 65 | DYRK3 | 0.53247444 |
| 66 | DAPK1 | 0.52803507 |
| 67 | LIMK1 | 0.52728515 |
| 68 | MYLK | 0.52081447 |
| 69 | PRKCE | 0.50506410 |
| 70 | IKBKE | 0.49687211 |
| 71 | NEK1 | 0.49321591 |
| 72 | BTK | 0.48982347 |
| 73 | AURKB | 0.48454042 |
| 74 | RPS6KA5 | 0.48416188 |
| 75 | IGF1R | 0.46722203 |
| 76 | PIK3CG | 0.46451008 |
| 77 | FES | 0.46393142 |
| 78 | LCK | 0.46015861 |
| 79 | CSNK1G2 | 0.45889234 |
| 80 | LYN | 0.45629504 |
| 81 | FLT3 | 0.45575328 |
| 82 | OBSCN | 0.45320135 |
| 83 | ABL2 | 0.44921323 |
| 84 | BCR | 0.44667507 |
| 85 | NTRK3 | 0.44324072 |
| 86 | CSNK1A1L | 0.44303908 |
| 87 | CSNK2A1 | 0.44201447 |
| 88 | EIF2AK2 | 0.43679360 |
| 89 | CHEK2 | 0.41654056 |
| 90 | JAK3 | 0.39495223 |
| 91 | PRKCQ | 0.39089034 |
| 92 | CLK1 | 0.38955187 |
| 93 | CSNK2A2 | 0.38422341 |
| 94 | ERBB4 | 0.38320042 |
| 95 | PLK1 | 0.35362545 |
| 96 | PIM1 | 0.34093337 |
| 97 | CSF1R | 0.33382448 |
| 98 | GRK5 | 0.33044583 |
| 99 | CSNK1A1 | 0.32749643 |
| 100 | PRKACA | 0.32490041 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.36359558 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.75093471 |
| 3 | Ribosome_Homo sapiens_hsa03010 | 3.27638966 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.22757607 |
| 5 | Protein export_Homo sapiens_hsa03060 | 3.11790359 |
| 6 | Asthma_Homo sapiens_hsa05310 | 2.91270845 |
| 7 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.57484223 |
| 8 | Allograft rejection_Homo sapiens_hsa05330 | 2.50563914 |
| 9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.44687403 |
| 10 | RNA polymerase_Homo sapiens_hsa03020 | 2.35983069 |
| 11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.23823491 |
| 12 | Huntingtons disease_Homo sapiens_hsa05016 | 2.09835654 |
| 13 | Alzheimers disease_Homo sapiens_hsa05010 | 2.07884397 |
| 14 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.05480573 |
| 15 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.98283085 |
| 16 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.97041568 |
| 17 | Homologous recombination_Homo sapiens_hsa03440 | 1.91183541 |
| 18 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.88331038 |
| 19 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.71651879 |
| 20 | DNA replication_Homo sapiens_hsa03030 | 1.60826192 |
| 21 | Spliceosome_Homo sapiens_hsa03040 | 1.57877846 |
| 22 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.57562464 |
| 23 | RNA degradation_Homo sapiens_hsa03018 | 1.53030415 |
| 24 | Mismatch repair_Homo sapiens_hsa03430 | 1.52975858 |
| 25 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.48468890 |
| 26 | Base excision repair_Homo sapiens_hsa03410 | 1.43883733 |
| 27 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.41419932 |
| 28 | Basal transcription factors_Homo sapiens_hsa03022 | 1.41365807 |
| 29 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.39152508 |
| 30 | Phototransduction_Homo sapiens_hsa04744 | 1.38002747 |
| 31 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.29190401 |
| 32 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.23255960 |
| 33 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.23186566 |
| 34 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.18216347 |
| 35 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.07953006 |
| 36 | RNA transport_Homo sapiens_hsa03013 | 1.05718742 |
| 37 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.01920801 |
| 38 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.96704452 |
| 39 | Viral myocarditis_Homo sapiens_hsa05416 | 0.96280491 |
| 40 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.95417661 |
| 41 | Purine metabolism_Homo sapiens_hsa00230 | 0.95165932 |
| 42 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.92625372 |
| 43 | Peroxisome_Homo sapiens_hsa04146 | 0.86954876 |
| 44 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.86144011 |
| 45 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.84681496 |
| 46 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.84471517 |
| 47 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.84122992 |
| 48 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.82188644 |
| 49 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.80196765 |
| 50 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.79793514 |
| 51 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.77104530 |
| 52 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.73849904 |
| 53 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.72010320 |
| 54 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.68426218 |
| 55 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.68317231 |
| 56 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.65287724 |
| 57 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.65166381 |
| 58 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.64054182 |
| 59 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.59422146 |
| 60 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.58547301 |
| 61 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.57565297 |
| 62 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.57342974 |
| 63 | Olfactory transduction_Homo sapiens_hsa04740 | 0.56989292 |
| 64 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.56459483 |
| 65 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.56106112 |
| 66 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.52664072 |
| 67 | Metabolic pathways_Homo sapiens_hsa01100 | 0.52183138 |
| 68 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.50166143 |
| 69 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.49569902 |
| 70 | Retinol metabolism_Homo sapiens_hsa00830 | 0.49390962 |
| 71 | Leishmaniasis_Homo sapiens_hsa05140 | 0.48571724 |
| 72 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.46989688 |
| 73 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.46470587 |
| 74 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.46164901 |
| 75 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.44834008 |
| 76 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.44694173 |
| 77 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.44444017 |
| 78 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.44121246 |
| 79 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.44105672 |
| 80 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.43761655 |
| 81 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.43603077 |
| 82 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.43509434 |
| 83 | Taste transduction_Homo sapiens_hsa04742 | 0.41859312 |
| 84 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.40573400 |
| 85 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.40478533 |
| 86 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.39675814 |
| 87 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.38188966 |
| 88 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.36536096 |
| 89 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.36080464 |
| 90 | Nicotine addiction_Homo sapiens_hsa05033 | 0.35254994 |
| 91 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.33707981 |
| 92 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.33403216 |
| 93 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.32241165 |
| 94 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.31734245 |
| 95 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.29992120 |
| 96 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.29275201 |
| 97 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.27841593 |
| 98 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.25770753 |
| 99 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.24919983 |
| 100 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.23859373 |

