

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | protein neddylation (GO:0045116) | 4.99082685 |
| 2 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.90567024 |
| 3 | proteasome assembly (GO:0043248) | 4.82014279 |
| 4 | DNA deamination (GO:0045006) | 4.65360126 |
| 5 | cullin deneddylation (GO:0010388) | 4.05346000 |
| 6 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.02883289 |
| 7 | epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) | 3.96491975 |
| 8 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.91624529 |
| 9 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.82912086 |
| 10 | ATP synthesis coupled proton transport (GO:0015986) | 3.82912086 |
| 11 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.81829568 |
| 12 | positive regulation of amino acid transport (GO:0051957) | 3.79533846 |
| 13 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.73221373 |
| 14 | DNA replication checkpoint (GO:0000076) | 3.71536894 |
| 15 | protein deneddylation (GO:0000338) | 3.66509901 |
| 16 | ribosomal small subunit assembly (GO:0000028) | 3.61632760 |
| 17 | GPI anchor biosynthetic process (GO:0006506) | 3.55603822 |
| 18 | GPI anchor metabolic process (GO:0006505) | 3.53218420 |
| 19 | rRNA modification (GO:0000154) | 3.45958376 |
| 20 | L-methionine biosynthetic process (GO:0071265) | 3.45793753 |
| 21 | amino acid salvage (GO:0043102) | 3.45793753 |
| 22 | L-methionine salvage (GO:0071267) | 3.45793753 |
| 23 | base-excision repair, AP site formation (GO:0006285) | 3.45355803 |
| 24 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.44338018 |
| 25 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.44250482 |
| 26 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.44250482 |
| 27 | cellular ketone body metabolic process (GO:0046950) | 3.43913769 |
| 28 | protein complex biogenesis (GO:0070271) | 3.43183762 |
| 29 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.41332322 |
| 30 | NADH dehydrogenase complex assembly (GO:0010257) | 3.41332322 |
| 31 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.41332322 |
| 32 | termination of RNA polymerase III transcription (GO:0006386) | 3.39310493 |
| 33 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.39310493 |
| 34 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.35565779 |
| 35 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.35557011 |
| 36 | negative regulation of amino acid transport (GO:0051956) | 3.34717083 |
| 37 | positive regulation of prostaglandin secretion (GO:0032308) | 3.30581037 |
| 38 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.29029459 |
| 39 | DNA double-strand break processing (GO:0000729) | 3.22591429 |
| 40 | ribosome assembly (GO:0042255) | 3.19844249 |
| 41 | branched-chain amino acid catabolic process (GO:0009083) | 3.18669830 |
| 42 | serotonin receptor signaling pathway (GO:0007210) | 3.17635755 |
| 43 | rRNA methylation (GO:0031167) | 3.11184823 |
| 44 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.08266597 |
| 45 | cytidine deamination (GO:0009972) | 3.07779491 |
| 46 | cytidine metabolic process (GO:0046087) | 3.07779491 |
| 47 | cytidine catabolic process (GO:0006216) | 3.07779491 |
| 48 | ketone body metabolic process (GO:1902224) | 3.04772926 |
| 49 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 3.04653897 |
| 50 | positive regulation of catecholamine secretion (GO:0033605) | 3.00682451 |
| 51 | chromatin remodeling at centromere (GO:0031055) | 3.00380410 |
| 52 | positive regulation of organic acid transport (GO:0032892) | 2.92566294 |
| 53 | sequestering of actin monomers (GO:0042989) | 2.89496604 |
| 54 | regulation of glutamate secretion (GO:0014048) | 2.86947440 |
| 55 | response to pheromone (GO:0019236) | 2.86241366 |
| 56 | intracellular protein transmembrane import (GO:0044743) | 2.86002479 |
| 57 | kinetochore organization (GO:0051383) | 2.85946592 |
| 58 | aggressive behavior (GO:0002118) | 2.84089014 |
| 59 | kinetochore assembly (GO:0051382) | 2.83875094 |
| 60 | methionine biosynthetic process (GO:0009086) | 2.83675167 |
| 61 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.82671628 |
| 62 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.82083953 |
| 63 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.82056373 |
| 64 | kynurenine metabolic process (GO:0070189) | 2.79790826 |
| 65 | indolalkylamine metabolic process (GO:0006586) | 2.78729046 |
| 66 | chaperone-mediated protein transport (GO:0072321) | 2.78527878 |
| 67 | CENP-A containing nucleosome assembly (GO:0034080) | 2.76020818 |
| 68 | protein-cofactor linkage (GO:0018065) | 2.73076943 |
| 69 | respiratory chain complex IV assembly (GO:0008535) | 2.70993872 |
| 70 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.70194346 |
| 71 | iron-sulfur cluster assembly (GO:0016226) | 2.70030149 |
| 72 | metallo-sulfur cluster assembly (GO:0031163) | 2.70030149 |
| 73 | IMP biosynthetic process (GO:0006188) | 2.68478150 |
| 74 | electron transport chain (GO:0022900) | 2.68238688 |
| 75 | respiratory electron transport chain (GO:0022904) | 2.66460066 |
| 76 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.65891033 |
| 77 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.64029337 |
| 78 | regulation of chronic inflammatory response (GO:0002676) | 2.63849167 |
| 79 | tRNA processing (GO:0008033) | 2.63740342 |
| 80 | purine nucleobase biosynthetic process (GO:0009113) | 2.62787475 |
| 81 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.60722216 |
| 82 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.60722216 |
| 83 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.59921223 |
| 84 | resolution of meiotic recombination intermediates (GO:0000712) | 2.58967908 |
| 85 | regulation of prostaglandin secretion (GO:0032306) | 2.57770789 |
| 86 | synapsis (GO:0007129) | 2.57450398 |
| 87 | cellular response to nicotine (GO:0071316) | 2.56094486 |
| 88 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.54933919 |
| 89 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.54512701 |
| 90 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.54512701 |
| 91 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.54512701 |
| 92 | aspartate family amino acid biosynthetic process (GO:0009067) | 2.54354822 |
| 93 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.53402834 |
| 94 | nucleobase biosynthetic process (GO:0046112) | 2.53363569 |
| 95 | C-terminal protein lipidation (GO:0006501) | 2.52908065 |
| 96 | pharyngeal system development (GO:0060037) | 2.51003126 |
| 97 | platelet dense granule organization (GO:0060155) | 2.50966542 |
| 98 | piRNA metabolic process (GO:0034587) | 2.50885126 |
| 99 | male meiosis (GO:0007140) | 2.48626214 |
| 100 | ribosomal large subunit biogenesis (GO:0042273) | 2.48239622 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.28710503 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.81656394 |
| 3 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.44815753 |
| 4 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.36853595 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.24545088 |
| 6 | VDR_22108803_ChIP-Seq_LS180_Human | 3.01807950 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.88806501 |
| 8 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.72990986 |
| 9 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.70588419 |
| 10 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.64420525 |
| 11 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.58323563 |
| 12 | EWS_26573619_Chip-Seq_HEK293_Human | 2.50636462 |
| 13 | FUS_26573619_Chip-Seq_HEK293_Human | 2.36052849 |
| 14 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.33981584 |
| 15 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.26091177 |
| 16 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.16011170 |
| 17 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.15318883 |
| 18 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.11245121 |
| 19 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.09238424 |
| 20 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.03350565 |
| 21 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.01153419 |
| 22 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.98873062 |
| 23 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.98802247 |
| 24 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.97759802 |
| 25 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.97372184 |
| 26 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.91053479 |
| 27 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.89419495 |
| 28 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.84483902 |
| 29 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.68526064 |
| 30 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.62254265 |
| 31 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.60132195 |
| 32 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.58866713 |
| 33 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.56567205 |
| 34 | P300_19829295_ChIP-Seq_ESCs_Human | 1.56359105 |
| 35 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.54540519 |
| 36 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.53544714 |
| 37 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.52870407 |
| 38 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.50203285 |
| 39 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.50183885 |
| 40 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.47692669 |
| 41 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.45960281 |
| 42 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.45632931 |
| 43 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.44731321 |
| 44 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.43172136 |
| 45 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.40940151 |
| 46 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.40677839 |
| 47 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.38797935 |
| 48 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.37574274 |
| 49 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.36491800 |
| 50 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.36248047 |
| 51 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.28361159 |
| 52 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.25288952 |
| 53 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.23893470 |
| 54 | NCOR_22424771_ChIP-Seq_293T_Human | 1.20344080 |
| 55 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.19514367 |
| 56 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.19125395 |
| 57 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.19125395 |
| 58 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.18939252 |
| 59 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.17866832 |
| 60 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.17337604 |
| 61 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.15229120 |
| 62 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.15046723 |
| 63 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.15046723 |
| 64 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.14943574 |
| 65 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.13741643 |
| 66 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.11246230 |
| 67 | GATA3_26560356_Chip-Seq_TH2_Human | 1.10977913 |
| 68 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.07459820 |
| 69 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.03204879 |
| 70 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.02564580 |
| 71 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.02195542 |
| 72 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.01107503 |
| 73 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.00796852 |
| 74 | AR_20517297_ChIP-Seq_VCAP_Human | 1.00416797 |
| 75 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.99936823 |
| 76 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.99565338 |
| 77 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.99272569 |
| 78 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.99272569 |
| 79 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.97938883 |
| 80 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.97803892 |
| 81 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.97784408 |
| 82 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.97623327 |
| 83 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.97330662 |
| 84 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.97067036 |
| 85 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.96489272 |
| 86 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.95888889 |
| 87 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.94336324 |
| 88 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.93281301 |
| 89 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.93212463 |
| 90 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.92615473 |
| 91 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.91815279 |
| 92 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.91421732 |
| 93 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.91405461 |
| 94 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.91288075 |
| 95 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.90970859 |
| 96 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.90349998 |
| 97 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.89912541 |
| 98 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.89908618 |
| 99 | E2F7_22180533_ChIP-Seq_HELA_Human | 0.87512595 |
| 100 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.87164774 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006072_abnormal_retinal_apoptosis | 3.96572794 |
| 2 | MP0006292_abnormal_olfactory_placode | 3.23486892 |
| 3 | MP0002822_catalepsy | 3.09169332 |
| 4 | MP0005084_abnormal_gallbladder_morpholo | 2.94748440 |
| 5 | MP0002234_abnormal_pharynx_morphology | 2.89170914 |
| 6 | MP0003195_calcinosis | 2.76609681 |
| 7 | MP0002102_abnormal_ear_morphology | 2.65776110 |
| 8 | MP0002163_abnormal_gland_morphology | 2.53579947 |
| 9 | MP0008961_abnormal_basal_metabolism | 2.34900075 |
| 10 | MP0005671_abnormal_response_to | 2.29281007 |
| 11 | MP0000372_irregular_coat_pigmentation | 2.28548904 |
| 12 | MP0008058_abnormal_DNA_repair | 2.23428398 |
| 13 | MP0008877_abnormal_DNA_methylation | 2.12440246 |
| 14 | MP0005253_abnormal_eye_physiology | 2.01306369 |
| 15 | MP0010094_abnormal_chromosome_stability | 2.00398938 |
| 16 | MP0005646_abnormal_pituitary_gland | 1.84361213 |
| 17 | MP0005551_abnormal_eye_electrophysiolog | 1.83878752 |
| 18 | MP0003011_delayed_dark_adaptation | 1.78786826 |
| 19 | MP0004145_abnormal_muscle_electrophysio | 1.74681421 |
| 20 | MP0003806_abnormal_nucleotide_metabolis | 1.69938050 |
| 21 | MP0001293_anophthalmia | 1.66965056 |
| 22 | MP0008995_early_reproductive_senescence | 1.66402227 |
| 23 | MP0008872_abnormal_physiological_respon | 1.64414232 |
| 24 | MP0009379_abnormal_foot_pigmentation | 1.63903611 |
| 25 | MP0000049_abnormal_middle_ear | 1.56946281 |
| 26 | MP0003880_abnormal_central_pattern | 1.56828633 |
| 27 | MP0003786_premature_aging | 1.55076229 |
| 28 | MP0000631_abnormal_neuroendocrine_gland | 1.50805202 |
| 29 | MP0001764_abnormal_homeostasis | 1.43036075 |
| 30 | MP0004957_abnormal_blastocyst_morpholog | 1.42395034 |
| 31 | MP0008875_abnormal_xenobiotic_pharmacok | 1.40714821 |
| 32 | MP0002938_white_spotting | 1.39850987 |
| 33 | MP0005645_abnormal_hypothalamus_physiol | 1.39413160 |
| 34 | MP0005379_endocrine/exocrine_gland_phen | 1.39097123 |
| 35 | MP0003693_abnormal_embryo_hatching | 1.36891716 |
| 36 | MP0005075_abnormal_melanosome_morpholog | 1.36591532 |
| 37 | MP0004147_increased_porphyrin_level | 1.31798527 |
| 38 | MP0004142_abnormal_muscle_tone | 1.29713865 |
| 39 | MP0001919_abnormal_reproductive_system | 1.16862970 |
| 40 | MP0003252_abnormal_bile_duct | 1.15915008 |
| 41 | MP0003937_abnormal_limbs/digits/tail_de | 1.15839294 |
| 42 | MP0001879_abnormal_lymphatic_vessel | 1.14938615 |
| 43 | MP0000685_abnormal_immune_system | 1.14230410 |
| 44 | MP0008789_abnormal_olfactory_epithelium | 1.13634548 |
| 45 | MP0005085_abnormal_gallbladder_physiolo | 1.12815279 |
| 46 | MP0003283_abnormal_digestive_organ | 1.12242763 |
| 47 | MP0005389_reproductive_system_phenotype | 1.10663607 |
| 48 | MP0004215_abnormal_myocardial_fiber | 1.10210255 |
| 49 | MP0002009_preneoplasia | 1.09278276 |
| 50 | MP0000566_synostosis | 1.07024763 |
| 51 | MP0004043_abnormal_pH_regulation | 1.06925446 |
| 52 | MP0002736_abnormal_nociception_after | 1.06696293 |
| 53 | MP0001968_abnormal_touch/_nociception | 1.06523091 |
| 54 | MP0003718_maternal_effect | 1.03680975 |
| 55 | MP0005167_abnormal_blood-brain_barrier | 1.03244426 |
| 56 | MP0002928_abnormal_bile_duct | 1.01911696 |
| 57 | MP0006036_abnormal_mitochondrial_physio | 0.99813736 |
| 58 | MP0001986_abnormal_taste_sensitivity | 0.99723806 |
| 59 | MP0001984_abnormal_olfaction | 0.96840859 |
| 60 | MP0003787_abnormal_imprinting | 0.96433025 |
| 61 | MP0009745_abnormal_behavioral_response | 0.95950186 |
| 62 | MP0009250_abnormal_appendicular_skeleto | 0.95546731 |
| 63 | MP0002095_abnormal_skin_pigmentation | 0.95411003 |
| 64 | MP0008932_abnormal_embryonic_tissue | 0.95222440 |
| 65 | MP0009785_altered_susceptibility_to | 0.93310647 |
| 66 | MP0003119_abnormal_digestive_system | 0.93154813 |
| 67 | MP0005391_vision/eye_phenotype | 0.92411635 |
| 68 | MP0004782_abnormal_surfactant_physiolog | 0.91112568 |
| 69 | MP0010368_abnormal_lymphatic_system | 0.90726141 |
| 70 | MP0001188_hyperpigmentation | 0.89579318 |
| 71 | MP0002090_abnormal_vision | 0.89497381 |
| 72 | MP0002396_abnormal_hematopoietic_system | 0.88635365 |
| 73 | MP0003878_abnormal_ear_physiology | 0.88404965 |
| 74 | MP0005377_hearing/vestibular/ear_phenot | 0.88404965 |
| 75 | MP0002272_abnormal_nervous_system | 0.87128528 |
| 76 | MP0005410_abnormal_fertilization | 0.86805809 |
| 77 | MP0001800_abnormal_humoral_immune | 0.83009006 |
| 78 | MP0004885_abnormal_endolymph | 0.82767676 |
| 79 | MP0003567_abnormal_fetal_cardiomyocyte | 0.81323329 |
| 80 | MP0000383_abnormal_hair_follicle | 0.80867723 |
| 81 | MP0005195_abnormal_posterior_eye | 0.79643723 |
| 82 | MP0001529_abnormal_vocalization | 0.79510996 |
| 83 | MP0001929_abnormal_gametogenesis | 0.78106359 |
| 84 | MP0003122_maternal_imprinting | 0.77458795 |
| 85 | MP0002735_abnormal_chemical_nociception | 0.76035404 |
| 86 | MP0001963_abnormal_hearing_physiology | 0.75947047 |
| 87 | MP0000613_abnormal_salivary_gland | 0.73856466 |
| 88 | MP0001119_abnormal_female_reproductive | 0.73476495 |
| 89 | MP0000689_abnormal_spleen_morphology | 0.67903766 |
| 90 | MP0003646_muscle_fatigue | 0.67658555 |
| 91 | MP0003121_genomic_imprinting | 0.67306619 |
| 92 | MP0009697_abnormal_copulation | 0.67220270 |
| 93 | MP0002160_abnormal_reproductive_system | 0.67129946 |
| 94 | MP0002638_abnormal_pupillary_reflex | 0.65735618 |
| 95 | MP0002210_abnormal_sex_determination | 0.65699651 |
| 96 | MP0006276_abnormal_autonomic_nervous | 0.65421642 |
| 97 | MP0005310_abnormal_salivary_gland | 0.65252693 |
| 98 | MP0002405_respiratory_system_inflammati | 0.65117165 |
| 99 | MP0002233_abnormal_nose_morphology | 0.64974231 |
| 100 | MP0000427_abnormal_hair_cycle | 0.64605123 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Increased hepatocellular lipid droplets (HP:0006565) | 3.96065028 |
| 2 | Abnormality of the renal collecting system (HP:0004742) | 3.90300600 |
| 3 | Mitochondrial inheritance (HP:0001427) | 3.68341255 |
| 4 | Acute necrotizing encephalopathy (HP:0006965) | 3.53275907 |
| 5 | Lipid accumulation in hepatocytes (HP:0006561) | 3.48675998 |
| 6 | Increased CSF lactate (HP:0002490) | 3.33142204 |
| 7 | Methylmalonic acidemia (HP:0002912) | 3.28463039 |
| 8 | Cerebral edema (HP:0002181) | 3.20457520 |
| 9 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.14614180 |
| 10 | Hepatocellular necrosis (HP:0001404) | 3.11179410 |
| 11 | Congenital stationary night blindness (HP:0007642) | 3.10470498 |
| 12 | Duplicated collecting system (HP:0000081) | 3.04135540 |
| 13 | Acute encephalopathy (HP:0006846) | 2.97939244 |
| 14 | Hepatic necrosis (HP:0002605) | 2.95045458 |
| 15 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.91431188 |
| 16 | Concave nail (HP:0001598) | 2.90995925 |
| 17 | Progressive macrocephaly (HP:0004481) | 2.90675073 |
| 18 | 3-Methylglutaconic aciduria (HP:0003535) | 2.89535634 |
| 19 | Pancreatic cysts (HP:0001737) | 2.87197121 |
| 20 | Stenosis of the external auditory canal (HP:0000402) | 2.81800287 |
| 21 | True hermaphroditism (HP:0010459) | 2.78470812 |
| 22 | Hyperglycinemia (HP:0002154) | 2.77937754 |
| 23 | Abolished electroretinogram (ERG) (HP:0000550) | 2.77569307 |
| 24 | Abnormality of midbrain morphology (HP:0002418) | 2.71859181 |
| 25 | Molar tooth sign on MRI (HP:0002419) | 2.71859181 |
| 26 | Optic disc pallor (HP:0000543) | 2.67408271 |
| 27 | Pancreatic fibrosis (HP:0100732) | 2.66691613 |
| 28 | Nephronophthisis (HP:0000090) | 2.65388194 |
| 29 | Congenital, generalized hypertrichosis (HP:0004540) | 2.64130028 |
| 30 | Severe combined immunodeficiency (HP:0004430) | 2.60685821 |
| 31 | Short 1st metacarpal (HP:0010034) | 2.56890398 |
| 32 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 2.56890398 |
| 33 | Colon cancer (HP:0003003) | 2.50396641 |
| 34 | Exertional dyspnea (HP:0002875) | 2.48866948 |
| 35 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.47005893 |
| 36 | Methylmalonic aciduria (HP:0012120) | 2.45876804 |
| 37 | Renal Fanconi syndrome (HP:0001994) | 2.45618155 |
| 38 | Increased serum lactate (HP:0002151) | 2.41608961 |
| 39 | Type II lissencephaly (HP:0007260) | 2.34994347 |
| 40 | Medial flaring of the eyebrow (HP:0010747) | 2.34964382 |
| 41 | IgG deficiency (HP:0004315) | 2.32349984 |
| 42 | Lethargy (HP:0001254) | 2.30254898 |
| 43 | Abnormality of the 1st metacarpal (HP:0010009) | 2.29837381 |
| 44 | Abnormality of serum amino acid levels (HP:0003112) | 2.27437332 |
| 45 | Lactic acidosis (HP:0003128) | 2.27136964 |
| 46 | Increased intramyocellular lipid droplets (HP:0012240) | 2.23897238 |
| 47 | Ketosis (HP:0001946) | 2.23759588 |
| 48 | Abnormality of the labia minora (HP:0012880) | 2.19128880 |
| 49 | Attenuation of retinal blood vessels (HP:0007843) | 2.18227328 |
| 50 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.14652539 |
| 51 | Abnormality of the renal medulla (HP:0100957) | 2.05470664 |
| 52 | Aplastic anemia (HP:0001915) | 2.05255066 |
| 53 | Adactyly (HP:0009776) | 2.05230327 |
| 54 | Abnormality of vitamin B metabolism (HP:0004340) | 2.04880150 |
| 55 | Type I transferrin isoform profile (HP:0003642) | 2.04513534 |
| 56 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.04493506 |
| 57 | Abnormality of the renal cortex (HP:0011035) | 2.03599029 |
| 58 | Decreased central vision (HP:0007663) | 2.01818333 |
| 59 | Hypoproteinemia (HP:0003075) | 2.00882380 |
| 60 | Abnormal protein glycosylation (HP:0012346) | 2.00760581 |
| 61 | Abnormal glycosylation (HP:0012345) | 2.00760581 |
| 62 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.00760581 |
| 63 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.00760581 |
| 64 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.00164176 |
| 65 | Respiratory failure (HP:0002878) | 1.99608474 |
| 66 | Pendular nystagmus (HP:0012043) | 1.96497739 |
| 67 | Constricted visual fields (HP:0001133) | 1.96153335 |
| 68 | Abnormal drinking behavior (HP:0030082) | 1.91841211 |
| 69 | Polydipsia (HP:0001959) | 1.91841211 |
| 70 | Thyroiditis (HP:0100646) | 1.91616879 |
| 71 | Combined immunodeficiency (HP:0005387) | 1.91562472 |
| 72 | Type 2 muscle fiber atrophy (HP:0003554) | 1.91214174 |
| 73 | Renal cortical cysts (HP:0000803) | 1.90291956 |
| 74 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.88876593 |
| 75 | Abnormality of glycine metabolism (HP:0010895) | 1.87754202 |
| 76 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.87754202 |
| 77 | Parakeratosis (HP:0001036) | 1.86334586 |
| 78 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.84607131 |
| 79 | Sclerocornea (HP:0000647) | 1.83580387 |
| 80 | Abnormality of urine glucose concentration (HP:0011016) | 1.81569717 |
| 81 | Glycosuria (HP:0003076) | 1.81569717 |
| 82 | Pancytopenia (HP:0001876) | 1.80309983 |
| 83 | Hypomagnesemia (HP:0002917) | 1.79893884 |
| 84 | Cerebellar dysplasia (HP:0007033) | 1.79832492 |
| 85 | CNS demyelination (HP:0007305) | 1.77209831 |
| 86 | Reticulocytopenia (HP:0001896) | 1.76938042 |
| 87 | Degeneration of anterior horn cells (HP:0002398) | 1.76409326 |
| 88 | Abnormality of the anterior horn cell (HP:0006802) | 1.76409326 |
| 89 | Microvesicular hepatic steatosis (HP:0001414) | 1.75902415 |
| 90 | Meckel diverticulum (HP:0002245) | 1.75459315 |
| 91 | Large for gestational age (HP:0001520) | 1.75417458 |
| 92 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.74908357 |
| 93 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.74266725 |
| 94 | Dicarboxylic aciduria (HP:0003215) | 1.74266725 |
| 95 | Hyperglycinuria (HP:0003108) | 1.73875884 |
| 96 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.72048255 |
| 97 | Oligodactyly (hands) (HP:0001180) | 1.71028097 |
| 98 | Abnormality of the prostate (HP:0008775) | 1.70585733 |
| 99 | Hypoplasia of the uterus (HP:0000013) | 1.70326744 |
| 100 | Abnormality of methionine metabolism (HP:0010901) | 1.69881481 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BCKDK | 6.19096499 |
| 2 | EIF2AK3 | 3.94676922 |
| 3 | TESK2 | 3.50517296 |
| 4 | TXK | 2.82051152 |
| 5 | VRK2 | 2.73996858 |
| 6 | ZAK | 2.67390342 |
| 7 | TIE1 | 2.66426469 |
| 8 | BUB1 | 2.48197136 |
| 9 | NUAK1 | 2.47477303 |
| 10 | MST4 | 2.33827659 |
| 11 | GRK1 | 2.15144941 |
| 12 | ADRBK2 | 1.81609955 |
| 13 | MAP4K2 | 1.79481794 |
| 14 | PASK | 1.74442806 |
| 15 | VRK1 | 1.67856605 |
| 16 | EIF2AK2 | 1.60401552 |
| 17 | MUSK | 1.57328029 |
| 18 | EIF2AK1 | 1.53193175 |
| 19 | TLK1 | 1.53071620 |
| 20 | TEC | 1.48882679 |
| 21 | TRIM28 | 1.44458115 |
| 22 | PLK4 | 1.38216760 |
| 23 | PLK3 | 1.33223361 |
| 24 | NEK1 | 1.31198013 |
| 25 | MKNK1 | 1.29820013 |
| 26 | WNK3 | 1.28355957 |
| 27 | ERBB3 | 1.28171464 |
| 28 | MAP3K12 | 1.26417878 |
| 29 | TAOK3 | 1.21851369 |
| 30 | TSSK6 | 1.17740670 |
| 31 | STK39 | 1.13805706 |
| 32 | DYRK2 | 1.10539446 |
| 33 | FRK | 1.09924682 |
| 34 | BCR | 1.07629315 |
| 35 | TAF1 | 1.06512208 |
| 36 | WNK4 | 1.03588753 |
| 37 | BRSK2 | 0.97584825 |
| 38 | WEE1 | 0.97144346 |
| 39 | STK38L | 0.96064110 |
| 40 | CDC7 | 0.95966856 |
| 41 | PBK | 0.94267678 |
| 42 | MAP3K4 | 0.92326662 |
| 43 | MAPK13 | 0.90974953 |
| 44 | SRPK1 | 0.90460499 |
| 45 | BMPR1B | 0.90132413 |
| 46 | TNIK | 0.87284897 |
| 47 | OXSR1 | 0.84359923 |
| 48 | LIMK1 | 0.78939805 |
| 49 | ITK | 0.77395896 |
| 50 | KDR | 0.75516340 |
| 51 | RPS6KA4 | 0.74410329 |
| 52 | ATR | 0.73394791 |
| 53 | STK3 | 0.69004497 |
| 54 | MAP2K7 | 0.68495343 |
| 55 | MKNK2 | 0.65603463 |
| 56 | PLK1 | 0.64157536 |
| 57 | TGFBR1 | 0.62907650 |
| 58 | ACVR1B | 0.62538063 |
| 59 | CAMKK2 | 0.61691552 |
| 60 | KIT | 0.61526179 |
| 61 | INSRR | 0.59029341 |
| 62 | CSNK1G3 | 0.58876778 |
| 63 | EPHA4 | 0.57589443 |
| 64 | PRKCQ | 0.57557932 |
| 65 | STK24 | 0.57114132 |
| 66 | STK16 | 0.56688672 |
| 67 | PINK1 | 0.56512430 |
| 68 | CSNK1A1L | 0.55512370 |
| 69 | CSNK1G1 | 0.54339419 |
| 70 | NLK | 0.54242249 |
| 71 | GRK6 | 0.54191185 |
| 72 | NME1 | 0.54059962 |
| 73 | IKBKB | 0.52780886 |
| 74 | TTK | 0.50895930 |
| 75 | PLK2 | 0.46951962 |
| 76 | AURKB | 0.44782423 |
| 77 | PRKCE | 0.42175375 |
| 78 | PIM1 | 0.39948522 |
| 79 | MATK | 0.39281674 |
| 80 | DYRK3 | 0.38461999 |
| 81 | ADRBK1 | 0.37785587 |
| 82 | MAP2K2 | 0.37465710 |
| 83 | CSNK1G2 | 0.37445518 |
| 84 | DAPK1 | 0.37207046 |
| 85 | CSNK2A1 | 0.37190858 |
| 86 | CDK3 | 0.36529942 |
| 87 | PRKCG | 0.36371687 |
| 88 | FGFR1 | 0.36256089 |
| 89 | OBSCN | 0.32774227 |
| 90 | IGF1R | 0.32651997 |
| 91 | BRSK1 | 0.30858933 |
| 92 | MAPK15 | 0.30043502 |
| 93 | MAPKAPK3 | 0.29546505 |
| 94 | FLT3 | 0.28311777 |
| 95 | RPS6KA5 | 0.27794539 |
| 96 | CHEK2 | 0.26356102 |
| 97 | STK4 | 0.26288004 |
| 98 | LYN | 0.25477628 |
| 99 | LCK | 0.25145804 |
| 100 | CDK8 | 0.25108479 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.45884850 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.36619874 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.98383083 |
| 4 | Protein export_Homo sapiens_hsa03060 | 2.98341115 |
| 5 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.73808602 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.57356698 |
| 7 | Ribosome_Homo sapiens_hsa03010 | 2.52829775 |
| 8 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.51023984 |
| 9 | Parkinsons disease_Homo sapiens_hsa05012 | 2.37096621 |
| 10 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.25401894 |
| 11 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.97559349 |
| 12 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.91267852 |
| 13 | Phototransduction_Homo sapiens_hsa04744 | 1.84494142 |
| 14 | Mismatch repair_Homo sapiens_hsa03430 | 1.84083411 |
| 15 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.78949777 |
| 16 | Homologous recombination_Homo sapiens_hsa03440 | 1.70299943 |
| 17 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.68711843 |
| 18 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.68567012 |
| 19 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.66929284 |
| 20 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.66431505 |
| 21 | RNA degradation_Homo sapiens_hsa03018 | 1.66337307 |
| 22 | Basal transcription factors_Homo sapiens_hsa03022 | 1.59137107 |
| 23 | DNA replication_Homo sapiens_hsa03030 | 1.57826950 |
| 24 | Huntingtons disease_Homo sapiens_hsa05016 | 1.55997337 |
| 25 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.53623329 |
| 26 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.49367143 |
| 27 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.45744853 |
| 28 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.41426070 |
| 29 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.41239421 |
| 30 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.40856925 |
| 31 | Purine metabolism_Homo sapiens_hsa00230 | 1.40826109 |
| 32 | Alzheimers disease_Homo sapiens_hsa05010 | 1.37334238 |
| 33 | Spliceosome_Homo sapiens_hsa03040 | 1.34795899 |
| 34 | Sulfur relay system_Homo sapiens_hsa04122 | 1.34549195 |
| 35 | Base excision repair_Homo sapiens_hsa03410 | 1.27009485 |
| 36 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.22951424 |
| 37 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.22497320 |
| 38 | RNA transport_Homo sapiens_hsa03013 | 1.22039356 |
| 39 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.20046770 |
| 40 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.18173355 |
| 41 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.16397852 |
| 42 | Peroxisome_Homo sapiens_hsa04146 | 1.16381680 |
| 43 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.16200533 |
| 44 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.12843569 |
| 45 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.07612847 |
| 46 | Asthma_Homo sapiens_hsa05310 | 1.06729894 |
| 47 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.98142553 |
| 48 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.97574488 |
| 49 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.92607744 |
| 50 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.91798820 |
| 51 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.89582823 |
| 52 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.88265057 |
| 53 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.87894884 |
| 54 | Allograft rejection_Homo sapiens_hsa05330 | 0.81166107 |
| 55 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.77056506 |
| 56 | Metabolic pathways_Homo sapiens_hsa01100 | 0.75929362 |
| 57 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.75300402 |
| 58 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.75176429 |
| 59 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.74116937 |
| 60 | Retinol metabolism_Homo sapiens_hsa00830 | 0.72916827 |
| 61 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.65736718 |
| 62 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.65577537 |
| 63 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.64878164 |
| 64 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.64379230 |
| 65 | Olfactory transduction_Homo sapiens_hsa04740 | 0.63588944 |
| 66 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.63407600 |
| 67 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.62364672 |
| 68 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.61659100 |
| 69 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.61239535 |
| 70 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.57472364 |
| 71 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.57354682 |
| 72 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.52459793 |
| 73 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.50789231 |
| 74 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.47823428 |
| 75 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.47583792 |
| 76 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.47370761 |
| 77 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.46408305 |
| 78 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.45612370 |
| 79 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.44453811 |
| 80 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.42830167 |
| 81 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.42821759 |
| 82 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.41630673 |
| 83 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.40761990 |
| 84 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.40496860 |
| 85 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.39742295 |
| 86 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.39146721 |
| 87 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.38228274 |
| 88 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.38163535 |
| 89 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.37656130 |
| 90 | Cell cycle_Homo sapiens_hsa04110 | 0.37126436 |
| 91 | Carbon metabolism_Homo sapiens_hsa01200 | 0.36912892 |
| 92 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.36601999 |
| 93 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.36237128 |
| 94 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.36047035 |
| 95 | Salivary secretion_Homo sapiens_hsa04970 | 0.35503722 |
| 96 | ABC transporters_Homo sapiens_hsa02010 | 0.35503366 |
| 97 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.33912949 |
| 98 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.32489316 |
| 99 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.31309993 |
| 100 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.27823823 |

