HNRNPA1P43

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.98603929
2ATP synthesis coupled proton transport (GO:0015986)5.91109567
3energy coupled proton transport, down electrochemical gradient (GO:0015985)5.91109567
4establishment of protein localization to mitochondrial membrane (GO:0090151)4.53255516
5ribosomal small subunit assembly (GO:0000028)4.40575075
6viral transcription (GO:0019083)4.29761549
7exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 4.28594822
8nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)4.18526236
9DNA deamination (GO:0045006)4.11400546
10translational termination (GO:0006415)4.11189858
11mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.08831221
12mitochondrial respiratory chain complex I assembly (GO:0032981)4.08831221
13NADH dehydrogenase complex assembly (GO:0010257)4.08831221
14maturation of SSU-rRNA (GO:0030490)4.04561313
15ribosomal large subunit biogenesis (GO:0042273)3.97111715
16inner mitochondrial membrane organization (GO:0007007)3.79914213
17translational elongation (GO:0006414)3.77157391
18DNA damage response, detection of DNA damage (GO:0042769)3.76837004
19SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.76429788
20cotranslational protein targeting to membrane (GO:0006613)3.72047322
21mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.70610382
22protein complex biogenesis (GO:0070271)3.67745993
23protein polyglutamylation (GO:0018095)3.67669282
24protein targeting to ER (GO:0045047)3.66304338
25establishment of protein localization to endoplasmic reticulum (GO:0072599)3.47691226
26protein localization to endoplasmic reticulum (GO:0070972)3.47644884
27retinal cone cell development (GO:0046549)3.46444789
28ATP biosynthetic process (GO:0006754)3.44948360
29IMP biosynthetic process (GO:0006188)3.42045120
30mitochondrial respiratory chain complex assembly (GO:0033108)3.40408845
31GMP metabolic process (GO:0046037)3.40010719
32RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.35417467
33electron transport chain (GO:0022900)3.31965715
34respiratory electron transport chain (GO:0022904)3.30215930
35protein neddylation (GO:0045116)3.26882645
36purine-containing compound salvage (GO:0043101)3.23905712
37translational initiation (GO:0006413)3.19958378
38somatic hypermutation of immunoglobulin genes (GO:0016446)3.19883454
39somatic diversification of immune receptors via somatic mutation (GO:0002566)3.19883454
40RNA destabilization (GO:0050779)3.18781654
41rRNA modification (GO:0000154)3.15525001
42chaperone-mediated protein transport (GO:0072321)3.15072600
43purine nucleoside triphosphate biosynthetic process (GO:0009145)3.14965906
44proteasome assembly (GO:0043248)3.14540268
45mismatch repair (GO:0006298)3.10932763
46translation (GO:0006412)3.10365314
47nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.09680818
48purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.08614575
49nucleotide-excision repair, DNA damage removal (GO:0000718)3.08145715
50DNA excision (GO:0044349)3.08145715
51viral life cycle (GO:0019058)3.06881862
52L-fucose catabolic process (GO:0042355)3.05517045
53fucose catabolic process (GO:0019317)3.05517045
54L-fucose metabolic process (GO:0042354)3.05517045
55behavioral response to nicotine (GO:0035095)3.04343181
56RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.01002544
57tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.01002544
58urate metabolic process (GO:0046415)3.00995212
59cellular protein complex disassembly (GO:0043624)2.98121718
60sulfation (GO:0051923)2.96930683
61water-soluble vitamin biosynthetic process (GO:0042364)2.95012618
62organelle disassembly (GO:1903008)2.93349931
63regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.91075948
64piRNA metabolic process (GO:0034587)2.86843667
65purine ribonucleoside monophosphate biosynthetic process (GO:0009168)2.83425646
66purine nucleoside monophosphate biosynthetic process (GO:0009127)2.83425646
67termination of RNA polymerase I transcription (GO:0006363)2.82448270
68transcription elongation from RNA polymerase I promoter (GO:0006362)2.75314107
69S-adenosylmethionine metabolic process (GO:0046500)2.73261448
70cell fate commitment involved in formation of primary germ layer (GO:0060795)2.70492604
71regulation of DNA endoreduplication (GO:0032875)2.70447356
72nuclear-transcribed mRNA catabolic process (GO:0000956)2.70400925
73purine nucleobase biosynthetic process (GO:0009113)2.67883516
74CENP-A containing nucleosome assembly (GO:0034080)2.67731882
75replication fork processing (GO:0031297)2.66722482
76regulation of nuclear cell cycle DNA replication (GO:0033262)2.66655600
77spliceosomal snRNP assembly (GO:0000387)2.66297154
78chromatin remodeling at centromere (GO:0031055)2.66172093
79pseudouridine synthesis (GO:0001522)2.65545242
80activated T cell proliferation (GO:0050798)2.65228578
81regulation of chronic inflammatory response (GO:0002676)2.64516299
82IMP metabolic process (GO:0046040)2.64278852
83rRNA processing (GO:0006364)2.64173977
84seminiferous tubule development (GO:0072520)2.61947926
85ribonucleoside triphosphate biosynthetic process (GO:0009201)2.61176231
86somite development (GO:0061053)2.60907333
87rRNA metabolic process (GO:0016072)2.60043635
88recombinational repair (GO:0000725)2.59861058
89mRNA catabolic process (GO:0006402)2.59273295
90double-strand break repair via homologous recombination (GO:0000724)2.58968825
91rRNA methylation (GO:0031167)2.58798484
92histone exchange (GO:0043486)2.58429985
93negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class 2.58334169
94negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.57773573
95purine nucleotide salvage (GO:0032261)2.57725951
96cullin deneddylation (GO:0010388)2.55507635
97negative regulation of DNA-dependent DNA replication (GO:2000104)2.54029299
98detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.53785125
99response to interferon-beta (GO:0035456)2.52765343
100preassembly of GPI anchor in ER membrane (GO:0016254)2.52238627

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.03288509
2GABP_17652178_ChIP-ChIP_JURKAT_Human4.01248621
3EST1_17652178_ChIP-ChIP_JURKAT_Human3.62110036
4HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.53813103
5ELF1_17652178_ChIP-ChIP_JURKAT_Human3.46157556
6SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.24844730
7HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.17967994
8VDR_22108803_ChIP-Seq_LS180_Human2.93897848
9ZNF274_21170338_ChIP-Seq_K562_Hela2.65046902
10MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.60174921
11VDR_23849224_ChIP-Seq_CD4+_Human2.58124167
12E2F4_17652178_ChIP-ChIP_JURKAT_Human2.53774283
13CREB1_15753290_ChIP-ChIP_HEK293T_Human2.50619708
14EWS_26573619_Chip-Seq_HEK293_Human2.46049657
15ELK1_19687146_ChIP-ChIP_HELA_Human2.43900433
16CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.31437594
17JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.27142571
18ETS1_20019798_ChIP-Seq_JURKAT_Human2.27008614
19E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.18434110
20TAF15_26573619_Chip-Seq_HEK293_Human2.07754734
21MYC_18940864_ChIP-ChIP_HL60_Human2.05228585
22EZH2_22144423_ChIP-Seq_EOC_Human2.04746999
23MYC_18555785_ChIP-Seq_MESCs_Mouse2.03802076
24FLI1_27457419_Chip-Seq_LIVER_Mouse2.01796132
25FOXP3_21729870_ChIP-Seq_TREG_Human1.98901048
26FUS_26573619_Chip-Seq_HEK293_Human1.97464450
27RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.87259300
28IRF1_19129219_ChIP-ChIP_H3396_Human1.83244798
29ZFP57_27257070_Chip-Seq_ESCs_Mouse1.69804578
30GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.68698891
31POU3F2_20337985_ChIP-ChIP_501MEL_Human1.65509734
32NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.62557746
33IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.62284981
34ER_23166858_ChIP-Seq_MCF-7_Human1.60547884
35SRF_21415370_ChIP-Seq_HL-1_Mouse1.55265115
36PCGF2_27294783_Chip-Seq_ESCs_Mouse1.55078252
37PADI4_21655091_ChIP-ChIP_MCF-7_Human1.53430617
38PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.52316339
39CTBP1_25329375_ChIP-Seq_LNCAP_Human1.50421972
40P300_19829295_ChIP-Seq_ESCs_Human1.46540320
41HOXB4_20404135_ChIP-ChIP_EML_Mouse1.45412009
42GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.45031603
43TTF2_22483619_ChIP-Seq_HELA_Human1.44085093
44EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.42489926
45IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.41334911
46CBP_20019798_ChIP-Seq_JUKART_Human1.41334911
47TP53_22573176_ChIP-Seq_HFKS_Human1.40667967
48POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.39775596
49EGR1_23403033_ChIP-Seq_LIVER_Mouse1.35342617
50GBX2_23144817_ChIP-Seq_PC3_Human1.30881564
51PCGF2_27294783_Chip-Seq_NPCs_Mouse1.29572566
52MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.29359109
53CTBP2_25329375_ChIP-Seq_LNCAP_Human1.28854309
54PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.28675005
55CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.27819525
56TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.27071419
57RBPJ_22232070_ChIP-Seq_NCS_Mouse1.24082179
58NOTCH1_21737748_ChIP-Seq_TLL_Human1.24072322
59MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.22340330
60POU5F1_16153702_ChIP-ChIP_HESCs_Human1.20289537
61MYC_19030024_ChIP-ChIP_MESCs_Mouse1.18165467
62RNF2_27304074_Chip-Seq_NSC_Mouse1.16043393
63FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.15059996
64MYC_18358816_ChIP-ChIP_MESCs_Mouse1.14045297
65AR_20517297_ChIP-Seq_VCAP_Human1.11694373
66BMI1_23680149_ChIP-Seq_NPCS_Mouse1.11301129
67XRN2_22483619_ChIP-Seq_HELA_Human1.11170110
68CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.11086247
69DCP1A_22483619_ChIP-Seq_HELA_Human1.10464761
70FOXA1_27270436_Chip-Seq_PROSTATE_Human1.10447194
71FOXA1_25329375_ChIP-Seq_VCAP_Human1.10447194
72IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.07859354
73TP63_19390658_ChIP-ChIP_HaCaT_Human1.05678927
74YY1_21170310_ChIP-Seq_MESCs_Mouse1.03901239
75FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.03257181
76AUTS2_25519132_ChIP-Seq_293T-REX_Human1.01412972
77ELK1_22589737_ChIP-Seq_MCF10A_Human1.00091080
78SUZ12_27294783_Chip-Seq_NPCs_Mouse0.99975464
79NFE2_27457419_Chip-Seq_LIVER_Mouse0.99676438
80PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.98766050
81IGF1R_20145208_ChIP-Seq_DFB_Human0.97892616
82TCF4_22108803_ChIP-Seq_LS180_Human0.97519930
83PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.96129468
84NCOR_22424771_ChIP-Seq_293T_Human0.96122412
85CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.95580748
86SOX2_19829295_ChIP-Seq_ESCs_Human0.95198340
87NANOG_19829295_ChIP-Seq_ESCs_Human0.95198340
88EZH2_27294783_Chip-Seq_NPCs_Mouse0.94679590
89CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.94529980
90BCAT_22108803_ChIP-Seq_LS180_Human0.93950052
91MYC_19079543_ChIP-ChIP_MESCs_Mouse0.91612821
92CBX2_27304074_Chip-Seq_ESCs_Mouse0.90489777
93KLF5_20875108_ChIP-Seq_MESCs_Mouse0.90478174
94TDRD3_21172665_ChIP-Seq_MCF-7_Human0.90223726
95YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.89004705
96SOX2_16153702_ChIP-ChIP_HESCs_Human0.88967029
97GABP_19822575_ChIP-Seq_HepG2_Human0.88680262
98GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.88622847
99UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.88517546
100FOXA1_21572438_ChIP-Seq_LNCaP_Human0.88443929

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008877_abnormal_DNA_methylation3.85771088
2MP0006072_abnormal_retinal_apoptosis2.51944359
3MP0005671_abnormal_response_to2.40571021
4MP0005646_abnormal_pituitary_gland2.38860307
5MP0009379_abnormal_foot_pigmentation2.38106559
6MP0006292_abnormal_olfactory_placode2.36517654
7MP0008058_abnormal_DNA_repair2.19873529
8MP0009697_abnormal_copulation2.02251162
9MP0005551_abnormal_eye_electrophysiolog2.02208643
10MP0000372_irregular_coat_pigmentation2.01900800
11MP0002090_abnormal_vision2.01164474
12MP0002938_white_spotting2.00005210
13MP0003880_abnormal_central_pattern1.92923903
14MP0002876_abnormal_thyroid_physiology1.89694668
15MP0005253_abnormal_eye_physiology1.87117183
16MP0002102_abnormal_ear_morphology1.86700157
17MP0004147_increased_porphyrin_level1.85630182
18MP0002138_abnormal_hepatobiliary_system1.82651455
19MP0002736_abnormal_nociception_after1.78283475
20MP0008995_early_reproductive_senescence1.77536272
21MP0010094_abnormal_chromosome_stability1.76328145
22MP0001835_abnormal_antigen_presentation1.72674378
23MP0001968_abnormal_touch/_nociception1.72095090
24MP0003724_increased_susceptibility_to1.65141464
25MP0001529_abnormal_vocalization1.62702069
26MP0003878_abnormal_ear_physiology1.61718905
27MP0005377_hearing/vestibular/ear_phenot1.61718905
28MP0003195_calcinosis1.59170752
29MP0003787_abnormal_imprinting1.57096712
30MP0000569_abnormal_digit_pigmentation1.55116987
31MP0000049_abnormal_middle_ear1.52980024
32MP0001293_anophthalmia1.47786079
33MP0001348_abnormal_lacrimal_gland1.46667454
34MP0005084_abnormal_gallbladder_morpholo1.45760084
35MP0001986_abnormal_taste_sensitivity1.43357926
36MP0003718_maternal_effect1.42862487
37MP0004215_abnormal_myocardial_fiber1.41254222
38MP0008872_abnormal_physiological_respon1.41253612
39MP0005075_abnormal_melanosome_morpholog1.41129317
40MP0000613_abnormal_salivary_gland1.40879196
41MP0002277_abnormal_respiratory_mucosa1.39709554
42MP0005167_abnormal_blood-brain_barrier1.34036800
43MP0003806_abnormal_nucleotide_metabolis1.31284015
44MP0002254_reproductive_system_inflammat1.28904913
45MP0003567_abnormal_fetal_cardiomyocyte1.26728472
46MP0002837_dystrophic_cardiac_calcinosis1.26686397
47MP0003693_abnormal_embryo_hatching1.26457921
48MP0003786_premature_aging1.22891176
49MP0005645_abnormal_hypothalamus_physiol1.22437616
50MP0002210_abnormal_sex_determination1.20081329
51MP0004133_heterotaxia1.18364832
52MP0002272_abnormal_nervous_system1.18339108
53MP0000631_abnormal_neuroendocrine_gland1.18263919
54MP0003136_yellow_coat_color1.18255776
55MP0002160_abnormal_reproductive_system1.17178296
56MP0001486_abnormal_startle_reflex1.16471666
57MP0004142_abnormal_muscle_tone1.15333490
58MP0003011_delayed_dark_adaptation1.14203343
59MP0000653_abnormal_sex_gland1.12887366
60MP0004885_abnormal_endolymph1.10239235
61MP0001929_abnormal_gametogenesis1.10192888
62MP0001145_abnormal_male_reproductive1.10030028
63MP0001485_abnormal_pinna_reflex1.08673854
64MP0005647_abnormal_sex_gland1.08320205
65MP0008057_abnormal_DNA_replication1.05057044
66MP0005595_abnormal_vascular_smooth1.04565286
67MP0005389_reproductive_system_phenotype1.01828313
68MP0003119_abnormal_digestive_system0.97918840
69MP0009780_abnormal_chondrocyte_physiolo0.95728148
70MP0005195_abnormal_posterior_eye0.95314357
71MP0002751_abnormal_autonomic_nervous0.94304072
72MP0008789_abnormal_olfactory_epithelium0.94170448
73MP0002095_abnormal_skin_pigmentation0.93460909
74MP0001919_abnormal_reproductive_system0.92405912
75MP0003937_abnormal_limbs/digits/tail_de0.91345072
76MP0005391_vision/eye_phenotype0.91013357
77MP0004957_abnormal_blastocyst_morpholog0.90934154
78MP0006035_abnormal_mitochondrial_morpho0.90850613
79MP0003111_abnormal_nucleus_morphology0.89745852
80MP0002638_abnormal_pupillary_reflex0.88847436
81MP0000566_synostosis0.87272216
82MP0001346_abnormal_lacrimal_gland0.84645298
83MP0005379_endocrine/exocrine_gland_phen0.83925654
84MP0003698_abnormal_male_reproductive0.82769749
85MP0008875_abnormal_xenobiotic_pharmacok0.82552657
86MP0002928_abnormal_bile_duct0.80695416
87MP0009046_muscle_twitch0.79260434
88MP0006036_abnormal_mitochondrial_physio0.79005294
89MP0002752_abnormal_somatic_nervous0.78417298
90MP0003121_genomic_imprinting0.78116141
91MP0005174_abnormal_tail_pigmentation0.77716303
92MP0003950_abnormal_plasma_membrane0.77291250
93MP0002006_tumorigenesis0.75077471
94MP0009745_abnormal_behavioral_response0.72506912
95MP0002282_abnormal_trachea_morphology0.72228390
96MP0003077_abnormal_cell_cycle0.71659424
97MP0002234_abnormal_pharynx_morphology0.69648444
98MP0001119_abnormal_female_reproductive0.69611255
99MP0001440_abnormal_grooming_behavior0.69558013
100MP0005410_abnormal_fertilization0.68922687

Predicted human phenotypes

RankGene SetZ-score
1Congenital, generalized hypertrichosis (HP:0004540)3.78852810
2Congenital stationary night blindness (HP:0007642)3.62385606
3Abnormal number of erythroid precursors (HP:0012131)3.60979544
4Acute necrotizing encephalopathy (HP:0006965)3.58553458
5Visual hallucinations (HP:0002367)3.57883415
6Prostate neoplasm (HP:0100787)3.45901223
7Abnormality of cells of the erythroid lineage (HP:0012130)3.34956422
8Panhypogammaglobulinemia (HP:0003139)3.21985540
9Acute encephalopathy (HP:0006846)3.20170913
10Mitochondrial inheritance (HP:0001427)3.13130814
11Abnormal mitochondria in muscle tissue (HP:0008316)3.12166196
123-Methylglutaconic aciduria (HP:0003535)3.00581310
13Pancreatic cysts (HP:0001737)2.98267322
14Reticulocytopenia (HP:0001896)2.97821982
15Progressive macrocephaly (HP:0004481)2.94970861
16Molar tooth sign on MRI (HP:0002419)2.92520633
17Abnormality of midbrain morphology (HP:0002418)2.92520633
18Spastic diplegia (HP:0001264)2.89552834
19Testicular atrophy (HP:0000029)2.83272240
20Hepatocellular necrosis (HP:0001404)2.80722379
21Increased CSF lactate (HP:0002490)2.79116494
22Increased neuronal autofluorescent lipopigment (HP:0002074)2.67389526
23Opisthotonus (HP:0002179)2.65751429
24True hermaphroditism (HP:0010459)2.63201147
25Pancreatic fibrosis (HP:0100732)2.62456415
26Nephronophthisis (HP:0000090)2.61674517
27Asplenia (HP:0001746)2.51508888
28Abolished electroretinogram (ERG) (HP:0000550)2.46369817
29Aplasia/Hypoplasia of the spleen (HP:0010451)2.45653659
30Hepatic necrosis (HP:0002605)2.44169218
31Abnormality of the prostate (HP:0008775)2.44141517
32Short tibia (HP:0005736)2.40262025
33Abnormality of the phalanges of the 2nd finger (HP:0009541)2.40088398
34Methylmalonic acidemia (HP:0002912)2.38051151
35Hyperglycinemia (HP:0002154)2.34102298
36Cerebral edema (HP:0002181)2.33438478
37Aplasia/hypoplasia of the uterus (HP:0008684)2.32367972
38Optic disc pallor (HP:0000543)2.31175198
39Autoimmune thrombocytopenia (HP:0001973)2.30313182
40Abnormality of the pons (HP:0007361)2.30280335
41Thyroid-stimulating hormone excess (HP:0002925)2.25806791
42Abnormality of the renal cortex (HP:0011035)2.25263211
43Renal cortical cysts (HP:0000803)2.24941467
44Attenuation of retinal blood vessels (HP:0007843)2.24582688
45Macrocytic anemia (HP:0001972)2.24000475
46Abnormality of the renal medulla (HP:0100957)2.21758238
47Aplasia/Hypoplasia of the tibia (HP:0005772)2.21733038
48Meckel diverticulum (HP:0002245)2.19542477
49Abnormality of the renal collecting system (HP:0004742)2.18391182
50Aplasia/Hypoplasia of the hallux (HP:0008362)2.18376060
51Medial flaring of the eyebrow (HP:0010747)2.18178916
52Autoimmune hemolytic anemia (HP:0001890)2.17101536
53Hyperglycinuria (HP:0003108)2.16232780
54Duplicated collecting system (HP:0000081)2.15691260
55Increased hepatocellular lipid droplets (HP:0006565)2.15615066
56Abnormality of the proximal phalanges of the hand (HP:0009834)2.14688998
57Hypoplasia of the pons (HP:0012110)2.14678683
58Aplasia/Hypoplasia of the uvula (HP:0010293)2.12255729
59Abnormality of T cell physiology (HP:0011840)2.12072936
60B lymphocytopenia (HP:0010976)2.11833075
61Abnormality of B cell number (HP:0010975)2.10252961
62Hypoplasia of the uterus (HP:0000013)2.10056005
63Stomach cancer (HP:0012126)2.09648664
64Abnormality of the ileum (HP:0001549)2.09408401
65Lipid accumulation in hepatocytes (HP:0006561)2.08208393
66Increased serum lactate (HP:0002151)2.07471582
67Absent thumb (HP:0009777)2.03944678
68Sclerocornea (HP:0000647)2.03304163
69Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.01567558
70Symphalangism affecting the phalanges of the hand (HP:0009773)1.95267404
71Abnormal rod and cone electroretinograms (HP:0008323)1.94486898
72Abnormality of glycine metabolism (HP:0010895)1.94344557
73Abnormality of serine family amino acid metabolism (HP:0010894)1.94344557
74Optic nerve hypoplasia (HP:0000609)1.93919010
75Septo-optic dysplasia (HP:0100842)1.93419182
76Hypoproteinemia (HP:0003075)1.92824763
77Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.92718110
78Lethargy (HP:0001254)1.88443353
79Abnormality of purine metabolism (HP:0004352)1.87857352
80Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.87336685
81Short hallux (HP:0010109)1.86304165
82Furrowed tongue (HP:0000221)1.86276053
83Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.84039861
84Lactic acidosis (HP:0003128)1.83661278
85Increased cerebral lipofuscin (HP:0011813)1.83483247
86Abnormality of the fovea (HP:0000493)1.80433428
87Hypothermia (HP:0002045)1.79864599
88Decreased electroretinogram (ERG) amplitude (HP:0000654)1.79190012
89Conjunctival hamartoma (HP:0100780)1.78862154
90Pendular nystagmus (HP:0012043)1.78759924
91Gonadotropin excess (HP:0000837)1.74885070
92Abnormality of the phalanges of the 5th finger (HP:0004213)1.74422681
93Abnormality of the middle phalanges of the toes (HP:0010183)1.73862020
94Neutropenia (HP:0001875)1.70663639
95Triphalangeal thumb (HP:0001199)1.70099945
96Abnormality of the labia minora (HP:0012880)1.69253489
97Mesomelia (HP:0003027)1.68622276
98Abnormality of aspartate family amino acid metabolism (HP:0010899)1.67485683
99Type I transferrin isoform profile (HP:0003642)1.65879451
100Rimmed vacuoles (HP:0003805)1.65205682

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK23.98111278
2ZAK3.45896966
3MAP4K23.29175084
4BMPR1B3.07974524
5BCKDK2.76261514
6VRK12.71244240
7GRK12.62030664
8NUAK12.56898691
9BUB12.49757698
10TLK12.34268242
11CDK82.16646773
12KIT2.15320396
13ADRBK22.14105367
14TGFBR12.08507479
15TSSK62.02666997
16NME21.97261872
17TXK1.93442790
18NEK11.93308779
19MAP4K11.85931016
20MKNK11.68955433
21SRPK11.51710015
22PLK31.48758959
23WNK41.36161922
24WEE11.29886782
25STK161.27253015
26WNK31.14933887
27FRK1.13690403
28TAOK31.11934840
29PINK11.10924816
30MAP2K21.07858538
31PBK1.06746309
32CDC70.99563335
33INSRR0.94532057
34FLT30.93584877
35TRIM280.90815722
36RPS6KA40.90799856
37PNCK0.88531975
38PLK20.85396805
39IKBKB0.84025414
40MST40.82834783
41PASK0.81020123
42JAK30.80585006
43PLK40.78944560
44ATR0.77920941
45DYRK20.76720273
46TAF10.76457197
47ERBB30.76161785
48EPHB20.75240999
49SYK0.74740460
50CCNB10.71777031
51BMPR20.70905025
52LYN0.69634051
53CSNK1A10.68777240
54EIF2AK30.68209536
55RPS6KA50.67777867
56PLK10.67776594
57ACVR1B0.66392217
58MAPK130.65570305
59CHEK20.65307850
60OXSR10.64563461
61MAPK150.64134070
62AURKB0.63495165
63TIE10.61878394
64NME10.60837885
65OBSCN0.59954849
66CAMKK20.57378157
67CSNK1G20.56874056
68CSNK1G10.56575626
69CSNK1G30.55252468
70MAP2K70.55052203
71CSNK2A10.54915613
72EIF2AK20.54166552
73PRKCG0.53764157
74MAP3K40.51895538
75WNK10.51101728
76GRK60.48552542
77FES0.48546398
78TNIK0.48498214
79IKBKE0.47291736
80CSNK2A20.46965605
81CDK190.46429607
82BRSK20.44885444
83TTK0.44469242
84IGF1R0.44466128
85MAPKAPK50.43338303
86CSNK1A1L0.42297446
87PRKCE0.41214107
88PAK30.40322840
89GSK3A0.40063166
90DAPK10.40008899
91ADRBK10.39445696
92AURKA0.38505612
93PRKACA0.37077435
94CAMK2G0.36873969
95PHKG10.36325547
96PHKG20.36325547
97CDK30.36186922
98STK240.35894208
99ATM0.34227173
100DYRK30.33560518

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030103.90639394
2Asthma_Homo sapiens_hsa053103.63379216
3Proteasome_Homo sapiens_hsa030503.23363311
4Oxidative phosphorylation_Homo sapiens_hsa001903.08840645
5Parkinsons disease_Homo sapiens_hsa050122.67919127
6Intestinal immune network for IgA production_Homo sapiens_hsa046722.61210811
7Allograft rejection_Homo sapiens_hsa053302.49278108
8Homologous recombination_Homo sapiens_hsa034402.47791354
9Mismatch repair_Homo sapiens_hsa034302.35710819
10Autoimmune thyroid disease_Homo sapiens_hsa053202.26245431
11Protein export_Homo sapiens_hsa030602.11047931
12Spliceosome_Homo sapiens_hsa030402.10472357
13RNA degradation_Homo sapiens_hsa030182.08320013
14Fanconi anemia pathway_Homo sapiens_hsa034601.93041896
15RNA polymerase_Homo sapiens_hsa030201.90246626
16Graft-versus-host disease_Homo sapiens_hsa053321.89146650
17Basal transcription factors_Homo sapiens_hsa030221.84450304
18Type I diabetes mellitus_Homo sapiens_hsa049401.82488600
19Huntingtons disease_Homo sapiens_hsa050161.82176846
20Nucleotide excision repair_Homo sapiens_hsa034201.77608619
21One carbon pool by folate_Homo sapiens_hsa006701.69118582
22DNA replication_Homo sapiens_hsa030301.64866395
23Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.64090851
24Systemic lupus erythematosus_Homo sapiens_hsa053221.62905158
25Nitrogen metabolism_Homo sapiens_hsa009101.60488877
26Antigen processing and presentation_Homo sapiens_hsa046121.59848943
27Alzheimers disease_Homo sapiens_hsa050101.59164445
28Phototransduction_Homo sapiens_hsa047441.57708022
29Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.54900446
30Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.47065792
31Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.46156118
32Cardiac muscle contraction_Homo sapiens_hsa042601.41108390
33Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.29834913
34Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.24864969
35Purine metabolism_Homo sapiens_hsa002301.17993920
36Propanoate metabolism_Homo sapiens_hsa006401.13915682
37RNA transport_Homo sapiens_hsa030131.12708481
38Non-homologous end-joining_Homo sapiens_hsa034501.08620937
39Linoleic acid metabolism_Homo sapiens_hsa005911.05344169
40Sulfur metabolism_Homo sapiens_hsa009201.04833867
41Selenocompound metabolism_Homo sapiens_hsa004501.01690125
42Primary immunodeficiency_Homo sapiens_hsa053401.01279047
43Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.98237801
44Base excision repair_Homo sapiens_hsa034100.97001200
45Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.89114072
46Pyrimidine metabolism_Homo sapiens_hsa002400.88366838
47Cyanoamino acid metabolism_Homo sapiens_hsa004600.86075379
48Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.85592447
49Tryptophan metabolism_Homo sapiens_hsa003800.84413514
50Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.83456538
51Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.82904385
52Cysteine and methionine metabolism_Homo sapiens_hsa002700.79527564
53Ether lipid metabolism_Homo sapiens_hsa005650.78624499
54Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.76312310
55Rheumatoid arthritis_Homo sapiens_hsa053230.73578736
56Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.71884174
57Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.71732774
58Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.71375934
59Staphylococcus aureus infection_Homo sapiens_hsa051500.69304638
60Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.68742909
61Maturity onset diabetes of the young_Homo sapiens_hsa049500.66155778
62alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.65631037
63Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.60771683
64Olfactory transduction_Homo sapiens_hsa047400.59507711
65Vitamin digestion and absorption_Homo sapiens_hsa049770.58584568
66Caffeine metabolism_Homo sapiens_hsa002320.54545856
67Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.53945803
68Chemical carcinogenesis_Homo sapiens_hsa052040.52240601
69Fatty acid elongation_Homo sapiens_hsa000620.51779396
70Butanoate metabolism_Homo sapiens_hsa006500.51135182
71Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.49983260
72Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.49327803
73Steroid hormone biosynthesis_Homo sapiens_hsa001400.49119832
74Alcoholism_Homo sapiens_hsa050340.48339997
75Arachidonic acid metabolism_Homo sapiens_hsa005900.47482558
76Regulation of autophagy_Homo sapiens_hsa041400.46574177
77Metabolic pathways_Homo sapiens_hsa011000.45882419
78Leishmaniasis_Homo sapiens_hsa051400.44445171
79Peroxisome_Homo sapiens_hsa041460.44415442
80Viral myocarditis_Homo sapiens_hsa054160.43479033
81Retinol metabolism_Homo sapiens_hsa008300.41244816
82Taste transduction_Homo sapiens_hsa047420.40167592
83Hedgehog signaling pathway_Homo sapiens_hsa043400.39202775
84Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.37632103
85Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.37199258
86Hematopoietic cell lineage_Homo sapiens_hsa046400.36758714
87Steroid biosynthesis_Homo sapiens_hsa001000.35345451
88mRNA surveillance pathway_Homo sapiens_hsa030150.34823638
89Circadian entrainment_Homo sapiens_hsa047130.31362347
90Basal cell carcinoma_Homo sapiens_hsa052170.31252332
91Herpes simplex infection_Homo sapiens_hsa051680.29628968
92Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.29596204
93Glutathione metabolism_Homo sapiens_hsa004800.28392202
94Cell cycle_Homo sapiens_hsa041100.26119168
95p53 signaling pathway_Homo sapiens_hsa041150.26069557
96Fat digestion and absorption_Homo sapiens_hsa049750.24155857
97Pyruvate metabolism_Homo sapiens_hsa006200.23554013
98Fatty acid degradation_Homo sapiens_hsa000710.23536677
99Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.23502900
100Nicotine addiction_Homo sapiens_hsa050330.22081486

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »