

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 5.41010820 |
| 2 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.32120705 |
| 3 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 5.02762681 |
| 4 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 5.02762681 |
| 5 | NADH dehydrogenase complex assembly (GO:0010257) | 5.02762681 |
| 6 | chaperone-mediated protein transport (GO:0072321) | 4.83155664 |
| 7 | protein complex biogenesis (GO:0070271) | 4.35455784 |
| 8 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.29951976 |
| 9 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.27269021 |
| 10 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.27269021 |
| 11 | protein deneddylation (GO:0000338) | 4.06060252 |
| 12 | ATP synthesis coupled proton transport (GO:0015986) | 4.05993721 |
| 13 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.05993721 |
| 14 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.90298857 |
| 15 | fucose catabolic process (GO:0019317) | 3.84170750 |
| 16 | L-fucose metabolic process (GO:0042354) | 3.84170750 |
| 17 | L-fucose catabolic process (GO:0042355) | 3.84170750 |
| 18 | negative regulation of mast cell activation (GO:0033004) | 3.69836131 |
| 19 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.69602283 |
| 20 | cullin deneddylation (GO:0010388) | 3.68538915 |
| 21 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.65529217 |
| 22 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.60108202 |
| 23 | platelet dense granule organization (GO:0060155) | 3.38875562 |
| 24 | pseudouridine synthesis (GO:0001522) | 3.38471703 |
| 25 | maturation of 5.8S rRNA (GO:0000460) | 3.30994600 |
| 26 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.29629683 |
| 27 | protein neddylation (GO:0045116) | 3.28812232 |
| 28 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.24643844 |
| 29 | negative regulation of telomere maintenance (GO:0032205) | 3.23594696 |
| 30 | respiratory chain complex IV assembly (GO:0008535) | 3.22778088 |
| 31 | proteasome assembly (GO:0043248) | 3.17370570 |
| 32 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.16821157 |
| 33 | isotype switching (GO:0045190) | 3.16821157 |
| 34 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.16821157 |
| 35 | somatic diversification of immunoglobulins (GO:0016445) | 3.13143596 |
| 36 | maturation of SSU-rRNA (GO:0030490) | 3.10176385 |
| 37 | positive regulation of oligodendrocyte differentiation (GO:0048714) | 3.08430429 |
| 38 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.05920627 |
| 39 | ubiquinone metabolic process (GO:0006743) | 3.02730761 |
| 40 | termination of RNA polymerase I transcription (GO:0006363) | 3.00071625 |
| 41 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.99004486 |
| 42 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.99004486 |
| 43 | DNA damage response, detection of DNA damage (GO:0042769) | 2.98195119 |
| 44 | protein-cofactor linkage (GO:0018065) | 2.98141775 |
| 45 | somatic recombination of immunoglobulin gene segments (GO:0016447) | 2.96733259 |
| 46 | termination of RNA polymerase III transcription (GO:0006386) | 2.94975963 |
| 47 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.94975963 |
| 48 | GTP biosynthetic process (GO:0006183) | 2.94911752 |
| 49 | tRNA processing (GO:0008033) | 2.93062979 |
| 50 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.91173505 |
| 51 | ubiquinone biosynthetic process (GO:0006744) | 2.85228225 |
| 52 | somite development (GO:0061053) | 2.81788461 |
| 53 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.81575940 |
| 54 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.81575940 |
| 55 | rRNA metabolic process (GO:0016072) | 2.80770712 |
| 56 | rRNA processing (GO:0006364) | 2.79619264 |
| 57 | electron transport chain (GO:0022900) | 2.78198496 |
| 58 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.77645220 |
| 59 | respiratory electron transport chain (GO:0022904) | 2.76519687 |
| 60 | inner mitochondrial membrane organization (GO:0007007) | 2.70465474 |
| 61 | response to pheromone (GO:0019236) | 2.70215613 |
| 62 | intracellular protein transmembrane import (GO:0044743) | 2.69655257 |
| 63 | protein localization to mitochondrion (GO:0070585) | 2.69646743 |
| 64 | aggressive behavior (GO:0002118) | 2.65836421 |
| 65 | protein targeting to mitochondrion (GO:0006626) | 2.64553387 |
| 66 | gamma-aminobutyric acid transport (GO:0015812) | 2.63792291 |
| 67 | ribosomal small subunit assembly (GO:0000028) | 2.63221122 |
| 68 | mannosylation (GO:0097502) | 2.62757509 |
| 69 | rRNA modification (GO:0000154) | 2.62653626 |
| 70 | tRNA metabolic process (GO:0006399) | 2.60929860 |
| 71 | establishment of protein localization to mitochondrion (GO:0072655) | 2.60729195 |
| 72 | telomere maintenance via telomerase (GO:0007004) | 2.58146329 |
| 73 | somatic diversification of immune receptors (GO:0002200) | 2.56717258 |
| 74 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.55227182 |
| 75 | UTP biosynthetic process (GO:0006228) | 2.54858426 |
| 76 | regulation of timing of cell differentiation (GO:0048505) | 2.54069986 |
| 77 | ncRNA processing (GO:0034470) | 2.51869538 |
| 78 | rRNA catabolic process (GO:0016075) | 2.51714689 |
| 79 | ncRNA metabolic process (GO:0034660) | 2.51018554 |
| 80 | cellular component biogenesis (GO:0044085) | 2.50923839 |
| 81 | opioid receptor signaling pathway (GO:0038003) | 2.49381501 |
| 82 | positive regulation of mitochondrial fission (GO:0090141) | 2.49015357 |
| 83 | kynurenine metabolic process (GO:0070189) | 2.48803719 |
| 84 | spliceosomal snRNP assembly (GO:0000387) | 2.48033745 |
| 85 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.47956159 |
| 86 | transcription from RNA polymerase I promoter (GO:0006360) | 2.47620375 |
| 87 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.47506402 |
| 88 | UTP metabolic process (GO:0046051) | 2.47388701 |
| 89 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.45859955 |
| 90 | behavioral response to nicotine (GO:0035095) | 2.44676073 |
| 91 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.42461996 |
| 92 | replication fork processing (GO:0031297) | 2.41222276 |
| 93 | somatic cell DNA recombination (GO:0016444) | 2.40150084 |
| 94 | somatic diversification of immune receptors via germline recombination within a single locus (GO:000 | 2.40150084 |
| 95 | cardiac left ventricle morphogenesis (GO:0003214) | 2.39772394 |
| 96 | indole-containing compound catabolic process (GO:0042436) | 2.39691447 |
| 97 | indolalkylamine catabolic process (GO:0046218) | 2.39691447 |
| 98 | tryptophan catabolic process (GO:0006569) | 2.39691447 |
| 99 | regulation of germinal center formation (GO:0002634) | 2.39523496 |
| 100 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.38630150 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.64504652 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.12016892 |
| 3 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 4.00665230 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.32492960 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.09511813 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.08507697 |
| 7 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.02976686 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.61797003 |
| 9 | EWS_26573619_Chip-Seq_HEK293_Human | 2.46385050 |
| 10 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.46060729 |
| 11 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.42683070 |
| 12 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.40927305 |
| 13 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.40440285 |
| 14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.35990109 |
| 15 | FUS_26573619_Chip-Seq_HEK293_Human | 2.22073066 |
| 16 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.20353953 |
| 17 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.19730520 |
| 18 | VDR_22108803_ChIP-Seq_LS180_Human | 2.11596781 |
| 19 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.07475661 |
| 20 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.06682491 |
| 21 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.03299119 |
| 22 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.91809768 |
| 23 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.86205370 |
| 24 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.85170856 |
| 25 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.84254625 |
| 26 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.81636655 |
| 27 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.72959720 |
| 28 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.71671423 |
| 29 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.71651816 |
| 30 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.70896684 |
| 31 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.70807769 |
| 32 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.67382477 |
| 33 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.58530582 |
| 34 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.52876070 |
| 35 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.50867825 |
| 36 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.49738595 |
| 37 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.48916831 |
| 38 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.48915075 |
| 39 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.48729301 |
| 40 | P300_19829295_ChIP-Seq_ESCs_Human | 1.48102886 |
| 41 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.45974817 |
| 42 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.43920047 |
| 43 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.42786656 |
| 44 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.42005835 |
| 45 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.34597421 |
| 46 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.33561132 |
| 47 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.32794075 |
| 48 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.30716151 |
| 49 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.27854335 |
| 50 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.24587914 |
| 51 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.24361240 |
| 52 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.23712034 |
| 53 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.23690641 |
| 54 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.23080731 |
| 55 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.19017412 |
| 56 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.17643094 |
| 57 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.15199499 |
| 58 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.14869508 |
| 59 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.14869508 |
| 60 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.14530768 |
| 61 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.13620429 |
| 62 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.12653418 |
| 63 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.12653418 |
| 64 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.10464575 |
| 65 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.09128740 |
| 66 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.09128740 |
| 67 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.06776193 |
| 68 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.06396488 |
| 69 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.05631415 |
| 70 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.04528005 |
| 71 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.04175509 |
| 72 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.03619873 |
| 73 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.03532516 |
| 74 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.01577474 |
| 75 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.98256877 |
| 76 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.98174973 |
| 77 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.98016206 |
| 78 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.97414218 |
| 79 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.96007853 |
| 80 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.94964277 |
| 81 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.94507107 |
| 82 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.93929596 |
| 83 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.93000996 |
| 84 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.92576624 |
| 85 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.92433989 |
| 86 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.92258278 |
| 87 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.92258278 |
| 88 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.91936787 |
| 89 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.91792449 |
| 90 | GATA3_26560356_Chip-Seq_TH2_Human | 0.90574512 |
| 91 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.89703800 |
| 92 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.88803818 |
| 93 | AR_20517297_ChIP-Seq_VCAP_Human | 0.86859169 |
| 94 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.86809265 |
| 95 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.85472501 |
| 96 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.84826795 |
| 97 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.84460977 |
| 98 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.83073503 |
| 99 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.82700092 |
| 100 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.82466942 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002102_abnormal_ear_morphology | 3.67376187 |
| 2 | MP0002138_abnormal_hepatobiliary_system | 3.45101682 |
| 3 | MP0006072_abnormal_retinal_apoptosis | 2.87806797 |
| 4 | MP0005646_abnormal_pituitary_gland | 2.50475082 |
| 5 | MP0008058_abnormal_DNA_repair | 2.44598404 |
| 6 | MP0003567_abnormal_fetal_cardiomyocyte | 2.40443516 |
| 7 | MP0002837_dystrophic_cardiac_calcinosis | 2.24062559 |
| 8 | MP0004133_heterotaxia | 2.15867980 |
| 9 | MP0000566_synostosis | 2.13251757 |
| 10 | MP0008875_abnormal_xenobiotic_pharmacok | 2.11797469 |
| 11 | MP0008872_abnormal_physiological_respon | 2.09483470 |
| 12 | MP0003693_abnormal_embryo_hatching | 2.09480481 |
| 13 | MP0001348_abnormal_lacrimal_gland | 2.06825964 |
| 14 | MP0003786_premature_aging | 1.99422288 |
| 15 | MP0008877_abnormal_DNA_methylation | 1.98913407 |
| 16 | MP0008789_abnormal_olfactory_epithelium | 1.97637341 |
| 17 | MP0006292_abnormal_olfactory_placode | 1.86851597 |
| 18 | MP0005084_abnormal_gallbladder_morpholo | 1.83789724 |
| 19 | MP0008995_early_reproductive_senescence | 1.77788035 |
| 20 | MP0003718_maternal_effect | 1.74128919 |
| 21 | MP0002277_abnormal_respiratory_mucosa | 1.74021690 |
| 22 | MP0000372_irregular_coat_pigmentation | 1.73933741 |
| 23 | MP0001968_abnormal_touch/_nociception | 1.73518951 |
| 24 | MP0005551_abnormal_eye_electrophysiolog | 1.71576662 |
| 25 | MP0000383_abnormal_hair_follicle | 1.67590851 |
| 26 | MP0004142_abnormal_muscle_tone | 1.67104267 |
| 27 | MP0001293_anophthalmia | 1.66803056 |
| 28 | MP0005394_taste/olfaction_phenotype | 1.64821433 |
| 29 | MP0005499_abnormal_olfactory_system | 1.64821433 |
| 30 | MP0003806_abnormal_nucleotide_metabolis | 1.59705800 |
| 31 | MP0001485_abnormal_pinna_reflex | 1.54657362 |
| 32 | MP0003195_calcinosis | 1.54430163 |
| 33 | MP0005671_abnormal_response_to | 1.53763504 |
| 34 | MP0006276_abnormal_autonomic_nervous | 1.53194913 |
| 35 | MP0003283_abnormal_digestive_organ | 1.47515055 |
| 36 | MP0004145_abnormal_muscle_electrophysio | 1.46316291 |
| 37 | MP0005253_abnormal_eye_physiology | 1.45916950 |
| 38 | MP0001501_abnormal_sleep_pattern | 1.40001355 |
| 39 | MP0000685_abnormal_immune_system | 1.36736104 |
| 40 | MP0003878_abnormal_ear_physiology | 1.36233324 |
| 41 | MP0005377_hearing/vestibular/ear_phenot | 1.36233324 |
| 42 | MP0002272_abnormal_nervous_system | 1.34696341 |
| 43 | MP0004885_abnormal_endolymph | 1.30805134 |
| 44 | MP0000631_abnormal_neuroendocrine_gland | 1.30496286 |
| 45 | MP0001486_abnormal_startle_reflex | 1.29588430 |
| 46 | MP0000569_abnormal_digit_pigmentation | 1.28263336 |
| 47 | MP0003011_delayed_dark_adaptation | 1.28036661 |
| 48 | MP0001984_abnormal_olfaction | 1.27972442 |
| 49 | MP0000049_abnormal_middle_ear | 1.25747754 |
| 50 | MP0002638_abnormal_pupillary_reflex | 1.24026181 |
| 51 | MP0001529_abnormal_vocalization | 1.19269068 |
| 52 | MP0004147_increased_porphyrin_level | 1.18208233 |
| 53 | MP0009745_abnormal_behavioral_response | 1.18187641 |
| 54 | MP0001835_abnormal_antigen_presentation | 1.17458774 |
| 55 | MP0005085_abnormal_gallbladder_physiolo | 1.15429097 |
| 56 | MP0003937_abnormal_limbs/digits/tail_de | 1.15399385 |
| 57 | MP0001764_abnormal_homeostasis | 1.14015109 |
| 58 | MP0005410_abnormal_fertilization | 1.12123794 |
| 59 | MP0003880_abnormal_central_pattern | 1.11360739 |
| 60 | MP0005389_reproductive_system_phenotype | 1.09690145 |
| 61 | MP0003119_abnormal_digestive_system | 1.08462293 |
| 62 | MP0002006_tumorigenesis | 1.08111187 |
| 63 | MP0002736_abnormal_nociception_after | 1.07193023 |
| 64 | MP0002751_abnormal_autonomic_nervous | 1.05657776 |
| 65 | MP0002938_white_spotting | 1.03268726 |
| 66 | MP0002822_catalepsy | 1.00669564 |
| 67 | MP0005310_abnormal_salivary_gland | 1.00142217 |
| 68 | MP0004742_abnormal_vestibular_system | 0.96375532 |
| 69 | MP0006036_abnormal_mitochondrial_physio | 0.95601374 |
| 70 | MP0009046_muscle_twitch | 0.93304124 |
| 71 | MP0002160_abnormal_reproductive_system | 0.93053440 |
| 72 | MP0002234_abnormal_pharynx_morphology | 0.92522226 |
| 73 | MP0005379_endocrine/exocrine_gland_phen | 0.91187121 |
| 74 | MP0010386_abnormal_urinary_bladder | 0.91026786 |
| 75 | MP0003938_abnormal_ear_development | 0.90955455 |
| 76 | MP0010094_abnormal_chromosome_stability | 0.89521358 |
| 77 | MP0002166_altered_tumor_susceptibility | 0.87562175 |
| 78 | MP0002233_abnormal_nose_morphology | 0.84232264 |
| 79 | MP0002557_abnormal_social/conspecific_i | 0.82961646 |
| 80 | MP0001919_abnormal_reproductive_system | 0.82653966 |
| 81 | MP0000613_abnormal_salivary_gland | 0.82563537 |
| 82 | MP0003890_abnormal_embryonic-extraembry | 0.79668859 |
| 83 | MP0010678_abnormal_skin_adnexa | 0.77159828 |
| 84 | MP0005195_abnormal_posterior_eye | 0.76652646 |
| 85 | MP0003646_muscle_fatigue | 0.74972875 |
| 86 | MP0000026_abnormal_inner_ear | 0.74055240 |
| 87 | MP0001188_hyperpigmentation | 0.73735176 |
| 88 | MP0002282_abnormal_trachea_morphology | 0.72975980 |
| 89 | MP0001800_abnormal_humoral_immune | 0.68088194 |
| 90 | MP0002733_abnormal_thermal_nociception | 0.68024094 |
| 91 | MP0002572_abnormal_emotion/affect_behav | 0.67800139 |
| 92 | MP0001119_abnormal_female_reproductive | 0.66585173 |
| 93 | MP0001905_abnormal_dopamine_level | 0.65489729 |
| 94 | MP0000647_abnormal_sebaceous_gland | 0.65446148 |
| 95 | MP0001970_abnormal_pain_threshold | 0.64892523 |
| 96 | MP0009053_abnormal_anal_canal | 0.64446406 |
| 97 | MP0005391_vision/eye_phenotype | 0.63349384 |
| 98 | MP0002752_abnormal_somatic_nervous | 0.62452789 |
| 99 | MP0001790_abnormal_immune_system | 0.62163641 |
| 100 | MP0005387_immune_system_phenotype | 0.62163641 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.46858062 |
| 2 | Congenital stationary night blindness (HP:0007642) | 4.07392726 |
| 3 | Acute encephalopathy (HP:0006846) | 3.86540784 |
| 4 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.84607068 |
| 5 | Progressive macrocephaly (HP:0004481) | 3.82792922 |
| 6 | Mitochondrial inheritance (HP:0001427) | 3.49449988 |
| 7 | Increased CSF lactate (HP:0002490) | 3.25027093 |
| 8 | Abnormality of midbrain morphology (HP:0002418) | 3.21583124 |
| 9 | Molar tooth sign on MRI (HP:0002419) | 3.21583124 |
| 10 | Methylmalonic acidemia (HP:0002912) | 3.06097676 |
| 11 | IgG deficiency (HP:0004315) | 3.00773992 |
| 12 | Congenital, generalized hypertrichosis (HP:0004540) | 2.98135142 |
| 13 | Pancreatic cysts (HP:0001737) | 2.91919631 |
| 14 | Hepatocellular necrosis (HP:0001404) | 2.91774978 |
| 15 | Type 2 muscle fiber atrophy (HP:0003554) | 2.88687361 |
| 16 | Fibular aplasia (HP:0002990) | 2.82345126 |
| 17 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 2.78015424 |
| 18 | 3-Methylglutaconic aciduria (HP:0003535) | 2.77253692 |
| 19 | Renal cortical cysts (HP:0000803) | 2.72950536 |
| 20 | Nephronophthisis (HP:0000090) | 2.72170509 |
| 21 | Cerebral edema (HP:0002181) | 2.68457116 |
| 22 | Hypomagnesemia (HP:0002917) | 2.67978504 |
| 23 | Hepatic necrosis (HP:0002605) | 2.67817309 |
| 24 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.65459408 |
| 25 | Pancreatic fibrosis (HP:0100732) | 2.58683619 |
| 26 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.57272552 |
| 27 | Meckel diverticulum (HP:0002245) | 2.53481854 |
| 28 | True hermaphroditism (HP:0010459) | 2.53200367 |
| 29 | Abolished electroretinogram (ERG) (HP:0000550) | 2.51152139 |
| 30 | Abnormal biliary tract physiology (HP:0012439) | 2.50372163 |
| 31 | Bile duct proliferation (HP:0001408) | 2.50372163 |
| 32 | Abnormality of the ileum (HP:0001549) | 2.47570027 |
| 33 | Pendular nystagmus (HP:0012043) | 2.47460457 |
| 34 | Hypoplasia of the uterus (HP:0000013) | 2.42021061 |
| 35 | Abnormality of the renal medulla (HP:0100957) | 2.38064709 |
| 36 | Hyperglycinemia (HP:0002154) | 2.37348500 |
| 37 | Methylmalonic aciduria (HP:0012120) | 2.35956930 |
| 38 | Humeroradial synostosis (HP:0003041) | 2.34848884 |
| 39 | Synostosis involving the elbow (HP:0003938) | 2.34848884 |
| 40 | Increased serum lactate (HP:0002151) | 2.34777078 |
| 41 | Abnormality of the renal cortex (HP:0011035) | 2.29878868 |
| 42 | Muscle fiber atrophy (HP:0100295) | 2.28272389 |
| 43 | Lactic acidosis (HP:0003128) | 2.28045284 |
| 44 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.26353718 |
| 45 | Hypothermia (HP:0002045) | 2.26236094 |
| 46 | Fused cervical vertebrae (HP:0002949) | 2.23947281 |
| 47 | Intestinal atresia (HP:0011100) | 2.23944003 |
| 48 | Optic disc pallor (HP:0000543) | 2.22803848 |
| 49 | Prostate neoplasm (HP:0100787) | 2.21567541 |
| 50 | Abnormality of the middle phalanges of the toes (HP:0010183) | 2.17727572 |
| 51 | Asplenia (HP:0001746) | 2.17254157 |
| 52 | Increased hepatocellular lipid droplets (HP:0006565) | 2.16553110 |
| 53 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.15814987 |
| 54 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.15727719 |
| 55 | Respiratory failure (HP:0002878) | 2.15141232 |
| 56 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.12022668 |
| 57 | Leukodystrophy (HP:0002415) | 2.08548430 |
| 58 | Hypoplasia of the pons (HP:0012110) | 2.06311090 |
| 59 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.00630758 |
| 60 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.99491510 |
| 61 | Inability to walk (HP:0002540) | 1.98205104 |
| 62 | Stomatitis (HP:0010280) | 1.97581874 |
| 63 | Abnormality of magnesium homeostasis (HP:0004921) | 1.96718227 |
| 64 | Oral leukoplakia (HP:0002745) | 1.96674665 |
| 65 | Short 1st metacarpal (HP:0010034) | 1.96604644 |
| 66 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 1.96604644 |
| 67 | Progressive inability to walk (HP:0002505) | 1.96108291 |
| 68 | Abnormality of the pons (HP:0007361) | 1.93905447 |
| 69 | Aplastic anemia (HP:0001915) | 1.93568912 |
| 70 | Bilateral microphthalmos (HP:0007633) | 1.93267403 |
| 71 | Abnormality of the neuromuscular junction (HP:0003398) | 1.89752175 |
| 72 | Fatigable weakness (HP:0003473) | 1.89752175 |
| 73 | Reduced antithrombin III activity (HP:0001976) | 1.88816553 |
| 74 | Abnormality of the prostate (HP:0008775) | 1.87906649 |
| 75 | Supernumerary spleens (HP:0009799) | 1.87394821 |
| 76 | Atonic seizures (HP:0010819) | 1.87289345 |
| 77 | Opisthotonus (HP:0002179) | 1.86827933 |
| 78 | Lethargy (HP:0001254) | 1.81830864 |
| 79 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 1.81536290 |
| 80 | Hypoplasia of the fovea (HP:0007750) | 1.81230822 |
| 81 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.81230822 |
| 82 | Lipid accumulation in hepatocytes (HP:0006561) | 1.80907613 |
| 83 | Abnormality of the 1st metacarpal (HP:0010009) | 1.78170458 |
| 84 | Adactyly (HP:0009776) | 1.77627130 |
| 85 | Polyuria (HP:0000103) | 1.77113568 |
| 86 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.77042946 |
| 87 | Abnormality of glycine metabolism (HP:0010895) | 1.77042946 |
| 88 | Severe combined immunodeficiency (HP:0004430) | 1.76904240 |
| 89 | Brittle hair (HP:0002299) | 1.76489919 |
| 90 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.75126959 |
| 91 | Volvulus (HP:0002580) | 1.74856467 |
| 92 | Colon cancer (HP:0003003) | 1.73870966 |
| 93 | Gonadotropin excess (HP:0000837) | 1.71613209 |
| 94 | Gaze-evoked nystagmus (HP:0000640) | 1.71448923 |
| 95 | Exercise intolerance (HP:0003546) | 1.70884034 |
| 96 | Short hallux (HP:0010109) | 1.69249042 |
| 97 | Palpitations (HP:0001962) | 1.68969846 |
| 98 | Abnormality of the pulmonary veins (HP:0011718) | 1.68595245 |
| 99 | Renal Fanconi syndrome (HP:0001994) | 1.68456471 |
| 100 | Multiple enchondromatosis (HP:0005701) | 1.67378501 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K2 | 4.01425292 |
| 2 | PINK1 | 3.41376500 |
| 3 | TSSK6 | 3.20827817 |
| 4 | VRK2 | 2.97585328 |
| 5 | TXK | 2.81623114 |
| 6 | ADRBK2 | 2.71335794 |
| 7 | NME1 | 2.57762453 |
| 8 | NUAK1 | 2.44381736 |
| 9 | WNK3 | 2.34366403 |
| 10 | ZAK | 2.33035304 |
| 11 | MKNK1 | 2.30970177 |
| 12 | FRK | 2.24613701 |
| 13 | EIF2AK1 | 2.21871408 |
| 14 | PBK | 2.18825149 |
| 15 | TAOK3 | 2.16702342 |
| 16 | TAF1 | 2.14877279 |
| 17 | EIF2AK3 | 2.13191547 |
| 18 | MST4 | 2.07257953 |
| 19 | TLK1 | 2.03034911 |
| 20 | SRPK1 | 1.94366174 |
| 21 | GRK1 | 1.90533132 |
| 22 | VRK1 | 1.82356514 |
| 23 | PLK2 | 1.59940725 |
| 24 | MKNK2 | 1.46677567 |
| 25 | TNIK | 1.46670263 |
| 26 | PLK3 | 1.41306082 |
| 27 | PLK4 | 1.36659330 |
| 28 | MAPKAPK3 | 1.29478592 |
| 29 | MAPKAPK5 | 1.28560689 |
| 30 | KIT | 1.16213980 |
| 31 | MAP4K1 | 1.15534014 |
| 32 | WNK4 | 1.11830517 |
| 33 | BCR | 1.10746571 |
| 34 | CDC7 | 1.10427967 |
| 35 | DYRK2 | 1.05619651 |
| 36 | TRIM28 | 1.02327576 |
| 37 | BCKDK | 1.01491124 |
| 38 | BUB1 | 0.99696070 |
| 39 | OXSR1 | 0.98847725 |
| 40 | PHKG2 | 0.98371256 |
| 41 | PHKG1 | 0.98371256 |
| 42 | BMPR1B | 0.96577672 |
| 43 | PASK | 0.95243417 |
| 44 | MAPK13 | 0.95064887 |
| 45 | RPS6KA5 | 0.90104547 |
| 46 | STK39 | 0.83967099 |
| 47 | STK16 | 0.81109924 |
| 48 | TNK2 | 0.79902076 |
| 49 | NEK1 | 0.76929649 |
| 50 | CSNK1G2 | 0.71887214 |
| 51 | RPS6KA4 | 0.71400201 |
| 52 | TAOK1 | 0.71317402 |
| 53 | EIF2AK2 | 0.71254243 |
| 54 | INSRR | 0.67323855 |
| 55 | PRKCE | 0.66363870 |
| 56 | MATK | 0.65095252 |
| 57 | TIE1 | 0.63890139 |
| 58 | CAMK2A | 0.63426398 |
| 59 | ALK | 0.58765170 |
| 60 | ITK | 0.57725432 |
| 61 | AURKB | 0.57592171 |
| 62 | CSNK1G1 | 0.57526422 |
| 63 | PRKCG | 0.54428124 |
| 64 | TGFBR1 | 0.53297050 |
| 65 | EPHA4 | 0.51860702 |
| 66 | CDK3 | 0.50918682 |
| 67 | DYRK3 | 0.49944863 |
| 68 | CSNK1G3 | 0.49041096 |
| 69 | SYK | 0.47436255 |
| 70 | LYN | 0.46660003 |
| 71 | WEE1 | 0.46315945 |
| 72 | IKBKE | 0.46051464 |
| 73 | IKBKB | 0.45384646 |
| 74 | PLK1 | 0.44426062 |
| 75 | CSNK1A1 | 0.44067736 |
| 76 | CSNK2A1 | 0.43450618 |
| 77 | MAP2K2 | 0.41827212 |
| 78 | GRK6 | 0.41205098 |
| 79 | DAPK1 | 0.40746703 |
| 80 | GRK5 | 0.40661413 |
| 81 | ATR | 0.40481348 |
| 82 | CSNK1E | 0.40013575 |
| 83 | CSNK2A2 | 0.39961392 |
| 84 | TTK | 0.39792576 |
| 85 | PNCK | 0.38616435 |
| 86 | PIK3CG | 0.38319831 |
| 87 | CDK8 | 0.37769577 |
| 88 | CSNK1A1L | 0.36567905 |
| 89 | CAMK2B | 0.36479762 |
| 90 | NEK9 | 0.35879891 |
| 91 | TEC | 0.35461783 |
| 92 | PRKCQ | 0.34380249 |
| 93 | NME2 | 0.33936870 |
| 94 | ADRBK1 | 0.33070907 |
| 95 | PRKACA | 0.32747261 |
| 96 | FLT3 | 0.31915278 |
| 97 | ERBB3 | 0.31735998 |
| 98 | MUSK | 0.31327584 |
| 99 | ERBB2 | 0.29522412 |
| 100 | PRKCI | 0.29459774 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 3.20510700 |
| 2 | Asthma_Homo sapiens_hsa05310 | 2.97025125 |
| 3 | RNA polymerase_Homo sapiens_hsa03020 | 2.76511050 |
| 4 | Protein export_Homo sapiens_hsa03060 | 2.68893528 |
| 5 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.66295592 |
| 6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.58073769 |
| 7 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.54338875 |
| 8 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.52067915 |
| 9 | Ribosome_Homo sapiens_hsa03010 | 2.33906851 |
| 10 | Parkinsons disease_Homo sapiens_hsa05012 | 2.32388610 |
| 11 | Allograft rejection_Homo sapiens_hsa05330 | 2.11772435 |
| 12 | Basal transcription factors_Homo sapiens_hsa03022 | 1.98954967 |
| 13 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.98184601 |
| 14 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.94297809 |
| 15 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.92401031 |
| 16 | RNA degradation_Homo sapiens_hsa03018 | 1.86581684 |
| 17 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.77885733 |
| 18 | Mismatch repair_Homo sapiens_hsa03430 | 1.76421217 |
| 19 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.67363527 |
| 20 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.61251067 |
| 21 | Huntingtons disease_Homo sapiens_hsa05016 | 1.55567437 |
| 22 | Homologous recombination_Homo sapiens_hsa03440 | 1.53040850 |
| 23 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.51047573 |
| 24 | Phototransduction_Homo sapiens_hsa04744 | 1.44963157 |
| 25 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.43653771 |
| 26 | RNA transport_Homo sapiens_hsa03013 | 1.41608787 |
| 27 | Alzheimers disease_Homo sapiens_hsa05010 | 1.35007202 |
| 28 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.34729045 |
| 29 | Nicotine addiction_Homo sapiens_hsa05033 | 1.33623093 |
| 30 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.33057943 |
| 31 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.30338083 |
| 32 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.26882701 |
| 33 | Spliceosome_Homo sapiens_hsa03040 | 1.26837045 |
| 34 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.26424719 |
| 35 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.25922722 |
| 36 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.25832626 |
| 37 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.25004897 |
| 38 | DNA replication_Homo sapiens_hsa03030 | 1.24839728 |
| 39 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.23902707 |
| 40 | Purine metabolism_Homo sapiens_hsa00230 | 1.23188683 |
| 41 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.20173220 |
| 42 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.15562879 |
| 43 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.13772709 |
| 44 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.13413730 |
| 45 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.09236208 |
| 46 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.04117230 |
| 47 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.03217294 |
| 48 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.01888775 |
| 49 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.01553084 |
| 50 | Base excision repair_Homo sapiens_hsa03410 | 1.00327748 |
| 51 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.00115539 |
| 52 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.99459881 |
| 53 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.98694734 |
| 54 | Taste transduction_Homo sapiens_hsa04742 | 0.98173758 |
| 55 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.97316688 |
| 56 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.97225081 |
| 57 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.96838077 |
| 58 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.93567564 |
| 59 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.92758309 |
| 60 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.92428803 |
| 61 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.82503921 |
| 62 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.82035054 |
| 63 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.81559811 |
| 64 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.77887124 |
| 65 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.77352842 |
| 66 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.77299262 |
| 67 | Peroxisome_Homo sapiens_hsa04146 | 0.74108157 |
| 68 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.70722186 |
| 69 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.69469484 |
| 70 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.69322491 |
| 71 | Retinol metabolism_Homo sapiens_hsa00830 | 0.65865729 |
| 72 | Morphine addiction_Homo sapiens_hsa05032 | 0.65843491 |
| 73 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.64840016 |
| 74 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.62641732 |
| 75 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.61157277 |
| 76 | Metabolic pathways_Homo sapiens_hsa01100 | 0.59881839 |
| 77 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.58996082 |
| 78 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.58491840 |
| 79 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.56780436 |
| 80 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.55383761 |
| 81 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.55265692 |
| 82 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.53635242 |
| 83 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.52871893 |
| 84 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.52484921 |
| 85 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.50625038 |
| 86 | Olfactory transduction_Homo sapiens_hsa04740 | 0.49018898 |
| 87 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.45428331 |
| 88 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.44952229 |
| 89 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.44875875 |
| 90 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.43771909 |
| 91 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.43002424 |
| 92 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.40922728 |
| 93 | GABAergic synapse_Homo sapiens_hsa04727 | 0.40871796 |
| 94 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.39005979 |
| 95 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.38980362 |
| 96 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.36251266 |
| 97 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.29517407 |
| 98 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.28777720 |
| 99 | Viral myocarditis_Homo sapiens_hsa05416 | 0.26318352 |
| 100 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.23780574 |

