

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | maturation of SSU-rRNA (GO:0030490) | 7.55554438 |
| 2 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 6.98595634 |
| 3 | base-excision repair, AP site formation (GO:0006285) | 6.74912820 |
| 4 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 6.48922031 |
| 5 | GDP-mannose metabolic process (GO:0019673) | 5.78151899 |
| 6 | pyrimidine nucleotide catabolic process (GO:0006244) | 5.70236285 |
| 7 | cellular response to ATP (GO:0071318) | 5.53037221 |
| 8 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.35548528 |
| 9 | dolichol-linked oligosaccharide biosynthetic process (GO:0006488) | 5.21790483 |
| 10 | chaperone-mediated protein transport (GO:0072321) | 5.12589902 |
| 11 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 4.85752517 |
| 12 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 4.55447072 |
| 13 | protein complex biogenesis (GO:0070271) | 4.49731959 |
| 14 | protein K63-linked deubiquitination (GO:0070536) | 4.45110672 |
| 15 | glomerular visceral epithelial cell development (GO:0072015) | 4.40414546 |
| 16 | ATP synthesis coupled proton transport (GO:0015986) | 4.32343297 |
| 17 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.32343297 |
| 18 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.22757125 |
| 19 | protein neddylation (GO:0045116) | 4.18181695 |
| 20 | axonemal dynein complex assembly (GO:0070286) | 4.17349151 |
| 21 | DNA deamination (GO:0045006) | 4.16510854 |
| 22 | regulation of mitochondrial translation (GO:0070129) | 4.15130041 |
| 23 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.10094643 |
| 24 | viral mRNA export from host cell nucleus (GO:0046784) | 4.08528847 |
| 25 | rRNA modification (GO:0000154) | 4.03977166 |
| 26 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.95816249 |
| 27 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.95816249 |
| 28 | NADH dehydrogenase complex assembly (GO:0010257) | 3.95816249 |
| 29 | maturation of 5.8S rRNA (GO:0000460) | 3.83340026 |
| 30 | glomerular epithelial cell development (GO:0072310) | 3.81414923 |
| 31 | proteasome assembly (GO:0043248) | 3.77181130 |
| 32 | purine-containing compound salvage (GO:0043101) | 3.74992346 |
| 33 | mannosylation (GO:0097502) | 3.72448789 |
| 34 | ribosomal large subunit biogenesis (GO:0042273) | 3.71279877 |
| 35 | nucleotide-excision repair, DNA damage removal (GO:0000718) | 3.67804173 |
| 36 | DNA excision (GO:0044349) | 3.67804173 |
| 37 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.61217356 |
| 38 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.60236070 |
| 39 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.60236070 |
| 40 | negative regulation of telomere maintenance (GO:0032205) | 3.56119852 |
| 41 | activated T cell proliferation (GO:0050798) | 3.54456549 |
| 42 | deoxyribonucleotide catabolic process (GO:0009264) | 3.52556693 |
| 43 | epithelial cilium movement (GO:0003351) | 3.51108227 |
| 44 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.49775603 |
| 45 | nucleotide-sugar metabolic process (GO:0009225) | 3.43105032 |
| 46 | rRNA methylation (GO:0031167) | 3.42716543 |
| 47 | cytochrome complex assembly (GO:0017004) | 3.41811200 |
| 48 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.40963002 |
| 49 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.40428248 |
| 50 | DNA replication checkpoint (GO:0000076) | 3.39283162 |
| 51 | GTP biosynthetic process (GO:0006183) | 3.39051015 |
| 52 | rRNA processing (GO:0006364) | 3.33333513 |
| 53 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.32090243 |
| 54 | ncRNA catabolic process (GO:0034661) | 3.28396957 |
| 55 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.27129853 |
| 56 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.23891017 |
| 57 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.23639493 |
| 58 | rRNA metabolic process (GO:0016072) | 3.23450187 |
| 59 | spliceosomal snRNP assembly (GO:0000387) | 3.20574643 |
| 60 | N-acetylglucosamine metabolic process (GO:0006044) | 3.20532479 |
| 61 | fucose catabolic process (GO:0019317) | 3.18899618 |
| 62 | L-fucose metabolic process (GO:0042354) | 3.18899618 |
| 63 | L-fucose catabolic process (GO:0042355) | 3.18899618 |
| 64 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.14658060 |
| 65 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.14658060 |
| 66 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.14658060 |
| 67 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.14368418 |
| 68 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.13702486 |
| 69 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.13702486 |
| 70 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.12226020 |
| 71 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.11680192 |
| 72 | nucleotide-sugar biosynthetic process (GO:0009226) | 3.09583659 |
| 73 | protein targeting to ER (GO:0045047) | 3.09531438 |
| 74 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.09196735 |
| 75 | termination of RNA polymerase III transcription (GO:0006386) | 3.09196735 |
| 76 | deoxyribose phosphate catabolic process (GO:0046386) | 3.07939137 |
| 77 | cotranslational protein targeting to membrane (GO:0006613) | 3.07231202 |
| 78 | viral transcription (GO:0019083) | 3.05883556 |
| 79 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.05450899 |
| 80 | negative regulation of ligase activity (GO:0051352) | 3.05450899 |
| 81 | 7-methylguanosine mRNA capping (GO:0006370) | 3.04588431 |
| 82 | cellular component biogenesis (GO:0044085) | 3.02558222 |
| 83 | electron transport chain (GO:0022900) | 3.01413093 |
| 84 | ribosomal small subunit biogenesis (GO:0042274) | 3.01176733 |
| 85 | ribosomal small subunit assembly (GO:0000028) | 3.01121036 |
| 86 | rRNA catabolic process (GO:0016075) | 2.99692966 |
| 87 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.98767236 |
| 88 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.98767236 |
| 89 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.98743490 |
| 90 | respiratory electron transport chain (GO:0022904) | 2.97497225 |
| 91 | 7-methylguanosine RNA capping (GO:0009452) | 2.96758213 |
| 92 | RNA capping (GO:0036260) | 2.96758213 |
| 93 | translation (GO:0006412) | 2.96188775 |
| 94 | protein localization to endoplasmic reticulum (GO:0070972) | 2.96181737 |
| 95 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.95406130 |
| 96 | protein K48-linked deubiquitination (GO:0071108) | 2.94021808 |
| 97 | translational termination (GO:0006415) | 2.92003711 |
| 98 | interferon-gamma production (GO:0032609) | 2.90019656 |
| 99 | behavioral response to nicotine (GO:0035095) | 2.89017910 |
| 100 | translational elongation (GO:0006414) | 2.88845551 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 5.70085934 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.40377735 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.21579127 |
| 4 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 3.95015135 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.53864761 |
| 6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.52534471 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.49770610 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.16259527 |
| 9 | VDR_22108803_ChIP-Seq_LS180_Human | 3.08392592 |
| 10 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.86277233 |
| 11 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.85325692 |
| 12 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.79029237 |
| 13 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.74702122 |
| 14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.65363742 |
| 15 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.60986912 |
| 16 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.60365040 |
| 17 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.25792744 |
| 18 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.22617733 |
| 19 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.14125527 |
| 20 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.13573269 |
| 21 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.13253139 |
| 22 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.05737563 |
| 23 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.97103147 |
| 24 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.96739452 |
| 25 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.85917297 |
| 26 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.84372642 |
| 27 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.81430854 |
| 28 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.76689584 |
| 29 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.72047923 |
| 30 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.69797894 |
| 31 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.68178879 |
| 32 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.66154466 |
| 33 | EWS_26573619_Chip-Seq_HEK293_Human | 1.65956861 |
| 34 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.62673441 |
| 35 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.54036000 |
| 36 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.51826634 |
| 37 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.51793864 |
| 38 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.50589095 |
| 39 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.48383017 |
| 40 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.44454608 |
| 41 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.43928350 |
| 42 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.42685976 |
| 43 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.39770472 |
| 44 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.35460885 |
| 45 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.34879116 |
| 46 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.33395851 |
| 47 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.32264846 |
| 48 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.30670101 |
| 49 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.30176499 |
| 50 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.29048319 |
| 51 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.27487019 |
| 52 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.27030558 |
| 53 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.26990346 |
| 54 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.24643842 |
| 55 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.22956017 |
| 56 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.22349538 |
| 57 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.21938137 |
| 58 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.21923834 |
| 59 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.20649467 |
| 60 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.20132354 |
| 61 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.19607645 |
| 62 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.17929947 |
| 63 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.17069321 |
| 64 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.16599948 |
| 65 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.15898603 |
| 66 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.15332547 |
| 67 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.12475525 |
| 68 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.11641788 |
| 69 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.08299321 |
| 70 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.06302356 |
| 71 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.05482580 |
| 72 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.03886739 |
| 73 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.02942710 |
| 74 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.01242769 |
| 75 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.99458810 |
| 76 | P300_19829295_ChIP-Seq_ESCs_Human | 0.99284272 |
| 77 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.96716355 |
| 78 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.96664244 |
| 79 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.95617114 |
| 80 | ERA_21632823_ChIP-Seq_H3396_Human | 0.95502914 |
| 81 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.94471388 |
| 82 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.93283017 |
| 83 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.91191765 |
| 84 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.90114715 |
| 85 | AR_20517297_ChIP-Seq_VCAP_Human | 0.90046286 |
| 86 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.89620463 |
| 87 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.87924221 |
| 88 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.87099111 |
| 89 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.86788619 |
| 90 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.85549136 |
| 91 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.84770040 |
| 92 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.84384666 |
| 93 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.84348699 |
| 94 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.84320197 |
| 95 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.82279951 |
| 96 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.80104190 |
| 97 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.78919399 |
| 98 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.77404416 |
| 99 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.76279956 |
| 100 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.75581025 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003693_abnormal_embryo_hatching | 3.75796131 |
| 2 | MP0005671_abnormal_response_to | 3.41898956 |
| 3 | MP0005084_abnormal_gallbladder_morpholo | 3.15267460 |
| 4 | MP0008058_abnormal_DNA_repair | 3.10364432 |
| 5 | MP0005408_hypopigmentation | 3.09110169 |
| 6 | MP0003646_muscle_fatigue | 3.05733867 |
| 7 | MP0002837_dystrophic_cardiac_calcinosis | 2.78160789 |
| 8 | MP0002102_abnormal_ear_morphology | 2.65543614 |
| 9 | MP0002938_white_spotting | 2.48422663 |
| 10 | MP0003786_premature_aging | 2.26275677 |
| 11 | MP0006292_abnormal_olfactory_placode | 2.23657741 |
| 12 | MP0004145_abnormal_muscle_electrophysio | 2.22856610 |
| 13 | MP0002736_abnormal_nociception_after | 2.15745249 |
| 14 | MP0004957_abnormal_blastocyst_morpholog | 2.09468412 |
| 15 | MP0000372_irregular_coat_pigmentation | 2.03965933 |
| 16 | MP0010030_abnormal_orbit_morphology | 1.99191974 |
| 17 | MP0003890_abnormal_embryonic-extraembry | 1.97200324 |
| 18 | MP0006072_abnormal_retinal_apoptosis | 1.96884968 |
| 19 | MP0000569_abnormal_digit_pigmentation | 1.92738313 |
| 20 | MP0004142_abnormal_muscle_tone | 1.88474417 |
| 21 | MP0003567_abnormal_fetal_cardiomyocyte | 1.83260555 |
| 22 | MP0008875_abnormal_xenobiotic_pharmacok | 1.80803673 |
| 23 | MP0004885_abnormal_endolymph | 1.77540729 |
| 24 | MP0003045_fibrosis | 1.72427008 |
| 25 | MP0003763_abnormal_thymus_physiology | 1.72274977 |
| 26 | MP0000566_synostosis | 1.68520503 |
| 27 | MP0002876_abnormal_thyroid_physiology | 1.67880618 |
| 28 | MP0002006_tumorigenesis | 1.62043909 |
| 29 | MP0001727_abnormal_embryo_implantation | 1.61037152 |
| 30 | MP0005167_abnormal_blood-brain_barrier | 1.58883965 |
| 31 | MP0003195_calcinosis | 1.57362107 |
| 32 | MP0001790_abnormal_immune_system | 1.49167925 |
| 33 | MP0005387_immune_system_phenotype | 1.49167925 |
| 34 | MP0008775_abnormal_heart_ventricle | 1.40694363 |
| 35 | MP0001968_abnormal_touch/_nociception | 1.40459366 |
| 36 | MP0008995_early_reproductive_senescence | 1.35692458 |
| 37 | MP0000049_abnormal_middle_ear | 1.35338362 |
| 38 | MP0008007_abnormal_cellular_replicative | 1.34743958 |
| 39 | MP0002166_altered_tumor_susceptibility | 1.33928586 |
| 40 | MP0010094_abnormal_chromosome_stability | 1.30668660 |
| 41 | MP0001905_abnormal_dopamine_level | 1.29072669 |
| 42 | MP0004147_increased_porphyrin_level | 1.27083808 |
| 43 | MP0001666_abnormal_nutrient_absorption | 1.25447476 |
| 44 | MP0008789_abnormal_olfactory_epithelium | 1.23375462 |
| 45 | MP0001485_abnormal_pinna_reflex | 1.23165710 |
| 46 | MP0001293_anophthalmia | 1.21602891 |
| 47 | MP0003011_delayed_dark_adaptation | 1.18920834 |
| 48 | MP0002090_abnormal_vision | 1.18898035 |
| 49 | MP0009785_altered_susceptibility_to | 1.17742763 |
| 50 | MP0003119_abnormal_digestive_system | 1.17203554 |
| 51 | MP0005253_abnormal_eye_physiology | 1.12706356 |
| 52 | MP0003111_abnormal_nucleus_morphology | 1.11125094 |
| 53 | MP0003950_abnormal_plasma_membrane | 1.08102838 |
| 54 | MP0001919_abnormal_reproductive_system | 1.07669946 |
| 55 | MP0005551_abnormal_eye_electrophysiolog | 1.05031496 |
| 56 | MP0003937_abnormal_limbs/digits/tail_de | 1.02474167 |
| 57 | MP0001873_stomach_inflammation | 0.98969162 |
| 58 | MP0005645_abnormal_hypothalamus_physiol | 0.98587690 |
| 59 | MP0003880_abnormal_central_pattern | 0.95824511 |
| 60 | MP0000747_muscle_weakness | 0.93606293 |
| 61 | MP0006036_abnormal_mitochondrial_physio | 0.92237526 |
| 62 | MP0004133_heterotaxia | 0.91817254 |
| 63 | MP0003943_abnormal_hepatobiliary_system | 0.90850732 |
| 64 | MP0008872_abnormal_physiological_respon | 0.90304415 |
| 65 | MP0002138_abnormal_hepatobiliary_system | 0.90025552 |
| 66 | MP0002210_abnormal_sex_determination | 0.88829807 |
| 67 | MP0005389_reproductive_system_phenotype | 0.87675823 |
| 68 | MP0005670_abnormal_white_adipose | 0.87207396 |
| 69 | MP0000613_abnormal_salivary_gland | 0.85719163 |
| 70 | MP0009379_abnormal_foot_pigmentation | 0.84859727 |
| 71 | MP0009053_abnormal_anal_canal | 0.84412041 |
| 72 | MP0002277_abnormal_respiratory_mucosa | 0.84381991 |
| 73 | MP0010368_abnormal_lymphatic_system | 0.84183030 |
| 74 | MP0003718_maternal_effect | 0.83739583 |
| 75 | MP0003938_abnormal_ear_development | 0.83302632 |
| 76 | MP0003866_abnormal_defecation | 0.82001660 |
| 77 | MP0002928_abnormal_bile_duct | 0.81579309 |
| 78 | MP0005195_abnormal_posterior_eye | 0.80583645 |
| 79 | MP0008877_abnormal_DNA_methylation | 0.80493887 |
| 80 | MP0000653_abnormal_sex_gland | 0.78324631 |
| 81 | MP0002653_abnormal_ependyma_morphology | 0.77983001 |
| 82 | MP0003077_abnormal_cell_cycle | 0.76354814 |
| 83 | MP0000470_abnormal_stomach_morphology | 0.73585031 |
| 84 | MP0001529_abnormal_vocalization | 0.72314292 |
| 85 | MP0002405_respiratory_system_inflammati | 0.71900893 |
| 86 | MP0002084_abnormal_developmental_patter | 0.71815964 |
| 87 | MP0002254_reproductive_system_inflammat | 0.69869605 |
| 88 | MP0006082_CNS_inflammation | 0.69092093 |
| 89 | MP0008057_abnormal_DNA_replication | 0.65951479 |
| 90 | MP0002160_abnormal_reproductive_system | 0.65250668 |
| 91 | MP0001145_abnormal_male_reproductive | 0.65231169 |
| 92 | MP0002067_abnormal_sensory_capabilities | 0.64938668 |
| 93 | MP0001119_abnormal_female_reproductive | 0.63252512 |
| 94 | MP0009697_abnormal_copulation | 0.62871312 |
| 95 | MP0004019_abnormal_vitamin_homeostasis | 0.62618223 |
| 96 | MP0002234_abnormal_pharynx_morphology | 0.59622110 |
| 97 | MP0005395_other_phenotype | 0.59337062 |
| 98 | MP0002420_abnormal_adaptive_immunity | 0.57633163 |
| 99 | MP0002752_abnormal_somatic_nervous | 0.57455212 |
| 100 | MP0000749_muscle_degeneration | 0.57197970 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Type I transferrin isoform profile (HP:0003642) | 5.39623044 |
| 2 | Abnormal protein glycosylation (HP:0012346) | 5.20026121 |
| 3 | Abnormal glycosylation (HP:0012345) | 5.20026121 |
| 4 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 5.20026121 |
| 5 | Abnormal protein N-linked glycosylation (HP:0012347) | 5.20026121 |
| 6 | Reduced antithrombin III activity (HP:0001976) | 4.82003218 |
| 7 | Abnormal respiratory epithelium morphology (HP:0012253) | 4.35802059 |
| 8 | Abnormal respiratory motile cilium morphology (HP:0005938) | 4.35802059 |
| 9 | Hypoproteinemia (HP:0003075) | 4.16963305 |
| 10 | 3-Methylglutaconic aciduria (HP:0003535) | 4.06478202 |
| 11 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.95982815 |
| 12 | Absent/shortened dynein arms (HP:0200106) | 3.95982815 |
| 13 | Testicular atrophy (HP:0000029) | 3.72817824 |
| 14 | Abnormality of the pons (HP:0007361) | 3.70622399 |
| 15 | Acute necrotizing encephalopathy (HP:0006965) | 3.69756681 |
| 16 | Hypoplasia of the pons (HP:0012110) | 3.68831412 |
| 17 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.51020466 |
| 18 | Abnormality of DNA repair (HP:0003254) | 3.43576797 |
| 19 | Aplastic anemia (HP:0001915) | 3.25182332 |
| 20 | Supernumerary spleens (HP:0009799) | 3.16008385 |
| 21 | Hepatocellular necrosis (HP:0001404) | 3.13835326 |
| 22 | Esophageal atresia (HP:0002032) | 3.13228015 |
| 23 | Mitochondrial inheritance (HP:0001427) | 3.11913664 |
| 24 | Myopathic facies (HP:0002058) | 3.10169494 |
| 25 | Methylmalonic acidemia (HP:0002912) | 2.96144667 |
| 26 | Acute encephalopathy (HP:0006846) | 2.94778070 |
| 27 | Progressive macrocephaly (HP:0004481) | 2.94575643 |
| 28 | Hepatic necrosis (HP:0002605) | 2.90689245 |
| 29 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.89752473 |
| 30 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.89752473 |
| 31 | Abnormal ciliary motility (HP:0012262) | 2.87169302 |
| 32 | Prolonged QT interval (HP:0001657) | 2.66778994 |
| 33 | Dyschromatopsia (HP:0007641) | 2.64639684 |
| 34 | Duplicated collecting system (HP:0000081) | 2.64574440 |
| 35 | Absent speech (HP:0001344) | 2.61578232 |
| 36 | Increased CSF lactate (HP:0002490) | 2.61344674 |
| 37 | Autoimmune thrombocytopenia (HP:0001973) | 2.60131082 |
| 38 | Molar tooth sign on MRI (HP:0002419) | 2.56839543 |
| 39 | Abnormality of midbrain morphology (HP:0002418) | 2.56839543 |
| 40 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.55086348 |
| 41 | Abnormality of the renal collecting system (HP:0004742) | 2.50766144 |
| 42 | Methylmalonic aciduria (HP:0012120) | 2.47008561 |
| 43 | Absent phalangeal crease (HP:0006109) | 2.46493457 |
| 44 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.46266847 |
| 45 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.42823335 |
| 46 | Decreased subcutaneous fat (HP:0001002) | 2.41210217 |
| 47 | Increased hepatocellular lipid droplets (HP:0006565) | 2.38277468 |
| 48 | Visual hallucinations (HP:0002367) | 2.37070919 |
| 49 | Infertility (HP:0000789) | 2.33898516 |
| 50 | Autoimmune hemolytic anemia (HP:0001890) | 2.33018363 |
| 51 | Bronchiectasis (HP:0002110) | 2.32000179 |
| 52 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.30246200 |
| 53 | Reticulocytopenia (HP:0001896) | 2.22120500 |
| 54 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.20227289 |
| 55 | Exercise intolerance (HP:0003546) | 2.20029259 |
| 56 | Pancytopenia (HP:0001876) | 2.19506485 |
| 57 | Cerebral edema (HP:0002181) | 2.17058777 |
| 58 | CNS demyelination (HP:0007305) | 2.15853533 |
| 59 | Lipid accumulation in hepatocytes (HP:0006561) | 2.13398588 |
| 60 | Asplenia (HP:0001746) | 2.10417078 |
| 61 | Poor head control (HP:0002421) | 2.10341238 |
| 62 | Abnormal finger flexion creases (HP:0006143) | 2.07762791 |
| 63 | Adrenal hypoplasia (HP:0000835) | 2.07690297 |
| 64 | Absent thumb (HP:0009777) | 2.06291756 |
| 65 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.05667669 |
| 66 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 2.05164511 |
| 67 | Generalized aminoaciduria (HP:0002909) | 2.03673296 |
| 68 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 1.96298071 |
| 69 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.95263391 |
| 70 | Increased intramyocellular lipid droplets (HP:0012240) | 1.94510546 |
| 71 | Nephronophthisis (HP:0000090) | 1.94390851 |
| 72 | Exertional dyspnea (HP:0002875) | 1.93302872 |
| 73 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.92958186 |
| 74 | Large for gestational age (HP:0001520) | 1.90137667 |
| 75 | Central scotoma (HP:0000603) | 1.89228337 |
| 76 | Congenital stationary night blindness (HP:0007642) | 1.87520759 |
| 77 | Gastrointestinal atresia (HP:0002589) | 1.85901977 |
| 78 | Gout (HP:0001997) | 1.83748288 |
| 79 | Humeroradial synostosis (HP:0003041) | 1.83094990 |
| 80 | Synostosis involving the elbow (HP:0003938) | 1.83094990 |
| 81 | Abnormality of purine metabolism (HP:0004352) | 1.81721629 |
| 82 | Broad distal phalanx of finger (HP:0009836) | 1.81633106 |
| 83 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.81119954 |
| 84 | Nasal polyposis (HP:0100582) | 1.78237536 |
| 85 | Abnormality of the middle phalanges of the toes (HP:0010183) | 1.77467082 |
| 86 | Respiratory failure (HP:0002878) | 1.76918805 |
| 87 | Parakeratosis (HP:0001036) | 1.75524308 |
| 88 | Hypochromic microcytic anemia (HP:0004840) | 1.75210996 |
| 89 | Abnormality of the renal cortex (HP:0011035) | 1.74366312 |
| 90 | Macrocytic anemia (HP:0001972) | 1.73724006 |
| 91 | Abnormality of vitamin B metabolism (HP:0004340) | 1.72290714 |
| 92 | Increased serum lactate (HP:0002151) | 1.72100768 |
| 93 | Cerebral hypomyelination (HP:0006808) | 1.71644593 |
| 94 | Lactic acidosis (HP:0003128) | 1.70913681 |
| 95 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.69822547 |
| 96 | Rhinitis (HP:0012384) | 1.68980613 |
| 97 | Milia (HP:0001056) | 1.68364242 |
| 98 | Clubbing of toes (HP:0100760) | 1.66062010 |
| 99 | Abnormality of the labia minora (HP:0012880) | 1.65270417 |
| 100 | Abnormality of subcutaneous fat tissue (HP:0001001) | 1.64792162 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TIE1 | 5.30345124 |
| 2 | CAMKK2 | 3.17675096 |
| 3 | BCKDK | 2.88502064 |
| 4 | BUB1 | 2.80325604 |
| 5 | GRK1 | 2.72679126 |
| 6 | NEK1 | 2.71335164 |
| 7 | TXK | 2.67050031 |
| 8 | NEK9 | 2.52043289 |
| 9 | VRK2 | 2.41369810 |
| 10 | MAP3K12 | 2.36508024 |
| 11 | STK16 | 2.15475806 |
| 12 | TSSK6 | 2.06377973 |
| 13 | IKBKE | 2.01064748 |
| 14 | TLK1 | 1.97114976 |
| 15 | WNK4 | 1.83237015 |
| 16 | EIF2AK1 | 1.74264000 |
| 17 | STK39 | 1.69953963 |
| 18 | MST4 | 1.68910970 |
| 19 | KDR | 1.66897057 |
| 20 | TESK2 | 1.66764950 |
| 21 | INSRR | 1.62031185 |
| 22 | PLK4 | 1.53096401 |
| 23 | WNK3 | 1.52356381 |
| 24 | BRSK2 | 1.40509049 |
| 25 | TAF1 | 1.32124373 |
| 26 | ZAK | 1.31224654 |
| 27 | OXSR1 | 1.25873060 |
| 28 | DAPK2 | 1.21995280 |
| 29 | JAK3 | 1.21007241 |
| 30 | ADRBK2 | 1.18620826 |
| 31 | NUAK1 | 1.11907016 |
| 32 | LIMK1 | 1.11859678 |
| 33 | TAOK3 | 1.11631606 |
| 34 | PNCK | 1.08359868 |
| 35 | PIK3CG | 1.06084093 |
| 36 | CHEK2 | 1.05908328 |
| 37 | IKBKB | 1.05695178 |
| 38 | DAPK1 | 1.05284915 |
| 39 | EIF2AK3 | 1.04266158 |
| 40 | NME1 | 1.03261697 |
| 41 | CCNB1 | 0.95161512 |
| 42 | WEE1 | 0.94487904 |
| 43 | PHKG1 | 0.93182658 |
| 44 | PHKG2 | 0.93182658 |
| 45 | MAP4K2 | 0.91683531 |
| 46 | BRSK1 | 0.91064985 |
| 47 | PLK3 | 0.90329439 |
| 48 | DYRK2 | 0.89588651 |
| 49 | MAP4K1 | 0.85782230 |
| 50 | NME2 | 0.82412617 |
| 51 | CAMK2D | 0.81597098 |
| 52 | AURKA | 0.78257344 |
| 53 | CDK7 | 0.77794431 |
| 54 | MAP2K7 | 0.75210904 |
| 55 | OBSCN | 0.72517221 |
| 56 | ATR | 0.71410553 |
| 57 | CDC7 | 0.70422318 |
| 58 | CAMKK1 | 0.68737904 |
| 59 | PLK1 | 0.68268570 |
| 60 | WNK1 | 0.67151541 |
| 61 | CAMK2G | 0.66001054 |
| 62 | MAP3K14 | 0.65620206 |
| 63 | TEC | 0.62632994 |
| 64 | CAMK1D | 0.62559696 |
| 65 | EPHA4 | 0.60476601 |
| 66 | VRK1 | 0.57871702 |
| 67 | CSNK1A1 | 0.57654045 |
| 68 | SRPK1 | 0.55787133 |
| 69 | PINK1 | 0.55614489 |
| 70 | ITK | 0.54989975 |
| 71 | MAPK15 | 0.54491939 |
| 72 | IRAK1 | 0.53069556 |
| 73 | MAP3K11 | 0.52977280 |
| 74 | TRIM28 | 0.51394160 |
| 75 | FRK | 0.50363257 |
| 76 | CSNK1G2 | 0.49698972 |
| 77 | CSNK2A2 | 0.49171594 |
| 78 | CSNK2A1 | 0.48394866 |
| 79 | EPHB2 | 0.47406570 |
| 80 | MYLK | 0.47266317 |
| 81 | LRRK2 | 0.46991580 |
| 82 | CSNK1G3 | 0.46516422 |
| 83 | ABL2 | 0.46456164 |
| 84 | GRK5 | 0.46409803 |
| 85 | CSNK1A1L | 0.45752799 |
| 86 | ATM | 0.45177529 |
| 87 | FES | 0.45148754 |
| 88 | TESK1 | 0.44808093 |
| 89 | MAPK10 | 0.44209762 |
| 90 | ALK | 0.42412643 |
| 91 | MKNK1 | 0.41341594 |
| 92 | ILK | 0.40761733 |
| 93 | MARK1 | 0.37355056 |
| 94 | AURKB | 0.37039321 |
| 95 | STK4 | 0.35287481 |
| 96 | PASK | 0.35082251 |
| 97 | GSK3A | 0.34971800 |
| 98 | LMTK2 | 0.34846200 |
| 99 | PRKCE | 0.34231920 |
| 100 | PRKDC | 0.33546034 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.11724466 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 3.68703928 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.55303737 |
| 4 | Protein export_Homo sapiens_hsa03060 | 3.05982499 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 2.85224714 |
| 6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.76497985 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.51443363 |
| 8 | Homologous recombination_Homo sapiens_hsa03440 | 2.43102853 |
| 9 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.31647670 |
| 10 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 2.31468689 |
| 11 | Basal transcription factors_Homo sapiens_hsa03022 | 2.29206212 |
| 12 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.22085555 |
| 13 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 2.11920282 |
| 14 | Huntingtons disease_Homo sapiens_hsa05016 | 2.05748789 |
| 15 | Spliceosome_Homo sapiens_hsa03040 | 1.98012168 |
| 16 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.95082656 |
| 17 | Alzheimers disease_Homo sapiens_hsa05010 | 1.89086527 |
| 18 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.79925425 |
| 19 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.76937040 |
| 20 | DNA replication_Homo sapiens_hsa03030 | 1.74160418 |
| 21 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.71897063 |
| 22 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.68161834 |
| 23 | RNA degradation_Homo sapiens_hsa03018 | 1.61604906 |
| 24 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.60272357 |
| 25 | RNA transport_Homo sapiens_hsa03013 | 1.49971122 |
| 26 | Mismatch repair_Homo sapiens_hsa03430 | 1.43673966 |
| 27 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.41916381 |
| 28 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.35304084 |
| 29 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.33031585 |
| 30 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.28880267 |
| 31 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.28408589 |
| 32 | Phototransduction_Homo sapiens_hsa04744 | 1.21919052 |
| 33 | Purine metabolism_Homo sapiens_hsa00230 | 1.21357847 |
| 34 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.16827082 |
| 35 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.14633480 |
| 36 | Base excision repair_Homo sapiens_hsa03410 | 1.11722036 |
| 37 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.11023949 |
| 38 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.02652802 |
| 39 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.98211929 |
| 40 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.97659394 |
| 41 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.97398266 |
| 42 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.94293996 |
| 43 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.92641709 |
| 44 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.91040696 |
| 45 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.87554530 |
| 46 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.86050446 |
| 47 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.81352628 |
| 48 | Histidine metabolism_Homo sapiens_hsa00340 | 0.80643367 |
| 49 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.79286296 |
| 50 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.75524643 |
| 51 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.75372638 |
| 52 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.74751514 |
| 53 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.73237889 |
| 54 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.72485699 |
| 55 | Metabolic pathways_Homo sapiens_hsa01100 | 0.70078833 |
| 56 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.68894753 |
| 57 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.63920856 |
| 58 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.63299381 |
| 59 | Olfactory transduction_Homo sapiens_hsa04740 | 0.63015356 |
| 60 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.62063161 |
| 61 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.61491576 |
| 62 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.58531281 |
| 63 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.54135131 |
| 64 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.50748762 |
| 65 | Nicotine addiction_Homo sapiens_hsa05033 | 0.47410908 |
| 66 | ABC transporters_Homo sapiens_hsa02010 | 0.45142999 |
| 67 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.45098040 |
| 68 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.44694497 |
| 69 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.43527002 |
| 70 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.41735068 |
| 71 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.41519054 |
| 72 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.41026171 |
| 73 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.39543643 |
| 74 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.36926118 |
| 75 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.35969461 |
| 76 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.32388073 |
| 77 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.32258907 |
| 78 | Allograft rejection_Homo sapiens_hsa05330 | 0.31680182 |
| 79 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.31286904 |
| 80 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.31127537 |
| 81 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.30657988 |
| 82 | Tight junction_Homo sapiens_hsa04530 | 0.30477427 |
| 83 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.30241700 |
| 84 | Retinol metabolism_Homo sapiens_hsa00830 | 0.28772495 |
| 85 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.28020342 |
| 86 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.27854936 |
| 87 | Mineral absorption_Homo sapiens_hsa04978 | 0.27670527 |
| 88 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.27327163 |
| 89 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.26987552 |
| 90 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.26433523 |
| 91 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.26112486 |
| 92 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.26103276 |
| 93 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.24315654 |
| 94 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.23037493 |
| 95 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.22981591 |
| 96 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.22024018 |
| 97 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.21034901 |
| 98 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.20425213 |
| 99 | Taste transduction_Homo sapiens_hsa04742 | 0.19743137 |
| 100 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.18674177 |

