

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 6.46511546 |
| 2 | proteasome assembly (GO:0043248) | 5.38570473 |
| 3 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.35890628 |
| 4 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.19131901 |
| 5 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.82442769 |
| 6 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.56280009 |
| 7 | cytidine metabolic process (GO:0046087) | 4.50314484 |
| 8 | cytidine catabolic process (GO:0006216) | 4.50314484 |
| 9 | cytidine deamination (GO:0009972) | 4.50314484 |
| 10 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.43993523 |
| 11 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 4.41191921 |
| 12 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.27539973 |
| 13 | ATP synthesis coupled proton transport (GO:0015986) | 4.27539973 |
| 14 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.24642647 |
| 15 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 4.20599827 |
| 16 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 4.07891996 |
| 17 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 4.06459783 |
| 18 | rRNA modification (GO:0000154) | 4.05723288 |
| 19 | negative regulation of ligase activity (GO:0051352) | 4.03470139 |
| 20 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 4.03470139 |
| 21 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.97758445 |
| 22 | protein neddylation (GO:0045116) | 3.97510327 |
| 23 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.97150229 |
| 24 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.97150229 |
| 25 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.97150229 |
| 26 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.95829855 |
| 27 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.92691294 |
| 28 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.88134782 |
| 29 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.88134782 |
| 30 | rRNA methylation (GO:0031167) | 3.84001248 |
| 31 | regulation of immunoglobulin secretion (GO:0051023) | 3.81976425 |
| 32 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.78327472 |
| 33 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.78327472 |
| 34 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.75197552 |
| 35 | termination of RNA polymerase III transcription (GO:0006386) | 3.75197552 |
| 36 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.74935716 |
| 37 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.72865551 |
| 38 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.72313597 |
| 39 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.68117359 |
| 40 | ribosome assembly (GO:0042255) | 3.61313551 |
| 41 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.61026720 |
| 42 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.54138870 |
| 43 | regulation of podosome assembly (GO:0071801) | 3.52670683 |
| 44 | platelet dense granule organization (GO:0060155) | 3.48908551 |
| 45 | ribosomal small subunit assembly (GO:0000028) | 3.45476131 |
| 46 | cullin deneddylation (GO:0010388) | 3.43828627 |
| 47 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.42605725 |
| 48 | DNA double-strand break processing (GO:0000729) | 3.36444598 |
| 49 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.36236915 |
| 50 | NADH dehydrogenase complex assembly (GO:0010257) | 3.36236915 |
| 51 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.36236915 |
| 52 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.34770158 |
| 53 | positive regulation of isotype switching (GO:0045830) | 3.34522674 |
| 54 | intracellular protein transmembrane import (GO:0044743) | 3.34243272 |
| 55 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.34082638 |
| 56 | respiratory chain complex IV assembly (GO:0008535) | 3.30761002 |
| 57 | positive regulation of ligase activity (GO:0051351) | 3.29544262 |
| 58 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.24078171 |
| 59 | protein complex biogenesis (GO:0070271) | 3.22501713 |
| 60 | chaperone-mediated protein transport (GO:0072321) | 3.18882828 |
| 61 | regulation of regulatory T cell differentiation (GO:0045589) | 3.13553704 |
| 62 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.10666536 |
| 63 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.09963648 |
| 64 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.09963648 |
| 65 | signal peptide processing (GO:0006465) | 3.09184835 |
| 66 | positive regulation of DNA recombination (GO:0045911) | 3.03653523 |
| 67 | protein deneddylation (GO:0000338) | 3.02405792 |
| 68 | regulation of cellular amine metabolic process (GO:0033238) | 3.01915011 |
| 69 | base-excision repair, AP site formation (GO:0006285) | 3.01581766 |
| 70 | negative regulation of protein ubiquitination (GO:0031397) | 3.00368238 |
| 71 | positive regulation of cell cycle arrest (GO:0071158) | 3.00217499 |
| 72 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.98329969 |
| 73 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.97275480 |
| 74 | respiratory electron transport chain (GO:0022904) | 2.93186321 |
| 75 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.93146218 |
| 76 | electron transport chain (GO:0022900) | 2.89558147 |
| 77 | spliceosomal snRNP assembly (GO:0000387) | 2.88323681 |
| 78 | peptidyl-histidine modification (GO:0018202) | 2.85718367 |
| 79 | regulation of chronic inflammatory response (GO:0002676) | 2.85323686 |
| 80 | regulation of ligase activity (GO:0051340) | 2.84349063 |
| 81 | histone H2A acetylation (GO:0043968) | 2.81352800 |
| 82 | pseudouridine synthesis (GO:0001522) | 2.77664865 |
| 83 | negative regulation of protein modification by small protein conjugation or removal (GO:1903321) | 2.75672591 |
| 84 | L-methionine salvage (GO:0071267) | 2.74886371 |
| 85 | L-methionine biosynthetic process (GO:0071265) | 2.74886371 |
| 86 | amino acid salvage (GO:0043102) | 2.74886371 |
| 87 | DNA damage response, detection of DNA damage (GO:0042769) | 2.71492731 |
| 88 | rRNA processing (GO:0006364) | 2.69121049 |
| 89 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.65333855 |
| 90 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.65153448 |
| 91 | cytochrome complex assembly (GO:0017004) | 2.65149202 |
| 92 | protein targeting to mitochondrion (GO:0006626) | 2.64950000 |
| 93 | rRNA metabolic process (GO:0016072) | 2.63397953 |
| 94 | amino acid activation (GO:0043038) | 2.61766801 |
| 95 | tRNA aminoacylation (GO:0043039) | 2.61766801 |
| 96 | termination of RNA polymerase I transcription (GO:0006363) | 2.59154621 |
| 97 | regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139) | 2.58639518 |
| 98 | positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141) | 2.58639518 |
| 99 | protein localization to mitochondrion (GO:0070585) | 2.53789973 |
| 100 | positive regulation of immunoglobulin production (GO:0002639) | 2.52238071 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.00377273 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.30836097 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.98960559 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.57536482 |
| 5 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.13124854 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.01130367 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.97919187 |
| 8 | VDR_22108803_ChIP-Seq_LS180_Human | 2.82911447 |
| 9 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.73878747 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.71144194 |
| 11 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.67115789 |
| 12 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.63828076 |
| 13 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.55444186 |
| 14 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.55097572 |
| 15 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.54664579 |
| 16 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.53982536 |
| 17 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.49470224 |
| 18 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.43060335 |
| 19 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.36626692 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.29760086 |
| 21 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.23444800 |
| 22 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.12310975 |
| 23 | EWS_26573619_Chip-Seq_HEK293_Human | 2.10763905 |
| 24 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.09945963 |
| 25 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.00772531 |
| 26 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.92328766 |
| 27 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.91259092 |
| 28 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.89291196 |
| 29 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.84705990 |
| 30 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.82052592 |
| 31 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.80755494 |
| 32 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.71305529 |
| 33 | FUS_26573619_Chip-Seq_HEK293_Human | 1.68069090 |
| 34 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.66258524 |
| 35 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.63785024 |
| 36 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.59904631 |
| 37 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.56510534 |
| 38 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.55373157 |
| 39 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.51454622 |
| 40 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.50208151 |
| 41 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.48018336 |
| 42 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.46668211 |
| 43 | P300_19829295_ChIP-Seq_ESCs_Human | 1.44209109 |
| 44 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.38119160 |
| 45 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.37656390 |
| 46 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.26758064 |
| 47 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.26758064 |
| 48 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.26687919 |
| 49 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.26420431 |
| 50 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.26183912 |
| 51 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.23871507 |
| 52 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.23799977 |
| 53 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.22720018 |
| 54 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.19465332 |
| 55 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.17888557 |
| 56 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.17632004 |
| 57 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.17579771 |
| 58 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.17531641 |
| 59 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.17204158 |
| 60 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.16547193 |
| 61 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.15782325 |
| 62 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.15687453 |
| 63 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.15674647 |
| 64 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.14729823 |
| 65 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.14039243 |
| 66 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.12700537 |
| 67 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.12158613 |
| 68 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.10906167 |
| 69 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.10558503 |
| 70 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.08622911 |
| 71 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.07109728 |
| 72 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.06270889 |
| 73 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.05763077 |
| 74 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.03004730 |
| 75 | GATA3_26560356_Chip-Seq_TH2_Human | 1.02949410 |
| 76 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.02290188 |
| 77 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.99968460 |
| 78 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.99822522 |
| 79 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.99181552 |
| 80 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.99181552 |
| 81 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.97600396 |
| 82 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.96953100 |
| 83 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.96953100 |
| 84 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.96180578 |
| 85 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.95980912 |
| 86 | AR_20517297_ChIP-Seq_VCAP_Human | 0.95296643 |
| 87 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.94589096 |
| 88 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.94010404 |
| 89 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.92939939 |
| 90 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.92341018 |
| 91 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.92195451 |
| 92 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.89939392 |
| 93 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.89453068 |
| 94 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.87602238 |
| 95 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.86257847 |
| 96 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.85438916 |
| 97 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.85215233 |
| 98 | NCOR_22424771_ChIP-Seq_293T_Human | 0.84707071 |
| 99 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.84350170 |
| 100 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.83994442 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003806_abnormal_nucleotide_metabolis | 4.52098762 |
| 2 | MP0001835_abnormal_antigen_presentation | 4.19722503 |
| 3 | MP0005671_abnormal_response_to | 3.38508218 |
| 4 | MP0001873_stomach_inflammation | 3.33405174 |
| 5 | MP0005084_abnormal_gallbladder_morpholo | 2.72941821 |
| 6 | MP0006292_abnormal_olfactory_placode | 2.54034577 |
| 7 | MP0002102_abnormal_ear_morphology | 2.44869688 |
| 8 | MP0008058_abnormal_DNA_repair | 2.26246878 |
| 9 | MP0006072_abnormal_retinal_apoptosis | 2.19187406 |
| 10 | MP0003786_premature_aging | 2.17050177 |
| 11 | MP0009785_altered_susceptibility_to | 2.12285593 |
| 12 | MP0004957_abnormal_blastocyst_morpholog | 2.03678658 |
| 13 | MP0003195_calcinosis | 2.01642234 |
| 14 | MP0004145_abnormal_muscle_electrophysio | 1.92673436 |
| 15 | MP0010094_abnormal_chromosome_stability | 1.87779098 |
| 16 | MP0003567_abnormal_fetal_cardiomyocyte | 1.87012571 |
| 17 | MP0003693_abnormal_embryo_hatching | 1.84060048 |
| 18 | MP0006036_abnormal_mitochondrial_physio | 1.74966788 |
| 19 | MP0005551_abnormal_eye_electrophysiolog | 1.73906030 |
| 20 | MP0002148_abnormal_hypersensitivity_rea | 1.71699898 |
| 21 | MP0008872_abnormal_physiological_respon | 1.71143040 |
| 22 | MP0002234_abnormal_pharynx_morphology | 1.69568026 |
| 23 | MP0008875_abnormal_xenobiotic_pharmacok | 1.68475267 |
| 24 | MP0002277_abnormal_respiratory_mucosa | 1.65075526 |
| 25 | MP0005377_hearing/vestibular/ear_phenot | 1.64138329 |
| 26 | MP0003878_abnormal_ear_physiology | 1.64138329 |
| 27 | MP0003718_maternal_effect | 1.62077787 |
| 28 | MP0001293_anophthalmia | 1.61885865 |
| 29 | MP0006035_abnormal_mitochondrial_morpho | 1.60071394 |
| 30 | MP0002138_abnormal_hepatobiliary_system | 1.58646556 |
| 31 | MP0009697_abnormal_copulation | 1.57066644 |
| 32 | MP0004142_abnormal_muscle_tone | 1.57020566 |
| 33 | MP0002736_abnormal_nociception_after | 1.54957928 |
| 34 | MP0005310_abnormal_salivary_gland | 1.54945198 |
| 35 | MP0003283_abnormal_digestive_organ | 1.49821168 |
| 36 | MP0003186_abnormal_redox_activity | 1.47761227 |
| 37 | MP0005387_immune_system_phenotype | 1.46910661 |
| 38 | MP0001790_abnormal_immune_system | 1.46910661 |
| 39 | MP0004147_increased_porphyrin_level | 1.38929539 |
| 40 | MP0001485_abnormal_pinna_reflex | 1.38336277 |
| 41 | MP0005451_abnormal_body_composition | 1.34144063 |
| 42 | MP0001853_heart_inflammation | 1.32321244 |
| 43 | MP0002166_altered_tumor_susceptibility | 1.30105114 |
| 44 | MP0002653_abnormal_ependyma_morphology | 1.29345246 |
| 45 | MP0003880_abnormal_central_pattern | 1.27130826 |
| 46 | MP0000631_abnormal_neuroendocrine_gland | 1.23692384 |
| 47 | MP0004742_abnormal_vestibular_system | 1.23197771 |
| 48 | MP0002006_tumorigenesis | 1.21481557 |
| 49 | MP0008877_abnormal_DNA_methylation | 1.17879378 |
| 50 | MP0008995_early_reproductive_senescence | 1.14104292 |
| 51 | MP0005253_abnormal_eye_physiology | 1.09741021 |
| 52 | MP0001968_abnormal_touch/_nociception | 1.07861932 |
| 53 | MP0010386_abnormal_urinary_bladder | 1.07563015 |
| 54 | MP0008789_abnormal_olfactory_epithelium | 1.04032369 |
| 55 | MP0001800_abnormal_humoral_immune | 1.02734656 |
| 56 | MP0002938_white_spotting | 1.01628798 |
| 57 | MP0001663_abnormal_digestive_system | 0.99731797 |
| 58 | MP0003137_abnormal_impulse_conducting | 0.97553160 |
| 59 | MP0002405_respiratory_system_inflammati | 0.96142631 |
| 60 | MP0003136_yellow_coat_color | 0.96039138 |
| 61 | MP0000383_abnormal_hair_follicle | 0.95137779 |
| 62 | MP0009765_abnormal_xenobiotic_induced | 0.91806566 |
| 63 | MP0005645_abnormal_hypothalamus_physiol | 0.91316675 |
| 64 | MP0000427_abnormal_hair_cycle | 0.89272318 |
| 65 | MP0005646_abnormal_pituitary_gland | 0.88814937 |
| 66 | MP0001905_abnormal_dopamine_level | 0.88164118 |
| 67 | MP0005000_abnormal_immune_tolerance | 0.88127862 |
| 68 | MP0003866_abnormal_defecation | 0.87145963 |
| 69 | MP0004215_abnormal_myocardial_fiber | 0.86322478 |
| 70 | MP0003111_abnormal_nucleus_morphology | 0.85634200 |
| 71 | MP0005395_other_phenotype | 0.85005736 |
| 72 | MP0000685_abnormal_immune_system | 0.84120569 |
| 73 | MP0002733_abnormal_thermal_nociception | 0.83996442 |
| 74 | MP0009333_abnormal_splenocyte_physiolog | 0.79944586 |
| 75 | MP0002751_abnormal_autonomic_nervous | 0.79783851 |
| 76 | MP0002282_abnormal_trachea_morphology | 0.79482227 |
| 77 | MP0006276_abnormal_autonomic_nervous | 0.75232221 |
| 78 | MP0001764_abnormal_homeostasis | 0.74365408 |
| 79 | MP0009745_abnormal_behavioral_response | 0.72099423 |
| 80 | MP0003119_abnormal_digestive_system | 0.71684441 |
| 81 | MP0006082_CNS_inflammation | 0.71644450 |
| 82 | MP0005195_abnormal_posterior_eye | 0.70453766 |
| 83 | MP0000358_abnormal_cell_content/ | 0.68776821 |
| 84 | MP0005381_digestive/alimentary_phenotyp | 0.68644766 |
| 85 | MP0001929_abnormal_gametogenesis | 0.68313039 |
| 86 | MP0002420_abnormal_adaptive_immunity | 0.68037121 |
| 87 | MP0008007_abnormal_cellular_replicative | 0.67699332 |
| 88 | MP0001819_abnormal_immune_cell | 0.67597046 |
| 89 | MP0002272_abnormal_nervous_system | 0.66962546 |
| 90 | MP0002723_abnormal_immune_serum | 0.66413361 |
| 91 | MP0010307_abnormal_tumor_latency | 0.66286117 |
| 92 | MP0010155_abnormal_intestine_physiology | 0.66123188 |
| 93 | MP0002210_abnormal_sex_determination | 0.64397297 |
| 94 | MP0000467_abnormal_esophagus_morphology | 0.64291711 |
| 95 | MP0003938_abnormal_ear_development | 0.64119236 |
| 96 | MP0001286_abnormal_eye_development | 0.63165609 |
| 97 | MP0003937_abnormal_limbs/digits/tail_de | 0.63042055 |
| 98 | MP0001986_abnormal_taste_sensitivity | 0.62571291 |
| 99 | MP0004133_heterotaxia | 0.62556930 |
| 100 | MP0001970_abnormal_pain_threshold | 0.62308200 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aplastic anemia (HP:0001915) | 4.66802228 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 3.93955096 |
| 3 | Increased hepatocellular lipid droplets (HP:0006565) | 3.77333349 |
| 4 | Mitochondrial inheritance (HP:0001427) | 3.63910406 |
| 5 | Abnormality of midbrain morphology (HP:0002418) | 3.58149398 |
| 6 | Molar tooth sign on MRI (HP:0002419) | 3.58149398 |
| 7 | Stomatitis (HP:0010280) | 3.57291834 |
| 8 | Acute encephalopathy (HP:0006846) | 3.53888816 |
| 9 | Increased CSF lactate (HP:0002490) | 3.44568245 |
| 10 | Colon cancer (HP:0003003) | 3.41228162 |
| 11 | Hepatocellular necrosis (HP:0001404) | 3.31364290 |
| 12 | Pancreatic cysts (HP:0001737) | 3.27468942 |
| 13 | Lipid accumulation in hepatocytes (HP:0006561) | 3.26607497 |
| 14 | 3-Methylglutaconic aciduria (HP:0003535) | 3.23861700 |
| 15 | True hermaphroditism (HP:0010459) | 3.21532212 |
| 16 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.21293251 |
| 17 | Increased IgM level (HP:0003496) | 3.19951478 |
| 18 | IgG deficiency (HP:0004315) | 3.17230797 |
| 19 | Progressive macrocephaly (HP:0004481) | 3.14401254 |
| 20 | Abnormality of alanine metabolism (HP:0010916) | 3.14076068 |
| 21 | Hyperalaninemia (HP:0003348) | 3.14076068 |
| 22 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.14076068 |
| 23 | Methylmalonic acidemia (HP:0002912) | 2.98927831 |
| 24 | Hepatic necrosis (HP:0002605) | 2.95400764 |
| 25 | Pancreatic fibrosis (HP:0100732) | 2.88638838 |
| 26 | Pancytopenia (HP:0001876) | 2.81540995 |
| 27 | Increased serum lactate (HP:0002151) | 2.79684077 |
| 28 | Optic disc pallor (HP:0000543) | 2.78786789 |
| 29 | Renal Fanconi syndrome (HP:0001994) | 2.75549053 |
| 30 | Cerebral edema (HP:0002181) | 2.70663195 |
| 31 | Microvesicular hepatic steatosis (HP:0001414) | 2.69001243 |
| 32 | Abnormality of the labia minora (HP:0012880) | 2.58979187 |
| 33 | Nephronophthisis (HP:0000090) | 2.53985993 |
| 34 | Hypoproteinemia (HP:0003075) | 2.52623334 |
| 35 | Type I transferrin isoform profile (HP:0003642) | 2.52110596 |
| 36 | Abnormality of serum amino acid levels (HP:0003112) | 2.49218439 |
| 37 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.49142581 |
| 38 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.42956719 |
| 39 | Abolished electroretinogram (ERG) (HP:0000550) | 2.42835491 |
| 40 | Exertional dyspnea (HP:0002875) | 2.40934095 |
| 41 | Increased serum pyruvate (HP:0003542) | 2.37230847 |
| 42 | Lactic acidosis (HP:0003128) | 2.33788256 |
| 43 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.31801430 |
| 44 | Leukodystrophy (HP:0002415) | 2.24255470 |
| 45 | Lethargy (HP:0001254) | 2.22824399 |
| 46 | Methylmalonic aciduria (HP:0012120) | 2.22004970 |
| 47 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.19108458 |
| 48 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.17270083 |
| 49 | Congenital, generalized hypertrichosis (HP:0004540) | 2.17007420 |
| 50 | Attenuation of retinal blood vessels (HP:0007843) | 2.10404052 |
| 51 | Abnormality of methionine metabolism (HP:0010901) | 2.10403214 |
| 52 | Congenital stationary night blindness (HP:0007642) | 2.10052747 |
| 53 | Pendular nystagmus (HP:0012043) | 2.09259855 |
| 54 | Renal cortical cysts (HP:0000803) | 2.08542234 |
| 55 | Large for gestational age (HP:0001520) | 2.07715650 |
| 56 | Respiratory failure (HP:0002878) | 2.05772919 |
| 57 | Severe combined immunodeficiency (HP:0004430) | 2.03806126 |
| 58 | B lymphocytopenia (HP:0010976) | 2.03748596 |
| 59 | Abnormality of the ileum (HP:0001549) | 2.01690264 |
| 60 | Abnormality of B cell number (HP:0010975) | 1.98130604 |
| 61 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.97473501 |
| 62 | Bile duct proliferation (HP:0001408) | 1.97039919 |
| 63 | Abnormal biliary tract physiology (HP:0012439) | 1.97039919 |
| 64 | Hyperglycinemia (HP:0002154) | 1.96653552 |
| 65 | Sclerocornea (HP:0000647) | 1.95866211 |
| 66 | Hyperglycinuria (HP:0003108) | 1.94958730 |
| 67 | Respiratory difficulties (HP:0002880) | 1.94497739 |
| 68 | Panhypogammaglobulinemia (HP:0003139) | 1.94123088 |
| 69 | Constricted visual fields (HP:0001133) | 1.92829809 |
| 70 | Meckel diverticulum (HP:0002245) | 1.92471439 |
| 71 | Hypoplasia of the uterus (HP:0000013) | 1.89055245 |
| 72 | Oral leukoplakia (HP:0002745) | 1.88787388 |
| 73 | Abnormality of the prostate (HP:0008775) | 1.86185117 |
| 74 | Homocystinuria (HP:0002156) | 1.86057347 |
| 75 | Abnormality of homocysteine metabolism (HP:0010919) | 1.86057347 |
| 76 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.85693190 |
| 77 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.84441822 |
| 78 | Abnormality of glycolysis (HP:0004366) | 1.83058075 |
| 79 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.82728883 |
| 80 | Cerebral hypomyelination (HP:0006808) | 1.82630029 |
| 81 | Exercise intolerance (HP:0003546) | 1.82409542 |
| 82 | Type 2 muscle fiber atrophy (HP:0003554) | 1.81686310 |
| 83 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.81558443 |
| 84 | Abnormality of the renal medulla (HP:0100957) | 1.78460099 |
| 85 | Carpal bone hypoplasia (HP:0001498) | 1.76897269 |
| 86 | Abnormality of macular pigmentation (HP:0008002) | 1.76649740 |
| 87 | Abnormality of renal resorption (HP:0011038) | 1.76645671 |
| 88 | Increased intramyocellular lipid droplets (HP:0012240) | 1.76286816 |
| 89 | Cellular immunodeficiency (HP:0005374) | 1.76240085 |
| 90 | Increased corneal curvature (HP:0100692) | 1.74037182 |
| 91 | Keratoconus (HP:0000563) | 1.74037182 |
| 92 | Abnormal glycosylation (HP:0012345) | 1.73916351 |
| 93 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.73916351 |
| 94 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.73916351 |
| 95 | Abnormal protein glycosylation (HP:0012346) | 1.73916351 |
| 96 | Progressive inability to walk (HP:0002505) | 1.73787341 |
| 97 | CNS demyelination (HP:0007305) | 1.73261727 |
| 98 | Abnormality of the renal collecting system (HP:0004742) | 1.70465577 |
| 99 | Megaloblastic anemia (HP:0001889) | 1.70041595 |
| 100 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.70021187 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ZAK | 4.62520645 |
| 2 | MST4 | 3.93102238 |
| 3 | MAP4K2 | 3.40896530 |
| 4 | VRK2 | 3.36378384 |
| 5 | EIF2AK3 | 2.90576863 |
| 6 | EIF2AK1 | 2.74515571 |
| 7 | TSSK6 | 2.67851000 |
| 8 | NUAK1 | 2.67687993 |
| 9 | NME1 | 2.54626443 |
| 10 | TLK1 | 2.53170202 |
| 11 | BUB1 | 2.50734709 |
| 12 | PBK | 2.31209302 |
| 13 | MKNK1 | 2.19310376 |
| 14 | VRK1 | 2.15525035 |
| 15 | TRIM28 | 2.07309335 |
| 16 | WNK3 | 1.98420961 |
| 17 | TXK | 1.93022030 |
| 18 | TNIK | 1.87015694 |
| 19 | BMPR1B | 1.81677566 |
| 20 | ADRBK2 | 1.78939043 |
| 21 | TAF1 | 1.74426756 |
| 22 | BCKDK | 1.72555054 |
| 23 | PLK3 | 1.72117821 |
| 24 | TEC | 1.65927170 |
| 25 | PLK4 | 1.61651757 |
| 26 | MAP3K12 | 1.48200885 |
| 27 | SRPK1 | 1.34492211 |
| 28 | MKNK2 | 1.25110994 |
| 29 | GRK1 | 1.22033766 |
| 30 | PASK | 1.20514948 |
| 31 | KDR | 1.13486665 |
| 32 | NEK1 | 1.12004538 |
| 33 | ITK | 1.06431684 |
| 34 | PDK2 | 1.06364367 |
| 35 | RPS6KA4 | 1.04758953 |
| 36 | EIF2AK2 | 0.98922286 |
| 37 | DYRK2 | 0.95930518 |
| 38 | OXSR1 | 0.95026535 |
| 39 | STK38L | 0.93175539 |
| 40 | PLK1 | 0.93033899 |
| 41 | MYLK | 0.90937230 |
| 42 | ERBB3 | 0.89066058 |
| 43 | STK39 | 0.88641764 |
| 44 | PIK3CG | 0.86081294 |
| 45 | CDK8 | 0.84338609 |
| 46 | DAPK1 | 0.83474832 |
| 47 | CDC7 | 0.81071853 |
| 48 | TTK | 0.75726064 |
| 49 | INSRR | 0.75472409 |
| 50 | TGFBR1 | 0.75340774 |
| 51 | MAPKAPK5 | 0.72846594 |
| 52 | WNK4 | 0.70898214 |
| 53 | ATR | 0.69895193 |
| 54 | IKBKB | 0.66557491 |
| 55 | PLK2 | 0.62464259 |
| 56 | PKN1 | 0.59485095 |
| 57 | TIE1 | 0.57891277 |
| 58 | MAPK13 | 0.54817405 |
| 59 | PRKCE | 0.54759348 |
| 60 | AURKB | 0.53958972 |
| 61 | STK16 | 0.53478789 |
| 62 | PAK4 | 0.53154795 |
| 63 | RPS6KA5 | 0.52494395 |
| 64 | STK4 | 0.49602388 |
| 65 | MAP2K6 | 0.48982327 |
| 66 | PINK1 | 0.47689403 |
| 67 | NME2 | 0.44957177 |
| 68 | EPHA3 | 0.44295889 |
| 69 | CHEK2 | 0.43418015 |
| 70 | CSNK2A1 | 0.41464914 |
| 71 | WEE1 | 0.39879783 |
| 72 | FLT3 | 0.39228135 |
| 73 | LIMK1 | 0.39093261 |
| 74 | PRKCQ | 0.38946295 |
| 75 | FRK | 0.38678483 |
| 76 | ALK | 0.37795721 |
| 77 | STK3 | 0.36192707 |
| 78 | MAP2K7 | 0.35074092 |
| 79 | CSNK2A2 | 0.34369023 |
| 80 | IGF1R | 0.32272346 |
| 81 | SYK | 0.31975023 |
| 82 | BTK | 0.29061051 |
| 83 | TAOK3 | 0.28971329 |
| 84 | CSF1R | 0.28824114 |
| 85 | PRKCG | 0.28263006 |
| 86 | GRK5 | 0.27483899 |
| 87 | CSNK1G1 | 0.27093732 |
| 88 | ATM | 0.25860278 |
| 89 | AURKA | 0.25373842 |
| 90 | BCR | 0.24922891 |
| 91 | LYN | 0.24720508 |
| 92 | CSNK1A1 | 0.23249434 |
| 93 | OBSCN | 0.22585741 |
| 94 | DYRK3 | 0.22474382 |
| 95 | LCK | 0.22383176 |
| 96 | ROCK1 | 0.22021504 |
| 97 | PIM1 | 0.21506464 |
| 98 | CSNK1G3 | 0.21421907 |
| 99 | DAPK3 | 0.21030542 |
| 100 | PHKG2 | 0.19551573 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.44821533 |
| 2 | Protein export_Homo sapiens_hsa03060 | 3.38966699 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.84456390 |
| 4 | RNA polymerase_Homo sapiens_hsa03020 | 2.82372276 |
| 5 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.69570154 |
| 6 | Asthma_Homo sapiens_hsa05310 | 2.53364309 |
| 7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.48880790 |
| 8 | Parkinsons disease_Homo sapiens_hsa05012 | 2.42617421 |
| 9 | Allograft rejection_Homo sapiens_hsa05330 | 2.34673606 |
| 10 | Ribosome_Homo sapiens_hsa03010 | 2.17460958 |
| 11 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.09068557 |
| 12 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.05828085 |
| 13 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.98189700 |
| 14 | Basal transcription factors_Homo sapiens_hsa03022 | 1.92140461 |
| 15 | RNA degradation_Homo sapiens_hsa03018 | 1.88438473 |
| 16 | DNA replication_Homo sapiens_hsa03030 | 1.80873745 |
| 17 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.78413931 |
| 18 | Homologous recombination_Homo sapiens_hsa03440 | 1.76729534 |
| 19 | Mismatch repair_Homo sapiens_hsa03430 | 1.75847130 |
| 20 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.73746722 |
| 21 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.71990282 |
| 22 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.66714278 |
| 23 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.64253852 |
| 24 | Base excision repair_Homo sapiens_hsa03410 | 1.62821215 |
| 25 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.58044036 |
| 26 | Huntingtons disease_Homo sapiens_hsa05016 | 1.55347417 |
| 27 | RNA transport_Homo sapiens_hsa03013 | 1.51795584 |
| 28 | Spliceosome_Homo sapiens_hsa03040 | 1.46830678 |
| 29 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.45497303 |
| 30 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.44327004 |
| 31 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.34772000 |
| 32 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.33383805 |
| 33 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.32671857 |
| 34 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.29287219 |
| 35 | Alzheimers disease_Homo sapiens_hsa05010 | 1.28979355 |
| 36 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.26864529 |
| 37 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.23019541 |
| 38 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.22286222 |
| 39 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.19284381 |
| 40 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.17003282 |
| 41 | Purine metabolism_Homo sapiens_hsa00230 | 1.14648121 |
| 42 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.09761039 |
| 43 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.09388601 |
| 44 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.00605295 |
| 45 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.97925418 |
| 46 | Phototransduction_Homo sapiens_hsa04744 | 0.96371459 |
| 47 | Peroxisome_Homo sapiens_hsa04146 | 0.92181797 |
| 48 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.91671328 |
| 49 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.91662031 |
| 50 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.90449484 |
| 51 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.87170719 |
| 52 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.86153367 |
| 53 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.82569837 |
| 54 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.75730782 |
| 55 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.71927038 |
| 56 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.71286301 |
| 57 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.71081207 |
| 58 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.70902191 |
| 59 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.68659445 |
| 60 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.68329269 |
| 61 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.68019654 |
| 62 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.67694826 |
| 63 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.67599917 |
| 64 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.66873902 |
| 65 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.64396324 |
| 66 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.63224363 |
| 67 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.59256286 |
| 68 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.59126624 |
| 69 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.58928324 |
| 70 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.58111593 |
| 71 | Metabolic pathways_Homo sapiens_hsa01100 | 0.56049107 |
| 72 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.55506453 |
| 73 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.55274696 |
| 74 | Olfactory transduction_Homo sapiens_hsa04740 | 0.52157603 |
| 75 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.49373437 |
| 76 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.48568593 |
| 77 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.47290263 |
| 78 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.47118682 |
| 79 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.43824233 |
| 80 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.43268676 |
| 81 | Carbon metabolism_Homo sapiens_hsa01200 | 0.43105853 |
| 82 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.42446877 |
| 83 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.38824933 |
| 84 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.38573444 |
| 85 | Cell cycle_Homo sapiens_hsa04110 | 0.38030262 |
| 86 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.36871761 |
| 87 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.36497787 |
| 88 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.36214783 |
| 89 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.35439488 |
| 90 | Measles_Homo sapiens_hsa05162 | 0.34769792 |
| 91 | Retinol metabolism_Homo sapiens_hsa00830 | 0.32888754 |
| 92 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.30845078 |
| 93 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.30462567 |
| 94 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.29567126 |
| 95 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.29306491 |
| 96 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.29005914 |
| 97 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.26062598 |
| 98 | Taste transduction_Homo sapiens_hsa04742 | 0.26055097 |
| 99 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.23629899 |
| 100 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.23149825 |

