

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | rRNA modification (GO:0000154) | 5.00267570 |
| 2 | rRNA methylation (GO:0031167) | 4.94726267 |
| 3 | ribosomal large subunit biogenesis (GO:0042273) | 4.74937003 |
| 4 | DNA deamination (GO:0045006) | 4.63057270 |
| 5 | proteasome assembly (GO:0043248) | 4.48159229 |
| 6 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.25816107 |
| 7 | ribosomal small subunit assembly (GO:0000028) | 4.24147383 |
| 8 | ATP synthesis coupled proton transport (GO:0015986) | 4.17326632 |
| 9 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.17326632 |
| 10 | GMP metabolic process (GO:0046037) | 3.90079463 |
| 11 | maturation of SSU-rRNA (GO:0030490) | 3.82651214 |
| 12 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.80341713 |
| 13 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.76368580 |
| 14 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.74062982 |
| 15 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.74062982 |
| 16 | protein neddylation (GO:0045116) | 3.74007522 |
| 17 | DNA damage response, detection of DNA damage (GO:0042769) | 3.61262587 |
| 18 | cullin deneddylation (GO:0010388) | 3.58078660 |
| 19 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.55596722 |
| 20 | NADH dehydrogenase complex assembly (GO:0010257) | 3.55596722 |
| 21 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.55596722 |
| 22 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.55256333 |
| 23 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.53534908 |
| 24 | L-fucose catabolic process (GO:0042355) | 3.45717860 |
| 25 | fucose catabolic process (GO:0019317) | 3.45717860 |
| 26 | L-fucose metabolic process (GO:0042354) | 3.45717860 |
| 27 | viral transcription (GO:0019083) | 3.45592144 |
| 28 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.44310983 |
| 29 | translational termination (GO:0006415) | 3.41248049 |
| 30 | protein deneddylation (GO:0000338) | 3.30528591 |
| 31 | protein complex biogenesis (GO:0070271) | 3.30035137 |
| 32 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.29536691 |
| 33 | rRNA catabolic process (GO:0016075) | 3.28715568 |
| 34 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.28025571 |
| 35 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.27484808 |
| 36 | histone mRNA metabolic process (GO:0008334) | 3.25413052 |
| 37 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.23526878 |
| 38 | purine nucleobase biosynthetic process (GO:0009113) | 3.22845633 |
| 39 | cotranslational protein targeting to membrane (GO:0006613) | 3.21231271 |
| 40 | nucleobase biosynthetic process (GO:0046112) | 3.20818323 |
| 41 | protein targeting to ER (GO:0045047) | 3.18609274 |
| 42 | IMP biosynthetic process (GO:0006188) | 3.18592262 |
| 43 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.15109194 |
| 44 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.14776174 |
| 45 | translational elongation (GO:0006414) | 3.09826779 |
| 46 | IMP metabolic process (GO:0046040) | 3.09096685 |
| 47 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.07384789 |
| 48 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.06545536 |
| 49 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.06072453 |
| 50 | chromatin remodeling at centromere (GO:0031055) | 3.04994804 |
| 51 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.04676239 |
| 52 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.04676239 |
| 53 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.04676239 |
| 54 | termination of RNA polymerase III transcription (GO:0006386) | 3.02954900 |
| 55 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.02954900 |
| 56 | rRNA processing (GO:0006364) | 2.99716837 |
| 57 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.99252767 |
| 58 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.99252767 |
| 59 | protein localization to endoplasmic reticulum (GO:0070972) | 2.98659292 |
| 60 | rRNA metabolic process (GO:0016072) | 2.98625283 |
| 61 | protein-cofactor linkage (GO:0018065) | 2.98453000 |
| 62 | translational initiation (GO:0006413) | 2.96460921 |
| 63 | CENP-A containing nucleosome assembly (GO:0034080) | 2.95291883 |
| 64 | ribosome assembly (GO:0042255) | 2.95249799 |
| 65 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.94934785 |
| 66 | negative regulation of ligase activity (GO:0051352) | 2.94665664 |
| 67 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.94665664 |
| 68 | translation (GO:0006412) | 2.94003262 |
| 69 | DNA excision (GO:0044349) | 2.92816175 |
| 70 | nucleotide-excision repair, DNA damage removal (GO:0000718) | 2.92816175 |
| 71 | electron transport chain (GO:0022900) | 2.90489337 |
| 72 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.89667201 |
| 73 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.89488984 |
| 74 | maturation of 5.8S rRNA (GO:0000460) | 2.89201778 |
| 75 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.88955680 |
| 76 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.88955680 |
| 77 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.88836661 |
| 78 | respiratory electron transport chain (GO:0022904) | 2.87745523 |
| 79 | protein K6-linked ubiquitination (GO:0085020) | 2.86243806 |
| 80 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.85758409 |
| 81 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.85067790 |
| 82 | spliceosomal snRNP assembly (GO:0000387) | 2.84146608 |
| 83 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 2.83332814 |
| 84 | regulation of mitochondrial translation (GO:0070129) | 2.82217984 |
| 85 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.80128706 |
| 86 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.80128706 |
| 87 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.80063241 |
| 88 | isotype switching (GO:0045190) | 2.80063241 |
| 89 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.80063241 |
| 90 | mannosylation (GO:0097502) | 2.77773197 |
| 91 | resolution of meiotic recombination intermediates (GO:0000712) | 2.77161755 |
| 92 | tRNA processing (GO:0008033) | 2.76995071 |
| 93 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.74704889 |
| 94 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.74704889 |
| 95 | spliceosomal complex assembly (GO:0000245) | 2.74055027 |
| 96 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.73642955 |
| 97 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.71707045 |
| 98 | DNA replication checkpoint (GO:0000076) | 2.71239822 |
| 99 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.70928484 |
| 100 | transcription from mitochondrial promoter (GO:0006390) | 2.70478026 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.88541084 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.59972531 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.93320032 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.48768227 |
| 5 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.24576144 |
| 6 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.13434033 |
| 7 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.95232121 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.91097601 |
| 9 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.73328967 |
| 10 | VDR_22108803_ChIP-Seq_LS180_Human | 2.71819694 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.66359184 |
| 12 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.61818043 |
| 13 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.60977629 |
| 14 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.58108161 |
| 15 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.48847529 |
| 16 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.47890851 |
| 17 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.41333802 |
| 18 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.32646547 |
| 19 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.32545211 |
| 20 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.30918613 |
| 21 | EWS_26573619_Chip-Seq_HEK293_Human | 2.20281172 |
| 22 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.14364477 |
| 23 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.99614171 |
| 24 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.90053502 |
| 25 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.87911688 |
| 26 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.87728999 |
| 27 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.86697800 |
| 28 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.83234953 |
| 29 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.81551715 |
| 30 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.77156604 |
| 31 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.76579063 |
| 32 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.74288765 |
| 33 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.72828357 |
| 34 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.67187041 |
| 35 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.64982483 |
| 36 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.59404268 |
| 37 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.58139033 |
| 38 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.55799973 |
| 39 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.55433221 |
| 40 | FUS_26573619_Chip-Seq_HEK293_Human | 1.52636193 |
| 41 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.50806871 |
| 42 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.44089150 |
| 43 | P300_19829295_ChIP-Seq_ESCs_Human | 1.43127141 |
| 44 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.42409408 |
| 45 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.40649782 |
| 46 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.38722801 |
| 47 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.32711654 |
| 48 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.32594053 |
| 49 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.32114999 |
| 50 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.31689728 |
| 51 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.31497068 |
| 52 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.28984175 |
| 53 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.27980658 |
| 54 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.24351933 |
| 55 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.21521936 |
| 56 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.21263385 |
| 57 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.21263385 |
| 58 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.19459540 |
| 59 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.19346962 |
| 60 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.17860935 |
| 61 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.17855663 |
| 62 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.17016572 |
| 63 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.16751527 |
| 64 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.16070970 |
| 65 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.14581036 |
| 66 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.14110075 |
| 67 | AR_20517297_ChIP-Seq_VCAP_Human | 1.12972616 |
| 68 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.12961630 |
| 69 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.11207333 |
| 70 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.09453001 |
| 71 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.09453001 |
| 72 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.08988462 |
| 73 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.08527202 |
| 74 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.06808793 |
| 75 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.04789315 |
| 76 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.03942552 |
| 77 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.03628270 |
| 78 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.99182948 |
| 79 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.97711289 |
| 80 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.96719244 |
| 81 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.96644708 |
| 82 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.96259695 |
| 83 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.95517922 |
| 84 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.94317604 |
| 85 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.93342511 |
| 86 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.92672115 |
| 87 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.91653849 |
| 88 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.90516804 |
| 89 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.89451752 |
| 90 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.89420477 |
| 91 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.88282369 |
| 92 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.88282369 |
| 93 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.86950112 |
| 94 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.86452832 |
| 95 | E2F7_22180533_ChIP-Seq_HELA_Human | 0.85453448 |
| 96 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.84696315 |
| 97 | NCOR_22424771_ChIP-Seq_293T_Human | 0.82788963 |
| 98 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.82187626 |
| 99 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.81773419 |
| 100 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.80824394 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006072_abnormal_retinal_apoptosis | 3.42523390 |
| 2 | MP0005646_abnormal_pituitary_gland | 3.12789611 |
| 3 | MP0005645_abnormal_hypothalamus_physiol | 2.95722562 |
| 4 | MP0003693_abnormal_embryo_hatching | 2.94715625 |
| 5 | MP0002102_abnormal_ear_morphology | 2.86067258 |
| 6 | MP0008877_abnormal_DNA_methylation | 2.76990860 |
| 7 | MP0001835_abnormal_antigen_presentation | 2.63429191 |
| 8 | MP0008058_abnormal_DNA_repair | 2.58025101 |
| 9 | MP0003806_abnormal_nucleotide_metabolis | 2.53925556 |
| 10 | MP0006292_abnormal_olfactory_placode | 2.40917364 |
| 11 | MP0003283_abnormal_digestive_organ | 2.24689249 |
| 12 | MP0005084_abnormal_gallbladder_morpholo | 2.23755921 |
| 13 | MP0002234_abnormal_pharynx_morphology | 2.10539903 |
| 14 | MP0005671_abnormal_response_to | 2.07441536 |
| 15 | MP0009697_abnormal_copulation | 2.06784327 |
| 16 | MP0004957_abnormal_blastocyst_morpholog | 2.02949212 |
| 17 | MP0003567_abnormal_fetal_cardiomyocyte | 2.00916161 |
| 18 | MP0010094_abnormal_chromosome_stability | 1.99301141 |
| 19 | MP0005551_abnormal_eye_electrophysiolog | 1.98834177 |
| 20 | MP0001293_anophthalmia | 1.97085542 |
| 21 | MP0009379_abnormal_foot_pigmentation | 1.95354337 |
| 22 | MP0001764_abnormal_homeostasis | 1.95230007 |
| 23 | MP0001873_stomach_inflammation | 1.79428012 |
| 24 | MP0002837_dystrophic_cardiac_calcinosis | 1.70080197 |
| 25 | MP0003786_premature_aging | 1.69423906 |
| 26 | MP0005253_abnormal_eye_physiology | 1.64339926 |
| 27 | MP0008872_abnormal_physiological_respon | 1.54436583 |
| 28 | MP0003195_calcinosis | 1.53127556 |
| 29 | MP0004147_increased_porphyrin_level | 1.50785340 |
| 30 | MP0004885_abnormal_endolymph | 1.47646807 |
| 31 | MP0003011_delayed_dark_adaptation | 1.44089025 |
| 32 | MP0004145_abnormal_muscle_electrophysio | 1.41122167 |
| 33 | MP0003186_abnormal_redox_activity | 1.41085195 |
| 34 | MP0009785_altered_susceptibility_to | 1.37446021 |
| 35 | MP0003718_maternal_effect | 1.36654282 |
| 36 | MP0002736_abnormal_nociception_after | 1.36234301 |
| 37 | MP0006276_abnormal_autonomic_nervous | 1.32984979 |
| 38 | MP0004142_abnormal_muscle_tone | 1.32975882 |
| 39 | MP0006035_abnormal_mitochondrial_morpho | 1.30959579 |
| 40 | MP0004742_abnormal_vestibular_system | 1.28342842 |
| 41 | MP0000631_abnormal_neuroendocrine_gland | 1.27542463 |
| 42 | MP0001501_abnormal_sleep_pattern | 1.21769179 |
| 43 | MP0001853_heart_inflammation | 1.21262897 |
| 44 | MP0002751_abnormal_autonomic_nervous | 1.18796165 |
| 45 | MP0005387_immune_system_phenotype | 1.16664594 |
| 46 | MP0001790_abnormal_immune_system | 1.16664594 |
| 47 | MP0006036_abnormal_mitochondrial_physio | 1.15519969 |
| 48 | MP0008875_abnormal_xenobiotic_pharmacok | 1.15265890 |
| 49 | MP0009333_abnormal_splenocyte_physiolog | 1.13697519 |
| 50 | MP0002148_abnormal_hypersensitivity_rea | 1.12847795 |
| 51 | MP0003111_abnormal_nucleus_morphology | 1.08053730 |
| 52 | MP0005377_hearing/vestibular/ear_phenot | 1.06974025 |
| 53 | MP0003878_abnormal_ear_physiology | 1.06974025 |
| 54 | MP0001529_abnormal_vocalization | 1.06308163 |
| 55 | MP0001881_abnormal_mammary_gland | 1.05009104 |
| 56 | MP0004782_abnormal_surfactant_physiolog | 1.04492565 |
| 57 | MP0008932_abnormal_embryonic_tissue | 0.99726547 |
| 58 | MP0001968_abnormal_touch/_nociception | 0.99435596 |
| 59 | MP0000049_abnormal_middle_ear | 0.97119576 |
| 60 | MP0003880_abnormal_central_pattern | 0.96831948 |
| 61 | MP0008007_abnormal_cellular_replicative | 0.95591605 |
| 62 | MP0005332_abnormal_amino_acid | 0.94443547 |
| 63 | MP0001485_abnormal_pinna_reflex | 0.93796512 |
| 64 | MP0005389_reproductive_system_phenotype | 0.93254019 |
| 65 | MP0003077_abnormal_cell_cycle | 0.89377691 |
| 66 | MP0001986_abnormal_taste_sensitivity | 0.88499928 |
| 67 | MP0005410_abnormal_fertilization | 0.88167684 |
| 68 | MP0000685_abnormal_immune_system | 0.86447757 |
| 69 | MP0010155_abnormal_intestine_physiology | 0.84409234 |
| 70 | MP0003045_fibrosis | 0.83786422 |
| 71 | MP0001919_abnormal_reproductive_system | 0.82519275 |
| 72 | MP0001984_abnormal_olfaction | 0.82453272 |
| 73 | MP0005083_abnormal_biliary_tract | 0.82150394 |
| 74 | MP0001929_abnormal_gametogenesis | 0.80920517 |
| 75 | MP0002282_abnormal_trachea_morphology | 0.80228824 |
| 76 | MP0003119_abnormal_digestive_system | 0.80178409 |
| 77 | MP0009765_abnormal_xenobiotic_induced | 0.78632241 |
| 78 | MP0005085_abnormal_gallbladder_physiolo | 0.78402955 |
| 79 | MP0002277_abnormal_respiratory_mucosa | 0.78256065 |
| 80 | MP0002210_abnormal_sex_determination | 0.78247283 |
| 81 | MP0004215_abnormal_myocardial_fiber | 0.77878273 |
| 82 | MP0005636_abnormal_mineral_homeostasis | 0.77368050 |
| 83 | MP0002138_abnormal_hepatobiliary_system | 0.77146259 |
| 84 | MP0008789_abnormal_olfactory_epithelium | 0.76757713 |
| 85 | MP0008995_early_reproductive_senescence | 0.76122979 |
| 86 | MP0004019_abnormal_vitamin_homeostasis | 0.74426534 |
| 87 | MP0001800_abnormal_humoral_immune | 0.73400658 |
| 88 | MP0002006_tumorigenesis | 0.73089174 |
| 89 | MP0001286_abnormal_eye_development | 0.70039701 |
| 90 | MP0002019_abnormal_tumor_incidence | 0.69910327 |
| 91 | MP0002405_respiratory_system_inflammati | 0.69096061 |
| 92 | MP0005391_vision/eye_phenotype | 0.69066879 |
| 93 | MP0005195_abnormal_posterior_eye | 0.68312173 |
| 94 | MP0000653_abnormal_sex_gland | 0.68305760 |
| 95 | MP0008775_abnormal_heart_ventricle | 0.66332827 |
| 96 | MP0001119_abnormal_female_reproductive | 0.66064029 |
| 97 | MP0009764_decreased_sensitivity_to | 0.65318232 |
| 98 | MP0005000_abnormal_immune_tolerance | 0.64620422 |
| 99 | MP0003698_abnormal_male_reproductive | 0.64571696 |
| 100 | MP0002272_abnormal_nervous_system | 0.62631717 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.24534364 |
| 2 | Acute encephalopathy (HP:0006846) | 3.87736938 |
| 3 | Mitochondrial inheritance (HP:0001427) | 3.74116202 |
| 4 | Methylmalonic acidemia (HP:0002912) | 3.68432815 |
| 5 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.66398254 |
| 6 | Congenital, generalized hypertrichosis (HP:0004540) | 3.54747945 |
| 7 | Stomatitis (HP:0010280) | 3.53484228 |
| 8 | Progressive macrocephaly (HP:0004481) | 3.50978512 |
| 9 | Increased CSF lactate (HP:0002490) | 3.38539191 |
| 10 | Hypoproteinemia (HP:0003075) | 3.36365731 |
| 11 | Type I transferrin isoform profile (HP:0003642) | 3.05868172 |
| 12 | Hepatocellular necrosis (HP:0001404) | 3.03409169 |
| 13 | Cerebral edema (HP:0002181) | 3.00523398 |
| 14 | Colon cancer (HP:0003003) | 2.99806326 |
| 15 | Pancreatic cysts (HP:0001737) | 2.95217291 |
| 16 | Increased hepatocellular lipid droplets (HP:0006565) | 2.87821347 |
| 17 | Panhypogammaglobulinemia (HP:0003139) | 2.87531784 |
| 18 | Increased serum pyruvate (HP:0003542) | 2.86041582 |
| 19 | Hepatic necrosis (HP:0002605) | 2.85036557 |
| 20 | Methylmalonic aciduria (HP:0012120) | 2.76901874 |
| 21 | Nephronophthisis (HP:0000090) | 2.76134882 |
| 22 | Attenuation of retinal blood vessels (HP:0007843) | 2.74221348 |
| 23 | IgG deficiency (HP:0004315) | 2.72092043 |
| 24 | Renal cortical cysts (HP:0000803) | 2.71387667 |
| 25 | Hyperglycinemia (HP:0002154) | 2.69556087 |
| 26 | Hypoplasia of the pons (HP:0012110) | 2.68062406 |
| 27 | Optic disc pallor (HP:0000543) | 2.60649120 |
| 28 | Abnormality of the pons (HP:0007361) | 2.59577087 |
| 29 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.59090152 |
| 30 | B lymphocytopenia (HP:0010976) | 2.53333837 |
| 31 | Lipid accumulation in hepatocytes (HP:0006561) | 2.50739836 |
| 32 | Abnormality of the renal cortex (HP:0011035) | 2.49712912 |
| 33 | Molar tooth sign on MRI (HP:0002419) | 2.49399368 |
| 34 | Abnormality of midbrain morphology (HP:0002418) | 2.49399368 |
| 35 | Abnormal number of erythroid precursors (HP:0012131) | 2.48076367 |
| 36 | Increased serum lactate (HP:0002151) | 2.47227416 |
| 37 | Abnormality of alanine metabolism (HP:0010916) | 2.46947659 |
| 38 | Hyperalaninemia (HP:0003348) | 2.46947659 |
| 39 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.46947659 |
| 40 | Abnormality of DNA repair (HP:0003254) | 2.46069560 |
| 41 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.44663969 |
| 42 | 3-Methylglutaconic aciduria (HP:0003535) | 2.43555624 |
| 43 | Reduced antithrombin III activity (HP:0001976) | 2.42970102 |
| 44 | Congenital stationary night blindness (HP:0007642) | 2.41589964 |
| 45 | Meckel diverticulum (HP:0002245) | 2.41381542 |
| 46 | Type 2 muscle fiber atrophy (HP:0003554) | 2.39835394 |
| 47 | Reticulocytopenia (HP:0001896) | 2.37385919 |
| 48 | Abnormality of the ileum (HP:0001549) | 2.37236817 |
| 49 | Pendular nystagmus (HP:0012043) | 2.36567451 |
| 50 | Lactic acidosis (HP:0003128) | 2.32451591 |
| 51 | Pancreatic fibrosis (HP:0100732) | 2.32272559 |
| 52 | Hypochromic microcytic anemia (HP:0004840) | 2.31143288 |
| 53 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.30062493 |
| 54 | Abnormality of B cell number (HP:0010975) | 2.29717625 |
| 55 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.29118499 |
| 56 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.29118499 |
| 57 | Abnormal protein glycosylation (HP:0012346) | 2.29118499 |
| 58 | Abnormal glycosylation (HP:0012345) | 2.29118499 |
| 59 | Triphalangeal thumb (HP:0001199) | 2.26329420 |
| 60 | True hermaphroditism (HP:0010459) | 2.26161120 |
| 61 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.23801890 |
| 62 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.23787733 |
| 63 | Hyperglycinuria (HP:0003108) | 2.22224045 |
| 64 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.22163628 |
| 65 | Macrocytic anemia (HP:0001972) | 2.22160386 |
| 66 | Bilateral microphthalmos (HP:0007633) | 2.21337724 |
| 67 | Abnormality of glycolysis (HP:0004366) | 2.20732857 |
| 68 | Abnormality of glycine metabolism (HP:0010895) | 2.20384500 |
| 69 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.20384500 |
| 70 | Abolished electroretinogram (ERG) (HP:0000550) | 2.19518170 |
| 71 | Microvesicular hepatic steatosis (HP:0001414) | 2.17433908 |
| 72 | Abnormality of serum amino acid levels (HP:0003112) | 2.17055561 |
| 73 | Renal Fanconi syndrome (HP:0001994) | 2.11518164 |
| 74 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.09574499 |
| 75 | Abnormality of the renal medulla (HP:0100957) | 2.09451005 |
| 76 | Leukodystrophy (HP:0002415) | 2.08250793 |
| 77 | Lethargy (HP:0001254) | 2.06469862 |
| 78 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.06081718 |
| 79 | Cleft eyelid (HP:0000625) | 2.01477586 |
| 80 | Absent thumb (HP:0009777) | 2.01426372 |
| 81 | Aplastic anemia (HP:0001915) | 2.00573425 |
| 82 | Exercise intolerance (HP:0003546) | 1.99838928 |
| 83 | Respiratory failure (HP:0002878) | 1.97809302 |
| 84 | Exertional dyspnea (HP:0002875) | 1.96065976 |
| 85 | Constricted visual fields (HP:0001133) | 1.95199111 |
| 86 | Abnormality of methionine metabolism (HP:0010901) | 1.93482469 |
| 87 | Abnormality of vitamin B metabolism (HP:0004340) | 1.92712502 |
| 88 | Medial flaring of the eyebrow (HP:0010747) | 1.91815438 |
| 89 | Abnormal pupillary function (HP:0007686) | 1.91504681 |
| 90 | Muscle fiber atrophy (HP:0100295) | 1.88690173 |
| 91 | Bile duct proliferation (HP:0001408) | 1.83354950 |
| 92 | Abnormal biliary tract physiology (HP:0012439) | 1.83354950 |
| 93 | Dyschromatopsia (HP:0007641) | 1.80148014 |
| 94 | Tubular atrophy (HP:0000092) | 1.74578383 |
| 95 | Pancytopenia (HP:0001876) | 1.74295069 |
| 96 | Abnormality of the preputium (HP:0100587) | 1.73996626 |
| 97 | Severe combined immunodeficiency (HP:0004430) | 1.73933951 |
| 98 | Chorioretinal atrophy (HP:0000533) | 1.72727153 |
| 99 | Duodenal stenosis (HP:0100867) | 1.70887450 |
| 100 | Small intestinal stenosis (HP:0012848) | 1.70887450 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 3.77537885 |
| 2 | ZAK | 3.14007586 |
| 3 | NUAK1 | 3.04654497 |
| 4 | VRK2 | 3.01818559 |
| 5 | EIF2AK3 | 2.55304201 |
| 6 | SRPK1 | 2.27010960 |
| 7 | MKNK1 | 2.25424091 |
| 8 | NME1 | 2.24967291 |
| 9 | NEK9 | 2.21265055 |
| 10 | VRK1 | 2.15679088 |
| 11 | WNK3 | 2.13945557 |
| 12 | TLK1 | 2.13931453 |
| 13 | TSSK6 | 2.13598724 |
| 14 | BUB1 | 2.11076354 |
| 15 | TRIM28 | 2.09248729 |
| 16 | TAF1 | 2.04847571 |
| 17 | NEK1 | 2.02832133 |
| 18 | CDK19 | 1.96971144 |
| 19 | PLK3 | 1.77630554 |
| 20 | TEC | 1.70777919 |
| 21 | BCKDK | 1.70210615 |
| 22 | BMPR1B | 1.70161504 |
| 23 | MST4 | 1.59908662 |
| 24 | RPS6KA4 | 1.56628299 |
| 25 | ADRBK2 | 1.56177971 |
| 26 | GRK1 | 1.55743064 |
| 27 | PLK4 | 1.50231556 |
| 28 | TIE1 | 1.41077406 |
| 29 | PASK | 1.37290148 |
| 30 | CDC7 | 1.34638665 |
| 31 | MAP4K2 | 1.33397253 |
| 32 | STK16 | 1.32296619 |
| 33 | PBK | 1.29642862 |
| 34 | TAOK3 | 1.26642398 |
| 35 | EIF2AK2 | 1.21734802 |
| 36 | MAP4K1 | 1.18557811 |
| 37 | BCR | 1.15421210 |
| 38 | CSNK1G3 | 1.14016580 |
| 39 | MKNK2 | 1.13593910 |
| 40 | FES | 1.11480617 |
| 41 | CSNK1G2 | 1.08159054 |
| 42 | DYRK2 | 1.06767431 |
| 43 | OXSR1 | 1.03741993 |
| 44 | TNIK | 1.01619666 |
| 45 | CSNK1G1 | 1.01097857 |
| 46 | IKBKB | 0.95138647 |
| 47 | RPS6KA5 | 0.93048414 |
| 48 | TNK2 | 0.92644316 |
| 49 | CAMKK2 | 0.90689540 |
| 50 | CSNK1A1L | 0.89510378 |
| 51 | ITK | 0.88408273 |
| 52 | PINK1 | 0.88087778 |
| 53 | PLK1 | 0.86807146 |
| 54 | STK38L | 0.83775279 |
| 55 | ACVR1B | 0.81386272 |
| 56 | TGFBR1 | 0.72735096 |
| 57 | MAPK13 | 0.71371748 |
| 58 | FRK | 0.70332743 |
| 59 | NME2 | 0.69652637 |
| 60 | SYK | 0.69230869 |
| 61 | GRK7 | 0.68830202 |
| 62 | NEK2 | 0.65573070 |
| 63 | ATR | 0.65031001 |
| 64 | PLK2 | 0.64897088 |
| 65 | TTK | 0.63363257 |
| 66 | CDK3 | 0.59600187 |
| 67 | MAP2K6 | 0.58936265 |
| 68 | PRKCQ | 0.57101068 |
| 69 | CSNK2A2 | 0.56617124 |
| 70 | IKBKE | 0.56084312 |
| 71 | INSRR | 0.55833141 |
| 72 | PRKCE | 0.55255882 |
| 73 | AURKB | 0.53533845 |
| 74 | ALK | 0.53491288 |
| 75 | LYN | 0.51545727 |
| 76 | CSNK2A1 | 0.49953072 |
| 77 | BTK | 0.49516873 |
| 78 | BRSK2 | 0.48815649 |
| 79 | WNK4 | 0.47483561 |
| 80 | CSNK1A1 | 0.46926480 |
| 81 | PTK2B | 0.45567082 |
| 82 | MAPKAPK5 | 0.45523744 |
| 83 | EIF2AK1 | 0.45427732 |
| 84 | ADRBK1 | 0.44984348 |
| 85 | KDR | 0.40060013 |
| 86 | ATM | 0.38205228 |
| 87 | PIK3CA | 0.36834267 |
| 88 | IGF1R | 0.36672628 |
| 89 | WEE1 | 0.36542537 |
| 90 | FLT3 | 0.36354162 |
| 91 | PAK3 | 0.35650445 |
| 92 | MUSK | 0.33531514 |
| 93 | CHEK2 | 0.31775083 |
| 94 | MAP2K7 | 0.31087844 |
| 95 | LCK | 0.30461222 |
| 96 | KIT | 0.30346601 |
| 97 | PRKACA | 0.30190744 |
| 98 | CAMK1 | 0.29918894 |
| 99 | OBSCN | 0.27330061 |
| 100 | CSF1R | 0.26893415 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.25475060 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 3.42483232 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.97409811 |
| 4 | Protein export_Homo sapiens_hsa03060 | 2.94272884 |
| 5 | Mismatch repair_Homo sapiens_hsa03430 | 2.59352858 |
| 6 | Parkinsons disease_Homo sapiens_hsa05012 | 2.52924998 |
| 7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.46062792 |
| 8 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.45416288 |
| 9 | Homologous recombination_Homo sapiens_hsa03440 | 2.39635594 |
| 10 | RNA polymerase_Homo sapiens_hsa03020 | 2.21879434 |
| 11 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.08718650 |
| 12 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.06997072 |
| 13 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.05412328 |
| 14 | Phototransduction_Homo sapiens_hsa04744 | 1.96491180 |
| 15 | DNA replication_Homo sapiens_hsa03030 | 1.96425361 |
| 16 | Allograft rejection_Homo sapiens_hsa05330 | 1.93007738 |
| 17 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.86295356 |
| 18 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.82087918 |
| 19 | RNA degradation_Homo sapiens_hsa03018 | 1.79860749 |
| 20 | Spliceosome_Homo sapiens_hsa03040 | 1.77939924 |
| 21 | Basal transcription factors_Homo sapiens_hsa03022 | 1.72860729 |
| 22 | Asthma_Homo sapiens_hsa05310 | 1.65236084 |
| 23 | Huntingtons disease_Homo sapiens_hsa05016 | 1.65204118 |
| 24 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.63508282 |
| 25 | RNA transport_Homo sapiens_hsa03013 | 1.59438429 |
| 26 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.56622118 |
| 27 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.55279693 |
| 28 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.52373862 |
| 29 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.45958658 |
| 30 | Base excision repair_Homo sapiens_hsa03410 | 1.45468673 |
| 31 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.39667571 |
| 32 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.37399195 |
| 33 | Alzheimers disease_Homo sapiens_hsa05010 | 1.31893410 |
| 34 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.30661041 |
| 35 | Sulfur relay system_Homo sapiens_hsa04122 | 1.30236060 |
| 36 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.29546987 |
| 37 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.29223128 |
| 38 | Purine metabolism_Homo sapiens_hsa00230 | 1.26371250 |
| 39 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.24351272 |
| 40 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.21025812 |
| 41 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.18581894 |
| 42 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.12807444 |
| 43 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.12103239 |
| 44 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.09778691 |
| 45 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.05095602 |
| 46 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.93801609 |
| 47 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.91406883 |
| 48 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.86837496 |
| 49 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.86493791 |
| 50 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.86450699 |
| 51 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.86169957 |
| 52 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.82891681 |
| 53 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.80673617 |
| 54 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.79557206 |
| 55 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.78700255 |
| 56 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.77192873 |
| 57 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.75887797 |
| 58 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.75737998 |
| 59 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.75664098 |
| 60 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.73067289 |
| 61 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.69468388 |
| 62 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.65020275 |
| 63 | Peroxisome_Homo sapiens_hsa04146 | 0.64272657 |
| 64 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.63017056 |
| 65 | Olfactory transduction_Homo sapiens_hsa04740 | 0.60965601 |
| 66 | Metabolic pathways_Homo sapiens_hsa01100 | 0.60878070 |
| 67 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.57856206 |
| 68 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.56447612 |
| 69 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.53673322 |
| 70 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.52958083 |
| 71 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.52511995 |
| 72 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.52464525 |
| 73 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.49835409 |
| 74 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.48743076 |
| 75 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.48238872 |
| 76 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.47020435 |
| 77 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.46621989 |
| 78 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.46225655 |
| 79 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.46171193 |
| 80 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.45985117 |
| 81 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.44235105 |
| 82 | Retinol metabolism_Homo sapiens_hsa00830 | 0.42749184 |
| 83 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.42279062 |
| 84 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.40520715 |
| 85 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.40108062 |
| 86 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.38374300 |
| 87 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.38134437 |
| 88 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.34332038 |
| 89 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.33756597 |
| 90 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.32821114 |
| 91 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.32245152 |
| 92 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.31807609 |
| 93 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.31595116 |
| 94 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.31542648 |
| 95 | Carbon metabolism_Homo sapiens_hsa01200 | 0.29003438 |
| 96 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.27811834 |
| 97 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.22556174 |
| 98 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.22288639 |
| 99 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.20440995 |
| 100 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.19646171 |

