

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | chaperone-mediated protein transport (GO:0072321) | 5.76781279 |
| 2 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.88291423 |
| 3 | DNA deamination (GO:0045006) | 4.87450626 |
| 4 | proteasome assembly (GO:0043248) | 4.63236531 |
| 5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.38833874 |
| 6 | ATP synthesis coupled proton transport (GO:0015986) | 4.38833874 |
| 7 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.34761355 |
| 8 | pseudouridine synthesis (GO:0001522) | 4.24055058 |
| 9 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.14422667 |
| 10 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.14422667 |
| 11 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.96187532 |
| 12 | base-excision repair, AP site formation (GO:0006285) | 3.91547287 |
| 13 | kinetochore assembly (GO:0051382) | 3.88549967 |
| 14 | protein deneddylation (GO:0000338) | 3.86758890 |
| 15 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.75354319 |
| 16 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.72124445 |
| 17 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.71989620 |
| 18 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.66250318 |
| 19 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.64091803 |
| 20 | NADH dehydrogenase complex assembly (GO:0010257) | 3.64091803 |
| 21 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.64091803 |
| 22 | cullin deneddylation (GO:0010388) | 3.58323568 |
| 23 | protein complex biogenesis (GO:0070271) | 3.55158764 |
| 24 | protein neddylation (GO:0045116) | 3.48419232 |
| 25 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.45950088 |
| 26 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.44864283 |
| 27 | inner mitochondrial membrane organization (GO:0007007) | 3.43499887 |
| 28 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.42750494 |
| 29 | termination of RNA polymerase III transcription (GO:0006386) | 3.42750494 |
| 30 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.38755770 |
| 31 | respiratory chain complex IV assembly (GO:0008535) | 3.36229457 |
| 32 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.33715641 |
| 33 | regulation of chronic inflammatory response (GO:0002676) | 3.29641243 |
| 34 | kinetochore organization (GO:0051383) | 3.27753171 |
| 35 | rRNA modification (GO:0000154) | 3.14325729 |
| 36 | metaphase plate congression (GO:0051310) | 3.13875414 |
| 37 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.13844753 |
| 38 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.13844753 |
| 39 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.13844753 |
| 40 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.13526576 |
| 41 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.13307964 |
| 42 | negative regulation of ligase activity (GO:0051352) | 3.07249498 |
| 43 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.07249498 |
| 44 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.06032296 |
| 45 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.05230359 |
| 46 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.05230359 |
| 47 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.03639643 |
| 48 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.03639643 |
| 49 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.02416463 |
| 50 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.02416463 |
| 51 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.99934695 |
| 52 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.99503212 |
| 53 | RNA destabilization (GO:0050779) | 2.99352247 |
| 54 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 2.98074703 |
| 55 | GTP biosynthetic process (GO:0006183) | 2.97724948 |
| 56 | nucleotide transmembrane transport (GO:1901679) | 2.97684440 |
| 57 | aldehyde catabolic process (GO:0046185) | 2.96360997 |
| 58 | termination of RNA polymerase I transcription (GO:0006363) | 2.95368957 |
| 59 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.93790376 |
| 60 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.93621411 |
| 61 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.92150912 |
| 62 | ribosome assembly (GO:0042255) | 2.91206872 |
| 63 | protein K6-linked ubiquitination (GO:0085020) | 2.88832526 |
| 64 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 2.88478686 |
| 65 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.87216114 |
| 66 | positive regulation of ligase activity (GO:0051351) | 2.85682293 |
| 67 | DNA double-strand break processing (GO:0000729) | 2.83976111 |
| 68 | protein-cofactor linkage (GO:0018065) | 2.83286573 |
| 69 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.82619462 |
| 70 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.82456771 |
| 71 | isotype switching (GO:0045190) | 2.82456771 |
| 72 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.82456771 |
| 73 | replication fork processing (GO:0031297) | 2.82448257 |
| 74 | mitotic metaphase plate congression (GO:0007080) | 2.82437915 |
| 75 | tRNA processing (GO:0008033) | 2.80041285 |
| 76 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.80038491 |
| 77 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.80038491 |
| 78 | rRNA catabolic process (GO:0016075) | 2.79978214 |
| 79 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.78536967 |
| 80 | protein targeting to mitochondrion (GO:0006626) | 2.76995577 |
| 81 | chromatin remodeling at centromere (GO:0031055) | 2.76737147 |
| 82 | cytochrome complex assembly (GO:0017004) | 2.76653973 |
| 83 | positive regulation of prostaglandin secretion (GO:0032308) | 2.76380807 |
| 84 | ribosomal small subunit assembly (GO:0000028) | 2.76184905 |
| 85 | CENP-A containing nucleosome assembly (GO:0034080) | 2.75516419 |
| 86 | DNA damage response, detection of DNA damage (GO:0042769) | 2.74000850 |
| 87 | maturation of SSU-rRNA (GO:0030490) | 2.72080459 |
| 88 | respiratory electron transport chain (GO:0022904) | 2.71693528 |
| 89 | transcription from RNA polymerase I promoter (GO:0006360) | 2.69497363 |
| 90 | electron transport chain (GO:0022900) | 2.69282443 |
| 91 | AMP metabolic process (GO:0046033) | 2.67552406 |
| 92 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.66582328 |
| 93 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.66481664 |
| 94 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 2.66298334 |
| 95 | adenosine metabolic process (GO:0046085) | 2.63352688 |
| 96 | regulation of meiosis I (GO:0060631) | 2.62946466 |
| 97 | tRNA metabolic process (GO:0006399) | 2.62525145 |
| 98 | rRNA methylation (GO:0031167) | 2.62054239 |
| 99 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.61735844 |
| 100 | interferon-gamma production (GO:0032609) | 2.61703271 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.06240231 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.63104318 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.22689301 |
| 4 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 4.04599752 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.25655916 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.25223768 |
| 7 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.23372917 |
| 8 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.18154509 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.95849325 |
| 10 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.80218657 |
| 11 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.69631369 |
| 12 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.68908099 |
| 13 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.59615834 |
| 14 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.50940112 |
| 15 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.50258471 |
| 16 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.45303725 |
| 17 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.35256520 |
| 18 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.34916881 |
| 19 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.23584938 |
| 20 | VDR_22108803_ChIP-Seq_LS180_Human | 2.23201606 |
| 21 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.13882751 |
| 22 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.12441462 |
| 23 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.08034150 |
| 24 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.07817679 |
| 25 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.06514911 |
| 26 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.01557141 |
| 27 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.99970395 |
| 28 | EWS_26573619_Chip-Seq_HEK293_Human | 1.99120311 |
| 29 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.71694424 |
| 30 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.69788414 |
| 31 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.59293876 |
| 32 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.59110232 |
| 33 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.56374682 |
| 34 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.55297007 |
| 35 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.49817269 |
| 36 | FUS_26573619_Chip-Seq_HEK293_Human | 1.44414828 |
| 37 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.44309762 |
| 38 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.40525357 |
| 39 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.40319494 |
| 40 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.35090777 |
| 41 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.34991911 |
| 42 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.34401615 |
| 43 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.33459713 |
| 44 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.29773108 |
| 45 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.29205104 |
| 46 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.29140796 |
| 47 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.28693356 |
| 48 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.28210944 |
| 49 | AR_20517297_ChIP-Seq_VCAP_Human | 1.26239769 |
| 50 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.24955211 |
| 51 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.23417908 |
| 52 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.23214410 |
| 53 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.22480970 |
| 54 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.22182353 |
| 55 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.21136351 |
| 56 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.20790857 |
| 57 | GATA3_26560356_Chip-Seq_TH2_Human | 1.20224462 |
| 58 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.19006987 |
| 59 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.17043156 |
| 60 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.16982916 |
| 61 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.16813098 |
| 62 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.16126522 |
| 63 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.14783029 |
| 64 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.14783029 |
| 65 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.13925444 |
| 66 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.13913782 |
| 67 | NCOR_22424771_ChIP-Seq_293T_Human | 1.13344637 |
| 68 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.13146066 |
| 69 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.12299145 |
| 70 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.10921430 |
| 71 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.10530427 |
| 72 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.08144662 |
| 73 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.06290420 |
| 74 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.04367846 |
| 75 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.03133194 |
| 76 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.01539771 |
| 77 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.01078537 |
| 78 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.98967284 |
| 79 | P300_19829295_ChIP-Seq_ESCs_Human | 0.98109789 |
| 80 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.96467893 |
| 81 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.95780548 |
| 82 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.94195003 |
| 83 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.94195003 |
| 84 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.93745145 |
| 85 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.91172072 |
| 86 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.91172072 |
| 87 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.90343174 |
| 88 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.90289457 |
| 89 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.88335589 |
| 90 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.88243115 |
| 91 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.88087689 |
| 92 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.87456636 |
| 93 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.87241072 |
| 94 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.86081396 |
| 95 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.86033593 |
| 96 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.85937821 |
| 97 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.85789591 |
| 98 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.85514875 |
| 99 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.82572018 |
| 100 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.81948365 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008058_abnormal_DNA_repair | 3.88664071 |
| 2 | MP0008877_abnormal_DNA_methylation | 3.76048187 |
| 3 | MP0001348_abnormal_lacrimal_gland | 2.87384136 |
| 4 | MP0002102_abnormal_ear_morphology | 2.70122354 |
| 5 | MP0003693_abnormal_embryo_hatching | 2.52104325 |
| 6 | MP0008875_abnormal_xenobiotic_pharmacok | 2.47867928 |
| 7 | MP0008872_abnormal_physiological_respon | 2.46748587 |
| 8 | MP0003806_abnormal_nucleotide_metabolis | 2.41418305 |
| 9 | MP0001986_abnormal_taste_sensitivity | 2.29519569 |
| 10 | MP0002736_abnormal_nociception_after | 2.25156918 |
| 11 | MP0002837_dystrophic_cardiac_calcinosis | 2.20741171 |
| 12 | MP0005671_abnormal_response_to | 2.16677211 |
| 13 | MP0001835_abnormal_antigen_presentation | 2.12627707 |
| 14 | MP0006072_abnormal_retinal_apoptosis | 2.05177460 |
| 15 | MP0003786_premature_aging | 1.91375352 |
| 16 | MP0010094_abnormal_chromosome_stability | 1.91305049 |
| 17 | MP0005646_abnormal_pituitary_gland | 1.77459041 |
| 18 | MP0003077_abnormal_cell_cycle | 1.77165901 |
| 19 | MP0003283_abnormal_digestive_organ | 1.75014000 |
| 20 | MP0002163_abnormal_gland_morphology | 1.73974857 |
| 21 | MP0003111_abnormal_nucleus_morphology | 1.72357750 |
| 22 | MP0001968_abnormal_touch/_nociception | 1.70008160 |
| 23 | MP0003718_maternal_effect | 1.65224452 |
| 24 | MP0005423_abnormal_somatic_nervous | 1.63294556 |
| 25 | MP0004957_abnormal_blastocyst_morpholog | 1.61335047 |
| 26 | MP0002006_tumorigenesis | 1.59564009 |
| 27 | MP0003011_delayed_dark_adaptation | 1.57984862 |
| 28 | MP0001984_abnormal_olfaction | 1.56968221 |
| 29 | MP0003195_calcinosis | 1.54274252 |
| 30 | MP0000566_synostosis | 1.48168920 |
| 31 | MP0005084_abnormal_gallbladder_morpholo | 1.42164924 |
| 32 | MP0006292_abnormal_olfactory_placode | 1.38656123 |
| 33 | MP0000427_abnormal_hair_cycle | 1.38489858 |
| 34 | MP0005551_abnormal_eye_electrophysiolog | 1.37578687 |
| 35 | MP0005379_endocrine/exocrine_gland_phen | 1.37249154 |
| 36 | MP0000685_abnormal_immune_system | 1.32491464 |
| 37 | MP0003186_abnormal_redox_activity | 1.31633630 |
| 38 | MP0005310_abnormal_salivary_gland | 1.30079150 |
| 39 | MP0006036_abnormal_mitochondrial_physio | 1.29475941 |
| 40 | MP0001764_abnormal_homeostasis | 1.28038127 |
| 41 | MP0004145_abnormal_muscle_electrophysio | 1.26815697 |
| 42 | MP0001800_abnormal_humoral_immune | 1.23818697 |
| 43 | MP0000372_irregular_coat_pigmentation | 1.21143501 |
| 44 | MP0001293_anophthalmia | 1.16838209 |
| 45 | MP0005389_reproductive_system_phenotype | 1.16586064 |
| 46 | MP0002160_abnormal_reproductive_system | 1.14142881 |
| 47 | MP0003045_fibrosis | 1.13781430 |
| 48 | MP0009785_altered_susceptibility_to | 1.08702473 |
| 49 | MP0002148_abnormal_hypersensitivity_rea | 1.08587214 |
| 50 | MP0009333_abnormal_splenocyte_physiolog | 1.07881392 |
| 51 | MP0004142_abnormal_muscle_tone | 1.07717559 |
| 52 | MP0000383_abnormal_hair_follicle | 1.07322918 |
| 53 | MP0009745_abnormal_behavioral_response | 1.06452663 |
| 54 | MP0001873_stomach_inflammation | 1.06356320 |
| 55 | MP0002166_altered_tumor_susceptibility | 1.05655132 |
| 56 | MP0001929_abnormal_gametogenesis | 1.05460783 |
| 57 | MP0008995_early_reproductive_senescence | 1.02322892 |
| 58 | MP0002876_abnormal_thyroid_physiology | 1.01842574 |
| 59 | MP0003646_muscle_fatigue | 1.00658950 |
| 60 | MP0002938_white_spotting | 1.00433766 |
| 61 | MP0001919_abnormal_reproductive_system | 0.99543525 |
| 62 | MP0005000_abnormal_immune_tolerance | 0.98878590 |
| 63 | MP0004215_abnormal_myocardial_fiber | 0.98348566 |
| 64 | MP0000613_abnormal_salivary_gland | 0.97117704 |
| 65 | MP0003763_abnormal_thymus_physiology | 0.93790250 |
| 66 | MP0002723_abnormal_immune_serum | 0.93411426 |
| 67 | MP0008775_abnormal_heart_ventricle | 0.93063975 |
| 68 | MP0002210_abnormal_sex_determination | 0.92501385 |
| 69 | MP0005253_abnormal_eye_physiology | 0.91314534 |
| 70 | MP0008007_abnormal_cellular_replicative | 0.90715092 |
| 71 | MP0002277_abnormal_respiratory_mucosa | 0.89921183 |
| 72 | MP0001529_abnormal_vocalization | 0.88340948 |
| 73 | MP0002272_abnormal_nervous_system | 0.86566622 |
| 74 | MP0000569_abnormal_digit_pigmentation | 0.86536337 |
| 75 | MP0001905_abnormal_dopamine_level | 0.85548720 |
| 76 | MP0005395_other_phenotype | 0.82820321 |
| 77 | MP0003567_abnormal_fetal_cardiomyocyte | 0.81575167 |
| 78 | MP0008932_abnormal_embryonic_tissue | 0.81247742 |
| 79 | MP0001119_abnormal_female_reproductive | 0.80846485 |
| 80 | MP0000653_abnormal_sex_gland | 0.80343940 |
| 81 | MP0002452_abnormal_antigen_presenting | 0.80131037 |
| 82 | MP0004134_abnormal_chest_morphology | 0.79499598 |
| 83 | MP0006035_abnormal_mitochondrial_morpho | 0.78798567 |
| 84 | MP0003787_abnormal_imprinting | 0.78700577 |
| 85 | MP0001486_abnormal_startle_reflex | 0.78618323 |
| 86 | MP0002234_abnormal_pharynx_morphology | 0.78046588 |
| 87 | MP0001145_abnormal_male_reproductive | 0.77968909 |
| 88 | MP0004133_heterotaxia | 0.75931458 |
| 89 | MP0003938_abnormal_ear_development | 0.75623730 |
| 90 | MP0001819_abnormal_immune_cell | 0.74895374 |
| 91 | MP0002420_abnormal_adaptive_immunity | 0.74185568 |
| 92 | MP0003698_abnormal_male_reproductive | 0.74101496 |
| 93 | MP0001440_abnormal_grooming_behavior | 0.72803415 |
| 94 | MP0004043_abnormal_pH_regulation | 0.72391308 |
| 95 | MP0001485_abnormal_pinna_reflex | 0.72127613 |
| 96 | MP0002733_abnormal_thermal_nociception | 0.70818989 |
| 97 | MP0005387_immune_system_phenotype | 0.70354915 |
| 98 | MP0001790_abnormal_immune_system | 0.70354915 |
| 99 | MP0002138_abnormal_hepatobiliary_system | 0.69509616 |
| 100 | MP0006082_CNS_inflammation | 0.69476989 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.04710728 |
| 2 | Acute encephalopathy (HP:0006846) | 3.85093379 |
| 3 | Progressive macrocephaly (HP:0004481) | 3.69352862 |
| 4 | Lipid accumulation in hepatocytes (HP:0006561) | 3.64328917 |
| 5 | Increased CSF lactate (HP:0002490) | 3.58323421 |
| 6 | Mitochondrial inheritance (HP:0001427) | 3.57428633 |
| 7 | Increased hepatocellular lipid droplets (HP:0006565) | 3.49238148 |
| 8 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.46804986 |
| 9 | Abnormal number of erythroid precursors (HP:0012131) | 3.19032293 |
| 10 | 3-Methylglutaconic aciduria (HP:0003535) | 3.14767533 |
| 11 | Hepatocellular necrosis (HP:0001404) | 3.11297219 |
| 12 | Congenital stationary night blindness (HP:0007642) | 3.10821151 |
| 13 | Renal Fanconi syndrome (HP:0001994) | 3.07315966 |
| 14 | Pancreatic cysts (HP:0001737) | 3.04580548 |
| 15 | Parakeratosis (HP:0001036) | 2.81757278 |
| 16 | Hepatic necrosis (HP:0002605) | 2.79086515 |
| 17 | Progressive microcephaly (HP:0000253) | 2.77589105 |
| 18 | Colon cancer (HP:0003003) | 2.72470331 |
| 19 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.70478534 |
| 20 | Increased serum lactate (HP:0002151) | 2.69667646 |
| 21 | IgG deficiency (HP:0004315) | 2.63074598 |
| 22 | Hyperglycinemia (HP:0002154) | 2.59051998 |
| 23 | Bilateral microphthalmos (HP:0007633) | 2.58456975 |
| 24 | Exertional dyspnea (HP:0002875) | 2.56629773 |
| 25 | Abnormality of the labia minora (HP:0012880) | 2.56565997 |
| 26 | Increased serum pyruvate (HP:0003542) | 2.56320364 |
| 27 | Cerebral edema (HP:0002181) | 2.54976579 |
| 28 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.50566170 |
| 29 | Hyperglycinuria (HP:0003108) | 2.49632510 |
| 30 | Pancreatic fibrosis (HP:0100732) | 2.45755390 |
| 31 | Methylmalonic acidemia (HP:0002912) | 2.41600561 |
| 32 | Type I transferrin isoform profile (HP:0003642) | 2.40775695 |
| 33 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.37025164 |
| 34 | Lactic acidosis (HP:0003128) | 2.33933992 |
| 35 | Optic disc pallor (HP:0000543) | 2.33897191 |
| 36 | Inability to walk (HP:0002540) | 2.30256410 |
| 37 | True hermaphroditism (HP:0010459) | 2.28706000 |
| 38 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.27420917 |
| 39 | Meckel diverticulum (HP:0002245) | 2.27025054 |
| 40 | Pendular nystagmus (HP:0012043) | 2.25733427 |
| 41 | Abnormality of the ileum (HP:0001549) | 2.24578205 |
| 42 | Cerebral hypomyelination (HP:0006808) | 2.22014359 |
| 43 | Progressive inability to walk (HP:0002505) | 2.17382190 |
| 44 | Lethargy (HP:0001254) | 2.17241615 |
| 45 | Abnormality of glycine metabolism (HP:0010895) | 2.16946004 |
| 46 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.16946004 |
| 47 | Hypoplasia of the uterus (HP:0000013) | 2.14919165 |
| 48 | Congenital, generalized hypertrichosis (HP:0004540) | 2.11330856 |
| 49 | Abnormal protein glycosylation (HP:0012346) | 2.10077334 |
| 50 | Abnormal glycosylation (HP:0012345) | 2.10077334 |
| 51 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.10077334 |
| 52 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.10077334 |
| 53 | Abnormality of alanine metabolism (HP:0010916) | 2.09271305 |
| 54 | Hyperalaninemia (HP:0003348) | 2.09271305 |
| 55 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.09271305 |
| 56 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.05598141 |
| 57 | Fibular aplasia (HP:0002990) | 2.04781365 |
| 58 | Amaurosis fugax (HP:0100576) | 2.03407405 |
| 59 | Respiratory failure (HP:0002878) | 2.02309392 |
| 60 | Abolished electroretinogram (ERG) (HP:0000550) | 2.02053098 |
| 61 | Absent thumb (HP:0009777) | 2.01701474 |
| 62 | Hypothermia (HP:0002045) | 2.00599506 |
| 63 | Abnormality of glycolysis (HP:0004366) | 2.00037525 |
| 64 | Abnormality of the pons (HP:0007361) | 1.99021613 |
| 65 | Methylmalonic aciduria (HP:0012120) | 1.97235724 |
| 66 | Hypoplasia of the pons (HP:0012110) | 1.95658324 |
| 67 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.94614638 |
| 68 | Abnormality of the renal cortex (HP:0011035) | 1.94499114 |
| 69 | Hypoproteinemia (HP:0003075) | 1.92538380 |
| 70 | Leukodystrophy (HP:0002415) | 1.91953795 |
| 71 | Abnormality of placental membranes (HP:0011409) | 1.90980870 |
| 72 | Amniotic constriction ring (HP:0009775) | 1.90980870 |
| 73 | Abnormality of macular pigmentation (HP:0008002) | 1.87446642 |
| 74 | Increased intramyocellular lipid droplets (HP:0012240) | 1.87195293 |
| 75 | Duodenal stenosis (HP:0100867) | 1.85400328 |
| 76 | Small intestinal stenosis (HP:0012848) | 1.85400328 |
| 77 | Abnormality of the anterior horn cell (HP:0006802) | 1.84143837 |
| 78 | Degeneration of anterior horn cells (HP:0002398) | 1.84143837 |
| 79 | Exercise intolerance (HP:0003546) | 1.83514279 |
| 80 | Cleft eyelid (HP:0000625) | 1.83375912 |
| 81 | Triphalangeal thumb (HP:0001199) | 1.83111249 |
| 82 | Respiratory difficulties (HP:0002880) | 1.81976881 |
| 83 | Renal cortical cysts (HP:0000803) | 1.81929998 |
| 84 | Nephronophthisis (HP:0000090) | 1.79290058 |
| 85 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.78816323 |
| 86 | Abnormality of the preputium (HP:0100587) | 1.77869979 |
| 87 | Abnormality of renal resorption (HP:0011038) | 1.77807633 |
| 88 | Hypochromic microcytic anemia (HP:0004840) | 1.77728039 |
| 89 | Abnormal drinking behavior (HP:0030082) | 1.77433847 |
| 90 | Polydipsia (HP:0001959) | 1.77433847 |
| 91 | Increased muscle lipid content (HP:0009058) | 1.76929696 |
| 92 | Retrobulbar optic neuritis (HP:0100654) | 1.76548187 |
| 93 | Optic neuritis (HP:0100653) | 1.76548187 |
| 94 | CNS hypomyelination (HP:0003429) | 1.76297356 |
| 95 | Abnormality of serum amino acid levels (HP:0003112) | 1.75813603 |
| 96 | CNS demyelination (HP:0007305) | 1.74989340 |
| 97 | Hyperphosphaturia (HP:0003109) | 1.74700315 |
| 98 | Clubbing of toes (HP:0100760) | 1.73696647 |
| 99 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.73580764 |
| 100 | Anorexia (HP:0002039) | 1.72538776 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 3.84815260 |
| 2 | MAP4K2 | 3.77761813 |
| 3 | MST4 | 3.53308623 |
| 4 | ZAK | 3.47492122 |
| 5 | TXK | 3.05639796 |
| 6 | TLK1 | 2.80792534 |
| 7 | BUB1 | 2.79223551 |
| 8 | PBK | 2.77052938 |
| 9 | NUAK1 | 2.65137322 |
| 10 | FRK | 2.52876670 |
| 11 | TSSK6 | 2.44796523 |
| 12 | SRPK1 | 2.36812552 |
| 13 | EIF2AK1 | 2.31720679 |
| 14 | EIF2AK3 | 2.27494037 |
| 15 | PLK3 | 2.08087091 |
| 16 | NEK1 | 1.94046721 |
| 17 | PINK1 | 1.82027237 |
| 18 | ADRBK2 | 1.80784684 |
| 19 | VRK1 | 1.79323580 |
| 20 | TAOK3 | 1.78061799 |
| 21 | TRIM28 | 1.76701544 |
| 22 | PLK4 | 1.62174116 |
| 23 | BCKDK | 1.45098793 |
| 24 | OXSR1 | 1.45011714 |
| 25 | GRK1 | 1.44463706 |
| 26 | EIF2AK2 | 1.42616952 |
| 27 | TAF1 | 1.32547331 |
| 28 | PHKG2 | 1.31838109 |
| 29 | PHKG1 | 1.31838109 |
| 30 | MAPKAPK3 | 1.30442604 |
| 31 | WNK4 | 1.29870174 |
| 32 | MAP3K4 | 1.24026323 |
| 33 | STK16 | 1.20763922 |
| 34 | MKNK1 | 1.20365586 |
| 35 | NME1 | 1.09153646 |
| 36 | CDC7 | 1.08680294 |
| 37 | MUSK | 1.05309049 |
| 38 | BMPR1B | 1.03515903 |
| 39 | STK39 | 0.99777229 |
| 40 | TTK | 0.99167290 |
| 41 | MKNK2 | 0.97703799 |
| 42 | WNK3 | 0.96344579 |
| 43 | PLK1 | 0.94642294 |
| 44 | PLK2 | 0.94469326 |
| 45 | DAPK1 | 0.92927856 |
| 46 | NEK9 | 0.87073854 |
| 47 | GRK6 | 0.81822060 |
| 48 | FES | 0.80839931 |
| 49 | PDK2 | 0.79738052 |
| 50 | AURKB | 0.71915735 |
| 51 | PASK | 0.69118784 |
| 52 | TESK2 | 0.64611005 |
| 53 | IKBKB | 0.64293829 |
| 54 | PRKCQ | 0.62932890 |
| 55 | STK4 | 0.59871049 |
| 56 | NEK2 | 0.59783683 |
| 57 | DYRK2 | 0.58502423 |
| 58 | ATR | 0.57557249 |
| 59 | CSNK1G1 | 0.53883049 |
| 60 | TNIK | 0.53811313 |
| 61 | GRK5 | 0.52944358 |
| 62 | CDK19 | 0.51884416 |
| 63 | CSNK1G3 | 0.51632010 |
| 64 | CCNB1 | 0.51479655 |
| 65 | IKBKE | 0.50536509 |
| 66 | STK3 | 0.49947710 |
| 67 | INSRR | 0.47736120 |
| 68 | WEE1 | 0.47387169 |
| 69 | PRKCG | 0.47319257 |
| 70 | PRKCI | 0.44464469 |
| 71 | ADRBK1 | 0.44416537 |
| 72 | ERBB3 | 0.44212049 |
| 73 | FGFR2 | 0.43510979 |
| 74 | IRAK4 | 0.42825667 |
| 75 | ALK | 0.42489822 |
| 76 | CHEK2 | 0.39535224 |
| 77 | ITK | 0.38166930 |
| 78 | TGFBR1 | 0.37975327 |
| 79 | STK10 | 0.36351001 |
| 80 | CSNK2A1 | 0.35716786 |
| 81 | DYRK3 | 0.35646670 |
| 82 | CSNK2A2 | 0.35152262 |
| 83 | RPS6KA5 | 0.34653801 |
| 84 | TBK1 | 0.33274738 |
| 85 | KIT | 0.33232541 |
| 86 | TNK2 | 0.33057470 |
| 87 | CSNK1G2 | 0.32244695 |
| 88 | AURKA | 0.30337450 |
| 89 | MAPK13 | 0.29340840 |
| 90 | LCK | 0.28620468 |
| 91 | PRKCE | 0.27252509 |
| 92 | STK38L | 0.26812221 |
| 93 | RPS6KA4 | 0.25896651 |
| 94 | CSNK1A1 | 0.25243755 |
| 95 | PIK3CG | 0.24918806 |
| 96 | ABL1 | 0.24748731 |
| 97 | NME2 | 0.24370673 |
| 98 | LYN | 0.22780895 |
| 99 | TIE1 | 0.22689133 |
| 100 | SYK | 0.22412862 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.26259831 |
| 2 | RNA polymerase_Homo sapiens_hsa03020 | 3.09446574 |
| 3 | Ribosome_Homo sapiens_hsa03010 | 2.84879045 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.73309386 |
| 5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.50589539 |
| 6 | Homologous recombination_Homo sapiens_hsa03440 | 2.43280467 |
| 7 | Parkinsons disease_Homo sapiens_hsa05012 | 2.41853310 |
| 8 | Protein export_Homo sapiens_hsa03060 | 2.33241945 |
| 9 | Asthma_Homo sapiens_hsa05310 | 2.23910850 |
| 10 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.17527374 |
| 11 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.11483321 |
| 12 | RNA degradation_Homo sapiens_hsa03018 | 1.95710351 |
| 13 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.92808617 |
| 14 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.91419278 |
| 15 | Basal transcription factors_Homo sapiens_hsa03022 | 1.89421992 |
| 16 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.84131499 |
| 17 | Base excision repair_Homo sapiens_hsa03410 | 1.80517228 |
| 18 | Allograft rejection_Homo sapiens_hsa05330 | 1.73025355 |
| 19 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.71915366 |
| 20 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.65362062 |
| 21 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.64621049 |
| 22 | Mismatch repair_Homo sapiens_hsa03430 | 1.61731875 |
| 23 | Huntingtons disease_Homo sapiens_hsa05016 | 1.59199185 |
| 24 | RNA transport_Homo sapiens_hsa03013 | 1.58674377 |
| 25 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.55847306 |
| 26 | Alzheimers disease_Homo sapiens_hsa05010 | 1.52371303 |
| 27 | Spliceosome_Homo sapiens_hsa03040 | 1.49755946 |
| 28 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.48899498 |
| 29 | Purine metabolism_Homo sapiens_hsa00230 | 1.47694277 |
| 30 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.46176010 |
| 31 | DNA replication_Homo sapiens_hsa03030 | 1.44924196 |
| 32 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.44195285 |
| 33 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.43445156 |
| 34 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.40515484 |
| 35 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.37695348 |
| 36 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.35901270 |
| 37 | Phototransduction_Homo sapiens_hsa04744 | 1.35294518 |
| 38 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.28686624 |
| 39 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.23653625 |
| 40 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.21499417 |
| 41 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.20675560 |
| 42 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.20151779 |
| 43 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.18821431 |
| 44 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.18519320 |
| 45 | Peroxisome_Homo sapiens_hsa04146 | 1.14581476 |
| 46 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.09544505 |
| 47 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.08769951 |
| 48 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.04938301 |
| 49 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.02529879 |
| 50 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.00848980 |
| 51 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.00011758 |
| 52 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.98875947 |
| 53 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.97929669 |
| 54 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.94123138 |
| 55 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.93914976 |
| 56 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.91503646 |
| 57 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.80865963 |
| 58 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.78972776 |
| 59 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.73684341 |
| 60 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.73576538 |
| 61 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.72509192 |
| 62 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.70292800 |
| 63 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.69558034 |
| 64 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.67309029 |
| 65 | Metabolic pathways_Homo sapiens_hsa01100 | 0.67063526 |
| 66 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.65765377 |
| 67 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.64915648 |
| 68 | Retinol metabolism_Homo sapiens_hsa00830 | 0.63267667 |
| 69 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.63072965 |
| 70 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.60938151 |
| 71 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.58795705 |
| 72 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.57767465 |
| 73 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.52600303 |
| 74 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.52056476 |
| 75 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.47182120 |
| 76 | Olfactory transduction_Homo sapiens_hsa04740 | 0.45202327 |
| 77 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.44400506 |
| 78 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.43729034 |
| 79 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.40539847 |
| 80 | Carbon metabolism_Homo sapiens_hsa01200 | 0.38299982 |
| 81 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.38154603 |
| 82 | Nicotine addiction_Homo sapiens_hsa05033 | 0.38065045 |
| 83 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.37294085 |
| 84 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.35693633 |
| 85 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.35078929 |
| 86 | Morphine addiction_Homo sapiens_hsa05032 | 0.34413521 |
| 87 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.32202688 |
| 88 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.29582012 |
| 89 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.27348502 |
| 90 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.26797479 |
| 91 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.26788942 |
| 92 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.26594003 |
| 93 | Cell cycle_Homo sapiens_hsa04110 | 0.26428836 |
| 94 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.25823511 |
| 95 | ABC transporters_Homo sapiens_hsa02010 | 0.25820999 |
| 96 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.25751058 |
| 97 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.24690340 |
| 98 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.24146902 |
| 99 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.23548060 |
| 100 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.23295034 |

