

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | maturation of 5.8S rRNA (GO:0000460) | 5.27993771 |
| 2 | proteasome assembly (GO:0043248) | 4.90104584 |
| 3 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.67291909 |
| 4 | DNA deamination (GO:0045006) | 4.61271632 |
| 5 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.31802986 |
| 6 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.96389410 |
| 7 | ribosome assembly (GO:0042255) | 3.93762133 |
| 8 | negative regulation of telomere maintenance (GO:0032205) | 3.89473590 |
| 9 | base-excision repair, AP site formation (GO:0006285) | 3.85033240 |
| 10 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.83482125 |
| 11 | chaperone-mediated protein transport (GO:0072321) | 3.78279299 |
| 12 | rRNA modification (GO:0000154) | 3.73977117 |
| 13 | peptidyl-histidine modification (GO:0018202) | 3.73122094 |
| 14 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.60826707 |
| 15 | regulation of immunoglobulin secretion (GO:0051023) | 3.59764111 |
| 16 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.55548787 |
| 17 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.50072778 |
| 18 | negative regulation of ligase activity (GO:0051352) | 3.50072778 |
| 19 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.49094756 |
| 20 | cullin deneddylation (GO:0010388) | 3.48311401 |
| 21 | protein neddylation (GO:0045116) | 3.48159294 |
| 22 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.48149817 |
| 23 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.48149817 |
| 24 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.46195508 |
| 25 | ATP synthesis coupled proton transport (GO:0015986) | 3.45830951 |
| 26 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.45830951 |
| 27 | protein deneddylation (GO:0000338) | 3.44115738 |
| 28 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.44064170 |
| 29 | purine nucleobase biosynthetic process (GO:0009113) | 3.43833982 |
| 30 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.43684069 |
| 31 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.42277259 |
| 32 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.41021030 |
| 33 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.41021030 |
| 34 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.41021030 |
| 35 | nucleobase biosynthetic process (GO:0046112) | 3.35418265 |
| 36 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.33922461 |
| 37 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.33922461 |
| 38 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.30988114 |
| 39 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.30988114 |
| 40 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.26788354 |
| 41 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.26721001 |
| 42 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.26721001 |
| 43 | histone mRNA metabolic process (GO:0008334) | 3.25664358 |
| 44 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.22579497 |
| 45 | spliceosomal snRNP assembly (GO:0000387) | 3.21981262 |
| 46 | cellular response to ATP (GO:0071318) | 3.18524672 |
| 47 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.17938894 |
| 48 | IMP biosynthetic process (GO:0006188) | 3.10364954 |
| 49 | DNA replication checkpoint (GO:0000076) | 3.09551747 |
| 50 | rRNA processing (GO:0006364) | 3.04384994 |
| 51 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.01519959 |
| 52 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.01519959 |
| 53 | NADH dehydrogenase complex assembly (GO:0010257) | 3.01519959 |
| 54 | termination of RNA polymerase I transcription (GO:0006363) | 3.00876457 |
| 55 | rRNA methylation (GO:0031167) | 3.00868112 |
| 56 | maturation of SSU-rRNA (GO:0030490) | 3.00564290 |
| 57 | protein complex biogenesis (GO:0070271) | 3.00008678 |
| 58 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.99812839 |
| 59 | negative regulation of B cell apoptotic process (GO:0002903) | 2.98920180 |
| 60 | regulation of helicase activity (GO:0051095) | 2.98646468 |
| 61 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.97556824 |
| 62 | rRNA metabolic process (GO:0016072) | 2.96420113 |
| 63 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.93569308 |
| 64 | pseudouridine synthesis (GO:0001522) | 2.91049343 |
| 65 | pteridine-containing compound biosynthetic process (GO:0042559) | 2.87948004 |
| 66 | CENP-A containing nucleosome assembly (GO:0034080) | 2.87462327 |
| 67 | tRNA aminoacylation for protein translation (GO:0006418) | 2.87345649 |
| 68 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.85889181 |
| 69 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 2.85488289 |
| 70 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.84018261 |
| 71 | positive regulation of ligase activity (GO:0051351) | 2.83941947 |
| 72 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.83076774 |
| 73 | chromatin remodeling at centromere (GO:0031055) | 2.81768229 |
| 74 | ncRNA catabolic process (GO:0034661) | 2.80816256 |
| 75 | purine nucleotide salvage (GO:0032261) | 2.80813262 |
| 76 | lactate metabolic process (GO:0006089) | 2.80395210 |
| 77 | positive regulation of isotype switching (GO:0045830) | 2.78434367 |
| 78 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.76797502 |
| 79 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.76408817 |
| 80 | ribosome biogenesis (GO:0042254) | 2.74497882 |
| 81 | tRNA aminoacylation (GO:0043039) | 2.72364533 |
| 82 | amino acid activation (GO:0043038) | 2.72364533 |
| 83 | regulation of cellular amine metabolic process (GO:0033238) | 2.71872323 |
| 84 | ribosomal small subunit assembly (GO:0000028) | 2.71787291 |
| 85 | positive regulation of cell cycle arrest (GO:0071158) | 2.71563260 |
| 86 | GTP biosynthetic process (GO:0006183) | 2.69613575 |
| 87 | DNA double-strand break processing (GO:0000729) | 2.68065338 |
| 88 | negative regulation of T cell differentiation in thymus (GO:0033085) | 2.67545185 |
| 89 | resolution of meiotic recombination intermediates (GO:0000712) | 2.67451337 |
| 90 | tRNA processing (GO:0008033) | 2.66668814 |
| 91 | attachment of spindle microtubules to kinetochore (GO:0008608) | 2.66074118 |
| 92 | tryptophan metabolic process (GO:0006568) | 2.64711770 |
| 93 | negative regulation of DNA recombination (GO:0045910) | 2.64139144 |
| 94 | regulation of ligase activity (GO:0051340) | 2.64004789 |
| 95 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.63792141 |
| 96 | positive regulation of DNA recombination (GO:0045911) | 2.63323155 |
| 97 | cellular ketone body metabolic process (GO:0046950) | 2.61769081 |
| 98 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.61628897 |
| 99 | protein K63-linked deubiquitination (GO:0070536) | 2.61275311 |
| 100 | tRNA metabolic process (GO:0006399) | 2.60646218 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.89568174 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.70815110 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.87915821 |
| 4 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.72994001 |
| 5 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.26736197 |
| 6 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.21339456 |
| 7 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.16566870 |
| 8 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.13473120 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.88096465 |
| 10 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.84609103 |
| 11 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.83379922 |
| 12 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.73722738 |
| 13 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.62376196 |
| 14 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.59150740 |
| 15 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.57641392 |
| 16 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.55592442 |
| 17 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.51958376 |
| 18 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.49744267 |
| 19 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.18692232 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.18250208 |
| 21 | VDR_22108803_ChIP-Seq_LS180_Human | 2.09865750 |
| 22 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.99295374 |
| 23 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.97467279 |
| 24 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.94017299 |
| 25 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.90692756 |
| 26 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.90683525 |
| 27 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.90234388 |
| 28 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.85683027 |
| 29 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.85032123 |
| 30 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.81302153 |
| 31 | EWS_26573619_Chip-Seq_HEK293_Human | 1.78402253 |
| 32 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.69289214 |
| 33 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.65402202 |
| 34 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.65076204 |
| 35 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.64522160 |
| 36 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.63550129 |
| 37 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.61845494 |
| 38 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.53627143 |
| 39 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.52933920 |
| 40 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.51308769 |
| 41 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.48279718 |
| 42 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.47870913 |
| 43 | FUS_26573619_Chip-Seq_HEK293_Human | 1.43892423 |
| 44 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.42808796 |
| 45 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.40405658 |
| 46 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.40374102 |
| 47 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.40130371 |
| 48 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.39382040 |
| 49 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.36322866 |
| 50 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.36276224 |
| 51 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.36055622 |
| 52 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.35259297 |
| 53 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.29760118 |
| 54 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.29533844 |
| 55 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.29435958 |
| 56 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.27527234 |
| 57 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.27139129 |
| 58 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.25948881 |
| 59 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.24712925 |
| 60 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.23541033 |
| 61 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.22669748 |
| 62 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.19910294 |
| 63 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.19628340 |
| 64 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.19396684 |
| 65 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.18806465 |
| 66 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.18566584 |
| 67 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.18498581 |
| 68 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.18498581 |
| 69 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.17928725 |
| 70 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.17532242 |
| 71 | P300_19829295_ChIP-Seq_ESCs_Human | 1.13356789 |
| 72 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.10451910 |
| 73 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.09666953 |
| 74 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.08000286 |
| 75 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.07678825 |
| 76 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.07575817 |
| 77 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.07575817 |
| 78 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.07031085 |
| 79 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.06036744 |
| 80 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.05266950 |
| 81 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.04559673 |
| 82 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.03197128 |
| 83 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.02517827 |
| 84 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.00518057 |
| 85 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.97271741 |
| 86 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.96938063 |
| 87 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.95548388 |
| 88 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.95413419 |
| 89 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.93664122 |
| 90 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.93567591 |
| 91 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.92024278 |
| 92 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.90162616 |
| 93 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.88513333 |
| 94 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.88327348 |
| 95 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.88217150 |
| 96 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.87842640 |
| 97 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.87842640 |
| 98 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.86256561 |
| 99 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.85108835 |
| 100 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.82274003 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003693_abnormal_embryo_hatching | 3.86668644 |
| 2 | MP0002102_abnormal_ear_morphology | 3.31087290 |
| 3 | MP0008058_abnormal_DNA_repair | 3.18254939 |
| 4 | MP0008877_abnormal_DNA_methylation | 2.70284455 |
| 5 | MP0008875_abnormal_xenobiotic_pharmacok | 2.63774561 |
| 6 | MP0003718_maternal_effect | 2.56845136 |
| 7 | MP0003890_abnormal_embryonic-extraembry | 2.48431908 |
| 8 | MP0004957_abnormal_blastocyst_morpholog | 2.43246529 |
| 9 | MP0003195_calcinosis | 2.38366152 |
| 10 | MP0009697_abnormal_copulation | 2.38110626 |
| 11 | MP0003806_abnormal_nucleotide_metabolis | 2.34673140 |
| 12 | MP0008057_abnormal_DNA_replication | 2.31580793 |
| 13 | MP0003786_premature_aging | 2.21611403 |
| 14 | MP0008007_abnormal_cellular_replicative | 2.18611893 |
| 15 | MP0006072_abnormal_retinal_apoptosis | 2.09831979 |
| 16 | MP0003567_abnormal_fetal_cardiomyocyte | 2.08143223 |
| 17 | MP0001984_abnormal_olfaction | 2.01103576 |
| 18 | MP0002736_abnormal_nociception_after | 1.92824107 |
| 19 | MP0001188_hyperpigmentation | 1.88762281 |
| 20 | MP0004147_increased_porphyrin_level | 1.82966854 |
| 21 | MP0006292_abnormal_olfactory_placode | 1.79709995 |
| 22 | MP0001529_abnormal_vocalization | 1.73027950 |
| 23 | MP0008872_abnormal_physiological_respon | 1.72970627 |
| 24 | MP0005408_hypopigmentation | 1.72354600 |
| 25 | MP0003111_abnormal_nucleus_morphology | 1.71840988 |
| 26 | MP0000372_irregular_coat_pigmentation | 1.70761976 |
| 27 | MP0008995_early_reproductive_senescence | 1.69057571 |
| 28 | MP0009333_abnormal_splenocyte_physiolog | 1.68115881 |
| 29 | MP0002938_white_spotting | 1.65161174 |
| 30 | MP0003787_abnormal_imprinting | 1.62911102 |
| 31 | MP0003880_abnormal_central_pattern | 1.61652303 |
| 32 | MP0001986_abnormal_taste_sensitivity | 1.58764344 |
| 33 | MP0001835_abnormal_antigen_presentation | 1.54355193 |
| 34 | MP0005084_abnormal_gallbladder_morpholo | 1.54112008 |
| 35 | MP0005423_abnormal_somatic_nervous | 1.53631565 |
| 36 | MP0001873_stomach_inflammation | 1.51526773 |
| 37 | MP0010094_abnormal_chromosome_stability | 1.50467502 |
| 38 | MP0002277_abnormal_respiratory_mucosa | 1.50277369 |
| 39 | MP0003077_abnormal_cell_cycle | 1.44353745 |
| 40 | MP0005671_abnormal_response_to | 1.41643821 |
| 41 | MP0002751_abnormal_autonomic_nervous | 1.40306298 |
| 42 | MP0001790_abnormal_immune_system | 1.39554664 |
| 43 | MP0005387_immune_system_phenotype | 1.39554664 |
| 44 | MP0010386_abnormal_urinary_bladder | 1.37765222 |
| 45 | MP0003119_abnormal_digestive_system | 1.36988155 |
| 46 | MP0004142_abnormal_muscle_tone | 1.35656034 |
| 47 | MP0003186_abnormal_redox_activity | 1.33652031 |
| 48 | MP0006035_abnormal_mitochondrial_morpho | 1.21029454 |
| 49 | MP0005253_abnormal_eye_physiology | 1.18971950 |
| 50 | MP0001968_abnormal_touch/_nociception | 1.17940368 |
| 51 | MP0006276_abnormal_autonomic_nervous | 1.16894379 |
| 52 | MP0003011_delayed_dark_adaptation | 1.14293372 |
| 53 | MP0005377_hearing/vestibular/ear_phenot | 1.11151893 |
| 54 | MP0003878_abnormal_ear_physiology | 1.11151893 |
| 55 | MP0003300_gastrointestinal_ulcer | 1.11140614 |
| 56 | MP0005395_other_phenotype | 1.08062010 |
| 57 | MP0001905_abnormal_dopamine_level | 1.06057078 |
| 58 | MP0005551_abnormal_eye_electrophysiolog | 1.05543704 |
| 59 | MP0002006_tumorigenesis | 1.04695583 |
| 60 | MP0002837_dystrophic_cardiac_calcinosis | 1.03131592 |
| 61 | MP0003283_abnormal_digestive_organ | 1.02417687 |
| 62 | MP0003646_muscle_fatigue | 1.01488595 |
| 63 | MP0004133_heterotaxia | 1.01472021 |
| 64 | MP0001764_abnormal_homeostasis | 1.01288038 |
| 65 | MP0002735_abnormal_chemical_nociception | 1.00455757 |
| 66 | MP0002638_abnormal_pupillary_reflex | 1.00222794 |
| 67 | MP0008789_abnormal_olfactory_epithelium | 0.94966939 |
| 68 | MP0005389_reproductive_system_phenotype | 0.92638652 |
| 69 | MP0005646_abnormal_pituitary_gland | 0.92521183 |
| 70 | MP0008932_abnormal_embryonic_tissue | 0.91329575 |
| 71 | MP0002234_abnormal_pharynx_morphology | 0.89153318 |
| 72 | MP0008873_increased_physiological_sensi | 0.88160364 |
| 73 | MP0002160_abnormal_reproductive_system | 0.87383688 |
| 74 | MP0001919_abnormal_reproductive_system | 0.85325846 |
| 75 | MP0005075_abnormal_melanosome_morpholog | 0.82494373 |
| 76 | MP0002148_abnormal_hypersensitivity_rea | 0.81529400 |
| 77 | MP0003137_abnormal_impulse_conducting | 0.80836839 |
| 78 | MP0005645_abnormal_hypothalamus_physiol | 0.80078187 |
| 79 | MP0002019_abnormal_tumor_incidence | 0.79981395 |
| 80 | MP0005636_abnormal_mineral_homeostasis | 0.79710320 |
| 81 | MP0004215_abnormal_myocardial_fiber | 0.79310504 |
| 82 | MP0005187_abnormal_penis_morphology | 0.78718929 |
| 83 | MP0003045_fibrosis | 0.77939055 |
| 84 | MP0002138_abnormal_hepatobiliary_system | 0.77752529 |
| 85 | MP0004742_abnormal_vestibular_system | 0.77273416 |
| 86 | MP0009785_altered_susceptibility_to | 0.75962948 |
| 87 | MP0000465_gastrointestinal_hemorrhage | 0.71286967 |
| 88 | MP0006036_abnormal_mitochondrial_physio | 0.71038272 |
| 89 | MP0001293_anophthalmia | 0.70877433 |
| 90 | MP0002693_abnormal_pancreas_physiology | 0.69843998 |
| 91 | MP0000358_abnormal_cell_content/ | 0.69014031 |
| 92 | MP0002734_abnormal_mechanical_nocicepti | 0.68865939 |
| 93 | MP0002210_abnormal_sex_determination | 0.68840768 |
| 94 | MP0001853_heart_inflammation | 0.68352096 |
| 95 | MP0009379_abnormal_foot_pigmentation | 0.68138523 |
| 96 | MP0000647_abnormal_sebaceous_gland | 0.66811497 |
| 97 | MP0001929_abnormal_gametogenesis | 0.66694820 |
| 98 | MP0001119_abnormal_female_reproductive | 0.64732176 |
| 99 | MP0005085_abnormal_gallbladder_physiolo | 0.63689725 |
| 100 | MP0003221_abnormal_cardiomyocyte_apopto | 0.63097887 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Methylmalonic acidemia (HP:0002912) | 4.66380756 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 4.04944479 |
| 3 | Acute encephalopathy (HP:0006846) | 3.80091145 |
| 4 | Hypoproteinemia (HP:0003075) | 3.78744065 |
| 5 | Methylmalonic aciduria (HP:0012120) | 3.68814209 |
| 6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.43977821 |
| 7 | Progressive macrocephaly (HP:0004481) | 3.43079639 |
| 8 | Abnormality of the ileum (HP:0001549) | 3.39452573 |
| 9 | Meckel diverticulum (HP:0002245) | 3.37393578 |
| 10 | Reduced antithrombin III activity (HP:0001976) | 3.36342533 |
| 11 | Colon cancer (HP:0003003) | 3.27454958 |
| 12 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 3.21530062 |
| 13 | Carpal bone hypoplasia (HP:0001498) | 3.21401146 |
| 14 | Hypoplasia of the pons (HP:0012110) | 3.19971390 |
| 15 | Hyperglycinemia (HP:0002154) | 3.17981654 |
| 16 | Increased hepatocellular lipid droplets (HP:0006565) | 3.10618188 |
| 17 | Increased CSF lactate (HP:0002490) | 3.08575411 |
| 18 | Type I transferrin isoform profile (HP:0003642) | 3.02679614 |
| 19 | Mitochondrial inheritance (HP:0001427) | 3.00079341 |
| 20 | Abnormality of the pons (HP:0007361) | 2.94273416 |
| 21 | Pancytopenia (HP:0001876) | 2.90437227 |
| 22 | Lipid accumulation in hepatocytes (HP:0006561) | 2.82464038 |
| 23 | Abnormality of the preputium (HP:0100587) | 2.82414595 |
| 24 | Pancreatic cysts (HP:0001737) | 2.79841697 |
| 25 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.73963462 |
| 26 | Small intestinal stenosis (HP:0012848) | 2.73564799 |
| 27 | Duodenal stenosis (HP:0100867) | 2.73564799 |
| 28 | Stomatitis (HP:0010280) | 2.71945028 |
| 29 | Abnormality of DNA repair (HP:0003254) | 2.67180838 |
| 30 | Abnormality of the labia minora (HP:0012880) | 2.62551970 |
| 31 | Cerebral edema (HP:0002181) | 2.60963460 |
| 32 | IgG deficiency (HP:0004315) | 2.60043910 |
| 33 | Absent thumb (HP:0009777) | 2.58490684 |
| 34 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.58375264 |
| 35 | Abnormality of vitamin B metabolism (HP:0004340) | 2.54727500 |
| 36 | Abnormality of methionine metabolism (HP:0010901) | 2.52219993 |
| 37 | 3-Methylglutaconic aciduria (HP:0003535) | 2.51485014 |
| 38 | Spinal muscular atrophy (HP:0007269) | 2.50881065 |
| 39 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 2.48682435 |
| 40 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.45295902 |
| 41 | Abnormality of alanine metabolism (HP:0010916) | 2.45295902 |
| 42 | Hyperalaninemia (HP:0003348) | 2.45295902 |
| 43 | Abnormality of serum amino acid levels (HP:0003112) | 2.44636435 |
| 44 | Dicarboxylic aciduria (HP:0003215) | 2.44461373 |
| 45 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.44461373 |
| 46 | Abnormality of chromosome stability (HP:0003220) | 2.40477603 |
| 47 | Supernumerary spleens (HP:0009799) | 2.40211257 |
| 48 | Optic disc pallor (HP:0000543) | 2.39381124 |
| 49 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.35467064 |
| 50 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.35467064 |
| 51 | Abnormal protein glycosylation (HP:0012346) | 2.35467064 |
| 52 | Abnormal glycosylation (HP:0012345) | 2.35467064 |
| 53 | Abnormality of the duodenum (HP:0002246) | 2.34281888 |
| 54 | Horseshoe kidney (HP:0000085) | 2.33695438 |
| 55 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.33000126 |
| 56 | Abnormality of glycine metabolism (HP:0010895) | 2.33000126 |
| 57 | Abnormal lung lobation (HP:0002101) | 2.32591708 |
| 58 | Abnormality of the carotid arteries (HP:0005344) | 2.31478805 |
| 59 | Pancreatic fibrosis (HP:0100732) | 2.23793970 |
| 60 | Hepatic necrosis (HP:0002605) | 2.20078820 |
| 61 | Clubbing of toes (HP:0100760) | 2.19932831 |
| 62 | Increased serum lactate (HP:0002151) | 2.18947940 |
| 63 | Increased intramyocellular lipid droplets (HP:0012240) | 2.18129754 |
| 64 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.17429058 |
| 65 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.15522921 |
| 66 | Exercise intolerance (HP:0003546) | 2.13725777 |
| 67 | Lactic acidosis (HP:0003128) | 2.11186672 |
| 68 | Lethargy (HP:0001254) | 2.11177043 |
| 69 | Bilateral microphthalmos (HP:0007633) | 2.10691416 |
| 70 | Hepatocellular necrosis (HP:0001404) | 2.07816631 |
| 71 | True hermaphroditism (HP:0010459) | 2.06364413 |
| 72 | Reticulocytopenia (HP:0001896) | 2.05829372 |
| 73 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.05415277 |
| 74 | Type 2 muscle fiber atrophy (HP:0003554) | 2.04157221 |
| 75 | Abnormality of the anterior horn cell (HP:0006802) | 2.02965676 |
| 76 | Degeneration of anterior horn cells (HP:0002398) | 2.02965676 |
| 77 | Leukodystrophy (HP:0002415) | 2.02098257 |
| 78 | Exertional dyspnea (HP:0002875) | 2.01418134 |
| 79 | Myelodysplasia (HP:0002863) | 2.00651244 |
| 80 | Increased IgM level (HP:0003496) | 1.98195704 |
| 81 | Hypothermia (HP:0002045) | 1.95115860 |
| 82 | Progressive inability to walk (HP:0002505) | 1.93677494 |
| 83 | Triphalangeal thumb (HP:0001199) | 1.91658206 |
| 84 | Hyperglycinuria (HP:0003108) | 1.90803054 |
| 85 | Chromsome breakage (HP:0040012) | 1.90406987 |
| 86 | Hypoglycemic coma (HP:0001325) | 1.87741445 |
| 87 | Homocystinuria (HP:0002156) | 1.82620046 |
| 88 | Abnormality of homocysteine metabolism (HP:0010919) | 1.82620046 |
| 89 | Multiple enchondromatosis (HP:0005701) | 1.82108169 |
| 90 | Generalized aminoaciduria (HP:0002909) | 1.81349960 |
| 91 | Renal Fanconi syndrome (HP:0001994) | 1.80106600 |
| 92 | Congenital stationary night blindness (HP:0007642) | 1.79798869 |
| 93 | Sloping forehead (HP:0000340) | 1.79090201 |
| 94 | Aplastic anemia (HP:0001915) | 1.78176993 |
| 95 | Oligohydramnios (HP:0001562) | 1.77859021 |
| 96 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.77507284 |
| 97 | Muscle fiber atrophy (HP:0100295) | 1.77270991 |
| 98 | Renal cortical cysts (HP:0000803) | 1.77040315 |
| 99 | Respiratory failure (HP:0002878) | 1.77022239 |
| 100 | Neoplasm of the adrenal gland (HP:0100631) | 1.75616046 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BUB1 | 4.97681727 |
| 2 | TSSK6 | 4.61690549 |
| 3 | ZAK | 4.33673371 |
| 4 | VRK2 | 3.47713869 |
| 5 | TLK1 | 2.58185765 |
| 6 | PBK | 2.44802993 |
| 7 | TRIM28 | 2.39588141 |
| 8 | EIF2AK3 | 2.36293541 |
| 9 | VRK1 | 2.29954221 |
| 10 | SRPK1 | 2.23905599 |
| 11 | NME1 | 2.08318069 |
| 12 | MST4 | 2.03262423 |
| 13 | PASK | 1.99803156 |
| 14 | MKNK1 | 1.96130803 |
| 15 | PLK3 | 1.84868032 |
| 16 | CDC7 | 1.83812858 |
| 17 | TXK | 1.83113684 |
| 18 | KDR | 1.80605924 |
| 19 | WNK3 | 1.70258959 |
| 20 | MKNK2 | 1.66913752 |
| 21 | GRK1 | 1.62196235 |
| 22 | ADRBK2 | 1.53798882 |
| 23 | TTK | 1.47616938 |
| 24 | AKT3 | 1.39342650 |
| 25 | MAP4K2 | 1.37787038 |
| 26 | MAP3K10 | 1.37588921 |
| 27 | TNIK | 1.37502937 |
| 28 | BCKDK | 1.35460956 |
| 29 | PINK1 | 1.27878815 |
| 30 | FRK | 1.20726355 |
| 31 | TAF1 | 1.19183902 |
| 32 | ITK | 1.13824727 |
| 33 | RPS6KA5 | 1.13275418 |
| 34 | EIF2AK1 | 1.12327125 |
| 35 | ATR | 1.10631767 |
| 36 | JAK3 | 1.10527209 |
| 37 | NUAK1 | 1.06611142 |
| 38 | WEE1 | 1.05843259 |
| 39 | DYRK2 | 1.04674685 |
| 40 | STK4 | 1.00357885 |
| 41 | PLK4 | 0.94064671 |
| 42 | ACVR1B | 0.93386785 |
| 43 | CAMKK2 | 0.93255441 |
| 44 | PLK1 | 0.92929542 |
| 45 | CSNK1G3 | 0.87794902 |
| 46 | SIK3 | 0.86374847 |
| 47 | BCR | 0.82960863 |
| 48 | STK16 | 0.82328902 |
| 49 | BMPR1B | 0.81211264 |
| 50 | PLK2 | 0.80305194 |
| 51 | CSNK1A1L | 0.77619372 |
| 52 | TIE1 | 0.77192846 |
| 53 | CSNK1G1 | 0.76793887 |
| 54 | IKBKE | 0.76524365 |
| 55 | DYRK3 | 0.75146195 |
| 56 | CHEK2 | 0.72156932 |
| 57 | TGFBR1 | 0.67850643 |
| 58 | PNCK | 0.67512031 |
| 59 | CSNK1G2 | 0.67055817 |
| 60 | IKBKB | 0.66224222 |
| 61 | NEK1 | 0.65988617 |
| 62 | ERBB3 | 0.64121345 |
| 63 | DAPK2 | 0.62614360 |
| 64 | OXSR1 | 0.62185567 |
| 65 | INSRR | 0.62001954 |
| 66 | MAP2K7 | 0.59995152 |
| 67 | AURKB | 0.58934556 |
| 68 | TEC | 0.53848854 |
| 69 | PAK4 | 0.52508694 |
| 70 | MAP4K1 | 0.51410274 |
| 71 | NEK9 | 0.50754333 |
| 72 | ALK | 0.50680763 |
| 73 | DAPK1 | 0.47860314 |
| 74 | PDK2 | 0.47279523 |
| 75 | ATM | 0.46626697 |
| 76 | CSNK2A2 | 0.44966129 |
| 77 | KIT | 0.43728792 |
| 78 | PRKCE | 0.43091310 |
| 79 | CSNK1A1 | 0.41672364 |
| 80 | BRSK2 | 0.40919793 |
| 81 | CSNK2A1 | 0.39848669 |
| 82 | AURKA | 0.39686984 |
| 83 | WNK4 | 0.39436195 |
| 84 | FGFR1 | 0.37376003 |
| 85 | PRKCG | 0.34012772 |
| 86 | CSNK1E | 0.33936752 |
| 87 | CLK1 | 0.33818984 |
| 88 | LYN | 0.33757558 |
| 89 | BRAF | 0.32827367 |
| 90 | IGF1R | 0.29867515 |
| 91 | PIK3CG | 0.28408387 |
| 92 | DAPK3 | 0.25834659 |
| 93 | ERBB2 | 0.25819356 |
| 94 | CHEK1 | 0.23896099 |
| 95 | PRKCA | 0.23831109 |
| 96 | PRKDC | 0.22392804 |
| 97 | PRKACA | 0.20519871 |
| 98 | MAP3K12 | 0.20332989 |
| 99 | STK39 | 0.19283101 |
| 100 | PIM1 | 0.18901883 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.64674712 |
| 2 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.42584254 |
| 3 | Mismatch repair_Homo sapiens_hsa03430 | 2.63980037 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.62987124 |
| 5 | Basal transcription factors_Homo sapiens_hsa03022 | 2.36605150 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.30407057 |
| 7 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.29714995 |
| 8 | Homologous recombination_Homo sapiens_hsa03440 | 2.16974978 |
| 9 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.11503268 |
| 10 | Parkinsons disease_Homo sapiens_hsa05012 | 2.08184214 |
| 11 | Ribosome_Homo sapiens_hsa03010 | 2.05716642 |
| 12 | RNA polymerase_Homo sapiens_hsa03020 | 2.04265333 |
| 13 | DNA replication_Homo sapiens_hsa03030 | 2.03756102 |
| 14 | Base excision repair_Homo sapiens_hsa03410 | 1.99141399 |
| 15 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.96125230 |
| 16 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.94457955 |
| 17 | RNA transport_Homo sapiens_hsa03013 | 1.91818226 |
| 18 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.89309101 |
| 19 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.81083501 |
| 20 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.68553529 |
| 21 | RNA degradation_Homo sapiens_hsa03018 | 1.68490779 |
| 22 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.60470238 |
| 23 | Spliceosome_Homo sapiens_hsa03040 | 1.58816291 |
| 24 | Asthma_Homo sapiens_hsa05310 | 1.44046419 |
| 25 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.40278220 |
| 26 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.40273969 |
| 27 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.39793179 |
| 28 | Allograft rejection_Homo sapiens_hsa05330 | 1.36531318 |
| 29 | Huntingtons disease_Homo sapiens_hsa05016 | 1.36212383 |
| 30 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.34300417 |
| 31 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.33990217 |
| 32 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.29173099 |
| 33 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.26533618 |
| 34 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.23695888 |
| 35 | Purine metabolism_Homo sapiens_hsa00230 | 1.22306078 |
| 36 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.19805789 |
| 37 | Peroxisome_Homo sapiens_hsa04146 | 1.19549424 |
| 38 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.19339919 |
| 39 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.18934771 |
| 40 | Alzheimers disease_Homo sapiens_hsa05010 | 1.18580896 |
| 41 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.17027256 |
| 42 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.13317132 |
| 43 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.07179050 |
| 44 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.06351300 |
| 45 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.06292029 |
| 46 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.05397095 |
| 47 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.01565284 |
| 48 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.00475238 |
| 49 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.00366409 |
| 50 | Phototransduction_Homo sapiens_hsa04744 | 0.98603098 |
| 51 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.94450047 |
| 52 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.94096371 |
| 53 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.92629637 |
| 54 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.89990645 |
| 55 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.86731622 |
| 56 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.86597155 |
| 57 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.86497290 |
| 58 | Carbon metabolism_Homo sapiens_hsa01200 | 0.85327125 |
| 59 | Alcoholism_Homo sapiens_hsa05034 | 0.84978662 |
| 60 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.84123801 |
| 61 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.83659870 |
| 62 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.83243686 |
| 63 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.79991596 |
| 64 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.78223524 |
| 65 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.76551343 |
| 66 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.72895577 |
| 67 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.72654101 |
| 68 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.72029896 |
| 69 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.65488664 |
| 70 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.65198380 |
| 71 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.64336395 |
| 72 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.62416921 |
| 73 | Metabolic pathways_Homo sapiens_hsa01100 | 0.61060416 |
| 74 | Histidine metabolism_Homo sapiens_hsa00340 | 0.59337406 |
| 75 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.56933185 |
| 76 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.56511303 |
| 77 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.54546705 |
| 78 | Cell cycle_Homo sapiens_hsa04110 | 0.54441427 |
| 79 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.54352525 |
| 80 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.53638977 |
| 81 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.53554209 |
| 82 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.53371571 |
| 83 | ABC transporters_Homo sapiens_hsa02010 | 0.48123706 |
| 84 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.46833947 |
| 85 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.46699873 |
| 86 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.46498722 |
| 87 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.45377041 |
| 88 | Measles_Homo sapiens_hsa05162 | 0.43786616 |
| 89 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.43659204 |
| 90 | Retinol metabolism_Homo sapiens_hsa00830 | 0.41772832 |
| 91 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.41547228 |
| 92 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.41359483 |
| 93 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.41270931 |
| 94 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.35919392 |
| 95 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.35326181 |
| 96 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.34922800 |
| 97 | Olfactory transduction_Homo sapiens_hsa04740 | 0.31259942 |
| 98 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.30865191 |
| 99 | Taste transduction_Homo sapiens_hsa04742 | 0.28436144 |
| 100 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.28241696 |

