

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | otic vesicle formation (GO:0030916) | 9.25142355 |
| 2 | limb bud formation (GO:0060174) | 6.30503145 |
| 3 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.73146462 |
| 4 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 5.25732280 |
| 5 | lateral sprouting from an epithelium (GO:0060601) | 5.12485811 |
| 6 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.10098285 |
| 7 | lens fiber cell development (GO:0070307) | 5.03076508 |
| 8 | digestive tract morphogenesis (GO:0048546) | 4.78508977 |
| 9 | ATP synthesis coupled proton transport (GO:0015986) | 4.72773399 |
| 10 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.72773399 |
| 11 | protein neddylation (GO:0045116) | 4.57360512 |
| 12 | proteasome assembly (GO:0043248) | 4.52631775 |
| 13 | melanin biosynthetic process (GO:0042438) | 4.48570608 |
| 14 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 4.39391659 |
| 15 | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:006052 | 4.34489020 |
| 16 | maturation of SSU-rRNA (GO:0030490) | 4.26995353 |
| 17 | ribosomal small subunit assembly (GO:0000028) | 4.24843372 |
| 18 | lung-associated mesenchyme development (GO:0060484) | 4.08946201 |
| 19 | melanin metabolic process (GO:0006582) | 4.06202688 |
| 20 | secondary metabolite biosynthetic process (GO:0044550) | 4.06042385 |
| 21 | presynaptic membrane assembly (GO:0097105) | 3.98092271 |
| 22 | retinal rod cell development (GO:0046548) | 3.92862613 |
| 23 | notochord development (GO:0030903) | 3.89465300 |
| 24 | ribosomal large subunit biogenesis (GO:0042273) | 3.80201326 |
| 25 | negative regulation of membrane potential (GO:0045837) | 3.77035451 |
| 26 | regulation of branching involved in prostate gland morphogenesis (GO:0060687) | 3.73342537 |
| 27 | protein deneddylation (GO:0000338) | 3.61352357 |
| 28 | cullin deneddylation (GO:0010388) | 3.61166502 |
| 29 | organ growth (GO:0035265) | 3.60647471 |
| 30 | chaperone-mediated protein transport (GO:0072321) | 3.58336616 |
| 31 | regulation of regulatory T cell differentiation (GO:0045589) | 3.51675081 |
| 32 | prostate gland growth (GO:0060736) | 3.46928948 |
| 33 | respiratory electron transport chain (GO:0022904) | 3.43719895 |
| 34 | positive regulation of RNA splicing (GO:0033120) | 3.43327098 |
| 35 | electron transport chain (GO:0022900) | 3.40825663 |
| 36 | nephron tubule formation (GO:0072079) | 3.39904830 |
| 37 | lung lobe morphogenesis (GO:0060463) | 3.37085932 |
| 38 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.36381375 |
| 39 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.32823229 |
| 40 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.31765188 |
| 41 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.31682558 |
| 42 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.31629616 |
| 43 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.26084590 |
| 44 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.26084590 |
| 45 | viral transcription (GO:0019083) | 3.24509978 |
| 46 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.24284268 |
| 47 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.24284268 |
| 48 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.24284268 |
| 49 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.19782588 |
| 50 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 3.18197406 |
| 51 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.13492887 |
| 52 | translational termination (GO:0006415) | 3.13102931 |
| 53 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.11166187 |
| 54 | DNA deamination (GO:0045006) | 3.09113713 |
| 55 | cotranslational protein targeting to membrane (GO:0006613) | 3.09087762 |
| 56 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.08486671 |
| 57 | protein targeting to ER (GO:0045047) | 3.06652843 |
| 58 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.06355002 |
| 59 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.06355002 |
| 60 | cell wall macromolecule catabolic process (GO:0016998) | 3.05189457 |
| 61 | presynaptic membrane organization (GO:0097090) | 3.03940967 |
| 62 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.02600870 |
| 63 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.02535333 |
| 64 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.01004501 |
| 65 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.97459284 |
| 66 | mesenchymal cell proliferation (GO:0010463) | 2.96053835 |
| 67 | negative regulation of smoothened signaling pathway (GO:0045879) | 2.94384708 |
| 68 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.93630458 |
| 69 | negative regulation of ligase activity (GO:0051352) | 2.93630458 |
| 70 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.90308502 |
| 71 | ATP biosynthetic process (GO:0006754) | 2.89183811 |
| 72 | forebrain neuron differentiation (GO:0021879) | 2.88562727 |
| 73 | platelet dense granule organization (GO:0060155) | 2.88049562 |
| 74 | positive regulation of vascular permeability (GO:0043117) | 2.87963860 |
| 75 | negative regulation of B cell apoptotic process (GO:0002903) | 2.87694563 |
| 76 | rRNA modification (GO:0000154) | 2.87133775 |
| 77 | negative regulation of mesenchymal cell apoptotic process (GO:2001054) | 2.87078315 |
| 78 | translational elongation (GO:0006414) | 2.85994688 |
| 79 | respiratory chain complex IV assembly (GO:0008535) | 2.85590217 |
| 80 | spliceosomal snRNP assembly (GO:0000387) | 2.84844258 |
| 81 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.84714290 |
| 82 | spliceosomal complex assembly (GO:0000245) | 2.84689806 |
| 83 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.83271960 |
| 84 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.83271960 |
| 85 | protein localization to endoplasmic reticulum (GO:0070972) | 2.82364156 |
| 86 | positive regulation of male gonad development (GO:2000020) | 2.81871850 |
| 87 | oxidative phosphorylation (GO:0006119) | 2.81521272 |
| 88 | positive regulation of tyrosine phosphorylation of Stat1 protein (GO:0042511) | 2.78301271 |
| 89 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.78295693 |
| 90 | regulation of immunoglobulin secretion (GO:0051023) | 2.77439365 |
| 91 | positive regulation of interleukin-17 production (GO:0032740) | 2.77386089 |
| 92 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.77129605 |
| 93 | termination of RNA polymerase III transcription (GO:0006386) | 2.77129605 |
| 94 | central nervous system myelination (GO:0022010) | 2.76724575 |
| 95 | axon ensheathment in central nervous system (GO:0032291) | 2.76724575 |
| 96 | somatic stem cell division (GO:0048103) | 2.74316821 |
| 97 | regulation of transcription from RNA polymerase I promoter (GO:0006356) | 2.71246528 |
| 98 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 2.71192741 |
| 99 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 2.71192741 |
| 100 | regulation of translation, ncRNA-mediated (GO:0045974) | 2.71192741 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.90342899 |
| 2 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.82631090 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.76477895 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.16722723 |
| 5 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.91038012 |
| 6 | VDR_22108803_ChIP-Seq_LS180_Human | 2.88983254 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.84690754 |
| 8 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.84004603 |
| 9 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.64290238 |
| 10 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.45443064 |
| 11 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.40643081 |
| 12 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.34682033 |
| 13 | EWS_26573619_Chip-Seq_HEK293_Human | 2.34411075 |
| 14 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.33448762 |
| 15 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.27399494 |
| 16 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.25115789 |
| 17 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.24897277 |
| 18 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.24774188 |
| 19 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.24632615 |
| 20 | FUS_26573619_Chip-Seq_HEK293_Human | 2.18174605 |
| 21 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.17028273 |
| 22 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.07372104 |
| 23 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.02744457 |
| 24 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.92394145 |
| 25 | P300_19829295_ChIP-Seq_ESCs_Human | 1.83870748 |
| 26 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.83545109 |
| 27 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.78030936 |
| 28 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.75719617 |
| 29 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.75630429 |
| 30 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.70711792 |
| 31 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.69082593 |
| 32 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.67736600 |
| 33 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.67459727 |
| 34 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.67459727 |
| 35 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.64679295 |
| 36 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.64568013 |
| 37 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.63461113 |
| 38 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.59535638 |
| 39 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.58894161 |
| 40 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.53097675 |
| 41 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.52067631 |
| 42 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.49830172 |
| 43 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.48152068 |
| 44 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.45564648 |
| 45 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.43463514 |
| 46 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.42175307 |
| 47 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.39288939 |
| 48 | AR_20517297_ChIP-Seq_VCAP_Human | 1.38711909 |
| 49 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.34584541 |
| 50 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.32941028 |
| 51 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.31338810 |
| 52 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.31338810 |
| 53 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.31273722 |
| 54 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.30587328 |
| 55 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.30120818 |
| 56 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.30070568 |
| 57 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.26281550 |
| 58 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.25575335 |
| 59 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.23690742 |
| 60 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.22824017 |
| 61 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.22105502 |
| 62 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.19827741 |
| 63 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.18934622 |
| 64 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.17712894 |
| 65 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.17321963 |
| 66 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.15792591 |
| 67 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.15777867 |
| 68 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.15470366 |
| 69 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.15344670 |
| 70 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.14133895 |
| 71 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.13452143 |
| 72 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.12634411 |
| 73 | GATA1_22025678_ChIP-Seq_K562_Human | 1.12337946 |
| 74 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.11236047 |
| 75 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.11068953 |
| 76 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.11068953 |
| 77 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.11068953 |
| 78 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.07603842 |
| 79 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.07173220 |
| 80 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.07025839 |
| 81 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.06837659 |
| 82 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.04921340 |
| 83 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.04157676 |
| 84 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.01003796 |
| 85 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.00313681 |
| 86 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.99964440 |
| 87 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.99943251 |
| 88 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.98718180 |
| 89 | RXR_22108803_ChIP-Seq_LS180_Human | 0.98299582 |
| 90 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.96586091 |
| 91 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.94881314 |
| 92 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.94280221 |
| 93 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.93873985 |
| 94 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.93782011 |
| 95 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.93173142 |
| 96 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.93173142 |
| 97 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.93062356 |
| 98 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.93062356 |
| 99 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.90940244 |
| 100 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.90012407 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000566_synostosis | 8.69135080 |
| 2 | MP0003136_yellow_coat_color | 7.01869216 |
| 3 | MP0000372_irregular_coat_pigmentation | 4.12935577 |
| 4 | MP0000537_abnormal_urethra_morphology | 3.35287482 |
| 5 | MP0005171_absent_coat_pigmentation | 2.90293966 |
| 6 | MP0009780_abnormal_chondrocyte_physiolo | 2.60946976 |
| 7 | MP0001299_abnormal_eye_distance/ | 2.57549215 |
| 8 | MP0001346_abnormal_lacrimal_gland | 2.46575439 |
| 9 | MP0002282_abnormal_trachea_morphology | 2.43984355 |
| 10 | MP0005075_abnormal_melanosome_morpholog | 2.41766178 |
| 11 | MP0002938_white_spotting | 2.25559267 |
| 12 | MP0002277_abnormal_respiratory_mucosa | 2.18810336 |
| 13 | MP0005670_abnormal_white_adipose | 2.16644282 |
| 14 | MP0008877_abnormal_DNA_methylation | 2.08477956 |
| 15 | MP0003878_abnormal_ear_physiology | 2.00451852 |
| 16 | MP0005377_hearing/vestibular/ear_phenot | 2.00451852 |
| 17 | MP0010030_abnormal_orbit_morphology | 1.94410907 |
| 18 | MP0005408_hypopigmentation | 1.91876165 |
| 19 | MP0002095_abnormal_skin_pigmentation | 1.90726373 |
| 20 | MP0003646_muscle_fatigue | 1.86503322 |
| 21 | MP0002837_dystrophic_cardiac_calcinosis | 1.77028257 |
| 22 | MP0003122_maternal_imprinting | 1.76372518 |
| 23 | MP0005083_abnormal_biliary_tract | 1.69642118 |
| 24 | MP0005174_abnormal_tail_pigmentation | 1.65296984 |
| 25 | MP0002102_abnormal_ear_morphology | 1.60542135 |
| 26 | MP0004134_abnormal_chest_morphology | 1.59354708 |
| 27 | MP0003787_abnormal_imprinting | 1.59062564 |
| 28 | MP0004957_abnormal_blastocyst_morpholog | 1.57081662 |
| 29 | MP0004142_abnormal_muscle_tone | 1.52570869 |
| 30 | MP0001293_anophthalmia | 1.52318601 |
| 31 | MP0000371_diluted_coat_color | 1.52316424 |
| 32 | MP0002249_abnormal_larynx_morphology | 1.43171014 |
| 33 | MP0000462_abnormal_digestive_system | 1.40984140 |
| 34 | MP0001485_abnormal_pinna_reflex | 1.39693404 |
| 35 | MP0000579_abnormal_nail_morphology | 1.39211821 |
| 36 | MP0005379_endocrine/exocrine_gland_phen | 1.33235356 |
| 37 | MP0000569_abnormal_digit_pigmentation | 1.32321566 |
| 38 | MP0000383_abnormal_hair_follicle | 1.30989087 |
| 39 | MP0000049_abnormal_middle_ear | 1.26530662 |
| 40 | MP0000631_abnormal_neuroendocrine_gland | 1.22340842 |
| 41 | MP0006292_abnormal_olfactory_placode | 1.18721561 |
| 42 | MP0006072_abnormal_retinal_apoptosis | 1.13798035 |
| 43 | MP0003567_abnormal_fetal_cardiomyocyte | 1.13282615 |
| 44 | MP0003121_genomic_imprinting | 1.08546650 |
| 45 | MP0000015_abnormal_ear_pigmentation | 0.98500851 |
| 46 | MP0005187_abnormal_penis_morphology | 0.98399034 |
| 47 | MP0005645_abnormal_hypothalamus_physiol | 0.97502774 |
| 48 | MP0004381_abnormal_hair_follicle | 0.97496646 |
| 49 | MP0002075_abnormal_coat/hair_pigmentati | 0.95321804 |
| 50 | MP0000465_gastrointestinal_hemorrhage | 0.93135746 |
| 51 | MP0000762_abnormal_tongue_morphology | 0.92552484 |
| 52 | MP0003300_gastrointestinal_ulcer | 0.89566860 |
| 53 | MP0005084_abnormal_gallbladder_morpholo | 0.89124863 |
| 54 | MP0002090_abnormal_vision | 0.88067266 |
| 55 | MP0001984_abnormal_olfaction | 0.87780855 |
| 56 | MP0003937_abnormal_limbs/digits/tail_de | 0.87612532 |
| 57 | MP0002653_abnormal_ependyma_morphology | 0.87113983 |
| 58 | MP0010678_abnormal_skin_adnexa | 0.85503022 |
| 59 | MP0000428_abnormal_craniofacial_morphol | 0.84214811 |
| 60 | MP0009379_abnormal_foot_pigmentation | 0.84068465 |
| 61 | MP0000647_abnormal_sebaceous_gland | 0.81107107 |
| 62 | MP0001186_pigmentation_phenotype | 0.80647846 |
| 63 | MP0004885_abnormal_endolymph | 0.79668316 |
| 64 | MP0002233_abnormal_nose_morphology | 0.79477740 |
| 65 | MP0005551_abnormal_eye_electrophysiolog | 0.79427016 |
| 66 | MP0000538_abnormal_urinary_bladder | 0.76408802 |
| 67 | MP0001958_emphysema | 0.76282010 |
| 68 | MP0001324_abnormal_eye_pigmentation | 0.75962220 |
| 69 | MP0003718_maternal_effect | 0.74916364 |
| 70 | MP0000026_abnormal_inner_ear | 0.74610961 |
| 71 | MP0003283_abnormal_digestive_organ | 0.74269843 |
| 72 | MP0005253_abnormal_eye_physiology | 0.73502732 |
| 73 | MP0001286_abnormal_eye_development | 0.71574240 |
| 74 | MP0003693_abnormal_embryo_hatching | 0.70817980 |
| 75 | MP0001853_heart_inflammation | 0.69643286 |
| 76 | MP0009697_abnormal_copulation | 0.69604373 |
| 77 | MP0003938_abnormal_ear_development | 0.67999722 |
| 78 | MP0008058_abnormal_DNA_repair | 0.64179517 |
| 79 | MP0003755_abnormal_palate_morphology | 0.63034918 |
| 80 | MP0001529_abnormal_vocalization | 0.60137584 |
| 81 | MP0001835_abnormal_antigen_presentation | 0.58655246 |
| 82 | MP0003786_premature_aging | 0.57551111 |
| 83 | MP0002166_altered_tumor_susceptibility | 0.57063848 |
| 84 | MP0005503_abnormal_tendon_morphology | 0.55936109 |
| 85 | MP0001666_abnormal_nutrient_absorption | 0.55321809 |
| 86 | MP0009250_abnormal_appendicular_skeleto | 0.54706708 |
| 87 | MP0001963_abnormal_hearing_physiology | 0.54585458 |
| 88 | MP0004270_analgesia | 0.51103657 |
| 89 | MP0002163_abnormal_gland_morphology | 0.49797049 |
| 90 | MP0005671_abnormal_response_to | 0.48783608 |
| 91 | MP0002006_tumorigenesis | 0.48676712 |
| 92 | MP0002751_abnormal_autonomic_nervous | 0.48406300 |
| 93 | MP0002108_abnormal_muscle_morphology | 0.47690582 |
| 94 | MP0002148_abnormal_hypersensitivity_rea | 0.47612750 |
| 95 | MP0008932_abnormal_embryonic_tissue | 0.44508756 |
| 96 | MP0005381_digestive/alimentary_phenotyp | 0.43649998 |
| 97 | MP0000778_abnormal_nervous_system | 0.43556150 |
| 98 | MP0002272_abnormal_nervous_system | 0.42029381 |
| 99 | MP0002111_abnormal_tail_morphology | 0.39459986 |
| 100 | MP0003936_abnormal_reproductive_system | 0.38536382 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Partial duplication of thumb phalanx (HP:0009944) | 6.28801413 |
| 2 | Partial duplication of the phalanx of hand (HP:0009999) | 5.43530838 |
| 3 | Aplasia involving bones of the upper limbs (HP:0009823) | 4.84768857 |
| 4 | Aplasia of the phalanges of the hand (HP:0009802) | 4.84768857 |
| 5 | Aplasia involving bones of the extremities (HP:0009825) | 4.84768857 |
| 6 | Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658) | 4.82617520 |
| 7 | Abnormality of the parietal bone (HP:0002696) | 4.51875160 |
| 8 | Alacrima (HP:0000522) | 4.23620713 |
| 9 | Coronal craniosynostosis (HP:0004440) | 4.19141820 |
| 10 | Neonatal short-limb short stature (HP:0008921) | 4.08246828 |
| 11 | Abnormality of the labia minora (HP:0012880) | 4.04068589 |
| 12 | Abnormality of the middle phalanges of the toes (HP:0010183) | 3.96279495 |
| 13 | Esophageal atresia (HP:0002032) | 3.94860118 |
| 14 | Megalencephaly (HP:0001355) | 3.93754982 |
| 15 | Stenosis of the external auditory canal (HP:0000402) | 3.93749578 |
| 16 | Abnormality of the lacrimal duct (HP:0011481) | 3.73417637 |
| 17 | Nasolacrimal duct obstruction (HP:0000579) | 3.66851236 |
| 18 | Gastrointestinal atresia (HP:0002589) | 3.65116039 |
| 19 | Duplication of thumb phalanx (HP:0009942) | 3.54397803 |
| 20 | Bronchomalacia (HP:0002780) | 3.47807741 |
| 21 | Decreased lacrimation (HP:0000633) | 3.40709509 |
| 22 | Bilateral microphthalmos (HP:0007633) | 3.28555190 |
| 23 | Supernumerary ribs (HP:0005815) | 3.23771613 |
| 24 | Thickened helices (HP:0000391) | 3.21524631 |
| 25 | Recurrent corneal erosions (HP:0000495) | 3.21100463 |
| 26 | Conical tooth (HP:0000698) | 3.19558750 |
| 27 | Bifid scrotum (HP:0000048) | 3.17551132 |
| 28 | Abnormality of the nasolacrimal system (HP:0000614) | 3.12688031 |
| 29 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 3.12314683 |
| 30 | Split foot (HP:0001839) | 3.06834093 |
| 31 | Supernumerary bones of the axial skeleton (HP:0009144) | 3.03066607 |
| 32 | Aqueductal stenosis (HP:0002410) | 2.94754321 |
| 33 | Down-sloping shoulders (HP:0200021) | 2.91652506 |
| 34 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.88583630 |
| 35 | Short 4th metacarpal (HP:0010044) | 2.88583630 |
| 36 | Neoplasm of the heart (HP:0100544) | 2.85879054 |
| 37 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.83474588 |
| 38 | Stomach cancer (HP:0012126) | 2.72742705 |
| 39 | Abnormality of incisor morphology (HP:0011063) | 2.70799458 |
| 40 | Acute necrotizing encephalopathy (HP:0006965) | 2.69903677 |
| 41 | Broad distal phalanx of finger (HP:0009836) | 2.66468927 |
| 42 | Chronic otitis media (HP:0000389) | 2.63027668 |
| 43 | Aplastic anemia (HP:0001915) | 2.62018228 |
| 44 | Humeroradial synostosis (HP:0003041) | 2.60703881 |
| 45 | Synostosis involving the elbow (HP:0003938) | 2.60703881 |
| 46 | Acute encephalopathy (HP:0006846) | 2.60449706 |
| 47 | Intestinal atresia (HP:0011100) | 2.57909265 |
| 48 | Abnormality of the 2nd finger (HP:0004100) | 2.54129360 |
| 49 | Septo-optic dysplasia (HP:0100842) | 2.53634687 |
| 50 | Short phalanx of the thumb (HP:0009660) | 2.52726394 |
| 51 | Medulloblastoma (HP:0002885) | 2.47310265 |
| 52 | Broad metatarsal (HP:0001783) | 2.41536529 |
| 53 | Cupped ear (HP:0000378) | 2.40816878 |
| 54 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.39333802 |
| 55 | Absent radius (HP:0003974) | 2.37197536 |
| 56 | Progressive macrocephaly (HP:0004481) | 2.36988624 |
| 57 | Xerostomia (HP:0000217) | 2.35804681 |
| 58 | Absent septum pellucidum (HP:0001331) | 2.34295206 |
| 59 | Vertebral fusion (HP:0002948) | 2.29765121 |
| 60 | Choanal stenosis (HP:0000452) | 2.28759524 |
| 61 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.26330600 |
| 62 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 2.25821525 |
| 63 | Short hallux (HP:0010109) | 2.24451798 |
| 64 | Absent forearm bone (HP:0003953) | 2.24409341 |
| 65 | Aplasia involving forearm bones (HP:0009822) | 2.24409341 |
| 66 | Preaxial foot polydactyly (HP:0001841) | 2.23376202 |
| 67 | Fused cervical vertebrae (HP:0002949) | 2.21564285 |
| 68 | Abnormality of the septum pellucidum (HP:0007375) | 2.20011023 |
| 69 | Hypoplasia of the ulna (HP:0003022) | 2.19945992 |
| 70 | Mixed hearing impairment (HP:0000410) | 2.19066842 |
| 71 | Abnormality of the salivary glands (HP:0010286) | 2.14806152 |
| 72 | Hamartoma (HP:0010566) | 2.14468670 |
| 73 | Congenital, generalized hypertrichosis (HP:0004540) | 2.14397845 |
| 74 | Abnormality of the antihelix (HP:0009738) | 2.12908950 |
| 75 | Taurodontia (HP:0000679) | 2.11060204 |
| 76 | Abnormality of permanent molar morphology (HP:0011071) | 2.11060204 |
| 77 | Abnormality of the dental root (HP:0006486) | 2.11060204 |
| 78 | Abnormality of methionine metabolism (HP:0010901) | 2.10781386 |
| 79 | Mitochondrial inheritance (HP:0001427) | 2.10233820 |
| 80 | 2-3 toe syndactyly (HP:0004691) | 2.09592143 |
| 81 | Sleep apnea (HP:0010535) | 2.06970690 |
| 82 | Abnormality of the incisor (HP:0000676) | 2.06287365 |
| 83 | Abnormality of the 4th metacarpal (HP:0010012) | 2.04470848 |
| 84 | Abnormality of the costochondral junction (HP:0000919) | 2.04074944 |
| 85 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.03059122 |
| 86 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 1.99812434 |
| 87 | Vaginal atresia (HP:0000148) | 1.99806485 |
| 88 | Anophthalmia (HP:0000528) | 1.99420327 |
| 89 | True hermaphroditism (HP:0010459) | 1.96938483 |
| 90 | Overriding aorta (HP:0002623) | 1.96031021 |
| 91 | Increased hepatocellular lipid droplets (HP:0006565) | 1.95818089 |
| 92 | Abnormality of molar (HP:0011077) | 1.94998551 |
| 93 | Abnormality of molar morphology (HP:0011070) | 1.94998551 |
| 94 | Increased CSF lactate (HP:0002490) | 1.93001054 |
| 95 | Genital tract atresia (HP:0001827) | 1.92464672 |
| 96 | Tracheomalacia (HP:0002779) | 1.91311857 |
| 97 | Abnormal sex determination (HP:0012244) | 1.87027429 |
| 98 | Sex reversal (HP:0012245) | 1.87027429 |
| 99 | 11 pairs of ribs (HP:0000878) | 1.86420712 |
| 100 | Abnormal lung lobation (HP:0002101) | 1.83010335 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FGFR2 | 6.89483031 |
| 2 | PINK1 | 3.68071225 |
| 3 | NUAK1 | 3.59405059 |
| 4 | LATS1 | 3.23815075 |
| 5 | BUB1 | 2.85136253 |
| 6 | MST4 | 2.61153053 |
| 7 | FGFR1 | 2.60634550 |
| 8 | VRK2 | 2.48718782 |
| 9 | PNCK | 2.30628697 |
| 10 | ZAK | 2.19464699 |
| 11 | TXK | 2.14221860 |
| 12 | NME1 | 2.07498468 |
| 13 | WEE1 | 2.07107105 |
| 14 | PASK | 1.96580558 |
| 15 | MAP4K2 | 1.91295139 |
| 16 | STK16 | 1.87648248 |
| 17 | ADRBK2 | 1.83475407 |
| 18 | MKNK1 | 1.79695273 |
| 19 | TLK1 | 1.75187323 |
| 20 | FGFR3 | 1.73043045 |
| 21 | VRK1 | 1.51014878 |
| 22 | SRPK1 | 1.50976964 |
| 23 | CASK | 1.50556847 |
| 24 | STK38L | 1.43666976 |
| 25 | MAP3K6 | 1.32276232 |
| 26 | TAF1 | 1.28846666 |
| 27 | EPHA3 | 1.26488400 |
| 28 | TSSK6 | 1.25070967 |
| 29 | NEK1 | 1.21112315 |
| 30 | FRK | 1.17509861 |
| 31 | PLK3 | 1.17362323 |
| 32 | WNK3 | 1.14808544 |
| 33 | CSNK1G3 | 1.12964108 |
| 34 | CSNK1G1 | 1.12963879 |
| 35 | STK3 | 1.10416216 |
| 36 | BCR | 1.05542807 |
| 37 | CSNK1A1L | 1.03508116 |
| 38 | LIMK1 | 1.03341126 |
| 39 | KDR | 1.00478044 |
| 40 | PDK2 | 0.95126598 |
| 41 | BMPR2 | 0.92042331 |
| 42 | MKNK2 | 0.89401686 |
| 43 | CSNK1G2 | 0.89350415 |
| 44 | BMPR1B | 0.87114282 |
| 45 | EIF2AK2 | 0.85898212 |
| 46 | ADRBK1 | 0.83042546 |
| 47 | TIE1 | 0.80153188 |
| 48 | PLK1 | 0.79266189 |
| 49 | NEK9 | 0.78382816 |
| 50 | PAK4 | 0.73677102 |
| 51 | TNK2 | 0.72740292 |
| 52 | MAP2K3 | 0.68856761 |
| 53 | GRK1 | 0.68481950 |
| 54 | TAOK3 | 0.63337782 |
| 55 | PLK2 | 0.62602439 |
| 56 | OXSR1 | 0.62030108 |
| 57 | EPHB2 | 0.61549290 |
| 58 | TRIM28 | 0.60604257 |
| 59 | DYRK2 | 0.60222154 |
| 60 | MAPKAPK5 | 0.60211866 |
| 61 | TEC | 0.59815140 |
| 62 | NME2 | 0.59792250 |
| 63 | BCKDK | 0.59113847 |
| 64 | ACVR1B | 0.58572611 |
| 65 | ROCK1 | 0.55659334 |
| 66 | CDK3 | 0.54701939 |
| 67 | CDC7 | 0.51007588 |
| 68 | TESK2 | 0.46712853 |
| 69 | TGFBR1 | 0.45424674 |
| 70 | PLK4 | 0.45240174 |
| 71 | MAP2K6 | 0.44849052 |
| 72 | PTK6 | 0.44397780 |
| 73 | TTK | 0.42754995 |
| 74 | YES1 | 0.41127541 |
| 75 | ALK | 0.39698208 |
| 76 | MAP3K4 | 0.39639536 |
| 77 | PRKCG | 0.39262925 |
| 78 | RPS6KA5 | 0.39246232 |
| 79 | INSRR | 0.38494080 |
| 80 | UHMK1 | 0.37929166 |
| 81 | MINK1 | 0.37736518 |
| 82 | CSNK2A2 | 0.37134067 |
| 83 | STK4 | 0.35494869 |
| 84 | PRKCH | 0.33809561 |
| 85 | MAP3K5 | 0.33037885 |
| 86 | GRK6 | 0.32184884 |
| 87 | AKT2 | 0.32110962 |
| 88 | MAP2K4 | 0.31373171 |
| 89 | ERBB3 | 0.31325578 |
| 90 | ERBB2 | 0.30490414 |
| 91 | CSNK1E | 0.29627213 |
| 92 | WNK4 | 0.29123058 |
| 93 | CSNK2A1 | 0.28928467 |
| 94 | ZAP70 | 0.28706290 |
| 95 | MAPK13 | 0.27490275 |
| 96 | CAMK2A | 0.26757398 |
| 97 | IGF1R | 0.26377296 |
| 98 | ERBB4 | 0.25729284 |
| 99 | PRKG1 | 0.25379217 |
| 100 | JAK1 | 0.24389726 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.75504165 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 4.10090734 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.04144017 |
| 4 | Protein export_Homo sapiens_hsa03060 | 4.00130882 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 3.10631182 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.74916488 |
| 7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.49837660 |
| 8 | Basal transcription factors_Homo sapiens_hsa03022 | 2.42381806 |
| 9 | Huntingtons disease_Homo sapiens_hsa05016 | 2.07098916 |
| 10 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.01994079 |
| 11 | Spliceosome_Homo sapiens_hsa03040 | 1.95061855 |
| 12 | Alzheimers disease_Homo sapiens_hsa05010 | 1.87629707 |
| 13 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.78711293 |
| 14 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.65791017 |
| 15 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.57875448 |
| 16 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.55759793 |
| 17 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.48856108 |
| 18 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.47141705 |
| 19 | RNA transport_Homo sapiens_hsa03013 | 1.46323744 |
| 20 | RNA degradation_Homo sapiens_hsa03018 | 1.44800306 |
| 21 | Asthma_Homo sapiens_hsa05310 | 1.44414507 |
| 22 | Mismatch repair_Homo sapiens_hsa03430 | 1.41112401 |
| 23 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.39971647 |
| 24 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.33763297 |
| 25 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.33635156 |
| 26 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.32436137 |
| 27 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.27572175 |
| 28 | Purine metabolism_Homo sapiens_hsa00230 | 1.26544744 |
| 29 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.24657547 |
| 30 | DNA replication_Homo sapiens_hsa03030 | 1.21342960 |
| 31 | Phototransduction_Homo sapiens_hsa04744 | 1.19532541 |
| 32 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.18145843 |
| 33 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.12420098 |
| 34 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.03203320 |
| 35 | Homologous recombination_Homo sapiens_hsa03440 | 1.02851481 |
| 36 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.01415588 |
| 37 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.00131904 |
| 38 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.98473089 |
| 39 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.96744107 |
| 40 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.92805482 |
| 41 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.92310825 |
| 42 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.90959525 |
| 43 | Peroxisome_Homo sapiens_hsa04146 | 0.90413780 |
| 44 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.89788952 |
| 45 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.89426821 |
| 46 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.88834247 |
| 47 | Allograft rejection_Homo sapiens_hsa05330 | 0.88189112 |
| 48 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.88125742 |
| 49 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.83856586 |
| 50 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.80089497 |
| 51 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.79329811 |
| 52 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.76566876 |
| 53 | Retinol metabolism_Homo sapiens_hsa00830 | 0.74871269 |
| 54 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.74097689 |
| 55 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.72625433 |
| 56 | Metabolic pathways_Homo sapiens_hsa01100 | 0.72202936 |
| 57 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.66405797 |
| 58 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.65286428 |
| 59 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.63606450 |
| 60 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.63049164 |
| 61 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.61092892 |
| 62 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.60637326 |
| 63 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.60482031 |
| 64 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.59702257 |
| 65 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.58966874 |
| 66 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.56774183 |
| 67 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.55011087 |
| 68 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.54017513 |
| 69 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.53776349 |
| 70 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.53616869 |
| 71 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.53483710 |
| 72 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.53422042 |
| 73 | Mineral absorption_Homo sapiens_hsa04978 | 0.52908747 |
| 74 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.51939615 |
| 75 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.49826364 |
| 76 | Cell cycle_Homo sapiens_hsa04110 | 0.47378377 |
| 77 | Olfactory transduction_Homo sapiens_hsa04740 | 0.46262312 |
| 78 | Base excision repair_Homo sapiens_hsa03410 | 0.45450201 |
| 79 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.44970122 |
| 80 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.44079459 |
| 81 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.43960686 |
| 82 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.40034924 |
| 83 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.38954475 |
| 84 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.38153425 |
| 85 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.37990511 |
| 86 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.36956138 |
| 87 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.36777390 |
| 88 | Nicotine addiction_Homo sapiens_hsa05033 | 0.33122163 |
| 89 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.30393383 |
| 90 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.29950808 |
| 91 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.29368519 |
| 92 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.27443591 |
| 93 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.27271737 |
| 94 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.26095625 |
| 95 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.26091367 |
| 96 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.26030942 |
| 97 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.25989466 |
| 98 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.22302799 |
| 99 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.18810648 |
| 100 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.18148338 |

