

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | kynurenine metabolic process (GO:0070189) | 8.39837709 |
| 2 | tryptophan catabolic process (GO:0006569) | 7.10564882 |
| 3 | indole-containing compound catabolic process (GO:0042436) | 7.10564882 |
| 4 | indolalkylamine catabolic process (GO:0046218) | 7.10564882 |
| 5 | tryptophan metabolic process (GO:0006568) | 6.14058812 |
| 6 | amine catabolic process (GO:0009310) | 4.87437617 |
| 7 | cellular biogenic amine catabolic process (GO:0042402) | 4.87437617 |
| 8 | indolalkylamine metabolic process (GO:0006586) | 4.81537385 |
| 9 | DNA deamination (GO:0045006) | 4.78228874 |
| 10 | cellular response to exogenous dsRNA (GO:0071360) | 4.45917167 |
| 11 | rRNA modification (GO:0000154) | 4.27012948 |
| 12 | cytochrome complex assembly (GO:0017004) | 4.21767968 |
| 13 | organelle disassembly (GO:1903008) | 4.14437899 |
| 14 | GMP metabolic process (GO:0046037) | 4.12812994 |
| 15 | respiratory chain complex IV assembly (GO:0008535) | 4.07485620 |
| 16 | positive regulation of defense response to virus by host (GO:0002230) | 4.06677633 |
| 17 | piRNA metabolic process (GO:0034587) | 4.05036515 |
| 18 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.82685892 |
| 19 | rRNA methylation (GO:0031167) | 3.74309285 |
| 20 | metallo-sulfur cluster assembly (GO:0031163) | 3.61690364 |
| 21 | iron-sulfur cluster assembly (GO:0016226) | 3.61690364 |
| 22 | mitochondrial RNA metabolic process (GO:0000959) | 3.57456091 |
| 23 | negative regulation of T cell differentiation in thymus (GO:0033085) | 3.56253472 |
| 24 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.54950028 |
| 25 | protein deneddylation (GO:0000338) | 3.54947877 |
| 26 | aromatic amino acid family catabolic process (GO:0009074) | 3.52795678 |
| 27 | benzene-containing compound metabolic process (GO:0042537) | 3.49676003 |
| 28 | adenosine metabolic process (GO:0046085) | 3.46607700 |
| 29 | DNA double-strand break processing (GO:0000729) | 3.46094296 |
| 30 | regulation of chronic inflammatory response (GO:0002676) | 3.45607647 |
| 31 | protein complex biogenesis (GO:0070271) | 3.44049614 |
| 32 | cullin deneddylation (GO:0010388) | 3.41134259 |
| 33 | positive regulation of mitochondrial fission (GO:0090141) | 3.35541621 |
| 34 | interferon-gamma secretion (GO:0072643) | 3.34231810 |
| 35 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.30877088 |
| 36 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.30877088 |
| 37 | response to pheromone (GO:0019236) | 3.28572205 |
| 38 | L-methionine salvage (GO:0071267) | 3.28531205 |
| 39 | L-methionine biosynthetic process (GO:0071265) | 3.28531205 |
| 40 | amino acid salvage (GO:0043102) | 3.28531205 |
| 41 | regulation of defense response to virus by host (GO:0050691) | 3.27312700 |
| 42 | transcription from mitochondrial promoter (GO:0006390) | 3.23738823 |
| 43 | oxidative phosphorylation (GO:0006119) | 3.22833467 |
| 44 | mannosylation (GO:0097502) | 3.21816424 |
| 45 | regulation of thymocyte apoptotic process (GO:0070243) | 3.21622397 |
| 46 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.21335695 |
| 47 | indole-containing compound metabolic process (GO:0042430) | 3.19449550 |
| 48 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.17264151 |
| 49 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.10052956 |
| 50 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.10052956 |
| 51 | protein polyglutamylation (GO:0018095) | 3.04109275 |
| 52 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.03968371 |
| 53 | methionine biosynthetic process (GO:0009086) | 3.03503256 |
| 54 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.01095792 |
| 55 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.97108312 |
| 56 | DNA methylation involved in gamete generation (GO:0043046) | 2.91160612 |
| 57 | mitochondrial DNA replication (GO:0006264) | 2.88951581 |
| 58 | ubiquinone biosynthetic process (GO:0006744) | 2.86438622 |
| 59 | ribonucleoprotein complex disassembly (GO:0032988) | 2.85110670 |
| 60 | NAD biosynthetic process (GO:0009435) | 2.84113449 |
| 61 | pseudouridine synthesis (GO:0001522) | 2.82285020 |
| 62 | aggressive behavior (GO:0002118) | 2.82284698 |
| 63 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 2.81618250 |
| 64 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 2.81271844 |
| 65 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc | 2.81068203 |
| 66 | inositol phosphate dephosphorylation (GO:0046855) | 2.74198187 |
| 67 | phosphorylated carbohydrate dephosphorylation (GO:0046838) | 2.74198187 |
| 68 | chaperone-mediated protein transport (GO:0072321) | 2.73352264 |
| 69 | tRNA modification (GO:0006400) | 2.72928505 |
| 70 | non-recombinational repair (GO:0000726) | 2.72405498 |
| 71 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.72405498 |
| 72 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.72203119 |
| 73 | behavioral response to nicotine (GO:0035095) | 2.71121327 |
| 74 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.69042813 |
| 75 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.68501075 |
| 76 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.68501075 |
| 77 | cellular response to dsRNA (GO:0071359) | 2.68147711 |
| 78 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.67668816 |
| 79 | isotype switching (GO:0045190) | 2.67668816 |
| 80 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.67668816 |
| 81 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 2.67664274 |
| 82 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 2.67664274 |
| 83 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 2.67664274 |
| 84 | purine nucleobase biosynthetic process (GO:0009113) | 2.65588243 |
| 85 | ubiquinone metabolic process (GO:0006743) | 2.65556629 |
| 86 | purine nucleotide salvage (GO:0032261) | 2.63976942 |
| 87 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.63814553 |
| 88 | NADH dehydrogenase complex assembly (GO:0010257) | 2.63814553 |
| 89 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.63814553 |
| 90 | protein K6-linked ubiquitination (GO:0085020) | 2.63745904 |
| 91 | positive regulation of prostaglandin secretion (GO:0032308) | 2.62974937 |
| 92 | histone H2A ubiquitination (GO:0033522) | 2.61674231 |
| 93 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.61507928 |
| 94 | thrombin receptor signaling pathway (GO:0070493) | 2.61492286 |
| 95 | methionine metabolic process (GO:0006555) | 2.59734835 |
| 96 | S-adenosylmethionine metabolic process (GO:0046500) | 2.57462682 |
| 97 | regulation of germinal center formation (GO:0002634) | 2.54940973 |
| 98 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.54210819 |
| 99 | cellular response to ATP (GO:0071318) | 2.54204046 |
| 100 | peptidyl-histidine modification (GO:0018202) | 2.53033308 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 4.85969344 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.05800510 |
| 3 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 4.02346271 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.74606185 |
| 5 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.54486649 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.28639101 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.99082174 |
| 8 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.83765315 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.81953688 |
| 10 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.57998563 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.53104916 |
| 12 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.45240956 |
| 13 | VDR_22108803_ChIP-Seq_LS180_Human | 2.42521776 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.37816567 |
| 15 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.19015714 |
| 16 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.18435095 |
| 17 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.08792076 |
| 18 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.06271512 |
| 19 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.04201150 |
| 20 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.99699061 |
| 21 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.98854763 |
| 22 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.97054394 |
| 23 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.92810517 |
| 24 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.91124073 |
| 25 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.86908913 |
| 26 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.86355288 |
| 27 | EWS_26573619_Chip-Seq_HEK293_Human | 1.84673116 |
| 28 | FUS_26573619_Chip-Seq_HEK293_Human | 1.83353025 |
| 29 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.81247621 |
| 30 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.78051650 |
| 31 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.75107138 |
| 32 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.74456312 |
| 33 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.71652604 |
| 34 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.67040405 |
| 35 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.61703013 |
| 36 | GATA3_26560356_Chip-Seq_TH2_Human | 1.58121708 |
| 37 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.55246268 |
| 38 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.54146896 |
| 39 | AR_20517297_ChIP-Seq_VCAP_Human | 1.51948969 |
| 40 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.51641499 |
| 41 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.50852949 |
| 42 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.50132835 |
| 43 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.49684435 |
| 44 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.39405556 |
| 45 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.38249631 |
| 46 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.35632907 |
| 47 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.33697426 |
| 48 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.33025874 |
| 49 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.30886181 |
| 50 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.30608915 |
| 51 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.29135084 |
| 52 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.28771573 |
| 53 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.28754694 |
| 54 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.28754694 |
| 55 | MYB_26560356_Chip-Seq_TH2_Human | 1.27981167 |
| 56 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.25540834 |
| 57 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.23477392 |
| 58 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.22665132 |
| 59 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.22076931 |
| 60 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.21302056 |
| 61 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.21302056 |
| 62 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.20711632 |
| 63 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.19919659 |
| 64 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.19919659 |
| 65 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.18129120 |
| 66 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.14801009 |
| 67 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.07853624 |
| 68 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.07626069 |
| 69 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.07136300 |
| 70 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.05209587 |
| 71 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.05209574 |
| 72 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.04879588 |
| 73 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03583792 |
| 74 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.02918475 |
| 75 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.02825404 |
| 76 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.02005453 |
| 77 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.01512033 |
| 78 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.99303728 |
| 79 | NCOR_22424771_ChIP-Seq_293T_Human | 0.99289279 |
| 80 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.99247282 |
| 81 | GATA3_26560356_Chip-Seq_TH1_Human | 0.99044634 |
| 82 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.97698864 |
| 83 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.97588504 |
| 84 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.96236791 |
| 85 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.91946286 |
| 86 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.91482730 |
| 87 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.91400184 |
| 88 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.90397065 |
| 89 | P300_19829295_ChIP-Seq_ESCs_Human | 0.90105182 |
| 90 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.89926784 |
| 91 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.89193688 |
| 92 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.88439767 |
| 93 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.87355813 |
| 94 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.84667556 |
| 95 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.84180955 |
| 96 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.82119773 |
| 97 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.81746958 |
| 98 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.81501053 |
| 99 | ERA_21632823_ChIP-Seq_H3396_Human | 0.81006305 |
| 100 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.78917542 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008875_abnormal_xenobiotic_pharmacok | 4.84954946 |
| 2 | MP0006072_abnormal_retinal_apoptosis | 3.74908783 |
| 3 | MP0008877_abnormal_DNA_methylation | 3.69377846 |
| 4 | MP0008058_abnormal_DNA_repair | 3.07117407 |
| 5 | MP0003724_increased_susceptibility_to | 2.83477596 |
| 6 | MP0008775_abnormal_heart_ventricle | 2.60266449 |
| 7 | MP0003806_abnormal_nucleotide_metabolis | 2.20972202 |
| 8 | MP0002006_tumorigenesis | 2.15069778 |
| 9 | MP0003718_maternal_effect | 2.06175776 |
| 10 | MP0008872_abnormal_physiological_respon | 2.01991388 |
| 11 | MP0002166_altered_tumor_susceptibility | 2.00901659 |
| 12 | MP0002148_abnormal_hypersensitivity_rea | 1.98998077 |
| 13 | MP0005671_abnormal_response_to | 1.98065615 |
| 14 | MP0002138_abnormal_hepatobiliary_system | 1.97710432 |
| 15 | MP0001835_abnormal_antigen_presentation | 1.93198515 |
| 16 | MP0009764_decreased_sensitivity_to | 1.90610514 |
| 17 | MP0005084_abnormal_gallbladder_morpholo | 1.79202530 |
| 18 | MP0010094_abnormal_chromosome_stability | 1.73851288 |
| 19 | MP0000685_abnormal_immune_system | 1.71814654 |
| 20 | MP0005551_abnormal_eye_electrophysiolog | 1.70529918 |
| 21 | MP0005646_abnormal_pituitary_gland | 1.66628869 |
| 22 | MP0005253_abnormal_eye_physiology | 1.65644503 |
| 23 | MP0006036_abnormal_mitochondrial_physio | 1.60225964 |
| 24 | MP0001905_abnormal_dopamine_level | 1.54636754 |
| 25 | MP0006276_abnormal_autonomic_nervous | 1.53603251 |
| 26 | MP0002009_preneoplasia | 1.43835570 |
| 27 | MP0005389_reproductive_system_phenotype | 1.41274058 |
| 28 | MP0001501_abnormal_sleep_pattern | 1.39987552 |
| 29 | MP0005645_abnormal_hypothalamus_physiol | 1.39286701 |
| 30 | MP0004043_abnormal_pH_regulation | 1.38856922 |
| 31 | MP0002282_abnormal_trachea_morphology | 1.36869386 |
| 32 | MP0001986_abnormal_taste_sensitivity | 1.36470662 |
| 33 | MP0006292_abnormal_olfactory_placode | 1.34878709 |
| 34 | MP0003252_abnormal_bile_duct | 1.34808105 |
| 35 | MP0004147_increased_porphyrin_level | 1.32899006 |
| 36 | MP0000383_abnormal_hair_follicle | 1.30942242 |
| 37 | MP0004145_abnormal_muscle_electrophysio | 1.30316289 |
| 38 | MP0001968_abnormal_touch/_nociception | 1.30141121 |
| 39 | MP0005410_abnormal_fertilization | 1.25426527 |
| 40 | MP0003195_calcinosis | 1.23285019 |
| 41 | MP0003646_muscle_fatigue | 1.22712848 |
| 42 | MP0001293_anophthalmia | 1.22065712 |
| 43 | MP0004215_abnormal_myocardial_fiber | 1.18074887 |
| 44 | MP0001764_abnormal_homeostasis | 1.17934530 |
| 45 | MP0002160_abnormal_reproductive_system | 1.16109021 |
| 46 | MP0010386_abnormal_urinary_bladder | 1.15645481 |
| 47 | MP0004885_abnormal_endolymph | 1.15628034 |
| 48 | MP0001529_abnormal_vocalization | 1.15488669 |
| 49 | MP0002876_abnormal_thyroid_physiology | 1.15038922 |
| 50 | MP0002452_abnormal_antigen_presenting | 1.13736292 |
| 51 | MP0003693_abnormal_embryo_hatching | 1.12748502 |
| 52 | MP0010368_abnormal_lymphatic_system | 1.12642273 |
| 53 | MP0000230_abnormal_systemic_arterial | 1.12212667 |
| 54 | MP0001800_abnormal_humoral_immune | 1.11272017 |
| 55 | MP0001919_abnormal_reproductive_system | 1.09352269 |
| 56 | MP0002234_abnormal_pharynx_morphology | 1.08630230 |
| 57 | MP0002733_abnormal_thermal_nociception | 1.08247506 |
| 58 | MP0003186_abnormal_redox_activity | 1.08181666 |
| 59 | MP0005165_increased_susceptibility_to | 1.04421447 |
| 60 | MP0000689_abnormal_spleen_morphology | 1.04306671 |
| 61 | MP0004133_heterotaxia | 1.04170252 |
| 62 | MP0002102_abnormal_ear_morphology | 1.02376018 |
| 63 | MP0002723_abnormal_immune_serum | 1.01523777 |
| 64 | MP0003763_abnormal_thymus_physiology | 1.01006106 |
| 65 | MP0003880_abnormal_central_pattern | 1.00299923 |
| 66 | MP0005000_abnormal_immune_tolerance | 1.00272181 |
| 67 | MP0000372_irregular_coat_pigmentation | 0.99268708 |
| 68 | MP0003436_decreased_susceptibility_to | 0.96767812 |
| 69 | MP0001970_abnormal_pain_threshold | 0.95529869 |
| 70 | MP0009046_muscle_twitch | 0.93948024 |
| 71 | MP0001819_abnormal_immune_cell | 0.93444707 |
| 72 | MP0009765_abnormal_xenobiotic_induced | 0.90873757 |
| 73 | MP0002420_abnormal_adaptive_immunity | 0.89045427 |
| 74 | MP0009785_altered_susceptibility_to | 0.88609414 |
| 75 | MP0004142_abnormal_muscle_tone | 0.87281243 |
| 76 | MP0006035_abnormal_mitochondrial_morpho | 0.86442536 |
| 77 | MP0003786_premature_aging | 0.85357055 |
| 78 | MP0009745_abnormal_behavioral_response | 0.84795255 |
| 79 | MP0004084_abnormal_cardiac_muscle | 0.84493408 |
| 80 | MP0000427_abnormal_hair_cycle | 0.81682588 |
| 81 | MP0010678_abnormal_skin_adnexa | 0.81556296 |
| 82 | MP0002396_abnormal_hematopoietic_system | 0.81412751 |
| 83 | MP0002272_abnormal_nervous_system | 0.81376771 |
| 84 | MP0003866_abnormal_defecation | 0.81031927 |
| 85 | MP0005636_abnormal_mineral_homeostasis | 0.79271124 |
| 86 | MP0010155_abnormal_intestine_physiology | 0.79151057 |
| 87 | MP0001486_abnormal_startle_reflex | 0.76726706 |
| 88 | MP0000653_abnormal_sex_gland | 0.74814195 |
| 89 | MP0003011_delayed_dark_adaptation | 0.74530618 |
| 90 | MP0002837_dystrophic_cardiac_calcinosis | 0.74145272 |
| 91 | MP0001929_abnormal_gametogenesis | 0.73574577 |
| 92 | MP0003075_altered_response_to | 0.72154088 |
| 93 | MP0002722_abnormal_immune_system | 0.71221411 |
| 94 | MP0001845_abnormal_inflammatory_respons | 0.70186735 |
| 95 | MP0002638_abnormal_pupillary_reflex | 0.69562299 |
| 96 | MP0002751_abnormal_autonomic_nervous | 0.69140444 |
| 97 | MP0005167_abnormal_blood-brain_barrier | 0.68144119 |
| 98 | MP0005387_immune_system_phenotype | 0.67843378 |
| 99 | MP0001790_abnormal_immune_system | 0.67843378 |
| 100 | MP0004782_abnormal_surfactant_physiolog | 0.67622221 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 3.84664693 |
| 2 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 3.72023567 |
| 3 | Lipid accumulation in hepatocytes (HP:0006561) | 3.59218607 |
| 4 | Hepatocellular necrosis (HP:0001404) | 3.59049229 |
| 5 | Prostate neoplasm (HP:0100787) | 3.51202940 |
| 6 | Abolished electroretinogram (ERG) (HP:0000550) | 3.37686314 |
| 7 | Abnormality of the prostate (HP:0008775) | 3.36361343 |
| 8 | Increased CSF lactate (HP:0002490) | 3.19510215 |
| 9 | Hepatic necrosis (HP:0002605) | 3.19361970 |
| 10 | 3-Methylglutaconic aciduria (HP:0003535) | 3.17038697 |
| 11 | Mitochondrial inheritance (HP:0001427) | 3.15031323 |
| 12 | Pancreatic cysts (HP:0001737) | 3.08609324 |
| 13 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 3.08164869 |
| 14 | Type 2 muscle fiber atrophy (HP:0003554) | 3.06070308 |
| 15 | Adactyly (HP:0009776) | 3.05057825 |
| 16 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 3.03456454 |
| 17 | Fibular aplasia (HP:0002990) | 3.02558887 |
| 18 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 3.01811433 |
| 19 | Increased hepatocellular lipid droplets (HP:0006565) | 2.86568616 |
| 20 | Pancreatic fibrosis (HP:0100732) | 2.86125776 |
| 21 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.80890824 |
| 22 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.80056185 |
| 23 | Hypoplasia of the uterus (HP:0000013) | 2.75177098 |
| 24 | Increased serum lactate (HP:0002151) | 2.73829255 |
| 25 | Acute necrotizing encephalopathy (HP:0006965) | 2.72408726 |
| 26 | Abnormality of the middle phalanges of the toes (HP:0010183) | 2.72251568 |
| 27 | Decreased central vision (HP:0007663) | 2.64607752 |
| 28 | Opisthotonus (HP:0002179) | 2.62815713 |
| 29 | Methylmalonic acidemia (HP:0002912) | 2.61221399 |
| 30 | Muscle fiber atrophy (HP:0100295) | 2.59457094 |
| 31 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.57576690 |
| 32 | Progressive macrocephaly (HP:0004481) | 2.45502034 |
| 33 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.44148728 |
| 34 | Increased muscle lipid content (HP:0009058) | 2.39566892 |
| 35 | Lactic acidosis (HP:0003128) | 2.39544075 |
| 36 | Attenuation of retinal blood vessels (HP:0007843) | 2.38309548 |
| 37 | Congenital stationary night blindness (HP:0007642) | 2.37886285 |
| 38 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.37376909 |
| 39 | Acute encephalopathy (HP:0006846) | 2.36920479 |
| 40 | Type II lissencephaly (HP:0007260) | 2.34898025 |
| 41 | Cerebellar dysplasia (HP:0007033) | 2.34611902 |
| 42 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.34207826 |
| 43 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 2.33198155 |
| 44 | Spastic paraparesis (HP:0002313) | 2.31534959 |
| 45 | Abnormality of the renal cortex (HP:0011035) | 2.30626588 |
| 46 | Conjunctival hamartoma (HP:0100780) | 2.27113617 |
| 47 | Increased intramyocellular lipid droplets (HP:0012240) | 2.22590806 |
| 48 | Hyperglycinemia (HP:0002154) | 2.22020217 |
| 49 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.20026414 |
| 50 | Hyperglycinuria (HP:0003108) | 2.18132261 |
| 51 | Abnormality of the pons (HP:0007361) | 2.17090655 |
| 52 | Nephronophthisis (HP:0000090) | 2.16316228 |
| 53 | Tubulointerstitial abnormality (HP:0001969) | 2.16191990 |
| 54 | Abnormality of male internal genitalia (HP:0000022) | 2.15681884 |
| 55 | Abnormality of alanine metabolism (HP:0010916) | 2.15656917 |
| 56 | Hyperalaninemia (HP:0003348) | 2.15656917 |
| 57 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.15656917 |
| 58 | Cerebral edema (HP:0002181) | 2.13417816 |
| 59 | Progressive microcephaly (HP:0000253) | 2.13032094 |
| 60 | Methylmalonic aciduria (HP:0012120) | 2.12813234 |
| 61 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 2.11752700 |
| 62 | True hermaphroditism (HP:0010459) | 2.09916878 |
| 63 | Stomach cancer (HP:0012126) | 2.08744858 |
| 64 | Posterior subcapsular cataract (HP:0007787) | 2.06020564 |
| 65 | Progressive inability to walk (HP:0002505) | 2.05057172 |
| 66 | Congenital, generalized hypertrichosis (HP:0004540) | 2.03724368 |
| 67 | Tubulointerstitial fibrosis (HP:0005576) | 2.03183816 |
| 68 | Abnormality of the renal medulla (HP:0100957) | 2.02531595 |
| 69 | Hypoplasia of the pons (HP:0012110) | 2.00403786 |
| 70 | Renal cortical cysts (HP:0000803) | 1.98821428 |
| 71 | Absent/shortened dynein arms (HP:0200106) | 1.98069484 |
| 72 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.98069484 |
| 73 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 1.97752118 |
| 74 | Ketosis (HP:0001946) | 1.97179766 |
| 75 | Supernumerary spleens (HP:0009799) | 1.95665840 |
| 76 | Asplenia (HP:0001746) | 1.95155487 |
| 77 | Lethargy (HP:0001254) | 1.94101119 |
| 78 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.93833902 |
| 79 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.93448965 |
| 80 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.93386794 |
| 81 | Abnormality of glycine metabolism (HP:0010895) | 1.93386794 |
| 82 | Renal Fanconi syndrome (HP:0001994) | 1.92590865 |
| 83 | Pendular nystagmus (HP:0012043) | 1.92043608 |
| 84 | Microvesicular hepatic steatosis (HP:0001414) | 1.90034234 |
| 85 | Abnormality of macular pigmentation (HP:0008002) | 1.89678915 |
| 86 | Polydipsia (HP:0001959) | 1.89363932 |
| 87 | Abnormal drinking behavior (HP:0030082) | 1.89363932 |
| 88 | Panhypogammaglobulinemia (HP:0003139) | 1.89006268 |
| 89 | CNS demyelination (HP:0007305) | 1.87300807 |
| 90 | Tubulointerstitial nephritis (HP:0001970) | 1.87096588 |
| 91 | Chronic otitis media (HP:0000389) | 1.85796822 |
| 92 | Abnormality of midbrain morphology (HP:0002418) | 1.84424005 |
| 93 | Molar tooth sign on MRI (HP:0002419) | 1.84424005 |
| 94 | Abnormality of the 2nd finger (HP:0004100) | 1.83348510 |
| 95 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.83204392 |
| 96 | Dicarboxylic aciduria (HP:0003215) | 1.83204392 |
| 97 | Anhidrosis (HP:0000970) | 1.83178341 |
| 98 | Colon cancer (HP:0003003) | 1.82609928 |
| 99 | Emotional lability (HP:0000712) | 1.82198498 |
| 100 | Respiratory failure (HP:0002878) | 1.81883875 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STK16 | 4.33739817 |
| 2 | TAOK3 | 3.92165599 |
| 3 | ZAK | 3.53360854 |
| 4 | EIF2AK1 | 3.45158133 |
| 5 | EIF2AK3 | 3.24624324 |
| 6 | NUAK1 | 3.17768735 |
| 7 | VRK2 | 2.66079325 |
| 8 | MAP4K2 | 2.51174043 |
| 9 | FRK | 2.41160159 |
| 10 | BCKDK | 2.23782979 |
| 11 | MKNK1 | 2.14516807 |
| 12 | TLK1 | 2.14114911 |
| 13 | MAPKAPK3 | 1.94653112 |
| 14 | VRK1 | 1.90849731 |
| 15 | MST4 | 1.86158387 |
| 16 | TRIM28 | 1.78828346 |
| 17 | SRPK1 | 1.78041848 |
| 18 | MAPKAPK5 | 1.73241700 |
| 19 | PBK | 1.64532388 |
| 20 | NME2 | 1.61209348 |
| 21 | MAP3K14 | 1.60830629 |
| 22 | ADRBK2 | 1.59337532 |
| 23 | TAF1 | 1.55674982 |
| 24 | EIF2AK2 | 1.47370671 |
| 25 | FES | 1.45189688 |
| 26 | MAP3K4 | 1.45026064 |
| 27 | WNK4 | 1.39930300 |
| 28 | PLK3 | 1.37797967 |
| 29 | BMPR1B | 1.36378278 |
| 30 | TXK | 1.28431890 |
| 31 | TIE1 | 1.28178914 |
| 32 | CSNK1G3 | 1.24579789 |
| 33 | GRK1 | 1.22701847 |
| 34 | TEC | 1.21996434 |
| 35 | CSNK1A1L | 1.17804275 |
| 36 | PHKG2 | 1.13256236 |
| 37 | PHKG1 | 1.13256236 |
| 38 | DAPK1 | 1.08861647 |
| 39 | CAMKK2 | 1.05869362 |
| 40 | PINK1 | 1.04950336 |
| 41 | KIT | 1.01253186 |
| 42 | IRAK4 | 0.98274726 |
| 43 | ERBB3 | 0.95045469 |
| 44 | ITK | 0.92339501 |
| 45 | CSNK1G2 | 0.91703600 |
| 46 | PLK4 | 0.89725747 |
| 47 | IKBKB | 0.89092530 |
| 48 | FLT3 | 0.88988083 |
| 49 | PRKCQ | 0.86741124 |
| 50 | TBK1 | 0.86652712 |
| 51 | CSNK1G1 | 0.85982814 |
| 52 | MAP2K2 | 0.85194809 |
| 53 | GRK5 | 0.84702139 |
| 54 | NEK1 | 0.79829076 |
| 55 | OXSR1 | 0.76163948 |
| 56 | MATK | 0.74905527 |
| 57 | SYK | 0.74087109 |
| 58 | CSF1R | 0.66151874 |
| 59 | PLK2 | 0.65893357 |
| 60 | INSRR | 0.65305921 |
| 61 | MAP2K7 | 0.62057704 |
| 62 | BCR | 0.61806511 |
| 63 | WNK3 | 0.61684458 |
| 64 | RPS6KA5 | 0.61289779 |
| 65 | PASK | 0.58056865 |
| 66 | DYRK2 | 0.56394196 |
| 67 | STK39 | 0.55454319 |
| 68 | MAP4K1 | 0.52540215 |
| 69 | TNIK | 0.52453696 |
| 70 | ATR | 0.52190158 |
| 71 | BTK | 0.51373379 |
| 72 | IKBKE | 0.51149242 |
| 73 | LYN | 0.50287423 |
| 74 | CDK19 | 0.47128549 |
| 75 | TNK2 | 0.45929900 |
| 76 | GRK6 | 0.45571777 |
| 77 | KDR | 0.42114750 |
| 78 | EPHA3 | 0.41489458 |
| 79 | PIK3CA | 0.40845670 |
| 80 | ADRBK1 | 0.40357688 |
| 81 | NEK6 | 0.40046288 |
| 82 | MAPK13 | 0.39824212 |
| 83 | LCK | 0.39273512 |
| 84 | STK38L | 0.37912390 |
| 85 | CHEK2 | 0.35187721 |
| 86 | CDC7 | 0.33626934 |
| 87 | PAK6 | 0.33040304 |
| 88 | TGFBR1 | 0.32500436 |
| 89 | ABL1 | 0.31881513 |
| 90 | RPS6KB2 | 0.31619376 |
| 91 | CAMKK1 | 0.31563825 |
| 92 | CSNK1A1 | 0.30430715 |
| 93 | PLK1 | 0.28413581 |
| 94 | NEK9 | 0.27969131 |
| 95 | TSSK6 | 0.27896673 |
| 96 | PRKCE | 0.27632540 |
| 97 | IGF1R | 0.26253723 |
| 98 | MAPK7 | 0.25270183 |
| 99 | HCK | 0.25196336 |
| 100 | PTK2B | 0.24672821 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Caffeine metabolism_Homo sapiens_hsa00232 | 8.38977862 |
| 2 | Asthma_Homo sapiens_hsa05310 | 3.05788820 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 2.63133402 |
| 4 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.30647028 |
| 5 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.30199642 |
| 6 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.85704055 |
| 7 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.85439002 |
| 8 | Allograft rejection_Homo sapiens_hsa05330 | 1.84563902 |
| 9 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.72717128 |
| 10 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.70813322 |
| 11 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.69926947 |
| 12 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.58227808 |
| 13 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.57139659 |
| 14 | Protein export_Homo sapiens_hsa03060 | 1.55649528 |
| 15 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.55496408 |
| 16 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.51948466 |
| 17 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.49810286 |
| 18 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.49802897 |
| 19 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.45003916 |
| 20 | Parkinsons disease_Homo sapiens_hsa05012 | 1.42667981 |
| 21 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.39695162 |
| 22 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.37406963 |
| 23 | Phototransduction_Homo sapiens_hsa04744 | 1.34831319 |
| 24 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.33822461 |
| 25 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.25380821 |
| 26 | Mismatch repair_Homo sapiens_hsa03430 | 1.24251334 |
| 27 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.21912931 |
| 28 | RNA degradation_Homo sapiens_hsa03018 | 1.19673013 |
| 29 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.16450388 |
| 30 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.15288871 |
| 31 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.14568171 |
| 32 | Spliceosome_Homo sapiens_hsa03040 | 1.13358882 |
| 33 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.12134606 |
| 34 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.11871768 |
| 35 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.07886051 |
| 36 | RNA polymerase_Homo sapiens_hsa03020 | 1.06351460 |
| 37 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.04199316 |
| 38 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.03332252 |
| 39 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.02423591 |
| 40 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.01594094 |
| 41 | Homologous recombination_Homo sapiens_hsa03440 | 0.99713114 |
| 42 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.99165014 |
| 43 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.96395039 |
| 44 | Ribosome_Homo sapiens_hsa03010 | 0.95529866 |
| 45 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.94994038 |
| 46 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.94051602 |
| 47 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.94024866 |
| 48 | Purine metabolism_Homo sapiens_hsa00230 | 0.93441059 |
| 49 | RNA transport_Homo sapiens_hsa03013 | 0.93416891 |
| 50 | Peroxisome_Homo sapiens_hsa04146 | 0.93344379 |
| 51 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.92688011 |
| 52 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.91634059 |
| 53 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.91382743 |
| 54 | Basal transcription factors_Homo sapiens_hsa03022 | 0.88292734 |
| 55 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.81873553 |
| 56 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.81843996 |
| 57 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.81843458 |
| 58 | DNA replication_Homo sapiens_hsa03030 | 0.80868242 |
| 59 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.80484690 |
| 60 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.79898549 |
| 61 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.79622245 |
| 62 | Base excision repair_Homo sapiens_hsa03410 | 0.73944043 |
| 63 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.73341362 |
| 64 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.72259165 |
| 65 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.72162479 |
| 66 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.71610683 |
| 67 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.69370901 |
| 68 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.67219567 |
| 69 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.63551071 |
| 70 | Salivary secretion_Homo sapiens_hsa04970 | 0.63023292 |
| 71 | Alzheimers disease_Homo sapiens_hsa05010 | 0.62873649 |
| 72 | Olfactory transduction_Homo sapiens_hsa04740 | 0.61127100 |
| 73 | Huntingtons disease_Homo sapiens_hsa05016 | 0.59690541 |
| 74 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.57625330 |
| 75 | Leishmaniasis_Homo sapiens_hsa05140 | 0.57294369 |
| 76 | Taste transduction_Homo sapiens_hsa04742 | 0.53596940 |
| 77 | Metabolic pathways_Homo sapiens_hsa01100 | 0.52411050 |
| 78 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.50978832 |
| 79 | Morphine addiction_Homo sapiens_hsa05032 | 0.50066009 |
| 80 | Retinol metabolism_Homo sapiens_hsa00830 | 0.48407427 |
| 81 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.47466217 |
| 82 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.44642666 |
| 83 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.44297295 |
| 84 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.44233487 |
| 85 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.42210098 |
| 86 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.39887414 |
| 87 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.38419648 |
| 88 | Carbon metabolism_Homo sapiens_hsa01200 | 0.37459345 |
| 89 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.37301933 |
| 90 | Circadian entrainment_Homo sapiens_hsa04713 | 0.36367724 |
| 91 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.35352829 |
| 92 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.34111559 |
| 93 | Nicotine addiction_Homo sapiens_hsa05033 | 0.33836900 |
| 94 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.32402153 |
| 95 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.31112402 |
| 96 | Renin secretion_Homo sapiens_hsa04924 | 0.29514505 |
| 97 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.28216027 |
| 98 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.26868121 |
| 99 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.25655015 |
| 100 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.23534242 |

