ARCHS4

Functional Annotation Prediction

Predicted biological processes (GO)

Rank	Gene Set	Z-score
1	DNA unwinding involved in DNA replication (GO:0006268)	5.66876751
2	establishment of integrated proviral latency (GO:0075713)	5.16866547
3	mitotic sister chromatid cohesion (GO:0007064)	4.80216213
4	regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091	4.57059121
5	protein localization to kinetochore (GO:0034501)	4.43754420
6	DNA topological change (GO:0006265)	4.35489811
7	* negative regulation of mRNA splicing, via spliceosome (GO:0048025)	4.34647374
8	kinetochore organization (GO:0051383)	4.27828490
9	sister chromatid segregation (GO:0000819)	4.17132608
10	ribosome assembly (GO:0042255)	4.16435273
11	nuclear pore organization (GO:0006999)	4.13302765
12	DNA ligation (GO:0006266)	4.13214578
13	mitotic chromosome condensation (GO:0007076)	4.08849129
14	nuclear pore complex assembly (GO:0051292)	4.06190360
15	* negative regulation of RNA splicing (GO:0033119)	4.05345209
16	regulation of centriole replication (GO:0046599)	4.04324396
17	DNA strand elongation involved in DNA replication (GO:0006271)	4.02909960
18	alternative mRNA splicing, via spliceosome (GO:0000380)	3.91838210
19	heterochromatin organization (GO:0070828)	3.89276360
20	DNA strand elongation (GO:0022616)	3.86001571
21	protein localization to chromosome, centromeric region (GO:0071459)	3.82318558
22	mitotic sister chromatid segregation (GO:0000070)	3.80036547
23	* negative regulation of mRNA processing (GO:0050686)	3.78812292
24	regulation of sister chromatid cohesion (GO:0007063)	3.75125110
25	DNA replication initiation (GO:0006270)	3.73916545
26	establishment of viral latency (GO:0019043)	3.69330654
27	DNA duplex unwinding (GO:0032508)	3.69272058
28	DNA geometric change (GO:0032392)	3.67492098
29	dosage compensation (GO:0007549)	3.64894349
30	mitotic recombination (GO:0006312)	3.63430797
31	DNA replication-independent nucleosome assembly (GO:0006336)	3.62803739
32	DNA replication-independent nucleosome organization (GO:0034724)	3.62803739
33	protein complex localization (GO:0031503)	3.62336082
34	non-recombinational repair (GO:0000726)	3.62162165
35	double-strand break repair via nonhomologous end joining (GO:0006303)	3.62162165
36	telomere maintenance via semi-conservative replication (GO:0032201)	3.59378580
37	* mRNA splicing, via spliceosome (GO:0000398)	3.58334626
38	* RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)	3.58334626
39	regulation of attachment of spindle microtubules to kinetochore (GO:0051988)	3.56071024
40	mitotic nuclear envelope disassembly (GO:0007077)	3.53669237
41	* RNA splicing, via transesterification reactions (GO:0000375)	3.52957821
42	formation of translation preinitiation complex (GO:0001731)	3.52075667
43	IMP metabolic process (GO:0046040)	3.51258418
44	kinetochore assembly (GO:0051382)	3.47593303
45	regulation of DNA endoreduplication (GO:0032875)	3.46434145
46	translesion synthesis (GO:0019985)	3.45981671
47	mitotic metaphase plate congression (GO:0007080)	3.45004675
48	CENP-A containing nucleosome assembly (GO:0034080)	3.43636772
49	chromatin remodeling at centromere (GO:0031055)	3.43344940
50	attachment of spindle microtubules to kinetochore (GO:0008608)	3.40852299
51	ATP-dependent chromatin remodeling (GO:0043044)	3.40662492
52	DNA replication checkpoint (GO:0000076)	3.37784844
53	telomere maintenance via recombination (GO:0000722)	3.37132968
54	regulation of mitotic spindle organization (GO:0060236)	3.35991952
55	DNA replication-dependent nucleosome assembly (GO:0006335)	3.35307597
56	DNA replication-dependent nucleosome organization (GO:0034723)	3.35307597
57	metaphase plate congression (GO:0051310)	3.33970766
58	mRNA splice site selection (GO:0006376)	3.30724778
59	termination of RNA polymerase II transcription (GO:0006369)	3.30105000
60	RNA stabilization (GO:0043489)	3.30039856
61	mRNA stabilization (GO:0048255)	3.30039856
62	nuclear envelope disassembly (GO:0051081)	3.29717161
63	membrane disassembly (GO:0030397)	3.29717161
64	* negative regulation of mRNA metabolic process (GO:1903312)	3.27927845
65	regulation of RNA export from nucleus (GO:0046831)	3.27587103
66	purine nucleobase biosynthetic process (GO:0009113)	3.24741892
67	regulation of centrosome cycle (GO:0046605)	3.24702982
68	glucocorticoid receptor signaling pathway (GO:0042921)	3.21583595
69	pre-miRNA processing (GO:0031054)	3.20864735
70	DNA conformation change (GO:0071103)	3.19014634
71	postreplication repair (GO:0006301)	3.14970455
72	regulation of chromosome segregation (GO:0051983)	3.14721545
73	meiotic chromosome segregation (GO:0045132)	3.14649332
74	regulation of translational fidelity (GO:0006450)	3.14238556
75	cellular protein complex localization (GO:0034629)	3.13988181
76	chromatin assembly or disassembly (GO:0006333)	3.13710508
77	spindle assembly checkpoint (GO:0071173)	3.12725045
78	RNA export from nucleus (GO:0006405)	3.12328785
79	histone exchange (GO:0043486)	3.11737033
80	V(D)J recombination (GO:0033151)	3.10703075
81	mRNA export from nucleus (GO:0006406)	3.09876918
82	nucleobase biosynthetic process (GO:0046112)	3.09644781
83	regulation of transcription from RNA polymerase I promoter (GO:0006356)	3.09305646
84	establishment of chromosome localization (GO:0051303)	3.07686963
85	regulation of centrosome duplication (GO:0010824)	3.07482993
86	negative regulation of histone methylation (GO:0031061)	3.07442934
87	L-serine metabolic process (GO:0006563)	3.07417366
88	3-UTR-mediated mRNA stabilization (GO:0070935)	3.05958198
89	protein localization to chromosome (GO:0034502)	3.05899429
90	regulation of spindle organization (GO:0090224)	3.04960055
91	mitotic spindle assembly checkpoint (GO:0007094)	3.04824334
92	positive regulation of chromosome segregation (GO:0051984)	3.03639849
93	histone H2A acetylation (GO:0043968)	3.03619951
94	spliceosomal tri-snRNP complex assembly (GO:0000244)	3.02020783
95	negative regulation of mitotic sister chromatid separation (GO:2000816)	3.01804836
96	negative regulation of mitotic sister chromatid segregation (GO:0033048)	3.01804836
97	negative regulation of mitotic metaphase/anaphase transition (GO:0045841)	3.01804836
98	negative regulation of sister chromatid segregation (GO:0033046)	3.01804836
99	telomere maintenance via telomere lengthening (GO:0010833)	3.01470826
100	negative regulation of chromosome segregation (GO:0051985)	3.01135736
101	nucleotide-excision repair, DNA gap filling (GO:0006297)	3.00642155
102	positive regulation of cell cycle checkpoint (GO:1901978)	3.00239766
103	regulation of mitotic metaphase/anaphase transition (GO:0030071)	2.98782611
104	spindle checkpoint (GO:0031577)	2.97866175
105	folic acid-containing compound biosynthetic process (GO:0009396)	2.97669871
106	pore complex assembly (GO:0046931)	2.97306479
107	regulation of mRNA stability (GO:0043488)	2.96487045
108	regulation of DNA damage checkpoint (GO:2000001)	2.95452804
109	positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)	2.94779741
110	chromosome segregation (GO:0007059)	2.94144256
111	IMP biosynthetic process (GO:0006188)	2.92146424
112	mRNA transport (GO:0051028)	2.90664673
113	mitotic spindle checkpoint (GO:0071174)	2.90420594
114	negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)	2.90415952
115	regulation of metaphase/anaphase transition of cell cycle (GO:1902099)	2.90050796
116	positive regulation of RNA splicing (GO:0033120)	2.90044405
117	protein-DNA complex disassembly (GO:0032986)	2.89355094
118	nucleosome disassembly (GO:0006337)	2.89355094
119	chromosome condensation (GO:0030261)	2.87629570
120	regulation of histone H3-K9 methylation (GO:0051570)	2.86618663
121	regulation of mitotic sister chromatid separation (GO:0010965)	2.86429779
122	regulation of mitotic sister chromatid segregation (GO:0033047)	2.86429779
123	regulation of sister chromatid segregation (GO:0033045)	2.86429779
124	positive regulation of histone H3-K4 methylation (GO:0051571)	2.86127290

Predicted upstream transcription factors (ChEA)

Rank	Gene Set	Z-score
1	* FOXM1_23109430_ChIP-Seq_U2OS_Human	6.15875816
2	E2F4_17652178_ChIP-ChIP_JURKAT_Human	4.68638169
3	* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human	3.81106177
4	EGR1_19374776_ChIP-ChIP_THP-1_Human	3.60720371
5	MYC_18555785_ChIP-Seq_MESCs_Mouse	3.51226529
6	EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse	3.04734093
7	MYC_22102868_ChIP-Seq_BL_Human	2.83302573
8	* KDM5B_21448134_ChIP-Seq_MESCs_Mouse	2.81139824
9	AR_21909140_ChIP-Seq_LNCAP_Human	2.61137158
10	E2F1_21310950_ChIP-Seq_MCF-7_Human	2.51772207
11	MYC_19079543_ChIP-ChIP_MESCs_Mouse	2.47595404
12	TP63_19390658_ChIP-ChIP_HaCaT_Human	2.41188419
13	* CIITA_25753668_ChIP-Seq_RAJI_Human	2.37306157
14	MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse	2.36377476
15	MYC_19030024_ChIP-ChIP_MESCs_Mouse	2.35140652
16	* XRN2_22483619_ChIP-Seq_HELA_Human	2.25342160
17	HCFC1_20581084_ChIP-Seq_MESCs_Mouse	2.21884699
18	NELFA_20434984_ChIP-Seq_ESCs_Mouse	2.16599974
19	RBPJ_22232070_ChIP-Seq_NCS_Mouse	2.14640313
20	EST1_17652178_ChIP-ChIP_JURKAT_Human	2.05703414
21	* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse	2.02254607
22	E2F7_22180533_ChIP-Seq_HELA_Human	11.0644842
23	MYC_18358816_ChIP-ChIP_MESCs_Mouse	1.95819028
24	MYBL2_22936984_ChIP-ChIP_MESCs_Mouse	1.89971383
25	PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse	1.89876669
26	KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human	1.87181227
27	HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse	1.83796585
28	MYCN_18555785_ChIP-Seq_MESCs_Mouse	1.81076240
29	ELF1_17652178_ChIP-ChIP_JURKAT_Human	1.79086546
30	CREB1_15753290_ChIP-ChIP_HEK293T_Human	1.77464602
31	* VDR_23849224_ChIP-Seq_CD4+_Human	1.71483077
32	* TTF2_22483619_ChIP-Seq_HELA_Human	1.71346863
33	FOXP3_21729870_ChIP-Seq_TREG_Human	1.69896998
34	ETS1_20019798_ChIP-Seq_JURKAT_Human	1.68755842
35	ASXL1_24218140_ChIP-Seq_BMDM_Mouse	1.65681378
36	CHD1_19587682_ChIP-ChIP_MESCs_Mouse	1.64943561
37	ZFX_18555785_ChIP-Seq_MESCs_Mouse	1.64771348
38	E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse	1.64770941
39	CCND1_20090754_ChIP-ChIP_RETINA_Mouse	1.61752734
40	KDM5A_27292631_Chip-Seq_BREAST_Human	1.60326993
41	ELK1_19687146_ChIP-ChIP_HELA_Human	1.58931969
42	NANOG_18700969_ChIP-ChIP_MESCs_Mouse	1.58548326
43	POU5F1_18555785_ChIP-Seq_MESCs_Mouse	1.57412792
44	VDR_21846776_ChIP-Seq_THP-1_Human	1.55278882
45	* TAL1_20887958_ChIP-Seq_HPC-7_Mouse	1.51940685
46	GABP_17652178_ChIP-ChIP_JURKAT_Human	1.51813159
47	NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse	1.49330141
48	SALL1_21062744_ChIP-ChIP_HESCs_Human	1.46527476
49	SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse	1.45621067
50	THAP11_20581084_ChIP-Seq_MESCs_Mouse	1.44998926
51	GABP_19822575_ChIP-Seq_HepG2_Human	1.44275945
52	* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat	1.43722317
53	* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse	1.41673927
54	DCP1A_22483619_ChIP-Seq_HELA_Human	1.39232456
55	* PADI4_21655091_ChIP-ChIP_MCF-7_Human	1.38016584
56	HOXB4_20404135_ChIP-ChIP_EML_Mouse	1.37487055
57	MYCN_21190229_ChIP-Seq_SHEP-21N_Human	1.32594117
58	E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human	1.32179418
59	E2F1_18555785_ChIP-Seq_MESCs_Mouse	1.30965208
60	KLF2_18264089_ChIP-ChIP_MESCs_Mouse	1.29794232
61	KLF5_18264089_ChIP-ChIP_MESCs_Mouse	1.29794232
62	KLF4_18264089_ChIP-ChIP_MESCs_Mouse	1.29794232
63	* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse	1.28491623
64	POU5F1_18700969_ChIP-ChIP_MESCs_Mouse	1.28473750
65	PRDM5_23873026_ChIP-Seq_MEFs_Mouse	1.26611225
66	HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse	1.22449818
67	SALL4_18804426_ChIP-ChIP_MESCs_Mouse	1.21960801
68	JARID1A_20064375_ChIP-Seq_MESCs_Mouse	1.21680001
69	SOX2_18555785_ChIP-Seq_MESCs_Mouse	1.20855866
70	SFPI1_20887958_ChIP-Seq_HPC-7_Mouse	1.19541289
71	CLOCK_20551151_ChIP-Seq_293T_Human	1.17218640
72	NANOG_16153702_ChIP-ChIP_HESCs_Human	1.16727233
73	DMRT1_21621532_ChIP-ChIP_FETAL_Ovary	1.14955064
74	TCF3_18467660_ChIP-ChIP_MESCs_Mouse	1.13096049
75	TCF3_18692474_ChIP-Seq_MEFs_Mouse	1.12633439
76	NACC1_18358816_ChIP-ChIP_MESCs_Mouse	1.12115977
77	ZFP281_18358816_ChIP-ChIP_MESCs_Mouse	1.10528423
78	ZFP42_18358816_ChIP-ChIP_MESCs_Mouse	1.09782460
79	WT1_19549856_ChIP-ChIP_CCG9911_Human	1.09618549
80	POU5F1_18358816_ChIP-ChIP_MESCs_Mouse	1.09029898
81	PKCTHETA_26484144_Chip-Seq_BREAST_Human	1.07167987
82	ERG_20887958_ChIP-Seq_HPC-7_Mouse	1.06839164
83	NANOG_18555785_ChIP-Seq_MESCs_Mouse	1.05460650
84	NANOG_21062744_ChIP-ChIP_HESCs_Human	1.05420822
85	SOX17_20123909_ChIP-Seq_XEN_Mouse	1.04719200
86	TFEB_21752829_ChIP-Seq_HELA_Human	1.04587459
87	GFI1B_20887958_ChIP-Seq_HPC-7_Mouse	1.03540368
88	* TCF7_22412390_ChIP-Seq_EML_Mouse	1.02143553
89	UTX_26944678_Chip-Seq_JUKART_Human	1.00460497
90	POU5F1_16153702_ChIP-ChIP_HESCs_Human	1.00215221
91	KLF4_19030024_ChIP-ChIP_MESCs_Mouse	1.00196325
92	CHD1_26751641_Chip-Seq_LNCaP_Human	0.99752964
93	* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse	0.99730411
94	KLF4_18555785_ChIP-Seq_MESCs_Mouse	0.96345274
95	SOX2_19030024_ChIP-ChIP_MESCs_Mouse	0.95587664
96	ASH2L_23239880_ChIP-Seq_MESCs_Mouse	0.94666440
97	DACH1_20351289_ChIP-Seq_MDA-MB-231_Human	0.94615969
98	MYB_26560356_Chip-Seq_TH2_Human	0.94419896
99	SPI1_22096565_ChIP-ChIP_GC-B_Mouse	0.93697815
100	TRIM28_19339689_ChIP-ChIP_MESCs_Mouse	0.91961859
101	SCL_19346495_ChIP-Seq_HPC-7_Human	0.91372575
102	CNOT3_19339689_ChIP-ChIP_MESCs_Mouse	0.89289559
103	STAT3_1855785_ChIP-Seq_MESCs_Mouse	0.87944400
104	HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human	0.87664647
105	MAF_26560356_Chip-Seq_TH1_Human	0.85749334
106	* EWS_26573619_Chip-Seq_HEK293_Human	0.85588664
107	ESR1_15608294_ChIP-ChIP_MCF-7_Human	0.84715503
108	KDM2B_26808549_Chip-Seq_HPB-ALL_Human	0.84155612
109	* DMRT1_23473982_ChIP-Seq_TESTES_Mouse	0.83969076
110	MYB_26560356_Chip-Seq_TH1_Human	0.83740661
111	SOX2_16153702_ChIP-ChIP_HESCs_Human	0.83197242
112	NOTCH1_17114293_ChIP-ChIP_T-ALL_Human	0.83053299
113	FOXP3_17237761_ChIP-ChIP_TREG_Mouse	0.82521341
114	ZFP322A_24550733_ChIP-Seq_MESCs_Mouse	0.81846916
115	SOX9_22984422_ChIP-ChIP_TESTIS_Rat	0.81213563
116	SPI1_23547873_ChIP-Seq_NB4_Human	0.79330383
117	TCF3_18692474_ChIP-Seq_MESCs_Mouse	0.79187797
118	MYC_18940864_ChIP-ChIP_HL60_Human	0.78889809
119	CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human	0.77230730
120	TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse	0.76409649
121	KDM2B_26808549_Chip-Seq_SIL-ALL_Human	0.75853835
122	FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human	0.75495425
123	YY1_21170310_ChIP-Seq_MESCs_Mouse	0.73622900

Predicted mouse phenotypes (MGI)

Rank	Gene Set	Z-score
1	MP0010094_abnormal_chromosome_stability	4.01323812
2	MP0003111_abnormal_nucleus_morphology	3.50577099
3	MP0003693_abnormal_embryo_hatching	3.47316946
4	MP0008057_abnormal_DNA_replication	3.29623358
5	MP0003077_abnormal_cell_cycle	3.20002513
6	MP0004957_abnormal_blastocyst_morpholog	3.09815958
7	MP0003123_paternal_imprinting	2.89685305
8	MP0003121_genomic_imprinting	2.59999942
9	MP0000537_abnormal_urethra_morphology	2.48913406
10	MP0008007_abnormal_cellular_replicative	2.43867768
11	MP0002396_abnormal_hematopoietic_system	2.39874838
12	MP0008058_abnormal_DNA_repair	2.32521985
13	MP0008877_abnormal_DNA_methylation	2.20098090
14	MP0010030_abnormal_orbit_morphology	2.13418508
15	MP0009053_abnormal_anal_canal	2.09483546
16	MP0008932_abnormal_embryonic_tissue	2.07223747
17	MP0005076_abnormal_cell_differentiation	2.06012898
18	MP0000350_abnormal_cell_proliferation	2.02952157
19	MP0001730_embryonic_growth_arrest	2.02752332
20	MP0003941_abnormal_skin_development	1.92133703
21	MP0004808_abnormal_hematopoietic_stem	1.89663751
22	MP0000566_synostosis	1.81585258
23	MP0010352_gastrointestinal_tract_polyps	1.81446500
24	MP0006054_spinal_hemorrhage	1.79218216
25	MP0004197_abnormal_fetal_growth/weight/	1.78532432
26	MP0003122_maternal_imprinting	1.73058945
27	MP0002084_abnormal_developmental_patter	1.70442487
28	MP0001697_abnormal_embryo_size	1.66634204
29	MP0002877_abnormal_melanocyte_morpholog	1.66557990
30	MP0001672_abnormal_embryogenesis/_devel	1.65958418
31	MP0005380_embryogenesis_phenotype	1.65958418
32	MP0002085_abnormal_embryonic_tissue	1.64676714
33	MP0000569_abnormal_digit_pigmentation	1.62648728
34	MP0003984_embryonic_growth_retardation	1.57781474
35	MP0003567_abnormal_fetal_cardiomyocyte	1.56579608
36	MP0002088_abnormal_embryonic_growth/wei	1.54979120
37	MP0003890_abnormal_embryonic-extraembry	1.54897794
38	MP0003787_abnormal_imprinting	1.51710168
39	MP0002938_white_spotting	1.50416620
40	MP0010307_abnormal_tumor_latency	1.45170024
41	MP0001293_anophthalmia	1.44806102
42	MP0002080_prenatal_lethality	1.42319881
43	MP0000428_abnormal_craniofacial_morphol	1.38262096
44	MP0002009_preneoplasia	1.38029805
45	MP0002086_abnormal_extraembryonic_tissu	1.34977292
46	MP0000703_abnormal_thymus_morphology	1.32018295
47	MP0000490_abnormal_crypts_of	1.31746109
48	MP0003115_abnormal_respiratory_system	1.31334055
49	MP0001188_hyperpigmentation	1.28207670
50	MP0003937_abnormal_limbs/digits/tail_de	1.26371164
51	MP0009697_abnormal_copulation	1.25150037
52	MP0003315_abnormal_perineum_morphology	1.24967258
53	MP0009278_abnormal_bone_marrow	1.23126055
54	MP0004185_abnormal_adipocyte_glucose	1.19116248
55	MP0009672_abnormal_birth_weight	1.16810027
56	MP0000313_abnormal_cell_death	1.14531235
57	MP0003119_abnormal_digestive_system	1.14424788
58	MP0000579_abnormal_nail_morphology	1.11945417
59	MP0003763_abnormal_thymus_physiology	1.11769839
60	MP0003718_maternal_effect	1.10735790
61	MP0000049_abnormal_middle_ear	1.08526070
62	MP0003935_abnormal_craniofacial_develop	1.07768826
63	MP0009703_decreased_birth_body	1.07585475
64	MP0002092_abnormal_eye_morphology	1.05985488
65	MP0002653_abnormal_ependyma_morphology	1.04919672
66	MP0003786_premature_aging	1.04332359
67	MP0003385_abnormal_body_wall	1.02900497
68	MP0005187_abnormal_penis_morphology	1.02632220
69	MP0000733_abnormal_muscle_development	1.01946309
70	MP0003221_abnormal_cardiomyocyte_apopto	1.01872859
71	MP0006292_abnormal_olfactory_placode	1.01384178
72	MP0002282_abnormal_trachea_morphology	1.00746677
73	MP0002932_abnormal_joint_morphology	1.00435412
74	MP0002210_abnormal_sex_determination	1.00399449
75	MP0010234_abnormal_vibrissa_follicle	0.99636099
76	MP0002019_abnormal_tumor_incidence	0.99406910
77	MP0001346_abnormal_lacrimal_gland	0.98004499
78	MP0002398_abnormal_bone_marrow	0.96774922
79	MP0003861_abnormal_nervous_system	0.95649414
80	MP0001177_atelectasis	0.95534323
81	MP0001286_abnormal_eye_development	0.93541402
82	MP0003942_abnormal_urinary_system	0.93509109
83	MP0002234_abnormal_pharynx_morphology	0.92885082
84	MP0003283_abnormal_digestive_organ	0.92352052
85	MP0003755_abnormal_palate_morphology	0.90778253
86	MP0002697_abnormal_eye_size	0.90347260
87	MP0000383_abnormal_hair_follicle	0.89100854
88	MP0008789_abnormal_olfactory_epithelium	0.88287016
89	MP0002116_abnormal_craniofacial_bone	0.88105178
90	MP0002111_abnormal_tail_morphology	0.87961886
91	MP0001849_ear_inflammation	0.87511587
92	MP0005394_taste/olfaction_phenotype	0.87465092
93	MP0005499_abnormal_olfactory_system	0.87465092
94	MP0001145_abnormal_male_reproductive	0.84713486
95	MP0000432_abnormal_head_morphology	0.84422735
96	MP0003938_abnormal_ear_development	0.81728830
97	MP0002796_impaired_skin_barrier	0.81676641
98	MP0004264_abnormal_extraembryonic_tissu	0.80369248
99	MP0002925_abnormal_cardiovascular_devel	0.80088683
100	MP0005397_hematopoietic_system_phenotyp	0.79575864
101	MP0001545_abnormal_hematopoietic_system	0.79575864
102	MP0002114_abnormal_axial_skeleton	0.78361152
103	MP0003943_abnormal_hepatobiliary_system	0.77582375
104	MP0005621_abnormal_cell_physiology	0.77183466
105	MP0005384_cellular_phenotype	0.76898167
106	MP0002722_abnormal_immune_system	0.76417656
107	MP0001299_abnormal_eye_distance/	0.75903397
108	MP0000762_abnormal_tongue_morphology	0.73661814
109	MP0005501_abnormal_skin_physiology	0.73321155
110	MP0001915_intracranial_hemorrhage	0.73253030
111	MP0002233_abnormal_nose_morphology	0.71457752
112	MP0004233_abnormal_muscle_weight	0.71357492
113	MP0002081_perinatal_lethality	0.71330141
114	MP0002095_abnormal_skin_pigmentation	0.71225249
115	MP0000465_gastrointestinal_hemorrhage	0.70285668
116	MP0010678_abnormal_skin_adnexa	0.69764289
117	MP0003705_abnormal_hypodermis_morpholog	0.68904222
118	MP0000778_abnormal_nervous_system	0.68802894
119	MP0000653_abnormal_sex_gland	0.68647425
120	MP0001727_abnormal_embryo_implantation	0.68509999
121	MP0003136_yellow_coat_color	0.68447347
122	MP0002751_abnormal_autonomic_nervous	0.68442709
123	MP0005248_abnormal_Harderian_gland	0.68330156
124	MP0009250_abnormal_appendicular_skeleto	0.67348570
125	MP0005391_vision/eye_phenotype	0.64311497

Predicted human phenotypes

Rank	Gene Set	Z-score
1	Volvulus (HP:0002580)	3.90524196
2	Cortical dysplasia (HP:0002539)	3.86743152
3	Short 4th metacarpal (HP:0010044)	3.83260563
4	Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)	3.83260563
5	Increased nuchal translucency (HP:0010880)	3.65743347
6	Renal duplication (HP:0000075)	2.98892239
7	Colon cancer (HP:0003003)	2.97794608
8	Medulloblastoma (HP:0002885)	2.94965231
9	Abnormal number of incisors (HP:0011064)	2.93801140
10	Proximal placement of thumb (HP:0009623)	2.93466762
11	Abnormality of the 4th metacarpal (HP:0010012)	2.86948798
12	Deviation of the thumb (HP:0009603)	2.79116326
13	Selective tooth agenesis (HP:0001592)	2.77555765
14	Ependymoma (HP:0002888)	2.66216597
15	Hyperacusis (HP:0010780)	2.66067674
16	Chromsome breakage (HP:0040012)	2.61867056
17	Ectopic kidney (HP:0000086)	2.61443114
18	Multiple enchondromatosis (HP:0005701)	2.59181289
19	Spastic diplegia (HP:0001264)	2.59005046
20	Abnormality of the fingertips (HP:0001211)	2.46756979
21	Trigonocephaly (HP:0000243)	2.44448005
22	Absent radius (HP:0003974)	2.40233968
23	Abnormality of chromosome stability (HP:0003220)	2.38818897
24	Patellar aplasia (HP:0006443)	2.38690151
25	Long eyelashes (HP:0000527)	2.37871287
26	Birth length less than 3rd percentile (HP:0003561)	2.32441416
27	Hepatoblastoma (HP:0002884)	2.27701560
28	Aplasia/Hypoplasia of the patella (HP:0006498)	2.27094979
29	Abnormality of chromosome segregation (HP:0002916)	2.25825617
30	Absent forearm bone (HP:0003953)	2.25191491
31	Aplasia involving forearm bones (HP:0009822)	2.25191491
32	Chromosomal breakage induced by crosslinking agents (HP:0003221)	2.23362719
33	Atresia of the external auditory canal (HP:0000413)	2.23075835
34	Overriding aorta (HP:0002623)	2.18310177
35	11 pairs of ribs (HP:0000878)	2.18111327
36	Aplasia/Hypoplasia of the sternum (HP:0006714)	2.15900593
37	Abnormality of the labia minora (HP:0012880)	2.11982260
38	Cutis marmorata (HP:0000965)	2.09986113
39	Embryonal neoplasm (HP:0002898)	2.09732020
40	Elfin facies (HP:0004428)	2.08280700
41	Urethral obstruction (HP:0000796)	2.07886164
42	Obsessive-compulsive behavior (HP:0000722)	2.06232668
43	Meckel diverticulum (HP:0002245)	2.05242965
44	Astrocytoma (HP:0009592)	2.05054546
45	Abnormality of the astrocytes (HP:0100707)	2.05054546
46	Abnormal lung lobation (HP:0002101)	2.05023496
47	Reticulocytopenia (HP:0001896)	2.02678078
48	Renovascular hypertension (HP:0100817)	2.01902912
49	Deep philtrum (HP:0002002)	2.01444215
50	Skull defect (HP:0001362)	2.00730745
51	Myelodysplasia (HP:0002863)	2.00594511
52	Small intestinal stenosis (HP:0012848)	2.00502087
53	Duodenal stenosis (HP:0100867)	2.00502087
54	Progressive external ophthalmoplegia (HP:0000590)	2.00402738
55	Aplasia/Hypoplasia of the uvula (HP:0010293)	1.99464607
56	High anterior hairline (HP:0009890)	1.97452693
57	Abnormality of the ileum (HP:0001549)	1.96405035
58	Prominent nose (HP:0000448)	1.96223285
59	Broad palm (HP:0001169)	1.95898209
60	Abnormality of cochlea (HP:0000375)	1.95418287
61	Abnormality of the carotid arteries (HP:0005344)	1.95191274
62	High pitched voice (HP:0001620)	1.94949842
63	Horseshoe kidney (HP:0000085)	1.94714408
64	Facial hemangioma (HP:0000329)	1.94038763
65	Choanal atresia (HP:0000453)	1.93149377
66	Missing ribs (HP:0000921)	1.92088731
67	Broad thumb (HP:0011304)	1.89249209
68	Degeneration of anterior horn cells (HP:0002398)	1.88561642
69	Abnormality of the anterior horn cell (HP:0006802)	1.88561642
70	Pelvic girdle muscle weakness (HP:0003749)	1.88531192
71	Short middle phalanx of the 5th finger (HP:0004220)	1.88504263
72	Neoplasm of the colon (HP:0100273)	1.88331363
73	Pseudobulbar signs (HP:0002200)	1.88050343
74	Glioma (HP:0009733)	1.88046685
75	Shoulder girdle muscle weakness (HP:0003547)	1.87893734
76	Leiomyosarcoma (HP:0100243)	1.84580786
77	Uterine leiomyosarcoma (HP:0002891)	1.84580786
78	Optic nerve coloboma (HP:0000588)	1.84272522
79	Gastrointestinal carcinoma (HP:0002672)	1.84017760
80	Malignant gastrointestinal tract tumors (HP:0006749)	1.84017760
81	Spinal cord lesions (HP:0100561)	1.83066427
82	Syringomyelia (HP:0003396)	1.83066427
83	Anal stenosis (HP:0002025)	1.82899173
84	Sacral dimple (HP:0000960)	1.81221891
85	Abnormality of the preputium (HP:0100587)	1.80986108
86	Low anterior hairline (HP:0000294)	1.80333714
87	Basal cell carcinoma (HP:0002671)	1.80012631
88	Short 5th finger (HP:0009237)	1.78578196
89	Abnormality of the septum pellucidum (HP:0007375)	1.78231295
90	Uterine neoplasm (HP:0010784)	1.77696536
91	Broad phalanges of the hand (HP:0009768)	1.77550698
92	Radioulnar synostosis (HP:0002974)	1.76434978
93	Transitional cell carcinoma of the bladder (HP:0006740)	1.76106308
94	Pointed chin (HP:0000307)	1.75970998
95	Nephroblastoma (Wilms tumor) (HP:0002667)	1.75835303
96	Triphalangeal thumb (HP:0001199)	1.75113052
97	Skin tags (HP:0010609)	1.74824522
98	Overlapping toe (HP:0001845)	1.74544007
99	Acute myeloid leukemia (HP:0004808)	1.73637357
100	Abnormality of the duodenum (HP:0002246)	1.72926627
101	Hereditary nonpolyposis colorectal carcinoma (HP:0006716)	1.72722632
102	Supernumerary ribs (HP:0005815)	1.72187867
103	Increased density of long bones (HP:0006392)	1.72110317
104	Postnatal microcephaly (HP:0005484)	1.72106724
105	Insidious onset (HP:0003587)	1.71689325
106	Termporal pattern (HP:0011008)	1.71689325
107	Neoplasm of the small intestine (HP:0100833)	1.71659601
108	Cafe-au-lait spot (HP:0000957)	1.71497796
109	Rhabdomyosarcoma (HP:0002859)	1.71178677
110	Aplasia/Hypoplasia of the 5th finger (HP:0006262)	1.71166718
111	Abnormality of the intervertebral disk (HP:0005108)	1.70396722
112	Gonadotropin excess (HP:0000837)	1.70108932
113	Neoplasm of the pancreas (HP:0002894)	1.69679444
114	Acute lymphatic leukemia (HP:0006721)	1.68436304
115	Biliary tract neoplasm (HP:0100574)	1.67790767
116	Oligodactyly (HP:0012165)	1.67620467
117	Progressive muscle weakness (HP:0003323)	1.67348485
118	Insomnia (HP:0100785)	1.67108754
119	Neuroblastoma (HP:0003006)	1.66723667
120	Primitive neuroectodermal tumor (HP:0030065)	1.66723667
121	Neuroblastic tumors (HP:0004376)	1.66723667
122	Peripheral primitive neuroectodermal neoplasm (HP:0030067)	1.66723667
123	Embryonal renal neoplasm (HP:0011794)	1.65864291
124	Neoplasm of the oral cavity (HP:0100649)	1.65712100
125	Ovarian neoplasm (HP:0100615)	1.65630706
126	Abnormality of the hip-girdle musculature (HP:0001445)	1.65393993
127	Abnormality of the musculature of the pelvis (HP:0001469)	1.65393993
128	Neoplasm of the adrenal cortex (HP:0100641)	1.65384513
129	Preauricular skin tag (HP:0000384)	1.65346309
130	Esophageal atresia (HP:0002032)	1.63848082
131	Abnormality of the calcaneus (HP:0008364)	1.63024126
132	Truncal obesity (HP:0001956)	1.62922781
133	Abnormality of the diencephalon (HP:0010662)	1.62893816
134	Duplication of thumb phalanx (HP:0009942)	1.62647703
135	B lymphocytopenia (HP:0010976)	1.62483381
136	Abnormality of B cell number (HP:0010975)	1.62483381
137	Supernumerary bones of the axial skeleton (HP:0009144)	1.62452387
138	Septo-optic dysplasia (HP:0100842)	1.62251698
139	Facial cleft (HP:0002006)	1.61997633
140	Generalized hypotonia (HP:0001290)	1.61182377
141	Tracheoesophageal fistula (HP:0002575)	1.61021626
142	Morphological abnormality of the inner ear (HP:0011390)	1.60699773
143	Neoplasm of striated muscle (HP:0009728)	1.60031844
144	Omphalocele (HP:0001539)	1.59839297
145	Bowel diverticulosis (HP:0005222)	1.59676364
146	Sloping forehead (HP:0000340)	1.59456882
147	Neuroepithelial neoplasm (HP:0030063)	1.55678099

Predicted kinase interactions (KEA)

Rank	Gene Set	Z-score
1	CDC7	5.02826988
2	MKNK1	3.34480669
3	CDK12	2.93883975
4	NEK2	2.90774119
5	WEE1	2.80079528
6	BUB1	2.79511245
7	EEF2K	2.63915235
8	PASK	2.63288340
9	TSSK6	2.57909158
10	SRPK1	2.57115625
11	BRD4	2.44051214
12	MAP3K10	2.38496111
13	MKNK2	2.37917157
14	PBK	2.02433795
15	ATR	2.01540704
16	TNIK	1.94766188
17	ACVR1B	1.90890328
18	BRSK2	1.88853630
19	TAF1	1.84852607
20	TGFBR1	1.78379250
21	SMG1	1.75692272
22	NEK1	1.70436366
23	TTK	1.66383648
24	PLK3	1.66007186
25	ERBB3	1.61560840
26	RPS6KB2	1.59127473
27	EIF2AK1	1.58780925
28	PKN2	1.57914500
29	VRK2	1.55997362
30	CDK4	1.53459059
31	CCNB1	1.52705913
32	PLK1	1.47900717
33	AURKB	1.47029218
34	LATS2	1.44892474
35	TRIM28	1.43719267
36	CDK7	1.43449308
37	DYRK3	1.40729347
38	BRSK1	1.39488458
39	* CHEK1	1.35325863
40	PAK4	1.34892126
41	CDK6	1.33606749
42	RPS6KA4	1.25212159
43	TRIB3	1.21774312
44	TESK2	1.21661954
45	STK10	1.15376707
46	CHEK2	1.13086218
47	SIK3	1.12620178
48	ATM	1.11446517
49	CDK8	1.07809485
50	PLK4	1.05542324
51	ALK	1.05369923
52	FGFR1	1.01162948
53	CDK2	0.99193471
54	SCYL2	0.98385178
55	MST4	0.95910228
56	PTK6	0.94988823
57	ERBB4	0.92216942
58	EIF2AK2	0.90167025
59	VRK1	0.89431127
60	CDK1	0.88487936
61	CLK1	0.88363311
62	MAP3K8	0.86414777
63	KSR1	0.86366018
64	EPHB2	0.85507641
65	MAP4K1	0.77533477
66	LATS1	0.75453701
67	SIK2	0.75219472
68	STK38L	0.74970476
69	CDK3	0.74172654
70	MTOR	0.72960065
71	UHMK1	0.72917334
72	STK4	0.71916574
73	LRRK2	0.69021431
74	MELK	0.68499934
75	CSNK1A1L	0.66717439
76	BTK	0.65780134
77	STK3	0.64397409
78	PRKDC	0.60156078
79	NUAK1	0.59751265
80	PNCK	0.59331077
81	PDGFRA	0.58331023
82	CDK18	0.55380784
83	YES1	0.53476356
84	DMPK	0.52558434
85	PAK2	0.52381068
86	CDK15	0.50078360
87	ERBB2	0.49021192
88	CDK11A	0.48940128
89	MAPK14	0.47881313
90	FGFR3	0.47698508
91	CSNK2A2	0.47626750
92	CSNK1G3	0.47536740
93	CSF1R	0.45671077
94	FGFR2	0.45471032
95	ITK	0.45055886
96	AURKA	0.45036681
97	CAMK1G	0.44869578
98	FLT3	0.43823681
99	PDK2	0.43636610
100	DYRK1B	0.43070371
101	CDK14	0.42857896
102	EIF2AK3	0.42806191
103	AKT2	0.42235108
104	TTN	0.42199573
105	WNK3	0.41959066
106	CDK9	0.41270078
107	CSNK1D	0.41093734
108	CSNK1E	0.40284719
109	ILK	0.39085151
110	CSNK2A1	0.38414451
111	NME1	0.38253079
112	PLK2	0.37821554
113	BRAF	0.37298527
114	MAP3K9	0.36097909
115	AKT1	0.36010448
116	TESK1	0.35802456
117	CAMK1D	0.35687630
118	MAPK9	0.35476583
119	MAPK10	0.33789895
120	ZAK	0.33031109
121	GSK3B	0.32821384
122	STK24	0.32598393
123	BCR	0.32004720
124	FGFR4	0.31069060
125	STK16	0.30763213
126	CSNK1G1	0.26662269
127	LIMK1	0.26626471
128	ICK	0.26385807
129	MAPK1	0.26070271

Predicted pathways (KEGG)

Rank	Gene Set	Z-score
1	DNA replication_Homo sapiens_hsa03030	4.51747807
2	Spliceosome_Homo sapiens_hsa03040	3.91370314
3	Mismatch repair_Homo sapiens_hsa03430	3.61859936
4	Cell cycle_Homo sapiens_hsa04110	3.16874452
5	RNA transport_Homo sapiens_hsa03013	2.89570174
6	Base excision repair_Homo sapiens_hsa03410	2.83625047
7	mRNA surveillance pathway_Homo sapiens_hsa03015	2.62262145
8	Homologous recombination_Homo sapiens_hsa03440	2.50273448
9	Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008	2.48318730
10	Nucleotide excision repair_Homo sapiens_hsa03420	2.39393105
11	Non-homologous end-joining_Homo sapiens_hsa03450	2.24482777
12	Fanconi anemia pathway_Homo sapiens_hsa03460	1.97512154
13	RNA degradation_Homo sapiens_hsa03018	1.94722365
14	Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970	1.84355393
15	One carbon pool by folate_Homo sapiens_hsa00670	1.68727709
16	Biosynthesis of amino acids_Homo sapiens_hsa01230	1.58872435
17	Citrate cycle (TCA cycle)_Homo sapiens_hsa00020	1.57446060
18	Cysteine and methionine metabolism_Homo sapiens_hsa00270	1.56428408
19	Terpenoid backbone biosynthesis_Homo sapiens_hsa00900	1.55747507
20	Basal cell carcinoma_Homo sapiens_hsa05217	1.52974500
21	Basal transcription factors_Homo sapiens_hsa03022	1.47886044
22	Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914	1.44565736
23	p53 signaling pathway_Homo sapiens_hsa04115	1.43058151
24	RNA polymerase_Homo sapiens_hsa03020	1.39797196
25	MicroRNAs in cancer_Homo sapiens_hsa05206	1.38386576
26	Ubiquitin mediated proteolysis_Homo sapiens_hsa04120	1.36457690
27	HTLV-I infection_Homo sapiens_hsa05166	1.34225889
28	Pyrimidine metabolism_Homo sapiens_hsa00240	1.34171828
29	Antigen processing and presentation_Homo sapiens_hsa04612	1.33578372
30	2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210	1.33262153
31	Ribosome_Homo sapiens_hsa03010	1.33039650
32	Notch signaling pathway_Homo sapiens_hsa04330	1.32769616
33	Oocyte meiosis_Homo sapiens_hsa04114	1.32401948
34	Colorectal cancer_Homo sapiens_hsa05210	1.32242124
35	Chronic myeloid leukemia_Homo sapiens_hsa05220	1.28052659
36	Primary immunodeficiency_Homo sapiens_hsa05340	1.26645841
37	Steroid biosynthesis_Homo sapiens_hsa00100	1.25026319
38	Herpes simplex infection_Homo sapiens_hsa05168	1.23348506
39	Pyruvate metabolism_Homo sapiens_hsa00620	1.21864180
40	Epstein-Barr virus infection_Homo sapiens_hsa05169	1.20934997
41	Viral carcinogenesis_Homo sapiens_hsa05203	1.16118702
42	Pathogenic Escherichia coli infection_Homo sapiens_hsa05130	1.15946688
43	Vitamin B6 metabolism_Homo sapiens_hsa00750	1.13935195
44	Small cell lung cancer_Homo sapiens_hsa05222	1.11671018
45	Carbon metabolism_Homo sapiens_hsa01200	1.11343028
46	Hippo signaling pathway_Homo sapiens_hsa04390	1.09744095
47	Proteasome_Homo sapiens_hsa03050	1.09500322
48	Transcriptional misregulation in cancer_Homo sapiens_hsa05202	1.07153400
49	Hedgehog signaling pathway_Homo sapiens_hsa04340	1.01782211
50	Thyroid cancer_Homo sapiens_hsa05216	0.95929026
51	Lysine degradation_Homo sapiens_hsa00310	0.95183715
52	Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630	0.94708080
53	Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550	0.93482973
54	Viral myocarditis_Homo sapiens_hsa05416	0.93285156
55	Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010	0.92321595
56	Propanoate metabolism_Homo sapiens_hsa00640	0.91087695
57	Non-small cell lung cancer_Homo sapiens_hsa05223	0.89477477
58	Glycine, serine and threonine metabolism_Homo sapiens_hsa00260	0.89465477
59	Wnt signaling pathway_Homo sapiens_hsa04310	0.84793829
60	Bacterial invasion of epithelial cells_Homo sapiens_hsa05100	0.84616103
61	Pancreatic cancer_Homo sapiens_hsa05212	0.83940543
62	Hepatitis B_Homo sapiens_hsa05161	0.83131084
63	Endometrial cancer_Homo sapiens_hsa05213	0.81195391
64	N-Glycan biosynthesis_Homo sapiens_hsa00510	0.79831427
65	Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250	0.79629170
66	TGF-beta signaling pathway_Homo sapiens_hsa04350	0.78563569
67	Adherens junction_Homo sapiens_hsa04520	0.76595383
68	Pathways in cancer_Homo sapiens_hsa05200	0.75369964
69	T cell receptor signaling pathway_Homo sapiens_hsa04660	0.75263413
70	Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524	0.74971550
71	Prostate cancer_Homo sapiens_hsa05215	0.74042482
72	Proteoglycans in cancer_Homo sapiens_hsa05205	0.73068990
73	B cell receptor signaling pathway_Homo sapiens_hsa04662	0.68422641
74	Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040	0.67886777
75	Pentose phosphate pathway_Homo sapiens_hsa00030	0.67398485
76	Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072	0.67069373
77	Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141	0.64455438
78	mTOR signaling pathway_Homo sapiens_hsa04150	0.63463586
79	Fc epsilon RI signaling pathway_Homo sapiens_hsa04664	0.62376874
80	Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666	0.62178627
81	Neurotrophin signaling pathway_Homo sapiens_hsa04722	0.61887728
82	Shigellosis_Homo sapiens_hsa05131	0.61857854
83	Thyroid hormone signaling pathway_Homo sapiens_hsa04919	0.61022945
84	Purine metabolism_Homo sapiens_hsa00230	0.60645767
85	Acute myeloid leukemia_Homo sapiens_hsa05221	0.60531686
86	Measles_Homo sapiens_hsa05162	0.59071375
87	Central carbon metabolism in cancer_Homo sapiens_hsa05230	0.56901531
88	Bladder cancer_Homo sapiens_hsa05219	0.55192281
89	Leukocyte transendothelial migration_Homo sapiens_hsa04670	0.53309709
90	Folate biosynthesis_Homo sapiens_hsa00790	0.52878347
91	Glioma_Homo sapiens_hsa05214	0.50963939
92	Apoptosis_Homo sapiens_hsa04210	0.50365494
93	FoxO signaling pathway_Homo sapiens_hsa04068	0.48637718
94	Legionellosis_Homo sapiens_hsa05134	0.48593762
95	Systemic lupus erythematosus_Homo sapiens_hsa05322	0.47732146
96	Renal cell carcinoma_Homo sapiens_hsa05211	0.47616011
97	Fatty acid metabolism_Homo sapiens_hsa01212	0.44931907
98	Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280	0.44375916
99	Other types of O-glycan biosynthesis_Homo sapiens_hsa00514	0.44099327
100	Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650	0.43939612
101	Focal adhesion_Homo sapiens_hsa04510	0.42598006
102	Alcoholism_Homo sapiens_hsa05034	0.42405622
103	Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400	0.42002093
104	NF-kappa B signaling pathway_Homo sapiens_hsa04064	0.41135724
105	Influenza A_Homo sapiens_hsa05164	0.40801170
106	Platelet activation_Homo sapiens_hsa04611	0.37810010
107	Hematopoietic cell lineage_Homo sapiens_hsa04640	0.37165660
108	Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770	0.36955384
109	PI3K-Akt signaling pathway_Homo sapiens_hsa04151	0.36812566
110	NOD-like receptor signaling pathway_Homo sapiens_hsa04621	0.35632945
111	AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933	0.35513820
112	HIF-1 signaling pathway_Homo sapiens_hsa04066	0.33249780
113	Toxoplasmosis_Homo sapiens_hsa05145	0.32989263
114	Melanoma_Homo sapiens_hsa05218	0.32614212
115	Fatty acid elongation_Homo sapiens_hsa00062	0.32448256
116	Protein export_Homo sapiens_hsa03060	0.32110612
117	Selenocompound metabolism_Homo sapiens_hsa00450	0.30936080
118	Longevity regulating pathway - multiple species_Homo sapiens_hsa04213	0.30655063
119	Axon guidance_Homo sapiens_hsa04360	0.29953149
120	Melanogenesis_Homo sapiens_hsa04916	0.28578383
121	Leishmaniasis_Homo sapiens_hsa05140	0.28241086
122	Tight junction_Homo sapiens_hsa04530	0.28220099
123	Intestinal immune network for IgA production_Homo sapiens_hsa04672	0.26984025
124	Regulation of actin cytoskeleton_Homo sapiens_hsa04810	0.26796757
125	Longevity regulating pathway - mammal_Homo sapiens_hsa04211	0.23233333
126	Arginine and proline metabolism_Homo sapiens_hsa00330	0.20051824
127	ErbB signaling pathway_Homo sapiens_hsa04012	0.17766373
128	AMPK signaling pathway_Homo sapiens_hsa04152	0.17186860
129	Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534	0.17125778
130	Estrogen signaling pathway_Homo sapiens_hsa04915	0.16514769
131	Insulin signaling pathway_Homo sapiens_hsa04910	0.16469540
132	Glucagon signaling pathway_Homo sapiens_hsa04922	0.14344544
133	Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520	0.14176095
134	Fructose and mannose metabolism_Homo sapiens_hsa00051	0.13930035

HNRNPA2B1

Functional Annotation Prediction

Predicted biological processes (GO)

Predicted upstream transcription factors (ChEA)

Predicted mouse phenotypes (MGI)

Predicted human phenotypes

Predicted kinase interactions (KEA)

Predicted pathways (KEGG)

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