Rank | Gene Set | Z-score |
---|---|---|
1 | mitotic sister chromatid cohesion (GO:0007064) | 5.91541451 |
2 | DNA unwinding involved in DNA replication (GO:0006268) | 5.02111935 |
3 | pre-miRNA processing (GO:0031054) | 5.01126635 |
4 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.90671536 |
5 | nuclear pore organization (GO:0006999) | 4.66753344 |
6 | nuclear pore complex assembly (GO:0051292) | 4.62437678 |
7 | protein localization to kinetochore (GO:0034501) | 4.50979361 |
8 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 4.45707965 |
9 | negative regulation of RNA splicing (GO:0033119) | 4.23617635 |
10 | sister chromatid segregation (GO:0000819) | 4.20166466 |
11 | regulation of RNA export from nucleus (GO:0046831) | 4.08531858 |
12 | RNA stabilization (GO:0043489) | 4.03870915 |
13 | mRNA stabilization (GO:0048255) | 4.03870915 |
14 | establishment of integrated proviral latency (GO:0075713) | 4.02151897 |
15 | glucocorticoid receptor signaling pathway (GO:0042921) | 4.00018222 |
16 | regulation of sister chromatid cohesion (GO:0007063) | 3.99384822 |
17 | negative regulation of mRNA processing (GO:0050686) | 3.97500187 |
18 | formation of translation preinitiation complex (GO:0001731) | 3.95284961 |
19 | heterochromatin organization (GO:0070828) | 3.87199898 |
20 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.86785561 |
21 | negative regulation of histone methylation (GO:0031061) | 3.79482343 |
22 | regulation of DNA endoreduplication (GO:0032875) | 3.76162806 |
23 | DNA strand elongation (GO:0022616) | 3.74540729 |
24 | protein localization to chromosome, centromeric region (GO:0071459) | 3.74163575 |
25 | negative regulation of mRNA metabolic process (GO:1903312) | 3.73351906 |
26 | kinetochore organization (GO:0051383) | 3.73284618 |
27 | mitotic chromosome condensation (GO:0007076) | 3.72165381 |
28 | alternative mRNA splicing, via spliceosome (GO:0000380) | 3.67980682 |
29 | mitotic sister chromatid segregation (GO:0000070) | 3.66316002 |
30 | DNA replication initiation (GO:0006270) | 3.64386044 |
31 | mitotic nuclear envelope disassembly (GO:0007077) | 3.60695094 |
32 | protein complex localization (GO:0031503) | 3.60537880 |
33 | cellular protein complex localization (GO:0034629) | 3.60466702 |
34 | DNA topological change (GO:0006265) | 3.54772133 |
35 | DNA duplex unwinding (GO:0032508) | 3.50742029 |
36 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.49556014 |
37 | DNA geometric change (GO:0032392) | 3.48456188 |
38 | nuclear envelope disassembly (GO:0051081) | 3.46199371 |
39 | membrane disassembly (GO:0030397) | 3.46199371 |
40 | regulation of histone H3-K27 methylation (GO:0061085) | 3.38545339 |
41 | regulation of mRNA stability (GO:0043488) | 3.37382800 |
42 | mitotic metaphase plate congression (GO:0007080) | 3.34577540 |
43 | peptidyl-lysine dimethylation (GO:0018027) | 3.33355300 |
44 | dosage compensation (GO:0007549) | 3.32169761 |
45 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.28340776 |
46 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.28340776 |
47 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.28340776 |
48 | pore complex assembly (GO:0046931) | 3.25686646 |
49 | regulation of spindle organization (GO:0090224) | 3.24670192 |
50 | positive regulation of chromosome segregation (GO:0051984) | 3.21384604 |
51 | regulation of nucleobase-containing compound transport (GO:0032239) | 3.17256141 |
52 | corticosteroid receptor signaling pathway (GO:0031958) | 3.15164311 |
53 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.13331116 |
54 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 3.12606153 |
55 | protein export from nucleus (GO:0006611) | 3.12550265 |
56 | cytoplasmic mRNA processing body assembly (GO:0033962) | 3.12277155 |
57 | metaphase plate congression (GO:0051310) | 3.11814520 |
58 | regulation of RNA stability (GO:0043487) | 3.11631946 |
59 | protein localization to chromosome (GO:0034502) | 3.09578851 |
60 | ribosomal small subunit biogenesis (GO:0042274) | 3.09346731 |
61 | regulation of histone H3-K9 methylation (GO:0051570) | 3.09306779 |
62 | IMP biosynthetic process (GO:0006188) | 3.08437016 |
63 | DNA packaging (GO:0006323) | 3.08110814 |
64 | regulation of mitotic spindle organization (GO:0060236) | 3.05610161 |
65 | regulation of centriole replication (GO:0046599) | 3.05396142 |
66 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.05380548 |
67 | NLS-bearing protein import into nucleus (GO:0006607) | 3.04115824 |
68 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.03613478 |
69 | positive regulation of cell cycle checkpoint (GO:1901978) | 3.02799232 |
70 | chromatin assembly (GO:0031497) | 3.02457333 |
71 | * mRNA splicing, via spliceosome (GO:0000398) | 3.02126830 |
72 | * RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) | 3.02126830 |
73 | paraxial mesoderm development (GO:0048339) | 3.01784277 |
74 | ATP-dependent chromatin remodeling (GO:0043044) | 3.01403667 |
75 | * RNA splicing, via transesterification reactions (GO:0000375) | 2.99875994 |
76 | negative regulation of DNA repair (GO:0045738) | 2.99068891 |
77 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.97815143 |
78 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.97761816 |
79 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.97761816 |
80 | hippo signaling (GO:0035329) | 2.95580398 |
81 | IMP metabolic process (GO:0046040) | 2.92415030 |
82 | V(D)J recombination (GO:0033151) | 2.91765290 |
83 | chromatin assembly or disassembly (GO:0006333) | 2.91402159 |
84 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 2.89910904 |
85 | mRNA splice site selection (GO:0006376) | 2.89681369 |
86 | regulation of translational fidelity (GO:0006450) | 2.86535046 |
87 | regulation of NFAT protein import into nucleus (GO:0051532) | 2.86457640 |
88 | histone H2B ubiquitination (GO:0033523) | 2.85660822 |
89 | DNA conformation change (GO:0071103) | 2.85345176 |
90 | DNA replication checkpoint (GO:0000076) | 2.85264250 |
91 | regulation of chromosome segregation (GO:0051983) | 2.85120873 |
92 | kinetochore assembly (GO:0051382) | 2.84720056 |
93 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 2.84518923 |
94 | protein-DNA complex disassembly (GO:0032986) | 2.80749265 |
95 | nucleosome disassembly (GO:0006337) | 2.80749265 |
96 | peptidyl-arginine methylation (GO:0018216) | 2.79441506 |
97 | peptidyl-arginine N-methylation (GO:0035246) | 2.79441506 |
98 | regulation of centrosome cycle (GO:0046605) | 2.78614233 |
99 | RNA transport (GO:0050658) | 2.77076864 |
100 | establishment of RNA localization (GO:0051236) | 2.77076864 |
101 | nucleic acid transport (GO:0050657) | 2.77076864 |
102 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.77034640 |
103 | DNA replication-independent nucleosome organization (GO:0034724) | 2.77034640 |
104 | translesion synthesis (GO:0019985) | 2.75860162 |
105 | cellular response to epidermal growth factor stimulus (GO:0071364) | 2.75242295 |
106 | nuclear envelope organization (GO:0006998) | 2.74740238 |
107 | maturation of SSU-rRNA (GO:0030490) | 2.73935571 |
108 | establishment of chromosome localization (GO:0051303) | 2.73537608 |
109 | mitotic recombination (GO:0006312) | 2.73475237 |
110 | histone H2A monoubiquitination (GO:0035518) | 2.73047933 |
111 | positive regulation of RNA splicing (GO:0033120) | 2.72965236 |
112 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 2.72517613 |
113 | DNA synthesis involved in DNA repair (GO:0000731) | 2.71850844 |
114 | attachment of spindle microtubules to kinetochore (GO:0008608) | 2.71620198 |
115 | peptidyl-arginine omega-N-methylation (GO:0035247) | 2.71102481 |
116 | viral transcription (GO:0019083) | 2.70818690 |
117 | mRNA transport (GO:0051028) | 2.70649146 |
118 | regulation of telomere maintenance via telomerase (GO:0032210) | 2.70493338 |
119 | termination of RNA polymerase II transcription (GO:0006369) | 2.69336110 |
120 | regulation of stem cell maintenance (GO:2000036) | 2.69123313 |
121 | spindle checkpoint (GO:0031577) | 2.67771465 |
122 | RNA export from nucleus (GO:0006405) | 2.67505310 |
123 | chromosome segregation (GO:0007059) | 2.67430433 |
124 | spindle assembly checkpoint (GO:0071173) | 2.67164114 |
125 | chromosome condensation (GO:0030261) | 2.67104206 |
126 | establishment of viral latency (GO:0019043) | 2.66578210 |
127 | convergent extension (GO:0060026) | 2.65298391 |
128 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 2.64795494 |
129 | translational termination (GO:0006415) | 2.64624545 |
130 | regulation of histone methylation (GO:0031060) | 2.64529520 |
131 | negative regulation of histone acetylation (GO:0035067) | 2.61449337 |
132 | positive regulation of gene expression, epigenetic (GO:0045815) | 2.60756007 |
133 | mitotic spindle checkpoint (GO:0071174) | 2.59872759 |
134 | regulation of centrosome duplication (GO:0010824) | 2.59400686 |
135 | mitotic spindle assembly checkpoint (GO:0007094) | 2.59027444 |
136 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.58283401 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 6.80704746 |
2 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 4.47682637 |
3 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.45422710 |
4 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.54617061 |
5 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.33486722 |
6 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 3.26211340 |
7 | MYC_22102868_ChIP-Seq_BL_Human | 3.11883364 |
8 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.72452415 |
9 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.72047251 |
10 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.70632694 |
11 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.62519433 |
12 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 2.61286860 |
13 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.55277813 |
14 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.50610162 |
15 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.27020559 |
16 | E2F7_22180533_ChIP-Seq_HELA_Human | 10.3697412 |
17 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.98690902 |
18 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.94039640 |
19 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.89221470 |
20 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.86791070 |
21 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.83352350 |
22 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.67788709 |
23 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.67595629 |
24 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.66986068 |
25 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.64471375 |
26 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.64127387 |
27 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.62843485 |
28 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.57744918 |
29 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.57568117 |
30 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.52146282 |
31 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.51562550 |
32 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.49951462 |
33 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.49346918 |
34 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.48782978 |
35 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.48427578 |
36 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.46141370 |
37 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.43862520 |
38 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.43731822 |
39 | * TTF2_22483619_ChIP-Seq_HELA_Human | 1.43041709 |
40 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.42809680 |
41 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.41364148 |
42 | * FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 1.41215842 |
43 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.40750904 |
44 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.37639524 |
45 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.37093581 |
46 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.35203868 |
47 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.34458987 |
48 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.34317489 |
49 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.29956552 |
50 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.29662203 |
51 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.27164087 |
52 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.26026084 |
53 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.24719302 |
54 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.24016295 |
55 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.23716457 |
56 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.22788211 |
57 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.22786568 |
58 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.22580286 |
59 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.22281451 |
60 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.20073944 |
61 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.20010174 |
62 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.18577357 |
63 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.17162516 |
64 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.14349822 |
65 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.11646702 |
66 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.10437518 |
67 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.09718474 |
68 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.09263192 |
69 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.09093825 |
70 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.08602967 |
71 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.07648893 |
72 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.07319577 |
73 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.06063585 |
74 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.06002670 |
75 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.05707562 |
76 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.04130423 |
77 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.03973097 |
78 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.03771708 |
79 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.03233809 |
80 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.02566615 |
81 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.01909883 |
82 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.01117446 |
83 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.00046543 |
84 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.97348755 |
85 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.97348755 |
86 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.97348755 |
87 | * UTX_26944678_Chip-Seq_JUKART_Human | 0.97031544 |
88 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 0.96337986 |
89 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.95969969 |
90 | * CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.95897729 |
91 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.94728927 |
92 | * FOXP3_21729870_ChIP-Seq_TREG_Human | 0.93402185 |
93 | KDM2B_26808549_Chip-Seq_K562_Human | 0.93089028 |
94 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.92129650 |
95 | TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 0.90901451 |
96 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 0.89881455 |
97 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 0.89670611 |
98 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.89444557 |
99 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 0.89214381 |
100 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.88986722 |
101 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 0.88680630 |
102 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.88274851 |
103 | VDR_23849224_ChIP-Seq_CD4+_Human | 0.87460679 |
104 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 0.86626846 |
105 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.86479398 |
106 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.86227906 |
107 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.85826669 |
108 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.85515754 |
109 | POU5F1_18347094_ChIP-ChIP_MESCs_Mouse | 0.85450497 |
110 | RACK7_27058665_Chip-Seq_MCF-7_Human | 0.85201924 |
111 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.84928315 |
112 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.84565846 |
113 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.84271659 |
114 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 0.84031720 |
115 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.83939883 |
116 | KAP1_27257070_Chip-Seq_ESCs_Mouse | 0.83345950 |
117 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 0.82730908 |
118 | * NCOR1_26117541_ChIP-Seq_K562_Human | 0.82557087 |
119 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.82110189 |
120 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 0.82060549 |
121 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 0.79221468 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003123_paternal_imprinting | 3.19600411 |
2 | MP0003693_abnormal_embryo_hatching | 2.94059557 |
3 | MP0003111_abnormal_nucleus_morphology | 2.90720553 |
4 | MP0010094_abnormal_chromosome_stability | 2.87579616 |
5 | MP0004957_abnormal_blastocyst_morpholog | 2.86135279 |
6 | MP0005076_abnormal_cell_differentiation | 2.77190950 |
7 | MP0010352_gastrointestinal_tract_polyps | 2.68498499 |
8 | MP0000537_abnormal_urethra_morphology | 2.62309626 |
9 | MP0003121_genomic_imprinting | 2.53336968 |
10 | MP0003077_abnormal_cell_cycle | 2.52241928 |
11 | MP0000566_synostosis | 2.50850224 |
12 | MP0008057_abnormal_DNA_replication | 2.41227471 |
13 | MP0003705_abnormal_hypodermis_morpholog | 2.32400230 |
14 | MP0009053_abnormal_anal_canal | 2.31844580 |
15 | MP0001730_embryonic_growth_arrest | 2.19672495 |
16 | MP0002009_preneoplasia | 2.12899552 |
17 | MP0010234_abnormal_vibrissa_follicle | 2.10959324 |
18 | MP0002084_abnormal_developmental_patter | 2.08794472 |
19 | MP0003890_abnormal_embryonic-extraembry | 2.08502799 |
20 | MP0004197_abnormal_fetal_growth/weight/ | 2.04625674 |
21 | MP0010030_abnormal_orbit_morphology | 1.98856893 |
22 | MP0003122_maternal_imprinting | 1.98496522 |
23 | MP0000350_abnormal_cell_proliferation | 1.97317764 |
24 | MP0002085_abnormal_embryonic_tissue | 1.88324998 |
25 | MP0001672_abnormal_embryogenesis/_devel | 1.87118730 |
26 | MP0005380_embryogenesis_phenotype | 1.87118730 |
27 | MP0003567_abnormal_fetal_cardiomyocyte | 1.85210959 |
28 | MP0004185_abnormal_adipocyte_glucose | 1.83374267 |
29 | MP0001697_abnormal_embryo_size | 1.81859281 |
30 | MP0005187_abnormal_penis_morphology | 1.79312794 |
31 | MP0003984_embryonic_growth_retardation | 1.75652435 |
32 | MP0002088_abnormal_embryonic_growth/wei | 1.75248349 |
33 | MP0002086_abnormal_extraembryonic_tissu | 1.72665397 |
34 | MP0001293_anophthalmia | 1.69020419 |
35 | MP0010307_abnormal_tumor_latency | 1.67210047 |
36 | MP0003119_abnormal_digestive_system | 1.67016256 |
37 | MP0008932_abnormal_embryonic_tissue | 1.66607535 |
38 | MP0000569_abnormal_digit_pigmentation | 1.62926173 |
39 | MP0009703_decreased_birth_body | 1.62774355 |
40 | MP0009672_abnormal_birth_weight | 1.62032574 |
41 | MP0008007_abnormal_cellular_replicative | 1.58539965 |
42 | MP0003385_abnormal_body_wall | 1.54182346 |
43 | MP0003787_abnormal_imprinting | 1.52997272 |
44 | MP0000428_abnormal_craniofacial_morphol | 1.51019951 |
45 | MP0003935_abnormal_craniofacial_develop | 1.49332177 |
46 | MP0003937_abnormal_limbs/digits/tail_de | 1.49188923 |
47 | MP0002080_prenatal_lethality | 1.48252006 |
48 | MP0004808_abnormal_hematopoietic_stem | 1.39548361 |
49 | MP0002396_abnormal_hematopoietic_system | 1.37586109 |
50 | MP0000733_abnormal_muscle_development | 1.36966844 |
51 | MP0003115_abnormal_respiratory_system | 1.33982561 |
52 | MP0001346_abnormal_lacrimal_gland | 1.31273935 |
53 | MP0005409_darkened_coat_color | 1.29226289 |
54 | MP0001849_ear_inflammation | 1.28146932 |
55 | MP0006054_spinal_hemorrhage | 1.26246381 |
56 | MP0003755_abnormal_palate_morphology | 1.23509271 |
57 | MP0003283_abnormal_digestive_organ | 1.21766500 |
58 | MP0002877_abnormal_melanocyte_morpholog | 1.21497003 |
59 | MP0009379_abnormal_foot_pigmentation | 1.20826478 |
60 | MP0005248_abnormal_Harderian_gland | 1.19851764 |
61 | MP0003942_abnormal_urinary_system | 1.19493244 |
62 | MP0000432_abnormal_head_morphology | 1.18768160 |
63 | MP0008058_abnormal_DNA_repair | 1.18373996 |
64 | MP0002092_abnormal_eye_morphology | 1.16815397 |
65 | MP0002697_abnormal_eye_size | 1.14949875 |
66 | MP0002796_impaired_skin_barrier | 1.14439030 |
67 | MP0003861_abnormal_nervous_system | 1.13348521 |
68 | MP0002925_abnormal_cardiovascular_devel | 1.11012199 |
69 | MP0009278_abnormal_bone_marrow | 1.10647013 |
70 | MP0000534_abnormal_ureter_morphology | 1.10297181 |
71 | MP0005623_abnormal_meninges_morphology | 1.10108284 |
72 | MP0002249_abnormal_larynx_morphology | 1.10107469 |
73 | MP0002089_abnormal_postnatal_growth/wei | 1.09353262 |
74 | MP0001286_abnormal_eye_development | 1.07379584 |
75 | MP0010678_abnormal_skin_adnexa | 1.07113810 |
76 | MP0003300_gastrointestinal_ulcer | 1.06931623 |
77 | MP0002938_white_spotting | 1.06915948 |
78 | MP0005367_renal/urinary_system_phenotyp | 1.06567107 |
79 | MP0000516_abnormal_urinary_system | 1.06567107 |
80 | MP0009697_abnormal_copulation | 1.04062738 |
81 | MP0009250_abnormal_appendicular_skeleto | 1.03701723 |
82 | MP0002932_abnormal_joint_morphology | 1.03593548 |
83 | MP0000678_abnormal_parathyroid_gland | 0.99620082 |
84 | MP0008877_abnormal_DNA_methylation | 0.99132336 |
85 | MP0002116_abnormal_craniofacial_bone | 0.98019604 |
86 | MP0000049_abnormal_middle_ear | 0.97246329 |
87 | MP0002653_abnormal_ependyma_morphology | 0.96850275 |
88 | MP0002111_abnormal_tail_morphology | 0.96185838 |
89 | MP0003315_abnormal_perineum_morphology | 0.95896308 |
90 | MP0004264_abnormal_extraembryonic_tissu | 0.95614827 |
91 | MP0003941_abnormal_skin_development | 0.93903842 |
92 | MP0002233_abnormal_nose_morphology | 0.93838599 |
93 | MP0003943_abnormal_hepatobiliary_system | 0.93553091 |
94 | MP0000703_abnormal_thymus_morphology | 0.93388168 |
95 | MP0010630_abnormal_cardiac_muscle | 0.93326602 |
96 | MP0005501_abnormal_skin_physiology | 0.93221919 |
97 | MP0008789_abnormal_olfactory_epithelium | 0.91928339 |
98 | MP0001188_hyperpigmentation | 0.91627953 |
99 | MP0004858_abnormal_nervous_system | 0.90355474 |
100 | MP0000490_abnormal_crypts_of | 0.89373600 |
101 | MP0005621_abnormal_cell_physiology | 0.89254604 |
102 | MP0002081_perinatal_lethality | 0.87873176 |
103 | MP0000383_abnormal_hair_follicle | 0.86790099 |
104 | MP0004233_abnormal_muscle_weight | 0.86258153 |
105 | MP0006292_abnormal_olfactory_placode | 0.84136636 |
106 | MP0001915_intracranial_hemorrhage | 0.83628096 |
107 | MP0000313_abnormal_cell_death | 0.83198822 |
108 | MP0005666_abnormal_adipose_tissue | 0.83159062 |
109 | MP0003303_peritoneal_inflammation | 0.83021038 |
110 | MP0002114_abnormal_axial_skeleton | 0.82334685 |
111 | MP0000579_abnormal_nail_morphology | 0.80001627 |
112 | MP0002282_abnormal_trachea_morphology | 0.79036763 |
113 | MP0003453_abnormal_keratinocyte_physiol | 0.78205453 |
114 | MP0000266_abnormal_heart_morphology | 0.76684590 |
115 | MP0008770_decreased_survivor_rate | 0.76338014 |
116 | MP0001784_abnormal_fluid_regulation | 0.75547546 |
117 | MP0001348_abnormal_lacrimal_gland | 0.74516661 |
118 | MP0005384_cellular_phenotype | 0.74131378 |
119 | MP0003566_abnormal_cell_adhesion | 0.73926852 |
120 | MP0002234_abnormal_pharynx_morphology | 0.73895167 |
121 | MP0000762_abnormal_tongue_morphology | 0.72338523 |
122 | MP0002019_abnormal_tumor_incidence | 0.70711018 |
123 | MP0003938_abnormal_ear_development | 0.70169037 |
124 | MP0002109_abnormal_limb_morphology | 0.69723884 |
125 | MP0001340_abnormal_eyelid_morphology | 0.68897762 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Volvulus (HP:0002580) | 4.16271262 |
2 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 4.08314659 |
3 | Short 4th metacarpal (HP:0010044) | 4.08314659 |
4 | Increased nuchal translucency (HP:0010880) | 3.42899934 |
5 | Colon cancer (HP:0003003) | 3.34740658 |
6 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.15754112 |
7 | Chromsome breakage (HP:0040012) | 3.13115760 |
8 | Abnormality of the 4th metacarpal (HP:0010012) | 3.12573589 |
9 | Renal duplication (HP:0000075) | 2.97067746 |
10 | Medulloblastoma (HP:0002885) | 2.79045482 |
11 | Proximal placement of thumb (HP:0009623) | 2.77095472 |
12 | Rectal prolapse (HP:0002035) | 2.74994523 |
13 | Ependymoma (HP:0002888) | 2.72397237 |
14 | Cortical dysplasia (HP:0002539) | 2.69807222 |
15 | Overlapping toe (HP:0001845) | 2.68460312 |
16 | Deviation of the thumb (HP:0009603) | 2.68079220 |
17 | Insomnia (HP:0100785) | 2.67678259 |
18 | Hyperacusis (HP:0010780) | 2.66944539 |
19 | Long eyelashes (HP:0000527) | 2.61381321 |
20 | Macroorchidism (HP:0000053) | 2.54227764 |
21 | Abnormality of the astrocytes (HP:0100707) | 2.53452526 |
22 | Astrocytoma (HP:0009592) | 2.53452526 |
23 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.52926070 |
24 | Atresia of the external auditory canal (HP:0000413) | 2.52075590 |
25 | Abnormality of the fingertips (HP:0001211) | 2.51300429 |
26 | High anterior hairline (HP:0009890) | 2.40860943 |
27 | Rhabdomyosarcoma (HP:0002859) | 2.37669192 |
28 | Birth length less than 3rd percentile (HP:0003561) | 2.36925627 |
29 | Embryonal renal neoplasm (HP:0011794) | 2.34434389 |
30 | Abnormal number of incisors (HP:0011064) | 2.34144889 |
31 | Shallow orbits (HP:0000586) | 2.33365603 |
32 | Obsessive-compulsive behavior (HP:0000722) | 2.33273803 |
33 | Supernumerary ribs (HP:0005815) | 2.30343007 |
34 | Abnormality of the labia minora (HP:0012880) | 2.28911356 |
35 | Neoplasm of striated muscle (HP:0009728) | 2.27148839 |
36 | Ankyloglossia (HP:0010296) | 2.26202984 |
37 | Malignant gastrointestinal tract tumors (HP:0006749) | 2.26194639 |
38 | Gastrointestinal carcinoma (HP:0002672) | 2.26194639 |
39 | Acute lymphatic leukemia (HP:0006721) | 2.25749816 |
40 | Broad thumb (HP:0011304) | 2.23190114 |
41 | Biliary tract neoplasm (HP:0100574) | 2.23101291 |
42 | Abnormality of cochlea (HP:0000375) | 2.22733768 |
43 | Pseudobulbar signs (HP:0002200) | 2.19368935 |
44 | Selective tooth agenesis (HP:0001592) | 2.18944926 |
45 | Renovascular hypertension (HP:0100817) | 2.17660162 |
46 | Disproportionate tall stature (HP:0001519) | 2.17524933 |
47 | Neoplasm of the oral cavity (HP:0100649) | 2.14816251 |
48 | Elfin facies (HP:0004428) | 2.14182661 |
49 | Trigonocephaly (HP:0000243) | 2.13191685 |
50 | Cutis marmorata (HP:0000965) | 2.12936487 |
51 | Subacute progressive viral hepatitis (HP:0006572) | 2.12847834 |
52 | Facial hemangioma (HP:0000329) | 2.11508022 |
53 | Glioma (HP:0009733) | 2.10439439 |
54 | Arnold-Chiari malformation (HP:0002308) | 2.07460381 |
55 | Reticulocytopenia (HP:0001896) | 2.07305326 |
56 | Skin tags (HP:0010609) | 2.07291957 |
57 | Overriding aorta (HP:0002623) | 2.05057353 |
58 | Sacral dimple (HP:0000960) | 2.04975880 |
59 | Supernumerary bones of the axial skeleton (HP:0009144) | 2.04778074 |
60 | Pelvic girdle muscle weakness (HP:0003749) | 2.04431032 |
61 | Acute myeloid leukemia (HP:0004808) | 2.04380789 |
62 | Vertebral arch anomaly (HP:0008438) | 2.04068543 |
63 | Prominent nose (HP:0000448) | 2.02523377 |
64 | Truncal obesity (HP:0001956) | 2.01753723 |
65 | Abnormality of the calcaneus (HP:0008364) | 2.01560786 |
66 | Deep palmar crease (HP:0006191) | 2.00819265 |
67 | Narrow palate (HP:0000189) | 1.98691622 |
68 | Hepatoblastoma (HP:0002884) | 1.98333701 |
69 | Abnormality of the diencephalon (HP:0010662) | 1.97415652 |
70 | Progressive external ophthalmoplegia (HP:0000590) | 1.95448140 |
71 | Anal stenosis (HP:0002025) | 1.95149586 |
72 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.95088144 |
73 | Duplication of thumb phalanx (HP:0009942) | 1.94966265 |
74 | Insidious onset (HP:0003587) | 1.93099985 |
75 | Termporal pattern (HP:0011008) | 1.93099985 |
76 | Increased density of long bones (HP:0006392) | 1.92692938 |
77 | Urethral obstruction (HP:0000796) | 1.92594525 |
78 | Pointed chin (HP:0000307) | 1.91739632 |
79 | Heterotopia (HP:0002282) | 1.91457993 |
80 | Abnormality of oral frenula (HP:0000190) | 1.90793648 |
81 | Multiple enchondromatosis (HP:0005701) | 1.90551170 |
82 | Turricephaly (HP:0000262) | 1.89584658 |
83 | Short middle phalanx of the 5th finger (HP:0004220) | 1.88618933 |
84 | Basal cell carcinoma (HP:0002671) | 1.88518107 |
85 | Skull defect (HP:0001362) | 1.88320603 |
86 | Dysmetric saccades (HP:0000641) | 1.88151640 |
87 | Ectopic kidney (HP:0000086) | 1.87759283 |
88 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.87457325 |
89 | Deep philtrum (HP:0002002) | 1.86086138 |
90 | Long palpebral fissure (HP:0000637) | 1.85988200 |
91 | Embryonal neoplasm (HP:0002898) | 1.85835800 |
92 | Progressive muscle weakness (HP:0003323) | 1.85074516 |
93 | Hypoplastic labia majora (HP:0000059) | 1.84913458 |
94 | Broad phalanges of the hand (HP:0009768) | 1.84531063 |
95 | Preauricular skin tag (HP:0000384) | 1.83306162 |
96 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.83159385 |
97 | Intestinal polyp (HP:0005266) | 1.82701309 |
98 | Uterine neoplasm (HP:0010784) | 1.81963576 |
99 | Transitional cell carcinoma of the bladder (HP:0006740) | 1.81437992 |
100 | Cafe-au-lait spot (HP:0000957) | 1.81415788 |
101 | Broad palm (HP:0001169) | 1.79870038 |
102 | Intestinal polyposis (HP:0200008) | 1.79466997 |
103 | Midline defect of the nose (HP:0004122) | 1.79268892 |
104 | Deviation of the hallux (HP:0010051) | 1.79248104 |
105 | Spinal cord lesions (HP:0100561) | 1.79133885 |
106 | Syringomyelia (HP:0003396) | 1.79133885 |
107 | Hallux valgus (HP:0001822) | 1.77767235 |
108 | Oligodactyly (HP:0012165) | 1.77445839 |
109 | Abnormality of abdominal situs (HP:0011620) | 1.75246569 |
110 | Abdominal situs inversus (HP:0003363) | 1.75246569 |
111 | Low anterior hairline (HP:0000294) | 1.74678053 |
112 | Hypoplasia of the maxilla (HP:0000327) | 1.74551985 |
113 | Asymmetry of the thorax (HP:0001555) | 1.73697979 |
114 | Morphological abnormality of the inner ear (HP:0011390) | 1.73528454 |
115 | Shoulder girdle muscle weakness (HP:0003547) | 1.73246422 |
116 | Abnormality of the salivary glands (HP:0010286) | 1.72960461 |
117 | Bladder carcinoma (HP:0002862) | 1.72757703 |
118 | Bladder neoplasm (HP:0009725) | 1.72757703 |
119 | Broad finger (HP:0001500) | 1.72382458 |
120 | Fibrous tissue neoplasm (HP:0012316) | 1.72128826 |
121 | Abnormality of the phalanges of the hallux (HP:0010057) | 1.71855601 |
122 | Missing ribs (HP:0000921) | 1.71802861 |
123 | Leiomyosarcoma (HP:0100243) | 1.71055686 |
124 | Uterine leiomyosarcoma (HP:0002891) | 1.71055686 |
125 | Short phalanx of the thumb (HP:0009660) | 1.71002217 |
126 | High pitched voice (HP:0001620) | 1.70773971 |
127 | Abnormality of chromosome segregation (HP:0002916) | 1.70701017 |
128 | Limited elbow extension (HP:0001377) | 1.70648310 |
129 | Bowel diverticulosis (HP:0005222) | 1.70469761 |
130 | Intestinal fistula (HP:0100819) | 1.70420613 |
131 | Enlarged penis (HP:0000040) | 1.70296823 |
132 | Patellar dislocation (HP:0002999) | 1.70111630 |
133 | Abnormality of the parietal bone (HP:0002696) | 1.69611220 |
134 | Increased number of teeth (HP:0011069) | 1.69456422 |
135 | Bowel incontinence (HP:0002607) | 1.68799826 |
136 | Metaphyseal cupping (HP:0003021) | 1.68617563 |
137 | Smooth philtrum (HP:0000319) | 1.67851395 |
138 | Intestinal malrotation (HP:0002566) | 1.67555251 |
139 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 1.67189633 |
140 | Short 1st metacarpal (HP:0010034) | 1.67189633 |
141 | 11 pairs of ribs (HP:0000878) | 1.66912798 |
142 | Orthostatic hypotension (HP:0001278) | 1.66487233 |
143 | Relative macrocephaly (HP:0004482) | 1.66243194 |
144 | Ulnar bowing (HP:0003031) | 1.65659979 |
145 | Radioulnar synostosis (HP:0002974) | 1.65586376 |
146 | Thin ribs (HP:0000883) | 1.65127279 |
147 | Attention deficit hyperactivity disorder (HP:0007018) | 1.63795733 |
148 | Sandal gap (HP:0001852) | 1.63254175 |
149 | Septate vagina (HP:0001153) | 1.61387004 |
150 | Short middle phalanx of finger (HP:0005819) | 1.61358274 |
151 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.58271998 |
152 | Aplasia of the phalanges of the hand (HP:0009802) | 1.58271998 |
153 | Aplasia involving bones of the extremities (HP:0009825) | 1.58271998 |
154 | Spastic diplegia (HP:0001264) | 1.56560325 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CDC7 | 4.52692179 |
2 | CDK12 | 3.92820384 |
3 | SMG1 | 3.09755562 |
4 | NEK2 | 2.77235621 |
5 | EEF2K | 2.67473499 |
6 | MKNK1 | 2.66060593 |
7 | MAP3K10 | 2.51926420 |
8 | PKN2 | 2.50000111 |
9 | BRD4 | 2.40214700 |
10 | MKNK2 | 2.17840785 |
11 | WEE1 | 2.16816395 |
12 | LATS1 | 2.15231615 |
13 | CDK6 | 2.02232967 |
14 | ALK | 1.98238602 |
15 | TAF1 | 1.94850941 |
16 | PNCK | 1.92324653 |
17 | NEK1 | 1.90665552 |
18 | SRPK1 | 1.90375141 |
19 | TRIB3 | 1.88194150 |
20 | FGFR4 | 1.84778950 |
21 | TTK | 1.80354388 |
22 | PASK | 1.74216933 |
23 | PRPF4B | 1.71805596 |
24 | SCYL2 | 1.68392073 |
25 | CDK4 | 1.64491290 |
26 | RPS6KB2 | 1.60910569 |
27 | RPS6KA4 | 1.46157540 |
28 | ATR | 1.45646686 |
29 | TSSK6 | 1.44531526 |
30 | CAMK1G | 1.40392379 |
31 | PLK3 | 1.39569729 |
32 | CHEK1 | 1.39307793 |
33 | PTK6 | 1.35767008 |
34 | CDK7 | 1.28311054 |
35 | PDGFRA | 1.26670427 |
36 | FGFR1 | 1.24486012 |
37 | AURKB | 1.22542324 |
38 | STK10 | 1.21250876 |
39 | PLK1 | 1.20424537 |
40 | MTOR | 1.20022682 |
41 | RIPK1 | 1.17726079 |
42 | ATM | 1.15933823 |
43 | CAMK1D | 1.14224948 |
44 | BRSK2 | 1.12460566 |
45 | STK24 | 1.09203014 |
46 | MAP3K8 | 1.07101618 |
47 | TGFBR1 | 1.06978365 |
48 | PAK4 | 1.06727905 |
49 | STK3 | 1.06565342 |
50 | CDK2 | 1.06480250 |
51 | ERBB3 | 1.06096790 |
52 | CHEK2 | 1.05856767 |
53 | BUB1 | 1.05630131 |
54 | VRK2 | 1.03315947 |
55 | LRRK2 | 1.02685021 |
56 | DYRK3 | 0.94554913 |
57 | KSR2 | 0.92665771 |
58 | MAP3K13 | 0.91604933 |
59 | SIK2 | 0.91604504 |
60 | MAP3K9 | 0.91061620 |
61 | CSNK1A1L | 0.90295158 |
62 | MELK | 0.87641612 |
63 | CDK1 | 0.86775722 |
64 | CSNK1E | 0.84264840 |
65 | SIK1 | 0.82077657 |
66 | CLK1 | 0.80149844 |
67 | PAK2 | 0.79364895 |
68 | EIF2AK1 | 0.75812534 |
69 | CDK9 | 0.73316124 |
70 | YES1 | 0.72836406 |
71 | PRKDC | 0.71165526 |
72 | DMPK | 0.70756276 |
73 | ICK | 0.70081359 |
74 | TYRO3 | 0.70023981 |
75 | NME2 | 0.69566751 |
76 | PBK | 0.68314504 |
77 | FGFR3 | 0.66646728 |
78 | NTRK1 | 0.66641347 |
79 | LATS2 | 0.65795256 |
80 | KSR1 | 0.65747044 |
81 | FGFR2 | 0.65196239 |
82 | PDGFRB | 0.65055367 |
83 | CSNK1D | 0.64925192 |
84 | ERBB2 | 0.64785074 |
85 | MAP3K14 | 0.63922756 |
86 | BRSK1 | 0.62016683 |
87 | MAPK14 | 0.61552172 |
88 | CDK3 | 0.59845684 |
89 | CDK11A | 0.59185566 |
90 | HIPK2 | 0.57371457 |
91 | EPHB2 | 0.55682530 |
92 | EIF2AK2 | 0.55562619 |
93 | CDK15 | 0.54472030 |
94 | UHMK1 | 0.52193964 |
95 | BMX | 0.51698788 |
96 | CDK18 | 0.51681099 |
97 | AKT2 | 0.51605659 |
98 | GSK3B | 0.50007747 |
99 | ACVR1B | 0.49372704 |
100 | CSNK1G1 | 0.47922214 |
101 | CDK8 | 0.47612686 |
102 | TTN | 0.46764809 |
103 | DYRK1B | 0.46581719 |
104 | CSNK2A2 | 0.46268706 |
105 | AKT1 | 0.45233344 |
106 | PRKD3 | 0.44892931 |
107 | MAPK10 | 0.44640414 |
108 | IRAK3 | 0.43794867 |
109 | BRAF | 0.43342219 |
110 | CSNK1G3 | 0.42465107 |
111 | CDK14 | 0.41765367 |
112 | CSNK1G2 | 0.41477406 |
113 | PTK2 | 0.41060774 |
114 | MAPK1 | 0.40615419 |
115 | AURKA | 0.40443756 |
116 | FRK | 0.40130807 |
117 | DDR2 | 0.39684053 |
118 | TNIK | 0.39569404 |
119 | PLK4 | 0.38852493 |
120 | ERBB4 | 0.38392217 |
121 | STK4 | 0.38128746 |
122 | MAPK9 | 0.36170558 |
123 | MAPK8 | 0.35929213 |
124 | RPS6KB1 | 0.35640333 |
125 | WNK1 | 0.35470410 |
126 | CDC42BPA | 0.34594878 |
127 | RET | 0.32202788 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * Spliceosome_Homo sapiens_hsa03040 | 2.97552635 |
2 | DNA replication_Homo sapiens_hsa03030 | 2.90045281 |
3 | RNA transport_Homo sapiens_hsa03013 | 2.79805266 |
4 | Cell cycle_Homo sapiens_hsa04110 | 2.73877757 |
5 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 2.64912529 |
6 | Mismatch repair_Homo sapiens_hsa03430 | 2.57648389 |
7 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.89856934 |
8 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.87283547 |
9 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.81140096 |
10 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.75411136 |
11 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.75229714 |
12 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.73245225 |
13 | Colorectal cancer_Homo sapiens_hsa05210 | 1.63303128 |
14 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.60937917 |
15 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.57620023 |
16 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.56954227 |
17 | Adherens junction_Homo sapiens_hsa04520 | 1.53317675 |
18 | Base excision repair_Homo sapiens_hsa03410 | 1.50806701 |
19 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.48954276 |
20 | RNA degradation_Homo sapiens_hsa03018 | 1.45392578 |
21 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.45268461 |
22 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.43080437 |
23 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.43011663 |
24 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.40522275 |
25 | Lysine degradation_Homo sapiens_hsa00310 | 1.39164869 |
26 | Endometrial cancer_Homo sapiens_hsa05213 | 1.38152585 |
27 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.33631882 |
28 | Thyroid cancer_Homo sapiens_hsa05216 | 1.32698729 |
29 | HTLV-I infection_Homo sapiens_hsa05166 | 1.31003496 |
30 | Ribosome_Homo sapiens_hsa03010 | 1.30330858 |
31 | Homologous recombination_Homo sapiens_hsa03440 | 1.29704910 |
32 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.28227083 |
33 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.27285545 |
34 | Wnt signaling pathway_Homo sapiens_hsa04310 | 1.24304864 |
35 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.24220283 |
36 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.23729556 |
37 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.22995731 |
38 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.22605823 |
39 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.22240861 |
40 | Prostate cancer_Homo sapiens_hsa05215 | 1.20687562 |
41 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.18200023 |
42 | Glioma_Homo sapiens_hsa05214 | 1.12724583 |
43 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.12194249 |
44 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.10373345 |
45 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.04543524 |
46 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.02705664 |
47 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.02198049 |
48 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.01028494 |
49 | Viral myocarditis_Homo sapiens_hsa05416 | 1.00435954 |
50 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.96678225 |
51 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.95052304 |
52 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.94253171 |
53 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.94195776 |
54 | Prion diseases_Homo sapiens_hsa05020 | 0.94099628 |
55 | Bladder cancer_Homo sapiens_hsa05219 | 0.93610793 |
56 | Pathways in cancer_Homo sapiens_hsa05200 | 0.91490366 |
57 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.89332705 |
58 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.89316940 |
59 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.87450358 |
60 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.87260503 |
61 | Hepatitis B_Homo sapiens_hsa05161 | 0.86092129 |
62 | Tight junction_Homo sapiens_hsa04530 | 0.81035002 |
63 | Focal adhesion_Homo sapiens_hsa04510 | 0.78570001 |
64 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.77932290 |
65 | Melanogenesis_Homo sapiens_hsa04916 | 0.77300095 |
66 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.76675504 |
67 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.76381654 |
68 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.75920066 |
69 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.74699971 |
70 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.74432157 |
71 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.73509133 |
72 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.73476997 |
73 | Long-term potentiation_Homo sapiens_hsa04720 | 0.73230186 |
74 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.72474491 |
75 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.71569246 |
76 | Melanoma_Homo sapiens_hsa05218 | 0.71003123 |
77 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.70493594 |
78 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.69173094 |
79 | Carbon metabolism_Homo sapiens_hsa01200 | 0.67334145 |
80 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.66890016 |
81 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.66539763 |
82 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.66247920 |
83 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.63807812 |
84 | Basal transcription factors_Homo sapiens_hsa03022 | 0.60203275 |
85 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.60051975 |
86 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.58410976 |
87 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.58161318 |
88 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.57817657 |
89 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.57581158 |
90 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.57467012 |
91 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.54849023 |
92 | Platelet activation_Homo sapiens_hsa04611 | 0.53777749 |
93 | Gap junction_Homo sapiens_hsa04540 | 0.53678962 |
94 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.53505389 |
95 | Axon guidance_Homo sapiens_hsa04360 | 0.53058453 |
96 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.52727032 |
97 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.52267437 |
98 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.52066909 |
99 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.49527943 |
100 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.47481127 |
101 | Apoptosis_Homo sapiens_hsa04210 | 0.47319454 |
102 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.47156801 |
103 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.46786234 |
104 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.46724394 |
105 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.46580176 |
106 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.45744660 |
107 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.43997732 |
108 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.42618832 |
109 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.41100480 |
110 | Insulin resistance_Homo sapiens_hsa04931 | 0.40853837 |
111 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.40027314 |
112 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.39830044 |
113 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.39279363 |
114 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.39001823 |
115 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.38960862 |
116 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.38956629 |
117 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.38891917 |
118 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.38855298 |
119 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.38223049 |
120 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.34706238 |
121 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.34200254 |