HNRNPA3P13

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1one-carbon compound transport (GO:0019755)9.55825624
2polyol transport (GO:0015791)9.23498427
3epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.11814915
4protein neddylation (GO:0045116)6.54645870
5cofactor catabolic process (GO:0051187)6.02080572
6spermatid nucleus differentiation (GO:0007289)5.87136751
7negative regulation of macrophage differentiation (GO:0045650)5.85031706
8regulation of platelet-derived growth factor receptor signaling pathway (GO:0010640)5.77188514
9regulation of cell-cell adhesion mediated by cadherin (GO:2000047)5.76905007
10regulation of tyrosine phosphorylation of Stat1 protein (GO:0042510)5.31115775
11negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642)5.17227436
12axonemal dynein complex assembly (GO:0070286)5.15273343
13nephron tubule development (GO:0072080)5.12785333
14phosphatidylinositol acyl-chain remodeling (GO:0036149)4.99333496
15G-protein coupled receptor internalization (GO:0002031)4.88120383
16negative regulation of T cell differentiation in thymus (GO:0033085)4.69662466
17auditory receptor cell stereocilium organization (GO:0060088)4.54305838
18regulation of Golgi to plasma membrane protein transport (GO:0042996)4.45327324
19phosphatidylserine acyl-chain remodeling (GO:0036150)4.41353735
20renal tubule development (GO:0061326)4.38731360
21facial nerve structural organization (GO:0021612)4.32616948
22negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804)4.18918388
23phosphatidylglycerol acyl-chain remodeling (GO:0036148)4.11429236
24water-soluble vitamin biosynthetic process (GO:0042364)4.10674193
25forebrain morphogenesis (GO:0048853)4.07121734
26viral transcription (GO:0019083)4.05324794
27cilium or flagellum-dependent cell motility (GO:0001539)4.04921075
28anterograde synaptic vesicle transport (GO:0048490)4.04750493
29nephron epithelium development (GO:0072009)3.97280418
30intracellular pH reduction (GO:0051452)3.94783571
31regulation of prostaglandin secretion (GO:0032306)3.94670381
32translational termination (GO:0006415)3.92534016
33photoreceptor cell maintenance (GO:0045494)3.86541391
34epithelial cilium movement (GO:0003351)3.86396533
35GTP biosynthetic process (GO:0006183)3.85241278
36cell proliferation in forebrain (GO:0021846)3.77606153
37positive regulation of lamellipodium assembly (GO:0010592)3.74527132
38negative regulation of histone acetylation (GO:0035067)3.71236221
39positive regulation of prostaglandin secretion (GO:0032308)3.71175997
40UTP biosynthetic process (GO:0006228)3.67420219
41ribosomal small subunit assembly (GO:0000028)3.63080540
42branching involved in labyrinthine layer morphogenesis (GO:0060670)3.60365808
43positive regulation of histone H3-K4 methylation (GO:0051571)3.58083855
44carnitine metabolic process (GO:0009437)3.57335645
45phosphatidylethanolamine acyl-chain remodeling (GO:0036152)3.55942568
46negative regulation of telomere maintenance (GO:0032205)3.55416978
47glycoprotein catabolic process (GO:0006516)3.54164369
48rRNA catabolic process (GO:0016075)3.45852907
49inner ear receptor stereocilium organization (GO:0060122)3.41663699
50positive regulation of gluconeogenesis (GO:0045722)3.41203151
51pH reduction (GO:0045851)3.40406666
52quinone metabolic process (GO:1901661)3.39377234
53apical protein localization (GO:0045176)3.38601917
54maturation of 5.8S rRNA (GO:0000460)3.33589022
55positive regulation of phosphoprotein phosphatase activity (GO:0032516)3.31176100
56mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.28195843
57histone H3-K9 methylation (GO:0051567)3.28026929
58UTP metabolic process (GO:0046051)3.23484343
59regulation of growth hormone secretion (GO:0060123)3.22874972
60translational elongation (GO:0006414)3.21819299
61pyrimidine nucleobase catabolic process (GO:0006208)3.20696615
62regulation of integrin activation (GO:0033623)3.19941140
63positive regulation of growth hormone secretion (GO:0060124)3.19815341
64ether lipid metabolic process (GO:0046485)3.19564580
65negative regulation of lipid storage (GO:0010888)3.15855001
66SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.15631174
67regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)3.14057772
68cranial nerve structural organization (GO:0021604)3.12669972
69forebrain neuron development (GO:0021884)3.09147876
70ATP synthesis coupled proton transport (GO:0015986)3.07820791
71energy coupled proton transport, down electrochemical gradient (GO:0015985)3.07820791
72cotranslational protein targeting to membrane (GO:0006613)3.07435586
73protein targeting to ER (GO:0045047)3.02809591
74cellular protein complex disassembly (GO:0043624)3.02763611
75cilium movement (GO:0003341)3.01544546
76positive regulation of tyrosine phosphorylation of Stat1 protein (GO:0042511)3.01078776
77icosanoid secretion (GO:0032309)3.01075891
78arachidonic acid secretion (GO:0050482)3.01075891
79DNA damage response, detection of DNA damage (GO:0042769)2.95412191
80short-term memory (GO:0007614)2.94798371
81protein localization to endoplasmic reticulum (GO:0070972)2.92914907
82transcription from mitochondrial promoter (GO:0006390)2.92456384
83positive regulation of cAMP-mediated signaling (GO:0043950)2.92360111
84phosphatidylcholine acyl-chain remodeling (GO:0036151)2.92354145
85negative regulation of peptidyl-lysine acetylation (GO:2000757)2.92077722
86nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.91060430
87ribosomal large subunit biogenesis (GO:0042273)2.90854019
88response to redox state (GO:0051775)2.90355508
89establishment of protein localization to endoplasmic reticulum (GO:0072599)2.88279996
90positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.81929617
91translational initiation (GO:0006413)2.80520011
92anterograde axon cargo transport (GO:0008089)2.75691625
93oxidative phosphorylation (GO:0006119)2.74699098
94germ cell migration (GO:0008354)2.72841002
95cell wall macromolecule catabolic process (GO:0016998)2.71034003
96auditory behavior (GO:0031223)2.70817354
97regulation of stem cell maintenance (GO:2000036)2.70789899
98mitochondrion degradation (GO:0000422)2.69547127
99guanosine-containing compound biosynthetic process (GO:1901070)2.66616687
100coenzyme catabolic process (GO:0009109)10.2286840

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.06095402
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.83332002
3RBPJ_22232070_ChIP-Seq_NCS_Mouse3.38257755
4FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.20646878
5SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.03360052
6ZNF274_21170338_ChIP-Seq_K562_Hela2.92617349
7HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.91351062
8TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.56587009
9TP63_19390658_ChIP-ChIP_HaCaT_Human2.53486402
10VDR_22108803_ChIP-Seq_LS180_Human2.40774366
11TAF15_26573619_Chip-Seq_HEK293_Human2.35946999
12ELF1_17652178_ChIP-ChIP_JURKAT_Human2.32628709
13RCOR2_21632747_ChIP-Seq_MESCs_Mouse2.15909289
14CBX2_27304074_Chip-Seq_ESCs_Mouse2.10716973
15IRF1_19129219_ChIP-ChIP_H3396_Human2.04468091
16BMI1_23680149_ChIP-Seq_NPCS_Mouse1.98886522
17MYC_18940864_ChIP-ChIP_HL60_Human1.96202107
18CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.95207451
19EZH2_27304074_Chip-Seq_ESCs_Mouse1.90829239
20EWS_26573619_Chip-Seq_HEK293_Human1.90123795
21CTBP1_25329375_ChIP-Seq_LNCAP_Human1.87653589
22YY1_21170310_ChIP-Seq_MESCs_Mouse1.80934631
23GABP_17652178_ChIP-ChIP_JURKAT_Human1.80428811
24ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.75832449
25REST_21632747_ChIP-Seq_MESCs_Mouse1.75715949
26IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.70299111
27CBP_20019798_ChIP-Seq_JUKART_Human1.70299111
28ZFP57_27257070_Chip-Seq_ESCs_Mouse1.69616562
29P300_19829295_ChIP-Seq_ESCs_Human1.68736022
30JARID2_20064375_ChIP-Seq_MESCs_Mouse1.61341632
31FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.57517529
32RNF2_27304074_Chip-Seq_NSC_Mouse1.52714568
33EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.50265935
34GBX2_23144817_ChIP-Seq_PC3_Human1.45504651
35POU5F1_16153702_ChIP-ChIP_HESCs_Human1.45424449
36MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.43350055
37P53_22127205_ChIP-Seq_FIBROBLAST_Human1.43035279
38CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.39957053
39HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.38768537
40FUS_26573619_Chip-Seq_HEK293_Human1.37503834
41ETV2_25802403_ChIP-Seq_MESCs_Mouse1.36159776
42RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.35573135
43EZH2_27294783_Chip-Seq_ESCs_Mouse1.34309328
44FLI1_27457419_Chip-Seq_LIVER_Mouse1.34193341
45RNF2_27304074_Chip-Seq_ESCs_Mouse1.32131385
46RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.30582950
47CTBP2_25329375_ChIP-Seq_LNCAP_Human1.28935483
48GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.28790564
49TOP2B_26459242_ChIP-Seq_MCF-7_Human1.28763184
50IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.28405175
51NCOR_22424771_ChIP-Seq_293T_Human1.27878781
52NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.25677823
53TCF4_22108803_ChIP-Seq_LS180_Human1.24457968
54WDR5_24793694_ChIP-Seq_LNCAP_Human1.24026888
55SUZ12_27294783_Chip-Seq_ESCs_Mouse1.22702998
56JARID2_20075857_ChIP-Seq_MESCs_Mouse1.20618160
57MYC_19829295_ChIP-Seq_ESCs_Human1.18891743
58ER_23166858_ChIP-Seq_MCF-7_Human1.17287511
59EED_16625203_ChIP-ChIP_MESCs_Mouse1.17018049
60TTF2_22483619_ChIP-Seq_HELA_Human1.16140274
61ETS1_20019798_ChIP-Seq_JURKAT_Human1.14319908
62REST_18959480_ChIP-ChIP_MESCs_Mouse1.12998617
63SMAD4_21799915_ChIP-Seq_A2780_Human1.12499630
64RUNX2_22187159_ChIP-Seq_PCA_Human1.11830758
65TP53_16413492_ChIP-PET_HCT116_Human1.11801415
66GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.11225262
67SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.09462125
68EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.04962421
69SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.04379031
70TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.03407892
71CDX2_22108803_ChIP-Seq_LS180_Human1.03296899
72SMAD3_21741376_ChIP-Seq_EPCs_Human1.02971940
73SOX2_18555785_ChIP-Seq_MESCs_Mouse1.02321890
74VDR_23849224_ChIP-Seq_CD4+_Human1.02054423
75ESET_19884257_ChIP-Seq_ESCs_Mouse1.02003797
76RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.00152642
77HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.99767358
78EST1_17652178_ChIP-ChIP_JURKAT_Human0.98878264
79TAL1_26923725_Chip-Seq_HPCs_Mouse0.97861284
80KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.97857385
81TAF2_19829295_ChIP-Seq_ESCs_Human0.97534730
82MYC_18555785_ChIP-Seq_MESCs_Mouse0.96979513
83SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.96905047
84SOX2_16153702_ChIP-ChIP_HESCs_Human0.94904987
85SMAD3_21741376_ChIP-Seq_ESCs_Human0.93995964
86RING1B_27294783_Chip-Seq_ESCs_Mouse0.92245688
87SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.91986067
88IKZF1_21737484_ChIP-ChIP_HCT116_Human0.91382356
89SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.90198532
90KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.90169268
91KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.90169268
92KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.90169268
93SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.89369657
94UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.88378089
95GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87391500
96BCAT_22108803_ChIP-Seq_LS180_Human0.86987426
97IGF1R_20145208_ChIP-Seq_DFB_Human0.84949638
98SOX2_21211035_ChIP-Seq_LN229_Human0.84933455
99KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.83515327
100NANOG_19829295_ChIP-Seq_ESCs_Human0.82560819

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000566_synostosis5.31745013
2MP0001188_hyperpigmentation4.64936411
3MP0004742_abnormal_vestibular_system4.09364438
4MP0004147_increased_porphyrin_level3.70651600
5MP0005084_abnormal_gallbladder_morpholo3.66593197
6MP0002009_preneoplasia3.42791343
7MP0002138_abnormal_hepatobiliary_system3.34807249
8MP0005410_abnormal_fertilization3.30304437
9MP0004885_abnormal_endolymph2.85428198
10MP0006276_abnormal_autonomic_nervous2.69814043
11MP0006292_abnormal_olfactory_placode2.59523241
12MP0002160_abnormal_reproductive_system2.33924164
13MP0003878_abnormal_ear_physiology2.32231046
14MP0005377_hearing/vestibular/ear_phenot2.32231046
15MP0009840_abnormal_foam_cell2.27254897
16MP0002877_abnormal_melanocyte_morpholog2.23071144
17MP0002928_abnormal_bile_duct2.18900017
18MP0001485_abnormal_pinna_reflex2.01605754
19MP0002909_abnormal_adrenal_gland1.87934502
20MP0005389_reproductive_system_phenotype1.82534035
21MP0001664_abnormal_digestion1.78092411
22MP0003879_abnormal_hair_cell1.66656994
23MP0003123_paternal_imprinting1.65356468
24MP0001529_abnormal_vocalization1.58961797
25MP0002166_altered_tumor_susceptibility1.58890395
26MP0001968_abnormal_touch/_nociception1.55001465
27MP0002735_abnormal_chemical_nociception1.43534558
28MP0005551_abnormal_eye_electrophysiolog1.36718026
29MP0003880_abnormal_central_pattern1.36050504
30MP0002822_catalepsy1.36011190
31MP0001919_abnormal_reproductive_system1.34926707
32MP0003191_abnormal_cellular_cholesterol1.33635074
33MP0002006_tumorigenesis1.32364248
34MP0008877_abnormal_DNA_methylation1.29189467
35MP0008789_abnormal_olfactory_epithelium1.27222799
36MP0005423_abnormal_somatic_nervous1.24438311
37MP0005645_abnormal_hypothalamus_physiol1.22079678
38MP0002272_abnormal_nervous_system1.21954344
39MP0003122_maternal_imprinting1.15914862
40MP0002234_abnormal_pharynx_morphology1.15672113
41MP0000631_abnormal_neuroendocrine_gland1.15381184
42MP0003635_abnormal_synaptic_transmissio1.15210021
43MP0009278_abnormal_bone_marrow1.13462032
44MP0001986_abnormal_taste_sensitivity1.13077252
45MP0003567_abnormal_fetal_cardiomyocyte1.08113478
46MP0003937_abnormal_limbs/digits/tail_de1.07005970
47MP0001963_abnormal_hearing_physiology1.04087785
48MP0008569_lethality_at_weaning1.02924777
49MP0004264_abnormal_extraembryonic_tissu1.02912211
50MP0003943_abnormal_hepatobiliary_system1.02892585
51MP0005499_abnormal_olfactory_system1.01999246
52MP0005394_taste/olfaction_phenotype1.01999246
53MP0002063_abnormal_learning/memory/cond1.01393990
54MP0009745_abnormal_behavioral_response1.01040109
55MP0002736_abnormal_nociception_after1.01032656
56MP0005646_abnormal_pituitary_gland1.00078148
57MP0000026_abnormal_inner_ear0.99636628
58MP0001984_abnormal_olfaction0.97209124
59MP0002572_abnormal_emotion/affect_behav0.97094815
60MP0008004_abnormal_stomach_pH0.94770989
61MP0003698_abnormal_male_reproductive0.93610872
62MP0000778_abnormal_nervous_system0.93585138
63MP0005397_hematopoietic_system_phenotyp0.93533039
64MP0001545_abnormal_hematopoietic_system0.93533039
65MP0002752_abnormal_somatic_nervous0.92896958
66MP0008007_abnormal_cellular_replicative0.92614069
67MP0003763_abnormal_thymus_physiology0.91840005
68MP0005253_abnormal_eye_physiology0.91772361
69MP0002938_white_spotting0.89699378
70MP0001905_abnormal_dopamine_level0.89686958
71MP0004130_abnormal_muscle_cell0.88855987
72MP0004484_altered_response_of0.86746964
73MP0001270_distended_abdomen0.86657969
74MP0002557_abnormal_social/conspecific_i0.84080157
75MP0000049_abnormal_middle_ear0.83644441
76MP0002734_abnormal_mechanical_nocicepti0.81096588
77MP0003950_abnormal_plasma_membrane0.80862740
78MP0001440_abnormal_grooming_behavior0.80563801
79MP0001970_abnormal_pain_threshold0.79713078
80MP0003942_abnormal_urinary_system0.79644166
81MP0001486_abnormal_startle_reflex0.76834814
82MP0003718_maternal_effect0.76637493
83MP0000427_abnormal_hair_cycle0.75960112
84MP0001293_anophthalmia0.75395737
85MP0002733_abnormal_thermal_nociception0.75152808
86MP0003385_abnormal_body_wall0.75115947
87MP0001879_abnormal_lymphatic_vessel0.75044642
88MP0003119_abnormal_digestive_system0.73021065
89MP0002653_abnormal_ependyma_morphology0.72831647
90MP0003633_abnormal_nervous_system0.71849291
91MP0005448_abnormal_energy_balance0.70647933
92MP0002177_abnormal_outer_ear0.68731041
93MP0002067_abnormal_sensory_capabilities0.67169843
94MP0005671_abnormal_response_to0.67028641
95MP0003252_abnormal_bile_duct0.66729613
96MP0005365_abnormal_bile_salt0.66565768
97MP0008872_abnormal_physiological_respon0.65912944
98MP0003866_abnormal_defecation0.64623148
99MP0001929_abnormal_gametogenesis0.64279445
100MP0000678_abnormal_parathyroid_gland0.63538617

Predicted human phenotypes

RankGene SetZ-score
1Absent rod-and cone-mediated responses on ERG (HP:0007688)8.58230447
2Abnormal ciliary motility (HP:0012262)6.58249495
3Abnormal respiratory motile cilium morphology (HP:0005938)6.52578759
4Abnormal respiratory epithelium morphology (HP:0012253)6.52578759
5Abnormal respiratory motile cilium physiology (HP:0012261)5.28032192
6Abnormal rod and cone electroretinograms (HP:0008323)5.23759716
7Decreased central vision (HP:0007663)4.79413981
8Bony spicule pigmentary retinopathy (HP:0007737)4.53825504
9Attenuation of retinal blood vessels (HP:0007843)3.86097092
10Hyperglycinemia (HP:0002154)3.83219829
11Bile duct proliferation (HP:0001408)3.68380318
12Abnormal biliary tract physiology (HP:0012439)3.68380318
13Abnormality of serine family amino acid metabolism (HP:0010894)3.63808514
14Abnormality of glycine metabolism (HP:0010895)3.63808514
15Hyperglycinuria (HP:0003108)3.47459738
16Pendular nystagmus (HP:0012043)3.36259749
17Gonadal dysgenesis (HP:0000133)2.90339929
18Sensorimotor neuropathy (HP:0007141)2.76603856
193-Methylglutaconic aciduria (HP:0003535)2.75899486
20True hermaphroditism (HP:0010459)2.71958158
21Respiratory difficulties (HP:0002880)2.71023302
22Abnormality of dicarboxylic acid metabolism (HP:0010995)2.65421186
23Dicarboxylic aciduria (HP:0003215)2.65421186
24Supernumerary spleens (HP:0009799)2.64699479
25Multiple enchondromatosis (HP:0005701)2.60942661
26Impulsivity (HP:0100710)2.59702522
27Abnormality of lateral ventricle (HP:0030047)2.59531679
28Pancreatic fibrosis (HP:0100732)2.58813840
29Recurrent sinusitis (HP:0011108)2.58392275
30Chorioretinal atrophy (HP:0000533)2.56238286
31Constricted visual fields (HP:0001133)2.43864870
32Molar tooth sign on MRI (HP:0002419)2.43037917
33Abnormality of midbrain morphology (HP:0002418)2.43037917
34Optic nerve coloboma (HP:0000588)2.40853998
35Infertility (HP:0000789)2.36364877
36Renal cortical cysts (HP:0000803)2.33396622
37Pancreatic cysts (HP:0001737)2.33151243
38Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.32195235
39Type II lissencephaly (HP:0007260)2.30335857
40Hypoplasia of the uterus (HP:0000013)2.29712953
41Abnormality of the pons (HP:0007361)2.26047407
42Agitation (HP:0000713)2.23584877
43Decreased electroretinogram (ERG) amplitude (HP:0000654)2.22567822
44Increased corneal curvature (HP:0100692)2.20047916
45Keratoconus (HP:0000563)2.20047916
46Myokymia (HP:0002411)2.19132863
47Renal Fanconi syndrome (HP:0001994)2.17787501
48Abnormality of fatty-acid metabolism (HP:0004359)2.15793855
49Abnormal cartilage morphology (HP:0002763)2.14454598
50Abolished electroretinogram (ERG) (HP:0000550)2.10688919
51Abnormality of cells of the erythroid lineage (HP:0012130)2.10107887
52Abnormality of macular pigmentation (HP:0008002)2.08801342
53Polyphagia (HP:0002591)2.06676468
54Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.03338969
55Thyroid-stimulating hormone excess (HP:0002925)2.02471351
56Neoplasm of the adrenal cortex (HP:0100641)2.02253381
57Dynein arm defect of respiratory motile cilia (HP:0012255)10.4311193
58Absent/shortened dynein arms (HP:0200106)10.4311193
59Poor suck (HP:0002033)1.98819457
60Acute lymphatic leukemia (HP:0006721)1.97430082
61Enlarged penis (HP:0000040)1.92905952
62Turricephaly (HP:0000262)1.91801591
63Methylmalonic acidemia (HP:0002912)1.88355684
64Tachypnea (HP:0002789)1.88045991
65Cystic liver disease (HP:0006706)1.86837526
66Long foot (HP:0001833)1.86766764
67Abnormality of the fingertips (HP:0001211)1.85996817
68Hypoplasia of the pons (HP:0012110)1.85770417
69Palpebral edema (HP:0100540)1.84942339
70Chronic hepatic failure (HP:0100626)1.84122599
71Testicular neoplasm (HP:0010788)1.83282648
72Neoplasm of head and neck (HP:0012288)1.82851233
73Esophageal neoplasm (HP:0100751)1.82851233
74Nephronophthisis (HP:0000090)1.81907762
75Prolonged neonatal jaundice (HP:0006579)1.81770349
76Sclerocornea (HP:0000647)1.81454142
77Abnormal biliary tract morphology (HP:0012440)1.81280223
78Abnormality of the aortic arch (HP:0012303)1.81192358
79Abnormality of the renal cortex (HP:0011035)1.78599761
80Stenosis of the external auditory canal (HP:0000402)1.78585022
81Aplasia/hypoplasia of the uterus (HP:0008684)1.78510725
82Hypoplasia of the thymus (HP:0000778)1.76240852
83Cerebral palsy (HP:0100021)1.71988585
84Abnormality of the parietal bone (HP:0002696)1.69742999
85Brushfield spots (HP:0001088)1.69660993
86Septo-optic dysplasia (HP:0100842)1.68624280
87Cerebral edema (HP:0002181)1.68535117
88Male pseudohermaphroditism (HP:0000037)1.67620483
89Abnormality of serum amino acid levels (HP:0003112)1.67173021
90Congenital stationary night blindness (HP:0007642)1.64994897
91Failure to thrive in infancy (HP:0001531)1.62199565
92Death in childhood (HP:0003819)1.62124671
93Chronic bronchitis (HP:0004469)1.61971184
94Impaired vibration sensation in the lower limbs (HP:0002166)1.61785313
95Abnormality of the renal medulla (HP:0100957)1.61693121
96Increased hepatocellular lipid droplets (HP:0006565)1.61393143
97Acute encephalopathy (HP:0006846)1.60260542
98Chronic sinusitis (HP:0011109)1.59759873
99Metabolic acidosis (HP:0001942)1.58658761
100Scrotal hypoplasia (HP:0000046)1.58501291

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK195.96263741
2FRK5.81374528
3NEK23.83583426
4TAF13.48282992
5KIT2.71251759
6MATK2.39748312
7WNK32.38359207
8CASK2.34848806
9SIK22.09310140
10VRK21.95949432
11OXSR11.94082442
12DYRK21.92646876
13MAP2K31.88956567
14EIF2AK11.84455029
15JAK31.81228412
16CAMK1D1.72696452
17MAP3K31.57366459
18FGFR21.49128740
19VRK11.48248026
20STK381.45543709
21PRKG21.41935906
22CSNK1G31.39613436
23CSNK1A1L1.28736437
24DAPK21.24234042
25TYRO31.22631012
26MINK11.22076345
27ALK1.19326147
28CSNK1G11.19097999
29CSNK1G21.16723675
30MARK11.16708669
31FLT31.12207488
32TLK11.10533052
33WNK41.10018084
34CAMK1G1.03863834
35NEK10.98252569
36MAP2K70.96459158
37PLK30.94319710
38ADRBK20.94039155
39INSRR0.89738761
40RPS6KB20.87529874
41STK110.87138584
42SMG10.86255142
43PRKCH0.84617641
44STK390.83791518
45RPS6KA20.83784459
46PRKCZ0.83566206
47SGK30.80794863
48ILK0.80265026
49PRKCQ0.79592730
50GRK50.79226954
51GRK10.77806535
52TSSK60.76153730
53SGK20.75764463
54CHEK20.75161930
55DAPK10.74595445
56MKNK20.74478864
57DAPK30.73518213
58MAP3K60.73500388
59RPS6KA60.68657770
60MAPK130.68589965
61CSNK1E0.64790120
62RPS6KB10.63265897
63CSNK1D0.62766426
64CAMK40.60628415
65KSR10.60283841
66RPS6KL10.59498142
67RPS6KC10.59498142
68MARK30.59455380
69NUAK10.59327682
70PRKD30.57850234
71DYRK1A0.55698225
72SGK4940.54829248
73SGK2230.54829248
74MAP3K40.53813157
75DYRK30.52726417
76EIF2AK30.52524680
77PRKCD0.50757109
78ZAK0.50392094
79SGK10.49680608
80PLK10.48491909
81NTRK30.45358260
82TXK0.41988708
83SIK10.38271992
84PRKCA0.38069551
85PRKCG0.37906649
86PRKCE0.37332386
87MAPKAPK50.36229337
88CSNK2A20.35921017
89TIE10.33794080
90PRKACA0.32454746
91RPS6KA30.32274769
92MKNK10.31993679
93PRKG10.31813996
94RPS6KA10.31489576
95MAP3K10.30255221
96CDK50.27185928
97PRKACG0.26917547
98CAMK10.25830932
99PASK0.25344861
100MAP4K20.25153604

Predicted pathways (KEGG)

RankGene SetZ-score
1alpha-Linolenic acid metabolism_Homo sapiens_hsa005924.54865955
2Ribosome_Homo sapiens_hsa030104.28854291
3Linoleic acid metabolism_Homo sapiens_hsa005913.91220338
4Arachidonic acid metabolism_Homo sapiens_hsa005903.58374123
5Basal transcription factors_Homo sapiens_hsa030222.86384393
6Fat digestion and absorption_Homo sapiens_hsa049752.63899944
7Ether lipid metabolism_Homo sapiens_hsa005652.60789428
8Oxidative phosphorylation_Homo sapiens_hsa001902.15156152
9Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.06404997
10Parkinsons disease_Homo sapiens_hsa050122.03797236
11Propanoate metabolism_Homo sapiens_hsa006402.01629002
12Phototransduction_Homo sapiens_hsa047441.94174899
13Cardiac muscle contraction_Homo sapiens_hsa042601.93442995
14Fatty acid metabolism_Homo sapiens_hsa012121.87040080
15Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.84814344
16Renin secretion_Homo sapiens_hsa049241.82573037
17Fatty acid degradation_Homo sapiens_hsa000711.81007071
18Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.78807581
19Peroxisome_Homo sapiens_hsa041461.68870125
20Nicotine addiction_Homo sapiens_hsa050331.65275348
21Olfactory transduction_Homo sapiens_hsa047401.64608152
22Alzheimers disease_Homo sapiens_hsa050101.38920536
23Sulfur relay system_Homo sapiens_hsa041221.37630878
24Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.35851819
25Huntingtons disease_Homo sapiens_hsa050161.30181556
26Vascular smooth muscle contraction_Homo sapiens_hsa042701.29366768
27Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.28513223
28PPAR signaling pathway_Homo sapiens_hsa033201.28149015
29Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.26099014
30RNA transport_Homo sapiens_hsa030131.22718694
31Circadian entrainment_Homo sapiens_hsa047131.20789211
32Regulation of autophagy_Homo sapiens_hsa041401.18017943
33Pancreatic secretion_Homo sapiens_hsa049721.15383412
34p53 signaling pathway_Homo sapiens_hsa041151.11819114
35Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.11235294
36Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.11172614
37Morphine addiction_Homo sapiens_hsa050321.03294351
38Serotonergic synapse_Homo sapiens_hsa047261.02243283
39Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.98639597
40Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.98115217
41Glutamatergic synapse_Homo sapiens_hsa047240.97523414
42Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.92554094
43RNA polymerase_Homo sapiens_hsa030200.90880071
44Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.90127394
45RNA degradation_Homo sapiens_hsa030180.89748760
46Maturity onset diabetes of the young_Homo sapiens_hsa049500.88340842
47Caffeine metabolism_Homo sapiens_hsa002320.87378097
48Insulin secretion_Homo sapiens_hsa049110.85852886
49GABAergic synapse_Homo sapiens_hsa047270.78433746
50Chemical carcinogenesis_Homo sapiens_hsa052040.77540319
51Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.74484349
52ABC transporters_Homo sapiens_hsa020100.74466882
53Salivary secretion_Homo sapiens_hsa049700.73754373
54Dopaminergic synapse_Homo sapiens_hsa047280.72952495
55Sulfur metabolism_Homo sapiens_hsa009200.72383843
56Proteasome_Homo sapiens_hsa030500.71517260
57Gap junction_Homo sapiens_hsa045400.70895410
58N-Glycan biosynthesis_Homo sapiens_hsa005100.70314996
59Folate biosynthesis_Homo sapiens_hsa007900.69960300
60Axon guidance_Homo sapiens_hsa043600.68809334
61Long-term depression_Homo sapiens_hsa047300.68683429
62Protein export_Homo sapiens_hsa030600.67179686
63Gastric acid secretion_Homo sapiens_hsa049710.65335922
64One carbon pool by folate_Homo sapiens_hsa006700.64103459
65Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.64057396
66Transcriptional misregulation in cancer_Homo sapiens_hsa052020.62767901
67Ovarian steroidogenesis_Homo sapiens_hsa049130.62735198
68Taste transduction_Homo sapiens_hsa047420.61206357
69Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.60358098
70Amphetamine addiction_Homo sapiens_hsa050310.60246291
71Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.56715073
72Asthma_Homo sapiens_hsa053100.55307788
73Tryptophan metabolism_Homo sapiens_hsa003800.55281532
74Nitrogen metabolism_Homo sapiens_hsa009100.51975634
75Type II diabetes mellitus_Homo sapiens_hsa049300.51615463
76Intestinal immune network for IgA production_Homo sapiens_hsa046720.50365031
77Ras signaling pathway_Homo sapiens_hsa040140.50315292
78Steroid hormone biosynthesis_Homo sapiens_hsa001400.49141726
79Cocaine addiction_Homo sapiens_hsa050300.48339111
80Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.48222639
81Primary bile acid biosynthesis_Homo sapiens_hsa001200.47819203
82beta-Alanine metabolism_Homo sapiens_hsa004100.47195341
83Glycerophospholipid metabolism_Homo sapiens_hsa005640.45530913
84Metabolic pathways_Homo sapiens_hsa011000.45336240
85Fatty acid biosynthesis_Homo sapiens_hsa000610.41769140
86Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.41729261
87Glucagon signaling pathway_Homo sapiens_hsa049220.41624945
88Oxytocin signaling pathway_Homo sapiens_hsa049210.39282466
89Retinol metabolism_Homo sapiens_hsa008300.38921020
90cAMP signaling pathway_Homo sapiens_hsa040240.38372864
91cGMP-PKG signaling pathway_Homo sapiens_hsa040220.34960748
92Nucleotide excision repair_Homo sapiens_hsa034200.30540875
93Dorso-ventral axis formation_Homo sapiens_hsa043200.30504995
94MAPK signaling pathway_Homo sapiens_hsa040100.25938980
95Calcium signaling pathway_Homo sapiens_hsa040200.24958716
96Homologous recombination_Homo sapiens_hsa034400.22599276
97Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.21216277
98Lysosome_Homo sapiens_hsa041420.19748081
99Insulin resistance_Homo sapiens_hsa049310.18893768
100Platelet activation_Homo sapiens_hsa046110.18425745

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